Web Desc
Mitochondrial Dynamics
Organizer(s): Richard J. Youle and Gia K. Voeltz
Date: April 03 - 07, 2016
Location: Sheraton Steamboat Resort, Steamboat Springs, CO, USA
Sponsored by Merck & Co., Inc.
Summary of Meeting:
Although the realm of mitochondrial dynamics continues to expand as discoveries mount regarding its importance in physiology and medicine, we still do not understand why it is crucial to maintain eukaryotic cell integrity, and we are only beginning to understand the molecular mechanisms and regulation involved. This topic is attracting more and more interest and an increasing number of investigators as the critical role of mitochondrial dynamics has been found very recently to impact innate immunity, cell division and chemoresistance. This Keystone Symposia meeting will thus highlight the latest advances in diverse disciplines including neurology, aging, cancer research, autophagy, membrane morphogenesis, structural biology and bioenergetics. The program groups the best senior and junior scientists in these disciplines to break down barriers between different fields of research and promote innovation. As the most important discoveries in mitochondrial dynamics lie ahead, the interactions at this meeting should play a key role in their advance.
Scholarship Deadline: December 2 2015
Discounted Abstract Deadline: December 2 2015
Abstract Deadline: January 6 2016
Discounted Registration Deadline: February 3 2016
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Merck & Co., Inc.
We gratefully acknowledge additional support for this conference from:
Seahorse Bioscience, a part of Agilent Technologies
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Pfizer Inc.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, April 03 | 4:00PM - 8:00PM
Arrival and Registration
Room: Foyer


Sunday, April 03 | 6:00PM - 8:00PM
Welcome Mixer
Room: Foyer
No registration fees are used to fund alcohol served at this function.

Monday, April 04 | 7:00AM - 8:00AM
Breakfast
Room: Foyer/Rainbow/Twilight


Monday, April 04 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Storm Peak/Mt. Werner

Speaker 1 of 2
* Richard J. Youle, NINDS, National Institutes of Health, USA

Monday, April 04 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Storm Peak/Mt. Werner

Speaker 2 of 2
Bruce M. Spiegelman, Harvard Medical School, USA
White, Brown and Beige Fat: Basic Biology and a Novel Effector of Uncoupled Respiration

Monday, April 04 | 9:00AM - 11:45AM
Architecture of the Inner Mitochondrial Membrane
Room: Storm Peak/Mt. Werner

Speaker 1 of 4
* Thomas Langer, CECAD Research Center, Germany
Mitochondrial Membrane Scaffolds and Phospholipid Trafficking

Monday, April 04 | 9:00AM - 11:45AM
Architecture of the Inner Mitochondrial Membrane
Room: Storm Peak/Mt. Werner

Speaker 2 of 4
Agnieszka Chacinska, University of Warsaw, Poland
Cellular Responses to Defects in Mitochondrial Protein Biogenesis

Monday, April 04 | 9:00AM - 11:45AM
Architecture of the Inner Mitochondrial Membrane
Room: Storm Peak/Mt. Werner

Speaker 3 of 4
Nikolaus Pfanner, University of Freiburg, Germany
Mitochondrial Machineries for Protein Import and Assembly

Monday, April 04 | 9:00AM - 11:45AM
Architecture of the Inner Mitochondrial Membrane
Room: Storm Peak/Mt. Werner

Speaker 4 of 4
Luca Scorrano, University of Padova, Italy
Systemic Adaptation to Changes in Cristae Shape and Mitochondrial Dynamics

Monday, April 04 | 9:40AM - 10:00AM
Coffee Break
Room: Foyer


Monday, April 04 | 11:45AM - 2:30PM
On Own for Lunch


Monday, April 04 | 11:45AM - 1:00PM
Poster Setup
Room: Sunshine


Monday, April 04 | 1:00PM - 10:00PM
Poster Viewing
Room: Sunshine


Monday, April 04 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Monday, April 04 | 5:00PM - 7:30PM
Mitochondrial Fission and Fusion
Room: Storm Peak/Mt. Werner

Speaker 1 of 6
Adam Frost, University of California, San Francisco, USA
Cryo-EM Structure of a Mitochondrial Dynamin-Adaptor Complex

Monday, April 04 | 5:00PM - 7:30PM
Mitochondrial Fission and Fusion
Room: Storm Peak/Mt. Werner

Speaker 2 of 6
Mike Ryan, Monash University, Australia
Characterization of Mammalian Adaptors in Mitochondrial Division

Monday, April 04 | 5:00PM - 7:30PM
Mitochondrial Fission and Fusion
Room: Storm Peak/Mt. Werner

Speaker 3 of 6
* Jodi Nunnari, University of California, Davis, USA
The Function of the MICOS Complex

Monday, April 04 | 5:00PM - 7:30PM
Mitochondrial Fission and Fusion
Room: Storm Peak/Mt. Werner

Speaker 4 of 6
Mickael Cohen, CNRS-UPMC, France
Short Talk: Tethering Ring Structures Trigger Mitochondrial Fusion

Monday, April 04 | 5:00PM - 7:30PM
Mitochondrial Fission and Fusion
Room: Storm Peak/Mt. Werner

Speaker 5 of 6
Andrew S. Moore, Howard Hughes Medical Institute, USA
Short Talk: Dynamic Actin Cycling through Mitochondrial Subpopulations Regulates Mitochondrial Network Morphology

Monday, April 04 | 5:00PM - 7:30PM
Mitochondrial Fission and Fusion
Room: Storm Peak/Mt. Werner

Speaker 6 of 6
Henry N. Higgs, Geisel School of Medicine at Dartmouth, USA
Short Talk: Actin Filaments Target the Oligomeric Maturation of Drp1 to Mitochondrial Fission Sites

Monday, April 04 | 7:30PM - 8:30PM
Social Hour with Lite Bites
Room: Foyer/Rainbow/Twilight
No registration fees are used to fund alcohol served at this function.

Monday, April 04 | 7:30PM - 10:00PM
Poster Session 1
Room: Sunshine


Tuesday, April 05 | 7:00AM - 8:00AM
Breakfast
Room: Foyer/Rainbow/Twilight


Tuesday, April 05 | 8:00AM - 11:00AM
Mitochondrial-Organelle Contact Sites
Room: Storm Peak/Mt. Werner

Speaker 1 of 5
William A. Prinz, NIDDK, National Institutes of Health, USA
Lipid Transport to Mitochondria at Membrane Contact Sites

Tuesday, April 05 | 8:00AM - 11:00AM
Mitochondrial-Organelle Contact Sites
Room: Storm Peak/Mt. Werner

Speaker 2 of 5
György Hajnóczky, Thomas Jefferson University, USA
Trafficking of Calcium and ROS between Mitochondria and ER

Tuesday, April 05 | 8:00AM - 11:00AM
Mitochondrial-Organelle Contact Sites
Room: Storm Peak/Mt. Werner

Speaker 3 of 5
* Gia K. Voeltz, University of Colorado Boulder, USA
Multiple Dynamin Family Members Collaborate to Drive Mitochondrial Division

Tuesday, April 05 | 8:00AM - 11:00AM
Mitochondrial-Organelle Contact Sites
Room: Storm Peak/Mt. Werner

Speaker 4 of 5
Maya B. Schuldiner, Weizmann Institute of Science, Israel
Mapping Mitochondrial Contact Sites with Diverse Cellular Organelles

Tuesday, April 05 | 8:00AM - 11:00AM
Mitochondrial-Organelle Contact Sites
Room: Storm Peak/Mt. Werner

Speaker 5 of 5
Alyssa Litwiller, University of Utah, USA
Short Talk: Identification of Machinery Required for Formation of Mitochondrial-Derived Compartments

Tuesday, April 05 | 9:20AM - 9:40AM
Coffee Break
Room: Foyer


Tuesday, April 05 | 11:00AM - 12:00PM
Career Mentoring: Navigating Your Academic or Biotech Career
Room: Storm Peak/Mt. Werner

Speaker 1 of 4
L. Stirling Churchman, Harvard Medical School, USA

Tuesday, April 05 | 11:00AM - 12:00PM
Career Mentoring: Navigating Your Academic or Biotech Career
Room: Storm Peak/Mt. Werner

Speaker 2 of 4
Adam L. Hughes, University of Utah, USA

Tuesday, April 05 | 11:00AM - 12:00PM
Career Mentoring: Navigating Your Academic or Biotech Career
Room: Storm Peak/Mt. Werner

Speaker 3 of 4
Ana J. García-Sáez, University of Tübingen, Germany

Tuesday, April 05 | 11:00AM - 12:00PM
Career Mentoring: Navigating Your Academic or Biotech Career
Room: Storm Peak/Mt. Werner

Speaker 4 of 4
Bruce M. Spiegelman, Harvard Medical School, USA

Tuesday, April 05 | 11:00AM - 5:00PM
On Own for Lunch


Tuesday, April 05 | 11:00AM - 1:00PM
Poster Setup
Room: Sunshine


Tuesday, April 05 | 1:00PM - 10:00PM
Poster Viewing
Room: Sunshine


Tuesday, April 05 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Tuesday, April 05 | 5:00PM - 7:00PM
Mitochondrial Motility
Room: Storm Peak/Mt. Werner

Speaker 1 of 4
Thomas L. Schwarz, Children's Hospital Boston and Harvard Medical School, USA
Mitochondria, Motors and Mitosis

Tuesday, April 05 | 5:00PM - 7:00PM
Mitochondrial Motility
Room: Storm Peak/Mt. Werner

Speaker 2 of 4
* Benedikt Westermann, Universität Bayreuth, Germany
Mitochondrial Motility and Inheritance in Yeast

Tuesday, April 05 | 5:00PM - 7:00PM
Mitochondrial Motility
Room: Storm Peak/Mt. Werner

Speaker 3 of 4
Robert S. Balaban, NHLBI, National Institutes of Health, USA
The Mitochondria Reticulum of Muscle Cells

Tuesday, April 05 | 5:00PM - 7:00PM
Mitochondrial Motility
Room: Storm Peak/Mt. Werner

Speaker 4 of 4
Brian Cunniff, Harvard Medical School, USA
Short Talk: Miro1-Mediated Mitochondrial Distribution Contributes to Focal Adhesion Size, Membrane Protrusion and Cell Migration

Tuesday, April 05 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Foyer/Rainbow/Twilight
No registration fees are used to fund alcohol served at this function.

Tuesday, April 05 | 7:30PM - 10:00PM
Poster Session 2
Room: Sunshine


Wednesday, April 06 | 7:00AM - 8:00AM
Breakfast
Room: Foyer/Rainbow/Twilight


Wednesday, April 06 | 8:00AM - 11:00AM
Mitochondria Biogenesis in Health and Disease
Room: Storm Peak/Mt. Werner

Speaker 1 of 5
David C. Chan, California Institute of Technology, USA
Regulation of Mitochondrial Dynamics

Wednesday, April 06 | 8:00AM - 11:00AM
Mitochondria Biogenesis in Health and Disease
Room: Storm Peak/Mt. Werner

Speaker 2 of 5
* Andrew G. Dillin, University of California, Berkeley, USA
Mitochondria and Protein Folding and Aging

Wednesday, April 06 | 8:00AM - 11:00AM
Mitochondria Biogenesis in Health and Disease
Room: Storm Peak/Mt. Werner

Speaker 3 of 5
Orian S. Shirihai, University of California, Los Angeles, USA
Nutrient Interaction with the Mitochondrial Motility Apparatus Regulate Mitochondrial Dynamics

Wednesday, April 06 | 8:00AM - 11:00AM
Mitochondria Biogenesis in Health and Disease
Room: Storm Peak/Mt. Werner

Speaker 4 of 5
Giovanni Manfredi, Weill Medical College of Cornell University, USA
Mitochondrial Involvement in Amyotrophic Lateral Sclerosis

Wednesday, April 06 | 8:00AM - 11:00AM
Mitochondria Biogenesis in Health and Disease
Room: Storm Peak/Mt. Werner

Speaker 5 of 5
L. Stirling Churchman, Harvard Medical School, USA
Short Talk: Synchronized Translation Programs across Cellular Compartments during Mitochondrial Biogenesis

Wednesday, April 06 | 9:20AM - 9:40AM
Coffee Break
Room: Foyer


Wednesday, April 06 | 11:00AM - 12:00PM
Meet the Editors
Room: Storm Peak/Mt. Werner

Speaker 1 of 7
* Jodi Nunnari, University of California, Davis, USA

Wednesday, April 06 | 11:00AM - 12:00PM
Meet the Editors
Room: Storm Peak/Mt. Werner

Speaker 2 of 7
Nancy R. Gough, National Breast Cancer Coalition, USA

Wednesday, April 06 | 11:00AM - 12:00PM
Meet the Editors
Room: Storm Peak/Mt. Werner

Speaker 3 of 7
Alexia-Ileana Zaromytidou, Nature Cancer, USA

Wednesday, April 06 | 11:00AM - 12:00PM
Meet the Editors
Room: Storm Peak/Mt. Werner

Speaker 4 of 7
Petra Gross, Journal of Cell Science, UK

Wednesday, April 06 | 11:00AM - 12:00PM
Meet the Editors
Room: Storm Peak/Mt. Werner

Speaker 5 of 7
Andrea Leibfried, EMBO Journal, Germany

Wednesday, April 06 | 11:00AM - 12:00PM
Meet the Editors
Room: Storm Peak/Mt. Werner

Speaker 6 of 7
Sadaf Shadan, Nature, UK

Wednesday, April 06 | 11:00AM - 12:00PM
Meet the Editors
Room: Storm Peak/Mt. Werner

Speaker 7 of 7
Nick Fulcher, Nature Protocols, UK

Wednesday, April 06 | 11:00AM - 5:00PM
On Own for Lunch


Wednesday, April 06 | 11:00AM - 1:00PM
Poster Setup
Room: Sunshine


Wednesday, April 06 | 1:00PM - 10:00PM
Poster Viewing
Room: Sunshine


Wednesday, April 06 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Wednesday, April 06 | 5:00PM - 7:15PM
Mitochondria as Signaling Platforms
Room: Storm Peak/Mt. Werner

Speaker 1 of 5
Nika N. Danial, Dana-Farber Cancer Institute, USA
Mitochondria and Energy Metabolism in Disease States

Wednesday, April 06 | 5:00PM - 7:15PM
Mitochondria as Signaling Platforms
Room: Storm Peak/Mt. Werner

Speaker 2 of 5
* Heidi M. McBride, McGill University, Canada
A Role of Mitochondria in Peroxisomal Biogenesis

Wednesday, April 06 | 5:00PM - 7:15PM
Mitochondria as Signaling Platforms
Room: Storm Peak/Mt. Werner

Speaker 3 of 5
Sebastien Herzig, The Salk Institute for Biological Studies, USA

Wednesday, April 06 | 5:00PM - 7:15PM
Mitochondria as Signaling Platforms
Room: Storm Peak/Mt. Werner

Speaker 4 of 5
Hilla Weidberg, University of British Columbia, Canada
Short Talk: A Surprising Role for the Multidrug Resistance Response During Mitochondrial Protein Import Stress

Wednesday, April 06 | 5:00PM - 7:15PM
Mitochondria as Signaling Platforms
Room: Storm Peak/Mt. Werner

Speaker 5 of 5
Heather Weir, Harvard T. H. Chan School of Public Health, USA
Short Talk: Mitochondrial Plasticity is Required for AMPK-Mediated Longevity

Wednesday, April 06 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Foyer/Rainbow/Twilight
No registration fees are used to fund alcohol served at this function.

Wednesday, April 06 | 7:30PM - 10:00PM
Poster Session 3
Room: Sunshine


Thursday, April 07 | 7:00AM - 8:00AM
Breakfast
Room: Foyer/Rainbow/Twilight


Thursday, April 07 | 8:00AM - 11:00AM
Mitochondrial Regulation and Cell Death
Room: Storm Peak/Mt. Werner

Speaker 1 of 5
Ana J. García-Sáez, University of Tübingen, Germany
Mitochondrial Permeabilization by Bax at the Single Molecule Level

Thursday, April 07 | 8:00AM - 11:00AM
Mitochondrial Regulation and Cell Death
Room: Storm Peak/Mt. Werner

Speaker 2 of 5
Siegfried Hekimi, McGill University, Canada
No Evidence that Mitochondrial Dysfunction Causes Animal Aging

Thursday, April 07 | 8:00AM - 11:00AM
Mitochondrial Regulation and Cell Death
Room: Storm Peak/Mt. Werner

Speaker 3 of 5
* Stefan Jakobs, Max Planck Institute for Biophysical Chemistry, Germany
Super-Resolution Microscopy of Bax-Mediated MOMP

Thursday, April 07 | 8:00AM - 11:00AM
Mitochondrial Regulation and Cell Death
Room: Storm Peak/Mt. Werner

Speaker 4 of 5
Suzanne Hoppins, University of Washington, USA
Bax and Mitochondrial Dynamics

Thursday, April 07 | 8:00AM - 11:00AM
Mitochondrial Regulation and Cell Death
Room: Storm Peak/Mt. Werner

Speaker 5 of 5
Isabella Straub, Montreal Neurological Institute-McGill University, Canada
Short Talk: The Role of the Mitochondrial Protein CHCHD10 in Neurodegenerative Disorders

Thursday, April 07 | 9:20AM - 9:40AM
Coffee Break
Room: Foyer


Thursday, April 07 | 11:00AM - 5:00PM
On Own for Lunch


Thursday, April 07 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Thursday, April 07 | 5:00PM - 7:00PM
Mitochondrial Quality Control
Room: Storm Peak/Mt. Werner

Speaker 1 of 4
Richard J. Youle, NINDS, National Institutes of Health, USA
Ubiquitin Signals on Mitochondria Promote Mitophagy via Autophagy Receptors

Thursday, April 07 | 5:00PM - 7:00PM
Mitochondrial Quality Control
Room: Storm Peak/Mt. Werner

Speaker 2 of 4
* Anu Suomalainen Wartiovaara, University of Helsinki, Finland
Neural Pathophysiology upon Mitochondrial Disease

Thursday, April 07 | 5:00PM - 7:00PM
Mitochondrial Quality Control
Room: Storm Peak/Mt. Werner

Speaker 3 of 4
Hong Xu, NHLBI, National Institutes of Health, USA
Translational Regulation of mtDNA Replication and Selection during Drosophila Oogenesis

Thursday, April 07 | 5:00PM - 7:00PM
Mitochondrial Quality Control
Room: Storm Peak/Mt. Werner

Speaker 4 of 4
Marta Vranas, McGill University, Canada
Short Talk: The Structural Basis for Parkin-Mediated Mitochondrial Quality Control

Thursday, April 07 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Storm Peak/Mt. Werner


Thursday, April 07 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Foyer/Rainbow/Twilight
No registration fees are used to fund alcohol served at this function.

Thursday, April 07 | 8:00PM - 11:00PM
Entertainment
Room: Sunshine
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, April 07 | 8:00PM - 11:00PM
Cash Bar
Room: Sunshine


Friday, April 08 | 10:25AM - 10:25AM
Departure


*Session Chair.