Web Desc
Myeloid Cells
Organizer(s): Arturo Zychlinsky, Judith E. Allen, Eicke Latz and Kate A. Fitzgerald
Date: April 10 - 14, 2016
Location: INEC Killarney Convention Centre, Killarney, Co. Kerry, Ireland
Local Co-Organizer: Andrew G. Bowie of Trinity Biomedical Sciences Institute. Organized in Collaboration with Science Foundation Ireland. Sponsored by Biogen
For important information on the coronavirus, please click here
Summary of Meeting:
Myeloid cells are essential in immunity: they control the interaction of the host with the environment and are indispensable in fighting infections and in the communication with other branches of the immune system. The introduction of new technology is revealing unprecedented levels of complexity in ontogeny, specialization, regulation and modulation of adaptive immunity by these cells. This Keystone Symposia meeting will cover topical questions in myeloid cell biology, including new concepts like the origin of myelocytes, trained immunity, and epigenetic and genetic regulation of their function. It will cover myeloid cells of both bone marrow and fetal origin with an emphasis on how macrophages interact with other myeloid cells including granulocytes. There will also be an emphasis on clinical approaches including medical intervention. New approaches to understand the diversity and specificity of myeloid responses will be also included. The symposium will include different fields central to contemporary immunology both at the genetic and cellular level, including the instruction of the adaptive immune response by innate immunity in health and disease. It should therefore be of interest to both basic and clinical scientists working in cell biology, immunology and infectious disease.
Scholarship Deadline: December 10 2015
Discounted Abstract Deadline: December 10 2015
Abstract Deadline: January 11 2016
Discounted Registration Deadline: February 10 2016
Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.


Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
BiogenScience Foundation Ireland
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI122342-01
Funding for this conference was made possible [in part] by 1 R13 AI 122342 - 01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, April 10 | 4:00PM - 8:00PM
Arrival and Registration
Room: Foyer


Sunday, April 10 | 6:00PM - 8:00PM
Welcome Mixer
Room: Foyer
No registration fees are used to fund alcohol served at this function.

Monday, April 11 | 7:30AM - 8:30AM
Breakfast
Room: Foyer


Monday, April 11 | 8:30AM - 8:45AM
Welcoming Remarks
Room: INEC Main Auditorium

Speaker 1 of 1
* Judith E. Allen, University of Manchester, UK

Monday, April 11 | 8:45AM - 9:45AM
Keynote Address
Room: INEC Main Auditorium

Speaker 1 of 2
* Dana Philpott, University of Toronto, Canada

Monday, April 11 | 8:45AM - 9:45AM
Keynote Address
Room: INEC Main Auditorium

Speaker 2 of 2
Douglas Golenbock, University of Massachusetts Medical School, USA
NLRP3 Inflammasome, Alzheimer's and Death: IL18 as an Antidote for IL1-Beta

Monday, April 11 | 9:45AM - 12:30PM
Origins and Diversity
Room: INEC Main Auditorium

Speaker 1 of 5
* Carla V. Rothlin, Yale University, USA

Monday, April 11 | 9:45AM - 12:30PM
Origins and Diversity
Room: INEC Main Auditorium

Speaker 2 of 5
Filip K. Swirski, Massachusetts General Hospital, USA
Monocyte and Macrophage Heterogeneity

Monday, April 11 | 9:45AM - 12:30PM
Origins and Diversity
Room: INEC Main Auditorium

Speaker 3 of 5
Martin Guilliams, Ghent University - VIB, Belgium
Yolk Sac Macrophages, Fetal Liver Monocytes and Adult Monocytes can all Efficiently Colonize an Empty Niche and Develop into Functional Tissue Resident Macrophages

Monday, April 11 | 9:45AM - 12:30PM
Origins and Diversity
Room: INEC Main Auditorium

Speaker 4 of 5
Maria Rescigno, Humanitas University, Italy
Dendritic Cells in the Gut

Monday, April 11 | 9:45AM - 12:30PM
Origins and Diversity
Room: INEC Main Auditorium

Speaker 5 of 5
Steffen Jung, Weizmann Institute of Science, Israel
Development and Tissue Specialisation of Macrophages

Monday, April 11 | 10:20AM - 10:40AM
Coffee Break
Room: Foyer


Monday, April 11 | 12:30PM - 5:00PM
On Own for Lunch


Monday, April 11 | 12:30PM - 1:00PM
Poster Setup
Room: Foyer


Monday, April 11 | 1:00PM - 10:00PM
Poster Viewing
Room: Foyer


Monday, April 11 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Monday, April 11 | 5:00PM - 7:15PM
Taming Inflammation
Room: INEC Main Auditorium

Speaker 1 of 6
* Irina A. Udalova, University of Oxford, UK

Monday, April 11 | 5:00PM - 7:15PM
Taming Inflammation
Room: INEC Main Auditorium

Speaker 2 of 6
Dana Philpott, University of Toronto, Canada
NLRs in Infection

Monday, April 11 | 5:00PM - 7:15PM
Taming Inflammation
Room: INEC Main Auditorium

Speaker 3 of 6
Arturo Zychlinsky, Max Planck Institute for Infection Biology, Germany
Inflammatory Neutrophil Mechanisms

Monday, April 11 | 5:00PM - 7:15PM
Taming Inflammation
Room: INEC Main Auditorium

Speaker 4 of 6
Kathryn J. Moore, New York University Medical Center, USA
MicroRNA Regulation of Macrophage Metabolism and Immune Response

Monday, April 11 | 5:00PM - 7:15PM
Taming Inflammation
Room: INEC Main Auditorium

Speaker 5 of 6
Basak B. Cicek, University of Connecticut Health Center, USA
Short Talk: Discovery of a Novel Subset of Lung Resident Macrophages that Regulate Pathogen Clearance and Immune Homeostasis during Respiratory Infection

Monday, April 11 | 5:00PM - 7:15PM
Taming Inflammation
Room: INEC Main Auditorium

Speaker 6 of 6
Julia Esser-von Bieren, Technical University and Helmholtz Centre Munich, Germany
Short Talk: Age-Dependent Regulation of Remodeling Factors Governs
Myeloid-Epithelial Cell Crosstalk during Airway Inflammation


Monday, April 11 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Foyer
No registration fees are used to fund alcohol served at this function.

Monday, April 11 | 7:30PM - 10:00PM
Poster Session 1
Room: Foyer


Tuesday, April 12 | 7:30AM - 8:30AM
Breakfast
Room: Foyer


Tuesday, April 12 | 8:30AM - 11:45AM
Mechanisms of Differentiation and Activation
Room: INEC Main Auditorium

Speaker 1 of 7
* Kathryn J. Moore, New York University Medical Center, USA

Tuesday, April 12 | 8:30AM - 11:45AM
Mechanisms of Differentiation and Activation
Room: INEC Main Auditorium

Speaker 2 of 7
Sergio Grinstein, Hospital for Sick Children, Canada
Integrins Form an Expanding Diffusion Barrier that Enables Src-Family Kinase Activation during Phagocytosis.

Tuesday, April 12 | 8:30AM - 11:45AM
Mechanisms of Differentiation and Activation
Room: INEC Main Auditorium

Speaker 3 of 7
Seamus J. Martin, Trinity College Dublin, Ireland
Neutrophil Granule Proteases Act as Global Regulators of Extended IL-1 Family Cytokine Activation States

Tuesday, April 12 | 8:30AM - 11:45AM
Mechanisms of Differentiation and Activation
Room: INEC Main Auditorium

Speaker 4 of 7
Kate A. Fitzgerald, University of Massachusetts Medical School, USA
Regulation of Inflammation by Long Noncoding RNAs

Tuesday, April 12 | 8:30AM - 11:45AM
Mechanisms of Differentiation and Activation
Room: INEC Main Auditorium

Speaker 5 of 7
Irina A. Udalova, University of Oxford, UK
IRF5 Controls Acute Inflammation: Cross-Talk of Myeloid Cells

Tuesday, April 12 | 8:30AM - 11:45AM
Mechanisms of Differentiation and Activation
Room: INEC Main Auditorium

Speaker 6 of 7
Helen S. Goodridge, Cedars-Sinai Medical Center, USA
Short Talk: Independent Production of Distinct Monocyte Subsets by Granulocyte-Monocyte Progenitors (GMPs) and Monocyte-Dendritic Cell Progenitors (MDPs)

Tuesday, April 12 | 8:30AM - 11:45AM
Mechanisms of Differentiation and Activation
Room: INEC Main Auditorium

Speaker 7 of 7
Philipp Henneke, University-Medical Center Freiburg, Germany
Short Talk: A Novel Macrophage Subset Instructs Immunity in Staphylococcal Skin Infection

Tuesday, April 12 | 9:50AM - 10:10AM
Coffee Break
Room: Foyer


Tuesday, April 12 | 11:45AM - 5:00PM
On Own for Lunch


Tuesday, April 12 | 11:45AM - 1:00PM
Poster Setup
Room: Foyer


Tuesday, April 12 | 1:00PM - 10:00PM
Poster Viewing
Room: Foyer


Tuesday, April 12 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Tuesday, April 12 | 5:00PM - 7:15PM
Myeloid Cells in Disease Models I
Room: INEC Main Auditorium

Speaker 1 of 6
* Nicola L. Harris, Monash University, Australia

Tuesday, April 12 | 5:00PM - 7:15PM
Myeloid Cells in Disease Models I
Room: INEC Main Auditorium

Speaker 2 of 6
Gretchen E. Diehl, Baylor College of Medicine, USA
Crosstalk between Intestinal Myeloid Cells and the Microbiota Limit Intestinal Inflammation

Tuesday, April 12 | 5:00PM - 7:15PM
Myeloid Cells in Disease Models I
Room: INEC Main Auditorium

Speaker 3 of 6
Judith E. Allen, University of Manchester, UK
Dynamics of Resident vs. Recruited Macrophages

Tuesday, April 12 | 5:00PM - 7:15PM
Myeloid Cells in Disease Models I
Room: INEC Main Auditorium

Speaker 4 of 6
Eicke Latz, University of Bonn, Germany
Inflammasome Activation in Disease

Tuesday, April 12 | 5:00PM - 7:15PM
Myeloid Cells in Disease Models I
Room: INEC Main Auditorium

Speaker 5 of 6
Florent Ginhoux, Singapore Immunology Network, Singapore
Short Talk: Dendritic Cell and Macrophage Ontogeny

Tuesday, April 12 | 5:00PM - 7:15PM
Myeloid Cells in Disease Models I
Room: INEC Main Auditorium

Speaker 6 of 6
Yonit Lavin, Mount Sinai School of Medicine, USA
Short Talk: Multi-Parameter Analysis of Myeloid Cells Allows for Identification of Distinct Populations in the Lung and Tumor of Non-Small Cell Lung Cancer Patients

Tuesday, April 12 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Foyer
No registration fees are used to fund alcohol served at this function.

Tuesday, April 12 | 7:30PM - 10:00PM
Poster Session 2
Room: Foyer


Wednesday, April 13 | 7:30AM - 8:30AM
Breakfast
Room: Foyer


Wednesday, April 13 | 8:30AM - 11:45AM
Myeloid Cells in Disease Models II
Room: INEC Main Auditorium

Speaker 1 of 8
* Adam Lacy-Hulbert, Benaroya Research Institute, USA

Wednesday, April 13 | 8:30AM - 11:45AM
Myeloid Cells in Disease Models II
Room: INEC Main Auditorium

Speaker 2 of 8
* Maria Rescigno, Humanitas University, Italy

Wednesday, April 13 | 8:30AM - 11:45AM
Myeloid Cells in Disease Models II
Room: INEC Main Auditorium

Speaker 3 of 8
Nicola L. Harris, Monash University, Australia
Macrophages in Infection and Repair

Wednesday, April 13 | 8:30AM - 11:45AM
Myeloid Cells in Disease Models II
Room: INEC Main Auditorium

Speaker 4 of 8
P'ng Loke, New York University School of Medicine, USA
Alternatively Activated M2 Macrophages in Helminth Infections

Wednesday, April 13 | 8:30AM - 11:45AM
Myeloid Cells in Disease Models II
Room: INEC Main Auditorium

Speaker 5 of 8
Felix Meissner, Max Planck Institute of Biochemistry, Germany
Quantitative Proteomics of Secreted Proteins Defines How Macrophages Regulate Inflammation

Wednesday, April 13 | 8:30AM - 11:45AM
Myeloid Cells in Disease Models II
Room: INEC Main Auditorium

Speaker 6 of 8
Carla V. Rothlin, Yale University, USA
TAM Receptors in Immunity

Wednesday, April 13 | 8:30AM - 11:45AM
Myeloid Cells in Disease Models II
Room: INEC Main Auditorium

Speaker 7 of 8
Christina Kassiteridi, Oxford University, UK
Short Talk: Myeloid Cell Regulation by CD200 Signalling in Atherosclerosis

Wednesday, April 13 | 8:30AM - 11:45AM
Myeloid Cells in Disease Models II
Room: INEC Main Auditorium

Speaker 8 of 8
Marlene Magalhaes Pinto, University of Edinburgh, Queen's Medical Research Institute, UK
Short Talk: IL-33 Controls the Establishment of Adipose Tissue Macrophage Subsets during Neo-Natal Development

Wednesday, April 13 | 9:50AM - 10:10AM
Coffee Break
Room: Foyer


Wednesday, April 13 | 11:45AM - 5:00PM
On Own for Lunch


Wednesday, April 13 | 11:45AM - 1:00PM
Poster Setup
Room: Foyer


Wednesday, April 13 | 1:00PM - 10:00PM
Poster Viewing
Room: Foyer


Wednesday, April 13 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Wednesday, April 13 | 5:00PM - 7:15PM
Neutrophils
Room: INEC Main Auditorium

Speaker 1 of 6
* Gretchen E. Diehl, Baylor College of Medicine, USA

Wednesday, April 13 | 5:00PM - 7:15PM
Neutrophils
Room: INEC Main Auditorium

Speaker 2 of 6
Lani Wu, University of California, San Francisco, USA
Deciphering Neutrophil Chemotaxis

Wednesday, April 13 | 5:00PM - 7:15PM
Neutrophils
Room: INEC Main Auditorium

Speaker 3 of 6
Christoph Klein, Ludwig-Maximilians-University, Germany
Inborn Errors of Neutrophil Granulocytes

Wednesday, April 13 | 5:00PM - 7:15PM
Neutrophils
Room: INEC Main Auditorium

Speaker 4 of 6
Eric Pearlman, University of California, Irvine, USA
NLRP3 Inflammasome Activation and P2X7R Induced IL-1 beta Secretion by Neutrophils

Wednesday, April 13 | 5:00PM - 7:15PM
Neutrophils
Room: INEC Main Auditorium

Speaker 5 of 6
Regina Clemens, University of California, San Francisco, USA
Short Talk: STIM2-Mediated Store-Operated Calcium Entry Regulates
Neutrophil Cytokine Production


Wednesday, April 13 | 5:00PM - 7:15PM
Neutrophils
Room: INEC Main Auditorium

Speaker 6 of 6
Maria Casanova-Acebes, Mount Sinai School of Medicine, USA

Wednesday, April 13 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Foyer
No registration fees are used to fund alcohol served at this function.

Wednesday, April 13 | 7:30PM - 10:00PM
Poster Session 3
Room: Foyer


Thursday, April 14 | 7:30AM - 8:30AM
Breakfast
Room: Foyer


Thursday, April 14 | 8:30AM - 11:45AM
Trained Immunity
Room: INEC Main Auditorium

Speaker 1 of 7
* Maria Belvisi, Imperial College London, UK

Thursday, April 14 | 8:30AM - 11:45AM
Trained Immunity
Room: INEC Main Auditorium

Speaker 2 of 7
Gioacchino Natoli, Humanitas University, Italy
The Genomic Landscapes of Inflammation

Thursday, April 14 | 8:30AM - 11:45AM
Trained Immunity
Room: INEC Main Auditorium

Speaker 3 of 7
Mihai G. Netea, Radboud University, Netherlands
Trained Immunity: A Memory for the Innate Immune Responses

Thursday, April 14 | 8:30AM - 11:45AM
Trained Immunity
Room: INEC Main Auditorium

Speaker 4 of 7
Joachim L. Schultze, LIMES Institute, University of Bonn, Germany
The Multi-Dimensional Model of Macrophage Activation

Thursday, April 14 | 8:30AM - 11:45AM
Trained Immunity
Room: INEC Main Auditorium

Speaker 5 of 7
Andrew G. Bowie, Trinity College Dublin, Ireland
PYHIN Proteins and Gene Regulation during Innate Immune Responses

Thursday, April 14 | 8:30AM - 11:45AM
Trained Immunity
Room: INEC Main Auditorium

Speaker 6 of 7
Allan McI. Mowat, University of Glasgow, UK
Short Talk: TGFb Drives the Tissue Specific Differentiation of Monocytes into Homeostatic Intestinal Macrophages

Thursday, April 14 | 8:30AM - 11:45AM
Trained Immunity
Room: INEC Main Auditorium

Speaker 7 of 7
Cristina Lopez-Rodriguez, Universitat Pompeu Fabra, Spain
Short Talk: Transcriptional Regulation of Inflammatory Gene Expression

Thursday, April 14 | 9:50AM - 10:10AM
Coffee Break
Room: Foyer


Thursday, April 14 | 11:45AM - 5:00PM
On Own for Lunch


Thursday, April 14 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Thursday, April 14 | 5:00PM - 6:45PM
Myeloid Cells in the Clinic
Room: INEC Main Auditorium

Speaker 1 of 4
* Lani Wu, University of California, San Francisco, USA

Thursday, April 14 | 5:00PM - 6:45PM
Myeloid Cells in the Clinic
Room: INEC Main Auditorium

Speaker 2 of 4
Molly Ingersoll, Institut Pasteur, France
Hormone-mediated Differences in Innate Immune Responses Impact Bacterial Uptake and Clearance in Urinary Tract Infection

Thursday, April 14 | 5:00PM - 6:45PM
Myeloid Cells in the Clinic
Room: INEC Main Auditorium

Speaker 3 of 4
Matthew L. Albert, Genentech, Inc., USA
Systems Approach to Immune Monitoring and Immunotherapy

Thursday, April 14 | 5:00PM - 6:45PM
Myeloid Cells in the Clinic
Room: INEC Main Auditorium

Speaker 4 of 4
Maria Belvisi, Imperial College London, UK
Structural and Myeloid Cell Interactions in Lung Disease

Thursday, April 14 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: INEC Main Auditorium


Thursday, April 14 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Foyer
No registration fees are used to fund alcohol served at this function.

Thursday, April 14 | 7:45PM - 11:00PM
Entertainment
Room: Foyer
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, April 14 | 8:00PM - 11:00PM
Cash Bar
Room: Foyer


Friday, April 15 | 10:23AM - 10:23AM
Departure


*Session Chair
†Invited, not yet responded.