Web Desc
Traumatic Brain Injury: Clinical, Pathological and Translational Mechanisms
joint with Axons: From Cell Biology to Pathology
Organizer(s): Ann C. McKee, Ramon Diaz-Arrastia and Lee E. Goldstein
Date: January 24 - 27, 2016
Location: Eldorado Hotel & Spa, Santa Fe, NM, USA
Supported by the Directors' Fund
Summary of Meeting:
Traumatic brain injury (TBI) is one of the most common human afflictions. Yet until recently the consequences of TBI were either ignored or considered beyond the reach of medical science. Over the past few years, in association with growing societal, governmental and academic recognition of the effects of TBI, particularly in the context of sports-related concussions and military service-related injuries, there have been remarkable advances in clinical and basic neuroscience of TBI. Correspondingly, the field of TBI science has transformed into one of the most dynamic and fertile areas of research. It has also become apparent that TBI is not just a singular disorder, but encompasses single or multiple injuries, of severity ranging from minor to severe, and provokes acute and chronic consequences. It is also increasingly recognized that TBI can trigger latent neurodegenerations with diverse pathologies, such as Chronic Traumatic Encephalopathy (CTE), and in some cases, Alzheimer’s disease (AD) or Parkinson’s disease (PD). This three-day meeting focuses on: 1) What we know about mechanisms and manifestations of traumatic brain injury based on human observational studies; 2) Exploration of molecular mechanisms of injury based on animal models and translational aspects of TBI research; and 3) The development of potential diagnostics and therapeutics.
Scholarship Deadline: September 24 2015
Discounted Abstract Deadline: September 24 2015
Abstract Deadline: October 27 2015
Discounted Registration Deadline: December 18 2015
We gratefully acknowledge additional support for this conference from:
Integra Foundation
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Avid Radiopharmaceuticals, Inc.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
NeuroscientistNews
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, January 24 | 4:00PM - 8:00PM
Arrival and Registration
Room: Eldorado Lounge


Sunday, January 24 | 6:00PM - 8:00PM
Welcome Mixer
Room: Eldorado Lounge
No registration fees are used to fund alcohol served at this function.

Monday, January 25 | 7:00AM - 8:00AM
Breakfast
Room: Anasazi Ballroom


Monday, January 25 | 7:30AM - 8:00AM
Poster Setup
Room: Anasazi Ballroom


Monday, January 25 | 8:00AM - 5:00PM
Poster Viewing
Room: Anasazi Ballroom


Monday, January 25 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Eldorado A

Speaker 1 of 2
* Ann C. McKee, Boston University / VA Boston Healthcare System, USA

Monday, January 25 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Eldorado A

Speaker 2 of 2
Maiken Nedergaard, University of Rochester, USA
The Glymphatic System and its Importance in Amyloid Clearance

Monday, January 25 | 9:00AM - 11:30AM
What Are the Effects of TBI? Evidence from Human Observation
al Studies

Room: Eldorado A

Speaker 1 of 6
* Lee E. Goldstein, Boston University, USA

Monday, January 25 | 9:00AM - 11:30AM
What Are the Effects of TBI? Evidence from Human Observation
al Studies

Room: Eldorado A

Speaker 2 of 6
Ann C. McKee, Boston University / VA Boston Healthcare System, USA
Potential Long-Term Effects of Repetitive Concussive and Subconcussive Trauma

Monday, January 25 | 9:00AM - 11:30AM
What Are the Effects of TBI? Evidence from Human Observation
al Studies

Room: Eldorado A

Speaker 3 of 6
Alon Friedman, Ben-Gurion University of the Negev, Israel
Blood-Brain Barrier Dysfunction as a Biomarker and Target for Treatment in Brain Injuries

Monday, January 25 | 9:00AM - 11:30AM
What Are the Effects of TBI? Evidence from Human Observation
al Studies

Room: Eldorado A

Speaker 4 of 6
Alan Pearce, University of Melbourne, Australia
Using Transcranial Magnetic Stimulation to Measure Neurophysiological Responses Following Concussion

Monday, January 25 | 9:00AM - 11:30AM
What Are the Effects of TBI? Evidence from Human Observation
al Studies

Room: Eldorado A

Speaker 5 of 6
Jillian Urban, Wake Forest University, USA
Short Talk: Cumulative Head Impact Exposure in Youth Football Players

Monday, January 25 | 9:00AM - 11:30AM
What Are the Effects of TBI? Evidence from Human Observation
al Studies

Room: Eldorado A

Speaker 6 of 6
Daniel Daneshvar, Boston University, USA
Short Talk: Examining Repetitive Head Impact Exposure Metrics and Risk of Chronic Traumatic Encephalopathy in American Football Players

Monday, January 25 | 9:00AM - 11:15AM
Axon Cytoskeleton and Specification
This session is from Axons
Room: Eldorado B

Speaker 1 of 5
Melissa Rolls, Pennsylvania State University, USA
Using Live Imaging of Dynamic Microtubules to Understand Axon Injury Responses


Monday, January 25 | 9:00AM - 11:15AM
Axon Cytoskeleton and Specification
This session is from Axons
Room: Eldorado B

Speaker 2 of 5
Erik Dent, University of Wisconsin-Madison, USA
Role of an F-BAR Protein in Inhibiting Axon Outgrowth


Monday, January 25 | 9:00AM - 11:15AM
Axon Cytoskeleton and Specification
This session is from Axons
Room: Eldorado B

Speaker 3 of 5
Francisca C. Bronfman, Catholic University, Chile
Short Talk: Axonal BDNF Promotes Local Axonal Synthesis and Retrograde Transport of the Transcription Factor PPARgamma in an mTOR-Dependent Manner


Monday, January 25 | 9:00AM - 11:15AM
Axon Cytoskeleton and Specification
This session is from Axons
Room: Eldorado B

Speaker 4 of 5
Christopher V. Gabel, Boston University School of Medicine, USA
Short Talk: The What, Where, and When of Activity Induced Calcium Signaling in Neuronal Regeneration


Monday, January 25 | 9:00AM - 11:15AM
Axon Cytoskeleton and Specification
This session is from Axons
Room: Eldorado B

Speaker 5 of 5
Jing Jin, Institute of Molecular Cell Biology, Germany
Short Talk: Ndr1/2 Kinases Regulate Neuronal Polarity through the Regulation of Par3


Monday, January 25 | 9:40AM - 10:00AM
Coffee Break
Room: Concourse


Monday, January 25 | 11:30AM - 12:15PM
Lunch
Room: Anasazi Ballroom


Monday, January 25 | 12:00PM - 2:30PM
Poster Session 1
Room: Anasazi Ballroom


Monday, January 25 | 2:30PM - 4:30PM
Workshop 1: TBI, Neuroinflammation and Microvasculopathy
Room: Eldorado A

Speaker 1 of 7
* Maiken Nedergaard, University of Rochester, USA

Monday, January 25 | 2:30PM - 4:30PM
Workshop 1: TBI, Neuroinflammation and Microvasculopathy
Room: Eldorado A

Speaker 2 of 7
Rita H. Nguyen, University of Calgary, Canada
Understanding the Role of Microglia Following Repetitive Mild Traumatic Brain Injury using Intravital Microscopy

Monday, January 25 | 2:30PM - 4:30PM
Workshop 1: TBI, Neuroinflammation and Microvasculopathy
Room: Eldorado A

Speaker 3 of 7
Jon D. Cherry, Boston University School of Medicine, USA
Repetitive Head Injury Results in Neuroinflammation that Precedes Chronic Traumatic Encephalopathy Pathology and Scales with Disease Severity

Monday, January 25 | 2:30PM - 4:30PM
Workshop 1: TBI, Neuroinflammation and Microvasculopathy
Room: Eldorado A

Speaker 4 of 7
Barry W. Festoff, University of Kansas Medical School, Phlogistix LLC, USA
TBI Effects on BBB Neuro-Gliovascular (N-GVU) Units Modeled by Inflammo-Coag Factors In Vitro

Monday, January 25 | 2:30PM - 4:30PM
Workshop 1: TBI, Neuroinflammation and Microvasculopathy
Room: Eldorado A

Speaker 5 of 7
Susanna Rosi, University of California, San Francisco, USA
In vivo Metabolic Imaging of Neuroinflammation after TBI

Monday, January 25 | 2:30PM - 4:30PM
Workshop 1: TBI, Neuroinflammation and Microvasculopathy
Room: Eldorado A

Speaker 6 of 7
Bertrand Russell Huber, VA Boston Healthcare, USA
Assessing Long-Term Vascular Dysfunction in Chronic Traumatic Encephalopathy with Fibrinogen Immunohistochemistry

Monday, January 25 | 2:30PM - 4:30PM
Workshop 1: TBI, Neuroinflammation and Microvasculopathy
Room: Eldorado A

Speaker 7 of 7
Dara Bree, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Novel Characterisation of Headache-Related Behaviours in a Clinically Relevant Rat Model of Posttraumatic Headache

Monday, January 25 | 2:30PM - 4:30PM
Axonal Degeneration and Regeneration
This session is from Axons
Room: Eldorado B

Speaker 1 of 5
* Valeria Cavalli, Washington University, USA


Monday, January 25 | 2:30PM - 4:30PM
Axonal Degeneration and Regeneration
This session is from Axons
Room: Eldorado B

Speaker 2 of 5
Marc Hammarlund, Yale University School of Medicine, USA
Neuronal Regulation of Axon Regeneration


Monday, January 25 | 2:30PM - 4:30PM
Axonal Degeneration and Regeneration
This session is from Axons
Room: Eldorado B

Speaker 3 of 5
Trent A. Watkins, Baylor College of Medicine, USA
DLK-Dependent Regulation of the Degenerative and Regenerative Responses to Axonal Injury


Monday, January 25 | 2:30PM - 4:30PM
Axonal Degeneration and Regeneration
This session is from Axons
Room: Eldorado B

Speaker 4 of 5
Richard E. Zigmond, Case Western Reserve University, USA
Macrophages in Dorsal Root Ganglia (drgs) Promote Nerve Regeneration through a Stat3-Dependent Mechanism


Monday, January 25 | 2:30PM - 4:30PM
Axonal Degeneration and Regeneration
This session is from Axons
Room: Eldorado B

Speaker 5 of 5
Peter Walter, HHMI/University of California, San Francisco, USA
Inhibition of the Integrated Stress Response Restores Cognition After Brain Injury


Monday, January 25 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Monday, January 25 | 5:00PM - 7:00PM
What Are the Effects of TBI? Evidence from Neuroimaging Stud
ies

Room: Eldorado A

Speaker 1 of 4
* Alon Friedman, Ben-Gurion University of the Negev, Israel

Monday, January 25 | 5:00PM - 7:00PM
What Are the Effects of TBI? Evidence from Neuroimaging Stud
ies

Room: Eldorado A

Speaker 2 of 4
Jeffrey J. Bazarian, University of Rochester Medical Center, USA
DTI Coupled with Helmet Impact Sensors Provides Insight into the Relationship between Repetitive Head Hits and Traumatic Axonal Injury

Monday, January 25 | 5:00PM - 7:00PM
What Are the Effects of TBI? Evidence from Neuroimaging Stud
ies

Room: Eldorado A

Speaker 3 of 4
Rami Burstein, Harvard Medical School, USA
The Pathophysiology of Trauma Induced Headache

Monday, January 25 | 5:00PM - 7:00PM
What Are the Effects of TBI? Evidence from Neuroimaging Stud
ies

Room: Eldorado A

Speaker 4 of 4
Ramon Diaz-Arrastia, Uniformed Services University of the Health Sciences, USA
Overview of Neuroimaging

Monday, January 25 | 5:00PM - 7:00PM
RNA Targeting and Local Translation
This session is from Axons
Room: Eldorado B

Speaker 1 of 6
* Michael Fainzilber, Weizmann Institute of Science, Israel


Monday, January 25 | 5:00PM - 7:00PM
RNA Targeting and Local Translation
This session is from Axons
Room: Eldorado B

Speaker 2 of 6
* Christopher V. Gabel, Boston University School of Medicine, USA


Monday, January 25 | 5:00PM - 7:00PM
RNA Targeting and Local Translation
This session is from Axons
Room: Eldorado B

Speaker 3 of 6
Jeffery L. Twiss, University of South Carolina, USA
Molecular Determinants for mRNA Transport into Axons


Monday, January 25 | 5:00PM - 7:00PM
RNA Targeting and Local Translation
This session is from Axons
Room: Eldorado B

Speaker 4 of 6
Dianna E. Willis, Burke-Cornell Medical Research Institute, USA
Altered RNA Binding Protein Regulation and Axonal RNA Transport in Diabetic Peripheral Neuropathy


Monday, January 25 | 5:00PM - 7:00PM
RNA Targeting and Local Translation
This session is from Axons
Room: Eldorado B

Speaker 5 of 6
Ulrich Hengst, Columbia University, USA
Short Talk: Regulation of Retrograde Transport in Axons through Local Synthesis of Dynein Adaptor Proteins


Monday, January 25 | 5:00PM - 7:00PM
RNA Targeting and Local Translation
This session is from Axons
Room: Eldorado B

Speaker 6 of 6
Alexander Jaworski, Brown University, USA
Short Talk: Operational Redundancy in Axon Guidance through the Multifunctional Receptor Robo3 and its Ligand NELL2


Monday, January 25 | 7:00PM - 7:00PM
On Own for Dinner


Monday, January 25 | 8:00PM - 10:00PM
OPTIONAL - Poster Session for Down Syndrome
Room: Hilton Santa Fe - Mesa C


Tuesday, January 26 | 7:00AM - 8:00AM
Breakfast
Room: Anasazi Ballroom


Tuesday, January 26 | 8:00AM - 11:00AM
Mechanistic Insights from Animal Studies
Room: Eldorado A

Speaker 1 of 6
* John M. Lee, North Shore University Health System, USA

Tuesday, January 26 | 8:00AM - 11:00AM
Mechanistic Insights from Animal Studies
Room: Eldorado A

Speaker 2 of 6
Lee E. Goldstein, Boston University, USA
Acute and Chronic Neuronal Injury: Insights from Murine Models of Blast and Impact TBI

Tuesday, January 26 | 8:00AM - 11:00AM
Mechanistic Insights from Animal Studies
Room: Eldorado A

Speaker 3 of 6
Matt Russo, National Institutes of Health, USA
Short Talk: Role of Resident vs. Peripherally-Derived Myeloid Cells in the Immune Response to Mild Traumatic Brain Injury

Tuesday, January 26 | 8:00AM - 11:00AM
Mechanistic Insights from Animal Studies
Room: Eldorado A

Speaker 4 of 6
Karen Duff, Columbia University, USA
Propagation of Tau Pathology: Lessons Learned from Neurodegenerative Diseases

Tuesday, January 26 | 8:00AM - 11:00AM
Mechanistic Insights from Animal Studies
Room: Eldorado A

Speaker 5 of 6
Andrew Fisher, Boston University, USA
Short Talk: Comparative Modeling of Blast- and Impact-Induced Traumatic Brain Injury

Tuesday, January 26 | 8:00AM - 11:00AM
Mechanistic Insights from Animal Studies
Room: Eldorado A

Speaker 6 of 6
Mark Walter Wojnarowicz, Boston University, USA
Short Talk: Microvasculopathy, Blood-Brain Barrier Dysfunction, and Early Chronic Traumatic Encephalopathy-Linked Neuropathology In a Mouse Model of Concussive Impact Neurotrauma

Tuesday, January 26 | 8:00AM - 11:15AM
Axonal Signaling Mechanisms
This session is from Axons
Room: Eldorado B

Speaker 1 of 8
* Marc Hammarlund, Yale University School of Medicine, USA


Tuesday, January 26 | 8:00AM - 11:15AM
Axonal Signaling Mechanisms
This session is from Axons
Room: Eldorado B

Speaker 2 of 8
* Alexander Jaworski, Brown University, USA


Tuesday, January 26 | 8:00AM - 11:15AM
Axonal Signaling Mechanisms
This session is from Axons
Room: Eldorado B

Speaker 3 of 8
Steven J. Burden, New York University Medical Center, USA
Bi-Directional Signaling to Form and Preserve Neuromuscular Synapses


Tuesday, January 26 | 8:00AM - 11:15AM
Axonal Signaling Mechanisms
This session is from Axons
Room: Eldorado B

Speaker 4 of 8
Michael Fainzilber, Weizmann Institute of Science, Israel
From Retrograde Injury Signaling to Axon Growth Control


Tuesday, January 26 | 8:00AM - 11:15AM
Axonal Signaling Mechanisms
This session is from Axons
Room: Eldorado B

Speaker 5 of 8
Valeria Cavalli, Washington University, USA
Activating a Regeneration Program with Hypoxia


Tuesday, January 26 | 8:00AM - 11:15AM
Axonal Signaling Mechanisms
This session is from Axons
Room: Eldorado B

Speaker 6 of 8
Bruce D. Carter, Vanderbilt University School of Medicine, USA
Mechanisms of Retrograde Apoptotic Signaling by the p75 Neurotrophin Receptor


Tuesday, January 26 | 8:00AM - 11:15AM
Axonal Signaling Mechanisms
This session is from Axons
Room: Eldorado B

Speaker 7 of 8
Eva Klinman, University of Pennsylvania, USA
Short Talk: Regulation of Neuronal Trafficking and Transport by CDK5


Tuesday, January 26 | 8:00AM - 11:15AM
Axonal Signaling Mechanisms
This session is from Axons
Room: Eldorado B

Speaker 8 of 8
Patti Murphy, University of Pennsylvania, USA
Short Talk: Roundabout2 and Exotosin-like 3 Promote Target Specific Peripheral Nerve Regeneration in vivo


Tuesday, January 26 | 9:20AM - 9:40AM
Coffee Break
Room: Concourse


Tuesday, January 26 | 11:00AM - 1:00PM
Poster Setup
Room: Anasazi Ballroom


Tuesday, January 26 | 11:00AM - 12:30PM
On Own for Lunch


Tuesday, January 26 | 12:30PM - 2:30PM
OPTIONAL - Poster Session for Down Syndrome
Room: Hilton Santa Fe - Mesa C


Tuesday, January 26 | 1:00PM - 10:00PM
Poster Viewing
Room: Anasazi Ballroom


Tuesday, January 26 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Tuesday, January 26 | 5:00PM - 7:00PM
Mechanistic Insights from Human Studies
Room: Eldorado A

Speaker 1 of 6
* Lee E. Goldstein, Boston University, USA

Tuesday, January 26 | 5:00PM - 7:00PM
Mechanistic Insights from Human Studies
Room: Eldorado A

Speaker 2 of 6
T. Blaine Hoshizaki, University of Ottawa, Canada
The Relationship between Impact Characteristics and Brain Tissue Strain Distributions

Tuesday, January 26 | 5:00PM - 7:00PM
Mechanistic Insights from Human Studies
Room: Eldorado A

Speaker 3 of 6
Susan Margulies, University of Pennsylvania, USA
Mechanisms of Pediatric TBI - Integrating Human and Animal Studies

Tuesday, January 26 | 5:00PM - 7:00PM
Mechanistic Insights from Human Studies
Room: Eldorado A

Speaker 4 of 6
Tsang-Wei Tu, National Institutes of Health, USA
Short Talk: GlucoCEST Correlates with 2DG Autoradiography in Monitoring Glucose Metabolism in Mild Traumatic Brain Injury

Tuesday, January 26 | 5:00PM - 7:00PM
Mechanistic Insights from Human Studies
Room: Eldorado A

Speaker 5 of 6
Ramon Diaz-Arrastia, Uniformed Services University of the Health Sciences, USA
Short Talk: DTI and MAP-MRI Abnormalities in the Closed Head Injury Model of Engineered Rotational Acceleration (CHIMERA) Mouse Model of Diffuse Axonal Injury

Tuesday, January 26 | 5:00PM - 7:00PM
Mechanistic Insights from Human Studies
Room: Eldorado A

Speaker 6 of 6
Cheryl Wellington, University of British Columbia, Canada
Short Talk: Traumatic Brain Injury and Steroids

Tuesday, January 26 | 5:00PM - 7:15PM
Axonal Membrane Dynamics and Axonal Transport
This session is from Axons
Room: Eldorado B

Speaker 1 of 5
* Subhojit Roy, University of Wisconsin Madison, USA


Tuesday, January 26 | 5:00PM - 7:15PM
Axonal Membrane Dynamics and Axonal Transport
This session is from Axons
Room: Eldorado B

Speaker 2 of 5
Yoshio Goshima, Yokohama City University Graduate School of Medicine, Japan
Axonal Transport Elicited by Axon Guidance Molecules


Tuesday, January 26 | 5:00PM - 7:15PM
Axonal Membrane Dynamics and Axonal Transport
This session is from Axons
Room: Eldorado B

Speaker 3 of 5
Rejji Kuruvilla, Johns Hopkins University, USA
Endocytic Trafficking of Neurotrophins in Neural Development



Tuesday, January 26 | 5:00PM - 7:15PM
Axonal Membrane Dynamics and Axonal Transport
This session is from Axons
Room: Eldorado B

Speaker 4 of 5
Casper Hoogenraad, Genentech, Inc., USA
Mechanisms of Axon Formation: Microtubule Remodeling and Motor Activity


Tuesday, January 26 | 5:00PM - 7:15PM
Axonal Membrane Dynamics and Axonal Transport
This session is from Axons
Room: Eldorado B

Speaker 5 of 5
Karen Duff, Columbia University, USA
Tau Proteinopathy, Neuronal Dyshomeostasis and Neurodegeneration


Tuesday, January 26 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Anasazi Ballroom
No registration fees are used to fund alcohol served at this function.

Tuesday, January 26 | 7:30PM - 10:00PM
Poster Session 2
Room: Anasazi Ballroom


Wednesday, January 27 | 7:00AM - 8:00AM
Breakfast
Room: Anasazi Ballroom


Wednesday, January 27 | 8:00AM - 11:45AM
From Precision Medicine to Therapies
Room: Eldorado A

Speaker 1 of 7
* Cheryl Wellington, University of British Columbia, Canada

Wednesday, January 27 | 8:00AM - 11:45AM
From Precision Medicine to Therapies
Room: Eldorado A

Speaker 2 of 7
Ramon Diaz-Arrastia, Uniformed Services University of the Health Sciences, USA
Endophenotypes of Traumatic Brain Injury: What We Need to Know for the Next Generation of TBI Clinical Trials

Wednesday, January 27 | 8:00AM - 11:45AM
From Precision Medicine to Therapies
Room: Eldorado A

Speaker 3 of 7
Kaj Blennow, University of Gothenburg, Sweden
Fluid Biomarkers for TBI – Research and Clinical Applications

Wednesday, January 27 | 8:00AM - 11:45AM
From Precision Medicine to Therapies
Room: Eldorado A

Speaker 4 of 7
Michael Chopp, Henry Ford Hospital, USA
Novel Neurorestorative Therapies for Remodeling the CNS and Enhancing Neurological Recovery Post TBI

Wednesday, January 27 | 8:00AM - 11:45AM
From Precision Medicine to Therapies
Room: Eldorado A

Speaker 5 of 7
Dallas C. Hack, USA
TBI Clinical Trials: The Path Forward

Wednesday, January 27 | 8:00AM - 11:45AM
From Precision Medicine to Therapies
Room: Eldorado A

Speaker 6 of 7
Tatyana Gudz, Medical University of South Carolina, USA
Short Talk: Targeting Sphingosine to Protect Mitochondria after Traumatic Brain Injury

Wednesday, January 27 | 8:00AM - 11:45AM
From Precision Medicine to Therapies
Room: Eldorado A

Speaker 7 of 7
Vivian Y.H. Hook, University of California, San Diego, USA
Short Talk: Cathepsin B is a Validated Drug Target for Traumatic Brain Injury

Wednesday, January 27 | 8:00AM - 11:00AM
Axons and Disease
This session is from Axons
Room: Eldorado B

Speaker 1 of 7
* James Shorter, University of Pennsylvania, USA


Wednesday, January 27 | 8:00AM - 11:00AM
Axons and Disease
This session is from Axons
Room: Eldorado B

Speaker 2 of 7
* Patti Murphy, University of Pennsylvania, USA


Wednesday, January 27 | 8:00AM - 11:00AM
Axons and Disease
This session is from Axons
Room: Eldorado B

Speaker 3 of 7
Sung O.K. Yoon, Ohio State University, USA
Role of JNK3 in Development of Alzheimer's


Wednesday, January 27 | 8:00AM - 11:00AM
Axons and Disease
This session is from Axons
Room: Eldorado B

Speaker 4 of 7
Vincenzo De Paola, Imperial College London, UK
Long-Term Imaging of Axon Growth and Calcium Activity in Human iPSC- Derived Neurons from Healthy and Down Syndrome Donors Grafted in the Adult Mouse Brain


Wednesday, January 27 | 8:00AM - 11:00AM
Axons and Disease
This session is from Axons
Room: Eldorado B

Speaker 5 of 7
Ralph A. Nixon, New York University, Langone Medical Center, USA
Autophagy in Neurological Disorders


Wednesday, January 27 | 8:00AM - 11:00AM
Axons and Disease
This session is from Axons
Room: Eldorado B

Speaker 6 of 7
Swetha Gowrishankar, University of Illinois at Chicago, USA
Short Talk: Contributions of Amyloid Plaque-Associated Axonal Lysosome Transport and Maturation Defects to Alzheimer’s Disease Pathology


Wednesday, January 27 | 8:00AM - 11:00AM
Axons and Disease
This session is from Axons
Room: Eldorado B

Speaker 7 of 7
Eran Perlson, Tel Aviv University, Israel


Wednesday, January 27 | 9:40AM - 10:00AM
Coffee Break
Room: Concourse


Wednesday, January 27 | 11:45AM - 5:00PM
On Own for Lunch


Wednesday, January 27 | 2:30PM - 4:30PM
Axon-Glia-Blood Vessel Interactions
This session is from Axons
Room: Eldorado B

Speaker 1 of 6
* Jeffery L. Twiss, University of South Carolina, USA


Wednesday, January 27 | 2:30PM - 4:30PM
Axon-Glia-Blood Vessel Interactions
This session is from Axons
Room: Eldorado B

Speaker 2 of 6
* Eva Klinman, University of Pennsylvania, USA


Wednesday, January 27 | 2:30PM - 4:30PM
Axon-Glia-Blood Vessel Interactions
This session is from Axons
Room: Eldorado B

Speaker 3 of 6
Mary A. Logan, Oregon Health & Science University, USA
Age-Dependent Changes in Glial Responses to Axon Injury and Disease


Wednesday, January 27 | 2:30PM - 4:30PM
Axon-Glia-Blood Vessel Interactions
This session is from Axons
Room: Eldorado B

Speaker 4 of 6
Patrizia Casaccia, Advanced Science Research Center, USA
Epigenetic Mechanisms Modulating Oligodendroglial Development and Function


Wednesday, January 27 | 2:30PM - 4:30PM
Axon-Glia-Blood Vessel Interactions
This session is from Axons
Room: Eldorado B

Speaker 5 of 6
Chenghua Gu, Harvard Medical School, USA
Interactions between Nervous and Vascular Systems in the CNS


Wednesday, January 27 | 2:30PM - 4:30PM
Axon-Glia-Blood Vessel Interactions
This session is from Axons
Room: Eldorado B

Speaker 6 of 6
Subhojit Roy, University of Wisconsin Madison, USA
Short Talk: A Two-Tier Assembly of F-actin in Axons: 'Actin Rings' and 'Actin Trails'


Wednesday, January 27 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Wednesday, January 27 | 5:00PM - 6:45PM
Therapeutic Approaches to TBI
Room: Eldorado A

Speaker 1 of 5
* Ramon Diaz-Arrastia, Uniformed Services University of the Health Sciences, USA

Wednesday, January 27 | 5:00PM - 6:45PM
Therapeutic Approaches to TBI
Room: Eldorado A

Speaker 2 of 5
Peter Walter, HHMI/University of California, San Francisco, USA
Short Talk: Inhibition of the Integrated Stress Response Restores Cognition after Brain Injury

Wednesday, January 27 | 5:00PM - 6:45PM
Therapeutic Approaches to TBI
Room: Eldorado A

Speaker 3 of 5
Ciaran Hill, University of Cambridge, UK
Short Talk: A Novel Organotypic Brain Slice Model of Traumatic Stretch Injury

Wednesday, January 27 | 5:00PM - 6:45PM
Therapeutic Approaches to TBI
Room: Eldorado A

Speaker 4 of 5
Richard M. Ransohoff, Third Rock Ventures, USA
Microglia: A Reintroduction

Wednesday, January 27 | 5:00PM - 6:45PM
Therapeutic Approaches to TBI
Room: Eldorado A

Speaker 5 of 5
David K. Menon, University of Cambridge, UK
What Do We Know About TBI? Where Do We Need To Go?

Wednesday, January 27 | 5:00PM - 7:00PM
Axon, Pathogens and Prion-Like Proteins
This session is from Axons
Room: Eldorado B

Speaker 1 of 5
* Francisca C. Bronfman, Catholic University, Chile


Wednesday, January 27 | 5:00PM - 7:00PM
Axon, Pathogens and Prion-Like Proteins
This session is from Axons
Room: Eldorado B

Speaker 2 of 5
Giampietro Schiavo, University College London, UK
Inhibition of Specific Protein Kinases Rescues Retrograde Axonal Transport Defects in Amyotrophic Lateral Sclerosis


Wednesday, January 27 | 5:00PM - 7:00PM
Axon, Pathogens and Prion-Like Proteins
This session is from Axons
Room: Eldorado B

Speaker 3 of 5
James Shorter, University of Pennsylvania, USA
Potentiated Protein Disaggregates to Counter Neurodegenerative Disease


Wednesday, January 27 | 5:00PM - 7:00PM
Axon, Pathogens and Prion-Like Proteins
This session is from Axons
Room: Eldorado B

Speaker 4 of 5
Andres Couve, Universidad de Chile, Chile
Short Talk: The Endoplasmic Reticulum and Protein Trafficking in Axons


Wednesday, January 27 | 5:00PM - 7:00PM
Axon, Pathogens and Prion-Like Proteins
This session is from Axons
Room: Eldorado B

Speaker 5 of 5
Lauren Walker, University of Pennsylvania, USA
Short Talk: Axon Self-Destruction: Integrating Sarm1 Activation, NAD+ Depletion, and MAPK Signaling


Wednesday, January 27 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Eldorado A


Wednesday, January 27 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions
This session is from Axons
Room: Eldorado B

Speaker 1 of 3
* Giampietro Schiavo, University College London, UK


Wednesday, January 27 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions
This session is from Axons
Room: Eldorado B

Speaker 2 of 3
* Bruce D. Carter, Vanderbilt University School of Medicine, USA


Wednesday, January 27 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions
This session is from Axons
Room: Eldorado B

Speaker 3 of 3
* Rejji Kuruvilla, Johns Hopkins University, USA


Wednesday, January 27 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Anasazi Ballroom
No registration fees are used to fund alcohol served at this function.

Wednesday, January 27 | 8:00PM - 11:00PM
Entertainment
Room: Anasazi Ballroom
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Wednesday, January 27 | 8:15PM - 11:00PM
Cash Bar
Room: Anasazi Ballroom


Thursday, January 28 | 10:25AM - 10:25AM
Departure


*Session Chair.