Web Desc
New Approaches to Vaccines for Human and Veterinary Tropical Diseases
Organizer(s): Vish Nene, Vishva M. Dixit, Rafi Ahmed and Yasmine Belkaid
Date: May 22 - 26, 2016
Location: Southern Sun Cape Sun, Cape Town, Western Cape, South Africa
Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation. Supported by: Robert Bosch Stiftung GmbH
Summary of Meeting:
Human and livestock vaccines can contribute to improved human welfare and income generation by maintaining human health and meeting the demand for meat, milk and fish in developing countries. All of these factors contribute to the growing importance of improving food safety, availability and nutritional security. An important component of this Keystone Symposia meeting will be to stimulate crosstalk between the human and veterinary vaccine communities by highlighting cross-cutting technical advances and new science and knowledge from laboratory and field research. The meeting will also provide a rare opportunity for scientists from the Northern and Southern hemispheres to interact and pool resources and knowledge in the common fight against tropical diseases.
Global Health Travel Award Deadline: December 22 2015
Scholarship Deadline: January 21 2016
Discounted Abstract Deadline: January 21 2016
Abstract Deadline: February 23 2016
Discounted Registration Deadline: March 22 2016
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Bill & Melinda Gates FoundationRobert Bosch Stiftung GmbH
We gratefully acknowledge additional support for this conference from:
Sanofi Pasteur
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.

GlaxoSmithKline Vaccines

Sanaria Inc.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, May 22 | 4:00PM - 8:00PM
Arrival and Registration
Room: 3rd Floor Lobby


Sunday, May 22 | 6:00PM - 8:00PM
Welcome Mixer
Room: 3rd Floor Lobby
No registration fees are used to fund alcohol served at this function.

Monday, May 23 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Monday, May 23 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: VOC North

Speaker 1 of 2
* Vish Nene, International Livestock Research Institute, Kenya

Monday, May 23 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: VOC North

Speaker 2 of 2
Guy Palmer, Washington State University, USA
Vaccination as a Driver to Achieve the Sustainability Development Goals

Monday, May 23 | 9:30AM - 11:45AM
The Challenge of Helminth Vaccines
Room: VOC North

Speaker 1 of 5
* Vish Nene, International Livestock Research Institute, Kenya

Monday, May 23 | 9:30AM - 11:45AM
The Challenge of Helminth Vaccines
Room: VOC North

Speaker 2 of 5
Ben Makepeace, University of Liverpool, UK
The Onchocerciasis Vaccine for Africa Initiative: A Critical Role for Cattle

Monday, May 23 | 9:30AM - 11:45AM
The Challenge of Helminth Vaccines
Room: VOC North

Speaker 3 of 5
Donald A. Harn, University of Georgia College of Veterinary Medicine, USA
Developing Schistosome Vaccines for People and Livestock

Monday, May 23 | 9:30AM - 11:45AM
The Challenge of Helminth Vaccines
Room: VOC North

Speaker 4 of 5
Marshall Lightowlers, University of Melbourne, Australia
Effective Recombinant Vaccines against Cysticercosis and Cystic Echinococcosis

Monday, May 23 | 9:30AM - 11:45AM
The Challenge of Helminth Vaccines
Room: VOC North

Speaker 5 of 5
Rebecca Katie Shears, University of Manchester, UK
Short Talk: Vaccine Design for Whipworm: Type 2 Cytokine Inducing Antigens from Trichuris

Monday, May 23 | 10:10AM - 10:30AM
Coffee Break
Room: 3rd Floor Foyer


Monday, May 23 | 11:45AM - 2:30PM
On Own for Lunch


Monday, May 23 | 11:45AM - 1:00PM
Poster Setup
Room: VOC South


Monday, May 23 | 1:00PM - 10:00PM
Poster Viewing
Room: VOC South


Monday, May 23 | 2:30PM - 4:30PM
Workshop 1
Room: VOC North

Speaker 1 of 6
* Thomas J. Scriba, University of Cape Town, South Africa

Monday, May 23 | 2:30PM - 4:30PM
Workshop 1
Room: VOC North

Speaker 2 of 6
Mpala Mwanza, Tropgan University Teaching Hospital, Zambia
Retinoic Acid Elicits a Coordinated Expression of Gut Homing Markers on T Lymphocytes with Oral Typhoid, But Not Viral, Vaccines in Zambian Men

Monday, May 23 | 2:30PM - 4:30PM
Workshop 1
Room: VOC North

Speaker 3 of 6
Eren Zink, Uppsala University, Sweden
African Experiences of International Collaboration in Research on Tropical Diseases: A Qualitative Study of Scientists in Uganda, Ghana and Zimbabwe

Monday, May 23 | 2:30PM - 4:30PM
Workshop 1
Room: VOC North

Speaker 4 of 6
Dawit Gebreegziabiher Hagos, Mekelle University, Ethiopia
The Effect of Maternal Helminth Infection on Maternal and Neonatal Immune Function and Immunity to Tuberculosis

Monday, May 23 | 2:30PM - 4:30PM
Workshop 1
Room: VOC North

Speaker 5 of 6
Katja Becker, University of Zurich, Switzerland
Molecular Characterization of Posttranslational Modifications in Mycobacterial Lipoproteins

Monday, May 23 | 2:30PM - 4:30PM
Workshop 1
Room: VOC North

Speaker 6 of 6
Murad R. Mamedov, University of California, San Francisco, USA
Highly Focused Post-Acute gammadelta T Cell Response to Mouse and Human Malaria

Monday, May 23 | 4:30PM - 5:00PM
Coffee Available
Room: 3rd Floor Foyer


Monday, May 23 | 5:00PM - 7:30PM
Human and Bovine Tuberculosis
Room: VOC North

Speaker 1 of 6
* Yasmine Belkaid, NIAID, National Institutes of Health, USA

Monday, May 23 | 5:00PM - 7:30PM
Human and Bovine Tuberculosis
Room: VOC North

Speaker 2 of 6
Helen McShane, Jenner Institute, UK
Clinical Trials with New TB Vaccines

Monday, May 23 | 5:00PM - 7:30PM
Human and Bovine Tuberculosis
Room: VOC North

Speaker 3 of 6
Carlos Martin, University of Zaragoza, Spain
MTBVAC: An Attenuated Vaccine based on the Human Pathogen Mycobacterium tuberculosis in Clinical Trials

Monday, May 23 | 5:00PM - 7:30PM
Human and Bovine Tuberculosis
Room: VOC North

Speaker 4 of 6
Glyn Hewinson, Animal & Plant Health Agency, UK
A One Health Approach to Developing Vaccines against Bovine Tuberculosis

Monday, May 23 | 5:00PM - 7:30PM
Human and Bovine Tuberculosis
Room: VOC North

Speaker 5 of 6
Thomas J. Scriba, University of Cape Town, South Africa
T Cell Differentiation: Implications for Tuberculosis Vaccine Development

Monday, May 23 | 5:00PM - 7:30PM
Human and Bovine Tuberculosis
Room: VOC North

Speaker 6 of 6
Virginie Rozot, University of Cape Town, South Africa
Short Talk: Deep Immuno-Phenotyping and Functional Assessment of Leukocyte Responses to M. Tuberculosis using Cytometry by Time-of-Flight

Monday, May 23 | 7:30PM - 8:30PM
Social Hour with Lite Bites
Room: VOC South
No registration fees are used to fund alcohol served at this function.

Monday, May 23 | 7:30PM - 10:00PM
Poster Session 1
Room: VOC South


Tuesday, May 24 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Tuesday, May 24 | 8:00AM - 8:30AM
Poster Setup
Room: VOC South


Tuesday, May 24 | 8:30AM - 5:00PM
Poster Viewing
Room: VOC South


Tuesday, May 24 | 8:30AM - 11:30AM
Vaccination Strategies for Malaria
Room: VOC North

Speaker 1 of 6
* Helen McShane, Jenner Institute, UK

Tuesday, May 24 | 8:30AM - 11:30AM
Vaccination Strategies for Malaria
Room: VOC North

Speaker 2 of 6
William Ballou, GlaxoSmithKline, USA
RTS/S - Current Status

Tuesday, May 24 | 8:30AM - 11:30AM
Vaccination Strategies for Malaria
Room: VOC North

Speaker 3 of 6
Thomas L. Richie, Sanaria Inc., USA
The March toward Licensure and Deployment of a Highly Protective PfSPZ Malaria Vaccine

Tuesday, May 24 | 8:30AM - 11:30AM
Vaccination Strategies for Malaria
Room: VOC North

Speaker 4 of 6
Shahid Khan, Leiden University Medical Center, Netherlands
Development of Genetically Attenuated Parasite (GAP) Vaccine against Malaria

Tuesday, May 24 | 8:30AM - 11:30AM
Vaccination Strategies for Malaria
Room: VOC North

Speaker 5 of 6
Adrian V. S. Hill, Jenner Institute, University of Oxford, UK
Improving Pre-Erythrocytic Malaria Subunit Vaccines

Tuesday, May 24 | 8:30AM - 11:30AM
Vaccination Strategies for Malaria
Room: VOC North

Speaker 6 of 6
Julius C. R. Hafalla, London School of Hygiene and Tropical Medicine, UK
Short Talk: Broad Repertoire of the CD8+ T Cell Response to Malaria Pre-Erythrocytic Stage Infection

Tuesday, May 24 | 9:50AM - 10:10AM
Coffee Break
Room: 3rd Floor Foyer


Tuesday, May 24 | 11:30AM - 12:30PM
Lunch
Room: VOC South


Tuesday, May 24 | 12:00PM - 2:30PM
Poster Session 2
Room: VOC South


Tuesday, May 24 | 2:30PM - 4:30PM
Workshop 2
Room: VOC North

Speaker 1 of 8
* George Warimwe, University of Oxford, UK

Tuesday, May 24 | 2:30PM - 4:30PM
Workshop 2
Room: VOC North

Speaker 2 of 8
* Søren Buus, University of Copenhagen, Denmark

Tuesday, May 24 | 2:30PM - 4:30PM
Workshop 2
Room: VOC North

Speaker 3 of 8
Sara Suliman, Brigham and Women's Hospital, USA
BCG Revaccination of Latently Mycobacterium tuberculosis (M.tb) Infected Adults Induces Durable Unconventional Immune Responses

Tuesday, May 24 | 2:30PM - 4:30PM
Workshop 2
Room: VOC North

Speaker 4 of 8
Brandon Sack, Center for Infectious Disease Research, USA
A Phase 1 Trial to Assess the Safety, Attenuation and Immunogenicity of Genetically-attenuated p52-/ p36-/sap1- Gene Knockout Plasmodium falciparum Parasites

Tuesday, May 24 | 2:30PM - 4:30PM
Workshop 2
Room: VOC North

Speaker 5 of 8
Anne Rechtien, University Medical Center Hamburg-Eppendorf, Germany
A Signature of Early Innate Immune Markers Predicts GP-Specific Antibody Responses following Vaccination with the Ebola Vaccine rVSV-ZEBOV

Tuesday, May 24 | 2:30PM - 4:30PM
Workshop 2
Room: VOC North

Speaker 6 of 8
Ismaila Shittu, National Veterinary Research Institute, Nigeria
Highly Pathogenic Avian Influenza (H5N1) Diagnosis in Nigeria, 2015: Widespread Involvement of Co-Infection with Infectious Bronchitis and Newcastle Disease Viruses

Tuesday, May 24 | 2:30PM - 4:30PM
Workshop 2
Room: VOC North

Speaker 7 of 8
Clement Adebajo Meseko, National Veterinary Resesrch Institute, Vom, Nigeria
Isolation and Molecular Characterization of P4b Core Protein of Recent Field Cases of Fowl Poxvirus in Nigeria Compared to Vaccine Strain

Tuesday, May 24 | 2:30PM - 4:30PM
Workshop 2
Room: VOC North

Speaker 8 of 8
Karl Dietrich Brune, University of Oxford, UK
Plug-and-Display: Genetically Encoded Superglue for Decoration of Virus-Like and Nano-Particles

Tuesday, May 24 | 4:30PM - 5:00PM
Coffee Available
Room: 3rd Floor Foyer


Tuesday, May 24 | 5:00PM - 7:00PM
Vaccination Strategies for East Coast Fever in Cattle
Room: VOC North

Speaker 1 of 5
* Shahid Khan, Leiden University Medical Center, Netherlands

Tuesday, May 24 | 5:00PM - 7:00PM
Vaccination Strategies for East Coast Fever in Cattle
Room: VOC North

Speaker 2 of 5
Vish Nene, International Livestock Research Institute, Kenya
B-Cell Vaccines against East Coast Fever

Tuesday, May 24 | 5:00PM - 7:00PM
Vaccination Strategies for East Coast Fever in Cattle
Room: VOC North

Speaker 3 of 5
Ivan Morrison, University of Edinburgh, UK
Vaccination against Theileria Parasites by Induction of T Cell Responses

Tuesday, May 24 | 5:00PM - 7:00PM
Vaccination Strategies for East Coast Fever in Cattle
Room: VOC North

Speaker 4 of 5
Joana Carneiro da Silva, University of Maryland School of Medicine, USA
Genomics of Vaccine Efficacy: Lessons from the Buffalo Wildlife Reservoir of East Coast Fever

Tuesday, May 24 | 5:00PM - 7:00PM
Vaccination Strategies for East Coast Fever in Cattle
Room: VOC North

Speaker 5 of 5
Jerome Nyhalah Dinga, University of Buea, Cameroon
Short Talk: Immune Responses to TpUB05: A Homologue of Plasmodium falciparum UB05 Antigen, is Indicative of Protective Immunity against East Coast Fever

Tuesday, May 24 | 7:00PM - 7:00PM
On Own for Dinner


Wednesday, May 25 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Wednesday, May 25 | 8:30AM - 11:30AM
New Approaches to Viral Vaccines
Room: VOC North

Speaker 1 of 6
* William T. Golde, Moredun Research Institute, UK

Wednesday, May 25 | 8:30AM - 11:30AM
New Approaches to Viral Vaccines
Room: VOC North

Speaker 2 of 6
Louis F. Fries III, Novavax, Inc., USA
Recombinant Nanoparticle Vaccines: Respiratory and Emerging Viruses

Wednesday, May 25 | 8:30AM - 11:30AM
New Approaches to Viral Vaccines
Room: VOC North

Speaker 3 of 6
Rafi Ahmed, Emory University School of Medicine, USA
Sustained Immune Activation in Ebola Virus Infected Patients

Wednesday, May 25 | 8:30AM - 11:30AM
New Approaches to Viral Vaccines
Room: VOC North

Speaker 4 of 6
George Warimwe, University of Oxford, UK
One Health Vaccinology for Emerging Infectious Diseases

Wednesday, May 25 | 8:30AM - 11:30AM
New Approaches to Viral Vaccines
Room: VOC North

Speaker 5 of 6
Bryan Charleston, Pirbright Institute, UK
Structural Enhancements to Foot-and-Mouth Disease Vaccines

Wednesday, May 25 | 8:30AM - 11:30AM
New Approaches to Viral Vaccines
Room: VOC North

Speaker 6 of 6
Ashley St. John, Duke-NUS Medical School, Singapore
Short Talk: Serocomplex Cross-Reactive Immunity Primes for Protection during Flavivirus Infections

Wednesday, May 25 | 9:50AM - 10:10AM
Coffee Break
Room: 3rd Floor Foyer


Wednesday, May 25 | 11:30AM - 2:30PM
On Own for Lunch


Wednesday, May 25 | 11:30AM - 1:00PM
Poster Setup
Room: VOC South


Wednesday, May 25 | 1:00PM - 10:00PM
Poster Viewing
Room: VOC South


Wednesday, May 25 | 4:30PM - 5:00PM
Coffee Available
Room: 3rd Floor Foyer


Wednesday, May 25 | 5:00PM - 7:00PM
Understanding Immune Responses to Inform Vaccine Design
Room: VOC North

Speaker 1 of 5
* Rafi Ahmed, Emory University School of Medicine, USA

Wednesday, May 25 | 5:00PM - 7:00PM
Understanding Immune Responses to Inform Vaccine Design
Room: VOC North

Speaker 2 of 5
Bali Pulendran, Stanford University School of Medicine, USA
Systems Vaccinology

Wednesday, May 25 | 5:00PM - 7:00PM
Understanding Immune Responses to Inform Vaccine Design
Room: VOC North

Speaker 3 of 5
Yasmine Belkaid, NIAID, National Institutes of Health, USA
Vaccine Responses and Commensal Control of Tissue Immunity

Wednesday, May 25 | 5:00PM - 7:00PM
Understanding Immune Responses to Inform Vaccine Design
Room: VOC North

Speaker 4 of 5
William T. Golde, Moredun Research Institute, UK
Analysis of T and B Lymphocyte Responses to Recombinant Vaccines for Foot-and-Mouth Disease (FMD)

Wednesday, May 25 | 5:00PM - 7:00PM
Understanding Immune Responses to Inform Vaccine Design
Room: VOC North

Speaker 5 of 5
Denise L. Doolan, James Cook University, Australia
Short Talk: Systems-Based Characterization of Immunity to Plasmodium Infection in Humans

Wednesday, May 25 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: VOC South
No registration fees are used to fund alcohol served at this function.

Wednesday, May 25 | 7:30PM - 10:00PM
Poster Session 3
Room: VOC South


Thursday, May 26 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Thursday, May 26 | 8:30AM - 11:00AM
Profiling Immune Responses to Infection and Vaccines
Room: VOC North

Speaker 1 of 5
* Vishva M. Dixit, Genentech, Inc., USA

Thursday, May 26 | 8:30AM - 11:00AM
Profiling Immune Responses to Infection and Vaccines
Room: VOC North

Speaker 2 of 5
Søren Buus, University of Copenhagen, Denmark
Large-Scale Mapping of T Cell Epitopes

Thursday, May 26 | 8:30AM - 11:00AM
Profiling Immune Responses to Infection and Vaccines
Room: VOC North

Speaker 3 of 5
William H. Robinson, Stanford University School of Medicine, USA
Antibody Discovery via Single B Cell Analyses

Thursday, May 26 | 8:30AM - 11:00AM
Profiling Immune Responses to Infection and Vaccines
Room: VOC North

Speaker 4 of 5
Sachdev S. Sidhu, University of Toronto, Canada
Synthetic Proteins as Therapeutics for Infectious Disease

Thursday, May 26 | 8:30AM - 11:00AM
Profiling Immune Responses to Infection and Vaccines
Room: VOC North

Speaker 5 of 5
Christine Dahlke, University Medical Center Hamburg-Eppendorf, Germany
Short Talk: Safety and Reactogenicity of rVSV-ZEBOV: Phase I Trial in Germany

Thursday, May 26 | 9:50AM - 10:10AM
Coffee Break
Room: 3rd Floor Foyer


Thursday, May 26 | 11:00AM - 11:30AM
MConf Demonstration: Virtual Tour
Room: VOC North
Creating collaboration between labs.
Speaker 1 of 1
Kasandra Pillay, Meraka Institute, South Africa
MConf is a web conferencing and collaboration tool for Research and Education

Thursday, May 26 | 11:30AM - 2:30PM
On Own for Lunch


Thursday, May 26 | 2:30PM - 4:30PM
Workshop 3: Bioinformatics in Vaccine Design
Room: VOC North

Speaker 1 of 5
* Joana Carneiro da Silva, University of Maryland School of Medicine, USA

Thursday, May 26 | 2:30PM - 4:30PM
Workshop 3: Bioinformatics in Vaccine Design
Room: VOC North

Speaker 2 of 5
Penny L. Moore, University of the Witwatersrand and National Institute for Communicable Diseases, South Africa
HIV and Antibody Dynamics: Implications for Vaccine Design

Thursday, May 26 | 2:30PM - 4:30PM
Workshop 3: Bioinformatics in Vaccine Design
Room: VOC North

Speaker 3 of 5
Edward P. Rybicki, University of Cape Town, South Africa
Designing Vaccines to be Made in Plants

Thursday, May 26 | 2:30PM - 4:30PM
Workshop 3: Bioinformatics in Vaccine Design
Room: VOC North

Speaker 4 of 5
Dean Everett, Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Malawi
Developing Appropriate Vaccines through Bioinformatics in Africa

Thursday, May 26 | 2:30PM - 4:30PM
Workshop 3: Bioinformatics in Vaccine Design
Room: VOC North

Speaker 5 of 5
W. Florian Fricke, University of Hohenheim, Germany
Automated and Interactive Comparative Genomics Tools for the Identification of Vaccine Candidates

Thursday, May 26 | 4:30PM - 5:00PM
Coffee Available
Room: 3rd Floor Foyer


Thursday, May 26 | 5:00PM - 6:15PM
Synthetic Genomics-Based Vaccines
Room: VOC North

Speaker 1 of 3
* Vish Nene, International Livestock Research Institute, Kenya

Thursday, May 26 | 5:00PM - 6:15PM
Synthetic Genomics-Based Vaccines
Room: VOC North

Speaker 2 of 3
Rino Rappuoli, GlaxoSmithKline Vaccines, Italy
Opportunities and Challenges for Vaccines

Thursday, May 26 | 5:00PM - 6:15PM
Synthetic Genomics-Based Vaccines
Room: VOC North

Speaker 3 of 3
Sanjay Vashee, J. Craig Venter Institute, USA
Synthetic Bacterial and Viral Backbones as Antigen Delivery Vehicles

Thursday, May 26 | 6:15PM - 7:00PM
Closing Keynote Address
Room: VOC North

Speaker 1 of 2
* Vishva M. Dixit, Genentech, Inc., USA

Thursday, May 26 | 6:15PM - 7:00PM
Closing Keynote Address
Room: VOC North

Speaker 2 of 2
Chris Wilson, Bill & Melinda Gates Foundation, USA
Cross-Disciplinary Science to Accelerate the Discovery of Vaccines for Global, Zoonotic and Emerging Infectious Diseases

Thursday, May 26 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: VOC South
No registration fees are used to fund alcohol served at this function.

Thursday, May 26 | 8:00PM - 11:00PM
Entertainment
Room: VOC South
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, May 26 | 8:00PM - 11:00PM
Cash Bar
Room: VOC South


Friday, May 27 | 10:25AM - 10:25AM
Departure


*Session Chair.