Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
	Positive-Strand RNA Viruses (2019E2)

Web Desc
Positive-Strand RNA Viruses Organizer(s): Raul Andino and Peter D. Nagy Date: May 01 - 05, 2016 Location: Hyatt Regency Austin, Austin, TX, USA Sponsored by Merck & Co., Inc. Summary of Meeting: Positive-stranded RNA viruses are significant and emerging human pathogens worldwide. Virus-host interactions and innate responses by the host are intensively studied areas, which promise novel, broad-range and durable antiviral approaches. Topics covered by the meeting include basic advances in research on viral replication structures, virus entry and virus evolution; virus-host interactions, discussed from the virus view on changing the host (including systems biology) and host responses and defense mechanisms; and emerging therapeutics. It is anticipated that rapidly emerging new concepts on virus-host interactions will help the participants to test various host factors for a large number of positive-strand RNA viruses to expand the arsenal of antiviral approaches. This meeting will bring together experts on positive-stranded RNA viruses that will facilitate the rapid progress and dissemination of new concepts in the complex field of virus-host interactions. Also, speakers who are expert with other groups of viruses will be invited to facilitate cross-talk with other areas in virology. Among the speakers will be interdisciplinary scientists who would not normally meet with this group of researchers. Virology, cell biology, genetics, evolution, macromolecular structures/assembly, systems biology and imaging will all be brought together. Scholarship Deadline: January 6 2016 Discounted Abstract Deadline: January 6 2016 Abstract Deadline: February 3 2016 Discounted Registration Deadline: March 2 2016 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: International Symposium on Positive Strand RNA Viruses We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI124477-01 Funding for this conference was made possible (in part) by 1 R13 AI 124477 - 01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Positive-Strand RNA Viruses

Organizer(s): Raul Andino and Peter D. Nagy

Date: May 01 - 05, 2016
Location: Hyatt Regency Austin, Austin, TX, USA

Program


Sunday, May 01 \| 4:00PM - 8:00PM Arrival and Registration Room: Zilker North Lobby
Sunday, May 01 \| 6:00PM - 8:00PM Welcome Mixer Room: Zilker North Lobby No registration fees are used to fund alcohol served at this function.
Monday, May 02 \| 7:30AM - 8:30AM Breakfast Room: Zilker 1-2
Monday, May 02 \| 8:30AM - 9:30AM Welcome and Keynote Address Room: Zilker 3-4 Speaker 1 of 2 * Raul Andino, University of California, San Francisco, USA
Monday, May 02 \| 8:30AM - 9:30AM Welcome and Keynote Address Room: Zilker 3-4 Speaker 2 of 2 Anna Marie Pyle, Yale University, USA Viral RNA Structure and its Recognition by Host and Viral Proteins
Monday, May 02 \| 9:30AM - 11:45AM Systems Biology: From 'Omics' to Function Room: Zilker 3-4 Host-virus interaction uncovered by integration of large data sets (genomics, proteomics, functional genomics, etc.). Speaker 1 of 6 * Peter D. Nagy, University of Kentucky, USA
Monday, May 02 \| 9:30AM - 11:45AM Systems Biology: From 'Omics' to Function Room: Zilker 3-4 Host-virus interaction uncovered by integration of large data sets (genomics, proteomics, functional genomics, etc.). Speaker 2 of 6 Priya S. Shah, University of California, Davis, USA Proteomics, Functional Genomics, eMAPs on Dengue Virus Replicating in Humans and Mosquitoes
Monday, May 02 \| 9:30AM - 11:45AM Systems Biology: From 'Omics' to Function Room: Zilker 3-4 Host-virus interaction uncovered by integration of large data sets (genomics, proteomics, functional genomics, etc.). Speaker 3 of 6 Shin-Ru Shih, Chang Gung University, Taiwan Host-Factors Involved in Enterovirus Replication
Monday, May 02 \| 9:30AM - 11:45AM Systems Biology: From 'Omics' to Function Room: Zilker 3-4 Host-virus interaction uncovered by integration of large data sets (genomics, proteomics, functional genomics, etc.). Speaker 4 of 6 Benjamin R. TenOever, Icahn School of Medicine at Mount Sinai, USA Functional Antiviral Genomics through in vivo RNAi Screens
Monday, May 02 \| 9:30AM - 11:45AM Systems Biology: From 'Omics' to Function Room: Zilker 3-4 Host-virus interaction uncovered by integration of large data sets (genomics, proteomics, functional genomics, etc.). Speaker 5 of 6 Jan E. Carette, Stanford University, USA Short Talk: Genetic Knockout Screens Identify Host Genes Required For Dengue Virus Replication
Monday, May 02 \| 9:30AM - 11:45AM Systems Biology: From 'Omics' to Function Room: Zilker 3-4 Host-virus interaction uncovered by integration of large data sets (genomics, proteomics, functional genomics, etc.). Speaker 6 of 6 Sunnie R. Thompson, University of Alabama, Birmingham, USA Short Talk: Identification of Host Factors that Interact with Dengue Virus RNA in Cell Culture
Monday, May 02 \| 10:00AM - 10:20AM Coffee Break Room: Zilker North Lobby
Monday, May 02 \| 11:45AM - 5:00PM On Own for Lunch
Monday, May 02 \| 11:45AM - 1:00PM Poster Setup Room: Zilker 1-2
Monday, May 02 \| 1:00PM - 10:00PM Poster Viewing Room: Zilker 1-2
Monday, May 02 \| 2:30PM - 4:30PM Workshop 1: Recombination and Replication Fidelity, RdRp Str ucture Room: Zilker 3-4 Speaker 1 of 9 * Karla A. Kirkegaard, Stanford University School of Medicine, USA
Monday, May 02 \| 2:30PM - 4:30PM Workshop 1: Recombination and Replication Fidelity, RdRp Str ucture Room: Zilker 3-4 Speaker 2 of 9 David J. Barton, University of Colorado Denver, USA Polymerase Structure-Function and Picornavirus RNA Recombination
Monday, May 02 \| 2:30PM - 4:30PM Workshop 1: Recombination and Replication Fidelity, RdRp Str ucture Room: Zilker 3-4 Speaker 3 of 9 Patrick T. Dolan, Stanford University, USA Population Sequencing Reveals the Host-Specific Adaptive Landscapes of Dengue Virus
Monday, May 02 \| 2:30PM - 4:30PM Workshop 1: Recombination and Replication Fidelity, RdRp Str ucture Room: Zilker 3-4 Speaker 4 of 9 Gonzalo Moratorio, Institut Pasteur, France Cornering RNA Viruses by Constraining their Sequence Space
Monday, May 02 \| 2:30PM - 4:30PM Workshop 1: Recombination and Replication Fidelity, RdRp Str ucture Room: Zilker 3-4 Speaker 5 of 9 Craig E. Cameron, UNC School of Medicine, USA New, Functional Forms of HCV NS5A Protein in vivo?
Monday, May 02 \| 2:30PM - 4:30PM Workshop 1: Recombination and Replication Fidelity, RdRp Str ucture Room: Zilker 3-4 Speaker 6 of 9 Alexander E. Gorbalenya, Leiden University Medical Center, Netherlands NiRAN, Nidovirus RdRp-Associated Nucleotidyltransferase: First Enzyme Exclusively Associated with an Order of +RNA Viruses
Monday, May 02 \| 2:30PM - 4:30PM Workshop 1: Recombination and Replication Fidelity, RdRp Str ucture Room: Zilker 3-4 Speaker 7 of 9 James Bert Flanegan, University of Florida, USA Poliovirus Multifunctional Precursor Proteins Required for Replication Complex Assembly, VPgpUpU Synthesis and RNA Replication
Monday, May 02 \| 2:30PM - 4:30PM Workshop 1: Recombination and Replication Fidelity, RdRp Str ucture Room: Zilker 3-4 Speaker 8 of 9 Kay Choi, University of Texas Medical Branch, USA Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface
Monday, May 02 \| 2:30PM - 4:30PM Workshop 1: Recombination and Replication Fidelity, RdRp Str ucture Room: Zilker 3-4 Speaker 9 of 9 Chloé Jaubert, Universite de Bordeaux, France RNA Genomic Dimerization and Hepatitis C Virus Replication
Monday, May 02 \| 4:30PM - 5:00PM Coffee Available Room: Zilker North Lobby
Monday, May 02 \| 5:00PM - 7:00PM Entry, Trafficking and Exiting Room: Zilker 3-4 Virus receptor interactions, intracellular trafficking, and mechanisms of egress. Speaker 1 of 5 * Andres Merits, University of Tartu, Estonia
Monday, May 02 \| 5:00PM - 7:00PM Entry, Trafficking and Exiting Room: Zilker 3-4 Virus receptor interactions, intracellular trafficking, and mechanisms of egress. Speaker 2 of 5 Félix Rey, Institut Pasteur, France Eliciting Cross-Reactive Antibodies Neutralizing Dengue Virus: A Structural View
Monday, May 02 \| 5:00PM - 7:00PM Entry, Trafficking and Exiting Room: Zilker 3-4 Virus receptor interactions, intracellular trafficking, and mechanisms of egress. Speaker 3 of 5 Carolyn B. Coyne, University of Pittsburgh, USA Roadblocks: Polarized Cells as Barriers to RNA Virus Entry and Infection
Monday, May 02 \| 5:00PM - 7:00PM Entry, Trafficking and Exiting Room: Zilker 3-4 Virus receptor interactions, intracellular trafficking, and mechanisms of egress. Speaker 4 of 5 Julie K. Pfeiffer, University of Texas Southwestern Medical Center, USA Enteroviruses and the Microbiota
Monday, May 02 \| 5:00PM - 7:00PM Entry, Trafficking and Exiting Room: Zilker 3-4 Virus receptor interactions, intracellular trafficking, and mechanisms of egress. Speaker 5 of 5 Maria Guadalupe Martinez, INSERM 1052 Centre de Recherche en Cancerologie, CNRS 5286, France Short Talk: Alphavirus Budding: How Viruses Remodel the Cell During Exit
Monday, May 02 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Zilker 1-2 No registration fees are used to fund alcohol served at this function.
Monday, May 02 \| 7:30PM - 10:00PM Poster Session 1 Room: Zilker 1-2
Tuesday, May 03 \| 7:30AM - 8:30AM Breakfast Room: Zilker 1-2
Tuesday, May 03 \| 8:00AM - 8:30AM Poster Setup Room: Zilker 1-2
Tuesday, May 03 \| 8:30AM - 5:00PM Poster Viewing Room: Zilker 1-2
Tuesday, May 03 \| 8:30AM - 11:30AM Replication Organelles, Membranes, Proteins, Lipids and Stuf f... Room: Zilker 3-4 How do virus construct alter the cell architecture to create a RNA replication favorable environment. Speaker 1 of 7 * Raul Andino, University of California, San Francisco, USA
Tuesday, May 03 \| 8:30AM - 11:30AM Replication Organelles, Membranes, Proteins, Lipids and Stuf f... Room: Zilker 3-4 How do virus construct alter the cell architecture to create a RNA replication favorable environment. Speaker 2 of 7 Ralf Bartenschlager, Heidelberg University, Germany Cell Biology of Viral Replication Cycles: A Comparison of Hepatitis C Virus and Dengue Virus
Tuesday, May 03 \| 8:30AM - 11:30AM Replication Organelles, Membranes, Proteins, Lipids and Stuf f... Room: Zilker 3-4 How do virus construct alter the cell architecture to create a RNA replication favorable environment. Speaker 3 of 7 Richard J. Kuhn, Purdue University, USA Structure-Function Studies of Flavivirus Replication Proteins
Tuesday, May 03 \| 8:30AM - 11:30AM Replication Organelles, Membranes, Proteins, Lipids and Stuf f... Room: Zilker 3-4 How do virus construct alter the cell architecture to create a RNA replication favorable environment. Speaker 4 of 7 Frank van Kuppeveld, Utrecht University, Netherlands Short Talk: An Enterovirus Mutant that can Replicate in the Absence of Replication Organelles
Tuesday, May 03 \| 8:30AM - 11:30AM Replication Organelles, Membranes, Proteins, Lipids and Stuf f... Room: Zilker 3-4 How do virus construct alter the cell architecture to create a RNA replication favorable environment. Speaker 5 of 7 Paul Ahlquist, University of Wisconsin-Madison, USA Protein, RNA and Membrane Interactions in Positive-Strand RNA virus Genome Replication
Tuesday, May 03 \| 8:30AM - 11:30AM Replication Organelles, Membranes, Proteins, Lipids and Stuf f... Room: Zilker 3-4 How do virus construct alter the cell architecture to create a RNA replication favorable environment. Speaker 6 of 7 Michael S. Diamond, Washington University School of Medicine, USA A Genome-Wide CRISPR/Cas9 Screen Identifies Novel Host Factors Required for Flavivirus Infection
Tuesday, May 03 \| 8:30AM - 11:30AM Replication Organelles, Membranes, Proteins, Lipids and Stuf f... Room: Zilker 3-4 How do virus construct alter the cell architecture to create a RNA replication favorable environment. Speaker 7 of 7 Hongliang Wang, University of Michigan, USA Short Talk: Pulse-Chase Imaging Reveals Continuous and Rapid Turnover of Hepatitis C Virus Replication Organelles
Tuesday, May 03 \| 9:50AM - 10:10AM Coffee Break Room: Zilker North Lobby
Tuesday, May 03 \| 11:30AM - 12:30PM Lunch Room: Zilker 1-2
Tuesday, May 03 \| 12:00PM - 2:30PM Poster Session 2 Room: Zilker 1-2
Tuesday, May 03 \| 4:30PM - 5:00PM Coffee Available Room: Zilker North Lobby
Tuesday, May 03 \| 5:00PM - 7:00PM Replication Enzymes and Other Factors Room: Zilker 3-4 Both viral and cellular proteins and RNAs catalyzing the formation of RNA progeny. Speaker 1 of 6 * Richard William Hardy, Indiana University, USA
Tuesday, May 03 \| 5:00PM - 7:00PM Replication Enzymes and Other Factors Room: Zilker 3-4 Both viral and cellular proteins and RNAs catalyzing the formation of RNA progeny. Speaker 2 of 6 K. Andrew White, York University, Canada Regulation of Tombusvirus Processes by Long-range RNA-RNA Interactions
Tuesday, May 03 \| 5:00PM - 7:00PM Replication Enzymes and Other Factors Room: Zilker 3-4 Both viral and cellular proteins and RNAs catalyzing the formation of RNA progeny. Speaker 3 of 6 Eric J. Snijder, Leiden University Medical Center, Netherlands An Unprecedented Protein-Stimulated -2/-1 Ribosomal Frameshift Mechanism in Arteriviruses
Tuesday, May 03 \| 5:00PM - 7:00PM Replication Enzymes and Other Factors Room: Zilker 3-4 Both viral and cellular proteins and RNAs catalyzing the formation of RNA progeny. Speaker 4 of 6 John T. Patton, Indiana University, USA How Rotaviruses Do It? RNA Synthesis in Double-Stranded RNA Viruses
Tuesday, May 03 \| 5:00PM - 7:00PM Replication Enzymes and Other Factors Room: Zilker 3-4 Both viral and cellular proteins and RNAs catalyzing the formation of RNA progeny. Speaker 5 of 6 Tero Ahola, University of Helsinki, Finland Short Talk: There is One Defined Pathway for Alphavirus RNA Replication
Tuesday, May 03 \| 5:00PM - 7:00PM Replication Enzymes and Other Factors Room: Zilker 3-4 Both viral and cellular proteins and RNAs catalyzing the formation of RNA progeny. Speaker 6 of 6 Eric Poeschla, University of Colorado School of Medicine, USA Short Talk: Broad Spectrum Antiviral Protection via Positive Strand RNA Virus RdRp-Mediated Stable Activation of RIG-I-Like Receptor-dependent Innate Immunity
Tuesday, May 03 \| 7:00PM - 7:00PM On Own for Dinner
Wednesday, May 04 \| 7:30AM - 8:30AM Breakfast Room: Zilker 1-2
Wednesday, May 04 \| 8:30AM - 11:30AM Virus Modulations of Host Pathways Room: Zilker 3-4 Host-virus interactions. Speaker 1 of 7 * Ralf Bartenschlager, Heidelberg University, Germany
Wednesday, May 04 \| 8:30AM - 11:30AM Virus Modulations of Host Pathways Room: Zilker 3-4 Host-virus interactions. Speaker 2 of 7 Peter D. Nagy, University of Kentucky, USA Tombusvirus Replicase Complex Usurps the Glycolytic Pathway for Robust Replication
Wednesday, May 04 \| 8:30AM - 11:30AM Virus Modulations of Host Pathways Room: Zilker 3-4 Host-virus interactions. Speaker 3 of 7 Sean P. Whelan, Harvard Medical School, USA VSV Polymerase Architecture and Activity Regulated by Host Cell Factors
Wednesday, May 04 \| 8:30AM - 11:30AM Virus Modulations of Host Pathways Room: Zilker 3-4 Host-virus interactions. Speaker 4 of 7 William Jackson, University of Maryland School of Medicine, USA Short Talk: A Novel Signaling Mechanism Induces Autophagy in Poliovirus-Infected Cells
Wednesday, May 04 \| 8:30AM - 11:30AM Virus Modulations of Host Pathways Room: Zilker 3-4 Host-virus interactions. Speaker 5 of 7 Karla A. Kirkegaard, Stanford University School of Medicine, USA Noncoding RNAs and Virus Infection
Wednesday, May 04 \| 8:30AM - 11:30AM Virus Modulations of Host Pathways Room: Zilker 3-4 Host-virus interactions. Speaker 6 of 7 Michael Gale, Jr., University of Washington, USA Pathogen Sensing and Response in RNA Virus Infection
Wednesday, May 04 \| 8:30AM - 11:30AM Virus Modulations of Host Pathways Room: Zilker 3-4 Host-virus interactions. Speaker 7 of 7 Tristan X. Jordan, University of Chicago, USA Short Talk: AMPK Inhibition of mTOR Activity is Required for Dengue Virus-Induced Lipophagy
Wednesday, May 04 \| 9:50AM - 10:10AM Coffee Break Room: Zilker North Lobby
Wednesday, May 04 \| 11:30AM - 5:00PM On Own for Lunch
Wednesday, May 04 \| 11:30AM - 1:00PM Poster Setup Room: Zilker 1-2
Wednesday, May 04 \| 1:00PM - 10:00PM Poster Viewing Room: Zilker 1-2
Wednesday, May 04 \| 2:30PM - 4:30PM Workshop 2: Emerging Concepts and Landscapes Room: Zilker 3-4 Speaker 1 of 9 * Eva Harris, Division of Infectious Diseases and Vaccinology, School of Public Health, USA
Wednesday, May 04 \| 2:30PM - 4:30PM Workshop 2: Emerging Concepts and Landscapes Room: Zilker 3-4 Speaker 2 of 9 Craig B. Wilen, Washington University, USA Discovery of a Proteinaceous Cellular Receptor for a Norovirus
Wednesday, May 04 \| 2:30PM - 4:30PM Workshop 2: Emerging Concepts and Landscapes Room: Zilker 3-4 Speaker 3 of 9 Sue E. Crawford, Baylor College of Medicine, USA Human Noroviruses Replicate in Stem-cell Derived Human Intestinal Enteroids
Wednesday, May 04 \| 2:30PM - 4:30PM Workshop 2: Emerging Concepts and Landscapes Room: Zilker 3-4 Speaker 4 of 9 Jason Mackenzie, University of Melbourne, Australia Norovirus Translation: Control at the Stress Granule-PKR-p-elf2Alpha axis
Wednesday, May 04 \| 2:30PM - 4:30PM Workshop 2: Emerging Concepts and Landscapes Room: Zilker 3-4 Speaker 5 of 9 Alexandra Schafer, University of North Carolina at Chapel Hill, USA The Epigenetic Landscape during MERS-CoV Infection
Wednesday, May 04 \| 2:30PM - 4:30PM Workshop 2: Emerging Concepts and Landscapes Room: Zilker 3-4 Speaker 6 of 9 Mohsan Saeed, Rockefeller University, USA Development of an Efficient Pan-Genotype Cell Culture System for Hepatitis C Virus
Wednesday, May 04 \| 2:30PM - 4:30PM Workshop 2: Emerging Concepts and Landscapes Room: Zilker 3-4 Speaker 7 of 9 Ann Palmenberg, University of Wisconsin-Madison, USA Atomic Resolution Structures of Rhinovirus C15a by Cryo-EM Show Unique Topographies and Virion Properties
Wednesday, May 04 \| 2:30PM - 4:30PM Workshop 2: Emerging Concepts and Landscapes Room: Zilker 3-4 Speaker 8 of 9 Jessica L. Smith, Oregon Health and Sciences University, USA A microRNA Screen Identifies the miR-34 Family as Potent Inhibitors of Flavivirus Infection and Reveals an Intersection Between the Wnt and Interferon Signaling Pathways
Wednesday, May 04 \| 2:30PM - 4:30PM Workshop 2: Emerging Concepts and Landscapes Room: Zilker 3-4 Speaker 9 of 9 Shangmei Hou, University of Alberta, Canada Flavivirus Infection Impairs Peroxisome Biogenesis and Early Anti-Viral Signaling
Wednesday, May 04 \| 4:30PM - 5:00PM Coffee Available Room: Zilker North Lobby
Wednesday, May 04 \| 5:00PM - 7:15PM Evolution, Adaptation and Virus Fitness Room: Zilker 3-4 Experimental and theoretical approaches to understanding mechanisms of virus evolution. Speaker 1 of 6 * Craig E. Cameron, UNC School of Medicine, USA
Wednesday, May 04 \| 5:00PM - 7:15PM Evolution, Adaptation and Virus Fitness Room: Zilker 3-4 Experimental and theoretical approaches to understanding mechanisms of virus evolution. Speaker 2 of 6 Claus Wilke, University of Texas at Austin, USA Next-Gen Virology: Use of Microfluidics and Live-Cell Imaging to Study Poliovirus Replication at the Single-Cell Level
Wednesday, May 04 \| 5:00PM - 7:15PM Evolution, Adaptation and Virus Fitness Room: Zilker 3-4 Experimental and theoretical approaches to understanding mechanisms of virus evolution. Speaker 3 of 6 Paul E. Turner, Yale University, USA Rate of Novel Host Invasion affects Adaptability of Evolving RNA Virus Lineages
Wednesday, May 04 \| 5:00PM - 7:15PM Evolution, Adaptation and Virus Fitness Room: Zilker 3-4 Experimental and theoretical approaches to understanding mechanisms of virus evolution. Speaker 4 of 6 Raul Andino, University of California, San Francisco, USA RNA Virus Population Dynamics and the Mechanisms of Adaptation
Wednesday, May 04 \| 5:00PM - 7:15PM Evolution, Adaptation and Virus Fitness Room: Zilker 3-4 Experimental and theoretical approaches to understanding mechanisms of virus evolution. Speaker 5 of 6 Johan Neyts, University of Leuven, Belgium Towards Antivirals against Flavi-, Picorna-, Alpha- and Noroviruses
Wednesday, May 04 \| 5:00PM - 7:15PM Evolution, Adaptation and Virus Fitness Room: Zilker 3-4 Experimental and theoretical approaches to understanding mechanisms of virus evolution. Speaker 6 of 6 Mark R. Denison, Vanderbilt University Medical Center, USA Short Talk: Identification of Coronavirus Fidelity Determinants Following Long-Term Passage of Murine Hepatitis Virus Lacking nsp14-ExoN Mediated Fidelity
Wednesday, May 04 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Zilker 1-2 No registration fees are used to fund alcohol served at this function.
Wednesday, May 04 \| 7:30PM - 10:00PM Poster Session 3 Room: Zilker 1-2
Thursday, May 05 \| 7:30AM - 8:30AM Breakfast Room: Zilker 1-2
Thursday, May 05 \| 8:30AM - 11:30AM Immunity and Stress Responses Room: Zilker 3-4 Virus are under pressure to replicate and in doing so cell host detect them inducing innate immunity. Is stress involved in the process? How viruses deal with stress and innate immunity responses? Speaker 1 of 7 * Michael Gale, Jr., University of Washington, USA
Thursday, May 05 \| 8:30AM - 11:30AM Immunity and Stress Responses Room: Zilker 3-4 Virus are under pressure to replicate and in doing so cell host detect them inducing innate immunity. Is stress involved in the process? How viruses deal with stress and innate immunity responses? Speaker 2 of 7 Ana Fernandez-Sesma, Icahn School of Medicine at Mount Sinai, USA Innate Immunity to Dengue Virus
Thursday, May 05 \| 8:30AM - 11:30AM Immunity and Stress Responses Room: Zilker 3-4 Virus are under pressure to replicate and in doing so cell host detect them inducing innate immunity. Is stress involved in the process? How viruses deal with stress and innate immunity responses? Speaker 3 of 7 Nihal Altan-Bonnet, NHLBI, National Institutes of Health, USA Intercellular Transmission of Viral Populations with Vesicles
Thursday, May 05 \| 8:30AM - 11:30AM Immunity and Stress Responses Room: Zilker 3-4 Virus are under pressure to replicate and in doing so cell host detect them inducing innate immunity. Is stress involved in the process? How viruses deal with stress and innate immunity responses? Speaker 4 of 7 Scott Benjamin Biering, University of Chicago, USA Short Talk: Replication Complexes of Positive-Strand RNA Viruses are Disrupted by Interferon-Gamma Inducible GTPases
Thursday, May 05 \| 8:30AM - 11:30AM Immunity and Stress Responses Room: Zilker 3-4 Virus are under pressure to replicate and in doing so cell host detect them inducing innate immunity. Is stress involved in the process? How viruses deal with stress and innate immunity responses? Speaker 5 of 7 Richard E. Lloyd, Baylor College of Medicine, USA Enterovirus Antagonism of RNA Granules
Thursday, May 05 \| 8:30AM - 11:30AM Immunity and Stress Responses Room: Zilker 3-4 Virus are under pressure to replicate and in doing so cell host detect them inducing innate immunity. Is stress involved in the process? How viruses deal with stress and innate immunity responses? Speaker 6 of 7 Maria-Carla Saleh, Institut Pasteur, France Systemic Spread of Antiviral RNAi Immunity through Extracellular Vesicles Containing Viral RNAs
Thursday, May 05 \| 8:30AM - 11:30AM Immunity and Stress Responses Room: Zilker 3-4 Virus are under pressure to replicate and in doing so cell host detect them inducing innate immunity. Is stress involved in the process? How viruses deal with stress and innate immunity responses? Speaker 7 of 7 Eva Harris, Division of Infectious Diseases and Vaccinology, School of Public Health, USA Short Talk: Mechanisms of Dengue Virus NS1-Induced Endothelial Permeability and Vascular Leak
Thursday, May 05 \| 9:50AM - 10:10AM Coffee Break Room: Zilker North Lobby
Thursday, May 05 \| 11:30AM - 5:00PM On Own for Lunch
Thursday, May 05 \| 3:00PM - 4:30PM Workshop 3: Discussion on the Emergence of ZIKA Virus and Ot her Flaviviruses Room: Zilker 3-4 Speaker 1 of 6 * Michael S. Diamond, Washington University School of Medicine, USA
Thursday, May 05 \| 3:00PM - 4:30PM Workshop 3: Discussion on the Emergence of ZIKA Virus and Ot her Flaviviruses Room: Zilker 3-4 Speaker 2 of 6 Nicholas Barrows, Duke University, USA Repurposed Drug Candidates to Treat Zika Virus Infection in Pregnancy
Thursday, May 05 \| 3:00PM - 4:30PM Workshop 3: Discussion on the Emergence of ZIKA Virus and Ot her Flaviviruses Room: Zilker 3-4 Speaker 3 of 6 Bryan C. Mounce, Institut Pasteur, France Interferon-induced Spermidine-spermine N1-Acetyltransferase and Polyamine Depletion Restrict Chikungunya and Zika Virus Transcription and Translation
Thursday, May 05 \| 3:00PM - 4:30PM Workshop 3: Discussion on the Emergence of ZIKA Virus and Ot her Flaviviruses Room: Zilker 3-4 Speaker 4 of 6 Hengli Tang, Florida State University, USA Zika Virus Infection Leads to Cell Cycle Arrest and Stunted Growth of Human Cortical Neural Progenitors
Thursday, May 05 \| 3:00PM - 4:30PM Workshop 3: Discussion on the Emergence of ZIKA Virus and Ot her Flaviviruses Room: Zilker 3-4 Speaker 5 of 6 Douglas G. Widman, University of North Carolina at Chapel Hill, USA A Reverse Genetics Platform to Generate Zika Virus Infectious Clones and Evaluate Viral Determinants of Pathogenesis
Thursday, May 05 \| 3:00PM - 4:30PM Workshop 3: Discussion on the Emergence of ZIKA Virus and Ot her Flaviviruses Room: Zilker 3-4 Speaker 6 of 6 Devika Sirohi, Purdue University, USA The Cryo-EM Structure of Zika Virus
Thursday, May 05 \| 4:30PM - 5:00PM Coffee Available Room: Zilker North Lobby
Thursday, May 05 \| 5:00PM - 6:45PM Therapeutic Interventions Room: Zilker 3-4 Novel interventions targeting virus and host factors. Speaker 1 of 5 * Maria-Carla Saleh, Institut Pasteur, France
Thursday, May 05 \| 5:00PM - 6:45PM Therapeutic Interventions Room: Zilker 3-4 Novel interventions targeting virus and host factors. Speaker 2 of 5 Judith Frydman, Stanford University, USA Host Protein Homeostasis Machinery as an Antiviral Target
Thursday, May 05 \| 5:00PM - 6:45PM Therapeutic Interventions Room: Zilker 3-4 Novel interventions targeting virus and host factors. Speaker 3 of 5 Susan C. Baker, Loyola University Chicago, USA Targeting Coronavirus Papain-like Proteases to Block Viral Replication and Pathogenesis
Thursday, May 05 \| 5:00PM - 6:45PM Therapeutic Interventions Room: Zilker 3-4 Novel interventions targeting virus and host factors. Speaker 4 of 5 Matthew Frieman, University of Maryland, USA Short Talk: Identification and Characterization of ABL Kinase Inhibitors as Potent Inhibitors of SARS-CoV and MERS-CoV Fusion
Thursday, May 05 \| 5:00PM - 6:45PM Therapeutic Interventions Room: Zilker 3-4 Novel interventions targeting virus and host factors. Speaker 5 of 5 Ying Kai Chan, Harvard Medical School, USA Short Talk: Dengue Virus NS3 Antagonizes Innate Immunity Using a Phosphomimetic-Based Mechanism
Thursday, May 05 \| 6:45PM - 7:00PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Room: Zilker 3-4
Thursday, May 05 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Zilker 1-2 No registration fees are used to fund alcohol served at this function.
Thursday, May 05 \| 8:00PM - 11:00PM Entertainment Room: Zilker 1-2 Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
Thursday, May 05 \| 8:00PM - 11:00PM Cash Bar Room: Zilker 1-2
Friday, May 06 \| 10:25AM - 10:25AM Departure *Session Chair.