Web Desc
The Cancer Genome
joint with Genomics and Personalized Medicine
Organizer(s): Elaine R. Mardis, Sohrab Shah and Ben J. Raphael
Date: February 07 - 11, 2016
Location: Fairmont Banff Springs, Banff, AB, Canada
Sponsored by Constellation Pharmaceuticals, Incyte Corporation and Roche
Summary of Meeting:
The combination of next-generation sequencing and analysis as applied to experiments studying the cancer genome has revolutionized our understanding of cancer biology. Large-scale cancer genomics has further established a baseline that is now poised to effect the translation of cancer genomics into the clinical setting, effectively transforming patient care. The barriers and challenges to translation are significant, not the least of which involves the transition of research-grade computational and interpretational analysis to clinical-grade analysis. Assays must be highly refined, validated and accurate. How the use of genomic approaches to monitor patient response to therapy, the onset of acquired resistance to therapy and other aspects of patient care will be accepted as a more sensitive partner with conventional imaging approaches must be addressed. Appropriate assignment of therapies to specific gene/protein alterations also will be of paramount importance, especially as the numbers and types of targeted therapies increase. Genomics will also impact our understanding of the immune system's interaction with tumors, leading to the development of personalized vaccine strategies that may provide more durable responses. Specific goals of the meeting include: 1) Providing an overview of computational tools, any gaps in variant detection capabilities and their challenges for clinical implementation; 2) Discussing specific approaches to identify gene-therapy combinations, specifically addressing the difficulty of assessing the impact of DNA mutations on protein function; 3) Identification of the significant efforts ongoing in blood-based ('liquid') biopsy of patients on therapy or following resection surgery; 4) Presentation of current efforts to utilize genomics of individual tumors to inform immunotherapy development; 5) Discussion of efforts at data integration, across 'omic' platforms, and also the integration of genomic data with more conventional pathology-based evidence/data. The anticipated outcomes will be the exchange of ideas among international participants on how genomics will impact cancer care and clinical practice and what gaps exist in their existing approaches, as well as development of new collaborations and new enthusiasm for helping to build on the potential of genome-guided approaches to cancer medicine.
Scholarship Deadline: October 7 2015
Discounted Abstract Deadline: October 7 2015
Abstract Deadline: November 9 2015
Discounted Registration Deadline: December 7 2015
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Constellation PharmaceuticalsIncyte CorporationRoche
We gratefully acknowledge additional support for this conference from:
Abcam plcExiqon A/S
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, February 07 | 4:00PM - 8:00PM
Arrival and Registration
Room: Van Horne Foyer


Sunday, February 07 | 6:00PM - 8:00PM
Welcome Mixer
Room: Van Horne Foyer
No registration fees are used to fund alcohol served at this function.

Monday, February 08 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Monday, February 08 | 8:00AM - 9:30AM
Welcome and Keynote Session (Joint)
Room: Van Horne A/B

Speaker 1 of 4
* Elaine R. Mardis, Nationwide Children's Hospital, USA

Monday, February 08 | 8:00AM - 9:30AM
Welcome and Keynote Session (Joint)
Room: Van Horne A/B

Speaker 2 of 4
* Michael P. Snyder, Stanford University School of Medicine, USA

Monday, February 08 | 8:00AM - 9:30AM
Welcome and Keynote Session (Joint)
Room: Van Horne A/B

Speaker 3 of 4
Levi A. Garraway, Genentech, Inc, USA
Sequencing and Clinical Interpretation to Guide Precision Cancer Medicine

Monday, February 08 | 8:00AM - 9:30AM
Welcome and Keynote Session (Joint)
Room: Van Horne A/B

Speaker 4 of 4
James P. Allison, University of Texas MD Anderson Cancer Center, USA
Blockade Therapies: Current Experience and Future Directions

Monday, February 08 | 9:30AM - 9:50AM
Coffee Break
Room: Van Horne Foyer


Monday, February 08 | 9:50AM - 11:30AM
Cancer Genomics: Discovery to Translation (Joint)
Room: Van Horne A/B

Speaker 1 of 5
* Michael P. Snyder, Stanford University School of Medicine, USA

Monday, February 08 | 9:50AM - 11:30AM
Cancer Genomics: Discovery to Translation (Joint)
Room: Van Horne A/B

Speaker 2 of 5
* Elaine R. Mardis, Nationwide Children's Hospital, USA
Clinical Translation of Cancer Genomics

Monday, February 08 | 9:50AM - 11:30AM
Cancer Genomics: Discovery to Translation (Joint)
Room: Van Horne A/B

Speaker 3 of 5
David Solit, Memorial Sloan Kettering Cancer Center, USA
Defining the Actionable Genome

Monday, February 08 | 9:50AM - 11:30AM
Cancer Genomics: Discovery to Translation (Joint)
Room: Van Horne A/B

Speaker 4 of 5
Heidi Greulich, Broad Institute of MIT and Harvard, USA
Short Talk: Identification of a Novel Cell-Selective Anti-Cancer Modulator of PDE3A by Predictive Chemogenomics

Monday, February 08 | 9:50AM - 11:30AM
Cancer Genomics: Discovery to Translation (Joint)
Room: Van Horne A/B

Speaker 5 of 5
Nolan Priedigkeit, University of Pittsburgh, USA
Short Talk: Transcriptomic Evolution of Fusion Genes in Recurrent Ovarian Cancer

Monday, February 08 | 11:30AM - 1:00PM
Poster Setup
Room: Mezzanine 2


Monday, February 08 | 11:30AM - 2:30PM
On Own for Lunch


Monday, February 08 | 1:00PM - 10:00PM
Poster Viewing
Room: Mezzanine 2


Monday, February 08 | 2:30PM - 4:30PM
Panel: Challenges of Precision Oncology in the Clinical Sett
ing (Joint)
Room: Van Horne A/B

Speaker 1 of 4
Levi A. Garraway, Genentech, Inc, USA

Monday, February 08 | 2:30PM - 4:30PM
Panel: Challenges of Precision Oncology in the Clinical Sett
ing (Joint)
Room: Van Horne A/B

Speaker 2 of 4
Lillian L. Siu, Princess Margaret Hospital, Canada

Monday, February 08 | 2:30PM - 4:30PM
Panel: Challenges of Precision Oncology in the Clinical Sett
ing (Joint)
Room: Van Horne A/B

Speaker 3 of 4
Michael F. Berger, Memorial Sloan Kettering Cancer Center, USA

Monday, February 08 | 2:30PM - 4:30PM
Panel: Challenges of Precision Oncology in the Clinical Sett
ing (Joint)
Room: Van Horne A/B

Speaker 4 of 4
David Hyman, Memorial Sloan Kettering Cancer Center, USA

Monday, February 08 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Monday, February 08 | 5:00PM - 7:00PM
Genome-Guided Cancer Therapy
Room: Van Horne A/B

Speaker 1 of 5
* Alexandra Snyder, Merck, USA

Monday, February 08 | 5:00PM - 7:00PM
Genome-Guided Cancer Therapy
Room: Van Horne A/B

Speaker 2 of 5
Lillian L. Siu, Princess Margaret Hospital, Canada
Experience from Princess Margaret IMPACT/COMPACT Trial

Monday, February 08 | 5:00PM - 7:00PM
Genome-Guided Cancer Therapy
Room: Van Horne A/B

Speaker 3 of 5
Nuria Lopez-Bigas, University Pompeu Fabra - UPF, Spain
Cancer Drivers and their Therapeutic Opportunities

Monday, February 08 | 5:00PM - 7:00PM
Genome-Guided Cancer Therapy
Room: Van Horne A/B

Speaker 4 of 5
Andrew V. Biankin, University of Glasgow, UK
Talk Title to be Announced

Monday, February 08 | 5:00PM - 7:00PM
Genome-Guided Cancer Therapy
Room: Van Horne A/B

Speaker 5 of 5
Xuan Shirley Li, MolecularMatch, Inc, USA
Short Talk: The MolecularMatch Genotype Based Therapeutics and Clinical Trials Search Engine

Monday, February 08 | 5:00PM - 7:00PM
Disease Gene Discovery
This session is from Personalized Medicine
Room: Van Horne C

Speaker 1 of 5
* Heidi Rehm, Harvard Medical School, USA


Monday, February 08 | 5:00PM - 7:00PM
Disease Gene Discovery
This session is from Personalized Medicine
Room: Van Horne C

Speaker 2 of 5
Karen B. Avraham, Tel Aviv University, Israel
Genomics of Hereditary Deafness


Monday, February 08 | 5:00PM - 7:00PM
Disease Gene Discovery
This session is from Personalized Medicine
Room: Van Horne C

Speaker 3 of 5
Joseph G. Gleeson, HHMI/The Rockefeller University, USA
Genomics and Precision Medicine in Neurodevelopmental Disease


Monday, February 08 | 5:00PM - 7:00PM
Disease Gene Discovery
This session is from Personalized Medicine
Room: Van Horne C

Speaker 4 of 5
Richard A. Gibbs, Baylor College of Medicine, USA
Expanding the Mendelian View


Monday, February 08 | 5:00PM - 7:00PM
Disease Gene Discovery
This session is from Personalized Medicine
Room: Van Horne C

Speaker 5 of 5
Ana S.A. Cohen, University of British Columbia, Canada
Short Talk: Exome Sequencing of Patients with Weaver-Like Features Links Another Cancer Gene, EED, to Overgrowth Syndromes


Monday, February 08 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mezzanine 2
No registration fees are used to fund alcohol served at this function.

Monday, February 08 | 7:30PM - 10:00PM
Poster Session 1
Room: Mezzanine 2


Tuesday, February 09 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Tuesday, February 09 | 8:00AM - 11:00AM
Genomics Informs Personalized Immunotherapy
Room: Van Horne A/B

Speaker 1 of 6
* James P. Allison, University of Texas MD Anderson Cancer Center, USA

Tuesday, February 09 | 8:00AM - 11:00AM
Genomics Informs Personalized Immunotherapy
Room: Van Horne A/B

Speaker 2 of 6
Robert D. Schreiber, Washington University School of Medicine, USA
Genomic Approaches to Understand Cancer Immunosuppression

Tuesday, February 09 | 8:00AM - 11:00AM
Genomics Informs Personalized Immunotherapy
Room: Van Horne A/B

Speaker 3 of 6
Renier Brentjens, Memorial Sloan Kettering Cancer Center, USA
Moving CAR T Cell Therapy Forward: CARs and Armored CARs

Tuesday, February 09 | 8:00AM - 11:00AM
Genomics Informs Personalized Immunotherapy
Room: Van Horne A/B

Speaker 4 of 6
Alexandra Snyder, Merck, USA
Beyond Mutational Load in Checkpoint Blockade Therapies and Advanced Solid Tumors

Tuesday, February 09 | 8:00AM - 11:00AM
Genomics Informs Personalized Immunotherapy
Room: Van Horne A/B

Speaker 5 of 6
Magali C. Champion, Stanford University, USA
Short Talk: Pancancer Module Analysis Captures Major Oncogenic Pathways and Identifies Master Regulator of Immune Response

Tuesday, February 09 | 8:00AM - 11:00AM
Genomics Informs Personalized Immunotherapy
Room: Van Horne A/B

Speaker 6 of 6
Haven Garber, University of Texas MD Anderson Cancer Center, USA
Short Talk: Subclonal Evolution of Chronic Lymphocytic Leukemia (CLL) after Allogeneic T-cell Immunotherapies

Tuesday, February 09 | 8:00AM - 11:15AM
Technology and Sensors
This session is from Personalized Medicine
Room: Van Horne C

Speaker 1 of 7
* Leroy E. Hood, Institute for Systems Biology, USA


Tuesday, February 09 | 8:00AM - 11:15AM
Technology and Sensors
This session is from Personalized Medicine
Room: Van Horne C

Speaker 2 of 7
William J. Greenleaf, Stanford University, USA
Single Cell ATAC-Seq


Tuesday, February 09 | 8:00AM - 11:15AM
Technology and Sensors
This session is from Personalized Medicine
Room: Van Horne C

Speaker 3 of 7
Ali Torkamani, The Scripps Translational Science Institute & Scripps Research Institute, USA
Genome-Guided Therapy Repurposing and Response Monitoring in Orphan Disease


Tuesday, February 09 | 8:00AM - 11:15AM
Technology and Sensors
This session is from Personalized Medicine
Room: Van Horne C

Speaker 4 of 7
Jim R. Heath, California Institute of Technology, USA
Affinity Reagents and Sensors


Tuesday, February 09 | 8:00AM - 11:15AM
Technology and Sensors
This session is from Personalized Medicine
Room: Van Horne C

Speaker 5 of 7
Lars M. Steinmetz, European Molecular Biology Laboratory and Stanford University, Germany
Biosensors for Personal Molecular Monitoring of Health and Disease


Tuesday, February 09 | 8:00AM - 11:15AM
Technology and Sensors
This session is from Personalized Medicine
Room: Van Horne C

Speaker 6 of 7
Shengxi Guan, New England Biolabs, USA
Short Talk: A Sensitive Approach to Map Genome-wide 5-Hydroxymethylcytosine and 5-Formylcytosine at Single-Base Resolution


Tuesday, February 09 | 8:00AM - 11:15AM
Technology and Sensors
This session is from Personalized Medicine
Room: Van Horne C

Speaker 7 of 7
Carla Grandori, SEngine Precision Medicine and Cure First, USA
Short Talk: Cross-Cancer Target Identification and Validation through Synthetic Lethality, TCGA Analysis, and Patient Sample Screening


Tuesday, February 09 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Tuesday, February 09 | 11:00AM - 2:30PM
On Own for Lunch


Tuesday, February 09 | 2:30PM - 4:30PM
Workshop: The Integrative Human Microbiome Project (iHMP): D
ynamic Analysis of Microbiome-Host Omics Profiles during Periods of Human Health and Disease (Joint)
Room: Van Horne A/B
The Integrative Human Microbiome Project (iHMP) is the second phase of the National Institute of Health (NIH) Common Fund's Human Microbiome Project (HMP) program. The mission of the overall HMP is to generate resources to permit comprehensive characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease. In this phase of the program, the iHMP is creating integrated longitudinal datasets of biological properties from both the microbiome and host from three different cohort studies of microbiome-associated conditions using multiple 'omics' technologies. Tools, datasets and other resources from the first phase of the project are available at the HMP DACC. During this session, we will provide an overview of the data and resources freely available to the research community as derived from the three iHMP projects: 1) the Multi-Omic Microbiome Study: Pregnancy Initiative (MOMS-PI) at Virginia Commonwealth University, 2) the Inflammatory Bowel Disease Multi'omic Data (IBDMDB) resource from the Broad Institute and a nation-wide research tam, and 3) Integrated Personal 'Omics Profiling (IPOP) from Stanford University and the Jackson Laboratory for Genomic Medicine. For more information or to get involved with the iHMP, please see http://hmp2.org.
Speaker 1 of 4
* Curtis Huttenhower, Harvard School of Public Health, USA

Tuesday, February 09 | 2:30PM - 4:30PM
Workshop: The Integrative Human Microbiome Project (iHMP): D
ynamic Analysis of Microbiome-Host Omics Profiles during Periods of Human Health and Disease (Joint)
Room: Van Horne A/B
The Integrative Human Microbiome Project (iHMP) is the second phase of the National Institute of Health (NIH) Common Fund's Human Microbiome Project (HMP) program. The mission of the overall HMP is to generate resources to permit comprehensive characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease. In this phase of the program, the iHMP is creating integrated longitudinal datasets of biological properties from both the microbiome and host from three different cohort studies of microbiome-associated conditions using multiple 'omics' technologies. Tools, datasets and other resources from the first phase of the project are available at the HMP DACC. During this session, we will provide an overview of the data and resources freely available to the research community as derived from the three iHMP projects: 1) the Multi-Omic Microbiome Study: Pregnancy Initiative (MOMS-PI) at Virginia Commonwealth University, 2) the Inflammatory Bowel Disease Multi'omic Data (IBDMDB) resource from the Broad Institute and a nation-wide research tam, and 3) Integrated Personal 'Omics Profiling (IPOP) from Stanford University and the Jackson Laboratory for Genomic Medicine. For more information or to get involved with the iHMP, please see http://hmp2.org.
Speaker 2 of 4
Anup Mahurkar, University of Maryland Baltimore, USA

Tuesday, February 09 | 2:30PM - 4:30PM
Workshop: The Integrative Human Microbiome Project (iHMP): D
ynamic Analysis of Microbiome-Host Omics Profiles during Periods of Human Health and Disease (Joint)
Room: Van Horne A/B
The Integrative Human Microbiome Project (iHMP) is the second phase of the National Institute of Health (NIH) Common Fund's Human Microbiome Project (HMP) program. The mission of the overall HMP is to generate resources to permit comprehensive characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease. In this phase of the program, the iHMP is creating integrated longitudinal datasets of biological properties from both the microbiome and host from three different cohort studies of microbiome-associated conditions using multiple 'omics' technologies. Tools, datasets and other resources from the first phase of the project are available at the HMP DACC. During this session, we will provide an overview of the data and resources freely available to the research community as derived from the three iHMP projects: 1) the Multi-Omic Microbiome Study: Pregnancy Initiative (MOMS-PI) at Virginia Commonwealth University, 2) the Inflammatory Bowel Disease Multi'omic Data (IBDMDB) resource from the Broad Institute and a nation-wide research tam, and 3) Integrated Personal 'Omics Profiling (IPOP) from Stanford University and the Jackson Laboratory for Genomic Medicine. For more information or to get involved with the iHMP, please see http://hmp2.org.
Speaker 3 of 4
Liang Liang, Stanford University, USA

Tuesday, February 09 | 2:30PM - 4:30PM
Workshop: The Integrative Human Microbiome Project (iHMP): D
ynamic Analysis of Microbiome-Host Omics Profiles during Periods of Human Health and Disease (Joint)
Room: Van Horne A/B
The Integrative Human Microbiome Project (iHMP) is the second phase of the National Institute of Health (NIH) Common Fund's Human Microbiome Project (HMP) program. The mission of the overall HMP is to generate resources to permit comprehensive characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease. In this phase of the program, the iHMP is creating integrated longitudinal datasets of biological properties from both the microbiome and host from three different cohort studies of microbiome-associated conditions using multiple 'omics' technologies. Tools, datasets and other resources from the first phase of the project are available at the HMP DACC. During this session, we will provide an overview of the data and resources freely available to the research community as derived from the three iHMP projects: 1) the Multi-Omic Microbiome Study: Pregnancy Initiative (MOMS-PI) at Virginia Commonwealth University, 2) the Inflammatory Bowel Disease Multi'omic Data (IBDMDB) resource from the Broad Institute and a nation-wide research tam, and 3) Integrated Personal 'Omics Profiling (IPOP) from Stanford University and the Jackson Laboratory for Genomic Medicine. For more information or to get involved with the iHMP, please see http://hmp2.org.
Speaker 4 of 4
James P. Brooks, Virginia Commonwealth University, USA

Tuesday, February 09 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Tuesday, February 09 | 5:00PM - 7:15PM
Personal Medicine and Health (Joint)
Room: Van Horne A/B

Speaker 1 of 6
* Diana W. Bianchi, NICHD, National Institutes of Health, USA

Tuesday, February 09 | 5:00PM - 7:15PM
Personal Medicine and Health (Joint)
Room: Van Horne A/B

Speaker 2 of 6
Leroy E. Hood, Institute for Systems Biology, USA
Systems Medicine and Proactive P4 Medicine: Transforming Healthcare through Wellness—A Personal View

Tuesday, February 09 | 5:00PM - 7:15PM
Personal Medicine and Health (Joint)
Room: Van Horne A/B

Speaker 3 of 6
Heidi Rehm, Harvard Medical School, USA
Supporting Genomic Interpretation

Tuesday, February 09 | 5:00PM - 7:15PM
Personal Medicine and Health (Joint)
Room: Van Horne A/B

Speaker 4 of 6
Larry Norton, Memorial Sloan Kettering Cancer Center, USA
BCRF Funded Sequencing of Metastatic Breast Cancers

Tuesday, February 09 | 5:00PM - 7:15PM
Personal Medicine and Health (Joint)
Room: Van Horne A/B

Speaker 5 of 6
Mark Basik, McGill University, Canada
Short Talk: The DNA Landscape of Drug-resistant Triple Negative Breast Cancer

Tuesday, February 09 | 5:00PM - 7:15PM
Personal Medicine and Health (Joint)
Room: Van Horne A/B

Speaker 6 of 6
Haiyuan Yu, Cornell University, USA
Short Talk: Precision Medicine through 3D Interactome Models and Network Perturbation Studies

Tuesday, February 09 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Mezzanine 2
No registration fees are used to fund alcohol served at this function.

Wednesday, February 10 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Wednesday, February 10 | 8:00AM - 11:15AM
Emerging Themes in Cancer Genomics
Room: Van Horne A/B

Speaker 1 of 6
* Sohrab Shah, Memorial Sloan Kettering Cancer Center, USA

Wednesday, February 10 | 8:00AM - 11:15AM
Emerging Themes in Cancer Genomics
Room: Van Horne A/B

Speaker 2 of 6
Arul M. Chinnaiyan, University of Michigan, USA
Molecular Tumor Board at UMichigan: Progress and Impact

Wednesday, February 10 | 8:00AM - 11:15AM
Emerging Themes in Cancer Genomics
Room: Van Horne A/B

Speaker 3 of 6
Jeff Tyner, Oregon Health & Science University, USA
Combining Genomic and Functional Screening in Targeted Therapy Decision-Making

Wednesday, February 10 | 8:00AM - 11:15AM
Emerging Themes in Cancer Genomics
Room: Van Horne A/B

Speaker 4 of 6
Michael F. Berger, Memorial Sloan Kettering Cancer Center, USA
Matching Patients to Treatments through Enterprise-Wide Tumor Sequencing

Wednesday, February 10 | 8:00AM - 11:15AM
Emerging Themes in Cancer Genomics
Room: Van Horne A/B

Speaker 5 of 6
Marco A. Marra, British Columbia Cancer Agency, Canada
The BC Cancer Agency Personalized OncoGenomics (POG) Project

Wednesday, February 10 | 8:00AM - 11:15AM
Emerging Themes in Cancer Genomics
Room: Van Horne A/B

Speaker 6 of 6
David Hyman, Memorial Sloan Kettering Cancer Center, USA
New Precision Medicine Clinical Trial Paradigms, Leveraging Cancer Genomics in the Clinic

Wednesday, February 10 | 8:00AM - 11:15AM
Personalized and Preventative Medicine
This session is from Personalized Medicine
Room: Van Horne C

Speaker 1 of 7
* Karen B. Avraham, Tel Aviv University, Israel


Wednesday, February 10 | 8:00AM - 11:15AM
Personalized and Preventative Medicine
This session is from Personalized Medicine
Room: Van Horne C

Speaker 2 of 7
Robert C. Green, Harvard Medical School/Brigham and Women’s Hospital, USA
Medical, Behavioral and Economic Outcomes in Genomic Medicine


Wednesday, February 10 | 8:00AM - 11:15AM
Personalized and Preventative Medicine
This session is from Personalized Medicine
Room: Van Horne C

Speaker 3 of 7
Dennis Wall, Stanford University, USA
Initial Findings from the Whole Genome Sequencing of 3000 Individuals in Multiplex Autism Families


Wednesday, February 10 | 8:00AM - 11:15AM
Personalized and Preventative Medicine
This session is from Personalized Medicine
Room: Van Horne C

Speaker 4 of 7
David R. Walt, Tufts University, USA
Single Molecules and Single Cells: Probing Chemistry and Biology at their Fundamental Limit


Wednesday, February 10 | 8:00AM - 11:15AM
Personalized and Preventative Medicine
This session is from Personalized Medicine
Room: Van Horne C

Speaker 5 of 7
Jim Kaput, Nestlé Institute of Health Sciences, Switzerland
Developing n-of-1 Experimental Designs for Health Research


Wednesday, February 10 | 8:00AM - 11:15AM
Personalized and Preventative Medicine
This session is from Personalized Medicine
Room: Van Horne C

Speaker 6 of 7
Deena Mohamad Ameen Gendoo, University of Birmingham, UK
Short Talk: Investigating Pharmacological Drug Classification using Integrative Approaches


Wednesday, February 10 | 8:00AM - 11:15AM
Personalized and Preventative Medicine
This session is from Personalized Medicine
Room: Van Horne C

Speaker 7 of 7
Karla Claudio, University of Puerto Rico, USA
Short Talk: Native-American Contribution in Puerto Ricans is Associated with a Lower Warfarin Dose Requirement


Wednesday, February 10 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Wednesday, February 10 | 11:15AM - 1:00PM
Poster Setup
Room: Mezzanine 2


Wednesday, February 10 | 11:15AM - 5:00PM
On Own for Lunch


Wednesday, February 10 | 1:00PM - 10:00PM
Poster Viewing
Room: Mezzanine 2


Wednesday, February 10 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Wednesday, February 10 | 5:00PM - 7:00PM
Computational and Mathematical Models of Cancer Progression
Room: Van Horne A/B

Speaker 1 of 5
* Ben J. Raphael, Brown University, USA

Wednesday, February 10 | 5:00PM - 7:00PM
Computational and Mathematical Models of Cancer Progression
Room: Van Horne A/B

Speaker 2 of 5
Dana Pe'er, Memorial Sloan Kettering Cancer Center, USA
Computational Prediction of Driver Genes and Modules

Wednesday, February 10 | 5:00PM - 7:00PM
Computational and Mathematical Models of Cancer Progression
Room: Van Horne A/B

Speaker 3 of 5
Christina Curtis, Stanford University, USA
Quantifying the Evolutionary Dynamics of Tumor Growth and Progression

Wednesday, February 10 | 5:00PM - 7:00PM
Computational and Mathematical Models of Cancer Progression
Room: Van Horne A/B

Speaker 4 of 5
Doron Lipson, Foundation Medicine, Inc., USA
Interpreting Cancer Genomes for the Clinician

Wednesday, February 10 | 5:00PM - 7:00PM
Computational and Mathematical Models of Cancer Progression
Room: Van Horne A/B

Speaker 5 of 5
Margaret L. Hoang, Johns Hopkins University School of Medicine, USA
Short Talk: Accumulation of Somatic Mutations in Normal and Cancerous Tissues with Age

Wednesday, February 10 | 5:00PM - 7:00PM
Harnessing Big Data for Health
This session is from Personalized Medicine
Room: Van Horne C

Speaker 1 of 4
* Karin D. Rodland, Pacific Northwest National Laboratory, USA


Wednesday, February 10 | 5:00PM - 7:00PM
Harnessing Big Data for Health
This session is from Personalized Medicine
Room: Van Horne C

Speaker 2 of 4
Atul J. Butte, University of California, San Francisco, USA
Translating a Trillion Points of Data into Therapies, Diagnostics, and New Precision in Medicine


Wednesday, February 10 | 5:00PM - 7:00PM
Harnessing Big Data for Health
This session is from Personalized Medicine
Room: Van Horne C

Speaker 3 of 4
Michael P. Snyder, Stanford University School of Medicine, USA
Personal Omics Profiing


Wednesday, February 10 | 5:00PM - 7:00PM
Harnessing Big Data for Health
This session is from Personalized Medicine
Room: Van Horne C

Speaker 4 of 4
Kahn Rhrissorrakrai, IBM TJ Watson Research, USA
Short Talk: Watson Genomic Analytics: Literature-informed Dynamic Computational Model for Molecularly Targeted Therapies


Wednesday, February 10 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mezzanine 2
No registration fees are used to fund alcohol served at this function.

Wednesday, February 10 | 7:30PM - 10:00PM
Poster Session 2
Room: Mezzanine 2


Thursday, February 11 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Thursday, February 11 | 8:00AM - 11:00AM
The Other -Omes (Joint)
Room: Van Horne A/B

Speaker 1 of 5
Peter A. Jones, Van Andel Research Institute, USA
The Cancer Epigenome

Thursday, February 11 | 8:00AM - 11:00AM
The Other -Omes (Joint)
Room: Van Horne A/B

Speaker 2 of 5
Karin D. Rodland, Pacific Northwest National Laboratory, USA
The Proteogenomic Landscape of Ovarian Cancer: Integrating Genomics and Proteomics in the Context of Clinical Outcome

Thursday, February 11 | 8:00AM - 11:00AM
The Other -Omes (Joint)
Room: Van Horne A/B

Speaker 3 of 5
Joseph R. Ecker, The Salk Institute for Biological Studies, USA
The Personal Epigenome

Thursday, February 11 | 8:00AM - 11:00AM
The Other -Omes (Joint)
Room: Van Horne A/B

Speaker 4 of 5
Jason Wong, University of New South Wales, Australia
Short Talk: Transcription and Differential DNA Repair Underlie Promoter Mutation Hotspots in Cancer Genomes

Thursday, February 11 | 8:00AM - 11:00AM
The Other -Omes (Joint)
Room: Van Horne A/B

Speaker 5 of 5
George I. Mias, Michigan State University, USA
Short Talk: Resources For Integrative Dynamic Omics and Personalized Medicine

Thursday, February 11 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Thursday, February 11 | 11:00AM - 5:00PM
On Own for Lunch


Thursday, February 11 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Thursday, February 11 | 5:00PM - 6:45PM
Single Cell and Liquid Biopsy Genomics of Cancer
Room: Van Horne A/B

Speaker 1 of 4
* Peter A. Jones, Van Andel Research Institute, USA

Thursday, February 11 | 5:00PM - 6:45PM
Single Cell and Liquid Biopsy Genomics of Cancer
Room: Van Horne A/B

Speaker 2 of 4
Nicholas Navin, University of Texas MD Anderson Cancer Center, USA
Investigating Clonal Evolution in Breast Cancer by Single Cell DNA Sequencing

Thursday, February 11 | 5:00PM - 6:45PM
Single Cell and Liquid Biopsy Genomics of Cancer
Room: Van Horne A/B

Speaker 3 of 4
Michael Morrissey, Novartis Institutes for Biomedical Research, USA
Enabling Clinical Trials using cfDNA

Thursday, February 11 | 5:00PM - 6:45PM
Single Cell and Liquid Biopsy Genomics of Cancer
Room: Van Horne A/B

Speaker 4 of 4
Caroline Dive, Cancer Research UK Manchester Institute, UK
Circulating Tumor Cells and Circulating Free DNA Studies of Lung Adenocarcinoma

Thursday, February 11 | 5:00PM - 7:00PM
Translational and Clinical Genomics
This session is from Personalized Medicine
Room: Van Horne C

Speaker 1 of 4
Howard J. Jacob, HudsonAlpha Institute for Bioltechnology, USA
Advancing Clinical Care with Genomic Tools


Thursday, February 11 | 5:00PM - 7:00PM
Translational and Clinical Genomics
This session is from Personalized Medicine
Room: Van Horne C

Speaker 2 of 4
Diana W. Bianchi, NICHD, National Institutes of Health, USA
Noninvasive Prenatal DNA Sequencing Transforms Care and Detects Occult Malignancies


Thursday, February 11 | 5:00PM - 7:00PM
Translational and Clinical Genomics
This session is from Personalized Medicine
Room: Van Horne C

Speaker 3 of 4
Philip Awadalla, Ontario Institute for Cancer Research, University of Toronto, Canada
Exploiting Large Population Cohorts to Capture Genomic x Environmental Determinants of Chronic Diseases


Thursday, February 11 | 5:00PM - 7:00PM
Translational and Clinical Genomics
This session is from Personalized Medicine
Room: Van Horne C

Speaker 4 of 4
Gregory D. Poore, Duke University, USA
Short Talk: An Integrative Transcriptomics Model for Predicting Host Molecular Responses to Acute Respiratory Infections


Thursday, February 11 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Van Horne A/B


Thursday, February 11 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mezzanine 2
No registration fees are used to fund alcohol served at this function.

Thursday, February 11 | 8:00PM - 11:00PM
Entertainment
Room: Mezzanine 2
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, February 11 | 8:00PM - 11:00PM
Cash Bar
Room: Mezzanine 2


Friday, February 12 | 10:25AM - 10:25AM
Departure


*Session Chair.