Web Desc
Autophagy: Molecular and Physiological Mechanisms
Organizer(s): Sharon A. Tooze, Ana Maria Cuervo and Noboru Mizushima
Date: June 05 - 09, 2016
Location: Whistler Conference Centre, Whistler, BC, Canada
Sponsored by Novartis Institutes for BioMedical Research
For important information on the coronavirus, please click here
Summary of Meeting:
Autophagy, an evolutionarily conserved pathway, is required for homeostasis, growth and survival in eukaryotic cells. Deregulation of autophagy is implicated in many human diseases, and mutations in autophagy genes are known to be a direct cause of severe human disorders. There are global efforts to understand the role of autophagy in disease pathogenesis and to develop therapeutic strategies to control the autophagic response. However, the latter is hampered by the lack of biomarkers, and disease-specific, selective autophagy targets. Overcoming this barrier in development of therapeutics will require a better understanding of basic autophagy biology. This meeting will specifically address the basic molecular pathway to increase our knowledge of the genes, proteins and signaling pathways involved in autophagy. The program will assemble experts in the molecular details of the diverse autophagic pathways and therefore provide clinicians and pharmaceutical companies with information to develop new, specific targets.
Scholarship Deadline: February 4 2016
Discounted Abstract Deadline: February 4 2016
Abstract Deadline: March 8 2016
Discounted Registration Deadline: April 5 2016
Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.


Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Novartis Institutes for BioMedical Research
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

EMBO Young Investigator Programme

Novartis Institutes for BioMedical Research
We gratefully acknowledge the generous grant for this conference provided by:

National Cancer Institute (NCI)
Grant No. 1R13CA206357-01
Funding for this conference was made possible (in part) by 1R13CA206357-01 from the National Cancer Institute. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, June 05 | 4:00PM - 8:00PM
Arrival and Registration
Room: Grand Foyer


Sunday, June 05 | 6:00PM - 8:00PM
Welcome Mixer
Room: Grand Foyer
No registration fees are used to fund alcohol served at this function.

Monday, June 06 | 7:30AM - 8:30AM
Breakfast
Room: Sea to Sky C


Monday, June 06 | 8:00AM - 8:30AM
Poster Setup
Room: Grand Foyer


Monday, June 06 | 8:30AM - 5:00PM
Poster Viewing
Room: Grand Foyer


Monday, June 06 | 8:30AM - 11:45AM
Molecular Mechanisms of Autophagy I
Room: Sea to Sky B

Speaker 1 of 8
* Vojo Deretic, University of New Mexico Health Sciences Center, USA

Monday, June 06 | 8:30AM - 11:45AM
Molecular Mechanisms of Autophagy I
Room: Sea to Sky B

Speaker 2 of 8
Tamotsu Yoshimori, Osaka University, Japan
Regulation of Membrane Dynamics in Autophagy; Its Implication in Diseases

Monday, June 06 | 8:30AM - 11:45AM
Molecular Mechanisms of Autophagy I
Room: Sea to Sky B

Speaker 3 of 8
Sharon A. Tooze, Francis Crick Institute, UK
Molecular Pathways and Vesicular Traffic during Autophagosome Formation

Monday, June 06 | 8:30AM - 11:45AM
Molecular Mechanisms of Autophagy I
Room: Sea to Sky B


Coffee Break

Monday, June 06 | 8:30AM - 11:45AM
Molecular Mechanisms of Autophagy I
Room: Sea to Sky B

Speaker 5 of 8
Noboru Mizushima, University of Tokyo, Japan
The Life of the Autophagosome

Monday, June 06 | 8:30AM - 11:45AM
Molecular Mechanisms of Autophagy I
Room: Sea to Sky B

Speaker 6 of 8
Fulvio Reggiori, University Medical Centre Groningen, Netherlands
Spatial Atg8 Deconjugation Depends on the Regulation of Atg4 Function by Atg1 Phosphorylation and Phosphatidylinositol-3-Phosphate Levels

Monday, June 06 | 8:30AM - 11:45AM
Molecular Mechanisms of Autophagy I
Room: Sea to Sky B

Speaker 7 of 8
Josh Lyon Andersen, Brigham Young University, USA
Short Talk: Regulation of mAtg9A Phosphorylation by an AMPK/ULK1/LIMD1 Complex

Monday, June 06 | 8:30AM - 11:45AM
Molecular Mechanisms of Autophagy I
Room: Sea to Sky B

Speaker 8 of 8
Roarke A. Kamber, Harvard University, USA
Short Talk: Local Control of Autophagy Receptor Activation

Monday, June 06 | 11:45AM - 12:30PM
Lunch
Room: Sea to Sky C


Monday, June 06 | 12:00PM - 2:30PM
Poster Session 1
Room: Grand Foyer


Monday, June 06 | 2:30PM - 4:30PM
Workshop 1: Selective and Non-Canonical Autophagy Pathways
Room: Sea to Sky B

Speaker 1 of 6
Allyson Anding, University of Massachusetts Medical School, USA
A Novel and Conserved Ubiquitin Receptor that is Required for Parkin-Dependent Mitophagy

Monday, June 06 | 2:30PM - 4:30PM
Workshop 1: Selective and Non-Canonical Autophagy Pathways
Room: Sea to Sky B

Speaker 2 of 6
* Li-Lin Du, National Institute of Biological Sciences, China
Fission Yeast Nbr1 Acts as a Cargo Receptor in an ESCRT-Dependent Vacuolar Targeting Pathway

Monday, June 06 | 2:30PM - 4:30PM
Workshop 1: Selective and Non-Canonical Autophagy Pathways
Room: Sea to Sky B

Speaker 3 of 6
Oliver Florey, Babraham Institute, UK
Novel Mechanisms of ATG16L1 Recruitment in Non-Canonical Autophagy

Monday, June 06 | 2:30PM - 4:30PM
Workshop 1: Selective and Non-Canonical Autophagy Pathways
Room: Sea to Sky B

Speaker 4 of 6
* Katarzyna Zientara-Rytter, University of California, San Diego, USA
New Roles of Atg37 and Pex3 in Assembly of the Pexophagic Receptor Protein Complex

Monday, June 06 | 2:30PM - 4:30PM
Workshop 1: Selective and Non-Canonical Autophagy Pathways
Room: Sea to Sky B

Speaker 5 of 6
Jakob Mejlvang, UiT The Arctic University of Norway, Norway
The Immediate Autophagic Response to Starvation (IARS) is Independent of Canonical Macroautophagy but Dependent on ESCRT-III and Vps4

Monday, June 06 | 2:30PM - 4:30PM
Workshop 1: Selective and Non-Canonical Autophagy Pathways
Room: Sea to Sky B

Speaker 6 of 6
Jina Lee, Hannam University, South Korea
Development of a New Autophagosome Sensor with an LC3-Interacting Region (LIR) Motif and a Hydrophobic Domain

Monday, June 06 | 4:30PM - 5:00PM
Coffee Available
Room: Grand Foyer


Monday, June 06 | 5:00PM - 7:00PM
Molecular Mechanisms of Autophagy II
Room: Sea to Sky B
To establish the key questions in autophagy.
Speaker 1 of 5
* Sascha Martens, University of Vienna, Austria

Monday, June 06 | 5:00PM - 7:00PM
Molecular Mechanisms of Autophagy II
Room: Sea to Sky B
To establish the key questions in autophagy.
Speaker 2 of 5
Nicholas Ktistakis, Babraham Institute, UK
Starvation-Induced and Selective Autophagy: The First 3 Minutes

Monday, June 06 | 5:00PM - 7:00PM
Molecular Mechanisms of Autophagy II
Room: Sea to Sky B
To establish the key questions in autophagy.
Speaker 3 of 5
Francesco Cecconi, University of Rome Tor Vergata, Italy
AMBRA1 Negative Control at the Crossroads among Autophagy, Cell Proliferation and Cell Death


Monday, June 06 | 5:00PM - 7:00PM
Molecular Mechanisms of Autophagy II
Room: Sea to Sky B
To establish the key questions in autophagy.
Speaker 4 of 5
Claudine Kraft, University of Freiburg, Germany
EMBO Young Investigator Lecture: Molecular Regulation of Autophagy: Signaling and Beyond

Monday, June 06 | 5:00PM - 7:00PM
Molecular Mechanisms of Autophagy II
Room: Sea to Sky B
To establish the key questions in autophagy.
Speaker 5 of 5
Carsten Sachse, Forschungszentrum Jülich, Germany
Short Talk: Higher-Order Assemblies of Polymeric and Oligomeric Cargo Receptor Complexes form the Membrane Scaffold for Selective Autophagy

Monday, June 06 | 7:00PM - 7:00PM
On Own for Dinner


Tuesday, June 07 | 7:30AM - 8:30AM
Breakfast
Room: Sea to Sky C


Tuesday, June 07 | 8:30AM - 11:45AM
Autophagy and Diseases of Aging
Room: Sea to Sky B
To exchange scientific information between autophagy and aging community.
Speaker 1 of 8
* Alicia Melendez, Queens College - CUNY, USA

Tuesday, June 07 | 8:30AM - 11:45AM
Autophagy and Diseases of Aging
Room: Sea to Sky B
To exchange scientific information between autophagy and aging community.
Speaker 2 of 8
Ana Maria Cuervo, Albert Einstein College of Medicine, USA
Chaperone-mediated Autophagy in the Fight against Aging

Tuesday, June 07 | 8:30AM - 11:45AM
Autophagy and Diseases of Aging
Room: Sea to Sky B
To exchange scientific information between autophagy and aging community.
Speaker 3 of 8
David C. Rubinsztein, Cambridge Institute for Medical Research, UK
Autophagy, Neurodegeneration and Neurodevelopment

Tuesday, June 07 | 8:30AM - 11:45AM
Autophagy and Diseases of Aging
Room: Sea to Sky B
To exchange scientific information between autophagy and aging community.

Coffee Break

Tuesday, June 07 | 8:30AM - 11:45AM
Autophagy and Diseases of Aging
Room: Sea to Sky B
To exchange scientific information between autophagy and aging community.
Speaker 5 of 8
Anne Simonsen, University of Oslo, Norway
Regulation of Autophagosome Biogenesis by Lipid-Binding Proteins

Tuesday, June 07 | 8:30AM - 11:45AM
Autophagy and Diseases of Aging
Room: Sea to Sky B
To exchange scientific information between autophagy and aging community.
Speaker 6 of 8
Peter C. Butler, University of California, Los Angeles, USA
Autophagy and Diabetes

Tuesday, June 07 | 8:30AM - 11:45AM
Autophagy and Diseases of Aging
Room: Sea to Sky B
To exchange scientific information between autophagy and aging community.
Speaker 7 of 8
Jessica Chang, Sanford Burnham Prebys Medical Discovery Institute, USA
Short Talk: Spatial and Temporal Regulation of Autophagy during C. Elegans Aging

Tuesday, June 07 | 8:30AM - 11:45AM
Autophagy and Diseases of Aging
Room: Sea to Sky B
To exchange scientific information between autophagy and aging community.
Speaker 8 of 8
Patricia Boya, Centro de Investigaciones Biológicas, CSIC, Spain
Short Talk: Lysosomal Cell Death in Animal Models of Neurodegenerative Diseases

Tuesday, June 07 | 11:45AM - 1:15PM
Chewing the Fat: Panel and Discussion about Autophagy and Fu
ture Directions of the Autophagy Field
Room: Sea to Sky B
Eric Baehrecke, Ana Maria Cuervo, Vojo Deretic and Leon Murphy met to discuss their interests in autophagy. Topics included some history, current and future areas of research interests, possible controversies, and speculation about the future directions of the autophagy field. Come enjoy a short video of their discussion, and be prepared to ask them questions.
Speaker 1 of 4
* Eric H. Baehrecke, University of Massachusetts Medical School, USA

Tuesday, June 07 | 11:45AM - 1:15PM
Chewing the Fat: Panel and Discussion about Autophagy and Fu
ture Directions of the Autophagy Field
Room: Sea to Sky B
Eric Baehrecke, Ana Maria Cuervo, Vojo Deretic and Leon Murphy met to discuss their interests in autophagy. Topics included some history, current and future areas of research interests, possible controversies, and speculation about the future directions of the autophagy field. Come enjoy a short video of their discussion, and be prepared to ask them questions.
Speaker 2 of 4
* Ana Maria Cuervo, Albert Einstein College of Medicine, USA

Tuesday, June 07 | 11:45AM - 1:15PM
Chewing the Fat: Panel and Discussion about Autophagy and Fu
ture Directions of the Autophagy Field
Room: Sea to Sky B
Eric Baehrecke, Ana Maria Cuervo, Vojo Deretic and Leon Murphy met to discuss their interests in autophagy. Topics included some history, current and future areas of research interests, possible controversies, and speculation about the future directions of the autophagy field. Come enjoy a short video of their discussion, and be prepared to ask them questions.
Speaker 3 of 4
* Vojo Deretic, University of New Mexico Health Sciences Center, USA

Tuesday, June 07 | 11:45AM - 1:15PM
Chewing the Fat: Panel and Discussion about Autophagy and Fu
ture Directions of the Autophagy Field
Room: Sea to Sky B
Eric Baehrecke, Ana Maria Cuervo, Vojo Deretic and Leon Murphy met to discuss their interests in autophagy. Topics included some history, current and future areas of research interests, possible controversies, and speculation about the future directions of the autophagy field. Come enjoy a short video of their discussion, and be prepared to ask them questions.
Speaker 4 of 4
* Leon O. Murphy, Casma Therapeutics, USA

Tuesday, June 07 | 11:45AM - 5:00PM
On Own for Lunch


Tuesday, June 07 | 11:45AM - 1:00PM
Poster Setup
Room: Grand Foyer


Tuesday, June 07 | 1:15PM - 10:00PM
Poster Viewing
Room: Grand Foyer


Tuesday, June 07 | 4:30PM - 5:00PM
Coffee Available
Room: Grand Foyer


Tuesday, June 07 | 5:00PM - 7:00PM
Regulation of Autophagic Processes
Room: Sea to Sky B
To build upon session 1 and 2 data and start to explore regulation of autophagy.
Speaker 1 of 5
* Thomas Melia, Yale School of Medicine, USA

Tuesday, June 07 | 5:00PM - 7:00PM
Regulation of Autophagic Processes
Room: Sea to Sky B
To build upon session 1 and 2 data and start to explore regulation of autophagy.
Speaker 2 of 5
Hong Zhang, Chinese Academy of Sciences, China
Differential Function of the Four WIPIs in Autophagy

Tuesday, June 07 | 5:00PM - 7:00PM
Regulation of Autophagic Processes
Room: Sea to Sky B
To build upon session 1 and 2 data and start to explore regulation of autophagy.
Speaker 3 of 5
Leon O. Murphy, Casma Therapeutics, USA
Regulation of Selective Autophagy

Tuesday, June 07 | 5:00PM - 7:00PM
Regulation of Autophagic Processes
Room: Sea to Sky B
To build upon session 1 and 2 data and start to explore regulation of autophagy.
Speaker 4 of 5
Zvulun Elazar, Weizmann Institute of Science, Israel
Role of Lipids in Autophagy

Tuesday, June 07 | 5:00PM - 7:00PM
Regulation of Autophagic Processes
Room: Sea to Sky B
To build upon session 1 and 2 data and start to explore regulation of autophagy.
Speaker 5 of 5
Hemmo Meyer, University Duisburg-Essen, Germany
Short Talk: A Role of the Ubiquitin-directed VCP/p97 AAA-ATPase in Autophagy

Tuesday, June 07 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Sea to Sky C
No registration fees are used to fund alcohol served at this function.

Tuesday, June 07 | 7:30PM - 10:00PM
Poster Session 2
Room: Grand Foyer


Wednesday, June 08 | 7:30AM - 8:30AM
Breakfast
Room: Sea to Sky C


Wednesday, June 08 | 8:30AM - 11:45AM
Molecular Reconstitution of Autophagy Machinery
Room: Sea to Sky B
Structural and reconstitution of autophagic proteins.
Speaker 1 of 8
* Zvulun Elazar, Weizmann Institute of Science, Israel

Wednesday, June 08 | 8:30AM - 11:45AM
Molecular Reconstitution of Autophagy Machinery
Room: Sea to Sky B
Structural and reconstitution of autophagic proteins.
Speaker 2 of 8
Thomas Melia, Yale School of Medicine, USA
Membrane Recognition by the Atg4 Family of Proteases

Wednesday, June 08 | 8:30AM - 11:45AM
Molecular Reconstitution of Autophagy Machinery
Room: Sea to Sky B
Structural and reconstitution of autophagic proteins.
Speaker 3 of 8
Sascha Martens, University of Vienna, Austria
EMBO Young Investigator Lecture: Molecular Mechanisms of Selective Autophagy

Wednesday, June 08 | 8:30AM - 11:45AM
Molecular Reconstitution of Autophagy Machinery
Room: Sea to Sky B
Structural and reconstitution of autophagic proteins.

Coffee Break

Wednesday, June 08 | 8:30AM - 11:45AM
Molecular Reconstitution of Autophagy Machinery
Room: Sea to Sky B
Structural and reconstitution of autophagic proteins.
Speaker 5 of 8
Thomas Wollert, Institut Pasteur Paris, France
EMBO Young Investigator Lecture: How to Make an Autophagosome – Membrane Remodeling in Autophagy

Wednesday, June 08 | 8:30AM - 11:45AM
Molecular Reconstitution of Autophagy Machinery
Room: Sea to Sky B
Structural and reconstitution of autophagic proteins.
Speaker 6 of 8
Ivan Dikic, Goethe University Medical School, Germany
Ubiquitin Regulation of Selective Autophagy

Wednesday, June 08 | 8:30AM - 11:45AM
Molecular Reconstitution of Autophagy Machinery
Room: Sea to Sky B
Structural and reconstitution of autophagic proteins.
Speaker 7 of 8
Lindsey Young, University of California, San Diego, USA
Short Talk: Structural Insights into Autophagy Initiation by PI3K Complex I

Wednesday, June 08 | 8:30AM - 11:45AM
Molecular Reconstitution of Autophagy Machinery
Room: Sea to Sky B
Structural and reconstitution of autophagic proteins.
Speaker 8 of 8
Mary Lilly, NICHD, National Institutes of Health, USA
Short Talk: The GATOR2 Complex Regulates Lysosome Acidification and Autophagic Flux Independent of TORC1 Activity

Wednesday, June 08 | 11:45AM - 5:00PM
On Own for Lunch


Wednesday, June 08 | 11:45AM - 1:00PM
Poster Setup
Room: Grand Foyer


Wednesday, June 08 | 1:00PM - 10:00PM
Poster Viewing
Room: Grand Foyer


Wednesday, June 08 | 4:30PM - 5:00PM
Coffee Available
Room: Grand Foyer


Wednesday, June 08 | 5:00PM - 7:00PM
Autophagy in Conserved Homeostatic Pathways
Room: Sea to Sky B

Speaker 1 of 5
* Claudine Kraft, University of Freiburg, Germany

Wednesday, June 08 | 5:00PM - 7:00PM
Autophagy in Conserved Homeostatic Pathways
Room: Sea to Sky B

Speaker 2 of 5
Gabor Juhasz, Biological Research Center, HAS, Hungary
Autophagosome and Endosome Maturation in Drosophila

Wednesday, June 08 | 5:00PM - 7:00PM
Autophagy in Conserved Homeostatic Pathways
Room: Sea to Sky B

Speaker 3 of 5
Masaaki Komatsu, Juntendo University School of Medicine, Japan
Autophagy-Adaptors Regulate Cellular Metabolism through Multiple Transcription-Factor Pathways

Wednesday, June 08 | 5:00PM - 7:00PM
Autophagy in Conserved Homeostatic Pathways
Room: Sea to Sky B

Speaker 4 of 5
Alicia Melendez, Queens College - CUNY, USA
Autophagy in C. elegans Development and Aging

Wednesday, June 08 | 5:00PM - 7:00PM
Autophagy in Conserved Homeostatic Pathways
Room: Sea to Sky B

Speaker 5 of 5
Tamiza Nanji, University of British Columbia, Canada
Short Talk: Molecular Organization and Interactions of the Fission Yeast Atg1 Complex

Wednesday, June 08 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Sea to Sky C
No registration fees are used to fund alcohol served at this function.

Wednesday, June 08 | 7:30PM - 10:00PM
Poster Session 3
Room: Grand Foyer


Thursday, June 09 | 7:30AM - 8:30AM
Breakfast
Room: Sea to Sky C


Thursday, June 09 | 8:30AM - 11:45AM
Autophagy in Human Pathophysiology
Room: Sea to Sky B
To explore the role of autophagy in infection and immunity, and other physiological situations.
Speaker 1 of 8
* Anne Simonsen, University of Oslo, Norway

Thursday, June 09 | 8:30AM - 11:45AM
Autophagy in Human Pathophysiology
Room: Sea to Sky B
To explore the role of autophagy in infection and immunity, and other physiological situations.
Speaker 2 of 8
Janice Lee, Foghorn Therapeutics, USA
Targeting Autophagy for Cancer Therapy

Thursday, June 09 | 8:30AM - 11:45AM
Autophagy in Human Pathophysiology
Room: Sea to Sky B
To explore the role of autophagy in infection and immunity, and other physiological situations.
Speaker 3 of 8
Vojo Deretic, University of New Mexico Health Sciences Center, USA
Talk and Crosstalk between Immune Response and Autophagy

Thursday, June 09 | 8:30AM - 11:45AM
Autophagy in Human Pathophysiology
Room: Sea to Sky B
To explore the role of autophagy in infection and immunity, and other physiological situations.

Coffee Break

Thursday, June 09 | 8:30AM - 11:45AM
Autophagy in Human Pathophysiology
Room: Sea to Sky B
To explore the role of autophagy in infection and immunity, and other physiological situations.
Speaker 5 of 8
Katja Simon, University of Oxford, UK
Autophagy Determines Hematological Cell Fate


Thursday, June 09 | 8:30AM - 11:45AM
Autophagy in Human Pathophysiology
Room: Sea to Sky B
To explore the role of autophagy in infection and immunity, and other physiological situations.
Speaker 6 of 8
Herbert (Skip) W. Virgin, Vir Biotechnology, USA
Regulation of Inflammation and Immunity by Autophagy Genes

Thursday, June 09 | 8:30AM - 11:45AM
Autophagy in Human Pathophysiology
Room: Sea to Sky B
To explore the role of autophagy in infection and immunity, and other physiological situations.
Speaker 7 of 8
Véronik Lachance, Icahn School of Medicine at Mount Sinai, USA
Short Talk: Mutation of Vps11 Causes a New Class of Leukoencephalopathy and Autophagy Impairment

Thursday, June 09 | 8:30AM - 11:45AM
Autophagy in Human Pathophysiology
Room: Sea to Sky B
To explore the role of autophagy in infection and immunity, and other physiological situations.
Speaker 8 of 8
Rhea M. Sumpter, Jr., University of Texas Southwestern Medical Center, USA
Short Talk: Fanconi Anemia Tumor Suppressor Genes Function in Selective Autophagy, Immunity and Mitochondrial Homeostasis

Thursday, June 09 | 11:45AM - 2:30PM
On Own for Lunch


Thursday, June 09 | 2:30PM - 4:30PM
Workshop 2: Challenges in Measuring and Manipulating Autopha
gy in Humans
Room: Sea to Sky B

Speaker 1 of 8
* Janice Lee, Foghorn Therapeutics, USA

Thursday, June 09 | 2:30PM - 4:30PM
Workshop 2: Challenges in Measuring and Manipulating Autopha
gy in Humans
Room: Sea to Sky B

Speaker 2 of 8
* Peter C. Butler, University of California, Los Angeles, USA

Thursday, June 09 | 2:30PM - 4:30PM
Workshop 2: Challenges in Measuring and Manipulating Autopha
gy in Humans
Room: Sea to Sky B

Speaker 3 of 8
Joo Yun Jun, NICHD, National Institutes of Health, USA
Melanocortin 3 Receptor (MC3R), A Novel Regulator of Hepatic Autophagy in Obesity

Thursday, June 09 | 2:30PM - 4:30PM
Workshop 2: Challenges in Measuring and Manipulating Autopha
gy in Humans
Room: Sea to Sky B

Speaker 4 of 8
Anatoliy I. Masyuk, Mayo Clinic, USA
Dysregulated Autophagy in Cholangiocytes Contributes to the Progression of Polycystic Liver Disease

Thursday, June 09 | 2:30PM - 4:30PM
Workshop 2: Challenges in Measuring and Manipulating Autopha
gy in Humans
Room: Sea to Sky B

Speaker 5 of 8
Natalia Rodriguez Muela, Harvard University, USA
Role of Autophagy in Spinal Muscular Atrophy

Thursday, June 09 | 2:30PM - 4:30PM
Workshop 2: Challenges in Measuring and Manipulating Autopha
gy in Humans
Room: Sea to Sky B

Speaker 6 of 8
Katrin Panzitt, Medical University Graz, Austria
The Autophagy Inhibitor Rubicon is a Direct Target of the Bile Acid Receptor FXR in Human Liver and is Induced in Human Cholestasis

Thursday, June 09 | 2:30PM - 4:30PM
Workshop 2: Challenges in Measuring and Manipulating Autopha
gy in Humans
Room: Sea to Sky B

Speaker 7 of 8
Christos E. Zois, University of Oxford, UK
Targeting VPS34 to Enhance Anticancer Therapy

Thursday, June 09 | 2:30PM - 4:30PM
Workshop 2: Challenges in Measuring and Manipulating Autopha
gy in Humans
Room: Sea to Sky B

Speaker 8 of 8
Shankar J. Chinta, Touro University California, USA
High Potency Miscible Activators of TFEB and Clearance of Toxic Alpha-Synuclein Oligomers; Implications for Parkinson’s Disease

Thursday, June 09 | 4:30PM - 5:00PM
Coffee Available
Room: Grand Foyer


Thursday, June 09 | 5:00PM - 7:00PM
Autophagy and Cancer
Room: Sea to Sky B
To connect the molecular aspects to human disease.
Speaker 1 of 5
* Ana Maria Cuervo, Albert Einstein College of Medicine, USA

Thursday, June 09 | 5:00PM - 7:00PM
Autophagy and Cancer
Room: Sea to Sky B
To connect the molecular aspects to human disease.
Speaker 2 of 5
Alec Kimmelman, New York University Langone Medical Center, USA
Autophagy, Metabolism and Cancer

Thursday, June 09 | 5:00PM - 7:00PM
Autophagy and Cancer
Room: Sea to Sky B
To connect the molecular aspects to human disease.
Speaker 3 of 5
Andrew M. Thorburn, University of Colorado AMC, USA
Autophagy and Cancer Therapy

Thursday, June 09 | 5:00PM - 7:00PM
Autophagy and Cancer
Room: Sea to Sky B
To connect the molecular aspects to human disease.
Speaker 4 of 5
Kevin M. Ryan, Beatson Institute for Cancer Research, UK
Mechanism of Autophagy in Cell Death and Cancer

Thursday, June 09 | 5:00PM - 7:00PM
Autophagy and Cancer
Room: Sea to Sky B
To connect the molecular aspects to human disease.
Speaker 5 of 5
Sharon Gorski, BC Cancer Research Centre, Canada
Short Talk: Evaluation of ATG4B Expression and Function in Breast Cancer Subtypes

Thursday, June 09 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Sea to Sky B


Thursday, June 09 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Sea to Sky C
No registration fees are used to fund alcohol served at this function.

Thursday, June 09 | 8:00PM - 11:00PM
Entertainment
Room: Sea to Sky C
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, June 09 | 8:00PM - 11:00PM
Cash Bar
Room: Sea to Sky C


Friday, June 10 | 10:23AM - 10:23AM
Departure


*Session Chair
†Invited, not yet responded.