Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Autophagy: From Model Systems to Therapeutic Opportunities (2019B2)
Selective Autophagy (2018Z2)
Autophagy Network Integration in Health and Disease (2017B2)

Web Desc
Autophagy: Molecular and Physiological Mechanisms Organizer(s): Sharon A. Tooze, Ana Maria Cuervo and Noboru Mizushima Date: June 05 - 09, 2016 Location: Whistler Conference Centre, Whistler, BC, Canada Sponsored by Novartis Institutes for BioMedical Research For important information on the coronavirus, please click here Summary of Meeting: Autophagy, an evolutionarily conserved pathway, is required for homeostasis, growth and survival in eukaryotic cells. Deregulation of autophagy is implicated in many human diseases, and mutations in autophagy genes are known to be a direct cause of severe human disorders. There are global efforts to understand the role of autophagy in disease pathogenesis and to develop therapeutic strategies to control the autophagic response. However, the latter is hampered by the lack of biomarkers, and disease-specific, selective autophagy targets. Overcoming this barrier in development of therapeutics will require a better understanding of basic autophagy biology. This meeting will specifically address the basic molecular pathway to increase our knowledge of the genes, proteins and signaling pathways involved in autophagy. The program will assemble experts in the molecular details of the diverse autophagic pathways and therefore provide clinicians and pharmaceutical companies with information to develop new, specific targets. Scholarship Deadline: February 4 2016 Discounted Abstract Deadline: February 4 2016 Abstract Deadline: March 8 2016 Discounted Registration Deadline: April 5 2016 Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested. Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: EMBO Young Investigator Programme Novartis Institutes for BioMedical Research We gratefully acknowledge the generous grant for this conference provided by: National Cancer Institute (NCI) Grant No. 1R13CA206357-01 Funding for this conference was made possible (in part) by 1R13CA206357-01 from the National Cancer Institute. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Autophagy: Molecular and Physiological Mechanisms

Organizer(s): Sharon A. Tooze, Ana Maria Cuervo and Noboru Mizushima

Date: June 05 - 09, 2016
Location: Whistler Conference Centre, Whistler, BC, Canada

Sponsored by Novartis Institutes for BioMedical Research

For important information on the coronavirus, please click here

Summary of Meeting:

Autophagy, an evolutionarily conserved pathway, is required for homeostasis, growth and survival in eukaryotic cells. Deregulation of autophagy is implicated in many human diseases, and mutations in autophagy genes are known to be a direct cause of severe human disorders. There are global efforts to understand the role of autophagy in disease pathogenesis and to develop therapeutic strategies to control the autophagic response. However, the latter is hampered by the lack of biomarkers, and disease-specific, selective autophagy targets. Overcoming this barrier in development of therapeutics will require a better understanding of basic autophagy biology. This meeting will specifically address the basic molecular pathway to increase our knowledge of the genes, proteins and signaling pathways involved in autophagy. The program will assemble experts in the molecular details of the diverse autophagic pathways and therefore provide clinicians and pharmaceutical companies with information to develop new, specific targets.

Scholarship Deadline: February 4 2016

Discounted Abstract Deadline: February 4 2016

Abstract Deadline: March 8 2016

Discounted Registration Deadline: April 5 2016

Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

EMBO Young Investigator Programme

Novartis Institutes for BioMedical Research

We gratefully acknowledge the generous grant for this conference provided by:

National Cancer Institute (NCI)
Grant No. 1R13CA206357-01
Funding for this conference was made possible (in part) by 1R13CA206357-01 from the National Cancer Institute. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, June 05 \| 4:00PM - 8:00PM Arrival and Registration Room: Grand Foyer
Sunday, June 05 \| 6:00PM - 8:00PM Welcome Mixer Room: Grand Foyer No registration fees are used to fund alcohol served at this function.
Monday, June 06 \| 7:30AM - 8:30AM Breakfast Room: Sea to Sky C
Monday, June 06 \| 8:00AM - 8:30AM Poster Setup Room: Grand Foyer
Monday, June 06 \| 8:30AM - 5:00PM Poster Viewing Room: Grand Foyer
Monday, June 06 \| 8:30AM - 11:45AM Molecular Mechanisms of Autophagy I Room: Sea to Sky B Speaker 1 of 8 * Vojo Deretic, University of New Mexico Health Sciences Center, USA
Monday, June 06 \| 8:30AM - 11:45AM Molecular Mechanisms of Autophagy I Room: Sea to Sky B Speaker 2 of 8 Tamotsu Yoshimori, Osaka University, Japan Regulation of Membrane Dynamics in Autophagy; Its Implication in Diseases
Monday, June 06 \| 8:30AM - 11:45AM Molecular Mechanisms of Autophagy I Room: Sea to Sky B Speaker 3 of 8 Sharon A. Tooze, Francis Crick Institute, UK Molecular Pathways and Vesicular Traffic during Autophagosome Formation
Monday, June 06 \| 8:30AM - 11:45AM Molecular Mechanisms of Autophagy I Room: Sea to Sky B Coffee Break
Monday, June 06 \| 8:30AM - 11:45AM Molecular Mechanisms of Autophagy I Room: Sea to Sky B Speaker 5 of 8 Noboru Mizushima, University of Tokyo, Japan The Life of the Autophagosome
Monday, June 06 \| 8:30AM - 11:45AM Molecular Mechanisms of Autophagy I Room: Sea to Sky B Speaker 6 of 8 Fulvio Reggiori, University Medical Centre Groningen, Netherlands Spatial Atg8 Deconjugation Depends on the Regulation of Atg4 Function by Atg1 Phosphorylation and Phosphatidylinositol-3-Phosphate Levels
Monday, June 06 \| 8:30AM - 11:45AM Molecular Mechanisms of Autophagy I Room: Sea to Sky B Speaker 7 of 8 Josh Lyon Andersen, Brigham Young University, USA Short Talk: Regulation of mAtg9A Phosphorylation by an AMPK/ULK1/LIMD1 Complex
Monday, June 06 \| 8:30AM - 11:45AM Molecular Mechanisms of Autophagy I Room: Sea to Sky B Speaker 8 of 8 Roarke A. Kamber, Harvard University, USA Short Talk: Local Control of Autophagy Receptor Activation
Monday, June 06 \| 11:45AM - 12:30PM Lunch Room: Sea to Sky C
Monday, June 06 \| 12:00PM - 2:30PM Poster Session 1 Room: Grand Foyer
Monday, June 06 \| 2:30PM - 4:30PM Workshop 1: Selective and Non-Canonical Autophagy Pathways Room: Sea to Sky B Speaker 1 of 6 Allyson Anding, University of Massachusetts Medical School, USA A Novel and Conserved Ubiquitin Receptor that is Required for Parkin-Dependent Mitophagy
Monday, June 06 \| 2:30PM - 4:30PM Workshop 1: Selective and Non-Canonical Autophagy Pathways Room: Sea to Sky B Speaker 2 of 6 * Li-Lin Du, National Institute of Biological Sciences, China Fission Yeast Nbr1 Acts as a Cargo Receptor in an ESCRT-Dependent Vacuolar Targeting Pathway
Monday, June 06 \| 2:30PM - 4:30PM Workshop 1: Selective and Non-Canonical Autophagy Pathways Room: Sea to Sky B Speaker 3 of 6 Oliver Florey, Babraham Institute, UK Novel Mechanisms of ATG16L1 Recruitment in Non-Canonical Autophagy
Monday, June 06 \| 2:30PM - 4:30PM Workshop 1: Selective and Non-Canonical Autophagy Pathways Room: Sea to Sky B Speaker 4 of 6 * Katarzyna Zientara-Rytter, University of California, San Diego, USA New Roles of Atg37 and Pex3 in Assembly of the Pexophagic Receptor Protein Complex
Monday, June 06 \| 2:30PM - 4:30PM Workshop 1: Selective and Non-Canonical Autophagy Pathways Room: Sea to Sky B Speaker 5 of 6 Jakob Mejlvang, UiT The Arctic University of Norway, Norway The Immediate Autophagic Response to Starvation (IARS) is Independent of Canonical Macroautophagy but Dependent on ESCRT-III and Vps4
Monday, June 06 \| 2:30PM - 4:30PM Workshop 1: Selective and Non-Canonical Autophagy Pathways Room: Sea to Sky B Speaker 6 of 6 Jina Lee, Hannam University, South Korea Development of a New Autophagosome Sensor with an LC3-Interacting Region (LIR) Motif and a Hydrophobic Domain
Monday, June 06 \| 4:30PM - 5:00PM Coffee Available Room: Grand Foyer
Monday, June 06 \| 5:00PM - 7:00PM Molecular Mechanisms of Autophagy II Room: Sea to Sky B To establish the key questions in autophagy. Speaker 1 of 5 * Sascha Martens, University of Vienna, Austria
Monday, June 06 \| 5:00PM - 7:00PM Molecular Mechanisms of Autophagy II Room: Sea to Sky B To establish the key questions in autophagy. Speaker 2 of 5 Nicholas Ktistakis, Babraham Institute, UK Starvation-Induced and Selective Autophagy: The First 3 Minutes
Monday, June 06 \| 5:00PM - 7:00PM Molecular Mechanisms of Autophagy II Room: Sea to Sky B To establish the key questions in autophagy. Speaker 3 of 5 Francesco Cecconi, University of Rome Tor Vergata, Italy AMBRA1 Negative Control at the Crossroads among Autophagy, Cell Proliferation and Cell Death
Monday, June 06 \| 5:00PM - 7:00PM Molecular Mechanisms of Autophagy II Room: Sea to Sky B To establish the key questions in autophagy. Speaker 4 of 5 Claudine Kraft, University of Freiburg, Germany EMBO Young Investigator Lecture: Molecular Regulation of Autophagy: Signaling and Beyond
Monday, June 06 \| 5:00PM - 7:00PM Molecular Mechanisms of Autophagy II Room: Sea to Sky B To establish the key questions in autophagy. Speaker 5 of 5 Carsten Sachse, Forschungszentrum Jülich, Germany Short Talk: Higher-Order Assemblies of Polymeric and Oligomeric Cargo Receptor Complexes form the Membrane Scaffold for Selective Autophagy
Monday, June 06 \| 7:00PM - 7:00PM On Own for Dinner
Tuesday, June 07 \| 7:30AM - 8:30AM Breakfast Room: Sea to Sky C
Tuesday, June 07 \| 8:30AM - 11:45AM Autophagy and Diseases of Aging Room: Sea to Sky B To exchange scientific information between autophagy and aging community. Speaker 1 of 8 * Alicia Melendez, Queens College - CUNY, USA
Tuesday, June 07 \| 8:30AM - 11:45AM Autophagy and Diseases of Aging Room: Sea to Sky B To exchange scientific information between autophagy and aging community. Speaker 2 of 8 Ana Maria Cuervo, Albert Einstein College of Medicine, USA Chaperone-mediated Autophagy in the Fight against Aging
Tuesday, June 07 \| 8:30AM - 11:45AM Autophagy and Diseases of Aging Room: Sea to Sky B To exchange scientific information between autophagy and aging community. Speaker 3 of 8 David C. Rubinsztein, Cambridge Institute for Medical Research, UK Autophagy, Neurodegeneration and Neurodevelopment
Tuesday, June 07 \| 8:30AM - 11:45AM Autophagy and Diseases of Aging Room: Sea to Sky B To exchange scientific information between autophagy and aging community. Coffee Break
Tuesday, June 07 \| 8:30AM - 11:45AM Autophagy and Diseases of Aging Room: Sea to Sky B To exchange scientific information between autophagy and aging community. Speaker 5 of 8 Anne Simonsen, University of Oslo, Norway Regulation of Autophagosome Biogenesis by Lipid-Binding Proteins
Tuesday, June 07 \| 8:30AM - 11:45AM Autophagy and Diseases of Aging Room: Sea to Sky B To exchange scientific information between autophagy and aging community. Speaker 6 of 8 Peter C. Butler, University of California, Los Angeles, USA Autophagy and Diabetes
Tuesday, June 07 \| 8:30AM - 11:45AM Autophagy and Diseases of Aging Room: Sea to Sky B To exchange scientific information between autophagy and aging community. Speaker 7 of 8 Jessica Chang, Sanford Burnham Prebys Medical Discovery Institute, USA Short Talk: Spatial and Temporal Regulation of Autophagy during C. Elegans Aging
Tuesday, June 07 \| 8:30AM - 11:45AM Autophagy and Diseases of Aging Room: Sea to Sky B To exchange scientific information between autophagy and aging community. Speaker 8 of 8 Patricia Boya, Centro de Investigaciones Biológicas, CSIC, Spain Short Talk: Lysosomal Cell Death in Animal Models of Neurodegenerative Diseases
Tuesday, June 07 \| 11:45AM - 1:15PM Chewing the Fat: Panel and Discussion about Autophagy and Fu ture Directions of the Autophagy Field Room: Sea to Sky B Eric Baehrecke, Ana Maria Cuervo, Vojo Deretic and Leon Murphy met to discuss their interests in autophagy. Topics included some history, current and future areas of research interests, possible controversies, and speculation about the future directions of the autophagy field. Come enjoy a short video of their discussion, and be prepared to ask them questions. Speaker 1 of 4 * Eric H. Baehrecke, University of Massachusetts Medical School, USA
Tuesday, June 07 \| 11:45AM - 1:15PM Chewing the Fat: Panel and Discussion about Autophagy and Fu ture Directions of the Autophagy Field Room: Sea to Sky B Eric Baehrecke, Ana Maria Cuervo, Vojo Deretic and Leon Murphy met to discuss their interests in autophagy. Topics included some history, current and future areas of research interests, possible controversies, and speculation about the future directions of the autophagy field. Come enjoy a short video of their discussion, and be prepared to ask them questions. Speaker 2 of 4 * Ana Maria Cuervo, Albert Einstein College of Medicine, USA
Tuesday, June 07 \| 11:45AM - 1:15PM Chewing the Fat: Panel and Discussion about Autophagy and Fu ture Directions of the Autophagy Field Room: Sea to Sky B Eric Baehrecke, Ana Maria Cuervo, Vojo Deretic and Leon Murphy met to discuss their interests in autophagy. Topics included some history, current and future areas of research interests, possible controversies, and speculation about the future directions of the autophagy field. Come enjoy a short video of their discussion, and be prepared to ask them questions. Speaker 3 of 4 * Vojo Deretic, University of New Mexico Health Sciences Center, USA
Tuesday, June 07 \| 11:45AM - 1:15PM Chewing the Fat: Panel and Discussion about Autophagy and Fu ture Directions of the Autophagy Field Room: Sea to Sky B Eric Baehrecke, Ana Maria Cuervo, Vojo Deretic and Leon Murphy met to discuss their interests in autophagy. Topics included some history, current and future areas of research interests, possible controversies, and speculation about the future directions of the autophagy field. Come enjoy a short video of their discussion, and be prepared to ask them questions. Speaker 4 of 4 * Leon O. Murphy, Casma Therapeutics, USA
Tuesday, June 07 \| 11:45AM - 5:00PM On Own for Lunch
Tuesday, June 07 \| 11:45AM - 1:00PM Poster Setup Room: Grand Foyer
Tuesday, June 07 \| 1:15PM - 10:00PM Poster Viewing Room: Grand Foyer
Tuesday, June 07 \| 4:30PM - 5:00PM Coffee Available Room: Grand Foyer
Tuesday, June 07 \| 5:00PM - 7:00PM Regulation of Autophagic Processes Room: Sea to Sky B To build upon session 1 and 2 data and start to explore regulation of autophagy. Speaker 1 of 5 * Thomas Melia, Yale School of Medicine, USA
Tuesday, June 07 \| 5:00PM - 7:00PM Regulation of Autophagic Processes Room: Sea to Sky B To build upon session 1 and 2 data and start to explore regulation of autophagy. Speaker 2 of 5 Hong Zhang, Chinese Academy of Sciences, China Differential Function of the Four WIPIs in Autophagy
Tuesday, June 07 \| 5:00PM - 7:00PM Regulation of Autophagic Processes Room: Sea to Sky B To build upon session 1 and 2 data and start to explore regulation of autophagy. Speaker 3 of 5 Leon O. Murphy, Casma Therapeutics, USA Regulation of Selective Autophagy
Tuesday, June 07 \| 5:00PM - 7:00PM Regulation of Autophagic Processes Room: Sea to Sky B To build upon session 1 and 2 data and start to explore regulation of autophagy. Speaker 4 of 5 Zvulun Elazar, Weizmann Institute of Science, Israel Role of Lipids in Autophagy
Tuesday, June 07 \| 5:00PM - 7:00PM Regulation of Autophagic Processes Room: Sea to Sky B To build upon session 1 and 2 data and start to explore regulation of autophagy. Speaker 5 of 5 Hemmo Meyer, University Duisburg-Essen, Germany Short Talk: A Role of the Ubiquitin-directed VCP/p97 AAA-ATPase in Autophagy
Tuesday, June 07 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sea to Sky C No registration fees are used to fund alcohol served at this function.
Tuesday, June 07 \| 7:30PM - 10:00PM Poster Session 2 Room: Grand Foyer
Wednesday, June 08 \| 7:30AM - 8:30AM Breakfast Room: Sea to Sky C
Wednesday, June 08 \| 8:30AM - 11:45AM Molecular Reconstitution of Autophagy Machinery Room: Sea to Sky B Structural and reconstitution of autophagic proteins. Speaker 1 of 8 * Zvulun Elazar, Weizmann Institute of Science, Israel
Wednesday, June 08 \| 8:30AM - 11:45AM Molecular Reconstitution of Autophagy Machinery Room: Sea to Sky B Structural and reconstitution of autophagic proteins. Speaker 2 of 8 Thomas Melia, Yale School of Medicine, USA Membrane Recognition by the Atg4 Family of Proteases
Wednesday, June 08 \| 8:30AM - 11:45AM Molecular Reconstitution of Autophagy Machinery Room: Sea to Sky B Structural and reconstitution of autophagic proteins. Speaker 3 of 8 Sascha Martens, University of Vienna, Austria EMBO Young Investigator Lecture: Molecular Mechanisms of Selective Autophagy
Wednesday, June 08 \| 8:30AM - 11:45AM Molecular Reconstitution of Autophagy Machinery Room: Sea to Sky B Structural and reconstitution of autophagic proteins. Coffee Break
Wednesday, June 08 \| 8:30AM - 11:45AM Molecular Reconstitution of Autophagy Machinery Room: Sea to Sky B Structural and reconstitution of autophagic proteins. Speaker 5 of 8 Thomas Wollert, Institut Pasteur Paris, France EMBO Young Investigator Lecture: How to Make an Autophagosome – Membrane Remodeling in Autophagy
Wednesday, June 08 \| 8:30AM - 11:45AM Molecular Reconstitution of Autophagy Machinery Room: Sea to Sky B Structural and reconstitution of autophagic proteins. Speaker 6 of 8 Ivan Dikic, Goethe University Medical School, Germany Ubiquitin Regulation of Selective Autophagy
Wednesday, June 08 \| 8:30AM - 11:45AM Molecular Reconstitution of Autophagy Machinery Room: Sea to Sky B Structural and reconstitution of autophagic proteins. Speaker 7 of 8 Lindsey Young, University of California, San Diego, USA Short Talk: Structural Insights into Autophagy Initiation by PI3K Complex I
Wednesday, June 08 \| 8:30AM - 11:45AM Molecular Reconstitution of Autophagy Machinery Room: Sea to Sky B Structural and reconstitution of autophagic proteins. Speaker 8 of 8 Mary Lilly, NICHD, National Institutes of Health, USA Short Talk: The GATOR2 Complex Regulates Lysosome Acidification and Autophagic Flux Independent of TORC1 Activity
Wednesday, June 08 \| 11:45AM - 5:00PM On Own for Lunch
Wednesday, June 08 \| 11:45AM - 1:00PM Poster Setup Room: Grand Foyer
Wednesday, June 08 \| 1:00PM - 10:00PM Poster Viewing Room: Grand Foyer
Wednesday, June 08 \| 4:30PM - 5:00PM Coffee Available Room: Grand Foyer
Wednesday, June 08 \| 5:00PM - 7:00PM Autophagy in Conserved Homeostatic Pathways Room: Sea to Sky B Speaker 1 of 5 * Claudine Kraft, University of Freiburg, Germany
Wednesday, June 08 \| 5:00PM - 7:00PM Autophagy in Conserved Homeostatic Pathways Room: Sea to Sky B Speaker 2 of 5 Gabor Juhasz, Biological Research Center, HAS, Hungary Autophagosome and Endosome Maturation in Drosophila
Wednesday, June 08 \| 5:00PM - 7:00PM Autophagy in Conserved Homeostatic Pathways Room: Sea to Sky B Speaker 3 of 5 Masaaki Komatsu, Juntendo University School of Medicine, Japan Autophagy-Adaptors Regulate Cellular Metabolism through Multiple Transcription-Factor Pathways
Wednesday, June 08 \| 5:00PM - 7:00PM Autophagy in Conserved Homeostatic Pathways Room: Sea to Sky B Speaker 4 of 5 Alicia Melendez, Queens College - CUNY, USA Autophagy in C. elegans Development and Aging
Wednesday, June 08 \| 5:00PM - 7:00PM Autophagy in Conserved Homeostatic Pathways Room: Sea to Sky B Speaker 5 of 5 Tamiza Nanji, University of British Columbia, Canada Short Talk: Molecular Organization and Interactions of the Fission Yeast Atg1 Complex
Wednesday, June 08 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sea to Sky C No registration fees are used to fund alcohol served at this function.
Wednesday, June 08 \| 7:30PM - 10:00PM Poster Session 3 Room: Grand Foyer
Thursday, June 09 \| 7:30AM - 8:30AM Breakfast Room: Sea to Sky C
Thursday, June 09 \| 8:30AM - 11:45AM Autophagy in Human Pathophysiology Room: Sea to Sky B To explore the role of autophagy in infection and immunity, and other physiological situations. Speaker 1 of 8 * Anne Simonsen, University of Oslo, Norway
Thursday, June 09 \| 8:30AM - 11:45AM Autophagy in Human Pathophysiology Room: Sea to Sky B To explore the role of autophagy in infection and immunity, and other physiological situations. Speaker 2 of 8 Janice Lee, Foghorn Therapeutics, USA Targeting Autophagy for Cancer Therapy
Thursday, June 09 \| 8:30AM - 11:45AM Autophagy in Human Pathophysiology Room: Sea to Sky B To explore the role of autophagy in infection and immunity, and other physiological situations. Speaker 3 of 8 Vojo Deretic, University of New Mexico Health Sciences Center, USA Talk and Crosstalk between Immune Response and Autophagy
Thursday, June 09 \| 8:30AM - 11:45AM Autophagy in Human Pathophysiology Room: Sea to Sky B To explore the role of autophagy in infection and immunity, and other physiological situations. Coffee Break
Thursday, June 09 \| 8:30AM - 11:45AM Autophagy in Human Pathophysiology Room: Sea to Sky B To explore the role of autophagy in infection and immunity, and other physiological situations. Speaker 5 of 8 Katja Simon, University of Oxford, UK Autophagy Determines Hematological Cell Fate
Thursday, June 09 \| 8:30AM - 11:45AM Autophagy in Human Pathophysiology Room: Sea to Sky B To explore the role of autophagy in infection and immunity, and other physiological situations. Speaker 6 of 8 Herbert (Skip) W. Virgin, Vir Biotechnology, USA Regulation of Inflammation and Immunity by Autophagy Genes
Thursday, June 09 \| 8:30AM - 11:45AM Autophagy in Human Pathophysiology Room: Sea to Sky B To explore the role of autophagy in infection and immunity, and other physiological situations. Speaker 7 of 8 Véronik Lachance, Icahn School of Medicine at Mount Sinai, USA Short Talk: Mutation of Vps11 Causes a New Class of Leukoencephalopathy and Autophagy Impairment
Thursday, June 09 \| 8:30AM - 11:45AM Autophagy in Human Pathophysiology Room: Sea to Sky B To explore the role of autophagy in infection and immunity, and other physiological situations. Speaker 8 of 8 Rhea M. Sumpter, Jr., University of Texas Southwestern Medical Center, USA Short Talk: Fanconi Anemia Tumor Suppressor Genes Function in Selective Autophagy, Immunity and Mitochondrial Homeostasis
Thursday, June 09 \| 11:45AM - 2:30PM On Own for Lunch
Thursday, June 09 \| 2:30PM - 4:30PM Workshop 2: Challenges in Measuring and Manipulating Autopha gy in Humans Room: Sea to Sky B Speaker 1 of 8 * Janice Lee, Foghorn Therapeutics, USA
Thursday, June 09 \| 2:30PM - 4:30PM Workshop 2: Challenges in Measuring and Manipulating Autopha gy in Humans Room: Sea to Sky B Speaker 2 of 8 * Peter C. Butler, University of California, Los Angeles, USA
Thursday, June 09 \| 2:30PM - 4:30PM Workshop 2: Challenges in Measuring and Manipulating Autopha gy in Humans Room: Sea to Sky B Speaker 3 of 8 Joo Yun Jun, NICHD, National Institutes of Health, USA Melanocortin 3 Receptor (MC3R), A Novel Regulator of Hepatic Autophagy in Obesity
Thursday, June 09 \| 2:30PM - 4:30PM Workshop 2: Challenges in Measuring and Manipulating Autopha gy in Humans Room: Sea to Sky B Speaker 4 of 8 Anatoliy I. Masyuk, Mayo Clinic, USA Dysregulated Autophagy in Cholangiocytes Contributes to the Progression of Polycystic Liver Disease
Thursday, June 09 \| 2:30PM - 4:30PM Workshop 2: Challenges in Measuring and Manipulating Autopha gy in Humans Room: Sea to Sky B Speaker 5 of 8 Natalia Rodriguez Muela, Harvard University, USA Role of Autophagy in Spinal Muscular Atrophy
Thursday, June 09 \| 2:30PM - 4:30PM Workshop 2: Challenges in Measuring and Manipulating Autopha gy in Humans Room: Sea to Sky B Speaker 6 of 8 Katrin Panzitt, Medical University Graz, Austria The Autophagy Inhibitor Rubicon is a Direct Target of the Bile Acid Receptor FXR in Human Liver and is Induced in Human Cholestasis
Thursday, June 09 \| 2:30PM - 4:30PM Workshop 2: Challenges in Measuring and Manipulating Autopha gy in Humans Room: Sea to Sky B Speaker 7 of 8 Christos E. Zois, University of Oxford, UK Targeting VPS34 to Enhance Anticancer Therapy
Thursday, June 09 \| 2:30PM - 4:30PM Workshop 2: Challenges in Measuring and Manipulating Autopha gy in Humans Room: Sea to Sky B Speaker 8 of 8 Shankar J. Chinta, Touro University California, USA High Potency Miscible Activators of TFEB and Clearance of Toxic Alpha-Synuclein Oligomers; Implications for Parkinson’s Disease
Thursday, June 09 \| 4:30PM - 5:00PM Coffee Available Room: Grand Foyer
Thursday, June 09 \| 5:00PM - 7:00PM Autophagy and Cancer Room: Sea to Sky B To connect the molecular aspects to human disease. Speaker 1 of 5 * Ana Maria Cuervo, Albert Einstein College of Medicine, USA
Thursday, June 09 \| 5:00PM - 7:00PM Autophagy and Cancer Room: Sea to Sky B To connect the molecular aspects to human disease. Speaker 2 of 5 Alec Kimmelman, New York University Langone Medical Center, USA Autophagy, Metabolism and Cancer
Thursday, June 09 \| 5:00PM - 7:00PM Autophagy and Cancer Room: Sea to Sky B To connect the molecular aspects to human disease. Speaker 3 of 5 Andrew M. Thorburn, University of Colorado AMC, USA Autophagy and Cancer Therapy
Thursday, June 09 \| 5:00PM - 7:00PM Autophagy and Cancer Room: Sea to Sky B To connect the molecular aspects to human disease. Speaker 4 of 5 Kevin M. Ryan, Beatson Institute for Cancer Research, UK Mechanism of Autophagy in Cell Death and Cancer
Thursday, June 09 \| 5:00PM - 7:00PM Autophagy and Cancer Room: Sea to Sky B To connect the molecular aspects to human disease. Speaker 5 of 5 Sharon Gorski, BC Cancer Research Centre, Canada Short Talk: Evaluation of ATG4B Expression and Function in Breast Cancer Subtypes
Thursday, June 09 \| 7:00PM - 7:15PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Room: Sea to Sky B
Thursday, June 09 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Sea to Sky C No registration fees are used to fund alcohol served at this function.
Thursday, June 09 \| 8:00PM - 11:00PM Entertainment Room: Sea to Sky C Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
Thursday, June 09 \| 8:00PM - 11:00PM Cash Bar Room: Sea to Sky C
Friday, June 10 \| 10:23AM - 10:23AM Departure *Session Chair †Invited, not yet responded.