Web Desc
Injury, Inflammation and Fibrosis
Organizer(s): Tatiana Kisseleva, Michael Karin and Andrew M. Tager
Date: March 26 - 30, 2017
Location: Snowbird Resort, Snowbird, UT, USA
Sponsored by Boehringer Ingelheim Pharmaceuticals, Inc., Regeneron Pharmaceuticals, Inc. and Theravance Biopharma. This activity was supported by an educational grant from Celgene Corporation.
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Summary of Meeting:
Fibrosis is a common response of many organs to chronic injury and inflammation. This leads to destruction of organ architecture with loss of function. Until recently, there have been no therapies to slow the progression of fibrosis and to maintain normal organ function. Recent advances have provided new insights into the pathogenesis of fibrosis, new drug targets, and new drugs in clinical studies. This conference will bring together basic biologists and translational and clinical researchers to discuss core mechanisms underlying inflammation and fibrosis, to compare and contrast fibrotic diseases, preclinical models, the potential for regeneration and regression of fibrosis, and potential therapies. The interaction between the host genetics, the environment and the microbiome in the pathogenesis of fibrotic diseases will be addressed. Also, non-invasive methods to assess fibrosis including advanced imaging and intermediate biomarkers will be discussed. This conference will be a unique opportunity for investigators who are focused on organ-specific diseases – i.e., medical subspecialists – to participate in cross-disciplinary, multi-organ discussions in order to gain new insights into their research.
Scholarship Deadline: November 28 2016
Discounted Abstract Deadline: November 28 2016
Abstract Deadline: January 9 2017
Discounted Registration Deadline: January 23 2017
Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.


Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Boehringer Ingelheim Pharmaceuticals, Inc.Regeneron Pharmaceuticals, Inc.Theravance BiopharmaThis activity was supported by an educational grant from Celgene Corporation
We gratefully acknowledge additional support for this conference from:
Charles River
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Intercept Pharmaceuticals, Inc.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Journal of Inflammation (published by BioMed Central Ltd)
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 1R13DK112608-01
Funding for this conference was made possible (in part) by DK 112608 -01 from NIH. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, March 26 | 4:00PM - 8:00PM
Arrival and Registration
Room: Ballroom Lobby


Sunday, March 26 | 6:00PM - 8:00PM
Welcome Mixer
Room: Ballroom Lobby
No registration fees are used to fund alcohol served at this function.

Monday, March 27 | 7:00AM - 8:00AM
Breakfast
Room: Golden Cliff/Eagles


Monday, March 27 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Ballroom 1-3

Speaker 1 of 2
* Tatiana Kisseleva, University of California, San Diego, USA

Monday, March 27 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Ballroom 1-3

Speaker 2 of 2
Michael Karin, University of California, San Diego, USA
Inflammation in NASH

Monday, March 27 | 9:00AM - 11:45AM
Predisposition to Fibrosis: Genetic and Epigenetic Contribut
ions to Fibrosis

Room: Ballroom 1-3

Speaker 1 of 8
* Michael Karin, University of California, San Diego, USA

Monday, March 27 | 9:00AM - 11:45AM
Predisposition to Fibrosis: Genetic and Epigenetic Contribut
ions to Fibrosis

Room: Ballroom 1-3

Speaker 2 of 8
David A. Schwartz, University of Colorado Denver, USA
Idiopathic Pulmonary Fibrosis: A Genetic Disease that Involves Mucociliary Dysfunction of the Peripheral Airways

Monday, March 27 | 9:00AM - 11:45AM
Predisposition to Fibrosis: Genetic and Epigenetic Contribut
ions to Fibrosis

Room: Ballroom 1-3


Coffee Break

Monday, March 27 | 9:00AM - 11:45AM
Predisposition to Fibrosis: Genetic and Epigenetic Contribut
ions to Fibrosis

Room: Ballroom 1-3

Speaker 4 of 8
Mary Armanios, Johns Hopkins University School of Medicine, USA
Mechanisms of Telomere-Mediated Pulmonary Fibrosis

Monday, March 27 | 9:00AM - 11:45AM
Predisposition to Fibrosis: Genetic and Epigenetic Contribut
ions to Fibrosis

Room: Ballroom 1-3

Speaker 5 of 8
Pura Munoz Munoz Canoves, Universitat Pompeu Fabra, Spain
Senescence of the Muscle Stem Cell Population in Injured Aged Muscles

Monday, March 27 | 9:00AM - 11:45AM
Predisposition to Fibrosis: Genetic and Epigenetic Contribut
ions to Fibrosis

Room: Ballroom 1-3

Speaker 6 of 8
Alexander R. Abbas, Genentech, Inc., USA
Short Talk: Peripheral Blood Telomere Shortening Predicts Lung Function Decline in Idiopathic Pulmonary Fibrosis

Monday, March 27 | 9:00AM - 11:45AM
Predisposition to Fibrosis: Genetic and Epigenetic Contribut
ions to Fibrosis

Room: Ballroom 1-3

Speaker 7 of 8
Ty D. Troutman, University of California, San Diego, USA
Short Talk: Natural Genetic Variation Reveals Encoded Programs Employed by Kupffer Cells During Liver Fibrosis

Monday, March 27 | 9:00AM - 11:45AM
Predisposition to Fibrosis: Genetic and Epigenetic Contribut
ions to Fibrosis

Room: Ballroom 1-3

Speaker 8 of 8
Gisli Jenkins, University of Nottingham, UK
Short Talk: A Novel Polymorphism Linked to Altered Expression of AKAP13 is Associated with Susceptibility to IPF

Monday, March 27 | 11:45AM - 5:00PM
On Own for Lunch


Monday, March 27 | 11:45AM - 1:00PM
Poster Setup
Room: Superior/Superior Lobby/Wasatch


Monday, March 27 | 1:00PM - 10:00PM
Poster Viewing
Room: Superior/Superior Lobby/Wasatch


Monday, March 27 | 4:30PM - 5:00PM
Coffee Available
Room: Ballroom Lobby


Monday, March 27 | 5:00PM - 7:00PM
Getting Fibrosis Started: Epithelial Senescence and/or Injur
y

Room: Ballroom 1-3

Speaker 1 of 5
* David A. Brenner, University of California, San Diego, USA

Monday, March 27 | 5:00PM - 7:00PM
Getting Fibrosis Started: Epithelial Senescence and/or Injur
y

Room: Ballroom 1-3

Speaker 2 of 5
Joseph V. Bonventre, Brigham and Women's Hospital, Harvard Medical School, USA
Maladaptive Proximal Tubule Repair: KIM-1 and Epithelial Cell Cycle Arrest and Senescence

Monday, March 27 | 5:00PM - 7:00PM
Getting Fibrosis Started: Epithelial Senescence and/or Injur
y

Room: Ballroom 1-3

Speaker 3 of 5
Quentin M. Anstee, Newcastle University, UK
The Genetics of Non-Alcoholic Fatty Liver Disease

Monday, March 27 | 5:00PM - 7:00PM
Getting Fibrosis Started: Epithelial Senescence and/or Injur
y

Room: Ballroom 1-3

Speaker 4 of 5
Katalin Susztak, University of Pennsylvania, USA
Integrative Analysis of Metabolic and Genetic Settings in Chronic Kidney Disease

Monday, March 27 | 5:00PM - 7:00PM
Getting Fibrosis Started: Epithelial Senescence and/or Injur
y

Room: Ballroom 1-3

Speaker 5 of 5
Christy Trussoni, Mayo Clinic, USA
Short Talk: Senescent Cholangiocytes Contribute to Macrophage Recruitment in Primary Sclerosing Cholangitis

Monday, March 27 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Superior/Superior Lobby/Wasatch
No registration fees are used to fund alcohol served at this function.

Monday, March 27 | 7:30PM - 10:00PM
Poster Session 1
Room: Superior/Superior Lobby/Wasatch


Tuesday, March 28 | 7:00AM - 8:00AM
Breakfast
Room: Golden Cliff/Eagles


Tuesday, March 28 | 8:00AM - 11:15AM
Shaping Fibrotic Responses: The Role of Inflammation in Tiss
ue Repair

Room: Ballroom 1-3

Speaker 1 of 8
* John Varga, Feinberg School of Medicine, USA

Tuesday, March 28 | 8:00AM - 11:15AM
Shaping Fibrotic Responses: The Role of Inflammation in Tiss
ue Repair

Room: Ballroom 1-3

Speaker 2 of 8
Thomas A. Wynn, Pfizer, USA
Potential Pitfalls of Anti-Fibrotic Therapy: Rebound Inflammation and Failed Regeneration

Tuesday, March 28 | 8:00AM - 11:15AM
Shaping Fibrotic Responses: The Role of Inflammation in Tiss
ue Repair

Room: Ballroom 1-3

Speaker 3 of 8
Frederic Geissmann, Memorial Sloan Kettering Cancer Center, USA
Environment Regulates Pro-Inflammatory and Pro-Fibrogenic Macrophages

Tuesday, March 28 | 8:00AM - 11:15AM
Shaping Fibrotic Responses: The Role of Inflammation in Tiss
ue Repair

Room: Ballroom 1-3


Coffee Break

Tuesday, March 28 | 8:00AM - 11:15AM
Shaping Fibrotic Responses: The Role of Inflammation in Tiss
ue Repair

Room: Ballroom 1-3

Speaker 5 of 8
Akira Shizuo, Osaka University, Japan
Critical Role of Trib1 in Differentiation of Tissue-Resident M2-Like Macrophages

Tuesday, March 28 | 8:00AM - 11:15AM
Shaping Fibrotic Responses: The Role of Inflammation in Tiss
ue Repair

Room: Ballroom 1-3

Speaker 6 of 8
Jörg H.W. Distler, University of Erlangen-Nuremberg, Germany
Targeting TGFbeta-Dependent Fibroblast Activation

Tuesday, March 28 | 8:00AM - 11:15AM
Shaping Fibrotic Responses: The Role of Inflammation in Tiss
ue Repair

Room: Ballroom 1-3

Speaker 7 of 8
Richard H. Gomer, Texas A&M University, USA
Short Talk: A Positive Feedback Loop Involving Sialidases Drives Pulmonary Fibrosis

Tuesday, March 28 | 8:00AM - 11:15AM
Shaping Fibrotic Responses: The Role of Inflammation in Tiss
ue Repair

Room: Ballroom 1-3

Speaker 8 of 8
Thomas Fabre, Pfizer, USA
Short Talk: Type III Inflammation Drives Liver Fibrosis Progression by Regulating TGF-Beta Signaling Through Activation of Mapks

Tuesday, March 28 | 11:15AM - 5:00PM
On Own for Lunch


Tuesday, March 28 | 11:15AM - 1:00PM
Poster Setup
Room: Superior/Superior Lobby/Wasatch


Tuesday, March 28 | 1:00PM - 10:00PM
Poster Viewing
Room: Superior/Superior Lobby/Wasatch


Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1
Room: Ballroom 1-3

Speaker 1 of 7
* Thomas A. Wynn, Pfizer, USA

Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1
Room: Ballroom 1-3

Speaker 2 of 7
Shaik Ohidar Rahaman, University of Maryland, USA
TRPV4 Channel Regulates Dermal Fibrosis and is Associated with Scleroderma

Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1
Room: Ballroom 1-3

Speaker 3 of 7
Sang Jun Lee, Ionis Pharmaceuticals, USA
Evaluation of Antisense Oligonucleotide against CHOP in Rodent Models with ER Stress Dysfunction

Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1
Room: Ballroom 1-3

Speaker 4 of 7
Matthew L. Meizlish, Yale University, USA
Macrophages and Fibroblasts Sense Variations in Collagen Density within 3-Dimensional Matrix Environment

Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1
Room: Ballroom 1-3

Speaker 5 of 7
Jason Seidman, University of California, San Diego, USA
Kupffer Cells Regulate Liver Inflammation and Fibrosis Through NCoR

Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1
Room: Ballroom 1-3

Speaker 6 of 7
Sneha Sitaraman, University of Cincinnati College of Medicine, USA
Expression of Disease-Associated Surfactant Protein C Mutation Increases Susceptibility to Fibrosis

Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1
Room: Ballroom 1-3

Speaker 7 of 7
Angela Zeigler, University of Virginia, USA
Predicting Drivers and Modulators of Fibroblast Phenotype During Myocardial Infarction Healing

Tuesday, March 28 | 4:30PM - 5:00PM
Coffee Available
Room: Ballroom Lobby


Tuesday, March 28 | 5:00PM - 7:00PM
Creating The Scar: Factors Regulating Systemic Responses to
Fibrosis

Room: Ballroom 1-3

Speaker 1 of 5
* Akira Shizuo, Osaka University, Japan

Tuesday, March 28 | 5:00PM - 7:00PM
Creating The Scar: Factors Regulating Systemic Responses to
Fibrosis

Room: Ballroom 1-3

Speaker 2 of 5
Natalie J. Torok, University of California, Davis, USA
NADPH Oxidases in Non-Alcoholic Steatohepatitis

Tuesday, March 28 | 5:00PM - 7:00PM
Creating The Scar: Factors Regulating Systemic Responses to
Fibrosis

Room: Ballroom 1-3

Speaker 3 of 5
Erwin F. Wagner, Spanish National Cancer Research Centre, Spain
Fra-2/AP-1 Mediates Fibroblast Activation and Fibrosis Development

Tuesday, March 28 | 5:00PM - 7:00PM
Creating The Scar: Factors Regulating Systemic Responses to
Fibrosis

Room: Ballroom 1-3

Speaker 4 of 5
Rob Knight, University of California, San Diego, USA
Spatial Mapping of the Human Microbiome

Tuesday, March 28 | 5:00PM - 7:00PM
Creating The Scar: Factors Regulating Systemic Responses to
Fibrosis

Room: Ballroom 1-3

Speaker 5 of 5
Edward Marsh, Yale University, USA
Short Talk: Spatiotemporal Organization of Fibroblast-Fibroblast Networks in Homeostasis

Tuesday, March 28 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Superior/Superior Lobby/Wasatch
No registration fees are used to fund alcohol served at this function.

Tuesday, March 28 | 7:30PM - 10:00PM
Poster Session 2
Room: Superior/Superior Lobby/Wasatch


Wednesday, March 29 | 7:00AM - 8:00AM
Breakfast
Room: Golden Cliff/Eagles


Wednesday, March 29 | 8:00AM - 11:15AM
Amplifying Fibrosis: Activation of Fibrogenic Myofibroblasts
Room: Ballroom 1-3

Speaker 1 of 8
* Natalie J. Torok, University of California, Davis, USA

Wednesday, March 29 | 8:00AM - 11:15AM
Amplifying Fibrosis: Activation of Fibrogenic Myofibroblasts
Room: Ballroom 1-3

Speaker 2 of 8
Dean Sheppard, University of California, San Francisco, USA
Molecular Signatures of Collagen-Producing Cells in Multiple Models of Pathologic Tissue Fibrosis

Wednesday, March 29 | 8:00AM - 11:15AM
Amplifying Fibrosis: Activation of Fibrogenic Myofibroblasts
Room: Ballroom 1-3

Speaker 3 of 8
Rebecca G. Wells, University of Pennsylvania, USA
Fibrosis in the Extrahepatic Bile Ducts


Wednesday, March 29 | 8:00AM - 11:15AM
Amplifying Fibrosis: Activation of Fibrogenic Myofibroblasts
Room: Ballroom 1-3


Coffee Break

Wednesday, March 29 | 8:00AM - 11:15AM
Amplifying Fibrosis: Activation of Fibrogenic Myofibroblasts
Room: Ballroom 1-3

Speaker 5 of 8
David A. Brenner, University of California, San Diego, USA
Origin of Myofibroblasts in Fibrotic Liver

Wednesday, March 29 | 8:00AM - 11:15AM
Amplifying Fibrosis: Activation of Fibrogenic Myofibroblasts
Room: Ballroom 1-3

Speaker 6 of 8
Lester F. Lau, University of Illinois at Chicago, USA
The Matricellular Protein CCN1 in Tissue Injury Repair

Wednesday, March 29 | 8:00AM - 11:15AM
Amplifying Fibrosis: Activation of Fibrogenic Myofibroblasts
Room: Ballroom 1-3

Speaker 7 of 8
Chih-Wei Chen, Friedrich-Alexander-University Erlangen-Nuremberg, Germany
Short Talk: Wnt5a Promotes Tissue Fibrosis by PCP-Dependent Activation of Latent TGFbeta

Wednesday, March 29 | 8:00AM - 11:15AM
Amplifying Fibrosis: Activation of Fibrogenic Myofibroblasts
Room: Ballroom 1-3

Speaker 8 of 8
Resat Cinar, NIAAA, National Institutes of Health, USA
Short Talk: Cannabinoid CB1 Receptor Overactivity Contributes to the Pathogenesis of IPF and its Dual-Targeting with
Inducible Nitric Oxide Synthase Improves Anti-Fibrotic Efficacy


Wednesday, March 29 | 11:15AM - 5:00PM
On Own for Lunch


Wednesday, March 29 | 11:15AM - 1:00PM
Poster Setup
Room: Superior/Superior Lobby/Wasatch


Wednesday, March 29 | 1:00PM - 10:00PM
Poster Viewing
Room: Superior/Superior Lobby/Wasatch


Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 2
Room: Ballroom 1-3

Speaker 1 of 7
* Rebecca G. Wells, University of Pennsylvania, USA

Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 2
Room: Ballroom 1-3

Speaker 2 of 7
Scott M. MacDonnell, Regeneron Pharmaceuticals, Inc., USA
Identification of Distinct Cell Populations from Fibrotic Mouse Kidneys using Single Cell Sequencing

Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 2
Room: Ballroom 1-3

Speaker 3 of 7
Sunny Kataria, Institute for Stem Cell Biology and Regenerative Medicine, India
Cellular and Molecular Heterogeneity of Fibroblast Responses in Mouse Model of Dermal Fibrosis 

Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 2
Room: Ballroom 1-3

Speaker 4 of 7
Guobao Chen, Johns Hopkins University, USA
IL-17A-Driven Post-Cardiac Injury Remodeling is Dependent on its Signaling to Sca-1+ Cardiac Fibroblasts

Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 2
Room: Ballroom 1-3

Speaker 5 of 7
Richard Lee Gieseck III, NIAID, National Institutes of Health, USA
Enhanced Protection from Fibrosis and Inflammation by Dual-Blockade of IL-13 and IFNgamma

Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 2
Room: Ballroom 1-3

Speaker 6 of 7
Kevin M. Hart, NIAID, National Institutes of Health, USA
Type-2 Immunity is Protective in Metabolic Disease but Exacerbates NAFLD Collaboratively with TGF-Beta

Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 2
Room: Ballroom 1-3

Speaker 7 of 7
Greg S. Gojanovich, University of Hawaii, USA
Neurofibromin 1 Loss in Tcf21+ Fibroblasts Accelerates Heart Failure Following TAC

Wednesday, March 29 | 4:30PM - 5:00PM
Coffee Available
Room: Ballroom Lobby


Wednesday, March 29 | 5:00PM - 7:00PM
Tumor-Associated Stroma: Parallels with Fibrosis
Room: Ballroom 1-3

Speaker 1 of 5
* Dean Sheppard, University of California, San Francisco, USA

Wednesday, March 29 | 5:00PM - 7:00PM
Tumor-Associated Stroma: Parallels with Fibrosis
Room: Ballroom 1-3

Speaker 2 of 5
Gian Paolo Dotto, University of Lausanne, Switzerland
Multistep Cancer-Associated Fibroblast Activation: A Notch/CSL-Gli Regulatory Axis

Wednesday, March 29 | 5:00PM - 7:00PM
Tumor-Associated Stroma: Parallels with Fibrosis
Room: Ballroom 1-3

Speaker 3 of 5
Andrew D. Rhim, University of Michigan Medical School, USA
Pancreatic Cancer Stroma: A Loud, Crowded, and Complex Field

Wednesday, March 29 | 5:00PM - 7:00PM
Tumor-Associated Stroma: Parallels with Fibrosis
Room: Ballroom 1-3

Speaker 4 of 5
Shuang Liang, University of California, San Diego, USA
Short Talk: NADPH Oxidase 1 Promotes the Development of Hepatocellular Carcinoma

Wednesday, March 29 | 5:00PM - 7:00PM
Tumor-Associated Stroma: Parallels with Fibrosis
Room: Ballroom 1-3

Speaker 5 of 5
Valerie LeBleu, MD Anderson Cancer Center, USA
Short Talk: Functional Role of Tumor Immunity and Fibrosis in Pancreas Cancer

Wednesday, March 29 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Superior/Superior Lobby/Wasatch
No registration fees are used to fund alcohol served at this function.

Wednesday, March 29 | 7:30PM - 10:00PM
Poster Session 3
Room: Superior/Superior Lobby/Wasatch


Thursday, March 30 | 7:00AM - 8:00AM
Breakfast
Room: Golden Cliff/Eagles


Thursday, March 30 | 8:00AM - 11:30AM
Halting Fibrosis: Inducing Regression of Fibrosis
Room: Ballroom 1-3

Speaker 1 of 8
* Katalin Susztak, University of Pennsylvania, USA

Thursday, March 30 | 8:00AM - 11:30AM
Halting Fibrosis: Inducing Regression of Fibrosis
Room: Ballroom 1-3

Speaker 2 of 8
Tatiana Kisseleva, University of California, San Diego, USA
Myofibroblast Reversion to an Inactive Phenotype during Regression of Liver Fibrosis

Thursday, March 30 | 8:00AM - 11:30AM
Halting Fibrosis: Inducing Regression of Fibrosis
Room: Ballroom 1-3

Speaker 3 of 8
David Lagares, Massachusetts General Hospital, USA
Mitochondrial Priming by Matrix Stiffness Sensitizes Myofibroblasts to BH3 Mimetic-Induced Apoptosis in Scleroderma Fibrosis

Thursday, March 30 | 8:00AM - 11:30AM
Halting Fibrosis: Inducing Regression of Fibrosis
Room: Ballroom 1-3


Coffee Break

Thursday, March 30 | 8:00AM - 11:30AM
Halting Fibrosis: Inducing Regression of Fibrosis
Room: Ballroom 1-3

Speaker 5 of 8
Gyongyi Szabo, University of Massachusetts Medical School, USA
Inter-Relationship Between TLR Signaling and Inflammasome Activation in NASH

Thursday, March 30 | 8:00AM - 11:30AM
Halting Fibrosis: Inducing Regression of Fibrosis
Room: Ballroom 1-3

Speaker 6 of 8
Jorge Moscat, Sanford Burnham Prebys Institute, USA
Control of Fibrosis and Inflammation by Stromal p62 in Tumor Progression

Thursday, March 30 | 8:00AM - 11:30AM
Halting Fibrosis: Inducing Regression of Fibrosis
Room: Ballroom 1-3

Speaker 7 of 8
Holger Willenbring, University of California, San Francisco, USA
Hepatic Reprogramming of Myofibroblasts as a Therapeutic Strategy for Liver Fibrosis

Thursday, March 30 | 8:00AM - 11:30AM
Halting Fibrosis: Inducing Regression of Fibrosis
Room: Ballroom 1-3

Speaker 8 of 8
Fiona E. McCann, Oxford University, UK
Short Talk: Localised Inhibition of Histone Acetylation May Offer a Novel Therapeutic Strategy to Down Regulate the
Myofibroblast Phenotype in Dupuytren's Disease 


Thursday, March 30 | 11:30AM - 5:00PM
On Own for Lunch


Thursday, March 30 | 4:30PM - 5:00PM
Coffee Available
Room: Ballroom Lobby


Thursday, March 30 | 5:00PM - 6:45PM
New Directions in Patient Evaluation and Treatment
Room: Ballroom 2-3

Speaker 1 of 4
* Gyongyi Szabo, University of Massachusetts Medical School, USA

Thursday, March 30 | 5:00PM - 6:45PM
New Directions in Patient Evaluation and Treatment
Room: Ballroom 2-3

Speaker 2 of 4
Robert Lafyatis, University of Pittsburgh Medical Center, USA
Fibroblast and Macrophage Transcriptomes Indicate Pathogenic Pathways in Systemic Sclerosis

Thursday, March 30 | 5:00PM - 6:45PM
New Directions in Patient Evaluation and Treatment
Room: Ballroom 2-3

Speaker 3 of 4
David Shapiro, Intercept Pharmaceuticals, Inc., USA
Therapeutic Bile Acids - Longer Levers in Liver Disease?

Thursday, March 30 | 5:00PM - 6:45PM
New Directions in Patient Evaluation and Treatment
Room: Ballroom 2-3

Speaker 4 of 4
Jeremy S. Duffield, Vertex Pharmaceuticals, USA
MicroRNAs as Potential Therapeutic Targets in Fibrotic Diseases

Thursday, March 30 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Ballroom 2-3


Thursday, March 30 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Ballroom 1-2
No registration fees are used to fund alcohol served at this function.

Thursday, March 30 | 8:00PM - 11:00PM
Entertainment
Room: Ballroom 1-2
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, March 30 | 8:00PM - 11:00PM
Cash Bar
Room: Ballroom 1-2


Friday, March 31 | 10:24AM - 10:24AM
Departure


*Session Chair
†Invited, not yet responded.