Web Desc
HIV Vaccines
Organizer(s): Andrew B. Ward, Penny L. Moore and Robin Shattock
Date: March 26 - 30, 2017
Location: Sheraton Steamboat Resort, Steamboat Springs, CO, USA
Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation.
Summary of Meeting:
Despite great progress in preventing and treating HIV, new infections continue to plague communities around the world, and the need for an HIV vaccine is as urgent as ever. Several large cohorts of HIV-infected individuals have enabled tremendous advances over the past five years in understanding immune responses to natural HIV infection. These advances have included the isolation of broad and potent anti-HIV antibodies, defining their developmental pathways, the generation of native-like Env trimers for immunization, and high-resolution structures of the envelope glycoprotein in complex with bnAbs. By 2017, many of these discoveries will have enabled new concepts to transition into human clinical trials, including passive monoclonal antibody therapy and novel immunization approaches. These platforms, incorporating improved technology for monitoring immune responses, will drive major advances in the vaccine field. This HIV Vaccines meeting will present the latest results from human clinical studies, along with the cutting-edge basic science behind such trials to highlight approaches that may lead to an HIV vaccine, and also reveal the molecular underpinnings of B and T cell-mediated immunity.
Global Health Travel Award Deadline: October 25 2016
Scholarship Deadline: November 29 2016
Discounted Abstract Deadline: November 29 2016
Abstract Deadline: January 10 2017
Discounted Registration Deadline: January 24 2017
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Bill & Melinda Gates Foundation
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Kymab Limited
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI129592-01
Funding for this conference was made possible (in part) by AI29592-01 from the National Institute of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, March 26 | 4:00PM - 8:00PM
Arrival and Registration
Room: Foyer


Sunday, March 26 | 6:00PM - 8:00PM
Welcome Mixer
Room: Foyer
No registration fees are used to fund alcohol served at this function.

Monday, March 27 | 7:00AM - 8:00AM
Breakfast
Room: Foyer/Rainbow/Twilight


Monday, March 27 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Storm Peak/Mt. Werner

Speaker 1 of 2
* Andrew B. Ward, The Scripps Research Institute, USA

Monday, March 27 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Storm Peak/Mt. Werner

Speaker 2 of 2
Nina D. Russell, Bill & Melinda Gates Foundation, USA
HIV Vaccines - The Year in Review

Monday, March 27 | 9:00AM - 11:30AM
New Paradigms in Active and Passive Immunization
Room: Storm Peak/Mt. Werner

Speaker 1 of 7
* Andrew B. Ward, The Scripps Research Institute, USA

Monday, March 27 | 9:00AM - 11:30AM
New Paradigms in Active and Passive Immunization
Room: Storm Peak/Mt. Werner

Speaker 2 of 7
Michel C. Nussenzweig, HHMI/Rockefeller University, USA
Passive Protection with 3BNC117

Monday, March 27 | 9:00AM - 11:30AM
New Paradigms in Active and Passive Immunization
Room: Storm Peak/Mt. Werner

Speaker 3 of 7
K.Rachael Parks, University of Washington, USA
Short Talk: Optimizing the Expansion of Primary VRC01 Antibody Responses by Germline-Targeting Immunogens

Monday, March 27 | 9:00AM - 11:30AM
New Paradigms in Active and Passive Immunization
Room: Storm Peak/Mt. Werner


Coffee Break

Monday, March 27 | 9:00AM - 11:30AM
New Paradigms in Active and Passive Immunization
Room: Storm Peak/Mt. Werner

Speaker 5 of 7
Todd C. Bradley, Children's Mercy Kansas City, USA
Short Talk: Immune Checkpoint Inhibitor Co-Administration with HIV Env Modifies the Antibody Repertoire

Monday, March 27 | 9:00AM - 11:30AM
New Paradigms in Active and Passive Immunization
Room: Storm Peak/Mt. Werner

Speaker 6 of 7
Alejandro Balazs, Massachusetts General Hospital, USA
Development of Vectored ImmunoProphylaxis and ImmunoTherapy against HIV Infection


Monday, March 27 | 9:00AM - 11:30AM
New Paradigms in Active and Passive Immunization
Room: Storm Peak/Mt. Werner

Speaker 7 of 7
Jonah B. Sacha, Oregon Health & Science University, USA
Cross-Species CMV Vaccination Reveals Viral Determinants for Induction of Non-Classical MHC-E-Restricted T Cells

Monday, March 27 | 11:30AM - 5:00PM
On Own for Lunch


Monday, March 27 | 11:30AM - 1:00PM
Poster Setup
Room: Sunshine/Rainbow/Twilight


Monday, March 27 | 1:00PM - 10:00PM
Poster Viewing
Room: Sunshine/Rainbow/Twilight


Monday, March 27 | 2:30PM - 4:30PM
Workshop 1: Structural and Mechanistic Insights into Neutral
ization
Room: Storm Peak/Mt. Werner

Speaker 1 of 8
* Ian A. Wilson, The Scripps Research Institute, USA

Monday, March 27 | 2:30PM - 4:30PM
Workshop 1: Structural and Mechanistic Insights into Neutral
ization
Room: Storm Peak/Mt. Werner

Speaker 2 of 8
Kimmo Rantalainen, The Scripps Research Institute, USA
Structure of Full-Length HIV Envelope in Complex with PGT151

Monday, March 27 | 2:30PM - 4:30PM
Workshop 1: Structural and Mechanistic Insights into Neutral
ization
Room: Storm Peak/Mt. Werner

Speaker 3 of 8
Raiees Andrabi, The Scripps Research Institute, USA
Glycans as Anchors for Inducing HIV Broadly Neutralizing Antibodies

Monday, March 27 | 2:30PM - 4:30PM
Workshop 1: Structural and Mechanistic Insights into Neutral
ization
Room: Storm Peak/Mt. Werner

Speaker 4 of 8
Sasha Murrell, The Scripps Research Institute, USA
Structural Investigation of A Novel Family of Broadly Neutralizing Antibodies that Target the N332 Supersite in HIV Env

Monday, March 27 | 2:30PM - 4:30PM
Workshop 1: Structural and Mechanistic Insights into Neutral
ization
Room: Storm Peak/Mt. Werner

Speaker 5 of 8
Evan M. Cale, NIAID, National Institutes of Health, USA
Isolation of an HIV-1-Specific Neutralizing Antibody Lineage with Similar Characteristics to the gp41-gp120 Interface-Binding Antibody 35O22

Monday, March 27 | 2:30PM - 4:30PM
Workshop 1: Structural and Mechanistic Insights into Neutral
ization
Room: Storm Peak/Mt. Werner

Speaker 6 of 8
Gwo-Yu Chuang, NIAID, National Institutes of Health, USA
Optimization of HIV-1 Broadly Neutralizing Antibodies by Surface-Matrix Scanning

Monday, March 27 | 2:30PM - 4:30PM
Workshop 1: Structural and Mechanistic Insights into Neutral
ization
Room: Storm Peak/Mt. Werner

Speaker 7 of 8
Till Schoofs, Rockefeller University, USA
Antibody 10-1074 Suppresses Viremia in HIV-1 Infected Individuals

Monday, March 27 | 2:30PM - 4:30PM
Workshop 1: Structural and Mechanistic Insights into Neutral
ization
Room: Storm Peak/Mt. Werner

Speaker 8 of 8
Ryan Meyerhoff, Duke University, USA
Induction of Antibodies Targeting the V3 Glycan Broadly Neutralizing Epitope in Rhesus Macaques using a Synthetic Immunogen

Monday, March 27 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Monday, March 27 | 5:00PM - 7:15PM
Lessons from Animal Vaccinations
Room: Storm Peak/Mt. Werner

Speaker 1 of 6
* Rogier W. Sanders, University of Amsterdam and Weill Cornell Medical College, Netherlands

Monday, March 27 | 5:00PM - 7:15PM
Lessons from Animal Vaccinations
Room: Storm Peak/Mt. Werner

Speaker 2 of 6
Paul Kellam, Kymab, UK
Mice with Fully Human Immunoglobulin Loci and their Use for Predictive Vaccine Antigen Discovery

Monday, March 27 | 5:00PM - 7:15PM
Lessons from Animal Vaccinations
Room: Storm Peak/Mt. Werner

Speaker 3 of 6
Maria Blasi, Duke University School of Medicine, USA
Short Talk: Sequential Immunizations with an Integrase Defective LentiVector Induce Higher Magnitude and More Durable Antibody Responses than DNA and Protein Based Vaccine Regimens

Monday, March 27 | 5:00PM - 7:15PM
Lessons from Animal Vaccinations
Room: Storm Peak/Mt. Werner

Speaker 4 of 6
Nancy L. Haigwood, Oregon Health & Science University, USA
Passive and Active Studies in Primate Models to Inform HIV Vaccines

Monday, March 27 | 5:00PM - 7:15PM
Lessons from Animal Vaccinations
Room: Storm Peak/Mt. Werner

Speaker 5 of 6
Peter D. Kwong, NIAID, National Institutes of Health, USA
Short Talk: Peptide-Coupled Carrier Proteins to Focus the Immune Response to an HIV-1 Site of Vulnerability

Monday, March 27 | 5:00PM - 7:15PM
Lessons from Animal Vaccinations
Room: Storm Peak/Mt. Werner

Speaker 6 of 6
Andrew B. Ward, The Scripps Research Institute, USA
Structures of HIV Neutralizing Antibodies Elicited from Animal Immunization with SOSIP Env Trimers


Monday, March 27 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Foyer/Rainbow/Twilight
No registration fees are used to fund alcohol served at this function.

Monday, March 27 | 7:30PM - 10:00PM
Poster Session 1
Room: Sunshine/Rainbow/Twilight


Tuesday, March 28 | 7:00AM - 8:00AM
Breakfast
Room: Foyer/Rainbow/Twilight


Tuesday, March 28 | 8:00AM - 11:15AM
B and T Cells
Room: Storm Peak/Mt. Werner

Speaker 1 of 8
* Barton F. Haynes, Duke University Medical Center, USA

Tuesday, March 28 | 8:00AM - 11:15AM
B and T Cells
Room: Storm Peak/Mt. Werner

Speaker 2 of 8
Gunilla B. Karlsson Hedestam, Karolinska Institutet, Sweden
Individualized Profiling of Germline V Genes and Application to Env Trimer Immunogenicity Studies in NHPs

Tuesday, March 28 | 8:00AM - 11:15AM
B and T Cells
Room: Storm Peak/Mt. Werner

Speaker 3 of 8
Thomas B. Kepler, Boston University, USA
B Cell Clonal Dynamics during Sequential Immunizations

Tuesday, March 28 | 8:00AM - 11:15AM
B and T Cells
Room: Storm Peak/Mt. Werner

Speaker 4 of 8
Sabrina Helmold, NCI, National Institutes of Health, USA
Short Talk:Dynamics of T Follicular Helper Cells and Germinal Center B Cells over the Course of Vaccination in Rhesus Macaques

Tuesday, March 28 | 8:00AM - 11:15AM
B and T Cells
Room: Storm Peak/Mt. Werner


Coffee Break

Tuesday, March 28 | 8:00AM - 11:15AM
B and T Cells
Room: Storm Peak/Mt. Werner

Speaker 6 of 8
Stephen J. Kent, University of Melbourne, Australia
ADCC and Beyond

Tuesday, March 28 | 8:00AM - 11:15AM
B and T Cells
Room: Storm Peak/Mt. Werner

Speaker 7 of 8
Colin Havenar-Daughton, Vir Biotechnology, USA
Short Talk: Germinal Centers Correlate with HIV Trimer-Induced Neutralizing Antibody Induction and Inform Improved
Immunization Scheduling for Maximizing HIV Neutralizing Antibody Responses


Tuesday, March 28 | 8:00AM - 11:15AM
B and T Cells
Room: Storm Peak/Mt. Werner

Speaker 8 of 8
Marie Pancera, Fred Hutchinson Cancer Research Center, USA
Short Talk: Anti-Idiotypic Antibodies against Inferred Germline b12, a CD4 Binding Site Antibody, as Toosl for Detection of Naïve B Cells Expressing Germline b12-like Precursors and Rational Immunogen Design

Tuesday, March 28 | 11:15AM - 5:00PM
On Own for Lunch


Tuesday, March 28 | 11:15AM - 1:00PM
Poster Setup
Room: Sunshine/Rainbow/Twilight


Tuesday, March 28 | 11:30AM - 1:00PM
Hands-On Computer Session on Los Alamos Sequence Database
Room: Skyline
HIV Database Workshop presented by Los Alamos National Laboratory staff Topics include:
- HIV Sequence Database
- Bioinformatics tools that have general application

Users can register for either or both workshops. Bring your own laptop.

Tuesday, March 28 | 1:00PM - 10:00PM
Poster Viewing
Room: Sunshine/Rainbow/Twilight


Tuesday, March 28 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Tuesday, March 28 | 5:00PM - 7:00PM
Adjuvants and Delivery Systems
Room: Storm Peak/Mt. Werner

Speaker 1 of 5
* Robin Shattock, Imperial College London, UK

Tuesday, March 28 | 5:00PM - 7:00PM
Adjuvants and Delivery Systems
Room: Storm Peak/Mt. Werner

Speaker 2 of 5
Carl R. Alving, Walter Reed Army Institute of Research, USA
Rational Basis for Creation and Selection of Adjuvant Formulations for HIV-1 Vaccines

Tuesday, March 28 | 5:00PM - 7:00PM
Adjuvants and Delivery Systems
Room: Storm Peak/Mt. Werner

Speaker 3 of 5
Mark T. Orr, Infectious Disease Research Institute, USA
Tailoring Vaccine Responses with Formulated TLR Agonist Adjuvants

Tuesday, March 28 | 5:00PM - 7:00PM
Adjuvants and Delivery Systems
Room: Storm Peak/Mt. Werner

Speaker 4 of 5
James J. Kobie, University of Rochester, Medical Center, USA
Short Talk: IL-33 Enhances the Induction, Durability, and Breadth of the Antibody Response to a DNA/Protein-Based HIV Env Vaccine

Tuesday, March 28 | 5:00PM - 7:00PM
Adjuvants and Delivery Systems
Room: Storm Peak/Mt. Werner

Speaker 5 of 5
Darrell J. Irvine, Massachusetts Institute of Technology, USA
Regulation of the Germinal Center Reaction and Humoral Response by Vaccine Kinetics

Tuesday, March 28 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Foyer/Rainbow/Twilight
No registration fees are used to fund alcohol served at this function.

Tuesday, March 28 | 7:30PM - 10:00PM
Poster Session 2
Room: Sunshine/Rainbow/Twilight


Wednesday, March 29 | 7:00AM - 8:00AM
Breakfast
Room: Foyer/Rainbow/Twilight


Wednesday, March 29 | 8:00AM - 11:15AM
Human Clinical Trials
Room: Storm Peak/Mt. Werner

Speaker 1 of 8
* Gabriella Scarlatti, Global HIV Vaccine Enterprise, USA

Wednesday, March 29 | 8:00AM - 11:15AM
Human Clinical Trials
Room: Storm Peak/Mt. Werner

Speaker 2 of 8
Mark B. Feinberg, IAVI International AIDS Vaccine Initiative, USA
Expediting Ebola Vaccine Development and Implications for HIV Vaccine R&D Efforts

Wednesday, March 29 | 8:00AM - 11:15AM
Human Clinical Trials
Room: Storm Peak/Mt. Werner

Speaker 3 of 8
Alberto Cagigi, NIAID, National Institutes of Health, USA
Short Talk: Potential for Immunization with eOD-GT8 to Drive B Cell Responses Toward the Production of CD4bs Antibodies

Wednesday, March 29 | 8:00AM - 11:15AM
Human Clinical Trials
Room: Storm Peak/Mt. Werner

Speaker 4 of 8
Barton F. Haynes, Duke University Medical Center, USA
Testing the Concept of B Cell Lineage Immunogen Design for Initiation of Broadly Neutralizing B Cell Lineages in Human Clinical Trials

Wednesday, March 29 | 8:00AM - 11:15AM
Human Clinical Trials
Room: Storm Peak/Mt. Werner


Coffee Break

Wednesday, March 29 | 8:00AM - 11:15AM
Human Clinical Trials
Room: Storm Peak/Mt. Werner

Speaker 6 of 8
Kelly E. Seaton, Duke Human Vaccine Institute, USA
Short Talk: Individual-level meta-analysis of HIV-1 Vaccine Elicited Mucosal Antibodies in Human Volunteers

Wednesday, March 29 | 8:00AM - 11:15AM
Human Clinical Trials
Room: Storm Peak/Mt. Werner

Speaker 7 of 8
M. Juliana McElrath, Fred Hutchinson Cancer Research Center, USA
Induction of HIV-Specific Immunity with Recent Clinical Vaccine Approaches

Wednesday, March 29 | 8:00AM - 11:15AM
Human Clinical Trials
Room: Storm Peak/Mt. Werner

Speaker 8 of 8
Robin Shattock, Imperial College London, UK
DNA Vaccination for Experimental Medicine Trials of HIV Vaccines

Wednesday, March 29 | 11:15AM - 5:00PM
On Own for Lunch


Wednesday, March 29 | 11:15AM - 1:00PM
Poster Setup
Room: Sunshine/Rainbow/Twilight


Wednesday, March 29 | 11:30AM - 1:00PM
Hands-On Computer Session on Los Alamos Immunology Database
Room: Skyline
HIV Database Workshop presented by Los Alamos National Laboratory staff Topics include:
- HIV Immunology Database
- Immunology and vaccine design tools that have general application.

Wednesday, March 29 | 1:00PM - 10:00PM
Poster Viewing
Room: Sunshine/Rainbow/Twilight


Wednesday, March 29 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Wednesday, March 29 | 5:00PM - 7:00PM
Lessons from Infection
Room: Storm Peak/Mt. Werner

Speaker 1 of 5
* Penny L. Moore, University of the Witwatersrand and National Institute for Communicable Diseases, South Africa

Wednesday, March 29 | 5:00PM - 7:00PM
Lessons from Infection
Room: Storm Peak/Mt. Werner

Speaker 2 of 5
Thumbi Ndung'u, University of KwaZulu-Natal, South Africa
Antiretroviral Treatment of Acute HIV Infection and the Prospect for a Functional Cure

Wednesday, March 29 | 5:00PM - 7:00PM
Lessons from Infection
Room: Storm Peak/Mt. Werner

Speaker 3 of 5
Christiane Moog, INSERM and Université of Strasbourg, France
Short Talk: Unexpected Antibody Isotypes and Neutralizing Profile in Patients Controlling HIV

Wednesday, March 29 | 5:00PM - 7:00PM
Lessons from Infection
Room: Storm Peak/Mt. Werner

Speaker 4 of 5
Julie M. Overbaugh, Fred Hutchinson Cancer Research Center, USA
Unique Aspects of the Infant HIV-Specific Neutralizing Antibody Response

Wednesday, March 29 | 5:00PM - 7:00PM
Lessons from Infection
Room: Storm Peak/Mt. Werner

Speaker 5 of 5
Alexandra Trkola, University of Zürich, Switzerland
Determinants of bnAb Development

Wednesday, March 29 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Foyer/Rainbow/Twilight
No registration fees are used to fund alcohol served at this function.

Wednesday, March 29 | 7:30PM - 10:00PM
Poster Session 3
Room: Sunshine/Rainbow/Twilight


Thursday, March 30 | 7:00AM - 8:00AM
Breakfast
Room: Foyer/Rainbow/Twilight


Thursday, March 30 | 8:00AM - 11:15AM
Broadly Neutralizing Antibodies: Hurdles and Opportunities
Room: Storm Peak/Mt. Werner

Speaker 1 of 9
* Alexandra Trkola, University of Zürich, Switzerland

Thursday, March 30 | 8:00AM - 11:15AM
Broadly Neutralizing Antibodies: Hurdles and Opportunities
Room: Storm Peak/Mt. Werner

Speaker 2 of 9
Penny L. Moore, University of the Witwatersrand and National Institute for Communicable Diseases, South Africa
Longitudinal Studies of Neutralizing Antibody Development in the CAPRISA Cohort

Thursday, March 30 | 8:00AM - 11:15AM
Broadly Neutralizing Antibodies: Hurdles and Opportunities
Room: Storm Peak/Mt. Werner

Speaker 3 of 9
Kshitij Wagh, Los Alamos National Laboratory, USA
Short Talk: Env Glycan Holes Negatively Impact Development of Heterologous Neutralization Breadth in HIV-1 Infections

Thursday, March 30 | 8:00AM - 11:15AM
Broadly Neutralizing Antibodies: Hurdles and Opportunities
Room: Storm Peak/Mt. Werner

Speaker 4 of 9
Brandon DeKosky, University of Kansas, USA
Short Talk: High-Throughput Paired Heavy and Light Chain Analyses of HIV Broadly Neutralizing Antibody Lineages

Thursday, March 30 | 8:00AM - 11:15AM
Broadly Neutralizing Antibodies: Hurdles and Opportunities
Room: Storm Peak/Mt. Werner


Coffee Break

Thursday, March 30 | 8:00AM - 11:15AM
Broadly Neutralizing Antibodies: Hurdles and Opportunities
Room: Storm Peak/Mt. Werner

Speaker 6 of 9
Elise Landais, International AIDS Vaccine Initiative, USA
Broadly Neutralizing Antibodies to HIV-1: Lessons from Protocol C Studies

Thursday, March 30 | 8:00AM - 11:15AM
Broadly Neutralizing Antibodies: Hurdles and Opportunities
Room: Storm Peak/Mt. Werner

Speaker 7 of 9
Wilton B. Williams, Duke University, USA
Short Talk: SHIV-CH505 Infection of Rhesus macaques Recapitulates HIV-1 Env-Antibody Evolution in Humans

Thursday, March 30 | 8:00AM - 11:15AM
Broadly Neutralizing Antibodies: Hurdles and Opportunities
Room: Storm Peak/Mt. Werner

Speaker 8 of 9
Samantha Leigh Grimley, San Diego Biomedical Research Institute, USA
Short Talk: Striking Impact of HIV-1 Envelope Glycoengineering on BnAb Sensitivities

Thursday, March 30 | 8:00AM - 11:15AM
Broadly Neutralizing Antibodies: Hurdles and Opportunities
Room: Storm Peak/Mt. Werner

Speaker 9 of 9
Nicole A. Doria-Rose, NIAID, National Institutes of Health, USA
Tracing Virus-Antibody Co-Evolution of MPER-directed Neutralizing Antibodies

Thursday, March 30 | 11:15AM - 5:00PM
On Own for Lunch


Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: Testing Vaccine Platforms in Animals
Room: Storm Peak/Mt. Werner

Speaker 1 of 8
* Richard T. Wyatt, IAVI Neutralizing Antibody Center, The Scripps Research Institute, USA

Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: Testing Vaccine Platforms in Animals
Room: Storm Peak/Mt. Werner

Speaker 2 of 8
Diane L. Bolton, US Military HIV Research Program, WRAIR, USA
Immunogenicity and Efficacy of MVA, gp145 Vaccination Against Heterologous Tier 2 SHIV C Challenge in Rhesus

Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: Testing Vaccine Platforms in Animals
Room: Storm Peak/Mt. Werner

Speaker 3 of 8
Qifeng Han, Duke University, USA
HIV gp41 Immunodominance Following gp140 Immunization Occurs in Humans but is Not Detected in Rhesus Macaques

Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: Testing Vaccine Platforms in Animals
Room: Storm Peak/Mt. Werner

Speaker 4 of 8
Mattias Forsell, Umeå University, Sweden
Autologous But Not Heterologous Antibodies Negatively Regulate Subunit-Specific Germinal Center B Cell Responses to the HIV-1 Envelope Glycoproteins

Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: Testing Vaccine Platforms in Animals
Room: Storm Peak/Mt. Werner

Speaker 5 of 8
Matthias Georg Pauthner, The Scripps Research Institute, USA
Optimized Env Trimer Immunization Parameters Amplify Onset, Magnitude and Consistency of Autologous Tier 2 Neutralizing Antibody Development in Nonhuman Primates

Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: Testing Vaccine Platforms in Animals
Room: Storm Peak/Mt. Werner

Speaker 6 of 8
Paola Andrea Martinez Murillo, Karolinska Institutet, Sweden
F9, A New Class of Antibody that Neutralizes Autologous Tier 2 Viruses in Rhesus Immunized with Liposome Conjugated Well-Ordered Trimers

Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: Testing Vaccine Platforms in Animals
Room: Storm Peak/Mt. Werner

Speaker 7 of 8
Jose Maximiliano Medina-Ramírez, University of Amsterdam, Netherlands
A Native-Like Envelope Trimer with Enhanced Binding of Inferred Germline Precursors of Broadly Neutralizing HIV-1 Antibodies

Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: Testing Vaccine Platforms in Animals
Room: Storm Peak/Mt. Werner

Speaker 8 of 8
James E. Voss, The Scripps Research Institute, USA
Reproducible Elicitation of HIV Envelope V2-Apex Focused Neutralizing Antibodies in Rabbits

Thursday, March 30 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Thursday, March 30 | 5:00PM - 6:45PM
Immunogen Platforms
Room: Storm Peak/Mt. Werner

Speaker 1 of 4
* Peter D. Kwong, NIAID, National Institutes of Health, USA

Thursday, March 30 | 5:00PM - 6:45PM
Immunogen Platforms
Room: Storm Peak/Mt. Werner

Speaker 2 of 4
Jon Steichen, The Scripps Research Institute, USA
HIV Vaccine Design to Target Germline Precursors of N332-Dependent Broadly Neutralizing Antibodies

Thursday, March 30 | 5:00PM - 6:45PM
Immunogen Platforms
Room: Storm Peak/Mt. Werner

Speaker 3 of 4
Neil P. King, University of Washington, USA
Design of Novel Self-Assembling Protein Nanomaterials as Next-Generation Vaccine Scaffolds

Thursday, March 30 | 5:00PM - 6:45PM
Immunogen Platforms
Room: Storm Peak/Mt. Werner

Speaker 4 of 4
Rogier W. Sanders, University of Amsterdam and Weill Cornell Medical College, Netherlands
Inducing HIV-1 Neutralizing Antibodies with Native-Like Envelope Trimers

Thursday, March 30 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Storm Peak/Mt. Werner


Thursday, March 30 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Foyer/Rainbow/Twilight
No registration fees are used to fund alcohol served at this function.

Thursday, March 30 | 8:00PM - 11:00PM
Entertainment
Room: Sunshine
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, March 30 | 8:00PM - 11:00PM
Cash Bar
Room: Sunshine


Friday, March 31 | 10:25AM - 10:25AM
Departure


*Session Chair.