Web Desc
Cellular Stress Responses and Infectious Agents
Organizer(s): Margo A. Brinton, Sandra K. Weller and Beth Levine
Date: December 04 - 08, 2016
Location: Eldorado Hotel & Spa, Santa Fe, NM, USA
Supported by the Directors' Fund
Summary of Meeting:
This conference will bring together cell biologists studying various cellular stress responses and researchers interested in how various infectious agents activate and manipulate host cellular stress responses. Examples of cellular stress responses activated by infectious agents are: the stress granule response, the unfolded protein response, the DNA damage response, responses to oxidative stress and metabolic stress, autophagy, and other protein quality control responses. Many of these cellular homeostatic mechanisms function as part of innate and intrinsic defense mechanisms to counteract infections. Various infectious agents have evolved to subvert and manipulate many of these anti-pathogen mechanisms by utilizing, evading or inactivating components of these cellular pathways. The study of interactions between infectious agents and these pathways provides new insights about cellular stress responses and identifies new targets for the development of novel therapies for the treatment of infectious diseases.
Scholarship Deadline: August 4 2016
Discounted Abstract Deadline: August 4 2016
Abstract Deadline: September 12 2016
Discounted Registration Deadline: October 4 2016
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI126782-01
Funding for this conference was made possible (in part) by 1R13AI126782-01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, December 04 | 4:00PM - 8:00PM
Arrival and Registration
Room: Eldorado Lounge


Sunday, December 04 | 6:00PM - 8:00PM
Welcome Mixer
Room: Eldorado Lounge
No registration fees are used to fund alcohol served at this function.

Monday, December 05 | 7:30AM - 8:30AM
Breakfast
Room: Anasazi Ballroom


Monday, December 05 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Eldorado B

Speaker 1 of 3
* Margo A. Brinton, Georgia State University, USA

Monday, December 05 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Eldorado B

Speaker 2 of 3
* Beth Levine, University of Texas Southwestern Medical Center, USA

Monday, December 05 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Eldorado B

Speaker 3 of 3
David Ron, University of Cambridge, UK
Protein-Folding Homeostasis in the Endoplasmic Reticulum – Some Lessons from Microbes

Monday, December 05 | 9:30AM - 12:00PM
Unfolded Protein Response
Room: Eldorado B

Speaker 1 of 7
* Beth Levine, University of Texas Southwestern Medical Center, USA

Monday, December 05 | 9:30AM - 12:00PM
Unfolded Protein Response
Room: Eldorado B

Speaker 2 of 7
R. Luke Wiseman, The Scripps Research Institute, USA
Regulating Secretory Proteostasis through the Unfolded Protein Response

Monday, December 05 | 9:30AM - 12:00PM
Unfolded Protein Response
Room: Eldorado B


Coffee Break

Monday, December 05 | 9:30AM - 12:00PM
Unfolded Protein Response
Room: Eldorado B

Speaker 4 of 7
Timothy A.J. Haystead, Duke University, USA
Hsp90 Promotes HIV and Chikungunya Virus Replication, Hsp90 Inhibitors are Antiviral

Monday, December 05 | 9:30AM - 12:00PM
Unfolded Protein Response
Room: Eldorado B

Speaker 5 of 7
Claudio Soto, University of Texas Medical School at Houston, USA
The Unfolded Protein Response after Prion Infection

Monday, December 05 | 9:30AM - 12:00PM
Unfolded Protein Response
Room: Eldorado B

Speaker 6 of 7
Timothy E. Audas, Simon Fraser University, Canada
Short Talk: Adaptation to Stressors by Systemic Protein Amyloidogenesis

Monday, December 05 | 9:30AM - 12:00PM
Unfolded Protein Response
Room: Eldorado B

Speaker 7 of 7
Ross Buchan, University of Arizona, USA
Short Talk: Endocytosis is a Key Regulator of TDP-43 Aggregation, Toxicity and Turnover

Monday, December 05 | 12:00PM - 2:30PM
On Own for Lunch


Monday, December 05 | 12:00PM - 1:00PM
Poster Setup
Room: Anasazi Ballroom


Monday, December 05 | 1:00PM - 10:00PM
Poster Viewing
Room: Anasazi Ballroom


Monday, December 05 | 2:30PM - 4:30PM
Workshop 1: Unfolded Protein Response and ER Stress
Room: Eldorado B

Speaker 1 of 7
* Timothy A.J. Haystead, Duke University, USA

Monday, December 05 | 2:30PM - 4:30PM
Workshop 1: Unfolded Protein Response and ER Stress
Room: Eldorado B

Speaker 2 of 7
Mitali Adlakha, University of Connecticut Health Center, USA
HSV-1 Immediate Early Proteins ICP0 and ICP22 Manipulate the Cellular Protein Homeostatic Machinery

Monday, December 05 | 2:30PM - 4:30PM
Workshop 1: Unfolded Protein Response and ER Stress
Room: Eldorado B

Speaker 3 of 7
Vikas Anathy, University of Vermont, Larner College of Medicine, USA
Activation of UPR Transducer ATF6alpha and Increases in PDIA3 is Required for Influenza Propagation and Development of Lung Pathology

Monday, December 05 | 2:30PM - 4:30PM
Workshop 1: Unfolded Protein Response and ER Stress
Room: Eldorado B

Speaker 4 of 7
Ben P. Johnston, Dalhousie University, Canada
KSHV Modulates the IRE1-XBP1 Axis of the Unfolded Protein Response during Lytic Replication

Monday, December 05 | 2:30PM - 4:30PM
Workshop 1: Unfolded Protein Response and ER Stress
Room: Eldorado B

Speaker 5 of 7
Kimberly Kline, Nanyang Technological University, Singapore
Streptolysin-Induced Endoplasmic Reticulum Stress Controls in vivo Biofilm Formation by Group A Streptococcus

Monday, December 05 | 2:30PM - 4:30PM
Workshop 1: Unfolded Protein Response and ER Stress
Room: Eldorado B

Speaker 6 of 7
Charles Grose, University of Iowa, USA
Cellular Stress, Autophagosomes, Amphisomes and Virus Trafficking during Varicella Infection

Monday, December 05 | 2:30PM - 4:30PM
Workshop 1: Unfolded Protein Response and ER Stress
Room: Eldorado B

Speaker 7 of 7
Abagail Rosen, University of Virginia, USA
A Novel, IRE1-Dependent Role for Sigma-1 Receptor in Control of Inflammatory Cytokine Production

Monday, December 05 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Monday, December 05 | 5:00PM - 7:00PM
Stress Granule Response, Modulation of Translation and Innat
e Immunity

Room: Eldorado B

Speaker 1 of 5
* Margo A. Brinton, Georgia State University, USA

Monday, December 05 | 5:00PM - 7:00PM
Stress Granule Response, Modulation of Translation and Innat
e Immunity

Room: Eldorado B

Speaker 2 of 5
Paul J. Anderson, Harvard Medical School, USA
Stress Granules: RNA-centric Signaling Hubs

Monday, December 05 | 5:00PM - 7:00PM
Stress Granule Response, Modulation of Translation and Innat
e Immunity

Room: Eldorado B

Speaker 3 of 5
Richard E. Lloyd, Baylor College of Medicine, USA
Cross-Talk between RNA Granules and Innate Immunity

Monday, December 05 | 5:00PM - 7:00PM
Stress Granule Response, Modulation of Translation and Innat
e Immunity

Room: Eldorado B

Speaker 4 of 5
Craig McCormick, Dalhousie University, Canada
Control of Protein Synthesis in Influenza Virus-Infected Cells

Monday, December 05 | 5:00PM - 7:00PM
Stress Granule Response, Modulation of Translation and Innat
e Immunity

Room: Eldorado B

Speaker 5 of 5
Mena Abdel-Nour, University of Toronto, Canada
Short Talk: The eIF2 alpha Kinase HRI Senses Protein Aggregation and Facilitates Signaling of Cytosolic Innate Immune Receptors

Monday, December 05 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Anasazi Ballroom
No registration fees are used to fund alcohol served at this function.

Monday, December 05 | 7:30PM - 10:00PM
Poster Session 1
Room: Anasazi Ballroom


Tuesday, December 06 | 7:30AM - 8:30AM
Breakfast
Room: Anasazi Ballroom


Tuesday, December 06 | 8:30AM - 11:45AM
Regulation of Stress Responses
Room: Eldorado B

Speaker 1 of 8
* James C. Alwine, University of Pennsylvania School of Medicine, USA

Tuesday, December 06 | 8:30AM - 11:45AM
Regulation of Stress Responses
Room: Eldorado B

Speaker 2 of 8
Carolyn-Ann Robinson, Dalhousie University, Canada
Activation of LXRalpha Inhibits Kaposi’s Sarcoma-Associated Herpesvirus Replication

Tuesday, December 06 | 8:30AM - 11:45AM
Regulation of Stress Responses
Room: Eldorado B

Speaker 3 of 8
Carmen Rivas, Centro Nacional de Biotecnología, Spain
Regulation of Stress Responses by SUMOylation

Tuesday, December 06 | 8:30AM - 11:45AM
Regulation of Stress Responses
Room: Eldorado B


Coffee Break

Tuesday, December 06 | 8:30AM - 11:45AM
Regulation of Stress Responses
Room: Eldorado B

Speaker 5 of 8
Robert H. Silverman, Cleveland Clinic Foundation, USA
The Role of 2’,5’-Oligoadenylate Synthetases in Cellular Responses to
Stress


Tuesday, December 06 | 8:30AM - 11:45AM
Regulation of Stress Responses
Room: Eldorado B

Speaker 6 of 8
Peter D. Nagy, University of Kentucky, USA
A Small Plant Virus Co-opts Heat Shock Protein and the Actin Cytoskeleton and Rewires Glycolytic Pathway during Infection

Tuesday, December 06 | 8:30AM - 11:45AM
Regulation of Stress Responses
Room: Eldorado B

Speaker 7 of 8
Walid A. Houry, University of Toronto, Canada
Short Talk: Systematic Characterization of the Chaperone Networks Required for Cellular Protein Homeostasis

Tuesday, December 06 | 8:30AM - 11:45AM
Regulation of Stress Responses
Room: Eldorado B

Speaker 8 of 8
Sebastian Aguirre, Mount Sinai School of Medicine, USA
Short Talk: The DNA Sensor cGAS Detects Dengue Virus Infection Collateral Damage

Tuesday, December 06 | 11:45AM - 2:30PM
On Own for Lunch


Tuesday, December 06 | 11:45AM - 1:00PM
Poster Setup
Room: Anasazi Ballroom


Tuesday, December 06 | 1:00PM - 10:00PM
Poster Viewing
Room: Anasazi Ballroom


Tuesday, December 06 | 2:30PM - 4:30PM
Workshop 2: RNA Granules and Regulation of Translation
Room: Eldorado B

Speaker 1 of 7
* Paul J. Anderson, Harvard Medical School, USA

Tuesday, December 06 | 2:30PM - 4:30PM
Workshop 2: RNA Granules and Regulation of Translation
Room: Eldorado B

Speaker 2 of 7
Wei-Chih Tsai, Baylor College of Medicine, USA
Arginine Demethylation of G3BP1 Promotes Stress Granules Assembly

Tuesday, December 06 | 2:30PM - 4:30PM
Workshop 2: RNA Granules and Regulation of Translation
Room: Eldorado B

Speaker 3 of 7
Bruce W. Banfield, Queen's University, Canada
Herpes Simplex Virus Type 2 Promotes Stress Granule Disassembly Via the Endoribonuclease Activity of Virion Host Shutoff Protein

Tuesday, December 06 | 2:30PM - 4:30PM
Workshop 2: RNA Granules and Regulation of Translation
Room: Eldorado B

Speaker 4 of 7
Jason Mackenzie, University of Melbourne, Australia
Norovirus Translation: Control at the Stress Granule-PKR-p-elf2alpha Axis

Tuesday, December 06 | 2:30PM - 4:30PM
Workshop 2: RNA Granules and Regulation of Translation
Room: Eldorado B

Speaker 5 of 7
Huib Rabouw, Utrecht University, Netherlands
Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

Tuesday, December 06 | 2:30PM - 4:30PM
Workshop 2: RNA Granules and Regulation of Translation
Room: Eldorado B

Speaker 6 of 7
Ji-Young Youn, Lunefeld Tanenbaum Research Institute, Canada
Identification of Novel Protein Components of Stress Granules and Processing Bodies using BioID Approach

Tuesday, December 06 | 2:30PM - 4:30PM
Workshop 2: RNA Granules and Regulation of Translation
Room: Eldorado B

Speaker 7 of 7
Alessia Ruggieri, University of Heidelberg, Germany
Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses

Tuesday, December 06 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Tuesday, December 06 | 5:00PM - 7:00PM
Infectious Agents and Oxidative Stress
Room: Eldorado B

Speaker 1 of 5
* Robert H. Silverman, Cleveland Clinic Foundation, USA

Tuesday, December 06 | 5:00PM - 7:00PM
Infectious Agents and Oxidative Stress
Room: Eldorado B

Speaker 2 of 5
Sandra K. Weller, University of Connecticut School of Medicine, USA
Herpes Simplex Virus Manipulates Cellular Oxidative Stress Responses to Promote Lytic Infection

Tuesday, December 06 | 5:00PM - 7:00PM
Infectious Agents and Oxidative Stress
Room: Eldorado B

Speaker 3 of 5
Christopher F. Basler, Georgia State University, USA
Marburg Virus VP24 Protein Interacts with Keap1 to Engage the Antioxidant Response Pathway

Tuesday, December 06 | 5:00PM - 7:00PM
Infectious Agents and Oxidative Stress
Room: Eldorado B

Speaker 4 of 5
Margo A. Brinton, Georgia State University, USA
Resistance of Flavivirus-infected Cells to Arsenite-induced Stress Granule Formation is Mediated by Activation of the Cell Antioxidant Pathway.

Tuesday, December 06 | 5:00PM - 7:00PM
Infectious Agents and Oxidative Stress
Room: Eldorado B

Speaker 5 of 5
Eric Skaar, Vanderbilt University, USA
Short Talk: Dietary Manganese Supplementation Influences the Oxidative Stress Response to Staphylococcus Aureus during Infection of the Heart

Tuesday, December 06 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Anasazi Ballroom
No registration fees are used to fund alcohol served at this function.

Tuesday, December 06 | 7:30PM - 10:00PM
Poster Session 2
Room: Anasazi Ballroom


Wednesday, December 07 | 7:30AM - 8:30AM
Breakfast
Room: Anasazi Ballroom


Wednesday, December 07 | 8:30AM - 11:45AM
Autophagy and Host Defense Against Infectious Agents
Room: Eldorado B

Speaker 1 of 8
* Sara R. Cherry, University of Pennsylvania, USA

Wednesday, December 07 | 8:30AM - 11:45AM
Autophagy and Host Defense Against Infectious Agents
Room: Eldorado B

Speaker 2 of 8
Beth Levine, University of Texas Southwestern Medical Center, USA
Conserved Mechanisms for Autophagic Removal of Mitochondria and Microbes

Wednesday, December 07 | 8:30AM - 11:45AM
Autophagy and Host Defense Against Infectious Agents
Room: Eldorado B

Speaker 3 of 8
Herbert (Skip) W. Virgin, Vir Biotechnology, USA
Regulation of Tissue Inflammation by Autophagy Genes through Multiple Mechanisms

Wednesday, December 07 | 8:30AM - 11:45AM
Autophagy and Host Defense Against Infectious Agents
Room: Eldorado B


Coffee Break

Wednesday, December 07 | 8:30AM - 11:45AM
Autophagy and Host Defense Against Infectious Agents
Room: Eldorado B

Speaker 5 of 8
Felix Randow, Medical Research Council, UK
How Autophagy Defends the Cytosol Against Bacterial Invasion

Wednesday, December 07 | 8:30AM - 11:45AM
Autophagy and Host Defense Against Infectious Agents
Room: Eldorado B

Speaker 6 of 8
Jae U. Jung, Keck School of Medicine of University of Southern California, USA
Viral Manipulation of Autophagy for Viral Lifecycle

Wednesday, December 07 | 8:30AM - 11:45AM
Autophagy and Host Defense Against Infectious Agents
Room: Eldorado B

Speaker 7 of 8
Chiara Calabrese, University of Cologne, Germany
Short Talk: Salmonella Typhimurium Disrupts Sirt1/AMPK Signaling Network to Impair Autophagy

Wednesday, December 07 | 8:30AM - 11:45AM
Autophagy and Host Defense Against Infectious Agents
Room: Eldorado B

Speaker 8 of 8
Elena Muscolino, Heinrich Pette Institute, Germany
Short Talk: Murine Cytomegalovirus Recruits the Retromer Complex to Promote NEMO Degradation by Autophagy

Wednesday, December 07 | 11:45AM - 2:30PM
On Own for Lunch


Wednesday, December 07 | 11:45AM - 1:00PM
Poster Setup
Room: Anasazi Ballroom


Wednesday, December 07 | 1:00PM - 10:00PM
Poster Viewing
Room: Anasazi Ballroom


Wednesday, December 07 | 2:30PM - 4:30PM
Workshop 3: Autophagy, Regulation of Stress and Metabolic St
ress
Room: Eldorado B

Speaker 1 of 9
* Herbert (Skip) W. Virgin, Vir Biotechnology, USA

Wednesday, December 07 | 2:30PM - 4:30PM
Workshop 3: Autophagy, Regulation of Stress and Metabolic St
ress
Room: Eldorado B

Speaker 2 of 9
Jennifer Corcoran, Dalhousie University, Canada
Viral Control of Autophagy to Reprogram the Host Cell Secretome

Wednesday, December 07 | 2:30PM - 4:30PM
Workshop 3: Autophagy, Regulation of Stress and Metabolic St
ress
Room: Eldorado B

Speaker 3 of 9
Alexandra Boeske, Forschungszentrum Jülich, Germany
GABARAPs Mediate Anterograde Transport and Secretion of HIV-1 Nef via Mechanisms Related to Unconventional Protein Secretion

Wednesday, December 07 | 2:30PM - 4:30PM
Workshop 3: Autophagy, Regulation of Stress and Metabolic St
ress
Room: Eldorado B

Speaker 4 of 9
Nazira El-Hage, Florida International University, USA
Electro-Magnetic Nano-Particle Bound Beclin1 siRNA Crosses the Blood–Brain Barrier to Attenuate the Inflammatory Effects of HIV-1 Infection in vitro

Wednesday, December 07 | 2:30PM - 4:30PM
Workshop 3: Autophagy, Regulation of Stress and Metabolic St
ress
Room: Eldorado B

Speaker 5 of 9
Elizabeth Figueroa-Juárez, Instituto Nacional de Ciencias Médicas y Nutrición, S.Z., Mexico
Renal Endoplasmic Reticulum Stress and its Modulation by Resveratrol

Wednesday, December 07 | 2:30PM - 4:30PM
Workshop 3: Autophagy, Regulation of Stress and Metabolic St
ress
Room: Eldorado B

Speaker 6 of 9
Jessica Tsalikis, University of Toronto, Canada
The Role of U snRNA Maturation and mRNA Splicing Regulation in Response to Metabolic Stress and Bacterial Infection

Wednesday, December 07 | 2:30PM - 4:30PM
Workshop 3: Autophagy, Regulation of Stress and Metabolic St
ress
Room: Eldorado B

Speaker 7 of 9
Julien Moretti, Mount Sinai School of Medicine, USA
Vita-PAMP Sensing by STING Orchestrates Stress-Induced ER-phagy Apical to a Type-I Interferon Response

Wednesday, December 07 | 2:30PM - 4:30PM
Workshop 3: Autophagy, Regulation of Stress and Metabolic St
ress
Room: Eldorado B

Speaker 8 of 9
Teresa S. Wiley, Wiley Systems, Inc, USA
Autophagy Pathways and the Effects of Steroid Hormones

Wednesday, December 07 | 2:30PM - 4:30PM
Workshop 3: Autophagy, Regulation of Stress and Metabolic St
ress
Room: Eldorado B

Speaker 9 of 9
Angela M. Phillips, Massachusetts Institute of Technology, USA
Host Proteostasis Network-Mediated Modulation of Influenza Evolution

Wednesday, December 07 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Wednesday, December 07 | 5:00PM - 7:00PM
Intracellular Infectious Agents and Metabolic Stress
Room: Eldorado B

Speaker 1 of 5
* Craig McCormick, Dalhousie University, Canada

Wednesday, December 07 | 5:00PM - 7:00PM
Intracellular Infectious Agents and Metabolic Stress
Room: Eldorado B

Speaker 2 of 5
Joshua C. Munger, University of Rochester Medical Center, USA
Harnessing Small Molecule Stress Pathways to Support Viral Infection

Wednesday, December 07 | 5:00PM - 7:00PM
Intracellular Infectious Agents and Metabolic Stress
Room: Eldorado B

Speaker 3 of 5
Stephen E. Girardin, University of Toronto, Canada
A Cytosolic Unfolded Protein Response Controls Innate Immune Signaling

Wednesday, December 07 | 5:00PM - 7:00PM
Intracellular Infectious Agents and Metabolic Stress
Room: Eldorado B

Speaker 4 of 5
James C. Alwine, University of Pennsylvania School of Medicine, USA
The Masterful Manipulation of Host Cell Stress Responses, Signaling and Metabolism by Human Cytomegalovirus

Wednesday, December 07 | 5:00PM - 7:00PM
Intracellular Infectious Agents and Metabolic Stress
Room: Eldorado B

Speaker 5 of 5
Andrew Timmons, Johns Hopkins Hospital, USA
Short Talk: Small Molecule Inhibition of Intrinsic Stress Pathways Substantially Reduces HIV Transcription upon T Cell Activation

Wednesday, December 07 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Anasazi Ballroom
No registration fees are used to fund alcohol served at this function.

Wednesday, December 07 | 7:30PM - 10:00PM
Poster Session 3
Room: Anasazi Ballroom


Thursday, December 08 | 7:30AM - 8:30AM
Breakfast
Room: Anasazi Ballroom


Thursday, December 08 | 8:30AM - 11:45AM
Integrated Stress Responses and Infectious Agents
Room: Eldorado B

Speaker 1 of 7
Sara R. Cherry, University of Pennsylvania, USA
Systems Approaches to Study Antiviral Immunity

Thursday, December 08 | 8:30AM - 11:45AM
Integrated Stress Responses and Infectious Agents
Room: Eldorado B

Speaker 2 of 7
George A. Belov, University of Maryland, USA
Membrane Metabolism of Picornavirus-Infected Cells: A Little Virus Makes A Big Mess

Thursday, December 08 | 8:30AM - 11:45AM
Integrated Stress Responses and Infectious Agents
Room: Eldorado B


Coffee Break

Thursday, December 08 | 8:30AM - 11:45AM
Integrated Stress Responses and Infectious Agents
Room: Eldorado B

Speaker 4 of 7
Denise A. Galloway, Fred Hutchinson Cancer Research Center, USA
Human Papillomaviruses dampen the Response to DNA Damage

Thursday, December 08 | 8:30AM - 11:45AM
Integrated Stress Responses and Infectious Agents
Room: Eldorado B

Speaker 5 of 7
* Ralph Isberg, Tufts University School of Medicine, USA
Bacterial Community Behavior in Deep Tissue Sites during Microbial Disease

Thursday, December 08 | 8:30AM - 11:45AM
Integrated Stress Responses and Infectious Agents
Room: Eldorado B

Speaker 6 of 7
Scott Espenschied, Duke University, USA
Short Talk: In vivo Analysis of Intestinal Epithelial Damage Responses in a Zebrafish Model of NSAID-Induced Enteropathy

Thursday, December 08 | 8:30AM - 11:45AM
Integrated Stress Responses and Infectious Agents
Room: Eldorado B

Speaker 7 of 7
Adam R. Renslo, University of California, San Francisco, USA
Short Talk: Discovery and Optimization of Small Molecule Antagonists of the Integrated Stress Response

Thursday, December 08 | 11:45AM - 2:30PM
On Own for Lunch


Thursday, December 08 | 2:30PM - 4:30PM
Workshop 4: Integrated Stress Responses and the DNA Damage R
esponse
Room: Eldorado B

Speaker 1 of 8
* Denise A. Galloway, Fred Hutchinson Cancer Research Center, USA

Thursday, December 08 | 2:30PM - 4:30PM
Workshop 4: Integrated Stress Responses and the DNA Damage R
esponse
Room: Eldorado B

Speaker 2 of 8
Wolfram Brune, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Germany
Activation and Inhibition of Caspase-2 by Human Cytomegalovirus

Thursday, December 08 | 2:30PM - 4:30PM
Workshop 4: Integrated Stress Responses and the DNA Damage R
esponse
Room: Eldorado B

Speaker 3 of 8
Christopher Fisher, University of Florida College of Medicine, USA
HSV-1 Infection Activates ATR and Chk1, Mislocalizes the Phosphorylated Proteins, and Utilizes their Activity to Promote Viral Replication

Thursday, December 08 | 2:30PM - 4:30PM
Workshop 4: Integrated Stress Responses and the DNA Damage R
esponse
Room: Eldorado B

Speaker 4 of 8
Terri Edwards, University of Florida, USA
Rebound of Human Papillomavirus (Hpv) Dna Episomes Following Antiviral Treatment Shares Fundamental Features with Genome Amplification During the HPV Life Cycle

Thursday, December 08 | 2:30PM - 4:30PM
Workshop 4: Integrated Stress Responses and the DNA Damage R
esponse
Room: Eldorado B

Speaker 5 of 8
Priya Luthra, Georgia State University, USA
The Crosstalk Between DNA Damage and Innate Immune Responses Circumvents Ebola Virus Immune Evasion Mechanisms

Thursday, December 08 | 2:30PM - 4:30PM
Workshop 4: Integrated Stress Responses and the DNA Damage R
esponse
Room: Eldorado B

Speaker 6 of 8
Michael P. Sheetz, Mechanobiology Institute, National University of Singapore, Singapore
DNA Damage Causes Rapid Accumulation of Phosphoinositides to Recruit ATR but not ATM

Thursday, December 08 | 2:30PM - 4:30PM
Workshop 4: Integrated Stress Responses and the DNA Damage R
esponse
Room: Eldorado B

Speaker 7 of 8
Rong Tan, University of Pittsburgh, USA
Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1

Thursday, December 08 | 2:30PM - 4:30PM
Workshop 4: Integrated Stress Responses and the DNA Damage R
esponse
Room: Eldorado B

Speaker 8 of 8
Alexander Zaika, Vanderbilt University Medical Center, USA
Bacterial Pathogen Helicobacter Pylori Modulates Cellular Responses to DNA Damage and Oncogenic Stress by Inducing Degradation of p53 Protein and Altering Expression of p53 Isoforms

Thursday, December 08 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Thursday, December 08 | 5:00PM - 6:45PM
Infectious Agents and the DNA Damage Response
Room: Eldorado B

Speaker 1 of 4
* Sandra K. Weller, University of Connecticut School of Medicine, USA

Thursday, December 08 | 5:00PM - 6:45PM
Infectious Agents and the DNA Damage Response
Room: Eldorado B

Speaker 2 of 4
Matthew D. Weitzman, Children's Hospital of Philadelphia, USA
DNA Damage Responses to DNA Virus Infection

Thursday, December 08 | 5:00PM - 6:45PM
Infectious Agents and the DNA Damage Response
Room: Eldorado B

Speaker 3 of 4
Richard I. Morimoto, Northwestern University, USA
Regulation of the Heat Shock Response and Proteostasis Networks

Thursday, December 08 | 5:00PM - 6:45PM
Infectious Agents and the DNA Damage Response
Room: Eldorado B

Speaker 4 of 4
Hugues de Thé, Hopital St. Louis, France
In vivo Sumoylation Control by PML Nuclear Bodies under Oxidative Stress

Thursday, December 08 | 6:45PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Eldorado B


Thursday, December 08 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Anasazi Ballroom
No registration fees are used to fund alcohol served at this function.

Thursday, December 08 | 8:00PM - 11:00PM
Entertainment
Room: Anasazi Ballroom
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, December 08 | 8:00PM - 11:00PM
Cash Bar
Room: Anasazi Ballroom


Friday, December 09 | 10:25AM - 10:25AM
Departure


*Session Chair.