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Web Desc
Cellular Stress Responses and Infectious Agents Organizer(s): Margo A. Brinton, Sandra K. Weller and Beth Levine Date: December 04 - 08, 2016 Location: Eldorado Hotel & Spa, Santa Fe, NM, USA Supported by the Directors' Fund Summary of Meeting: This conference will bring together cell biologists studying various cellular stress responses and researchers interested in how various infectious agents activate and manipulate host cellular stress responses. Examples of cellular stress responses activated by infectious agents are: the stress granule response, the unfolded protein response, the DNA damage response, responses to oxidative stress and metabolic stress, autophagy, and other protein quality control responses. Many of these cellular homeostatic mechanisms function as part of innate and intrinsic defense mechanisms to counteract infections. Various infectious agents have evolved to subvert and manipulate many of these anti-pathogen mechanisms by utilizing, evading or inactivating components of these cellular pathways. The study of interactions between infectious agents and these pathways provides new insights about cellular stress responses and identifies new targets for the development of novel therapies for the treatment of infectious diseases. Scholarship Deadline: August 4 2016 Discounted Abstract Deadline: August 4 2016 Abstract Deadline: September 12 2016 Discounted Registration Deadline: October 4 2016 We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI126782-01 Funding for this conference was made possible (in part) by 1R13AI126782-01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Cellular Stress Responses and Infectious Agents

Organizer(s): Margo A. Brinton, Sandra K. Weller and Beth Levine

Date: December 04 - 08, 2016
Location: Eldorado Hotel & Spa, Santa Fe, NM, USA

Supported by the Directors' Fund

Summary of Meeting:

This conference will bring together cell biologists studying various cellular stress responses and researchers interested in how various infectious agents activate and manipulate host cellular stress responses. Examples of cellular stress responses activated by infectious agents are: the stress granule response, the unfolded protein response, the DNA damage response, responses to oxidative stress and metabolic stress, autophagy, and other protein quality control responses. Many of these cellular homeostatic mechanisms function as part of innate and intrinsic defense mechanisms to counteract infections. Various infectious agents have evolved to subvert and manipulate many of these anti-pathogen mechanisms by utilizing, evading or inactivating components of these cellular pathways. The study of interactions between infectious agents and these pathways provides new insights about cellular stress responses and identifies new targets for the development of novel therapies for the treatment of infectious diseases.

Scholarship Deadline: August 4 2016

Discounted Abstract Deadline: August 4 2016

Abstract Deadline: September 12 2016

Discounted Registration Deadline: October 4 2016

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI126782-01
Funding for this conference was made possible (in part) by 1R13AI126782-01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, December 04 \| 4:00PM - 8:00PM Arrival and Registration Room: Eldorado Lounge
Sunday, December 04 \| 6:00PM - 8:00PM Welcome Mixer Room: Eldorado Lounge No registration fees are used to fund alcohol served at this function.
Monday, December 05 \| 7:30AM - 8:30AM Breakfast Room: Anasazi Ballroom
Monday, December 05 \| 8:30AM - 9:30AM Welcome and Keynote Address Room: Eldorado B Speaker 1 of 3 * Margo A. Brinton, Georgia State University, USA
Monday, December 05 \| 8:30AM - 9:30AM Welcome and Keynote Address Room: Eldorado B Speaker 2 of 3 * Beth Levine, University of Texas Southwestern Medical Center, USA
Monday, December 05 \| 8:30AM - 9:30AM Welcome and Keynote Address Room: Eldorado B Speaker 3 of 3 David Ron, University of Cambridge, UK Protein-Folding Homeostasis in the Endoplasmic Reticulum – Some Lessons from Microbes
Monday, December 05 \| 9:30AM - 12:00PM Unfolded Protein Response Room: Eldorado B Speaker 1 of 7 * Beth Levine, University of Texas Southwestern Medical Center, USA
Monday, December 05 \| 9:30AM - 12:00PM Unfolded Protein Response Room: Eldorado B Speaker 2 of 7 R. Luke Wiseman, The Scripps Research Institute, USA Regulating Secretory Proteostasis through the Unfolded Protein Response
Monday, December 05 \| 9:30AM - 12:00PM Unfolded Protein Response Room: Eldorado B Coffee Break
Monday, December 05 \| 9:30AM - 12:00PM Unfolded Protein Response Room: Eldorado B Speaker 4 of 7 Timothy A.J. Haystead, Duke University, USA Hsp90 Promotes HIV and Chikungunya Virus Replication, Hsp90 Inhibitors are Antiviral
Monday, December 05 \| 9:30AM - 12:00PM Unfolded Protein Response Room: Eldorado B Speaker 5 of 7 Claudio Soto, University of Texas Medical School at Houston, USA The Unfolded Protein Response after Prion Infection
Monday, December 05 \| 9:30AM - 12:00PM Unfolded Protein Response Room: Eldorado B Speaker 6 of 7 Timothy E. Audas, Simon Fraser University, Canada Short Talk: Adaptation to Stressors by Systemic Protein Amyloidogenesis
Monday, December 05 \| 9:30AM - 12:00PM Unfolded Protein Response Room: Eldorado B Speaker 7 of 7 Ross Buchan, University of Arizona, USA Short Talk: Endocytosis is a Key Regulator of TDP-43 Aggregation, Toxicity and Turnover
Monday, December 05 \| 12:00PM - 2:30PM On Own for Lunch
Monday, December 05 \| 12:00PM - 1:00PM Poster Setup Room: Anasazi Ballroom
Monday, December 05 \| 1:00PM - 10:00PM Poster Viewing Room: Anasazi Ballroom
Monday, December 05 \| 2:30PM - 4:30PM Workshop 1: Unfolded Protein Response and ER Stress Room: Eldorado B Speaker 1 of 7 * Timothy A.J. Haystead, Duke University, USA
Monday, December 05 \| 2:30PM - 4:30PM Workshop 1: Unfolded Protein Response and ER Stress Room: Eldorado B Speaker 2 of 7 Mitali Adlakha, University of Connecticut Health Center, USA HSV-1 Immediate Early Proteins ICP0 and ICP22 Manipulate the Cellular Protein Homeostatic Machinery
Monday, December 05 \| 2:30PM - 4:30PM Workshop 1: Unfolded Protein Response and ER Stress Room: Eldorado B Speaker 3 of 7 Vikas Anathy, University of Vermont, Larner College of Medicine, USA Activation of UPR Transducer ATF6alpha and Increases in PDIA3 is Required for Influenza Propagation and Development of Lung Pathology
Monday, December 05 \| 2:30PM - 4:30PM Workshop 1: Unfolded Protein Response and ER Stress Room: Eldorado B Speaker 4 of 7 Ben P. Johnston, Dalhousie University, Canada KSHV Modulates the IRE1-XBP1 Axis of the Unfolded Protein Response during Lytic Replication
Monday, December 05 \| 2:30PM - 4:30PM Workshop 1: Unfolded Protein Response and ER Stress Room: Eldorado B Speaker 5 of 7 Kimberly Kline, Nanyang Technological University, Singapore Streptolysin-Induced Endoplasmic Reticulum Stress Controls in vivo Biofilm Formation by Group A Streptococcus
Monday, December 05 \| 2:30PM - 4:30PM Workshop 1: Unfolded Protein Response and ER Stress Room: Eldorado B Speaker 6 of 7 Charles Grose, University of Iowa, USA Cellular Stress, Autophagosomes, Amphisomes and Virus Trafficking during Varicella Infection
Monday, December 05 \| 2:30PM - 4:30PM Workshop 1: Unfolded Protein Response and ER Stress Room: Eldorado B Speaker 7 of 7 Abagail Rosen, University of Virginia, USA A Novel, IRE1-Dependent Role for Sigma-1 Receptor in Control of Inflammatory Cytokine Production
Monday, December 05 \| 4:30PM - 5:00PM Coffee Available Room: Concourse
Monday, December 05 \| 5:00PM - 7:00PM Stress Granule Response, Modulation of Translation and Innat e Immunity Room: Eldorado B Speaker 1 of 5 * Margo A. Brinton, Georgia State University, USA
Monday, December 05 \| 5:00PM - 7:00PM Stress Granule Response, Modulation of Translation and Innat e Immunity Room: Eldorado B Speaker 2 of 5 Paul J. Anderson, Harvard Medical School, USA Stress Granules: RNA-centric Signaling Hubs
Monday, December 05 \| 5:00PM - 7:00PM Stress Granule Response, Modulation of Translation and Innat e Immunity Room: Eldorado B Speaker 3 of 5 Richard E. Lloyd, Baylor College of Medicine, USA Cross-Talk between RNA Granules and Innate Immunity
Monday, December 05 \| 5:00PM - 7:00PM Stress Granule Response, Modulation of Translation and Innat e Immunity Room: Eldorado B Speaker 4 of 5 Craig McCormick, Dalhousie University, Canada Control of Protein Synthesis in Influenza Virus-Infected Cells
Monday, December 05 \| 5:00PM - 7:00PM Stress Granule Response, Modulation of Translation and Innat e Immunity Room: Eldorado B Speaker 5 of 5 Mena Abdel-Nour, University of Toronto, Canada Short Talk: The eIF2 alpha Kinase HRI Senses Protein Aggregation and Facilitates Signaling of Cytosolic Innate Immune Receptors
Monday, December 05 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Anasazi Ballroom No registration fees are used to fund alcohol served at this function.
Monday, December 05 \| 7:30PM - 10:00PM Poster Session 1 Room: Anasazi Ballroom
Tuesday, December 06 \| 7:30AM - 8:30AM Breakfast Room: Anasazi Ballroom
Tuesday, December 06 \| 8:30AM - 11:45AM Regulation of Stress Responses Room: Eldorado B Speaker 1 of 8 * James C. Alwine, University of Pennsylvania School of Medicine, USA
Tuesday, December 06 \| 8:30AM - 11:45AM Regulation of Stress Responses Room: Eldorado B Speaker 2 of 8 Carolyn-Ann Robinson, Dalhousie University, Canada Activation of LXRalpha Inhibits Kaposi’s Sarcoma-Associated Herpesvirus Replication
Tuesday, December 06 \| 8:30AM - 11:45AM Regulation of Stress Responses Room: Eldorado B Speaker 3 of 8 Carmen Rivas, Centro Nacional de Biotecnología, Spain Regulation of Stress Responses by SUMOylation
Tuesday, December 06 \| 8:30AM - 11:45AM Regulation of Stress Responses Room: Eldorado B Coffee Break
Tuesday, December 06 \| 8:30AM - 11:45AM Regulation of Stress Responses Room: Eldorado B Speaker 5 of 8 Robert H. Silverman, Cleveland Clinic Foundation, USA The Role of 2’,5’-Oligoadenylate Synthetases in Cellular Responses to Stress
Tuesday, December 06 \| 8:30AM - 11:45AM Regulation of Stress Responses Room: Eldorado B Speaker 6 of 8 Peter D. Nagy, University of Kentucky, USA A Small Plant Virus Co-opts Heat Shock Protein and the Actin Cytoskeleton and Rewires Glycolytic Pathway during Infection
Tuesday, December 06 \| 8:30AM - 11:45AM Regulation of Stress Responses Room: Eldorado B Speaker 7 of 8 Walid A. Houry, University of Toronto, Canada Short Talk: Systematic Characterization of the Chaperone Networks Required for Cellular Protein Homeostasis
Tuesday, December 06 \| 8:30AM - 11:45AM Regulation of Stress Responses Room: Eldorado B Speaker 8 of 8 Sebastian Aguirre, Mount Sinai School of Medicine, USA Short Talk: The DNA Sensor cGAS Detects Dengue Virus Infection Collateral Damage
Tuesday, December 06 \| 11:45AM - 2:30PM On Own for Lunch
Tuesday, December 06 \| 11:45AM - 1:00PM Poster Setup Room: Anasazi Ballroom
Tuesday, December 06 \| 1:00PM - 10:00PM Poster Viewing Room: Anasazi Ballroom
Tuesday, December 06 \| 2:30PM - 4:30PM Workshop 2: RNA Granules and Regulation of Translation Room: Eldorado B Speaker 1 of 7 * Paul J. Anderson, Harvard Medical School, USA
Tuesday, December 06 \| 2:30PM - 4:30PM Workshop 2: RNA Granules and Regulation of Translation Room: Eldorado B Speaker 2 of 7 Wei-Chih Tsai, Baylor College of Medicine, USA Arginine Demethylation of G3BP1 Promotes Stress Granules Assembly
Tuesday, December 06 \| 2:30PM - 4:30PM Workshop 2: RNA Granules and Regulation of Translation Room: Eldorado B Speaker 3 of 7 Bruce W. Banfield, Queen's University, Canada Herpes Simplex Virus Type 2 Promotes Stress Granule Disassembly Via the Endoribonuclease Activity of Virion Host Shutoff Protein
Tuesday, December 06 \| 2:30PM - 4:30PM Workshop 2: RNA Granules and Regulation of Translation Room: Eldorado B Speaker 4 of 7 Jason Mackenzie, University of Melbourne, Australia Norovirus Translation: Control at the Stress Granule-PKR-p-elf2alpha Axis
Tuesday, December 06 \| 2:30PM - 4:30PM Workshop 2: RNA Granules and Regulation of Translation Room: Eldorado B Speaker 5 of 7 Huib Rabouw, Utrecht University, Netherlands Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses
Tuesday, December 06 \| 2:30PM - 4:30PM Workshop 2: RNA Granules and Regulation of Translation Room: Eldorado B Speaker 6 of 7 Ji-Young Youn, Lunefeld Tanenbaum Research Institute, Canada Identification of Novel Protein Components of Stress Granules and Processing Bodies using BioID Approach
Tuesday, December 06 \| 2:30PM - 4:30PM Workshop 2: RNA Granules and Regulation of Translation Room: Eldorado B Speaker 7 of 7 Alessia Ruggieri, University of Heidelberg, Germany Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses
Tuesday, December 06 \| 4:30PM - 5:00PM Coffee Available Room: Concourse
Tuesday, December 06 \| 5:00PM - 7:00PM Infectious Agents and Oxidative Stress Room: Eldorado B Speaker 1 of 5 * Robert H. Silverman, Cleveland Clinic Foundation, USA
Tuesday, December 06 \| 5:00PM - 7:00PM Infectious Agents and Oxidative Stress Room: Eldorado B Speaker 2 of 5 Sandra K. Weller, University of Connecticut School of Medicine, USA Herpes Simplex Virus Manipulates Cellular Oxidative Stress Responses to Promote Lytic Infection
Tuesday, December 06 \| 5:00PM - 7:00PM Infectious Agents and Oxidative Stress Room: Eldorado B Speaker 3 of 5 Christopher F. Basler, Georgia State University, USA Marburg Virus VP24 Protein Interacts with Keap1 to Engage the Antioxidant Response Pathway
Tuesday, December 06 \| 5:00PM - 7:00PM Infectious Agents and Oxidative Stress Room: Eldorado B Speaker 4 of 5 Margo A. Brinton, Georgia State University, USA Resistance of Flavivirus-infected Cells to Arsenite-induced Stress Granule Formation is Mediated by Activation of the Cell Antioxidant Pathway.
Tuesday, December 06 \| 5:00PM - 7:00PM Infectious Agents and Oxidative Stress Room: Eldorado B Speaker 5 of 5 Eric Skaar, Vanderbilt University, USA Short Talk: Dietary Manganese Supplementation Influences the Oxidative Stress Response to Staphylococcus Aureus during Infection of the Heart
Tuesday, December 06 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Anasazi Ballroom No registration fees are used to fund alcohol served at this function.
Tuesday, December 06 \| 7:30PM - 10:00PM Poster Session 2 Room: Anasazi Ballroom
Wednesday, December 07 \| 7:30AM - 8:30AM Breakfast Room: Anasazi Ballroom
Wednesday, December 07 \| 8:30AM - 11:45AM Autophagy and Host Defense Against Infectious Agents Room: Eldorado B Speaker 1 of 8 * Sara R. Cherry, University of Pennsylvania, USA
Wednesday, December 07 \| 8:30AM - 11:45AM Autophagy and Host Defense Against Infectious Agents Room: Eldorado B Speaker 2 of 8 Beth Levine, University of Texas Southwestern Medical Center, USA Conserved Mechanisms for Autophagic Removal of Mitochondria and Microbes
Wednesday, December 07 \| 8:30AM - 11:45AM Autophagy and Host Defense Against Infectious Agents Room: Eldorado B Speaker 3 of 8 Herbert (Skip) W. Virgin, Vir Biotechnology, USA Regulation of Tissue Inflammation by Autophagy Genes through Multiple Mechanisms
Wednesday, December 07 \| 8:30AM - 11:45AM Autophagy and Host Defense Against Infectious Agents Room: Eldorado B Coffee Break
Wednesday, December 07 \| 8:30AM - 11:45AM Autophagy and Host Defense Against Infectious Agents Room: Eldorado B Speaker 5 of 8 Felix Randow, Medical Research Council, UK How Autophagy Defends the Cytosol Against Bacterial Invasion
Wednesday, December 07 \| 8:30AM - 11:45AM Autophagy and Host Defense Against Infectious Agents Room: Eldorado B Speaker 6 of 8 Jae U. Jung, Keck School of Medicine of University of Southern California, USA Viral Manipulation of Autophagy for Viral Lifecycle
Wednesday, December 07 \| 8:30AM - 11:45AM Autophagy and Host Defense Against Infectious Agents Room: Eldorado B Speaker 7 of 8 Chiara Calabrese, University of Cologne, Germany Short Talk: Salmonella Typhimurium Disrupts Sirt1/AMPK Signaling Network to Impair Autophagy
Wednesday, December 07 \| 8:30AM - 11:45AM Autophagy and Host Defense Against Infectious Agents Room: Eldorado B Speaker 8 of 8 Elena Muscolino, Heinrich Pette Institute, Germany Short Talk: Murine Cytomegalovirus Recruits the Retromer Complex to Promote NEMO Degradation by Autophagy
Wednesday, December 07 \| 11:45AM - 2:30PM On Own for Lunch
Wednesday, December 07 \| 11:45AM - 1:00PM Poster Setup Room: Anasazi Ballroom
Wednesday, December 07 \| 1:00PM - 10:00PM Poster Viewing Room: Anasazi Ballroom
Wednesday, December 07 \| 2:30PM - 4:30PM Workshop 3: Autophagy, Regulation of Stress and Metabolic St ress Room: Eldorado B Speaker 1 of 9 * Herbert (Skip) W. Virgin, Vir Biotechnology, USA
Wednesday, December 07 \| 2:30PM - 4:30PM Workshop 3: Autophagy, Regulation of Stress and Metabolic St ress Room: Eldorado B Speaker 2 of 9 Jennifer Corcoran, Dalhousie University, Canada Viral Control of Autophagy to Reprogram the Host Cell Secretome
Wednesday, December 07 \| 2:30PM - 4:30PM Workshop 3: Autophagy, Regulation of Stress and Metabolic St ress Room: Eldorado B Speaker 3 of 9 Alexandra Boeske, Forschungszentrum Jülich, Germany GABARAPs Mediate Anterograde Transport and Secretion of HIV-1 Nef via Mechanisms Related to Unconventional Protein Secretion
Wednesday, December 07 \| 2:30PM - 4:30PM Workshop 3: Autophagy, Regulation of Stress and Metabolic St ress Room: Eldorado B Speaker 4 of 9 Nazira El-Hage, Florida International University, USA Electro-Magnetic Nano-Particle Bound Beclin1 siRNA Crosses the Blood–Brain Barrier to Attenuate the Inflammatory Effects of HIV-1 Infection in vitro
Wednesday, December 07 \| 2:30PM - 4:30PM Workshop 3: Autophagy, Regulation of Stress and Metabolic St ress Room: Eldorado B Speaker 5 of 9 Elizabeth Figueroa-Juárez, Instituto Nacional de Ciencias Médicas y Nutrición, S.Z., Mexico Renal Endoplasmic Reticulum Stress and its Modulation by Resveratrol
Wednesday, December 07 \| 2:30PM - 4:30PM Workshop 3: Autophagy, Regulation of Stress and Metabolic St ress Room: Eldorado B Speaker 6 of 9 Jessica Tsalikis, University of Toronto, Canada The Role of U snRNA Maturation and mRNA Splicing Regulation in Response to Metabolic Stress and Bacterial Infection
Wednesday, December 07 \| 2:30PM - 4:30PM Workshop 3: Autophagy, Regulation of Stress and Metabolic St ress Room: Eldorado B Speaker 7 of 9 Julien Moretti, Mount Sinai School of Medicine, USA Vita-PAMP Sensing by STING Orchestrates Stress-Induced ER-phagy Apical to a Type-I Interferon Response
Wednesday, December 07 \| 2:30PM - 4:30PM Workshop 3: Autophagy, Regulation of Stress and Metabolic St ress Room: Eldorado B Speaker 8 of 9 Teresa S. Wiley, Wiley Systems, Inc, USA Autophagy Pathways and the Effects of Steroid Hormones
Wednesday, December 07 \| 2:30PM - 4:30PM Workshop 3: Autophagy, Regulation of Stress and Metabolic St ress Room: Eldorado B Speaker 9 of 9 Angela M. Phillips, Massachusetts Institute of Technology, USA Host Proteostasis Network-Mediated Modulation of Influenza Evolution
Wednesday, December 07 \| 4:30PM - 5:00PM Coffee Available Room: Concourse
Wednesday, December 07 \| 5:00PM - 7:00PM Intracellular Infectious Agents and Metabolic Stress Room: Eldorado B Speaker 1 of 5 * Craig McCormick, Dalhousie University, Canada
Wednesday, December 07 \| 5:00PM - 7:00PM Intracellular Infectious Agents and Metabolic Stress Room: Eldorado B Speaker 2 of 5 Joshua C. Munger, University of Rochester Medical Center, USA Harnessing Small Molecule Stress Pathways to Support Viral Infection
Wednesday, December 07 \| 5:00PM - 7:00PM Intracellular Infectious Agents and Metabolic Stress Room: Eldorado B Speaker 3 of 5 Stephen E. Girardin, University of Toronto, Canada A Cytosolic Unfolded Protein Response Controls Innate Immune Signaling
Wednesday, December 07 \| 5:00PM - 7:00PM Intracellular Infectious Agents and Metabolic Stress Room: Eldorado B Speaker 4 of 5 James C. Alwine, University of Pennsylvania School of Medicine, USA The Masterful Manipulation of Host Cell Stress Responses, Signaling and Metabolism by Human Cytomegalovirus
Wednesday, December 07 \| 5:00PM - 7:00PM Intracellular Infectious Agents and Metabolic Stress Room: Eldorado B Speaker 5 of 5 Andrew Timmons, Johns Hopkins Hospital, USA Short Talk: Small Molecule Inhibition of Intrinsic Stress Pathways Substantially Reduces HIV Transcription upon T Cell Activation
Wednesday, December 07 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Anasazi Ballroom No registration fees are used to fund alcohol served at this function.
Wednesday, December 07 \| 7:30PM - 10:00PM Poster Session 3 Room: Anasazi Ballroom
Thursday, December 08 \| 7:30AM - 8:30AM Breakfast Room: Anasazi Ballroom
Thursday, December 08 \| 8:30AM - 11:45AM Integrated Stress Responses and Infectious Agents Room: Eldorado B Speaker 1 of 7 Sara R. Cherry, University of Pennsylvania, USA Systems Approaches to Study Antiviral Immunity
Thursday, December 08 \| 8:30AM - 11:45AM Integrated Stress Responses and Infectious Agents Room: Eldorado B Speaker 2 of 7 George A. Belov, University of Maryland, USA Membrane Metabolism of Picornavirus-Infected Cells: A Little Virus Makes A Big Mess
Thursday, December 08 \| 8:30AM - 11:45AM Integrated Stress Responses and Infectious Agents Room: Eldorado B Coffee Break
Thursday, December 08 \| 8:30AM - 11:45AM Integrated Stress Responses and Infectious Agents Room: Eldorado B Speaker 4 of 7 Denise A. Galloway, Fred Hutchinson Cancer Research Center, USA Human Papillomaviruses dampen the Response to DNA Damage
Thursday, December 08 \| 8:30AM - 11:45AM Integrated Stress Responses and Infectious Agents Room: Eldorado B Speaker 5 of 7 * Ralph Isberg, Tufts University School of Medicine, USA Bacterial Community Behavior in Deep Tissue Sites during Microbial Disease
Thursday, December 08 \| 8:30AM - 11:45AM Integrated Stress Responses and Infectious Agents Room: Eldorado B Speaker 6 of 7 Scott Espenschied, Duke University, USA Short Talk: In vivo Analysis of Intestinal Epithelial Damage Responses in a Zebrafish Model of NSAID-Induced Enteropathy
Thursday, December 08 \| 8:30AM - 11:45AM Integrated Stress Responses and Infectious Agents Room: Eldorado B Speaker 7 of 7 Adam R. Renslo, University of California, San Francisco, USA Short Talk: Discovery and Optimization of Small Molecule Antagonists of the Integrated Stress Response
Thursday, December 08 \| 11:45AM - 2:30PM On Own for Lunch
Thursday, December 08 \| 2:30PM - 4:30PM Workshop 4: Integrated Stress Responses and the DNA Damage R esponse Room: Eldorado B Speaker 1 of 8 * Denise A. Galloway, Fred Hutchinson Cancer Research Center, USA
Thursday, December 08 \| 2:30PM - 4:30PM Workshop 4: Integrated Stress Responses and the DNA Damage R esponse Room: Eldorado B Speaker 2 of 8 Wolfram Brune, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Germany Activation and Inhibition of Caspase-2 by Human Cytomegalovirus
Thursday, December 08 \| 2:30PM - 4:30PM Workshop 4: Integrated Stress Responses and the DNA Damage R esponse Room: Eldorado B Speaker 3 of 8 Christopher Fisher, University of Florida College of Medicine, USA HSV-1 Infection Activates ATR and Chk1, Mislocalizes the Phosphorylated Proteins, and Utilizes their Activity to Promote Viral Replication
Thursday, December 08 \| 2:30PM - 4:30PM Workshop 4: Integrated Stress Responses and the DNA Damage R esponse Room: Eldorado B Speaker 4 of 8 Terri Edwards, University of Florida, USA Rebound of Human Papillomavirus (Hpv) Dna Episomes Following Antiviral Treatment Shares Fundamental Features with Genome Amplification During the HPV Life Cycle
Thursday, December 08 \| 2:30PM - 4:30PM Workshop 4: Integrated Stress Responses and the DNA Damage R esponse Room: Eldorado B Speaker 5 of 8 Priya Luthra, Georgia State University, USA The Crosstalk Between DNA Damage and Innate Immune Responses Circumvents Ebola Virus Immune Evasion Mechanisms
Thursday, December 08 \| 2:30PM - 4:30PM Workshop 4: Integrated Stress Responses and the DNA Damage R esponse Room: Eldorado B Speaker 6 of 8 Michael P. Sheetz, Mechanobiology Institute, National University of Singapore, Singapore DNA Damage Causes Rapid Accumulation of Phosphoinositides to Recruit ATR but not ATM
Thursday, December 08 \| 2:30PM - 4:30PM Workshop 4: Integrated Stress Responses and the DNA Damage R esponse Room: Eldorado B Speaker 7 of 8 Rong Tan, University of Pittsburgh, USA Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1
Thursday, December 08 \| 2:30PM - 4:30PM Workshop 4: Integrated Stress Responses and the DNA Damage R esponse Room: Eldorado B Speaker 8 of 8 Alexander Zaika, Vanderbilt University Medical Center, USA Bacterial Pathogen Helicobacter Pylori Modulates Cellular Responses to DNA Damage and Oncogenic Stress by Inducing Degradation of p53 Protein and Altering Expression of p53 Isoforms
Thursday, December 08 \| 4:30PM - 5:00PM Coffee Available Room: Concourse
Thursday, December 08 \| 5:00PM - 6:45PM Infectious Agents and the DNA Damage Response Room: Eldorado B Speaker 1 of 4 * Sandra K. Weller, University of Connecticut School of Medicine, USA
Thursday, December 08 \| 5:00PM - 6:45PM Infectious Agents and the DNA Damage Response Room: Eldorado B Speaker 2 of 4 Matthew D. Weitzman, Children's Hospital of Philadelphia, USA DNA Damage Responses to DNA Virus Infection
Thursday, December 08 \| 5:00PM - 6:45PM Infectious Agents and the DNA Damage Response Room: Eldorado B Speaker 3 of 4 Richard I. Morimoto, Northwestern University, USA Regulation of the Heat Shock Response and Proteostasis Networks
Thursday, December 08 \| 5:00PM - 6:45PM Infectious Agents and the DNA Damage Response Room: Eldorado B Speaker 4 of 4 Hugues de Thé, Hopital St. Louis, France In vivo Sumoylation Control by PML Nuclear Bodies under Oxidative Stress
Thursday, December 08 \| 6:45PM - 7:15PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Room: Eldorado B
Thursday, December 08 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Anasazi Ballroom No registration fees are used to fund alcohol served at this function.
Thursday, December 08 \| 8:00PM - 11:00PM Entertainment Room: Anasazi Ballroom Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
Thursday, December 08 \| 8:00PM - 11:00PM Cash Bar Room: Anasazi Ballroom
Friday, December 09 \| 10:25AM - 10:25AM Departure *Session Chair.