Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Genomic Stability and DNA Repair (2021EK3)
DNA Replication and Genome Instability: From Mechanism to Disease (2019A1)

Web Desc
Genomic Instability and DNA Repair joint with DNA Replication and Recombination Organizer(s): Julia Promisel Cooper, Marco F. Foiani and Geneviève Almouzni Date: April 02 - 06, 2017 Location: Santa Fe Community Convention Center, Santa Fe, NM, USA Sponsored by AstraZeneca, Bayer HealthCare Pharmaceuticals, Editas Medicine, Inc., EMD Serono Research and Development Institute, Inc., Journal of Molecular Cell Biology (JMCB) and TESARO, Inc. Summary of Meeting: Genome stability is the foundation upon which all cellular and organismal processes depend. This conference will grapple with the intricate array of biochemical reactions orchestrated by the cell to replicate, repair and segregate chromosomes accurately despite constant threats from spontaneous and environmentally-induced damage. Defects in these reactions lead to genomic instability, a confirmed driver of cancer and degenerative diseases. Fascinating and therapeutically crucial questions remain about the mechanisms underlying chromosome stability, and cross-disciplinary approaches are required to address them. How do epigenetic chromatin marks influence repair of underlying DNA sequences, and how can we predict the effects of chemotherapeutic agents that alter such marks? To what extent is the nucleus organized into subdomains with distinct functions; how are these subdomains altered when cells move or differentiate? How are the myriad helicases, nucleases and polymerases coordinated to safeguard genome stability, why are these molecules often mutated in human disease, and how can we ameliorate the effects of such mutations? What is the array of strategies available to cancer cells as they achieve unlimited proliferation? This conference has a history of bringing together investigators from diverse subfields who otherwise rarely meet. Cutting-edge concepts in translational, genomic, cellular, molecular, RNA and structural biology will be dissected to take the conversation to unprecedented levels of depth and breadth. The concurrent conference on “DNA Replication and Recombination” will provide additional opportunities for cross-talk. Both conferences are committed to nurturing interactions among longtime experts in the field with students, postdocs and investigators new to the field. Scholarship Deadline: December 5 2016 Discounted Abstract Deadline: December 5 2016 Abstract Deadline: January 12 2017 Discounted Registration Deadline: February 2 2017 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Genomic Instability and DNA Repair

joint with DNA Replication and Recombination

Organizer(s): Julia Promisel Cooper, Marco F. Foiani and Geneviève Almouzni

Date: April 02 - 06, 2017
Location: Santa Fe Community Convention Center, Santa Fe, NM, USA

Sponsored by AstraZeneca, Bayer HealthCare Pharmaceuticals, Editas Medicine, Inc., EMD Serono Research and Development Institute, Inc., Journal of Molecular Cell Biology (JMCB) and TESARO, Inc.

Summary of Meeting:

Genome stability is the foundation upon which all cellular and organismal processes depend. This conference will grapple with the intricate array of biochemical reactions orchestrated by the cell to replicate, repair and segregate chromosomes accurately despite constant threats from spontaneous and environmentally-induced damage. Defects in these reactions lead to genomic instability, a confirmed driver of cancer and degenerative diseases. Fascinating and therapeutically crucial questions remain about the mechanisms underlying chromosome stability, and cross-disciplinary approaches are required to address them. How do epigenetic chromatin marks influence repair of underlying DNA sequences, and how can we predict the effects of chemotherapeutic agents that alter such marks? To what extent is the nucleus organized into subdomains with distinct functions; how are these subdomains altered when cells move or differentiate? How are the myriad helicases, nucleases and polymerases coordinated to safeguard genome stability, why are these molecules often mutated in human disease, and how can we ameliorate the effects of such mutations? What is the array of strategies available to cancer cells as they achieve unlimited proliferation? This conference has a history of bringing together investigators from diverse subfields who otherwise rarely meet. Cutting-edge concepts in translational, genomic, cellular, molecular, RNA and structural biology will be dissected to take the conversation to unprecedented levels of depth and breadth. The concurrent conference on “DNA Replication and Recombination” will provide additional opportunities for cross-talk. Both conferences are committed to nurturing interactions among longtime experts in the field with students, postdocs and investigators new to the field.

Scholarship Deadline: December 5 2016

Discounted Abstract Deadline: December 5 2016

Abstract Deadline: January 12 2017

Discounted Registration Deadline: February 2 2017

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support for this conference from:

March of Dimes Foundation, Grant No. 4-FY16-317

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, April 02 \| 4:00PM - 8:00PM Arrival and Registration Room: Sweeney Ballroom Foyer
Sunday, April 02 \| 6:00PM - 8:00PM Welcome Mixer Room: Sweeney F No registration fees are used to fund alcohol served at this function.
Monday, April 03 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakouts
Monday, April 03 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Sweeney Ballroom A-E Speaker 1 of 5 * Julia Promisel Cooper, NCI, National Institutes of Health, USA
Monday, April 03 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Sweeney Ballroom A-E Speaker 2 of 5 * Scott Keeney, HHMI/Memorial Sloan Kettering Cancer Center, USA
Monday, April 03 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Sweeney Ballroom A-E Speaker 3 of 5 Tatsuya Hirano, RIKEN, Japan Condensin-Based Chromosome Organization
Monday, April 03 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Sweeney Ballroom A-E Speaker 4 of 5 Johannes C. Walter, Harvard Medical School, USA Mechanisms of Replication-Coupled Repair
Monday, April 03 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Sweeney Ballroom A-E Coffee Break
Monday, April 03 \| 9:50AM - 12:00PM Mechanisms of DNA Repair Room: Sweeney Ballroom A-B Speaker 1 of 6 * Timothy C. Humphrey, University of Oxford, UK
Monday, April 03 \| 9:50AM - 12:00PM Mechanisms of DNA Repair Room: Sweeney Ballroom A-B Speaker 2 of 6 Wei Yang, NIDDK, National Institutes of Health, USA Structural Insights into Translesion DNA Polymerases
Monday, April 03 \| 9:50AM - 12:00PM Mechanisms of DNA Repair Room: Sweeney Ballroom A-B Speaker 3 of 6 James E. Haber, Brandeis University, USA Short Talk: Rad51-Mediated Double-Strand Break Repair and Mismatch Correction of Highly Diverged Substrates
Monday, April 03 \| 9:50AM - 12:00PM Mechanisms of DNA Repair Room: Sweeney Ballroom A-B Speaker 4 of 6 Joseph J. Loparo, Harvard Medical School, USA Short Talk: Single-Molecule Imaging of Non-Homologous End Joining
Monday, April 03 \| 9:50AM - 12:00PM Mechanisms of DNA Repair Room: Sweeney Ballroom A-B Speaker 5 of 6 Michael D. Stone, University of California, Santa Cruz, USA Mechanical Transitions in Long Duplex Telomere DNA Molecules
Monday, April 03 \| 9:50AM - 12:00PM Mechanisms of DNA Repair Room: Sweeney Ballroom A-B Speaker 6 of 6 Fena Ochs, University of Copenhagen, Denmark Short Talk: Dynamic Chromatin Superstructures Safeguard Integrity of Nuclear Compartments Challenged by DNA Breakage
Monday, April 03 \| 9:50AM - 12:00PM Replication/Repair Structure and Function This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 1 of 6 * John F.X. Diffley, Francis Crick Institute, UK
Monday, April 03 \| 9:50AM - 12:00PM Replication/Repair Structure and Function This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 2 of 6 Michael E. O'Donnell, Rockefeller University, USA Structure and Function of the Eukaryotic Replisome
Monday, April 03 \| 9:50AM - 12:00PM Replication/Repair Structure and Function This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 3 of 6 Tyler H. Stanage, Francis Crick Institute, UK Short Talk: The Escherichia coli RarA Protein is Involved in the Switch between DNA Replication and Translesion Synthesis in vivo
Monday, April 03 \| 9:50AM - 12:00PM Replication/Repair Structure and Function This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 4 of 6 Karlene A. Cimprich, Stanford University, USA When RNA Meets DNA: Dangerous Liaisons in the Genome
Monday, April 03 \| 9:50AM - 12:00PM Replication/Repair Structure and Function This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 5 of 6 Alessandro Costa, Francis Crick Institute, UK Cryo-EM Approaches to Understanding the Eukaryotic Replisome
Monday, April 03 \| 9:50AM - 12:00PM Replication/Repair Structure and Function This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 6 of 6 Matthew L. Bochman, Indiana University, USA Short Talk: Hrq1, The Yeast Homolog of RecQ4, Inhibits Telomerase Activity on Long Telomeres
Monday, April 03 \| 12:00PM - 5:00PM On Own for Lunch
Monday, April 03 \| 12:00PM - 1:00PM Poster Setup Room: Sweeney F, Main Level Breakouts
Monday, April 03 \| 1:00PM - 10:00PM Poster Viewing Room: Sweeney F, Main Level Breakouts
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Genome Instability and DNA Repair I Room: Sweeney Ballroom A-B Speaker 1 of 9 * James E. Haber, Brandeis University, USA
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Genome Instability and DNA Repair I Room: Sweeney Ballroom A-B Speaker 2 of 9 Elena Balkanska-Sinclair, Duke University, USA The BRD4-NUT Fusion Protein from Nut-Midline Carcinoma modulates DNA Damage Signaling and Ionizing Radiation Response
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Genome Instability and DNA Repair I Room: Sweeney Ballroom A-B Speaker 3 of 9 Michael M. Cox, University of Wisconsin-Madison, USA Ionizing Radiation Resistance in Experimentally Evolved Escherichia coli Populations
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Genome Instability and DNA Repair I Room: Sweeney Ballroom A-B Speaker 4 of 9 Nitika Taneja, NCI, National Institutes of Health, USA SNF2 Family Protein Fft3 Suppresses Nucleosome Turnover to Promote Epigenetic Inheritance and Proper Replication
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Genome Instability and DNA Repair I Room: Sweeney Ballroom A-B Speaker 5 of 9 Ryan M. Baxley, University of Minnesota, USA Progressive Genomic Instability and Telomere Erosion in Human Cells following Inactivation of a Single MCM10 Allele
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Genome Instability and DNA Repair I Room: Sweeney Ballroom A-B Speaker 6 of 9 Michael H. Hauer, Friedrich Miescher Institute for Biomedical Research, Switzerland Histone Degradation in Response to DNA Damage Enhances Chromatin Dynamics and Recombination Rates
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Genome Instability and DNA Repair I Room: Sweeney Ballroom A-B Speaker 7 of 9 Mariano Labrador-San Jose, University of Tennessee, USA Components of the DNA Damage Response Pathway, ATR and ATM, Modulate Chromatin Insulator Activity through Phosphorylation of Histone H2Av at Insulator Sites
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Genome Instability and DNA Repair I Room: Sweeney Ballroom A-B Speaker 8 of 9 Mitch McVey, Tufts University, USA Coordination of ATPase and Polymerase Activities of Drosophila DNA Polymerase Theta during Interstrand Crosslink and Alternative End-Joining Repair of Double-Strand Breaks
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Genome Instability and DNA Repair I Room: Sweeney Ballroom A-B Speaker 9 of 9 Hilda A. Pickett, Children's Medical Research Institute, Australia BLM and SLX4 Play Opposing Roles in Recombination-Dependent Replication at Human Telomeres
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Recombination and Repair This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 1 of 8 Tracey E. Beyer, Biotech Research and Innovation Centre, Denmark Ontogeny of Genome Rearrangements in Budding Yeast
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Recombination and Repair This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 2 of 8 * Simon N. Powell, Memorial Sloan Kettering Cancer Center, USA Replication Fork Cleavage Occurs within 100bp from Local ATM Signaling of Site-Specific DNA Replication Block in Human Cells
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Recombination and Repair This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 3 of 8 Erin Hannah Sybouts, University of Texas Health Science Center at San Antonio, USA Recombination and BLM Helicase Compensate for Replication Fork Defects in the Absence of 53BP1 Protein
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Recombination and Repair This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 4 of 8 Shane McDevitt, Temple University Lewis Katz School of Medicine, USA Mechanisms of RNA-Transcript Templated DNA Recombinational Repair Promoted by RAD52
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Recombination and Repair This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 5 of 8 Susanne S. C. Bantele, Max Planck Institute of Biochemistry, Germany Regulation of the Conserved Chromatin Remodeler Fun30SMARCAD1 at DNA Double-Strand Breaks
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Recombination and Repair This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 6 of 8 Walter J. Chazin, Vanderbilt University, USA Mechanisms for Counting and Handoff by Human DNA Primase- A Role for the 4Fe-4S Cluster?
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Recombination and Repair This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 7 of 8 Holger Puchta, Karlsruhe Institute of Technology, Germany The RTR Complex Partner RMI2 and the DNA Helicase RTEL1 Are Both Independently Involved in Preserving the Stability of 45S rDNA Repeats in Arabidopsis thaliana
Monday, April 03 \| 2:30PM - 4:30PM Workshop 1: Recombination and Repair This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 8 of 8 Christian Biertuempfel, Max Planck Institute of Biochemistry, Germany DNA Recognition Features of Human Holliday Junction Resolvase GEN1
Monday, April 03 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom Foyer
Monday, April 03 \| 5:00PM - 7:00PM RNA Metabolism and Genome Stability Room: Sweeney Ballroom A-B Speaker 1 of 7 * Hengyao Niu, Indiana University Bloomington, USA
Monday, April 03 \| 5:00PM - 7:00PM RNA Metabolism and Genome Stability Room: Sweeney Ballroom A-B Speaker 2 of 7 Vihandha Wickramasinghe, Peter MacCallum Cancer Centre, Australia Effects of Altered RNA Processing on Genome Stability and the Proteome
Monday, April 03 \| 5:00PM - 7:00PM RNA Metabolism and Genome Stability Room: Sweeney Ballroom A-B Speaker 3 of 7 Frédéric L. Chedin, University of California, Davis, USA Short Talk: R-Loop Formation is a Hallmark of Active Early Replication Origins in Mammalian Genomes
Monday, April 03 \| 5:00PM - 7:00PM RNA Metabolism and Genome Stability Room: Sweeney Ballroom A-B Speaker 4 of 7 Julius Brennecke, IMBA - Institut für Molekulare Biotechnologie GmbH, Austria An RNA-Based Genome Immune System Safeguards Genome Stability
Monday, April 03 \| 5:00PM - 7:00PM RNA Metabolism and Genome Stability Room: Sweeney Ballroom A-B Speaker 5 of 7 Eric A. Hunt, New England Biolabs, USA Short Talk: Prokaryotic Argonautes and their Potential as New Molecular Tools
Monday, April 03 \| 5:00PM - 7:00PM RNA Metabolism and Genome Stability Room: Sweeney Ballroom A-B Speaker 6 of 7 Alice Meroni, University of Milan, Italy Short Talk: DNA Polymerase eta Sensitizes Cells to Nucleotide Pool Deprivation in Absence of RNase H
Monday, April 03 \| 5:00PM - 7:00PM RNA Metabolism and Genome Stability Room: Sweeney Ballroom A-B Speaker 7 of 7 Francesca Storici, Georgia Institute of Technology, USA Short Talk: Double-Strand Break Repair by Transcript RNA Is Stimulated by Rad52 and Requires Limited End Resection
Monday, April 03 \| 5:00PM - 7:00PM Starting Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Covering meiotic initiation, somatic lesion formation, DSB processing. Speaker 1 of 6 * Bernard de Massy, Institut de Génétique Humaine, France
Monday, April 03 \| 5:00PM - 7:00PM Starting Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Covering meiotic initiation, somatic lesion formation, DSB processing. Speaker 2 of 6 Scott Keeney, HHMI/Memorial Sloan Kettering Cancer Center, USA Breaking and Chewing DNA during Meiosis
Monday, April 03 \| 5:00PM - 7:00PM Starting Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Covering meiotic initiation, somatic lesion formation, DSB processing. Speaker 3 of 6 Florencia M. Pratto, NIDDK, National Institutes of Health, USA Linking Replication and Meiotic Recombination Initiation in Mammals
Monday, April 03 \| 5:00PM - 7:00PM Starting Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Covering meiotic initiation, somatic lesion formation, DSB processing. Speaker 4 of 6 Kara A. Bernstein, University of Pittsburgh School of Medicine, USA Short Talk: The Function of the Shu Complex and the Rad51 Paralogs in Repair of Replication Intermediate by Promotion of Rad51 Presynaptic Filament Assembly
Monday, April 03 \| 5:00PM - 7:00PM Starting Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Covering meiotic initiation, somatic lesion formation, DSB processing. Speaker 5 of 6 Maria Jasin, Memorial Sloan Kettering Cancer Center, USA Protecting the Genome by Homologous Recombination
Monday, April 03 \| 5:00PM - 7:00PM Starting Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Covering meiotic initiation, somatic lesion formation, DSB processing. Speaker 6 of 6 Sofija Mijic, Linköping University, Sweden Short Talk: Replication Fork Reversal Triggers Fork Degradation in BRCA2-Defective Cells
Monday, April 03 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney F, Main Level Breakouts No registration fees are used to fund alcohol served at this function.
Monday, April 03 \| 7:30PM - 10:00PM Poster Session 1 Room: Sweeney F, Main Level Breakouts
Tuesday, April 04 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakouts
Tuesday, April 04 \| 8:00AM - 11:00AM Interplay between Chromatin Structure and DNA Replication/Re pair (Joint) Room: Sweeney Ballroom A-E Speaker 1 of 9 * Anja Groth, University of Copenhagen, Denmark
Tuesday, April 04 \| 8:00AM - 11:00AM Interplay between Chromatin Structure and DNA Replication/Re pair (Joint) Room: Sweeney Ballroom A-E Speaker 2 of 9 * Jennifer A. Cobb, University of Calgary, Canada
Tuesday, April 04 \| 8:00AM - 11:00AM Interplay between Chromatin Structure and DNA Replication/Re pair (Joint) Room: Sweeney Ballroom A-E Speaker 3 of 9 Geneviève Almouzni, Centre National de la Recherche Scientifique, France Shaping Chromatin in the Nucleus, the Bricks and the Architects
Tuesday, April 04 \| 8:00AM - 11:00AM Interplay between Chromatin Structure and DNA Replication/Re pair (Joint) Room: Sweeney Ballroom A-E Speaker 4 of 9 Gary Karpen, University of California, Berkeley, USA Regulation of DNA Repair in Heterochromatin and Euchromatin
Tuesday, April 04 \| 8:00AM - 11:00AM Interplay between Chromatin Structure and DNA Replication/Re pair (Joint) Room: Sweeney Ballroom A-E Speaker 5 of 9 Francesca Mattiroli, HHMI/Colorado University Boulder, USA Short Talk: DNA-Mediated Association of Two Histone-Bound CAF-1 Complexes Drives Tetrasome Assembly in the Wake of DNA Replication
Tuesday, April 04 \| 8:00AM - 11:00AM Interplay between Chromatin Structure and DNA Replication/Re pair (Joint) Room: Sweeney Ballroom A-E Coffee Break
Tuesday, April 04 \| 8:00AM - 11:00AM Interplay between Chromatin Structure and DNA Replication/Re pair (Joint) Room: Sweeney Ballroom A-E Speaker 7 of 9 Robert A. Martienssen, Cold Spring Harbor Laboratory, USA RNAi Promotes Heterochromatic Silencing through Replication-Coupled Release of RNA Polymerase II
Tuesday, April 04 \| 8:00AM - 11:00AM Interplay between Chromatin Structure and DNA Replication/Re pair (Joint) Room: Sweeney Ballroom A-E Speaker 8 of 9 Bernard de Massy, Institut de Génétique Humaine, France The Control of Initiation of Meiotic Recombination by PRDM9
Tuesday, April 04 \| 8:00AM - 11:00AM Interplay between Chromatin Structure and DNA Replication/Re pair (Joint) Room: Sweeney Ballroom A-E Speaker 9 of 9 Philipp Oberdoerffer, NCI, National Institutes of Health, USA Short Talk: Replication Stress Shapes a Protective Chromatin Environment Across Fragile Genomic Regions
Tuesday, April 04 \| 11:00AM - 5:00PM On Own for Lunch
Tuesday, April 04 \| 11:00AM - 1:00PM Poster Setup Room: Sweeney F, Main Level Breakouts
Tuesday, April 04 \| 1:00PM - 10:00PM Poster Viewing Room: Sweeney F, Main Level Breakouts
Tuesday, April 04 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom Foyer
Tuesday, April 04 \| 5:00PM - 7:00PM Cell Cycle Regulation of DNA Damage Response Room: Sweeney Ballroom A-B Speaker 1 of 6 * Frédéric L. Chedin, University of California, Davis, USA
Tuesday, April 04 \| 5:00PM - 7:00PM Cell Cycle Regulation of DNA Damage Response Room: Sweeney Ballroom A-B Speaker 2 of 6 Tanya T. Paull, University of Texas at Austin, USA Double-Strand Break Repair Factors and R-Loop-Mediated Genomic Instability
Tuesday, April 04 \| 5:00PM - 7:00PM Cell Cycle Regulation of DNA Damage Response Room: Sweeney Ballroom A-B Speaker 3 of 6 David Cortez, Vanderbilt University School of Medicine, USA Regulation of Replication Fork Stability by Single-Stranded DNA Binding Proteins
Tuesday, April 04 \| 5:00PM - 7:00PM Cell Cycle Regulation of DNA Damage Response Room: Sweeney Ballroom A-B Speaker 4 of 6 Kyle M. Miller, USA Chromatin Regulation of the DNA Damage Response
Tuesday, April 04 \| 5:00PM - 7:00PM Cell Cycle Regulation of DNA Damage Response Room: Sweeney Ballroom A-B Speaker 5 of 6 Michael P. Sheetz, Mechanobiology Institute, National University of Singapore, Singapore Short Talk: DNA Damage Causes¬ Rapid Accumulation of Phosphoinositides to Recruit ATR but not ATM
Tuesday, April 04 \| 5:00PM - 7:00PM Cell Cycle Regulation of DNA Damage Response Room: Sweeney Ballroom A-B Speaker 6 of 6 Linda J. Kenney, National University of Singapore, Singapore Short Talk: Salmonella Typhimurium forms Biofilms on Solid Tumors
Tuesday, April 04 \| 5:00PM - 7:00PM Regulating Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Cell cycle, site choice, partner choice, pathway choice. Speaker 1 of 6 * Xiaolan Zhao, Memorial Sloan Kettering Cancer Center, USA
Tuesday, April 04 \| 5:00PM - 7:00PM Regulating Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Cell cycle, site choice, partner choice, pathway choice. Speaker 2 of 6 Lorraine S. Symington, Columbia University, USA DNA End Resection and Repair Pathway Choice
Tuesday, April 04 \| 5:00PM - 7:00PM Regulating Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Cell cycle, site choice, partner choice, pathway choice. Speaker 3 of 6 Jennifer A. Cobb, University of Calgary, Canada Nej1 Regulates Repair Pathway Choice by Inhibiting Dna2-Sgs1 Mediated Resection
Tuesday, April 04 \| 5:00PM - 7:00PM Regulating Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Cell cycle, site choice, partner choice, pathway choice. Speaker 4 of 6 Aurele Piazza, Ecole Normale Superieure de Lyon, France Short Talk: Multi-Invasions Are Recombination Byproducts that Induce Chromosomal Rearrangements
Tuesday, April 04 \| 5:00PM - 7:00PM Regulating Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Cell cycle, site choice, partner choice, pathway choice. Speaker 5 of 6 Eric C. Greene, Columbia University, USA Single-Molecule Studies of Recombination Pathways
Tuesday, April 04 \| 5:00PM - 7:00PM Regulating Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Cell cycle, site choice, partner choice, pathway choice. Speaker 6 of 6 Sneha Saxena, Indian Institute of Science, India Short Talk: RAD51 Paralog XRCC2 Suppresses Pathological Replication Fork Progression
Tuesday, April 04 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney F, Main Level Breakouts No registration fees are used to fund alcohol served at this function.
Tuesday, April 04 \| 7:30PM - 10:00PM Poster Session 2 Room: Sweeney F, Main Level Breakouts
Wednesday, April 05 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakouts
Wednesday, April 05 \| 7:30AM - 8:00AM Poster Setup Room: Sweeney F, Main Level Breakouts
Wednesday, April 05 \| 8:00AM - 5:00PM Poster Viewing Room: Sweeney F, Main Level Breakouts
Wednesday, April 05 \| 8:00AM - 11:00AM Nuclear Dynamics and Genome Stability Room: Sweeney Ballroom A-B Speaker 1 of 9 * Arnab Ray Chaudhuri, Erasmus University Medical Center, Netherlands
Wednesday, April 05 \| 8:00AM - 11:00AM Nuclear Dynamics and Genome Stability Room: Sweeney Ballroom A-B Speaker 2 of 9 Marco F. Foiani, Instituto FIRC di Oncologia Molecolare, Italy An Integrated ATR, ATM and mTOR-Mechanical Network Controlling Nuclear Plasticity and Cell Migration
Wednesday, April 05 \| 8:00AM - 11:00AM Nuclear Dynamics and Genome Stability Room: Sweeney Ballroom A-B Speaker 3 of 9 Angela Taddei, Institut Curie, France Nuclear Organization and Chromatin Status Modulate Homologous Recombination Efficiency and Outcome
Wednesday, April 05 \| 8:00AM - 11:00AM Nuclear Dynamics and Genome Stability Room: Sweeney Ballroom A-B Speaker 4 of 9 Irene Chiolo, University of Southern California, USA Short Talk: Highways for Repair: Nuclear Myosins and Actin Filaments Relocalize Heterochromatic DNA Breaks to the Nuclear Periphery
Wednesday, April 05 \| 8:00AM - 11:00AM Nuclear Dynamics and Genome Stability Room: Sweeney Ballroom A-B Coffee Break
Wednesday, April 05 \| 8:00AM - 11:00AM Nuclear Dynamics and Genome Stability Room: Sweeney Ballroom A-B Speaker 6 of 9 Martin W. Hetzer, The Salk Institute for Biological Studies, USA How the Nuclear Membrane Controls Genome Function
Wednesday, April 05 \| 8:00AM - 11:00AM Nuclear Dynamics and Genome Stability Room: Sweeney Ballroom A-B Speaker 7 of 9 Emmanuelle Fabre, Hopital St Louis, France Short Talk: DNA Damage Increases Chromatin Stiffening in Budding Yeast
Wednesday, April 05 \| 8:00AM - 11:00AM Nuclear Dynamics and Genome Stability Room: Sweeney Ballroom A-B Speaker 8 of 9 Neil T. Umbreit, Dana-Farber Cancer Institute, USA Short Talk: Chromosome Bridge Resolution Requires Mechanical Forces from Actin-Based Contractility
Wednesday, April 05 \| 8:00AM - 11:00AM Nuclear Dynamics and Genome Stability Room: Sweeney Ballroom A-B Speaker 9 of 9 Peter Ly, University of California San Diego, USA Short Talk: Mitotic Errors Promote Chromosome Shattering and DNA Break Repair by Non-Homologous End Joining
Wednesday, April 05 \| 8:00AM - 11:00AM Replication Fork Progression and Restart This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 1 of 9 * Anne D. Donaldson, University of Aberdeen, UK
Wednesday, April 05 \| 8:00AM - 11:00AM Replication Fork Progression and Restart This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 2 of 9 Kenneth J. Marians, Memorial Sloan Kettering Cancer Center, USA Imaging Individual Replisomes Reveals Independence and Decoupling of Polymerases During Replication
Wednesday, April 05 \| 8:00AM - 11:00AM Replication Fork Progression and Restart This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 3 of 9 Anja Groth, University of Copenhagen, Denmark Chromatin Replication and Epigenome Maintenance
Wednesday, April 05 \| 8:00AM - 11:00AM Replication Fork Progression and Restart This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 4 of 9 Alberto Ciccia, Columbia University, USA Short Talk: Restoration of Fork Stability in BRCA1- and BRCA2-Deficient Cells
Wednesday, April 05 \| 8:00AM - 11:00AM Replication Fork Progression and Restart This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Coffee Break
Wednesday, April 05 \| 8:00AM - 11:00AM Replication Fork Progression and Restart This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 6 of 9 Xiaolan Zhao, Memorial Sloan Kettering Cancer Center, USA Smc5/6-Mediated Control of Recombinational Repair is Critical for Genome Duplication
Wednesday, April 05 \| 8:00AM - 11:00AM Replication Fork Progression and Restart This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 7 of 9 Advaitha Madireddy, Albert Einstein Collge of Medicine, USA Short Talk: FANCD2 Facilitates DNA Replication through Common Fragile Sites
Wednesday, April 05 \| 8:00AM - 11:00AM Replication Fork Progression and Restart This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 8 of 9 Joseph L. Stodola, Washington University School of Medicine, USA Short Talk: Kinetic Analysis of Lagging Strand Replication and Okazaki Fragment Maturation
Wednesday, April 05 \| 8:00AM - 11:00AM Replication Fork Progression and Restart This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 9 of 9 Joseph Yeeles, MRC Laboratory of Molecular Biology, UK Short Talk: How the Eukaryotic Replisome Responds to DNA Damage in the Leading- and Lagging-Strand Templates
Wednesday, April 05 \| 11:00AM - 12:00PM Lunch Room: Sweeney F, Main Level Breakouts
Wednesday, April 05 \| 12:00PM - 2:30PM Poster Session 3 Room: Sweeney F, Main Level Breakouts
Wednesday, April 05 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom Foyer
Wednesday, April 05 \| 5:00PM - 7:00PM DNA Repair and Human Diseases Room: Sweeney Ballroom A-B Speaker 1 of 6 * Hilda A. Pickett, Children's Medical Research Institute, Australia
Wednesday, April 05 \| 5:00PM - 7:00PM DNA Repair and Human Diseases Room: Sweeney Ballroom A-B Speaker 2 of 6 Agnel Sfeir, New York University School of Medicine, USA Single-Molecule Analysis of mtDNA Replication Uncovers the Basis of the Common Deletion
Wednesday, April 05 \| 5:00PM - 7:00PM DNA Repair and Human Diseases Room: Sweeney Ballroom A-B Speaker 3 of 6 Cecilia Cotta-Ramusino, Tessera Therapeutics, USA Short Talk: Characterization of the Interplay between DNA Repair and CRISPR/Cas9-Induced DNA Lesions at an Endogenous Locus
Wednesday, April 05 \| 5:00PM - 7:00PM DNA Repair and Human Diseases Room: Sweeney Ballroom A-B Speaker 4 of 6 Simon J. Boulton, Francis Crick Institute, UK Mechanistic Insights into Telomere Dysfunction Disorders
Wednesday, April 05 \| 5:00PM - 7:00PM DNA Repair and Human Diseases Room: Sweeney Ballroom A-B Speaker 5 of 6 Madalena Tarsounas, University of Oxford, UK Short Talk: MUS81 Nuclease Activity Is Essential for Replication Stress Tolerance and Chromosome Segregation in BRCA2-Deficient Cells
Wednesday, April 05 \| 5:00PM - 7:00PM DNA Repair and Human Diseases Room: Sweeney Ballroom A-B Speaker 6 of 6 Janet Partridge, St Jude Children's Research Hospital, USA Short Talk: Histone H3G34R Mutation Causes Replicative Stress, Defective Homologous Recombination and Genomic Instability in Fission Yeast
Wednesday, April 05 \| 5:00PM - 7:00PM Replication Initiation Mechanisms This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 1 of 6 * Kenneth J. Marians, Memorial Sloan Kettering Cancer Center, USA
Wednesday, April 05 \| 5:00PM - 7:00PM Replication Initiation Mechanisms This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 2 of 6 Stephen P. Bell, Massachusetts Institute of Technology, USA Mechanism and Timing of Mcm2-7 Ring Closure During Origin Licensing
Wednesday, April 05 \| 5:00PM - 7:00PM Replication Initiation Mechanisms This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 3 of 6 Stephen D. Bell, Indiana University, USA DNA Replication in the Archaea
Wednesday, April 05 \| 5:00PM - 7:00PM Replication Initiation Mechanisms This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 4 of 6 Heath Murray, Newcastle University, UK Short Talk: A New Bacterial Replication Origin Element Specifies Single-Strand Initiator Binding
Wednesday, April 05 \| 5:00PM - 7:00PM Replication Initiation Mechanisms This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 5 of 6 Anne D. Donaldson, University of Aberdeen, UK The Conserved Role of Rif1 as a Substrate-Targeting Subunit of Protein Phosphatase 1
Wednesday, April 05 \| 5:00PM - 7:00PM Replication Initiation Mechanisms This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 6 of 6 Dominik Boos, University of Duisburg-Essen, Germany Short Talk: MTBP Is an Essential Replication Initiation Factor with Vertebrate-Specific and Sld7-Like Features
Wednesday, April 05 \| 7:00PM - 7:00PM On Own for Dinner
Thursday, April 06 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakouts
Thursday, April 06 \| 8:00AM - 11:00AM Replication Fork Establishment and Replication-Coupled Repai r (Joint) Room: Sweeney Ballroom A-E Speaker 1 of 9 * Jeannine Gerhardt, Weill Cornell Medicine, USA
Thursday, April 06 \| 8:00AM - 11:00AM Replication Fork Establishment and Replication-Coupled Repai r (Joint) Room: Sweeney Ballroom A-E Speaker 2 of 9 * Karlene A. Cimprich, Stanford University, USA
Thursday, April 06 \| 8:00AM - 11:00AM Replication Fork Establishment and Replication-Coupled Repai r (Joint) Room: Sweeney Ballroom A-E Speaker 3 of 9 James M. Berger, Johns Hopkins University School of Medicine, USA Physical Mechanisms for Initiating DNA Replication in Cells
Thursday, April 06 \| 8:00AM - 11:00AM Replication Fork Establishment and Replication-Coupled Repai r (Joint) Room: Sweeney Ballroom A-E Speaker 4 of 9 Agata Smogorzewska, Rockefeller University, USA Stress Response at the Replication Fork
Thursday, April 06 \| 8:00AM - 11:00AM Replication Fork Establishment and Replication-Coupled Repai r (Joint) Room: Sweeney Ballroom A-E Speaker 5 of 9 Eric J. Brown, Perelman School of Medicine, University of Pennsylvania, USA Short Talk: Characterizing Replisome Ubiquitination upon Fork Stalling
Thursday, April 06 \| 8:00AM - 11:00AM Replication Fork Establishment and Replication-Coupled Repai r (Joint) Room: Sweeney Ballroom A-E Coffee Break
Thursday, April 06 \| 8:00AM - 11:00AM Replication Fork Establishment and Replication-Coupled Repai r (Joint) Room: Sweeney Ballroom A-E Speaker 7 of 9 André Nussenzweig, NCI, National Institutes of Health, USA DNA Breaks and End-Resection Measured Genome-Wide by End Sequencing (END-seq)
Thursday, April 06 \| 8:00AM - 11:00AM Replication Fork Establishment and Replication-Coupled Repai r (Joint) Room: Sweeney Ballroom A-E Speaker 8 of 9 Helle D. Ulrich, Institute of Molecular Biology, Germany Coordination of DNA Damage Bypass with Genome Replication and Checkpoint Signaling
Thursday, April 06 \| 8:00AM - 11:00AM Replication Fork Establishment and Replication-Coupled Repai r (Joint) Room: Sweeney Ballroom A-E Speaker 9 of 9 Stephane Koundrioukoff, Institute Gustave Roussy, France Short Talk: DNA Replication Compensation: A Two Steps Mechanism
Thursday, April 06 \| 11:00AM - 5:00PM On Own for Lunch
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Genome Instability and DNA Repair II Room: Sweeney Ballroom A-B Speaker 1 of 9 * Michael P. Sheetz, Mechanobiology Institute, National University of Singapore, Singapore
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Genome Instability and DNA Repair II Room: Sweeney Ballroom A-B Speaker 2 of 9 Katharina Schlacher, MD Anderson Cancer Center, USA Epigenetics-Enabled MRE11 Replication Restart by p53 Promotes Replication Pathway Homeostasis to Suppress Opportunistic Transcription Reprogramming
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Genome Instability and DNA Repair II Room: Sweeney Ballroom A-B Speaker 3 of 9 Kristijan Ramadan, University of Oxford, UK SPRTN Is a Novel Mammalian Protease with the Central Role in DNA Replication-Coupled DNA-Protein Crosslink Repair
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Genome Instability and DNA Repair II Room: Sweeney Ballroom A-B Speaker 4 of 9 Jason Sheltzer, Cold Spring Harbor Laboratory, USA Single-Chromosome Aneuploidy Commonly Functions as a Tumor Suppressor but Can Drive Genome Evolution
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Genome Instability and DNA Repair II Room: Sweeney Ballroom A-B Speaker 5 of 9 Manuel Stucki, University of Zurich, Switzerland TOPBP1 Cooperate with TCOF1/Treacle in the Nucleolar Response to DNA Double-Strand Breaks
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Genome Instability and DNA Repair II Room: Sweeney Ballroom A-B Speaker 6 of 9 Maria Teresa Teixeira, CNRS – UMR 8226, France Telomere Replication in the Absence of Telomerase: Failure, Repair and Adaptation
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Genome Instability and DNA Repair II Room: Sweeney Ballroom A-B Speaker 7 of 9 Johannes van den Boom, University of Duisburg-Essen, Germany The AAA-ATPase VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Genome Instability and DNA Repair II Room: Sweeney Ballroom A-B Speaker 8 of 9 Catherine H. Freudenreich, Tufts University, USA Cytosine Deamination Mediates R-Loop Dependent CAG Repeat Fragility and Instability
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Genome Instability and DNA Repair II Room: Sweeney Ballroom A-B Speaker 9 of 9 Muwen Kong, Columbia University Medical Center, USA Auto-PARylation Switches PARP1 Search Mechanism from Three-Dimensional Diffusion to Anomalous One-Dimensional Sliding
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Replication This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 1 of 6 * Linda B. Bloom, University of Florida, USA Active Sliding Clamp Opening in Three Steps
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Replication This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 2 of 6 Christopher Sansam, Oklahoma Medical Research Foundation, USA DNA Replication Timing during Development Anticipates Transcriptional Programs and Parallels Enhancer Activation
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Replication This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 3 of 6 Boris Pfander, Max Planck Institute of Biochemistry, Germany Robust Replication Control by Temporal Gaps between Licensing and Firing Phases
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Replication This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 4 of 6 Hasan Yardimci, Francis Crick Institute, UK Super-Resolution Fluorescence Imaging of DNA Replication Intermediates
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Replication This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 5 of 6 Jon Baxter, University of Sussex, UK Transcription Promotes Replication Fork Rotation and Double-Stranded DNA Intertwining via a Cohesin-Dependent Pathway
Thursday, April 06 \| 2:30PM - 4:30PM Workshop 2: Replication This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Speaker 6 of 6 Ivan Psakhye, IFOM, FIRC Institute of Molecular Oncology, Italy DDK-Mediated Regulation of the deSUMOylating Enzyme Ulp2 Facilitates DNA Replication Initiation
Thursday, April 06 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom Foyer
Thursday, April 06 \| 5:00PM - 6:45PM Telomeres and Centromeres Room: Sweeney Ballroom A-B Speaker 1 of 5 * Maria Teresa Teixeira, CNRS – UMR 8226, France
Thursday, April 06 \| 5:00PM - 6:45PM Telomeres and Centromeres Room: Sweeney Ballroom A-B Speaker 2 of 5 Titia de Lange, Rockefeller University, USA How Shelterin Solves the Telomere End-Protection Problem
Thursday, April 06 \| 5:00PM - 6:45PM Telomeres and Centromeres Room: Sweeney Ballroom A-B Speaker 3 of 5 Kerry S. Bloom, University of North Carolina at Chapel Hill, USA The Molecular Basis for the Centromere Spring
Thursday, April 06 \| 5:00PM - 6:45PM Telomeres and Centromeres Room: Sweeney Ballroom A-B Speaker 4 of 5 Nausica Arnoult, The Salk Institute for Biological Studies, USA Short Talk: Regulation of DNA Repair Pathway Choice in S/G2 by the NHEJ Inhibitor CYREN
Thursday, April 06 \| 5:00PM - 6:45PM Telomeres and Centromeres Room: Sweeney Ballroom A-B Speaker 5 of 5 Julia Promisel Cooper, NCI, National Institutes of Health, USA Telomeric Control of Kinetochore Assembly and Nuclear Envelope Breakdown
Thursday, April 06 \| 5:00PM - 6:45PM Finishing Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Homology search, strand exchange, dealing with DNA joint molecules. Speaker 1 of 5 * Maria Jasin, Memorial Sloan Kettering Cancer Center, USA
Thursday, April 06 \| 5:00PM - 6:45PM Finishing Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Homology search, strand exchange, dealing with DNA joint molecules. Speaker 2 of 5 Stephen C. Kowalczykowski, University of California, Davis, USA Molecular Functions and Single Molecule Studies of BRCA1, BRCA2, and RAD51 Paralogs
Thursday, April 06 \| 5:00PM - 6:45PM Finishing Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Homology search, strand exchange, dealing with DNA joint molecules. Speaker 3 of 5 Petr Cejka, Institute for Research in Biomedicine, Switzerland Processing of DNA Double-Strand Breaks for Repair by Homologous Recombination
Thursday, April 06 \| 5:00PM - 6:45PM Finishing Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Homology search, strand exchange, dealing with DNA joint molecules. Speaker 4 of 5 Ralph Scully, Beth Israel Deaconess Medical Center, USA Short Talk: Microhomology-Mediated Tandem Duplications form at Tus/Ter-Stalled Replication Forks in BRCA1 Mutant Cells
Thursday, April 06 \| 5:00PM - 6:45PM Finishing Recombination This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E Homology search, strand exchange, dealing with DNA joint molecules. Speaker 5 of 5 Stephen C. West, Francis Crick Institute, UK Unresolved Recombination Intermediates as a Source of DNA Breaks and Chromosome Aberration
Thursday, April 06 \| 6:45PM - 7:00PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Room: Sweeney Ballroom A-B
Thursday, April 06 \| 6:45PM - 7:00PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) This session is from DNA Repl & Recomb Room: Sweeney Ballroom C-E
Thursday, April 06 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney F, Main Level Breakouts No registration fees are used to fund alcohol served at this function.
Thursday, April 06 \| 8:00PM - 11:00PM Entertainment Room: Sweeney F Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
Thursday, April 06 \| 8:00PM - 11:00PM Cash Bar Room: Sweeney F, Main Level Breakouts
Friday, April 07 \| 10:25AM - 10:25AM Departure *Session Chair.