Web Desc
Angiogenesis and Vascular Disease
joint with Mitochondria, Metabolism and Heart
Organizer(s): Luisa Iruela-Arispe, Timothy T. Hla and Courtney Griffin
Date: May 08 - 12, 2017
Location: Eldorado Hotel & Spa, Santa Fe, NM, USA
Sponsored by Janssen R&D: Pharmaceutical Companies of Johnson & Johnson and Journal of Molecular Cell Biology (JMCB)
For important information on the coronavirus, please click here
Summary of Meeting:
Angiogenesis is critical to both the growth and repair of tissues as well as for the progression of several pathologies. Progress in our molecular understanding of vascular growth has facilitated the development of therapies that have been successfully applied in diseases such as retinopathy and cancer. Notwithstanding these advancements, much remains to be harnessed from the basic molecular mechanisms that control vascular growth. This conference will bring together leaders of research from basic science, translational science, biotechnology and pharmaceutical areas, to discuss progress in clinical and translational research areas. The goal of the conference is to highlight new discoveries, technological advances and therapeutic possibilities. Both established and up-and-coming investigators will have ample opportunities to interact informally and share views with junior investigators and trainees in a collegial and relaxed atmosphere. By promoting cross-disciplinary interactions, the meeting will enhance vascular biology research and applications to clinical medicine.
Scholarship Deadline: January 11 2017
Discounted Abstract Deadline: January 11 2017
Abstract Deadline: February 8 2017
Discounted Registration Deadline: March 8 2017
Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.


Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Janssen R&D: Pharmaceutical Companies of Johnson & JohnsonJournal of Molecular Cell Biology (JMCB)
We gratefully acknowledge additional support for this conference from:

Bio-Techne
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

EMBO Young Investigator Programme

Pfizer Research Technology Center
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
American Association for the Advancement of Science (AAAS)American Association for the Advancement of Science (AAAS)
We gratefully acknowledge the generous grant for this conference provided by:

National Heart, Lung, and Blood Institute (NHLBI)
Grant No. 1R13HL137302-01
Funding for this conference was made possible (in part) by HL137302-01 from the National Heart, Lung and Blood Institute. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the NIH; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Monday, May 08 | 4:00PM - 8:00PM
Arrival and Registration
Room: Eldorado Lounge


Monday, May 08 | 6:00PM - 8:00PM
Welcome Mixer
Room: Eldorado Lounge
No registration fees are used to fund alcohol served at this function.

Tuesday, May 09 | 7:30AM - 8:30AM
Breakfast
Room: Anasazi Ballroom


Tuesday, May 09 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Eldorado Grand Ballroom

Speaker 1 of 5
* Junichi Sadoshima, Rutgers New Jersey Medical School, USA

Tuesday, May 09 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Eldorado Grand Ballroom

Speaker 2 of 5
* Luisa Iruela-Arispe, University of California, Los Angeles, USA

Tuesday, May 09 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Eldorado Grand Ballroom

Speaker 3 of 5
Kari K. Alitalo, University of Helsinki, Finland
Therapeutic Potential of Vascular Growth Factors

Tuesday, May 09 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Eldorado Grand Ballroom

Speaker 4 of 5
David C. Chan, California Institute of Technology, USA
Mitochondria Dynamics

Tuesday, May 09 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Eldorado Grand Ballroom


Coffee Break

Tuesday, May 09 | 10:20AM - 12:30PM
Metabolism and Disease (Joint)
Room: Eldorado Grand Ballroom

Speaker 1 of 5
Robert E. Gerszten, Beth Israel Deaconess Medical Center, USA
Metabolic Profiles and the Risk of Cardiometabolic Diseases

Tuesday, May 09 | 10:20AM - 12:30PM
Metabolism and Disease (Joint)
Room: Eldorado Grand Ballroom

Speaker 2 of 5
* Andrew G. Dillin, University of California, Berkeley, USA
Mitochondria Mitokines and Aging

Tuesday, May 09 | 10:20AM - 12:30PM
Metabolism and Disease (Joint)
Room: Eldorado Grand Ballroom

Speaker 3 of 5
Peter F. Carmeliet, University of Leuven, VIB, Belgium
Angiogenesis Revisited: Role and (Therapeutic) Implications of Endothelial Metabolism

Tuesday, May 09 | 10:20AM - 12:30PM
Metabolism and Disease (Joint)
Room: Eldorado Grand Ballroom

Speaker 4 of 5
Arpita Chowdhury, Universitätsmedizin Göttingen, Germany
Short Talk: Oxidative Stress and Altered Mitochondrial Signaling in Barth Syndrome Models

Tuesday, May 09 | 10:20AM - 12:30PM
Metabolism and Disease (Joint)
Room: Eldorado Grand Ballroom

Speaker 5 of 5
Nicholas Sibinga, Albert Einstein College of Medicine, USA
Short Talk: Control of Mitochondrial Function by Atypical Cadherins

Tuesday, May 09 | 12:30PM - 5:00PM
On Own for Lunch


Tuesday, May 09 | 12:30PM - 1:00PM
Poster Setup
Room: Anasazi Ballroom


Tuesday, May 09 | 1:00PM - 10:00PM
Poster Viewing
Room: Anasazi Ballroom


Tuesday, May 09 | 2:30PM - 4:30PM
Workshop 1: Current Strategies for Funding Angiogenesis and
Vascular Disease Research
Room: Eldorado A

Speaker 1 of 6
* Luisa Iruela-Arispe, University of California, Los Angeles, USA

Tuesday, May 09 | 2:30PM - 4:30PM
Workshop 1: Current Strategies for Funding Angiogenesis and
Vascular Disease Research
Room: Eldorado A

Speaker 2 of 6
Yunling Gao, NHLBI, National Institutes of Health, USA
Angiogenesis Research: The Extramural Portfolio Supported by the National Heart, Lung, and Blood Institute, 2008-2015

Tuesday, May 09 | 2:30PM - 4:30PM
Workshop 1: Current Strategies for Funding Angiogenesis and
Vascular Disease Research
Room: Eldorado A

Speaker 3 of 6
Morris J. Birnbaum, Pfizer Inc., USA

Tuesday, May 09 | 2:30PM - 4:30PM
Workshop 1: Current Strategies for Funding Angiogenesis and
Vascular Disease Research
Room: Eldorado A

Speaker 4 of 6
Philip Tagari, Amgen, Inc., USA
Amgen – Funding External Innovation

Tuesday, May 09 | 2:30PM - 4:30PM
Workshop 1: Current Strategies for Funding Angiogenesis and
Vascular Disease Research
Room: Eldorado A

Speaker 5 of 6
Courtney Griffin, Oklahoma Medical Research Foundation, USA
Updates on the American Heart Association Research Funding Portfolio

Tuesday, May 09 | 2:30PM - 4:30PM
Workshop 1: Current Strategies for Funding Angiogenesis and
Vascular Disease Research
Room: Eldorado A

Speaker 6 of 6
Christer Betsholtz, Uppsala University, Sweden

Tuesday, May 09 | 2:30PM - 4:30PM
Workshop 1: How to Evaluate Metabolism in the Heart: From th
e Langendorff Perfusion to Metabolome Analyses
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 1 of 7
* Toren Finkel, University of Pittsburgh, UPMC, USA


Tuesday, May 09 | 2:30PM - 4:30PM
Workshop 1: How to Evaluate Metabolism in the Heart: From th
e Langendorff Perfusion to Metabolome Analyses
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 2 of 7
Larissa Pfisterer, Boehringer Ingelheim Pharma GmbH & Co KG, Germany
Regulation of Endothelial Cell Metabolism by Long Noncoding RNA lncflow2


Tuesday, May 09 | 2:30PM - 4:30PM
Workshop 1: How to Evaluate Metabolism in the Heart: From th
e Langendorff Perfusion to Metabolome Analyses
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 3 of 7
Jessica M. Pfleger, Temple University, USA
Bioenergetics as a Tool for Assessing Cardiomyocyte Response to ß–Adrenergic Stimulation and Insulin Resistance


Tuesday, May 09 | 2:30PM - 4:30PM
Workshop 1: How to Evaluate Metabolism in the Heart: From th
e Langendorff Perfusion to Metabolome Analyses
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 4 of 7
Paul T. Schumacker, Northwestern University, USA
Mitochondrial Complexes I and III Regulate Cardiomyocyte Proliferation in Adult Mouse Hearts


Tuesday, May 09 | 2:30PM - 4:30PM
Workshop 1: How to Evaluate Metabolism in the Heart: From th
e Langendorff Perfusion to Metabolome Analyses
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 5 of 7
Junco Shibayama Warren, University of Utah, USA
The Histone Methyltransferase Smyd1 Regulates Mitochondrial Energetics in Cardiomyocytes


Tuesday, May 09 | 2:30PM - 4:30PM
Workshop 1: How to Evaluate Metabolism in the Heart: From th
e Langendorff Perfusion to Metabolome Analyses
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 6 of 7
Yuan Zhang, University of Iowa, USA
Ketogenic Diet Rescues Cardiac Hypertrophy and Heart Failure Induced by Loss of the Mitochondrial Pyruvate Carrier 1


Tuesday, May 09 | 2:30PM - 4:30PM
Workshop 1: How to Evaluate Metabolism in the Heart: From th
e Langendorff Perfusion to Metabolome Analyses
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 7 of 7
Dan Shao, University of Washington, USA
Glucose Promotes Cell Growth by Suppressing Branched-Chain Amino Acid Degradation


Tuesday, May 09 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Tuesday, May 09 | 5:00PM - 7:00PM
Metabolite Signaling in Angiogenesis and Vascular Disease
Room: Eldorado A

Speaker 1 of 5
* William C. Sessa, Yale University School of Medicine, USA

Tuesday, May 09 | 5:00PM - 7:00PM
Metabolite Signaling in Angiogenesis and Vascular Disease
Room: Eldorado A

Speaker 2 of 5
Morris J. Birnbaum, Pfizer Inc., USA
Control of Hepatic Lipid Metabolism

Tuesday, May 09 | 5:00PM - 7:00PM
Metabolite Signaling in Angiogenesis and Vascular Disease
Room: Eldorado A

Speaker 3 of 5
Christer Betsholtz, Uppsala University, Sweden
Pericytes as Regulators of Vascular Stability

Tuesday, May 09 | 5:00PM - 7:00PM
Metabolite Signaling in Angiogenesis and Vascular Disease
Room: Eldorado A

Speaker 4 of 5
J. David Symons, University of Utah, USA
Short Talk: Endothelial Cell Autophagy Maintains Shear-Stress-Induced Nitric Oxide Generation via Glycolysis-Dependent Purinergic Signaling to eNOS

Tuesday, May 09 | 5:00PM - 7:00PM
Metabolite Signaling in Angiogenesis and Vascular Disease
Room: Eldorado A

Speaker 5 of 5
Andreas M. Beyer, Medical College of Wisconsin, USA
Short Talk: Autophagy is a Novel Regulatory Mechanism in the Human Microcirculation

Tuesday, May 09 | 5:00PM - 7:00PM
Mitochondria Quality Control
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 1 of 4
Gerald W. Dorn, II, Washington University School of Medicine, USA
The Cardiomyopathy of Defective Mitochondrial Fusion


Tuesday, May 09 | 5:00PM - 7:00PM
Mitochondria Quality Control
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 2 of 4
* Junichi Sadoshima, Rutgers New Jersey Medical School, USA
Mitophagy in the Heart


Tuesday, May 09 | 5:00PM - 7:00PM
Mitochondria Quality Control
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 3 of 4
R. Luke Wiseman, The Scripps Research Institute, USA
Stress-Responsive Regulation of Mitochondria Inner Membrane Proteostasis


Tuesday, May 09 | 5:00PM - 7:00PM
Mitochondria Quality Control
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 4 of 4
Ana Victoria Lechuga Vieco, Spanish National Center for Cardiovascular Research, Spain
Short Talk: Conflict between Mitochondrial DNA Variants


Tuesday, May 09 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Anasazi Ballroom
No registration fees are used to fund alcohol served at this function.

Tuesday, May 09 | 7:30PM - 10:00PM
Poster Session 1
Room: Anasazi Ballroom


Wednesday, May 10 | 7:30AM - 8:30AM
Breakfast
Room: Anasazi Ballroom


Wednesday, May 10 | 8:30AM - 11:45AM
Transcriptional Control of Endothelial Fate
Room: Eldorado A

Speaker 1 of 8
* Courtney Griffin, Oklahoma Medical Research Foundation, USA

Wednesday, May 10 | 8:30AM - 11:45AM
Transcriptional Control of Endothelial Fate
Room: Eldorado A

Speaker 2 of 8
William T. Pu, Children's Hospital, Harvard Medical School, USA
Transcriptional and Epigenetic Regulation of Endothelial Gene Expression


Wednesday, May 10 | 8:30AM - 11:45AM
Transcriptional Control of Endothelial Fate
Room: Eldorado A

Speaker 3 of 8
Michael Potente, Max Planck Institute for Heart and Lung Research, Germany
EMBO Young Investigator Lecture: Metabolism, Metabolites and Endothelial Plasticity

Wednesday, May 10 | 8:30AM - 11:45AM
Transcriptional Control of Endothelial Fate
Room: Eldorado A


Coffee Break

Wednesday, May 10 | 8:30AM - 11:45AM
Transcriptional Control of Endothelial Fate
Room: Eldorado A

Speaker 5 of 8
Brian L. Black, University of California, San Francisco, USA
Identification of Injury- and Regeneration-Responsive Cardiac Endothelium Enhancer Elements

Wednesday, May 10 | 8:30AM - 11:45AM
Transcriptional Control of Endothelial Fate
Room: Eldorado A

Speaker 6 of 8
William C. Sessa, Yale University School of Medicine, USA
New Insights into Endothelial Lipid Metabolism

Wednesday, May 10 | 8:30AM - 11:45AM
Transcriptional Control of Endothelial Fate
Room: Eldorado A

Speaker 7 of 8
Manu Beerens, Brigham and Women's Hospital, Harvard Medical School, USA
Short Talk: Prdm16 Modifies the Canonical Notch Output to Establish Proper Arterial Development

Wednesday, May 10 | 8:30AM - 11:45AM
Transcriptional Control of Endothelial Fate
Room: Eldorado A

Speaker 8 of 8
Akiko Mammoto, Medical College of Wisconsin, USA
Short Talk: YAP1 in Angiogenesis and Lung Regeneration

Wednesday, May 10 | 8:30AM - 11:45AM
Autophagy and Metabolism
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 1 of 7
Heidi M. McBride, McGill University, Canada
Emerging Functions of Mitochondrial-Derived Vesicles in Health and Disease.


Wednesday, May 10 | 8:30AM - 11:45AM
Autophagy and Metabolism
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 2 of 7
* Ana Maria Cuervo, Albert Einstein College of Medicine, USA
Control of Metabolism by Chaperone-Mediated Autophagy


Wednesday, May 10 | 8:30AM - 11:45AM
Autophagy and Metabolism
This session is from Mito, Metabolism and Heart
Room: Eldorado B


Coffee Break


Wednesday, May 10 | 8:30AM - 11:45AM
Autophagy and Metabolism
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 4 of 7
Daniel P. Kelly, University of Pennsylvania, USA
Mitochondrial Remodeling in the Developing and Diseased Heart


Wednesday, May 10 | 8:30AM - 11:45AM
Autophagy and Metabolism
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 5 of 7
E. Dale Abel, University of Iowa, Carver College of Medicine, USA
Myocardial Autophagy and Metabolic Regulation


Wednesday, May 10 | 8:30AM - 11:45AM
Autophagy and Metabolism
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 6 of 7
Helena C. Kenny, University of Iowa, USA
Short Talk: Inducible Deletion of OPA1 Causes Heart Failure in Part by mTOR - Mediated Suppression of Autophagy


Wednesday, May 10 | 8:30AM - 11:45AM
Autophagy and Metabolism
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 7 of 7
Iain Scott, University of Pittsburgh, USA
Short Talk: Acetylation of Mitochondrial Proteins by Gcn5l1 Promotes Enhanced Fatty Acid Oxidation in the Heart


Wednesday, May 10 | 11:45AM - 5:00PM
On Own for Lunch


Wednesday, May 10 | 11:45AM - 1:00PM
Poster Setup
Room: Anasazi Ballroom


Wednesday, May 10 | 1:00PM - 10:00PM
Poster Viewing
Room: Anasazi Ballroom


Wednesday, May 10 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Wednesday, May 10 | 5:00PM - 7:00PM
Epigenetic Regulation of Vascular Growth
Room: Eldorado A

Speaker 1 of 5
* Brian L. Black, University of California, San Francisco, USA

Wednesday, May 10 | 5:00PM - 7:00PM
Epigenetic Regulation of Vascular Growth
Room: Eldorado A

Speaker 2 of 5
Stefanie Dimmeler, University of Frankfurt, Germany
Function of Long Noncoding RNAs in the Regulation of the Vasculature

Wednesday, May 10 | 5:00PM - 7:00PM
Epigenetic Regulation of Vascular Growth
Room: Eldorado A

Speaker 3 of 5
Philip Tagari, Amgen, Inc., USA
Pharmacological and Genetic Inhibition of Hypoxia-Inducible Factor Prolyl Hydroxylases

Wednesday, May 10 | 5:00PM - 7:00PM
Epigenetic Regulation of Vascular Growth
Room: Eldorado A

Speaker 4 of 5
Courtney Griffin, Oklahoma Medical Research Foundation, USA
Chromatin Remodeling and Vascular Development

Wednesday, May 10 | 5:00PM - 7:00PM
Epigenetic Regulation of Vascular Growth
Room: Eldorado A

Speaker 5 of 5
Federico Bussolino, University of Torino, Italy
Short Talk: Transcription Factor EB Regulates VEGFR2 Function

Wednesday, May 10 | 5:00PM - 7:00PM
Cell Signaling and Metabolism
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 1 of 4
Pinchas Cohen, University of Southern California, USA
Mitochondrial-Derived Peptides and their Role in Vascular Disease


Wednesday, May 10 | 5:00PM - 7:00PM
Cell Signaling and Metabolism
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 2 of 4
Xiang-Dong Fu, University of California, San Diego, USA
A Novel Strategy to Inhibit Angiogenesis in Cancer


Wednesday, May 10 | 5:00PM - 7:00PM
Cell Signaling and Metabolism
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 3 of 4
Arieh Moussaieff, Hebrew University of Jerusalem, Israel
The Metabolic Switch of Cells Exiting Pluripotency


Wednesday, May 10 | 5:00PM - 7:00PM
Cell Signaling and Metabolism
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 4 of 4
* Lorrie A. Kirshenbaum, University of Manitoba, Canada
Short Talk: Alternative Spliced Form of Bnip3 Preferentially Interacts with Mitofusion2 and Endoplasmic Reticulum for Cell Survival


Wednesday, May 10 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Anasazi Ballroom
No registration fees are used to fund alcohol served at this function.

Wednesday, May 10 | 7:30PM - 10:00PM
Poster Session 2
Room: Anasazi Ballroom


Thursday, May 11 | 7:30AM - 8:30AM
Breakfast
Room: Anasazi Ballroom


Thursday, May 11 | 8:30AM - 11:45AM
Hypoxia Sensing Mechanism and Mitophagy (Joint)
Room: Eldorado Grand Ballroom

Speaker 1 of 8
* Stefanie Dimmeler, University of Frankfurt, Germany

Thursday, May 11 | 8:30AM - 11:45AM
Hypoxia Sensing Mechanism and Mitophagy (Joint)
Room: Eldorado Grand Ballroom

Speaker 2 of 8
Åsa B. Gustafsson, University of California, San Diego, USA
Parkin-Dependent Degradation of Mitochondria by a Rab5 Endosomal Pathway


Thursday, May 11 | 8:30AM - 11:45AM
Hypoxia Sensing Mechanism and Mitophagy (Joint)
Room: Eldorado Grand Ballroom

Speaker 3 of 8
* Kenneth Walsh, University of Virginia School of Medicine, USA
Clonal Hematopoiesis and Cardio-metabolic Disease: New Mechanisms, New Therapeutic Opportunities

Thursday, May 11 | 8:30AM - 11:45AM
Hypoxia Sensing Mechanism and Mitophagy (Joint)
Room: Eldorado Grand Ballroom


Coffee Break

Thursday, May 11 | 8:30AM - 11:45AM
Hypoxia Sensing Mechanism and Mitophagy (Joint)
Room: Eldorado Grand Ballroom

Speaker 5 of 8
Marlene Rabinovitch, Stanford University, USA
A BMP-Notch Axis Coordinates Mitochondrial Function, Chromatin Remodeling and Gene Regulation to Regenerate Endothelium in Response to Injury

Thursday, May 11 | 8:30AM - 11:45AM
Hypoxia Sensing Mechanism and Mitophagy (Joint)
Room: Eldorado Grand Ballroom

Speaker 6 of 8
M. Celeste Simon, University of Pennsylvania, USA
Balancing Cell Growth with Homeostasis in the Tumor Microenvironment

Thursday, May 11 | 8:30AM - 11:45AM
Hypoxia Sensing Mechanism and Mitophagy (Joint)
Room: Eldorado Grand Ballroom

Speaker 7 of 8
Ivan Menendez-Montes, Fundacion CNIC, Spain
Short Talk: Cardiac HIF/VHL Signaling Regulates Glycolytic and Oxidative Metabolic Programs and Is Essential for Myocardial Maturation during Heart Development

Thursday, May 11 | 8:30AM - 11:45AM
Hypoxia Sensing Mechanism and Mitophagy (Joint)
Room: Eldorado Grand Ballroom

Speaker 8 of 8
Erin Reineke, Houston Methodist Research Institute, USA
Short Talk: Coordination of Cellular Function by Steroid-Receptor Coactivator 2 in Stress-Induced Cardiac Angiogenesis

Thursday, May 11 | 11:45AM - 5:00PM
On Own for Lunch


Thursday, May 11 | 11:45AM - 1:00PM
Poster Setup
Room: Anasazi Ballroom


Thursday, May 11 | 1:00PM - 10:00PM
Poster Viewing
Room: Anasazi Ballroom


Thursday, May 11 | 2:30PM - 4:30PM
Workshop 2: Intracellular Signaling and Vascular Function
Room: Eldorado A

Speaker 1 of 6
* George E. Davis, University of Missouri School of Medicine, USA

Thursday, May 11 | 2:30PM - 4:30PM
Workshop 2: Intracellular Signaling and Vascular Function
Room: Eldorado A

Speaker 2 of 6
Christopher D. Kontos, Duke University Medical Center, USA
Caskin2: A Novel Regulator of Endothelial Cell Quiescence

Thursday, May 11 | 2:30PM - 4:30PM
Workshop 2: Intracellular Signaling and Vascular Function
Room: Eldorado A

Speaker 3 of 6
Qing Robert Miao, Medical College of Wisconsin, USA
Ras Signaling Is Required for Preventing Cerebrovascular Malformation

Thursday, May 11 | 2:30PM - 4:30PM
Workshop 2: Intracellular Signaling and Vascular Function
Room: Eldorado A

Speaker 4 of 6
Sarah J. Parker, Cedars Sinai Medical Center, USA
Proteomics Reveals Context-Dependent Shifts in Mitochondrial Protein Expression and Novel Non-Canonical TGFß Signaling Activation in the Aorta of Marfan Syndrome Mice

Thursday, May 11 | 2:30PM - 4:30PM
Workshop 2: Intracellular Signaling and Vascular Function
Room: Eldorado A

Speaker 5 of 6
Vivek Venkataramani, University Medical Center Göttingen, Germany
CD31 Expression Determines Redox Status and Chemoresistance in Human Angiosarcomas

Thursday, May 11 | 2:30PM - 4:30PM
Workshop 2: Intracellular Signaling and Vascular Function
Room: Eldorado A

Speaker 6 of 6
Ruowen Ge, National University of Singapore, Singapore
Extracellular Antiangiogenic Proteins Target Mitochondria through a Novel Route of Protein Trafficking via Endocytosis and Direct Endosome-Mitochondrion Fusion

Thursday, May 11 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Thursday, May 11 | 5:00PM - 7:00PM
Vascular Stability and Cell-Cell Interactions
Room: Eldorado A

Speaker 1 of 5
* Ralf H. Adams, Max Planck Institute for Molecular Biomedicine, Germany

Thursday, May 11 | 5:00PM - 7:00PM
Vascular Stability and Cell-Cell Interactions
Room: Eldorado A

Speaker 2 of 5
Harry (Hal) C. Dietz, Johns Hopkins University School of Medicine, Blade Therapeutics, USA
TGFbeta in Inherited Vasculopathies: A Matter of Aneurysmic Proportions

Thursday, May 11 | 5:00PM - 7:00PM
Vascular Stability and Cell-Cell Interactions
Room: Eldorado A

Speaker 3 of 5
George E. Davis, University of Missouri School of Medicine, USA
Molecular Determinants Governing EC-Pericyte Tube Co-Assembly and Stability

Thursday, May 11 | 5:00PM - 7:00PM
Vascular Stability and Cell-Cell Interactions
Room: Eldorado A

Speaker 4 of 5
Luisa Iruela-Arispe, University of California, Los Angeles, USA
Vascular Stability and Cell-Cell Interactions during Endothelial Regeneration

Thursday, May 11 | 5:00PM - 7:00PM
Vascular Stability and Cell-Cell Interactions
Room: Eldorado A

Speaker 5 of 5
Arie Horowitz, USA
Short Talk: Dynamic Equilibrium of Endothelial Cell Junctions Is Required for Vascular Morphogenesis


Thursday, May 11 | 5:00PM - 7:00PM
Metabolic Regulation of Cell Signaling
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 1 of 4
* Guido Kroemer, Cordeliers Research Center, France
Metabolic Regulation of Autophagy


Thursday, May 11 | 5:00PM - 7:00PM
Metabolic Regulation of Cell Signaling
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 2 of 4
Michael N. Sack, NHLBI, National Institutes of Health, USA
Nutrient Sensing, Mitochondria and the Inflammasome


Thursday, May 11 | 5:00PM - 7:00PM
Metabolic Regulation of Cell Signaling
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 3 of 4
Stephen Y. Chan, University of Pittsburgh School of Medicine, USA
The Emerging Nexus between Matrix Stiffness and Cellular Metabolism in the Diseased Pulmonary Vasculature: New Targets for Treating Pulmonary Hypertension


Thursday, May 11 | 5:00PM - 7:00PM
Metabolic Regulation of Cell Signaling
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 4 of 4
Jianhua Xiong, NHLBI, National Institutes of Health, USA
Short Talk: Fatty Acid Oxidation Regulates Endothelial Cell Fate


Thursday, May 11 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Anasazi Ballroom
No registration fees are used to fund alcohol served at this function.

Thursday, May 11 | 7:30PM - 10:00PM
Poster Session 3
Room: Anasazi Ballroom


Friday, May 12 | 7:30AM - 8:30AM
Breakfast
Room: Anasazi Ballroom


Friday, May 12 | 8:30AM - 11:45AM
Organ Specific Vasculature
Room: Eldorado A

Speaker 1 of 8
* Kathleen M. Caron, University of North Carolina at Chapel Hill, USA

Friday, May 12 | 8:30AM - 11:45AM
Organ Specific Vasculature
Room: Eldorado A

Speaker 2 of 8
Ralf H. Adams, Max Planck Institute for Molecular Biomedicine, Germany
Organ-Specific and Functional Specialization of Blood Vessels

Friday, May 12 | 8:30AM - 11:45AM
Organ Specific Vasculature
Room: Eldorado A

Speaker 3 of 8
Susan Quaggin, Northwestern University, USA
Unique Molecular and Functional Requirements of the Renal Vasculature

Friday, May 12 | 8:30AM - 11:45AM
Organ Specific Vasculature
Room: Eldorado A


Coffee Break

Friday, May 12 | 8:30AM - 11:45AM
Organ Specific Vasculature
Room: Eldorado A

Speaker 5 of 8
Anne C. Eichmann, Yale University School of Medicine, USA
Cross-Talk between Vessels and Nerves

Friday, May 12 | 8:30AM - 11:45AM
Organ Specific Vasculature
Room: Eldorado A

Speaker 6 of 8
Paul S. Frenette, Albert Einstein College of Medicine, USA
Bone Marrow Vascular Niche

Friday, May 12 | 8:30AM - 11:45AM
Organ Specific Vasculature
Room: Eldorado A

Speaker 7 of 8
Lisandra Vila Ellis, MD Anderson Cancer Center, USA
Short Talk: Investigating Alveolar Angiogenesis in the Developing Mouse Lung

Friday, May 12 | 8:30AM - 11:45AM
Organ Specific Vasculature
Room: Eldorado A

Speaker 8 of 8
Ching-Ling Ellen Lien, Saban Research Institute, Children's Hospital, USA
Short Talk: Coordinated Development of Coronary Vessels, Cortical Cardiomyocytes and Cardiac Lymphatics Supports Heart Morphogenesis and Regeneration

Friday, May 12 | 8:30AM - 11:45AM
Regulation of mPTP Opening
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 1 of 7
Toren Finkel, University of Pittsburgh, UPMC, USA
Mouse Models of the Mitochondrial Calcium Uniporter Complex


Friday, May 12 | 8:30AM - 11:45AM
Regulation of mPTP Opening
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 2 of 7
Elizabeth A. Jonas, Yale University, USA
The Mitochondrial Permeability Transition Pore: Molecular Structure and Function in Health and Disease


Friday, May 12 | 8:30AM - 11:45AM
Regulation of mPTP Opening
This session is from Mito, Metabolism and Heart
Room: Eldorado B


Coffee Break


Friday, May 12 | 8:30AM - 11:45AM
Regulation of mPTP Opening
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 4 of 7
John W. Elrod, Lewis Katz School of Medicine at Temple University, USA
Mitochondrial Calcium Exchange in Heart Disease


Friday, May 12 | 8:30AM - 11:45AM
Regulation of mPTP Opening
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 5 of 7
* Jeffery D. Molkentin, Cincinnati Children's Hospital Medical Center, USA
Mitochondrial Calcium Regulated by MCU Underlies Skeletal Muscle Adaptation


Friday, May 12 | 8:30AM - 11:45AM
Regulation of mPTP Opening
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 6 of 7
Amit U. Joshi, Stanford University SOM, USA
Short Talk: Mitochondrial Dynamics in Neurodegeneration in Patient-Derived Cells and in Animal Models


Friday, May 12 | 8:30AM - 11:45AM
Regulation of mPTP Opening
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 7 of 7
Vivian W. Moraes, The Scripps Research Institute, USA
Short Talk: PERK Activation Regulates Mitochondrial Quality Control during Endoplasmic Reticulum Stress


Friday, May 12 | 11:45AM - 5:00PM
On Own for Lunch


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2: How to Evaluate Mitophagy and Mitochondrial Func
tion in the Cardiovascular System
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 1 of 7
* Åsa B. Gustafsson, University of California, San Diego, USA


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2: How to Evaluate Mitophagy and Mitochondrial Func
tion in the Cardiovascular System
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 2 of 7
Brian Glancy, NHLBI and NIAMS, National Institutes of Health, USA
The Mitochondrial Reticulum of the Heart


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2: How to Evaluate Mitophagy and Mitochondrial Func
tion in the Cardiovascular System
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 3 of 7
Knut Lauritzen, Oslo University Hospital, Norway
Impaired Dynamics and Function of Mitochondria Caused by mtDNA Damage Leads to Heart Failure


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2: How to Evaluate Mitophagy and Mitochondrial Func
tion in the Cardiovascular System
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 4 of 7
Xiyuan Lu, University of California, Davis, USA
Mitochondrial Subpopulations and Heterogeneity in Adult Cardiac Myocytes Revealed by Confocal Imaging


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2: How to Evaluate Mitophagy and Mitochondrial Func
tion in the Cardiovascular System
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 5 of 7
Liming Pei, Children's Hospital of Philadelphia/University of Pennsylvania, USA
A Heart-Derived Hormone that Regulates Body Growth


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2: How to Evaluate Mitophagy and Mitochondrial Func
tion in the Cardiovascular System
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 6 of 7
Venkatesh Sundararajan, Rutgers New Jersey Medical School, USA
Mitochondrial Lon Protease Protects the Heart in vivo Against Ischemia-Reperfusion Injury by Reducing Oxidative Damage


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2: How to Evaluate Mitophagy and Mitochondrial Func
tion in the Cardiovascular System
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 7 of 7
Nuo Sun, NHLBI, National Institutes of Health, USA
Measuring Cardiac Mitophagy and the Role of USP30 in Heart Failure


Friday, May 12 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Friday, May 12 | 5:00PM - 6:45PM
Lymphangiogenesis
Room: Eldorado A

Speaker 1 of 4
* Anne C. Eichmann, Yale University School of Medicine, USA

Friday, May 12 | 5:00PM - 6:45PM
Lymphangiogenesis
Room: Eldorado A

Speaker 2 of 4
Tsutomu Kume, Northwestern University, USA
Regulation of Postnatal Lymphatic Vessel Development by Foxc1 and Foxc2

Friday, May 12 | 5:00PM - 6:45PM
Lymphangiogenesis
Room: Eldorado A

Speaker 3 of 4
Tatiana V. Petrova, CHUV, University of Lausanne, Switzerland
Mechanisms of Lymphatic Vessel Specialization

Friday, May 12 | 5:00PM - 6:45PM
Lymphangiogenesis
Room: Eldorado A

Speaker 4 of 4
Kathleen M. Caron, University of North Carolina at Chapel Hill, USA
Lymphatics in Myocardial Injury and Repair

Friday, May 12 | 5:00PM - 7:00PM
Metabolism and Heart Failure
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 1 of 4
* Richard N. Kitsis, Albert Einstein College of Medicine, USA
Chaperone-Mediated Autophagy in the Regulation of Mitochondrial Function and Heart Failure


Friday, May 12 | 5:00PM - 7:00PM
Metabolism and Heart Failure
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 2 of 4
Rong Tian, University of Washington, USA
The Signaling Role of Branched Chain Amino Acids


Friday, May 12 | 5:00PM - 7:00PM
Metabolism and Heart Failure
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 3 of 4
Stephen L. Archer, Queen's University, Canada
Role of Acquired Abnormalities in Mitochondrial Dynamics and the Mitochondrial Calcium Uniporter (MCU) in Pulmonary Hypertension


Friday, May 12 | 5:00PM - 7:00PM
Metabolism and Heart Failure
This session is from Mito, Metabolism and Heart
Room: Eldorado B

Speaker 4 of 4
Katsuhito Fujiu, University of Tokyo, Japan
Short Talk: Cardiac Macrophage Is Required to Avoid Heart Failure and Cardiac Sudden Death after Pressure Overload


Friday, May 12 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Eldorado A


Friday, May 12 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
This session is from Mito, Metabolism and Heart
Room: Eldorado B


Friday, May 12 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Anasazi Ballroom
No registration fees are used to fund alcohol served at this function.

Friday, May 12 | 8:00PM - 11:00PM
Entertainment
Room: Anasazi Ballroom
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Friday, May 12 | 8:00PM - 11:00PM
Cash Bar
Room: Anasazi Ballroom


Saturday, May 13 | 10:24AM - 10:24AM
Departure


*Session Chair
†Invited, not yet responded.