Web Desc
Neuronal Control of Appetite, Metabolism and Weight
joint with Gastrointestinal Control of Metabolism
Organizer(s): Lora K. Heisler and Scott M. Sternson
Date: May 09 - 13, 2017
Location: Tivoli Hotel and Congress Center, Copenhagen, Denmark
Lead Sponsor: Novo Nordisk A/S. Sponsored by Arena Pharmaceuticals, Inc.
Summary of Meeting:
Obesity, a condition that is becoming a leading cause of human morbidity and mortality, is among the global healthcare challenges of the 21st century. Obesity is primarily a result of the cumulative effect of increased food intake beyond the body’s energetic requirements over time. Emerging research reveals critical integrative neuronal systems that control both energy and glucose homeostasis, which have encouraging implications for the future treatment of obesity. This symposium will fuse existing knowledge with the latest discoveries in the neural circuits underpinning nutrient sensation, satiety, food reward, developmental programming and glucoregulatory function. Furthermore, recent findings will be presented on the peripheral regulation of these neural circuits by gut and adipocyte-derived signals. The application of cutting-edge neuroscience approaches and the clinical relevance of basic science discoveries to obesity research will also be highlighted. Recent advances in emerging treatment options will be discussed, including surgical interventions and next-generation pharmacotherapies. In combination with a joint symposium on the” Gastrointestinal Control of Metabolism,” this exciting program will bring together breaking research from both basic science and translational realms on the etiology and treatment of obesity and type 2 diabetes.
Scholarship Deadline: January 12 2017
Discounted Abstract Deadline: January 12 2017
Abstract Deadline: February 9 2017
Discounted Registration Deadline: March 9 2017
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Arena Pharmaceuticals, Inc.
We gratefully acknowledge additional support for this conference from:
Research Diets, Inc.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Novo Nordisk A/S
Keystone Symposia thanks our Lead Sponsor for generously supporting this meeting:
Novo Nordisk A/S
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Molecular Metabolism (Elsevier GmbH)NeuroscientistNews
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Tuesday, May 09 | 4:00PM - 8:00PM
Arrival and Registration
Room: Foyer


Tuesday, May 09 | 6:00PM - 8:00PM
Welcome Mixer
Room: Brasserie 3
No registration fees are used to fund alcohol served at this function.

Wednesday, May 10 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Wednesday, May 10 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Tivoli Congress Hall

Speaker 1 of 5
* Lora K. Heisler, Rowett Institute, University of Aberdeen, UK

Wednesday, May 10 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Tivoli Congress Hall

Speaker 2 of 5
* Randy J. Seeley, University of Michigan, USA

Wednesday, May 10 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Tivoli Congress Hall

Speaker 3 of 5
Stephen O'Rahilly, University of Cambridge, UK
Metabolic Disease: Lessons from Natural Human Variation

Wednesday, May 10 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Tivoli Congress Hall

Speaker 4 of 5
Klaus H. Kaestner, University of Pennsylvania School of Medicine, USA
The Intestinal Stem Cell Niche – At the Base of It All

Wednesday, May 10 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Tivoli Congress Hall


Coffee Break

Wednesday, May 10 | 10:20AM - 11:45AM
Nutrient Sensing and Gut Signaling (Joint)
Room: Tivoli Congress Hall

Speaker 1 of 5
* Andrew Butler, St. Louis University, USA

Wednesday, May 10 | 10:20AM - 11:45AM
Nutrient Sensing and Gut Signaling (Joint)
Room: Tivoli Congress Hall

Speaker 2 of 5
* Fiona M. Gribble, University of Cambridge, UK

Wednesday, May 10 | 10:20AM - 11:45AM
Nutrient Sensing and Gut Signaling (Joint)
Room: Tivoli Congress Hall

Speaker 3 of 5
Ronald M. Evans, HHMI/The Salk Institute, USA
Gut Feelings: Systemic Reach of Intestinal FXR

Wednesday, May 10 | 10:20AM - 11:45AM
Nutrient Sensing and Gut Signaling (Joint)
Room: Tivoli Congress Hall

Speaker 4 of 5
Kristina Schoonjans, École Polytechnique Fédérale de Lausanne – EPFL, Switzerland
Bile Acid Signaling in Metabolic Disease

Wednesday, May 10 | 10:20AM - 11:45AM
Nutrient Sensing and Gut Signaling (Joint)
Room: Tivoli Congress Hall

Speaker 5 of 5
Joshua Thaler, University of Washington, USA
Short Talk: Prevention of Microglial Inflammatory Signaling Reduces Susceptibility to Diet-Induced Obesity

Wednesday, May 10 | 11:45AM - 2:30PM
On Own for Lunch


Wednesday, May 10 | 11:45AM - 1:00PM
Poster Setup
Room: Vandsalen


Wednesday, May 10 | 1:00PM - 10:00PM
Poster Viewing
Room: Vandsalen


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 1 of 9
* Thomas Alexander Lutz, University of Zürich, Switzerland

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 2 of 9
* Petra Kotzbeck, Medical University of Graz, Austria

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 3 of 9
Yong Xu, Baylor College of Medicine, USA
5-HT Neurons and Eating Disorders

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 4 of 9
Manon Duquenne, INSERM Université Lille 2, France
A Role for Tanycyte Exocytosis in the Central Control of Energy Homeostasis?

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 5 of 9
Christian Stockmann, University of Zurich, Switzerland
The Role of Vascular Endothelial Growth Factor-A in the Context of Cancer Cachexia and Chemotherapy

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 6 of 9
Kevin G. Murphy, Imperial College London, UK
Investigating Disorders Associated with Weight Loss

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 7 of 9
Serge Luquet, Université Paris Diderot, France
Palatability Can Drive Feeding Independent of AgRP Neurons

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 8 of 9
Christin Kosse, Francis Crick Institute, UK
Functional Properties of GAD65 Neurons in the Lateral Hypothalamus

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 9 of 9
Yunlei Yang, SUNY Upstate Medical University, USA
Deciphering Anorexigenic Septohypothalamic Feeding Circuits

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 1 of 7
* Timo D. Müller, Institute for Diabetes and Obesity, Germany


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 2 of 7
Anne-Charlotte Jarry, Paris Diderot University, France
Neuromedin U Blocks Gastric Emptying through Vagal-Dependent Mechanisms and Improves Oral Glucose Tolerance


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 3 of 7
Geke Aline Boer, University of Copenhagen, Biomedical Institute, Denmark
Acute Reduction of GIP: Effects on Lipid and Bone Metabolism


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 4 of 7
Emily C. Bruggeman, University of Texas Southwestern Medical Center, USA
Ghrelin Receptor Deletion Increases Morbidity and Mortality in a Prader-Willi Syndrome Mouse Model


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 5 of 7
Natalia Petersen, University of Copenhagen, Denmark
'Tailoring' the Intestinal Epithelium for Type 2 Diabetes Treatment: Modulation of L-Cell Differentiation


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 6 of 7
Hai-Bin Ruan, University of Minnesota, USA
Diet- and Microbiota-Sensitive Intestinal O-GlcNAc Signaling Controls Enteroendocrine Cell Development and Function


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 7 of 7
Sara Lind Jepsen, University of Copenhagen, Denmark
Somatostatin Regulates GLP-1 Secretion through the Somatostatin Receptor Subtype 2


Wednesday, May 10 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Wednesday, May 10 | 5:00PM - 7:00PM
Interactions between Ingestive Signals and Reward Circuits
Room: Carstensen

Speaker 1 of 6
* Matt Carter, Williams College, USA

Wednesday, May 10 | 5:00PM - 7:00PM
Interactions between Ingestive Signals and Reward Circuits
Room: Carstensen

Speaker 2 of 6
* Agatha A. van der Klaauw, University of Cambridge, UK

Wednesday, May 10 | 5:00PM - 7:00PM
Interactions between Ingestive Signals and Reward Circuits
Room: Carstensen

Speaker 3 of 6
Michael A. Cowley, Monash University, Australia
Leptin Receptor Expressing Neurons of the Dorsomedial Hypothalamus Play a Limited Role in Regulating Food Intake but a Critical Role in Regulating Metabolism

Wednesday, May 10 | 5:00PM - 7:00PM
Interactions between Ingestive Signals and Reward Circuits
Room: Carstensen

Speaker 4 of 6
Suzanne Lee Dickson, Sahlgrenska Academy, Gothenburg University, Sweden
Brain Ghrelin Signaling and Food Reward Behavior

Wednesday, May 10 | 5:00PM - 7:00PM
Interactions between Ingestive Signals and Reward Circuits
Room: Carstensen

Speaker 5 of 6
Christian Lüscher, University of Geneva, Switzerland
Feeding Circuits that Can Override Metabolic Needs

Wednesday, May 10 | 5:00PM - 7:00PM
Interactions between Ingestive Signals and Reward Circuits
Room: Carstensen

Speaker 6 of 6
Claire J. Foldi, Monash University, Australia
Short Talk: CNS Reward Pathways in Anorexia Nervosa: Insights from a Rat Model

Wednesday, May 10 | 5:00PM - 7:00PM
Gut Bacteria as Cause and Treatment of Metabolic Diseases
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen
Gut bacteria as cause and treatment of metabolic diseases.
Speaker 1 of 5
* Gilles Mithieux, INSERM, France


Wednesday, May 10 | 5:00PM - 7:00PM
Gut Bacteria as Cause and Treatment of Metabolic Diseases
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen
Gut bacteria as cause and treatment of metabolic diseases.
Speaker 2 of 5
Fredrik Bäckhed, University of Gothenburg, Sweden
Microbial Signaling from the Gut and Resulting Effects on Host Metabolism


Wednesday, May 10 | 5:00PM - 7:00PM
Gut Bacteria as Cause and Treatment of Metabolic Diseases
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen
Gut bacteria as cause and treatment of metabolic diseases.
Speaker 3 of 5
Martin J. Blaser, New York University School of Medicine, USA
Effects of the Early Life Microbiota on the Development of Metabolic Illnesses


Wednesday, May 10 | 5:00PM - 7:00PM
Gut Bacteria as Cause and Treatment of Metabolic Diseases
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen
Gut bacteria as cause and treatment of metabolic diseases.
Speaker 4 of 5
Karine Clément, INSERM / Sorbonne Universite, France
Microbiome as Therapy


Wednesday, May 10 | 5:00PM - 7:00PM
Gut Bacteria as Cause and Treatment of Metabolic Diseases
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen
Gut bacteria as cause and treatment of metabolic diseases.
Speaker 5 of 5
Edna A. Trujillo, University of Wisconsin-Madison, USA
Short Talk: Metabolite Profiling of Plasma and Cecum Elucidates the Impacts of Host Genetics and Environment on the Gut Microbiota


Wednesday, May 10 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Vandsalen
No registration fees are used to fund alcohol served at this function.

Wednesday, May 10 | 7:30PM - 10:00PM
Poster Session 1
Room: Vandsalen


Thursday, May 11 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
Room: Tivoli Congress Hall

Speaker 1 of 9
* Qingchun Tong, University of Texas Medical School, USA

Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
Room: Tivoli Congress Hall

Speaker 2 of 9
* Matthew R. Hayes, University of Pennsylvania, USA

Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
Room: Tivoli Congress Hall

Speaker 3 of 9
Sabrina Diano, Yale University School of Medicine, USA
Mitochondrial Control of the Melanocortin System

Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
Room: Tivoli Congress Hall

Speaker 4 of 9
Martin G. Myers, Jr., University of Michigan, USA
LepRb Signaling and the Regulation of Transcription

Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
Room: Tivoli Congress Hall


Coffee Break

Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
Room: Tivoli Congress Hall

Speaker 6 of 9
Joseph T. Bass, Northwestern University, USA
Identification of an SCN-AgRP Circadian Neurocircuit Regulating Obesity and Systemic Metabolism


Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
Room: Tivoli Congress Hall

Speaker 7 of 9
Lori M. Zeltser, Columbia University, USA
Gene X Environment Interactions that Promote Anorexia-Like Behavior

Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
Room: Tivoli Congress Hall

Speaker 8 of 9
Ali Guler, University of Virginia, USA
Short Talk: Dopamine Signaling in the SCN Regulates Circadian Consumption of High-Fat Diet

Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
Room: Tivoli Congress Hall

Speaker 9 of 9
Mathias Treier, Max-Delbrueck-Center for Molecular Medicine, Germany
Short Talk: Identification of the Hypothalamic Circuit Maintaining Food Foraging

Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut-Pancreas Development I
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 1 of 8
* Praveen Sethupathy, Cornell University, USA


Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut-Pancreas Development I
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 2 of 8
Fiona M. Gribble, University of Cambridge, UK
The Biology of Enteroendocrine Cells


Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut-Pancreas Development I
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 3 of 8
Heiko Lickert, Institute of Diabetes and Regeneration, Germany
Dissecting Intestinal Stem Cell Lineage Decisions


Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut-Pancreas Development I
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen


Coffee Break


Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut-Pancreas Development I
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 5 of 8
James M. Wells, Cincinnati Children's Hospital Research Foundation, USA
Human Pluripotent Stem Cell-Derived Gastrointestinal Organoids as New Models to Study Metabolic and Digestive Diseases


Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut-Pancreas Development I
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 6 of 8
Lori Sussel, University of Colorado Anschutz Medical Campus, USA
Loss of Beta Cell Identity Related to Diabetes


Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut-Pancreas Development I
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 7 of 8
John Furness, University of Melbourne, Australia
Short Talk: Diversity of Enteroendocrine Cells between Species and Regions Studied at a Cellular and Subcellular Level


Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut-Pancreas Development I
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 8 of 8
Sandra Guilmeau, INSERM U1016 Institut Cochin, CNRS UMR 8104, France
Short Talk: Contribution of ChREBP in Intestinal GLP-1 Production


Thursday, May 11 | 11:45AM - 5:00PM
On Own for Lunch


Thursday, May 11 | 11:45AM - 1:00PM
Poster Setup
Room: Vandsalen


Thursday, May 11 | 1:00PM - 10:00PM
Poster Viewing
Room: Vandsalen


Thursday, May 11 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Thursday, May 11 | 5:00PM - 7:00PM
Signaling from Periphery to Brain to Modulate Energy Balance
(Joint)

Room: Tivoli Congress Hall

Speaker 1 of 6
* Suzanne M. Appleyard, Washington State University, USA

Thursday, May 11 | 5:00PM - 7:00PM
Signaling from Periphery to Brain to Modulate Energy Balance
(Joint)

Room: Tivoli Congress Hall

Speaker 2 of 6
* David Olson, University of Michigan, USA

Thursday, May 11 | 5:00PM - 7:00PM
Signaling from Periphery to Brain to Modulate Energy Balance
(Joint)

Room: Tivoli Congress Hall

Speaker 3 of 6
Jeffrey M. Friedman, Rockefeller University, USA
Neural Control of Food Intake, Locomotion and Glucose Metabolism

Thursday, May 11 | 5:00PM - 7:00PM
Signaling from Periphery to Brain to Modulate Energy Balance
(Joint)

Room: Tivoli Congress Hall

Speaker 4 of 6
Randy J. Seeley, University of Michigan, USA
How the Gut Regulates Metabolic Status

Thursday, May 11 | 5:00PM - 7:00PM
Signaling from Periphery to Brain to Modulate Energy Balance
(Joint)

Room: Tivoli Congress Hall

Speaker 5 of 6
Ivan E. de Araujo, Icahn School of Medicine at Mount Sinai, USA
What Does Sugar Do to the Brain? Circuit Logic for Sugar Sensing

Thursday, May 11 | 5:00PM - 7:00PM
Signaling from Periphery to Brain to Modulate Energy Balance
(Joint)

Room: Tivoli Congress Hall

Speaker 6 of 6
Celine E. Riera, Cedars-Sinai Medical Center, USA
Short Talk: The Sense of Smell Impacts Metabolic Health and Obesity

Thursday, May 11 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Tivoli Congress Hall
No registration fees are used to fund alcohol served at this function.

Thursday, May 11 | 7:30PM - 10:00PM
Poster Session 2
Room: Vandsalen


Friday, May 12 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
Room: Tivoli Congress Hall

Speaker 1 of 9
* Clemence Blouet, University of Cambridge, UK

Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
Room: Tivoli Congress Hall

Speaker 2 of 9
* J. Nicholas Betley, University of Pennsylvania, USA

Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
Room: Tivoli Congress Hall

Speaker 3 of 9
Scott M. Sternson, HHMI/Janelia Research Campus, USA
Motivational Mechanisms Controlling Hunger

Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
Room: Tivoli Congress Hall

Speaker 4 of 9
Garret D. Stuber, University of North Carolina at Chapel Hill School of Medicine, USA
Lateral Hypothalamic Circuits for Feeding and Reward


Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
Room: Tivoli Congress Hall


Coffee Break

Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
Room: Tivoli Congress Hall

Speaker 6 of 9
Tamas L. Horvath, Yale School of Medicine, USA
Appetite Circuits in the Regulation of Complex Behavior

Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
Room: Tivoli Congress Hall

Speaker 7 of 9
Roger D. Cone, University of Michigan, USA
Melanocortins: From Pharmacology to Pharmacotherapy


Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
Room: Tivoli Congress Hall

Speaker 8 of 9
Tatiana Korotkova, Max Planck Institute for Metabolism Research, Germany
Short Talk: Gamma Oscillations Organize Top-Down Signaling to Hypothalamus and Enable Food-Seeking

Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
Room: Tivoli Congress Hall

Speaker 9 of 9
Marcelo O. Dietrich, Yale University, USA
Short Talk: Behavioral Ontogeny of Hypothalamic Neurons

Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines - What Does the Future Hold?
This session is from GI Control of Metabolism

Room: Ballonsalen/Blomstersalen

Speaker 1 of 8
* Ruth E. Gimeno, Eli Lilly and Company, USA


Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines - What Does the Future Hold?
This session is from GI Control of Metabolism

Room: Ballonsalen/Blomstersalen

Speaker 2 of 8
Jens Juul Holst, University of Copenhagen the Panum Institute, Denmark
The Role of the Gut in the Development of Type 2 Diabetes


Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines - What Does the Future Hold?
This session is from GI Control of Metabolism

Room: Ballonsalen/Blomstersalen

Speaker 3 of 8
Tricia M. Tan, Imperial College London, UK
Triple Gut Hormones as Therapy


Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines - What Does the Future Hold?
This session is from GI Control of Metabolism

Room: Ballonsalen/Blomstersalen


Coffee Break


Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines - What Does the Future Hold?
This session is from GI Control of Metabolism

Room: Ballonsalen/Blomstersalen

Speaker 5 of 8
David E. Cummings, University of Washington, USA
Metabolic Surgery: Mechanisms and Use of “Bariatric” Operations to Treat Type 2 Diabetes


Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines - What Does the Future Hold?
This session is from GI Control of Metabolism

Room: Ballonsalen/Blomstersalen

Speaker 6 of 8
Niels Vrang, Gubra, Denmark
Short Talk: The Effect of FXR, PPAR-a/d and GLP-1 Agonism on Liver Disease in Diet-Induced Obese and Biopsy-Confirmed Mouse Models of NASH


Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines - What Does the Future Hold?
This session is from GI Control of Metabolism

Room: Ballonsalen/Blomstersalen

Speaker 7 of 8
Wendy M. McKimpson, Columbia University, USA
Short Talk: Foxo1-Expressing Cells in the Gut as a Source of Insulin for Diabetes Treatment


Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines - What Does the Future Hold?
This session is from GI Control of Metabolism

Room: Ballonsalen/Blomstersalen

Speaker 8 of 8
Makoto Fukuda, Baylor College of Medicine, USA
Short Talk: Gut Hormone GIP Drives Hypothalamic Pathogenesis of Obesity


Friday, May 12 | 11:45AM - 5:00PM
On Own for Lunch


Friday, May 12 | 11:45AM - 1:00PM
Poster Setup
Room: Vandsalen


Friday, May 12 | 1:00PM - 10:00PM
Poster Viewing
Room: Vandsalen


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 1 of 8
* Lene Jessen, Zealand Pharma, Denmark


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 2 of 8
Maria H. Hauge, Copenhagen University, Denmark
Gq and Gs Signaling Acting in Synergy to Control GLP-1 Secretion


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 3 of 8
Youngjung Kim, Icahn School of Medicine at Mount Sinai, USA
Pyruvate Kinase as a Novel Metabolic Regulator of Beta Cell Loss in Diabetes


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 4 of 8
Alyce M. Martin, Flinders University, Australia
Gut Serotonin Is a Signaling Nexus between the Gut Microbiome and Host Metabolism


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 5 of 8
Louise Olofsson, University of Gothenburg, Sweden
Role of the Gut Microbiota in Diet-Induced Hypothalamic Inflammation


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 6 of 8
Anette Christ, University of Massachusetts Medical School, USA
Long-Term Epigenetic Re-Programming of Myeloid Precursor Cells in a Hyperlipidemic Environment


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 7 of 8
Nadja Gebert, Leibniz Institute on Aging, Germany
Age and Diet Affect the Intestinal Crypt Proteome


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 8 of 8
Jonathan D. Douros, Duke University, USA
Increased Glucose-Dependent Insulinotropic Polypeptide (GIP) Secretion and Signaling Improves Beta-Cell Function following Vertical Sleeve Gastrectomy (VSG)


Friday, May 12 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Friday, May 12 | 5:00PM - 7:00PM
Cutting-Edge Approaches in Obesity Research
Room: Tivoli Congress Hall

Speaker 1 of 6
* Jeffrey M. Zigman, University of Texas Southwestern Medical Center, USA

Friday, May 12 | 5:00PM - 7:00PM
Cutting-Edge Approaches in Obesity Research
Room: Tivoli Congress Hall

Speaker 2 of 6
* Daniela Cota, Neurocentre Magendie, France

Friday, May 12 | 5:00PM - 7:00PM
Cutting-Edge Approaches in Obesity Research
Room: Tivoli Congress Hall

Speaker 3 of 6
Stephen Liberles, Harvard Medical School, USA
Molecular and Genetic Analysis of the Vagus Nerve

Friday, May 12 | 5:00PM - 7:00PM
Cutting-Edge Approaches in Obesity Research
Room: Tivoli Congress Hall

Speaker 4 of 6
Andres Lozano, University of Toronto, Toronto Western Hospital, Canada
Deep Brain Stimulation to Treat Obesity or Anorexia

Friday, May 12 | 5:00PM - 7:00PM
Cutting-Edge Approaches in Obesity Research
Room: Tivoli Congress Hall

Speaker 5 of 6
Kevin L. Grove, Novo Nordisk, USA
Obesity-Related Genes in the Rhesus Macaque

Friday, May 12 | 5:00PM - 7:00PM
Cutting-Edge Approaches in Obesity Research
Room: Tivoli Congress Hall

Speaker 6 of 6
John N. Campbell, University of Virginia, USA
Short Talk: A Molecular Census of Arcuate Hypothalamus and Median Eminence Cell Types


Friday, May 12 | 5:00PM - 7:00PM
Stem Cells, Gut-Pancreas Development II
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 1 of 5
* Lori Sussel, University of Colorado Anschutz Medical Campus, USA


Friday, May 12 | 5:00PM - 7:00PM
Stem Cells, Gut-Pancreas Development II
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 2 of 5
Andrew B. Leiter, University of Massachusetts Medical School, USA
Differentiation of Enteroendocrine Cells


Friday, May 12 | 5:00PM - 7:00PM
Stem Cells, Gut-Pancreas Development II
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 3 of 5
Praveen Sethupathy, Cornell University, USA
Microbiota, MicroRNAs, and Intestinal Stem Cell Function


Friday, May 12 | 5:00PM - 7:00PM
Stem Cells, Gut-Pancreas Development II
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 4 of 5
Susumu Seino, Kobe University Graduate School of Medicine, Japan
Beta-Cell Glutamate Signaling Is Critical for Incretin-Induced Insulin Secretion


Friday, May 12 | 5:00PM - 7:00PM
Stem Cells, Gut-Pancreas Development II
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 5 of 5
William L. Holland, University of Texas Southwestern Medical Center, USA
Short Talk: Glucagon Receptor Inhibition Restores Functional Beta Cell Mass and Reverses Hyperglycemia in Type-1 Diabetic Mice


Friday, May 12 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Tivoli Congress Hall
No registration fees are used to fund alcohol served at this function.

Friday, May 12 | 7:30PM - 10:00PM
Poster Session 3
Room: Vandsalen


Saturday, May 13 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Saturday, May 13 | 8:00AM - 8:30AM
Poster Setup
Room: Vandsalen


Saturday, May 13 | 8:30AM - 5:00PM
Poster Viewing
Room: Vandsalen


Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 1 of 9
* Malcolm J. Low, University of Michigan, USA

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 2 of 9
* Roger A. Adan, Brain Center Rudolf Magnus, Netherlands

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 3 of 9
Daniel J. Drucker, Lunenfeld-Tanenbaum Research Institute, Canada
The Control of Gut Hormone Activity: Role of Dipeptidyl Peptidase-4

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall


Coffee Break

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 5 of 9
Matthias H. Tschöp, Helmholtz Zentrum München and Technische Universität München, Germany
Gut Peptide Combination Therapy to Treat Obesity

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 6 of 9
Lora K. Heisler, Rowett Institute, University of Aberdeen, UK
Modifying CNS 5-HT Circuits to Reverse Obesity and Type 2 Diabetes

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 7 of 9
Ruth E. Gimeno, Eli Lilly and Company, USA
Current and Emerging Targets for Obesity Treatment

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 8 of 9
Tamer Coskun, Eli Lilly & Company, USA
Short Talk: Confirming Efficacy of Celastrol and Withaferin A in a Diet-Induced Obese (DIO) Mouse Model

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 9 of 9
Shamina M. Rangwala, Pfizer, USA
Short Talk: Gdf15-Mediated Mechanisms of Food Intake Reduction and Weight Loss

Saturday, May 13 | 11:45AM - 12:30PM
Lunch
Room: Tivoli Congress Hall


Saturday, May 13 | 12:00PM - 2:30PM
Poster Session 4
Room: Vandsalen


Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 1 of 8
* Kate Ellacott, University of Exeter Medical School, UK

Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 2 of 8
* Mads Tang-Christensen, Novo Nordisk A/S, Denmark

Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 3 of 8
Justin J. Rochford, University of Aberdeen, UK
Inhibition of Gamma Synuclein Directly Alters Adipocyte Mitochondrial Function and Lipid Metabolism

Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 4 of 8
Barbara Cannon, Stockholm University, Sweden
Peripheral and Central Regulation of UCP1-Dependent Thermogenesis

Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 5 of 8
Miguel López, Universidad de Santiago de Compostela, Spain
Hypothalamic AMPK: A Canonical Regulator of Energy Balance

Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 6 of 8
Sangho Yu, Pennington Biomedical Research Center, USA
Preoptic Leptin Function Modulates Diet-Induced Weight Gain

Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 7 of 8
Claire H. Feetham, University of Manchester, UK
Prolactin-Releasing Peptide Neurones Project from Dorsomedial to Paraventricular Hypothalamic Nucleus to Affect Energy Expenditure

Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 8 of 8
Pablo B. Martinez de Morentin, Rowett Institute of Nutrition and Health, UK
Raphe Pallidus Serotonin Cells Modulate Brown Adipose Tissue Thermogenesis

Saturday, May 13 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Saturday, May 13 | 5:00PM - 6:45PM
Programming Obesity: Early Environmental Influences
Room: Tivoli Congress Hall

Speaker 1 of 5
* Michael Krashes, NIDDK, National Institutes of Health, USA

Saturday, May 13 | 5:00PM - 6:45PM
Programming Obesity: Early Environmental Influences
Room: Tivoli Congress Hall

Speaker 2 of 5
* Alicja A. Skowronski, Columbia University, USA

Saturday, May 13 | 5:00PM - 6:45PM
Programming Obesity: Early Environmental Influences
Room: Tivoli Congress Hall

Speaker 3 of 5
Elinor L. Sullivan, Oregon National Primate Research Center, USA
Maternal Metabolic and Dietary Environmental Influences on Offspring Metabolic Health and Behavior

Saturday, May 13 | 5:00PM - 6:45PM
Programming Obesity: Early Environmental Influences
Room: Tivoli Congress Hall

Speaker 4 of 5
John Speakman, Institute of Genetics and Developmental Biology, CAS, China
The Impact of Maternal Diet on Hypothalamic Remodeling during Development and Subsequent Susceptibility to High Fat Diets in the Mouse

Saturday, May 13 | 5:00PM - 6:45PM
Programming Obesity: Early Environmental Influences
Room: Tivoli Congress Hall

Speaker 5 of 5
Jens C. Brüning, Max Planck Institute for Metabolism Research, Germany
Effect of Insulin on Brain Development and Metabolic Programming

Saturday, May 13 | 5:00PM - 6:45PM
Novel Aspects of Gut Function
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 1 of 4
* John Furness, University of Melbourne, Australia


Saturday, May 13 | 5:00PM - 6:45PM
Novel Aspects of Gut Function
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 2 of 4
Thue W. Schwartz, University of Copenhagen, Denmark
Nutrient and Gut Microbiota Metabolite Sensing through GPCRs in the GI Tract


Saturday, May 13 | 5:00PM - 6:45PM
Novel Aspects of Gut Function
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 3 of 4
Gilles Mithieux, INSERM, France
Central Regulation of Metabolism Initiated by Intestinal Gluconeogenesis


Saturday, May 13 | 5:00PM - 6:45PM
Novel Aspects of Gut Function
This session is from GI Control of Metabolism
Room: Ballonsalen/Blomstersalen

Speaker 4 of 4
Tony K.T. Lam, Toronto General Research Institute, Canada
Gut Nutrient Sensing


Saturday, May 13 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Tivoli Congress Hall


Saturday, May 13 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
This session is from GI Control of Metabolism
Room: Balloonsalen/Blomstersalen


Saturday, May 13 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Tivoli Congress Hall
No registration fees are used to fund alcohol served at this function.

Saturday, May 13 | 8:00PM - 11:00PM
Entertainment
Room: Tivoli Congress Hall
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources. Novo Nordisk A/S funding is not being used for this function.

Saturday, May 13 | 8:00PM - 11:00PM
Cash Bar
Room: Tivoli Congress Hall


Sunday, May 14 | 10:25AM - 10:25AM
Departure


*Session Chair.