Web Desc
Gastrointestinal Control of Metabolism
joint with Neuronal Control of Appetite, Metabolism and Weight
Organizer(s): Randy J. Seeley, Matthias H. Tschöp and Fiona M. Gribble
Date: May 09 - 13, 2017
Location: Tivoli Hotel and Congress Center, Copenhagen, Denmark
Lead Sponsor: Novo Nordisk A/S. Sponsored by MedImmune
For important information on the coronavirus, please click here
Summary of Meeting:
The twin epidemics of obesity and diabetes pose difficult challenges to the health of growing populations around the globe. A wide array of recent data link the gastrointestinal tract to the etiology of these diseases. Moreover, some of the most innovative approaches to treat obesity, diabetes and related metabolic disorders involve direct manipulation of the GI tract or manipulation of the signals that come from the GI tract. To this end, an important goal of this meeting will be to highlight a wide range of methodologies that can be brought to understand GI function as it relates to obesity and diabetes. One of the primary factors slowing research on this topic is that investigators with interest in GI function and metabolic disease come from a wide range of disciplines that are not generally represented at scientific meetings. A key goal of this meeting is to bring together leading investigators from around the globe. Putting investigators who have been revealing function of the GI tract together with those sophisticated in metabolism – as well as encouraging early-career investigators to delve into this field – will be crucial to accelerate current work looking for novel therapeutic strategies. An important advance in our understanding of the GI tract is the appreciation of it as a major endocrine organ. A key component of the action of those GI hormones is their interaction with both the peripheral and central nervous system. Consequently, this meeting will be held jointly with a meeting that focuses on the “Neuronal Control of Appetite, Metabolism and Weight.” This is an ideal opportunity to bring together those who study how the GI tract generates these signals with those who study the neural systems that are targets for these signals.
Scholarship Deadline: January 12 2017
Discounted Abstract Deadline: January 12 2017
Abstract Deadline: February 9 2017
Discounted Registration Deadline: March 9 2017
Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.


Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
MedImmune
Keystone Symposia thanks our Lead Sponsor for generously supporting this meeting:
Novo Nordisk A/S
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Tuesday, May 09 | 4:00PM - 8:00PM
Arrival and Registration
Room: Foyer


Tuesday, May 09 | 6:00PM - 8:00PM
Welcome Mixer
Room: Brasserie 3
No registration fees are used to fund alcohol served at this function.

Wednesday, May 10 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Wednesday, May 10 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Tivoli Congress Hall

Speaker 1 of 5
* Lora K. Heisler, Rowett Institute, University of Aberdeen, UK

Wednesday, May 10 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Tivoli Congress Hall

Speaker 2 of 5
* Randy J. Seeley, University of Michigan, USA

Wednesday, May 10 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Tivoli Congress Hall

Speaker 3 of 5
Stephen O'Rahilly, University of Cambridge, UK
Metabolic Disease: Lessons from Natural Human Variation

Wednesday, May 10 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Tivoli Congress Hall

Speaker 4 of 5
Klaus H. Kaestner, University of Pennsylvania School of Medicine, USA
The Intestinal Stem Cell Niche – At the Base of It All

Wednesday, May 10 | 8:30AM - 10:00AM
Welcome and Keynote Session (Joint)
Room: Tivoli Congress Hall


Coffee Break

Wednesday, May 10 | 10:20AM - 11:45AM
Nutrient Sensing and Gut Signaling (Joint)
Room: Tivoli Congress Hall

Speaker 1 of 5
* Andrew Butler, St. Louis University, USA

Wednesday, May 10 | 10:20AM - 11:45AM
Nutrient Sensing and Gut Signaling (Joint)
Room: Tivoli Congress Hall

Speaker 2 of 5
* Fiona M. Gribble, University of Cambridge, UK

Wednesday, May 10 | 10:20AM - 11:45AM
Nutrient Sensing and Gut Signaling (Joint)
Room: Tivoli Congress Hall

Speaker 3 of 5
Ronald M. Evans, HHMI/The Salk Institute, USA
Gut Feelings: Systemic Reach of Intestinal FXR

Wednesday, May 10 | 10:20AM - 11:45AM
Nutrient Sensing and Gut Signaling (Joint)
Room: Tivoli Congress Hall

Speaker 4 of 5
Kristina Schoonjans, École Polytechnique Fédérale de Lausanne – EPFL, Switzerland
Bile Acid Signaling in Metabolic Disease

Wednesday, May 10 | 10:20AM - 11:45AM
Nutrient Sensing and Gut Signaling (Joint)
Room: Tivoli Congress Hall

Speaker 5 of 5
Joshua Thaler, University of Washington, USA
Short Talk: Prevention of Microglial Inflammatory Signaling Reduces Susceptibility to Diet-Induced Obesity

Wednesday, May 10 | 11:45AM - 2:30PM
On Own for Lunch


Wednesday, May 10 | 11:45AM - 1:00PM
Poster Setup
Room: Vandsalen


Wednesday, May 10 | 1:00PM - 10:00PM
Poster Viewing
Room: Vandsalen


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
Room: Ballonsalen/Blomstersalen

Speaker 1 of 7
* Timo D. Müller, Institute for Diabetes and Obesity, Germany

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
Room: Ballonsalen/Blomstersalen

Speaker 2 of 7
Anne-Charlotte Jarry, Paris Diderot University, France
Neuromedin U Blocks Gastric Emptying through Vagal-Dependent Mechanisms and Improves Oral Glucose Tolerance

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
Room: Ballonsalen/Blomstersalen

Speaker 3 of 7
Geke Aline Boer, University of Copenhagen, Biomedical Institute, Denmark
Acute Reduction of GIP: Effects on Lipid and Bone Metabolism

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
Room: Ballonsalen/Blomstersalen

Speaker 4 of 7
Emily C. Bruggeman, University of Texas Southwestern Medical Center, USA
Ghrelin Receptor Deletion Increases Morbidity and Mortality in a Prader-Willi Syndrome Mouse Model

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
Room: Ballonsalen/Blomstersalen

Speaker 5 of 7
Natalia Petersen, University of Copenhagen, Denmark
'Tailoring' the Intestinal Epithelium for Type 2 Diabetes Treatment: Modulation of L-Cell Differentiation

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
Room: Ballonsalen/Blomstersalen

Speaker 6 of 7
Hai-Bin Ruan, University of Minnesota, USA
Diet- and Microbiota-Sensitive Intestinal O-GlcNAc Signaling Controls Enteroendocrine Cell Development and Function

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1
Room: Ballonsalen/Blomstersalen

Speaker 7 of 7
Sara Lind Jepsen, University of Copenhagen, Denmark
Somatostatin Regulates GLP-1 Secretion through the Somatostatin Receptor Subtype 2

Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
This session is from Neuronal Control
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 1 of 9
* Thomas Alexander Lutz, University of Zürich, Switzerland


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
This session is from Neuronal Control
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 2 of 9
* Petra Kotzbeck, Medical University of Graz, Austria


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
This session is from Neuronal Control
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 3 of 9
Yong Xu, Baylor College of Medicine, USA
5-HT Neurons and Eating Disorders


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
This session is from Neuronal Control
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 4 of 9
Manon Duquenne, Université Lille 2 - INSERM, France
A Role for Tanycyte Exocytosis in the Central Control of Energy Homeostasis?


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
This session is from Neuronal Control
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 5 of 9
Christian Stockmann, University of Zurich, Switzerland
The Role of Vascular Endothelial Growth Factor-A in the Context of Cancer Cachexia and Chemotherapy


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
This session is from Neuronal Control
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 6 of 9
Kevin G. Murphy, Imperial College London, UK
Investigating Disorders Associated with Weight Loss


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
This session is from Neuronal Control
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 7 of 9
Serge Luquet, Université Paris Diderot, France
Palatability Can Drive Feeding Independent of AgRP Neurons


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
This session is from Neuronal Control
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 8 of 9
Christin Kosse, Francis Crick Institute, UK
Functional Properties of GAD65 Neurons in the Lateral Hypothalamus


Wednesday, May 10 | 2:30PM - 4:30PM
Workshop 1: Disorders and Diseases Associated with Weight Lo
ss
This session is from Neuronal Control
Room: Carstensen
Anorexia nervosa, binge eating disorder, PTSD, cancer cachexia and others
Speaker 9 of 9
Yunlei Yang, SUNY Upstate Medical University, USA
Deciphering Anorexigenic Septohypothalamic Feeding Circuits


Wednesday, May 10 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Wednesday, May 10 | 5:00PM - 7:00PM
Gut Bacteria as Cause and Treatment of Metabolic Diseases
Room: Ballonsalen/Blomstersalen
Gut bacteria as cause and treatment of metabolic diseases.
Speaker 1 of 5
* Gilles Mithieux, INSERM, France

Wednesday, May 10 | 5:00PM - 7:00PM
Gut Bacteria as Cause and Treatment of Metabolic Diseases
Room: Ballonsalen/Blomstersalen
Gut bacteria as cause and treatment of metabolic diseases.
Speaker 2 of 5
Fredrik Bäckhed, University of Gothenburg, Sweden
Microbial Signaling from the Gut and Resulting Effects on Host Metabolism

Wednesday, May 10 | 5:00PM - 7:00PM
Gut Bacteria as Cause and Treatment of Metabolic Diseases
Room: Ballonsalen/Blomstersalen
Gut bacteria as cause and treatment of metabolic diseases.
Speaker 3 of 5
Martin J. Blaser, New York University School of Medicine, USA
Effects of the Early Life Microbiota on the Development of Metabolic Illnesses

Wednesday, May 10 | 5:00PM - 7:00PM
Gut Bacteria as Cause and Treatment of Metabolic Diseases
Room: Ballonsalen/Blomstersalen
Gut bacteria as cause and treatment of metabolic diseases.
Speaker 4 of 5
Karine Clément, INSERM / Sorbonne Universite, France
Microbiome as Therapy

Wednesday, May 10 | 5:00PM - 7:00PM
Gut Bacteria as Cause and Treatment of Metabolic Diseases
Room: Ballonsalen/Blomstersalen
Gut bacteria as cause and treatment of metabolic diseases.
Speaker 5 of 5
Edna A. Trujillo, University of Wisconsin-Madison, USA
Short Talk: Metabolite Profiling of Plasma and Cecum Elucidates the Impacts of Host Genetics and Environment on the Gut Microbiota

Wednesday, May 10 | 5:00PM - 7:00PM
Interactions between Ingestive Signals and Reward Circuits
This session is from Neuronal Control
Room: Carstensen

Speaker 1 of 6
* Matt Carter, Williams College, USA


Wednesday, May 10 | 5:00PM - 7:00PM
Interactions between Ingestive Signals and Reward Circuits
This session is from Neuronal Control
Room: Carstensen

Speaker 2 of 6
* Agatha A. van der Klaauw, University of Cambridge, UK


Wednesday, May 10 | 5:00PM - 7:00PM
Interactions between Ingestive Signals and Reward Circuits
This session is from Neuronal Control
Room: Carstensen

Speaker 3 of 6
Michael A. Cowley, Monash University, Australia
Leptin Receptor Expressing Neurons of the Dorsomedial Hypothalamus Play a Limited Role in Regulating Food Intake but a Critical Role in Regulating Metabolism


Wednesday, May 10 | 5:00PM - 7:00PM
Interactions between Ingestive Signals and Reward Circuits
This session is from Neuronal Control
Room: Carstensen

Speaker 4 of 6
Suzanne Lee Dickson, Sahlgrenska Academy, Gothenburg University, Sweden
Brain Ghrelin Signaling and Food Reward Behavior


Wednesday, May 10 | 5:00PM - 7:00PM
Interactions between Ingestive Signals and Reward Circuits
This session is from Neuronal Control
Room: Carstensen

Speaker 5 of 6
Christian Lüscher, University of Geneva, Switzerland
Feeding Circuits that Can Override Metabolic Needs


Wednesday, May 10 | 5:00PM - 7:00PM
Interactions between Ingestive Signals and Reward Circuits
This session is from Neuronal Control
Room: Carstensen

Speaker 6 of 6
Claire J. Foldi, Monash University, Australia
Short Talk: CNS Reward Pathways in Anorexia Nervosa: Insights from a Rat Model


Wednesday, May 10 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Vandsalen
No registration fees are used to fund alcohol served at this function.

Wednesday, May 10 | 7:30PM - 10:00PM
Poster Session 1
Room: Vandsalen


Thursday, May 11 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut–Pancreas Development I
Room: Ballonsalen/Blomstersalen

Speaker 1 of 8
* Praveen Sethupathy, Cornell University, USA

Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut–Pancreas Development I
Room: Ballonsalen/Blomstersalen

Speaker 2 of 8
Fiona M. Gribble, University of Cambridge, UK
The Biology of Enteroendocrine Cells

Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut–Pancreas Development I
Room: Ballonsalen/Blomstersalen

Speaker 3 of 8
Heiko Lickert, Institute of Diabetes and Regeneration, Germany
Dissecting Intestinal Stem Cell Lineage Decisions

Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut–Pancreas Development I
Room: Ballonsalen/Blomstersalen


Coffee Break

Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut–Pancreas Development I
Room: Ballonsalen/Blomstersalen

Speaker 5 of 8
James M. Wells, Cincinnati Children's Hospital Research Foundation, USA
Human Pluripotent Stem Cell-Derived Gastrointestinal Organoids as New Models to Study Metabolic and Digestive Diseases

Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut–Pancreas Development I
Room: Ballonsalen/Blomstersalen

Speaker 6 of 8
Lori Sussel, University of Colorado Anschutz Medical Campus, USA
Loss of Beta Cell Identity Related to Diabetes

Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut–Pancreas Development I
Room: Ballonsalen/Blomstersalen

Speaker 7 of 8
John Furness, University of Melbourne, Australia
Short Talk: Diversity of Enteroendocrine Cells between Species and Regions Studied at a Cellular and Subcellular Level

Thursday, May 11 | 8:30AM - 11:45AM
Stem Cells, Gut–Pancreas Development I
Room: Ballonsalen/Blomstersalen

Speaker 8 of 8
Sandra Guilmeau, Institut Cochin, INSERM U1016, CNRS UMR 8104, France
Short Talk: Contribution of ChREBP in Intestinal GLP-1 Production

Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 1 of 9
* Qingchun Tong, University of Texas Medical School, USA


Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 2 of 9
* Matthew R. Hayes, University of Pennsylvania, USA


Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 3 of 9
Sabrina Diano, Yale University School of Medicine, USA
Mitochondrial Control of the Melanocortin System


Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 4 of 9
Martin G. Myers, Jr., University of Michigan, USA
LepRb Signaling and the Regulation of Transcription


Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
This session is from Neuronal Control
Room: Tivoli Congress Hall


Coffee Break


Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 6 of 9
Joseph T. Bass, Northwestern University, USA
Identification of an SCN-AgRP Circadian Neurocircuit Regulating Obesity and Systemic Metabolism


Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 7 of 9
Lori M. Zeltser, Columbia University, USA
Gene X Environment Interactions that Promote Anorexia-Like Behavior


Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 8 of 9
Ali Guler, University of Virginia, USA
Short Talk: Dopamine Signaling in the SCN Regulates Circadian Consumption of High-Fat Diet


Thursday, May 11 | 8:30AM - 11:45AM
Emerging Energy Homeostasis Neurocircuitry
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 9 of 9
Mathias Treier, Max-Delbrueck-Center for Molecular Medicine, Germany
Short Talk: Identification of the Hypothalamic Circuit Maintaining Food Foraging


Thursday, May 11 | 11:45AM - 5:00PM
On Own for Lunch


Thursday, May 11 | 11:45AM - 1:00PM
Poster Setup
Room: Vandsalen


Thursday, May 11 | 1:00PM - 10:00PM
Poster Viewing
Room: Vandsalen


Thursday, May 11 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Thursday, May 11 | 5:00PM - 7:00PM
Signaling from Periphery to Brain to Modulate Energy Balance
(Joint)

Room: Tivoli Congress Hall

Speaker 1 of 6
* Suzanne M. Appleyard, Washington State University, USA

Thursday, May 11 | 5:00PM - 7:00PM
Signaling from Periphery to Brain to Modulate Energy Balance
(Joint)

Room: Tivoli Congress Hall

Speaker 2 of 6
* David Olson, University of Michigan, USA

Thursday, May 11 | 5:00PM - 7:00PM
Signaling from Periphery to Brain to Modulate Energy Balance
(Joint)

Room: Tivoli Congress Hall

Speaker 3 of 6
Jeffrey M. Friedman, Rockefeller University, USA
Neural Control of Food Intake, Locomotion and Glucose Metabolism

Thursday, May 11 | 5:00PM - 7:00PM
Signaling from Periphery to Brain to Modulate Energy Balance
(Joint)

Room: Tivoli Congress Hall

Speaker 4 of 6
Randy J. Seeley, University of Michigan, USA
How the Gut Regulates Metabolic Status

Thursday, May 11 | 5:00PM - 7:00PM
Signaling from Periphery to Brain to Modulate Energy Balance
(Joint)

Room: Tivoli Congress Hall

Speaker 5 of 6
Ivan E. de Araujo, Icahn School of Medicine at Mount Sinai, USA
What Does Sugar Do to the Brain? Circuit Logic for Sugar Sensing

Thursday, May 11 | 5:00PM - 7:00PM
Signaling from Periphery to Brain to Modulate Energy Balance
(Joint)

Room: Tivoli Congress Hall

Speaker 6 of 6
Celine E. Riera, Cedars-Sinai Medical Center, USA
Short Talk: The Sense of Smell Impacts Metabolic Health and Obesity

Thursday, May 11 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Tivoli Congress Hall
No registration fees are used to fund alcohol served at this function.

Thursday, May 11 | 7:30PM - 10:00PM
Poster Session 2
Room: Vandsalen


Friday, May 12 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines – What Does the Future Hold?

Room: Ballonsalen/Blomstersalen

Speaker 1 of 8
* Ruth E. Gimeno, Eli Lilly and Company, USA

Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines – What Does the Future Hold?

Room: Ballonsalen/Blomstersalen

Speaker 2 of 8
Jens Juul Holst, University of Copenhagen the Panum Institute, Denmark
The Role of the Gut in the Development of Type 2 Diabetes

Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines – What Does the Future Hold?

Room: Ballonsalen/Blomstersalen

Speaker 3 of 8
Tricia M. Tan, Imperial College London, UK
Triple Gut Hormones as Therapy

Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines – What Does the Future Hold?

Room: Ballonsalen/Blomstersalen


Coffee Break

Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines – What Does the Future Hold?

Room: Ballonsalen/Blomstersalen

Speaker 5 of 8
David E. Cummings, University of Washington, USA
Metabolic Surgery: Mechanisms and Use of “Bariatric” Operations to Treat Type 2 Diabetes


Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines – What Does the Future Hold?

Room: Ballonsalen/Blomstersalen

Speaker 6 of 8
Niels Vrang, Gubra, Denmark
Short Talk: The Effect of FXR, PPAR-a/d and GLP-1 Agonism on Liver Disease in Diet-Induced Obese and Biopsy-Confirmed Mouse Models of NASH

Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines – What Does the Future Hold?

Room: Ballonsalen/Blomstersalen

Speaker 7 of 8
Wendy M. McKimpson, Columbia University, USA
Short Talk: Foxo1-Expressing Cells in the Gut as a Source of Insulin for Diabetes Treatment

Friday, May 12 | 8:30AM - 11:30AM
Controversies in Obesity/Diabetes Treatment: Surgery vs. Dev
ices vs. Medicines – What Does the Future Hold?

Room: Ballonsalen/Blomstersalen

Speaker 8 of 8
Makoto Fukuda, Baylor College of Medicine, USA
Short Talk: Gut Hormone GIP Drives Hypothalamic Pathogenesis of Obesity

Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 1 of 9
* Clemence Blouet, University of Cambridge, UK


Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 2 of 9
* J. Nicholas Betley, University of Pennsylvania, USA


Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 3 of 9
Scott M. Sternson, HHMI/Janelia Research Campus, USA
Motivational Mechanisms Controlling Hunger


Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 4 of 9
Garret D. Stuber, University of North Carolina at Chapel Hill School of Medicine, USA
Lateral Hypothalamic Circuits for Feeding and Reward


Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
This session is from Neuronal Control
Room: Tivoli Congress Hall


Coffee Break


Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 6 of 9
Tamas L. Horvath, Yale School of Medicine, USA
Appetite Circuits in the Regulation of Complex Behavior


Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 7 of 9
Roger D. Cone, University of Michigan, USA
Melanocortins: From Pharmacology to Pharmacotherapy


Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 8 of 9
Tatiana Korotkova, Max Planck Institute for Metabolism Research, Germany
Short Talk: Gamma Oscillations Organize Top-Down Signaling to Hypothalamus and Enable Food-Seeking


Friday, May 12 | 8:30AM - 11:45AM
Hypothalamic Signals Modulating Hunger and Complex Behavior
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 9 of 9
Marcelo O. Dietrich, Yale University, USA
Short Talk: Behavioral Ontogeny of Hypothalamic Neurons


Friday, May 12 | 11:30AM - 2:30PM
On Own for Lunch


Friday, May 12 | 11:30AM - 1:00PM
Poster Setup
Room: Vandsalen


Friday, May 12 | 1:00PM - 10:00PM
Poster Viewing
Room: Vandsalen


Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
Room: Ballonsalen/Blomstersalen

Speaker 1 of 8
* Lene Jessen, Zealand Pharma, Denmark

Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
Room: Ballonsalen/Blomstersalen

Speaker 2 of 8
Maria H. Hauge, Copenhagen University, Denmark
Gq and Gs Signaling Acting in Synergy to Control GLP-1 Secretion

Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
Room: Ballonsalen/Blomstersalen

Speaker 3 of 8
Youngjung R. Kim, Columbia University, USA
Pyruvate Kinase as a Novel Metabolic Regulator of Beta Cell Loss in Diabetes

Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
Room: Ballonsalen/Blomstersalen

Speaker 4 of 8
Alyce M. Martin, Flinders University, Australia
Gut Serotonin Is a Signaling Nexus between the Gut Microbiome and Host Metabolism

Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
Room: Ballonsalen/Blomstersalen

Speaker 5 of 8
Louise Olofsson, University of Gothenburg, Sweden
Role of the Gut Microbiota in Diet-Induced Hypothalamic Inflammation

Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
Room: Ballonsalen/Blomstersalen

Speaker 6 of 8
Anette Christ, University of Massachusetts Medical School, USA
Long-Term Epigenetic Re-Programming of Myeloid Precursor Cells in a Hyperlipidemic Environment

Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
Room: Ballonsalen/Blomstersalen

Speaker 7 of 8
Nadja Gebert, Leibniz Institute on Aging, Germany
Age and Diet Affect the Intestinal Crypt Proteome

Friday, May 12 | 2:30PM - 4:30PM
Workshop 2
Room: Ballonsalen/Blomstersalen

Speaker 8 of 8
Jonathan D. Douros, Duke University, USA
Increased Glucose-Dependent Insulinotropic Polypeptide (GIP) Secretion and Signaling Improves Beta-Cell Function following Vertical Sleeve Gastrectomy (VSG)

Friday, May 12 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Friday, May 12 | 5:00PM - 7:00PM
Stem Cells, Gut-Pancreas Development II
Room: Ballonsalen/Blomstersalen

Speaker 1 of 5
* Lori Sussel, University of Colorado Anschutz Medical Campus, USA

Friday, May 12 | 5:00PM - 7:00PM
Stem Cells, Gut-Pancreas Development II
Room: Ballonsalen/Blomstersalen

Speaker 2 of 5
Andrew B. Leiter, University of Massachusetts Medical School, USA
Differentiation of Enteroendocrine Cells

Friday, May 12 | 5:00PM - 7:00PM
Stem Cells, Gut-Pancreas Development II
Room: Ballonsalen/Blomstersalen

Speaker 3 of 5
Praveen Sethupathy, Cornell University, USA
Microbiota, MicroRNAs, and Intestinal Stem Cell Function

Friday, May 12 | 5:00PM - 7:00PM
Stem Cells, Gut-Pancreas Development II
Room: Ballonsalen/Blomstersalen

Speaker 4 of 5
Susumu Seino, Kobe University Graduate School of Medicine, Japan
Beta-Cell Glutamate Signaling Is Critical for Incretin-Induced Insulin Secretion

Friday, May 12 | 5:00PM - 7:00PM
Stem Cells, Gut-Pancreas Development II
Room: Ballonsalen/Blomstersalen

Speaker 5 of 5
William L. Holland, University of Texas Southwestern Medical Center, USA
Short Talk: Glucagon Receptor Inhibition Restores Functional Beta Cell Mass and Reverses Hyperglycemia in Type-1 Diabetic Mice

Friday, May 12 | 5:00PM - 7:00PM
Cutting-Edge Approaches in Obesity Research
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 1 of 6
* Jeffrey M. Zigman, University of Texas Southwestern Medical Center, USA


Friday, May 12 | 5:00PM - 7:00PM
Cutting-Edge Approaches in Obesity Research
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 2 of 6
* Daniela Cota, Neurocentre Magendie, France


Friday, May 12 | 5:00PM - 7:00PM
Cutting-Edge Approaches in Obesity Research
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 3 of 6
Stephen Liberles, Harvard Medical School, USA
Molecular and Genetic Analysis of the Vagus Nerve


Friday, May 12 | 5:00PM - 7:00PM
Cutting-Edge Approaches in Obesity Research
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 4 of 6
Andres Lozano, University of Toronto, Toronto Western Hospital, Canada
Deep Brain Stimulation to Treat Obesity or Anorexia


Friday, May 12 | 5:00PM - 7:00PM
Cutting-Edge Approaches in Obesity Research
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 5 of 6
Kevin L. Grove, Novo Nordisk, USA
Obesity-Related Genes in the Rhesus Macaque


Friday, May 12 | 5:00PM - 7:00PM
Cutting-Edge Approaches in Obesity Research
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 6 of 6
John N. Campbell, University of Virginia, USA
Short Talk: A Molecular Census of Arcuate Hypothalamus and Median Eminence Cell Types


Friday, May 12 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Tivoli Congress Hall
No registration fees are used to fund alcohol served at this function.

Friday, May 12 | 7:30PM - 10:00PM
Poster Session 3
Room: Vandsalen


Saturday, May 13 | 7:30AM - 8:30AM
Breakfast
Room: Individual Hotel


Saturday, May 13 | 8:00AM - 8:30AM
Poster Setup
Room: Vandsalen


Saturday, May 13 | 8:30AM - 5:00PM
Poster Viewing
Room: Vandsalen


Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 1 of 9
* Malcolm J. Low, University of Michigan, USA

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 2 of 9
* Roger A. Adan, Brain Center Rudolf Magnus, Netherlands

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 3 of 9
Daniel J. Drucker, Lunenfeld-Tanenbaum Research Institute, Canada
The Control of Gut Hormone Activity: Role of Dipeptidyl Peptidase-4

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 4 of 9
Matthias H. Tschöp, Helmholtz Zentrum München and Technische Universität München, Germany
Gut Peptide Combination Therapy to Treat Obesity

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall


Coffee Break

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 6 of 9
Lora K. Heisler, Rowett Institute, University of Aberdeen, UK
Modifying CNS 5-HT Circuits to Reverse Obesity and Type 2 Diabetes

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 7 of 9
Ruth E. Gimeno, Eli Lilly and Company, USA
Current and Emerging Targets for Obesity Treatment

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 8 of 9
Tamer Coskun, Eli Lilly & Company, USA
Short Talk: Confirming Efficacy of Celastrol and Withaferin A in a Diet-Induced Obese (DIO) Mouse Model

Saturday, May 13 | 8:30AM - 11:45AM
Pharmacotherapies for Obesity and Type 2 Diabetes (Joint)
Room: Tivoli Congress Hall

Speaker 9 of 9
Shamina M. Rangwala, Pfizer, USA
Short Talk: Gdf15-Mediated Mechanisms of Food Intake Reduction and Weight Loss

Saturday, May 13 | 11:45AM - 12:30PM
Lunch
Room: Tivoli Congress Hall


Saturday, May 13 | 12:00PM - 2:30PM
Poster Session 4
Room: Vandsalen


Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
This session is from Neuronal Control
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 1 of 8
* Kate Ellacott, University of Exeter Medical School, UK


Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
This session is from Neuronal Control
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 2 of 8
* Mads Tang-Christensen, Novo Nordisk A/S, Denmark


Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
This session is from Neuronal Control
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 3 of 8
Justin J. Rochford, University of Aberdeen, UK
Inhibition of Gamma Synuclein Directly Alters Adipocyte Mitochondrial Function and Lipid Metabolism


Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
This session is from Neuronal Control
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 4 of 8
Barbara Cannon, Stockholm University, Sweden
Peripheral and Central Regulation of UCP1-Dependent Thermogenesis


Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
This session is from Neuronal Control
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 5 of 8
Miguel López, Universidad de Santiago de Compostela, Spain
Hypothalamic AMPK: A Canonical Regulator of Energy Balance


Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
This session is from Neuronal Control
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 6 of 8
Sangho Yu, Pennington Biomedical Research Center, USA
Preoptic Leptin Function Modulates Diet-Induced Weight Gain


Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
This session is from Neuronal Control
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 7 of 8
Claire H. Feetham, University of Manchester, UK
Prolactin-Releasing Peptide Neurones Project from Dorsomedial to Paraventricular Hypothalamic Nucleus to Affect Energy Expenditure


Saturday, May 13 | 2:30PM - 4:30PM
Workshop 2: CNS Regulation of Adipose Tissue
This session is from Neuronal Control
Room: Tivoli Congress Hall
CNS regulation of white and brown fat and browning of white fat
Speaker 8 of 8
Pablo B. Martinez de Morentin, Rowett Institute of Nutrition and Health, UK
Raphe Pallidus Serotonin Cells Modulate Brown Adipose Tissue Thermogenesis


Saturday, May 13 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Saturday, May 13 | 5:00PM - 6:45PM
Novel Aspects of Gut Function
Room: Ballonsalen/Blomstersalen

Speaker 1 of 4
* John Furness, University of Melbourne, Australia

Saturday, May 13 | 5:00PM - 6:45PM
Novel Aspects of Gut Function
Room: Ballonsalen/Blomstersalen

Speaker 2 of 4
Thue W. Schwartz, University of Copenhagen, Denmark
Nutrient and Gut Microbiota Metabolite Sensing through GPCRs in the GI Tract

Saturday, May 13 | 5:00PM - 6:45PM
Novel Aspects of Gut Function
Room: Ballonsalen/Blomstersalen

Speaker 3 of 4
Gilles Mithieux, INSERM, France
Central Regulation of Metabolism Initiated by Intestinal Gluconeogenesis

Saturday, May 13 | 5:00PM - 6:45PM
Novel Aspects of Gut Function
Room: Ballonsalen/Blomstersalen

Speaker 4 of 4
Tony K.T. Lam, Toronto General Research Institute, Canada
Gut Nutrient Sensing

Saturday, May 13 | 5:00PM - 6:45PM
Programming Obesity: Early Environmental Influences
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 1 of 5
* Michael Krashes, NIDDK, National Institutes of Health, USA


Saturday, May 13 | 5:00PM - 6:45PM
Programming Obesity: Early Environmental Influences
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 2 of 5
* Alicja A. Skowronski, Columbia University, USA


Saturday, May 13 | 5:00PM - 6:45PM
Programming Obesity: Early Environmental Influences
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 3 of 5
Elinor L. Sullivan, Oregon National Primate Research Center, USA
Maternal Metabolic and Dietary Environmental Influences on Offspring Metabolic Health and Behavior


Saturday, May 13 | 5:00PM - 6:45PM
Programming Obesity: Early Environmental Influences
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 4 of 5
John Speakman, Institute of Genetics and Developmental Biology, CAS, China
The Impact of Maternal Diet on Hypothalamic Remodeling during Development and Subsequent Susceptibility to High Fat Diets in the Mouse


Saturday, May 13 | 5:00PM - 6:45PM
Programming Obesity: Early Environmental Influences
This session is from Neuronal Control
Room: Tivoli Congress Hall

Speaker 5 of 5
Jens C. Brüning, Max Planck Institute for Metabolism Research, Germany
Effect of Insulin on Brain Development and Metabolic Programming


Saturday, May 13 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Balloonsalen/Blomstersalen


Saturday, May 13 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
This session is from Neuronal Control
Room: Tivoli Congress Hall


Saturday, May 13 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Tivoli Congress Hall
No registration fees are used to fund alcohol served at this function.

Saturday, May 13 | 8:00PM - 11:00PM
Entertainment
Room: Tivoli Congress Hall
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources. Novo Nordisk A/S funding is not being used for this function.

Saturday, May 13 | 8:00PM - 11:00PM
Cash Bar
Room: Tivoli Congress Hall


Sunday, May 14 | 10:24AM - 10:24AM
Departure


*Session Chair
†Invited, not yet responded.