Web Desc
Heart Failure: Crossing the Translational Divide
Organizer(s): Yibin Wang, Joseph A. Hill and Carolyn Lam
Date: January 14 - 18, 2018
Location: Keystone Resort, Keystone, CO, USA
Sponsored by Amgen Inc.
Summary of Meeting:
Heart failure is a major human disease that afflicts millions of people worldwide. Intensive research in the past decade has yielded many exciting new mechanistic insights into the pathogenesis of heart failure, but progress toward successful therapies to prevent, halt and reverse heart failure has been painfully slow. The overall goal of this Keystone Symposia conference is to focus on heart failure and highlight the scientific advances in basic discovery and early-phase therapeutic development in this fast-moving field. The symposium will provide the field with an opportunity for robust discussion about the major issues crossing the translational divide from basic discovery to therapies.
Scholarship Deadline: September 21 2017
Discounted Abstract Deadline: September 21 2017
Abstract Deadline: October 19 2017
Discounted Registration Deadline: November 20 2017
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

Amgen Inc.
We gratefully acknowledge additional support for this conference from:
Cytokinetics, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Heart, Lung, and Blood Institute (NHLBI)
Grant No. 1 R13 HL140913-01
Funding for this conference was made possible (in part) by 1 R13 HL140913-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, January 14 | 4:00PM - 8:00PM
Arrival and Registration
Room: Shavano Peak Foyer


Sunday, January 14 | 6:00PM - 8:00PM
Welcome Mixer
Room: Shavano Peak Foyer
No registration fees are used to fund alcohol served at this function.

Monday, January 15 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Monday, January 15 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Crestone/Red Cloud

Speaker 1 of 3
* Yibin Wang, University of California, Los Angeles, David Geffen School of Medicine, USA

Monday, January 15 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Crestone/Red Cloud

Speaker 2 of 3
* Joseph A. Hill, University of Texas Southwestern Medical Center, USA

Monday, January 15 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Crestone/Red Cloud

Speaker 3 of 3
David C. Page, Whitehead Institute for Biomedical Research, USA
Sex and Disease: Do Males and Females Read their Genomes Differently?

Monday, January 15 | 9:00AM - 11:30AM
HFrEF: Ischemic Heart Disease (I/R Injury and Cell Death)
Room: Crestone/Red Cloud

Speaker 1 of 8
* Issei Komuro, Tokyo University Graduate School, Japan

Monday, January 15 | 9:00AM - 11:30AM
HFrEF: Ischemic Heart Disease (I/R Injury and Cell Death)
Room: Crestone/Red Cloud

Speaker 2 of 8
* Zhao Wang, University of Texas Southwestern Medical Center, USA

Monday, January 15 | 9:00AM - 11:30AM
HFrEF: Ischemic Heart Disease (I/R Injury and Cell Death)
Room: Crestone/Red Cloud

Speaker 3 of 8
Laura Mauri, Brigham and Women's Hospital, USA
What Ischemic HFrEF Looks like Clinically and What I Wish I Had in My Toolbox

Monday, January 15 | 9:00AM - 11:30AM
HFrEF: Ischemic Heart Disease (I/R Injury and Cell Death)
Room: Crestone/Red Cloud


Coffee Break

Monday, January 15 | 9:00AM - 11:30AM
HFrEF: Ischemic Heart Disease (I/R Injury and Cell Death)
Room: Crestone/Red Cloud

Speaker 5 of 8
Richard N. Kitsis, Albert Einstein College of Medicine, USA
Understanding and Therapeutically Manipulating Cell Death in the Heart

Monday, January 15 | 9:00AM - 11:30AM
HFrEF: Ischemic Heart Disease (I/R Injury and Cell Death)
Room: Crestone/Red Cloud

Speaker 6 of 8
Junichi Sadoshima, Rutgers New Jersey Medical School, USA
Autosis Mediates Myocardial Cell Death During Ischemia/Reperfusion

Monday, January 15 | 9:00AM - 11:30AM
HFrEF: Ischemic Heart Disease (I/R Injury and Cell Death)
Room: Crestone/Red Cloud

Speaker 7 of 8
Yusuke Morita, Kyoto University, Japan
Short Talk: Spatiotemporal and Integrative Analysis of the Transcriptome and Metabolome Response to Systemic Energetic Starvation with Cardiac Dysfunction

Monday, January 15 | 9:00AM - 11:30AM
HFrEF: Ischemic Heart Disease (I/R Injury and Cell Death)
Room: Crestone/Red Cloud

Speaker 8 of 8
Dipayan Chaudhuri, University of Utah, USA
Short Talk: Mitochondrial Cardiomyopathies Feature Compensatory Increases in Mitochondrial Calcium

Monday, January 15 | 11:30AM - 5:00PM
On Own for Lunch


Monday, January 15 | 11:30AM - 1:00PM
Poster Setup
Room: Shavano/Torreys


Monday, January 15 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys


Monday, January 15 | 2:30PM - 4:30PM
Workshop and Panel 1: Does an X or Y Make a Difference for t
he Heart?
Room: Crestone/Red Cloud

Speaker 1 of 5
* Joseph A. Hill, University of Texas Southwestern Medical Center, USA
Does XX or XY Make the Heart Grow Fonder?

Monday, January 15 | 2:30PM - 4:30PM
Workshop and Panel 1: Does an X or Y Make a Difference for t
he Heart?
Room: Crestone/Red Cloud

Speaker 2 of 5
Leslie A. Leinwand, University of Colorado Boulder, USA
A Woman is Not a Small Man: Sex Differences in the Heart

Monday, January 15 | 2:30PM - 4:30PM
Workshop and Panel 1: Does an X or Y Make a Difference for t
he Heart?
Room: Crestone/Red Cloud

Speaker 3 of 5
David C. Page, Whitehead Institute for Biomedical Research, USA
Translate Mechanism to Practice: For Sex Differences in HF

Monday, January 15 | 2:30PM - 4:30PM
Workshop and Panel 1: Does an X or Y Make a Difference for t
he Heart?
Room: Crestone/Red Cloud

Speaker 4 of 5
* Vera Regitz-Zagrosek, Charité - University Medicine Berlin, Germany
Translational Aspects of Sex Differences in Myocardial Ischemia and Hypertrophy

Monday, January 15 | 2:30PM - 4:30PM
Workshop and Panel 1: Does an X or Y Make a Difference for t
he Heart?
Room: Crestone/Red Cloud

Speaker 5 of 5
Carolyn Lam, Duke-NUS Medical School, Singapore
Sex Differences in HF-Clinical Trial

Monday, January 15 | 4:30PM - 5:00PM
Coffee Available
Room: Shavano Peak Foyer


Monday, January 15 | 5:00PM - 7:00PM
Inflammation (Non-Ischemic) HFrEF
Room: Crestone/Red Cloud

Speaker 1 of 7
* Donald R. Menick, Medical University of South Carolina, USA

Monday, January 15 | 5:00PM - 7:00PM
Inflammation (Non-Ischemic) HFrEF
Room: Crestone/Red Cloud

Speaker 2 of 7
* Merry L. Lindsey, University of Nebraska Medical Center., USA

Monday, January 15 | 5:00PM - 7:00PM
Inflammation (Non-Ischemic) HFrEF
Room: Crestone/Red Cloud

Speaker 3 of 7
Douglas L. Mann, Washington University School of Medicine, USA
What Inflammatory Cardiomyopathy Looks like Clinically and What I Wish I Had in My Toolbox

Monday, January 15 | 5:00PM - 7:00PM
Inflammation (Non-Ischemic) HFrEF
Room: Crestone/Red Cloud

Speaker 4 of 7
Peter Liu, University of Ottawa Heart Institute, Canada
Immune System as Sensor/Mediator for Progression in Heart Failure – Translational Considerations

Monday, January 15 | 5:00PM - 7:00PM
Inflammation (Non-Ischemic) HFrEF
Room: Crestone/Red Cloud

Speaker 5 of 7
Georg Daniel Duerr, University of Bonn, Germany
Short Talk: Post-Conditioning with CpG-Containing TLR9 Ligand 1668-thioate Attenuates Inflammatory Response and Remodeling Leading to Less Fibrosis and Better Left Ventricular Function in Murine Myocardial Infarction

Monday, January 15 | 5:00PM - 7:00PM
Inflammation (Non-Ischemic) HFrEF
Room: Crestone/Red Cloud

Speaker 6 of 7
Dian Cao, University of Texas Southwestern Medical Center, USA
Short Talk: Cytosolic DNA Sensing Governs Myocardial Ischemic Injury by Promoting Macrophage Transformation

Monday, January 15 | 5:00PM - 7:00PM
Inflammation (Non-Ischemic) HFrEF
Room: Crestone/Red Cloud

Speaker 7 of 7
Shey-Shing Sheu, Thomas Jefferson University, USA
Short Talk: Mitochondrial Fission Protein Drp1 Clustered at the Sarcoplasmic Reticulum-Mitochondria Junctions to Regulate Cardiac Excitation-Contraction-Energetics Coupling

Monday, January 15 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Shavano/Torreys
No registration fees are used to fund alcohol served at this function.

Monday, January 15 | 7:30PM - 10:00PM
Poster Session 1
Room: Shavano/Torreys


Tuesday, January 16 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Tuesday, January 16 | 8:00AM - 11:15AM
HFrEF: Hypertensive Heart Disease (Hypertrophy, Fibrosis)
Room: Crestone/Red Cloud

Speaker 1 of 9
* Hina Chaudhry, Mount Sinai School of Medicine, USA

Tuesday, January 16 | 8:00AM - 11:15AM
HFrEF: Hypertensive Heart Disease (Hypertrophy, Fibrosis)
Room: Crestone/Red Cloud

Speaker 2 of 9
* Dan Tong, University of Texas Southwestern Medical Center, USA

Tuesday, January 16 | 8:00AM - 11:15AM
HFrEF: Hypertensive Heart Disease (Hypertrophy, Fibrosis)
Room: Crestone/Red Cloud

Speaker 3 of 9
Joseph A. Hill, University of Texas Southwestern Medical Center, USA
What Hypertensive HFrEF Looks Like and What I Wish I Had in my Toolbox

Tuesday, January 16 | 8:00AM - 11:15AM
HFrEF: Hypertensive Heart Disease (Hypertrophy, Fibrosis)
Room: Crestone/Red Cloud

Speaker 4 of 9
Jeffery D. Molkentin, Cincinnati Children's Hospital Medical Center, USA
Fibroblast Dynamics in the MI-Injured Heart

Tuesday, January 16 | 8:00AM - 11:15AM
HFrEF: Hypertensive Heart Disease (Hypertrophy, Fibrosis)
Room: Crestone/Red Cloud


Coffee Break

Tuesday, January 16 | 8:00AM - 11:15AM
HFrEF: Hypertensive Heart Disease (Hypertrophy, Fibrosis)
Room: Crestone/Red Cloud

Speaker 6 of 9
Mark E. Anderson, Johns Hopkins University School of Medicine, USA
CaMKII as a Therapeutic Target in Heart Failure and Arrhythmias


Tuesday, January 16 | 8:00AM - 11:15AM
HFrEF: Hypertensive Heart Disease (Hypertrophy, Fibrosis)
Room: Crestone/Red Cloud

Speaker 7 of 9
Timothy A. McKinsey, University of Colorado Denver, USA
Epigenetic Regulation of Heart Failure

Tuesday, January 16 | 8:00AM - 11:15AM
HFrEF: Hypertensive Heart Disease (Hypertrophy, Fibrosis)
Room: Crestone/Red Cloud

Speaker 8 of 9
Toshiyuki Ko, University of Tokyo, Japan
Short Talk: Single-Cell Analysis of Non-Cardiomyocytes Reveals a Critical Regulator of Cardiac Homeostasis

Tuesday, January 16 | 8:00AM - 11:15AM
HFrEF: Hypertensive Heart Disease (Hypertrophy, Fibrosis)
Room: Crestone/Red Cloud

Speaker 9 of 9
Rajan Jain, University of Pennsylvania, School of Medicine, USA
Short Talk: The Role of Nuclear Architecture in Myocyte Determination and Genetic Cardiomyopathy

Tuesday, January 16 | 11:15AM - 5:00PM
On Own for Lunch


Tuesday, January 16 | 11:15AM - 1:00PM
Poster Setup
Room: Shavano/Torreys


Tuesday, January 16 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys


Tuesday, January 16 | 2:30PM - 4:30PM
Workshop and Panel 2: Big Data and Precision Medicine for He
art Failure
Room: Crestone/Red Cloud
-Precision medicine: What does it mean?
-Conceptual foundation of precision medicine
-Precision medicine in HF clinical practice
-Precision medicine in drug discovery and clinical trials
Speaker 1 of 4
* Thomas Vondriska, University of California, Los Angeles, USA

Tuesday, January 16 | 2:30PM - 4:30PM
Workshop and Panel 2: Big Data and Precision Medicine for He
art Failure
Room: Crestone/Red Cloud
-Precision medicine: What does it mean?
-Conceptual foundation of precision medicine
-Precision medicine in HF clinical practice
-Precision medicine in drug discovery and clinical trials
Speaker 2 of 4
Peipei Ping, University of California, Los Angeles, USA
Data Science in CV Biology and Medicine

Tuesday, January 16 | 2:30PM - 4:30PM
Workshop and Panel 2: Big Data and Precision Medicine for He
art Failure
Room: Crestone/Red Cloud
-Precision medicine: What does it mean?
-Conceptual foundation of precision medicine
-Precision medicine in HF clinical practice
-Precision medicine in drug discovery and clinical trials
Speaker 3 of 4
Elizabeth M. McNally, Northwestern University, USA
Genomic Solutions to Precision Medicine

Tuesday, January 16 | 2:30PM - 4:30PM
Workshop and Panel 2: Big Data and Precision Medicine for He
art Failure
Room: Crestone/Red Cloud
-Precision medicine: What does it mean?
-Conceptual foundation of precision medicine
-Precision medicine in HF clinical practice
-Precision medicine in drug discovery and clinical trials
Speaker 4 of 4
Daniel P. Kelly, University of Pennsylvania, USA
Integrated Profiling Approaches to Delineating the Metabolic Origins of Heart Failure

Tuesday, January 16 | 4:30PM - 5:00PM
Coffee Available
Room: Shavano Peak Foyer


Tuesday, January 16 | 5:00PM - 7:15PM
PH and RV Failure
Room: Crestone/Red Cloud

Speaker 1 of 6
* Kristina Lorenz, Leibniz Institute for Analytical Sciences- ISAS, Germany

Tuesday, January 16 | 5:00PM - 7:15PM
PH and RV Failure
Room: Crestone/Red Cloud

Speaker 2 of 6
Wai Hong Wilson Tang, Cleveland Clinic, USA
What Pulmonary Hypertension and Right Heart Failure Looks like Clinically and What I Wish I Had in My Toolbox

Tuesday, January 16 | 5:00PM - 7:15PM
PH and RV Failure
Room: Crestone/Red Cloud

Speaker 3 of 6
Stephan Rosenkranz, Klinik III für Innere Medizin, Germany
Novel Targets in Pulmonary Vascular Disease and RV Dysfunction

Tuesday, January 16 | 5:00PM - 7:15PM
PH and RV Failure
Room: Crestone/Red Cloud

Speaker 4 of 6
Yibin Wang, University of California, Los Angeles, David Geffen School of Medicine, USA
Role of Stress-Signaling in Post-Natal RV Development and Maturation

Tuesday, January 16 | 5:00PM - 7:15PM
PH and RV Failure
Room: Crestone/Red Cloud

Speaker 5 of 6
Yingjie Chen, University of Minnesota, USA
Short Talk: Harnessing the T Cell Function as a New Direction in Attenuating the Transition from Left Heart Failure to Right Heart Failure through Modulating Lung Inflammation

Tuesday, January 16 | 5:00PM - 7:15PM
PH and RV Failure
Room: Crestone/Red Cloud

Speaker 6 of 6
* Edda Spiekerkoetter, Stanford University, USA
Short Talk: Increasing BMPR2 Signaling with FK506 (Tacrolimus) Reduces Cardiac Fibrosis and Improves Right Ventricular Adaptation in Pulmonary Hypertension

Tuesday, January 16 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Shavano/Torreys
No registration fees are used to fund alcohol served at this function.

Tuesday, January 16 | 7:30PM - 10:00PM
Poster Session 2
Room: Shavano/Torreys


Wednesday, January 17 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Wednesday, January 17 | 8:00AM - 11:15AM
HFrEF and Metabolism
Room: Crestone/Red Cloud

Speaker 1 of 9
* Chen Gao, University of California, Los Angeles, USA

Wednesday, January 17 | 8:00AM - 11:15AM
HFrEF and Metabolism
Room: Crestone/Red Cloud

Speaker 2 of 9
* Gemma Figtree, Kolling Institute, University of Sydney, Australia

Wednesday, January 17 | 8:00AM - 11:15AM
HFrEF and Metabolism
Room: Crestone/Red Cloud

Speaker 3 of 9
E. Dale Abel, University of Iowa, Carver College of Medicine, USA
Mitochondrial Metabolism and Signaling Mechanisms in Heart Failure

Wednesday, January 17 | 8:00AM - 11:15AM
HFrEF and Metabolism
Room: Crestone/Red Cloud

Speaker 4 of 9
Peipei Ping, University of California, Los Angeles, USA
The O-PTM Fingerprints of Mitochondrial Proteome: Molecular Signature and Functional Phenotype

Wednesday, January 17 | 8:00AM - 11:15AM
HFrEF and Metabolism
Room: Crestone/Red Cloud


Coffee Break

Wednesday, January 17 | 8:00AM - 11:15AM
HFrEF and Metabolism
Room: Crestone/Red Cloud

Speaker 6 of 9
Daniel P. Kelly, University of Pennsylvania, USA
Mitochondrial Remodeling in Heart Failure

Wednesday, January 17 | 8:00AM - 11:15AM
HFrEF and Metabolism
Room: Crestone/Red Cloud

Speaker 7 of 9
Rong Tian, University of Washington, USA
Metabolic Modulation of Cardiac Hypertrophy

Wednesday, January 17 | 8:00AM - 11:15AM
HFrEF and Metabolism
Room: Crestone/Red Cloud

Speaker 8 of 9
Jiandong Liu, University of North Carolina at Chapel Hill, USA
Short Talk: Lin28a Regulates Pathological Hypertrophic Growth through Pck2-Mediated Enhancement of Anabolic Synthesis

Wednesday, January 17 | 8:00AM - 11:15AM
HFrEF and Metabolism
Room: Crestone/Red Cloud

Speaker 9 of 9
Gregory Aubert, Loyola University, USA
Short Talk: SUR2 as a Regulator of Cardiac Metabolism Plasticity

Wednesday, January 17 | 11:15AM - 5:00PM
On Own for Lunch


Wednesday, January 17 | 11:15AM - 1:00PM
Poster Setup
Room: Shavano/Torreys


Wednesday, January 17 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys


Wednesday, January 17 | 2:30PM - 4:30PM
Workshop and Panel 3: Pharma for HF, How NOT to Get Lost in
Translation
Room: Crestone/Red Cloud

Speaker 1 of 7
* Christine E. Seidman, Harvard Medical School, USA

Wednesday, January 17 | 2:30PM - 4:30PM
Workshop and Panel 3: Pharma for HF, How NOT to Get Lost in
Translation
Room: Crestone/Red Cloud

Speaker 2 of 7
* Daria Mochly-Rosen, Stanford University, USA

Wednesday, January 17 | 2:30PM - 4:30PM
Workshop and Panel 3: Pharma for HF, How NOT to Get Lost in
Translation
Room: Crestone/Red Cloud

Speaker 3 of 7
Russell A. Miller, Pfizer Inc., USA

Wednesday, January 17 | 2:30PM - 4:30PM
Workshop and Panel 3: Pharma for HF, How NOT to Get Lost in
Translation
Room: Crestone/Red Cloud

Speaker 4 of 7
Anthony J. Muslin, Tectonic Therapeutic, Inc., USA

Wednesday, January 17 | 2:30PM - 4:30PM
Workshop and Panel 3: Pharma for HF, How NOT to Get Lost in
Translation
Room: Crestone/Red Cloud

Speaker 5 of 7
Robert N. Willette, GlaxoSmithKline, USA

Wednesday, January 17 | 2:30PM - 4:30PM
Workshop and Panel 3: Pharma for HF, How NOT to Get Lost in
Translation
Room: Crestone/Red Cloud

Speaker 6 of 7
Aarif Y. Khakoo, Amgen, USA

Wednesday, January 17 | 2:30PM - 4:30PM
Workshop and Panel 3: Pharma for HF, How NOT to Get Lost in
Translation
Room: Crestone/Red Cloud

Speaker 7 of 7
Yan G. Ni, Regeneron, USA

Wednesday, January 17 | 4:30PM - 5:00PM
Coffee Available
Room: Shavano Peak Foyer


Wednesday, January 17 | 5:00PM - 7:15PM
HFrEF: Genetics and Epigenetics
Room: Crestone/Red Cloud

Speaker 1 of 7
* Lisa Wilsbacher, Northwestern University, USA

Wednesday, January 17 | 5:00PM - 7:15PM
HFrEF: Genetics and Epigenetics
Room: Crestone/Red Cloud

Speaker 2 of 7
* Ferhaan Ahmad, University of Iowa, USA

Wednesday, January 17 | 5:00PM - 7:15PM
HFrEF: Genetics and Epigenetics
Room: Crestone/Red Cloud

Speaker 3 of 7
Elizabeth M. McNally, Northwestern University, USA
How Genetics Informs the Care of HF

Wednesday, January 17 | 5:00PM - 7:15PM
HFrEF: Genetics and Epigenetics
Room: Crestone/Red Cloud

Speaker 4 of 7
Christine E. Seidman, Harvard Medical School, USA
Genetics of Cardiomyopathy: Insights into Cardiac Physiology and Disease

Wednesday, January 17 | 5:00PM - 7:15PM
HFrEF: Genetics and Epigenetics
Room: Crestone/Red Cloud

Speaker 5 of 7
Thomas Thum, Medical School Hannover, Germany
Noncoding RNAs and Other Therapeutic Approaches in Cardiac Remodeling

Wednesday, January 17 | 5:00PM - 7:15PM
HFrEF: Genetics and Epigenetics
Room: Crestone/Red Cloud

Speaker 6 of 7
Manuel Rosa-Garrido, University of California, Los Angeles, USA
Short Talk: Elucidation of Gene Regulation Paradigms by Integrating Chromatin Architecture, Histone Marks and DNA Methylation in Failing Hearts

Wednesday, January 17 | 5:00PM - 7:15PM
HFrEF: Genetics and Epigenetics
Room: Crestone/Red Cloud

Speaker 7 of 7
Anant Chopra, Boston University, USA
Short Talk: From Tissues to Cells: Dissecting the Mechanisms of Genetic Cardiomyopathy using in vitro Engineered Disease Models

Wednesday, January 17 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Shavano/Torreys
No registration fees are used to fund alcohol served at this function.

Wednesday, January 17 | 7:30PM - 10:00PM
Poster Session 3
Room: Shavano/Torreys


Thursday, January 18 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Thursday, January 18 | 8:00AM - 9:00AM
Keynote Address
Room: Crestone/Red Cloud

Speaker 1 of 2
* Carolyn Lam, Duke-NUS Medical School, Singapore

Thursday, January 18 | 8:00AM - 9:00AM
Keynote Address
Room: Crestone/Red Cloud

Speaker 2 of 2
Daria Mochly-Rosen, Stanford University, USA
Cardiac Disease: Crossing the Translational Divide

Thursday, January 18 | 9:00AM - 11:30AM
HFpEF (Mechanisms and Therapy)
Room: Crestone/Red Cloud

Speaker 1 of 7
* Robert S. Danziger, University of Illinois at Chicago, USA

Thursday, January 18 | 9:00AM - 11:30AM
HFpEF (Mechanisms and Therapy)
Room: Crestone/Red Cloud

Speaker 2 of 7
David A. Kass, Johns Hopkins Hospital, USA
Dissecting Mechanisms of HFpEF - A Multiscale Approach

Thursday, January 18 | 9:00AM - 11:30AM
HFpEF (Mechanisms and Therapy)
Room: Crestone/Red Cloud


Coffee Break

Thursday, January 18 | 9:00AM - 11:30AM
HFpEF (Mechanisms and Therapy)
Room: Crestone/Red Cloud

Speaker 4 of 7
Carolyn Lam, Duke-NUS Medical School, Singapore
HFpEF Exists -- We Just Don’t Know What to Call It

Thursday, January 18 | 9:00AM - 11:30AM
HFpEF (Mechanisms and Therapy)
Room: Crestone/Red Cloud

Speaker 5 of 7
Wolfgang A. Linke, University of Munster, Germany
Targeting Cardiomyocyte Structure and Function in HFpEF

Thursday, January 18 | 9:00AM - 11:30AM
HFpEF (Mechanisms and Therapy)
Room: Crestone/Red Cloud

Speaker 6 of 7
Gabriele G. Schiattarella, University of Texas Southwestern Medical Center, USA
Short Talk: XBP1s-FoxO1 Axis Regulates Lipid Metabolism and Cardiac Performance in Heart Failure with Preserved Ejection Fraction

Thursday, January 18 | 9:00AM - 11:30AM
HFpEF (Mechanisms and Therapy)
Room: Crestone/Red Cloud

Speaker 7 of 7
Florin Despa, University of Kentucky, USA
Short Talk: Diabetic HFpEF in a Rat Model of Systemic Amylin Dyshomeostasis

Thursday, January 18 | 11:30AM - 5:00PM
On Own for Lunch


Thursday, January 18 | 4:30PM - 5:00PM
Coffee Available
Room: Shavano Peak Foyer


Thursday, January 18 | 5:00PM - 7:15PM
HFrEF (Cellular and Molecular Therapy)
Room: Crestone/Red Cloud

Speaker 1 of 7
* Lina A. Shehadeh, University of Miami Miller School of Medicine, USA

Thursday, January 18 | 5:00PM - 7:15PM
HFrEF (Cellular and Molecular Therapy)
Room: Crestone/Red Cloud

Speaker 2 of 7
* Lior Zangi, Icahn School of Medicine at Mount Sinai, USA

Thursday, January 18 | 5:00PM - 7:15PM
HFrEF (Cellular and Molecular Therapy)
Room: Crestone/Red Cloud

Speaker 3 of 7
Roger J. Hajjar, Mount Sinai School of Medicine, USA
Gene Therapy for Heart Failure & Pulmonary Hypertension

Thursday, January 18 | 5:00PM - 7:15PM
HFrEF (Cellular and Molecular Therapy)
Room: Crestone/Red Cloud

Speaker 4 of 7
Hesham A. Sadek, University of Texas Southwestern Medical Center, USA
Rethinking the Effect of Hypoxia on Cardiomyocytes

Thursday, January 18 | 5:00PM - 7:15PM
HFrEF (Cellular and Molecular Therapy)
Room: Crestone/Red Cloud

Speaker 5 of 7
Joseph C. Wu, Stanford University School of Medicine, USA
Genomics and Stem Cells for Precision Cardiovascular Medicine

Thursday, January 18 | 5:00PM - 7:15PM
HFrEF (Cellular and Molecular Therapy)
Room: Crestone/Red Cloud

Speaker 6 of 7
Erik A. Blackwood, San Diego State University, USA
Short Talk: Pharmacologic ATF6 Activation Reprograms Cellular Proteostasis to Mitigate Pathology in a Heart Disease Model

Thursday, January 18 | 5:00PM - 7:15PM
HFrEF (Cellular and Molecular Therapy)
Room: Crestone/Red Cloud

Speaker 7 of 7
Carmine Gentile, University of Sydney, Australia
Short Talk: Cardiac Spheroid-Based Therapy for Heart Failure Patients

Thursday, January 18 | 7:15PM - 7:30PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Crestone/Red Cloud


Thursday, January 18 | 7:30PM - 8:30PM
Social Hour with Lite Bites
Room: Shavano/Torreys
No registration fees are used to fund alcohol served at this function.

Thursday, January 18 | 8:00PM - 11:00PM
Entertainment
Room: Shavano/Torreys
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, January 18 | 8:00PM - 11:00PM
Cash Bar
Room: Shavano/Torreys


Friday, January 19 | 10:24AM - 10:24AM
Departure


*Session Chair.