Web Desc
Precision Medicine in Cancer
Organizer(s): Richard Rosenquist, Elaine Mardis and Charles M. Perou
Date: May 06 - 10, 2018
Location: Clarion Hotel Sign, Stockholm, Sweden
Organized in collaboration with Knut and Alice Wallenberg Foundation
and Science for Life Laboratory

Sponsored by Cancer Research UK, Celgene Corporation, ImmunoGen, Inc. and Thermo Fisher Scientific Inc.
For important information on the coronavirus, please click here
Summary of Meeting:
Thanks to next-generation sequencing, we have started to unravel the genomic landscape that contributes to the pathogenesis and/or evolution of several major cancer entities. For the majority of cancer subtypes, a quite diverse and complex mutation pattern is observed, with a limited number of frequently mutated genes accompanied by a long tail of genes with low-frequency mutations. Some of these genes have already been implied to have diagnostic, prognostic/predictive and even therapeutic impact, while most mutations still require functional validation. In parallel, large efforts have been made to design novel strategies targeting key cellular pathways and processes, which in turn has led to introduction of targeted therapy in selected entities. However, there is still a gap-of-knowledge and urgent medical need to determine how to combine the genetic information with risk-stratification and treatment algorithms in the individual patient, i.e., precision medicine. This symposium will highlight large-scale sequencing efforts carried out in different cancer types, including both solid tumors and hematological malignancies, which have paved the way for the incorporation of next-generation sequencing-based approaches into routine clinical diagnostics and every-day patient care. The conference will encompass the rapidly evolving field of disease monitoring by ultra-sensitive sequencing of tumor-specific mutations, as well as introduce novel approaches and other omics technologies and functional studies that will aid future efforts in precision medicine. Finally, successful examples of how genomic findings have spurred development of targeted therapies will be presented. In summary, the symposium will bring together basic scientists, translational researchers and clinicians to meet and discuss concerted action toward precision medicine in cancer.
Scholarship Deadline: January 9 2018
Discounted Abstract Deadline: January 9 2018
Abstract Deadline: February 6 2018
Discounted Registration Deadline: March 6 2018
Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.


Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Cancer Research UKThis activity was supported by an educational grant from Celgene CorporationImmunoGen, Inc.Science for Life LaboratoryThermo Fisher Scientific Inc.Knut and Alice Wallenberg Foundation
We gratefully acknowledge additional support for this conference from:
American Association for Cancer Research (AACR)
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, May 06 | 4:00PM - 8:00PM
Arrival and Registration
Room: Foyer


Sunday, May 06 | 6:00PM - 8:00PM
Welcome Mixer
Room: Foyer
No registration fees are used to fund alcohol served at this function.

Monday, May 07 | 8:00AM - 8:30AM
Poster Setup
Room: B 3


Monday, May 07 | 8:30AM - 5:00PM
Poster Viewing
Room: B 3


Monday, May 07 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: B 1-2

Speaker 1 of 3
* Elaine R. Mardis, Nationwide Children's Hospital, USA

Monday, May 07 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: B 1-2

Speaker 2 of 3
* Richard Rosenquist, Karolinska Institutet, Sweden

Monday, May 07 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: B 1-2

Speaker 3 of 3
* Charles M. Perou, University of North Carolina at Chapel Hill, USA
Charting the Cancer Genome Landscape: Lessons, Opportunities and Challenges

Monday, May 07 | 9:30AM - 12:15PM
Clinical Genomics in Solid Tumors
Room: B 1-2

Speaker 1 of 5
* Elaine R. Mardis, Nationwide Children's Hospital, USA

Monday, May 07 | 9:30AM - 12:15PM
Clinical Genomics in Solid Tumors
Room: B 1-2

Speaker 2 of 5
Serena Nik-Zainal, University of Cambridge, UK
Landscape of Somatic Mutations in Breast Cancer: Clinical Implications

Monday, May 07 | 9:30AM - 12:15PM
Clinical Genomics in Solid Tumors
Room: B 1-2


Coffee Break

Monday, May 07 | 9:30AM - 12:15PM
Clinical Genomics in Solid Tumors
Room: B 1-2

Speaker 4 of 5
Dan Robinson, University of Michigan, USA
Integrative Clinical Genomics of Advanced Cancer

Monday, May 07 | 9:30AM - 12:15PM
Clinical Genomics in Solid Tumors
Room: B 1-2

Speaker 5 of 5
Charles Swanton, Francis Crick Institute, UK
Cancer Evolution and Immune Escape: TRACERx


Monday, May 07 | 12:15PM - 12:45PM
Lunch
Room: B3/Atrium


Monday, May 07 | 12:15PM - 2:30PM
Poster Session 1
Room: B 3


Monday, May 07 | 2:30PM - 4:30PM
Workshop 1: Deciphering Cancer by Next-Generation Sequencing
Room: B 1-2

Speaker 1 of 8
* Lillian L. Siu, Princess Margaret Hospital, Canada

Monday, May 07 | 2:30PM - 4:30PM
Workshop 1: Deciphering Cancer by Next-Generation Sequencing
Room: B 1-2

Speaker 2 of 8
Emelie Berglund, KTH-Royal Institute of Technology, Sweden
Spatial Transcriptomics Analysis of Castration-Resistant Prostate Cancer

Monday, May 07 | 2:30PM - 4:30PM
Workshop 1: Deciphering Cancer by Next-Generation Sequencing
Room: B 1-2

Speaker 3 of 8
Mark A. Rubin, University of Bern, Switzerland
Swiss Oncology and Cancer Immunology Breakthrough Platform (SOCIBP) for Precision Oncology

Monday, May 07 | 2:30PM - 4:30PM
Workshop 1: Deciphering Cancer by Next-Generation Sequencing
Room: B 1-2

Speaker 4 of 8
Katie Campbell, University of California, Los Angeles, USA
Comprehensive Genomics Elucidate Class I-Specific Responses due to Pembrolizumab in Treatment-Naive HNSCC

Monday, May 07 | 2:30PM - 4:30PM
Workshop 1: Deciphering Cancer by Next-Generation Sequencing
Room: B 1-2

Speaker 5 of 8
Bojan Losic, Icahn School of Medicine at Sinai, USA
Immuno-Genomic View of Intra-Tumoral Heterogeneity in Liver Cancer

Monday, May 07 | 2:30PM - 4:30PM
Workshop 1: Deciphering Cancer by Next-Generation Sequencing
Room: B 1-2

Speaker 6 of 8
Alex J. Gooding, Case Western Reserve University, USA
Novel lncRNA BORG Predicts for Metastatic Relapse and Chemoresistance in Triple-Negative Breast Cancer

Monday, May 07 | 2:30PM - 4:30PM
Workshop 1: Deciphering Cancer by Next-Generation Sequencing
Room: B 1-2

Speaker 7 of 8
Christian Brueffer, Lund University, Sweden
RNA-seq-Based Classifiers for Prediction of the Five Conventional Breast Cancer Biomarkers in the Population-Based Multicenter SCAN-B Study

Monday, May 07 | 2:30PM - 4:30PM
Workshop 1: Deciphering Cancer by Next-Generation Sequencing
Room: B 1-2

Speaker 8 of 8
Noam Auslander, NIH, USA
Robust Prediction of Therapeutic Response to Immune Checkpoint Blockade Therapy in Metastatic Melanoma

Monday, May 07 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Monday, May 07 | 5:00PM - 7:00PM
Precision Diagnostics in Solid Tumors
Room: B 1-2

Speaker 1 of 4
* Charles M. Perou, University of North Carolina at Chapel Hill, USA

Monday, May 07 | 5:00PM - 7:00PM
Precision Diagnostics in Solid Tumors
Room: B 1-2

Speaker 2 of 4
Michael F. Berger, Memorial Sloan Kettering Cancer Center, USA
Integrated Genomic Assays for Precision Cancer Diagnostics

Monday, May 07 | 5:00PM - 7:00PM
Precision Diagnostics in Solid Tumors
Room: B 1-2

Speaker 3 of 4
Lillian L. Siu, Princess Margaret Hospital, Canada
A Decade of Precision Medicine: Reality or Myth?

Monday, May 07 | 5:00PM - 7:00PM
Precision Diagnostics in Solid Tumors
Room: B 1-2

Speaker 4 of 4
Matthew J. Ellis, Baylor College of Medicine, USA
Integrated Proteogenomics for Biomarker Discovery in Breast Cancer

Monday, May 07 | 7:00PM - 7:00PM
On Own for Dinner


Tuesday, May 08 | 8:30AM - 9:30AM
Keynote Address
Room: B 1-2

Speaker 1 of 2
* Richard Rosenquist, Karolinska Institutet, Sweden

Tuesday, May 08 | 8:30AM - 9:30AM
Keynote Address
Room: B 1-2

Speaker 2 of 2
Elaine R. Mardis, Nationwide Children's Hospital, USA
Clinical Cancer Genomics in the Diagnosis of Pediatric CNS Tumors

Tuesday, May 08 | 9:30AM - 12:15PM
Clinical Genomics in Hematological Malignancies
Room: B 1-2

Speaker 1 of 6
* Catherine J. Wu, Dana-Farber Cancer Institute, USA

Tuesday, May 08 | 9:30AM - 12:15PM
Clinical Genomics in Hematological Malignancies
Room: B 1-2

Speaker 2 of 6
Charles G. Mullighan, St. Jude Children's Research Hospital, USA
Advances in Genetics and Therapy in Pediatric Acute Lymphoblastic Leukemia

Tuesday, May 08 | 9:30AM - 12:15PM
Clinical Genomics in Hematological Malignancies
Room: B 1-2


Coffee Break

Tuesday, May 08 | 9:30AM - 12:15PM
Clinical Genomics in Hematological Malignancies
Room: B 1-2

Speaker 4 of 6
Richard Rosenquist, Karolinska Institutet, Sweden
The Molecular Landscape of Chronic Lymphocytic Leukemia: Prognostic and Therapeutic Implications

Tuesday, May 08 | 9:30AM - 12:15PM
Clinical Genomics in Hematological Malignancies
Room: B 1-2

Speaker 5 of 6
Riccardo Dalla-Favera, Columbia University, USA
Genomics of Diffuse Large B Cell Lymphoma

Tuesday, May 08 | 9:30AM - 12:15PM
Clinical Genomics in Hematological Malignancies
Room: B 1-2

Speaker 6 of 6
Elli Papaemmanuil, Memorial Sloan Kettering Cancer Center, USA
Genomic Drivers and Prognosis in Acute Myeloid Leukemia

Tuesday, May 08 | 12:15PM - 5:00PM
On Own for Lunch


Tuesday, May 08 | 12:15PM - 1:00PM
Poster Setup
Room: B 3


Tuesday, May 08 | 1:00PM - 10:00PM
Poster Viewing
Room: B 3


Tuesday, May 08 | 2:30PM - 4:30PM
Workshop 2: Circulating Cell-Free Nucleic Acid Sequencing an
d Detection of Minimal Residual Disease
Room: B 1-2

Speaker 1 of 8
* Elli Papaemmanuil, Memorial Sloan Kettering Cancer Center, USA

Tuesday, May 08 | 2:30PM - 4:30PM
Workshop 2: Circulating Cell-Free Nucleic Acid Sequencing an
d Detection of Minimal Residual Disease
Room: B 1-2

Speaker 2 of 8
Adrian V. Lee, University of Pittsburgh, USA
Targeted Mutation Detection from Fingerstick Capillary Blood using a Breast Cancer-Specific Panel MammaSeq

Tuesday, May 08 | 2:30PM - 4:30PM
Workshop 2: Circulating Cell-Free Nucleic Acid Sequencing an
d Detection of Minimal Residual Disease
Room: B 1-2

Speaker 3 of 8
Celine Everaert, Ghent University, Belgium
Pan-Cancer Identification of Noncoding RNAs with Biomarker Potential in Plasma

Tuesday, May 08 | 2:30PM - 4:30PM
Workshop 2: Circulating Cell-Free Nucleic Acid Sequencing an
d Detection of Minimal Residual Disease
Room: B 1-2

Speaker 4 of 8
Laura W. Dillon, NHLBI, National Institutes of Health, USA
Targeted RNA-Sequencing for the Quantification of Measurable Residual Disease in Acute Myeloid Leukemia

Tuesday, May 08 | 2:30PM - 4:30PM
Workshop 2: Circulating Cell-Free Nucleic Acid Sequencing an
d Detection of Minimal Residual Disease
Room: B 1-2

Speaker 5 of 8
Louise Pettersson, Lund University, Sweden
Monitoring Leukemic Mutations Using Ultrasensitive IBSAFE Digital Droplet Analysis Predicts Relapse of Acute Myeloid Leukemia

Tuesday, May 08 | 2:30PM - 4:30PM
Workshop 2: Circulating Cell-Free Nucleic Acid Sequencing an
d Detection of Minimal Residual Disease
Room: B 1-2

Speaker 6 of 8
Renate Slind Olsen, County Hospital Ryhov, Sweden
Circulating Inflammatory Factors Associated with Worse Long-Term Prognosis in Colorectal Cancer

Tuesday, May 08 | 2:30PM - 4:30PM
Workshop 2: Circulating Cell-Free Nucleic Acid Sequencing an
d Detection of Minimal Residual Disease
Room: B 1-2

Speaker 7 of 8
Jennifer C. Jones, NCI, National Institutes of Health, USA
Development of an Exosome Analysis Pipeline for Precision Oncology

Tuesday, May 08 | 2:30PM - 4:30PM
Workshop 2: Circulating Cell-Free Nucleic Acid Sequencing an
d Detection of Minimal Residual Disease
Room: B 1-2

Speaker 8 of 8
Johan Lindberg, Karolinska Institutet, Sweden
Cell-Free DNA Profiling of Metastatic Prostate Cancer Reveals Microsatellite Instability, Structural Rearrangements and Clonal Hematopoiesis

Tuesday, May 08 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Tuesday, May 08 | 5:00PM - 7:00PM
Precision Diagnostics in Hematological Malignancies
Room: B 1-2

Speaker 1 of 6
* Richard Rosenquist, Karolinska Institutet, Sweden

Tuesday, May 08 | 5:00PM - 7:00PM
Precision Diagnostics in Hematological Malignancies
Room: B 1-2

Speaker 2 of 6
Maria Luisa Sulis, Columbia University Medical Center, USA
Clinical Implementation of Sequencing in Pediatric Hematology-Oncology Practice

Tuesday, May 08 | 5:00PM - 7:00PM
Precision Diagnostics in Hematological Malignancies
Room: B 1-2

Speaker 3 of 6
Yanara Marincevic-Zuniga, Uppsala University, Sweden
Short Talk: DNA Methylation Classification Combined with RNA-Sequencing for Subtype Discovery in Pediatric Acute Lymphoblastic Leukemia

Tuesday, May 08 | 5:00PM - 7:00PM
Precision Diagnostics in Hematological Malignancies
Room: B 1-2

Speaker 4 of 6
Mei Wang, Karolinska Institutet, China
Short Talk: RNA Sequencing-Based Prognostic Score Outperforms Conventional Prognostic Scores in Acute Myeloid Leukemia (AML)

Tuesday, May 08 | 5:00PM - 7:00PM
Precision Diagnostics in Hematological Malignancies
Room: B 1-2

Speaker 5 of 6
Sylvain Mareschal, Karolinska Institutet, Sweden
Short Talk: Next-Generation Karyotyping in Acute Myeloid Leukemia

Tuesday, May 08 | 5:00PM - 7:00PM
Precision Diagnostics in Hematological Malignancies
Room: B 1-2

Speaker 6 of 6
Jing Xu, German Cancer Research Center, Germany
Short Talk: Signaling Pathway Profiling in Multiple Myeloma

Tuesday, May 08 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: B3/Atrium
No registration fees are used to fund alcohol served at this function.

Tuesday, May 08 | 7:30PM - 10:00PM
Poster Session 2
Room: B 3


Wednesday, May 09 | 8:30AM - 11:45AM
Disease Monitoring in Cancer Patients
Room: B 1-2

Speaker 1 of 8
* Adrian V. Lee, University of Pittsburgh, USA

Wednesday, May 09 | 8:30AM - 11:45AM
Disease Monitoring in Cancer Patients
Room: B 1-2

Speaker 2 of 8
Catherine Alix-Panabières, University Medical Centre, France
Functional Analyses of CTCs in Cancer Patients

Wednesday, May 09 | 8:30AM - 11:45AM
Disease Monitoring in Cancer Patients
Room: B 1-2

Speaker 3 of 8
Alberto Bardelli, University of Torino, Italy
Cancer Evolution as a Therapeutic Target

Wednesday, May 09 | 8:30AM - 11:45AM
Disease Monitoring in Cancer Patients
Room: B 1-2


Coffee Break

Wednesday, May 09 | 8:30AM - 11:45AM
Disease Monitoring in Cancer Patients
Room: B 1-2

Speaker 5 of 8
Eva Hellström-Lindberg, Karolinska Institutet, Sweden
High-Throughput Mutational Screening Improves Risk Stratification in Myelodysplastic Syndromes

Wednesday, May 09 | 8:30AM - 11:45AM
Disease Monitoring in Cancer Patients
Room: B 1-2

Speaker 6 of 8
Catherine J. Wu, Dana-Farber Cancer Institute, USA
Intraclonal Dynamics in Chronic Lymphocytic Leukemia


Wednesday, May 09 | 8:30AM - 11:45AM
Disease Monitoring in Cancer Patients
Room: B 1-2

Speaker 7 of 8
Suresh K. Alahari, Louisiana State University Health Sciences Center, USA
Short Talk: Utilization of MicroRNAs in the Era of Personalized Medicine

Wednesday, May 09 | 8:30AM - 11:45AM
Disease Monitoring in Cancer Patients
Room: B 1-2

Speaker 8 of 8
Shumaila Sayyab, Uppsala University, Sweden
Short Talk: Clonal Evolution of Acute Lymphoblastic Leukemia Cells from Diagnosis to Relapse

Wednesday, May 09 | 11:45AM - 5:00PM
On Own for Lunch


Wednesday, May 09 | 11:45AM - 1:00PM
Poster Setup
Room: B 3


Wednesday, May 09 | 12:00PM - 2:15PM
SciLifeLab Lunch Seminar: Cutting-Edge Technologies in Preci
sion Cancer Medicine (Must Register in Advance)
Room: C12
Register here to secure your lunch. There will also be an opportunity to register for the seminar on site at Clarion Hotel Sign, however we will not be able to offer you lunch.

More information about the program and registration: https://www.scilifelab.se/scilifelab-lunch-seminar-cutting-edge-technologies-in-precision-cancer-medicine


Wednesday, May 09 | 1:00PM - 10:00PM
Poster Viewing
Room: B 3


Wednesday, May 09 | 2:15PM - 3:30PM
Mingle with SciLifeLab


Wednesday, May 09 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Wednesday, May 09 | 5:00PM - 7:00PM
Novel Approaches in Cancer Genomics
Room: B 1-2

Speaker 1 of 6
* Matthew J. Ellis, Baylor College of Medicine, USA

Wednesday, May 09 | 5:00PM - 7:00PM
Novel Approaches in Cancer Genomics
Room: B 1-2

Speaker 2 of 6
David T. Miyamoto, Massachusetts General Hospital, USA
Molecular Characterization of Circulating Tumor Cells for Precision Cancer Medicine

Wednesday, May 09 | 5:00PM - 7:00PM
Novel Approaches in Cancer Genomics
Room: B 1-2

Speaker 3 of 6
Olli Kallioniemi, Science for Life Laboratory, Sweden
Precision Systems Medicine to Tailor Cancer Treatments

Wednesday, May 09 | 5:00PM - 7:00PM
Novel Approaches in Cancer Genomics
Room: B 1-2

Speaker 4 of 6
Jeroen Roose, University of California, San Francisco, USA
Short Talk: Predicting Synthetic Lethality in the Context of PI3 Kinase Inhibition with High Fidelity

Wednesday, May 09 | 5:00PM - 7:00PM
Novel Approaches in Cancer Genomics
Room: B 1-2

Speaker 5 of 6
Arvind Singh Mer, University of Toronto, Canada
Short Talk: Systematic Identification of Genomic Predictors for Anticancer Drug Sensitivity in Patient-Derived Xenografts

Wednesday, May 09 | 5:00PM - 7:00PM
Novel Approaches in Cancer Genomics
Room: B 1-2

Speaker 6 of 6
Päivi Östling, Science for Life Laboratory, Karolinska Institutet, Sweden
Short Talk: Precision Systems Medicine in Urological Tumors - Molecular Profiling and Functional Testing

Wednesday, May 09 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: B3/Atrium
No registration fees are used to fund alcohol served at this function.

Wednesday, May 09 | 7:30PM - 10:00PM
Poster Session 3
Room: B 3


Thursday, May 10 | 8:30AM - 11:30AM
Novel Targets, Novel Therapies I
Room: B 1-2

Speaker 1 of 7
* Olli Kallioniemi, Science for Life Laboratory, Sweden

Thursday, May 10 | 8:30AM - 11:30AM
Novel Targets, Novel Therapies I
Room: B 1-2

Speaker 2 of 7
Gerald P. Linette, University of Pennsylvania, USA
Melanoma Neoantigen Discovery and Clinical Validation


Thursday, May 10 | 8:30AM - 11:30AM
Novel Targets, Novel Therapies I
Room: B 1-2

Speaker 3 of 7
Winette T. Van Der Graaf, Institute of Cancer Research, UK
Targeting the Kinome in Cancer: The Need for Return Tickets from Bench to Bedside,
Exemplified by the Progress in Understanding Gastrointestinal Stromal Tumors (GIST)


Thursday, May 10 | 8:30AM - 11:30AM
Novel Targets, Novel Therapies I
Room: B 1-2


Coffee Break

Thursday, May 10 | 8:30AM - 11:30AM
Novel Targets, Novel Therapies I
Room: B 1-2

Speaker 5 of 7
Kenna Rael Mills Shaw, University of Texas, MD Anderson Cancer Center, USA
Precision Cancer Medicine: Neither Silver Bullet Nor an Illusion

Thursday, May 10 | 8:30AM - 11:30AM
Novel Targets, Novel Therapies I
Room: B 1-2

Speaker 6 of 7
Thomas Helleday, Karolinska Institutet, Sweden
Targeting the DNA Damage Response in Cancer

Thursday, May 10 | 8:30AM - 11:30AM
Novel Targets, Novel Therapies I
Room: B 1-2

Speaker 7 of 7
Ron S. Gejman, Memorial Sloan Kettering Cancer Center, USA
Short Talk: The Ability of T Cell Antigens to Cause Tumor Cell Rejection Is Dependent on Tumor Cell Subclone Frequency

Thursday, May 10 | 11:30AM - 5:00PM
On Own for Lunch


Thursday, May 10 | 2:30PM - 4:30PM
Workshop 3: Identifying Novel Targets and Therapies
Room: B 1-2

Speaker 1 of 8
* Laurence Zitvogel, Institut Gustave Roussy, France

Thursday, May 10 | 2:30PM - 4:30PM
Workshop 3: Identifying Novel Targets and Therapies
Room: B 1-2

Speaker 2 of 8
Eva Marina Schmidt, Ludwig-Maximillians-Universität München, Germany
Therapeutic Targeting of Tumor Heterogeneity by Inhibition of MAPK and NOTCH Signaling in Colorectal Cancer

Thursday, May 10 | 2:30PM - 4:30PM
Workshop 3: Identifying Novel Targets and Therapies
Room: B 1-2

Speaker 3 of 8
Alexandre Couture, Normandy University, France
New Cancer Immunotherapy Strategies Based on the Use of Artificial Antigen-Presenting Cells for Activating Potent Anti-Tumor Specific CD4+ T Lymphocytes

Thursday, May 10 | 2:30PM - 4:30PM
Workshop 3: Identifying Novel Targets and Therapies
Room: B 1-2

Speaker 4 of 8
Catríona M. Dowling, Royal College of Surgeons in Ireland, Ireland
Discovery of a Novel Histone Deacetylase 6 Inhibitor that Kills Drug-Resistant Breast Cancer

Thursday, May 10 | 2:30PM - 4:30PM
Workshop 3: Identifying Novel Targets and Therapies
Room: B 1-2

Speaker 5 of 8
Purusottam Mohapatra, University of Lund, Sweden
WNT5A-IL-6 Signaling as a Therapeutic Target in Melanoma

Thursday, May 10 | 2:30PM - 4:30PM
Workshop 3: Identifying Novel Targets and Therapies
Room: B 1-2

Speaker 6 of 8
Arthur L. Shaffer III, NCI, National Institutes of Health, USA
Ibrutinib Resistance in Diffuse Large B cell Lymphoma: Evolution, Novel Dependencies and Therapeutic Options

Thursday, May 10 | 2:30PM - 4:30PM
Workshop 3: Identifying Novel Targets and Therapies
Room: B 1-2

Speaker 7 of 8
Göran Jönsson, Lund University, Sweden
Comprehensive Genomic Analysis Predict Clinical Benefit of Adoptive T Cell Therapy in Melanoma

Thursday, May 10 | 2:30PM - 4:30PM
Workshop 3: Identifying Novel Targets and Therapies
Room: B 1-2

Speaker 8 of 8
Yardena Samuels, Weizmann Institute of Science, Israel
UVB-Induced Genomic Alterations Dictates Anti-Tumor Immune Response against Melanoma

Thursday, May 10 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Thursday, May 10 | 5:00PM - 6:45PM
Novel Targets, Novel Therapies II
Room: B 1-2

Speaker 1 of 4
* Kenna Rael Mills Shaw, University of Texas, MD Anderson Cancer Center, USA

Thursday, May 10 | 5:00PM - 6:45PM
Novel Targets, Novel Therapies II
Room: B 1-2

Speaker 2 of 4
Renier Brentjens, Memorial Sloan Kettering Cancer Center, USA
Talk Title to be Announced

Thursday, May 10 | 5:00PM - 6:45PM
Novel Targets, Novel Therapies II
Room: B 1-2

Speaker 3 of 4
Eric Tran, Providence Cancer Institute, USA
Immunogenicity and Immunotherapeutic Targeting of Mutated Neoantigens in Human Cancer

Thursday, May 10 | 5:00PM - 6:45PM
Novel Targets, Novel Therapies II
Room: B 1-2

Speaker 4 of 4
Laurence Zitvogel, Institut Gustave Roussy, France
Resistance to Immune-Checkpoint Blockade in Cancer

Thursday, May 10 | 6:45PM - 7:15PM
Closing Remarks
Room: B 1-2

Speaker 1 of 1
* Jonas Bergh, Karolinska Institutet, Sweden
A Clinical Oncologist's Perspective

Thursday, May 10 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: B3/Atrium
No registration fees are used to fund alcohol served at this function.

Thursday, May 10 | 8:00PM - 11:00PM
Entertainment
Room: B 3
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, May 10 | 8:00PM - 11:00PM
Cash Bar
Room: B 3


Friday, May 11 | 10:24AM - 10:24AM
Departure


*Session Chair
†Invited, not yet responded.