Web Desc
Frontiers of Serotonin Beyond the Brain
Organizer(s): Fusun Kilic, Michael D. Gershon and Luc Maroteaux
Date: November 12 - 15, 2017
Location: Doubletree by Hilton - Park City, Park City, UT, USA
Supported by the Directors' Fund
Summary of Meeting:
Serotonin is a multifunctional signaling molecule that plays extra-cerebral roles, not only in adult life but in development as well. Although research concerning extra-cerebral serotonin is growing rapidly and interest in the subject is great, the physiological control and underlying molecular processes, as well as the involvement of peripheral serotonin in disease, have not been definitively established. Furthermore, the role of serotonin in peripheral tissues, has been neglected and under-represented at current meetings, which have focused on the 3-5% of the body’s serotonin that is present in the central nervous system. Therefore, this Keystone Symposia meeting aims to reveal insights into the role of serotonin in peripheral tissues, specifically in the diagnosis, prevention and treatment of many diseases, which is long overdue.
Scholarship Deadline: July 11 2017
Discounted Abstract Deadline: July 11 2017
Abstract Deadline: August 10 2017
Discounted Registration Deadline: September 12 2017
We gratefully acknowledge additional support for this conference from:
Chroma Technology CorporationOncotarget
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, November 12 | 4:00PM - 8:00PM
Arrival and Registration
Room: Main Hotel Lobby


Sunday, November 12 | 6:00PM - 8:00PM
Welcome Mixer
Room: Vertical Lounge
No registration fees are used to fund alcohol served at this function.

Monday, November 13 | 7:30AM - 8:30AM
Breakfast
Room: Summit B & C


Monday, November 13 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Summit A

Speaker 1 of 2
* Fusun Kilic, Merced College, USA

Monday, November 13 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Summit A

Speaker 2 of 2
Michael D. Gershon, Columbia University, USA
Serotonergic Regulation of Enteric Neurogenesis

Monday, November 13 | 9:30AM - 12:00PM
Serotonin, a Major Peripheral Neurohormone
Room: Summit A

Speaker 1 of 7
* Fusun Kilic, Merced College, USA

Monday, November 13 | 9:30AM - 12:00PM
Serotonin, a Major Peripheral Neurohormone
Room: Summit A

Speaker 2 of 7
Elaine Y. Hsiao, University of California, Los Angeles, USA
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

Monday, November 13 | 9:30AM - 12:00PM
Serotonin, a Major Peripheral Neurohormone
Room: Summit A


Coffee Break

Monday, November 13 | 9:30AM - 12:00PM
Serotonin, a Major Peripheral Neurohormone
Room: Summit A

Speaker 4 of 7
Gary M. Mawe, University of Vermont, USA
Mucosal Serotonin Signaling in the Gut: Changes in Disease and Therapeutic Targets


Monday, November 13 | 9:30AM - 12:00PM
Serotonin, a Major Peripheral Neurohormone
Room: Summit A

Speaker 5 of 7
Nick J. Spencer, Flinders University, Australia
Is There a Role for Mucosal Serotonin in the Generation of Neurogenic Motor Patterns in the Gut Wall?

Monday, November 13 | 9:30AM - 12:00PM
Serotonin, a Major Peripheral Neurohormone
Room: Summit A

Speaker 6 of 7
Supriya Srinivasan, The Scripps Research Institute, USA
Short Talk: Serotonergic Orchestration of Energy Balance: Translating Insights and New Pathways from Caenorhabditis elegans

Monday, November 13 | 9:30AM - 12:00PM
Serotonin, a Major Peripheral Neurohormone
Room: Summit A

Speaker 7 of 7
Natalia Alenina, Max Delbrück Center for Molecular Medicine, Germany
Short Talk: Reevaluation of Serotonin Synthesis Pathways: Phenylalanine Hydroxylase as an Alternative Source of Peripheral Serotonin

Monday, November 13 | 12:00PM - 5:00PM
On Own for Lunch


Monday, November 13 | 12:00PM - 1:00PM
Poster Setup
Room: Summit B & C


Monday, November 13 | 1:00PM - 10:00PM
Poster Viewing
Room: Summit B & C


Monday, November 13 | 4:30PM - 5:00PM
Coffee Available
Room: Summit Foyer


Monday, November 13 | 5:00PM - 7:00PM
Serotonin in a New Drug Target
Room: Summit A

Speaker 1 of 5
* Michael D. Gershon, Columbia University, USA

Monday, November 13 | 5:00PM - 7:00PM
Serotonin in a New Drug Target
Room: Summit A

Speaker 2 of 5
Gerard Karsenty, Columbia University Medical Center, USA
Serotonin in a New Drug Target

Monday, November 13 | 5:00PM - 7:00PM
Serotonin in a New Drug Target
Room: Summit A

Speaker 3 of 5
Suman Wason, Lexicon Pharmaceuticals, Inc., USA
Tryptophan Hydroxylase Inhibitors for Carcinoid Syndrome

Monday, November 13 | 5:00PM - 7:00PM
Serotonin in a New Drug Target
Room: Summit A

Speaker 4 of 5
Michael Bader, Max Delbrück Center for Molecular Medicine, Germany
Peripheral Serotonin, a New Drug Target

Monday, November 13 | 5:00PM - 7:00PM
Serotonin in a New Drug Target
Room: Summit A

Speaker 5 of 5
Mari Lilith Lund, University of Copenhagen, Denmark
Short Talk: Serotonin-Producing Enterochromaffin Cells Are a Major Target for GLP-1 in the Gastrointestinal Tract

Monday, November 13 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Summit B & C
No registration fees are used to fund alcohol served at this function.

Monday, November 13 | 7:30PM - 10:00PM
Poster Session 1
Room: Summit B & C


Tuesday, November 14 | 7:30AM - 8:30AM
Breakfast
Room: Summit B & C


Tuesday, November 14 | 8:30AM - 9:30AM
Keynote Address
Room: Summit A

Speaker 1 of 2
* Laurent Monassier, Université de Strasbourg, France

Tuesday, November 14 | 8:30AM - 9:30AM
Keynote Address
Room: Summit A

Speaker 2 of 2
Stephanie Wengert Watts, Michigan State University, USA
5-HT and Blood Pressure: Knowing and Learning


Tuesday, November 14 | 9:30AM - 11:45AM
Serotonin in the Circulatory System
Room: Summit A

Speaker 1 of 6
* Laurent Monassier, Université de Strasbourg, France

Tuesday, November 14 | 9:30AM - 11:45AM
Serotonin in the Circulatory System
Room: Summit A

Speaker 2 of 6
Francine Côté, INSERM, France
Bone Marrow-Derived Serotonin Regulates Expansion of Red Blood Cell Progenitors

Tuesday, November 14 | 9:30AM - 11:45AM
Serotonin in the Circulatory System
Room: Summit A


Coffee Break

Tuesday, November 14 | 9:30AM - 11:45AM
Serotonin in the Circulatory System
Room: Summit A

Speaker 4 of 6
Harvey J. Kliman, Yale University, USA
The Serotonin Highway in the Human Placenta: Serotonin Transport from Mother to Fetus

Tuesday, November 14 | 9:30AM - 11:45AM
Serotonin in the Circulatory System
Room: Summit A

Speaker 5 of 6
Fusun Kilic, Merced College, USA
Serotonin Transporter in Platelets and Placenta

Tuesday, November 14 | 9:30AM - 11:45AM
Serotonin in the Circulatory System
Room: Summit A

Speaker 6 of 6
Yahan Liu, Peking University Health Science Center, China
Short Talk: 5-HT2BR Promoted Vascular Restenosis via ß-arrestin2-mTOR/p70S6K Pathway

Tuesday, November 14 | 11:45AM - 5:00PM
On Own for Lunch


Tuesday, November 14 | 1:00PM - 10:00PM
Poster Viewing
Room: Summit B & C


Tuesday, November 14 | 4:30PM - 5:00PM
Coffee Available
Room: Summit Foyer


Tuesday, November 14 | 5:00PM - 7:00PM
Serotonin Receptors in Cardiovascular and Pulmonary Function
s

Room: Summit A

Speaker 1 of 4
* Stephanie Wengert Watts, Michigan State University, USA

Tuesday, November 14 | 5:00PM - 7:00PM
Serotonin Receptors in Cardiovascular and Pulmonary Function
s

Room: Summit A

Speaker 2 of 4
Laurent Monassier, Université de Strasbourg, France
Heart Disease and Valvulopathy


Tuesday, November 14 | 5:00PM - 7:00PM
Serotonin Receptors in Cardiovascular and Pulmonary Function
s

Room: Summit A

Speaker 3 of 4
Luc Maroteaux, INSERM UMR-S 839 / Université Pierre et Marie Curie (UPMC), France
Serotonin Receptor Signaling in Development

Tuesday, November 14 | 5:00PM - 7:00PM
Serotonin Receptors in Cardiovascular and Pulmonary Function
s

Room: Summit A

Speaker 4 of 4
Kevin Currie, Cooper Medical School of Rowan University, USA
Peripheral Serotonin and Control of the Sympathoadrenal Stress Response

Tuesday, November 14 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Summit B & C
No registration fees are used to fund alcohol served at this function.

Wednesday, November 15 | 7:30AM - 8:30AM
Breakfast
Room: Summit B & C


Wednesday, November 15 | 8:30AM - 11:30AM
Peripheral Serotonin in Relation to Brain Function and Devel
opment

Room: Summit A

Speaker 1 of 7
* Luc Maroteaux, INSERM UMR-S 839 / Université Pierre et Marie Curie (UPMC), France

Wednesday, November 15 | 8:30AM - 11:30AM
Peripheral Serotonin in Relation to Brain Function and Devel
opment

Room: Summit A

Speaker 2 of 7
Kara Gross Margolis, NewYork-Presbyterian Morgan Stanley Children's Hospital, USA
The Involvement of Peripheral Serotonin in Autism

Wednesday, November 15 | 8:30AM - 11:30AM
Peripheral Serotonin in Relation to Brain Function and Devel
opment

Room: Summit A

Speaker 3 of 7
Randy Blakely, Florida Atlantic University, USA
Keeping the Periphery in Mind: Peripheral Inflammatory Modulation of Behavior Mediated by CNS Serotonin

Wednesday, November 15 | 8:30AM - 11:30AM
Peripheral Serotonin in Relation to Brain Function and Devel
opment

Room: Summit A


Coffee Break

Wednesday, November 15 | 8:30AM - 11:30AM
Peripheral Serotonin in Relation to Brain Function and Devel
opment

Room: Summit A

Speaker 5 of 7
Alexandre Bonnin, University of Southern California, USA
Prenatal Exposures and Placental Serotonin: a Pathway for the Fetal Programming of Mental Disorders

Wednesday, November 15 | 8:30AM - 11:30AM
Peripheral Serotonin in Relation to Brain Function and Devel
opment

Room: Summit A

Speaker 6 of 7
Hail Kim, Korea Advanced Institute of Science and Technology, South Korea
Regulation of Systemic Energy Homeostasis by Peripheral Serotonin

Wednesday, November 15 | 8:30AM - 11:30AM
Peripheral Serotonin in Relation to Brain Function and Devel
opment

Room: Summit A

Speaker 7 of 7
Jeremy M. Veenstra-VanderWeele, Columbia University and New York State Psychiatric Institute, USA
Short Talk: Maternal Whole Blood Serotonin Levels Are Associated with Cognitive Ability and Core Symptoms in Children with Autism Spectrum Disorder

Wednesday, November 15 | 11:30AM - 5:00PM
On Own for Lunch


Wednesday, November 15 | 4:30PM - 5:00PM
Coffee Available
Room: Summit Foyer


Wednesday, November 15 | 5:00PM - 6:45PM
Serotonin in Diseases
Room: Summit A

Speaker 1 of 4
* Michael Bader, Max Delbrück Center for Molecular Medicine, Germany

Wednesday, November 15 | 5:00PM - 6:45PM
Serotonin in Diseases
Room: Summit A

Speaker 2 of 4
Joanne Wang, University of Washington, USA
Serotonin Transporter Deficiency Drives Estrogen-Dependent Obesity and Glucose Intolerance

Wednesday, November 15 | 5:00PM - 6:45PM
Serotonin in Diseases
Room: Summit A

Speaker 3 of 4
Robin L. Haynes, Children's Hospital Boston, USA
High Levels of Serum Serotonin in Sudden Infant Death Syndrome

Wednesday, November 15 | 5:00PM - 6:45PM
Serotonin in Diseases
Room: Summit A

Speaker 4 of 4
Terence Keith Smith, University of Nevada School of Medicine, USA
Does Neuronal Serotonin Have a Role in Colonic Motor Patterns?

Wednesday, November 15 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Summit A


Wednesday, November 15 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Summit B & C
No registration fees are used to fund alcohol served at this function.

Wednesday, November 15 | 8:00PM - 11:00PM
Entertainment
Room: Summit B & C
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Wednesday, November 15 | 8:00PM - 11:00PM
Cash Bar
Room: Summit B & C


Thursday, November 16 | 10:24AM - 10:24AM
Departure


*Session Chair.