Web Desc
Microbiome, Host Resistance and Disease
joint with Manipulation of the Gut Microbiota for Metabolic Health
Organizer(s): Wendy S. Garrett, Yasmine Belkaid and Janelle S. Ayres
Date: March 04 - 08, 2018
Location: Fairmont Banff Springs, Banff, AB, Canada
Sponsored by Merck & Co., Inc.
Summary of Meeting:
The concept that the microbiome shapes health and susceptibility to disease has taken the biomedical sciences by storm. The microbiota is emerging as a fundamental force influencing diverse aspects of physiology reflected in the sessions of this conference. Microbiome studies are at a critical juncture and facing a challenging transition from descriptive studies of association towards mechanistic studies tackling causality. Essential for this transition is a diversity of thinking (chemical and systems biology, metabolism, microbiology, physiology and immunology) and approaches (assays and models). As the basic tools for characterizing microbiomes are now widely accessible, the conference seeks to broaden the base of what defines membership in microbiome studies by inviting investigators to share their vision, approach and results to enhance understanding and mechanistic approaches. In summary, the conference aims to: 1) Introduce a breadth of challenges and biological systems for microbiome studies; 2) Showcase young and senior investigators relevant to advancing next-gen microbiome studies; and 3) Foster collaborative, multidisciplinary microbiome research that advances basic and translational science.
Scholarship Deadline: November 1 2017
Discounted Abstract Deadline: November 1 2017
Abstract Deadline: December 1 2017
Discounted Registration Deadline: January 9 2018
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Merck & Co., Inc.
We gratefully acknowledge additional support from these exhibitors at this conference:
DiversigenMicrobiome Insights, Inc.
We gratefully acknowledge additional support for this conference from:
American Association for Cancer Research (AACR)Kenneth Rainin FoundationSeres Therapeutics
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, March 04 | 4:00PM - 8:00PM
Arrival and Registration
Room: Van Horne Foyer


Sunday, March 04 | 6:00PM - 8:00PM
Welcome Mixer
Room: Van Horne Foyer
No registration fees are used to fund alcohol served at this function.

Monday, March 05 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Monday, March 05 | 8:00AM - 9:00AM
Welcome and Keynote Address (Joint)
Room: Van Horne A/B

Speaker 5 of 5
Andreas J. Bäumler, University of California, Davis, USA
Healthy Guts Exclude Oxygen

Monday, March 05 | 8:00AM - 9:00AM
Welcome and Keynote Address (Joint)
Room: Van Horne A/B

Speaker 4 of 5
* Yasmine Belkaid, NIAID, National Institutes of Health, USA

Monday, March 05 | 8:00AM - 9:00AM
Welcome and Keynote Address (Joint)
Room: Van Horne A/B

Speaker 3 of 5
* Nathalie Delzenne, Université Catholique de Louvain, Belgium

Monday, March 05 | 8:00AM - 9:00AM
Welcome and Keynote Address (Joint)
Room: Van Horne A/B

Speaker 2 of 5
* Liping Zhao, Shanghai Jiao Tong University, China and Rutgers University, USA

Monday, March 05 | 8:00AM - 9:00AM
Welcome and Keynote Address (Joint)
Room: Van Horne A/B

Speaker 1 of 5
* Janelle S. Ayres, The Salk Institute for Biological Studies, USA

Monday, March 05 | 9:00AM - 11:30AM
Microbiota and Cardio-vascular-Metabolic Health (Joint)
Room: Van Horne A/B

Speaker 6 of 6
Amy McMillan, Cleveland Clinic, USA
Short Talk: The Gut Microbe-Dependent Metabolite Trimethylamine N-oxide (TMAO) Is Associated with Multiple Measures of
Periodontal Disease and Cardiovascular Disease Risk


Monday, March 05 | 9:00AM - 11:30AM
Microbiota and Cardio-vascular-Metabolic Health (Joint)
Room: Van Horne A/B

Speaker 5 of 6
Julia H. Kreznar, University of Wisconsin-Madison, USA
Short Talk: Identifying the Genetic Determinants of Gut Microbiome Composition on a Western Diet

Monday, March 05 | 9:00AM - 11:30AM
Microbiota and Cardio-vascular-Metabolic Health (Joint)
Room: Van Horne A/B

Speaker 4 of 6
Liping Zhao, Shanghai Jiao Tong University, China and Rutgers University, USA
Ecological Understanding of the Causative Role of Gut Microbiota in Human Metabolic Health

Monday, March 05 | 9:00AM - 11:30AM
Microbiota and Cardio-vascular-Metabolic Health (Joint)
Room: Van Horne A/B


Coffee Break

Monday, March 05 | 9:00AM - 11:30AM
Microbiota and Cardio-vascular-Metabolic Health (Joint)
Room: Van Horne A/B

Speaker 2 of 6
* Fredrik Bäckhed, University of Gothenburg, Sweden
Mechanistic Studies of the Impact of the Gut Microbiome on Obesity and Type 2 Diabetes

Monday, March 05 | 9:00AM - 11:30AM
Microbiota and Cardio-vascular-Metabolic Health (Joint)
Room: Van Horne A/B

Speaker 1 of 6
* Lora V. Hooper, University of Texas Southwestern Medical Center, USA

Monday, March 05 | 11:30AM - 1:00PM
Poster Setup
Room: Mezzanine 2


Monday, March 05 | 11:30AM - 5:00PM
On Own for Lunch


Monday, March 05 | 1:00PM - 10:00PM
Poster Viewing
Room: Mezzanine 2


Monday, March 05 | 2:30PM - 4:30PM
Workshop: Metagenomic, Metatranscriptomic and Multi'Omic Mic
robiome Analyses (Joint)
Room: Van Horne A/B
This workshop will provide an introduction to study design tools and analysis methods for emerging molecular tools in human microbiome population studies, integrating detailed metagenomic, metatranscriptomic, and other culture-independent molecular methods. Alternating between lecture content and hands-on activities, tutorial presentations will walk attendees through the typical steps in a meta’omic study design and analysis workflow: 1) integration of multiple molecular techniques within a study, 2) bioinformatics for metagenomes and metatranscriptomes, 3) and profiling of microbial community features (taxa, strains, pathways, genes, small molecules, and others). The hands-on components of the tutorial will introduce the bioBakery suite of meta’omic analysis methods, which are publicly available and will be used online through a cloud interface during the workshop. Attendees will work on their personal laptops and interact with their instances through a web browser-based graphical interface (https://bitbucket.org/biobakery/biobakery/wiki/biobakery_workshop).

Tutorial Schedule:

Multi’omics for human microbiome studies (20 minutes, Curtis Huttenhower)

Tutorial setup (15 minutes, Melanie Schirmer)

Metagenome taxonomic and strain profiling (20 minutes, Kevin Bonham)

Lab: StrainPhlAn (25 minutes, Kevin Bonham)

Meta’omic functional profiling (15 minutes, Eric Franzosa)

Lab: HUMAnN2 (25 minutes, Eric Franzosa)
Speaker 1 of 1
* Curtis Huttenhower, Harvard School of Public Health, USA

Monday, March 05 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Monday, March 05 | 5:00PM - 7:15PM
The Gut Microbiome in the Control of Fat Metabolism (Joint)
Room: Van Horne A/B

Speaker 5 of 6
Kelsey E. Huus, University of British Columbia, Canada
Short Talk: The Development of IgA-Lactobacillus Interactions Is Disrupted during Malnutrition and Environmental Enteropathy

Monday, March 05 | 5:00PM - 7:15PM
The Gut Microbiome in the Control of Fat Metabolism (Joint)
Room: Van Horne A/B

Speaker 4 of 6
Patrice D. Cani, Université Catholique de Louvain, Belgium
Intestinal Endocannabinoids, Gut Microbes and Adiposity: Novel Mechanisms

Monday, March 05 | 5:00PM - 7:15PM
The Gut Microbiome in the Control of Fat Metabolism (Joint)
Room: Van Horne A/B

Speaker 3 of 6
Mirko Trajkovski, University of Geneva - CMU, Switzerland
The Microbiota and the Browning of Adipose Tissue

Monday, March 05 | 5:00PM - 7:15PM
The Gut Microbiome in the Control of Fat Metabolism (Joint)
Room: Van Horne A/B

Speaker 2 of 6
* Anna Mae Diehl, Duke University, USA
The Gut Microbiome and NAFLD Pathogenesis

Monday, March 05 | 5:00PM - 7:15PM
The Gut Microbiome in the Control of Fat Metabolism (Joint)
Room: Van Horne A/B

Speaker 1 of 6
* Fredrik Bäckhed, University of Gothenburg, Sweden

Monday, March 05 | 5:00PM - 7:15PM
The Gut Microbiome in the Control of Fat Metabolism (Joint)
Room: Van Horne A/B

Speaker 6 of 6
Philippe Gerard, INRA, France
Short Talk: A Bacterial Species Isolated from an Obese Human Gut Triggers Non-Alcoholic Fatty Liver Disease in Germ-Free Mice through Lps-Dependent Mechanism

Monday, March 05 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Mezzanine 2
No registration fees are used to fund alcohol served at this function.

Monday, March 05 | 7:30PM - 10:00PM
Poster Session 1
Room: Mezzanine 2-Cascade Room


Tuesday, March 06 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Tuesday, March 06 | 8:00AM - 11:15AM
The Microbiota of Early Life and Developmental Immunology
Room: Van Horne A/B

Speaker 1 of 7
Maria G. Dominguez-Bello, Rutgers University, USA
Effect of C-Section on the Microbiota and Host Phenotype

Tuesday, March 06 | 8:00AM - 11:15AM
The Microbiota of Early Life and Developmental Immunology
Room: Van Horne A/B

Speaker 2 of 7
* Andrew J.S. Macpherson, University of Bern, Switzerland
The Maternal Microbiota and Early Postnatal Innate Immune Development

Tuesday, March 06 | 8:00AM - 11:15AM
The Microbiota of Early Life and Developmental Immunology
Room: Van Horne A/B


Coffee Break

Tuesday, March 06 | 8:00AM - 11:15AM
The Microbiota of Early Life and Developmental Immunology
Room: Van Horne A/B

Speaker 4 of 7
Gregory M. Barton, University of California, Berkeley, USA
Determinants of CD4 T Cell Responses to the Microbiota

Tuesday, March 06 | 8:00AM - 11:15AM
The Microbiota of Early Life and Developmental Immunology
Room: Van Horne A/B

Speaker 5 of 7
Michael D. Rosenblum, University of California, San Francisco, USA
Neonatal Regulatory T Cells and Immune Tolerance to Skin Commensals

Tuesday, March 06 | 8:00AM - 11:15AM
The Microbiota of Early Life and Developmental Immunology
Room: Van Horne A/B

Speaker 6 of 7
Brittany Needham, California Institute of Technology, USA
Short Talk: Gut Bacterial Production of a Single Metabolite Causes Behavioral Abnormalities Related to Anxiety and Autism Spectrum Disorder

Tuesday, March 06 | 8:00AM - 11:15AM
The Microbiota of Early Life and Developmental Immunology
Room: Van Horne A/B

Speaker 7 of 7
Michael G. Constantinides, The Scripps Research Institute, USA
Short Talk: Mucosal-Associated Invariant T Cells Respond to Cutaneous Microbiota

Tuesday, March 06 | 8:00AM - 11:15AM
Microbiota and Metabolic Disorders
This session is from Gut Microbiota
Room: Van Horne C

Speaker 1 of 8
* Ruth E. Ley, Max Planck Institute for Developmental Biology, Germany


Tuesday, March 06 | 8:00AM - 11:15AM
Microbiota and Metabolic Disorders
This session is from Gut Microbiota
Room: Van Horne C

Speaker 2 of 8
Emily P. Balskus, Harvard University, USA
Deciphering Gut Microbiota-Drug Interactions with Chemistry


Tuesday, March 06 | 8:00AM - 11:15AM
Microbiota and Metabolic Disorders
This session is from Gut Microbiota
Room: Van Horne C

Speaker 3 of 8
François Leulier, Institut de Génomique Fonctionnelle de Lyon, France
Host-Microbiota Mutualism upon Chronic Undernutrition: Lessons from Gnotobiotic Animal Models


Tuesday, March 06 | 8:00AM - 11:15AM
Microbiota and Metabolic Disorders
This session is from Gut Microbiota
Room: Van Horne C


Coffee Break


Tuesday, March 06 | 8:00AM - 11:15AM
Microbiota and Metabolic Disorders
This session is from Gut Microbiota
Room: Van Horne C

Speaker 5 of 8
Herbert Tilg, Medical University Innsbruck, Austria
Microbiome and Liver Diseases


Tuesday, March 06 | 8:00AM - 11:15AM
Microbiota and Metabolic Disorders
This session is from Gut Microbiota
Room: Van Horne C

Speaker 6 of 8
Eran Elinav, Weizmann Institute of Science, Israel
Host Microbiome Interactions in Health and Disease


Tuesday, March 06 | 8:00AM - 11:15AM
Microbiota and Metabolic Disorders
This session is from Gut Microbiota
Room: Van Horne C

Speaker 7 of 8
Chenhong Zhang, Shanghai Jiao Tong University, China
Short Talk: Predominant Gut Lactobacillus murinus Strain Mediates the Anti-Inflammaging Effects in Calorie-Restricted Mice


Tuesday, March 06 | 8:00AM - 11:15AM
Microbiota and Metabolic Disorders
This session is from Gut Microbiota
Room: Van Horne C

Speaker 8 of 8
Tim Hendrikx, University of California, San Diego, USA
Short Talk: Engineered Lactobacillus reuteri that Secretes IL-22 in the Gut Ameliorates Alcohol-Induced Liver Damage in Mice by Inducing Antimicrobial Molecules Reg3ß and Reg3?


Tuesday, March 06 | 11:15AM - 5:00PM
On Own for Lunch


Tuesday, March 06 | 11:15AM - 1:00PM
Poster Setup
Room: Mezzanine 2


Tuesday, March 06 | 1:00PM - 10:00PM
Poster Viewing
Room: Mezzanine 2


Tuesday, March 06 | 2:30PM - 4:30PM
Workshop and Panel: Discovery, Translation and Commercializa
tion in Microbiome Research and Development: Opportunities and Challenges
Room: Van Horne A/B

Speaker 1 of 4
David N. Cook, Seres Therapeutics, Inc., USA
Treating IBD with Multi-Species Bacterial Consortia

Tuesday, March 06 | 2:30PM - 4:30PM
Workshop and Panel: Discovery, Translation and Commercializa
tion in Microbiome Research and Development: Opportunities and Challenges
Room: Van Horne A/B

Speaker 2 of 4
Henry J. Haiser, Novartis Institutes for BioMedical Research, USA
Facing the Challenges and Opportunities of Microbiome Research—a Big Pharma Perspective

Tuesday, March 06 | 2:30PM - 4:30PM
Workshop and Panel: Discovery, Translation and Commercializa
tion in Microbiome Research and Development: Opportunities and Challenges
Room: Van Horne A/B

Speaker 3 of 4
* Thomas Gajewski, University of Chicago, USA
Prospect of Manipulating the Microbiota as a Cancer Immunotherapeutic

Tuesday, March 06 | 2:30PM - 4:30PM
Workshop and Panel: Discovery, Translation and Commercializa
tion in Microbiome Research and Development: Opportunities and Challenges
Room: Van Horne A/B

Speaker 4 of 4
Maria G. Dominguez-Bello, Rutgers University, USA
Challenges in Translation of Microbiome Research

Tuesday, March 06 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Tuesday, March 06 | 5:00PM - 7:00PM
Mechanistics Microbiome Function in Physiology and Aging
Room: Van Horne A/B

Speaker 1 of 5
* Janelle S. Ayres, The Salk Institute for Biological Studies, USA

Tuesday, March 06 | 5:00PM - 7:00PM
Mechanistics Microbiome Function in Physiology and Aging
Room: Van Horne A/B

Speaker 2 of 5
Meghan A. Koch, Fred Hutchinson Cancer Researc, USA
Maternal Antibodies Regulate Neonatal Health

Tuesday, March 06 | 5:00PM - 7:00PM
Mechanistics Microbiome Function in Physiology and Aging
Room: Van Horne A/B

Speaker 3 of 5
Sarkis K. Mazmanian, California Institute of Technology, USA
Gut Microbiomes from Human Autism Spectrum Disorder Alter Behaviors in Mice

Tuesday, March 06 | 5:00PM - 7:00PM
Mechanistics Microbiome Function in Physiology and Aging
Room: Van Horne A/B

Speaker 4 of 5
Nicholas Bessman, Weill Cornell Medicine, USA
Short Talk: A Dendritic Cell-Derived Hormone Regulates Microbiome Colonization and Repair in the Intestine

Tuesday, March 06 | 5:00PM - 7:00PM
Mechanistics Microbiome Function in Physiology and Aging
Room: Van Horne A/B

Speaker 5 of 5
Rachel R. Caspi, NEI, National Institutes of Health, USA
Short Talk: The Good and The Bad: Two Faces of an Ocular Surface Commensal

Tuesday, March 06 | 5:00PM - 7:00PM
Gut Barrier Alterations and Host Metabolic Disorders
This session is from Gut Microbiota
Room: Van Horne C

Speaker 1 of 5
* Robert W. Karp, National Institutes of Health, USA


Tuesday, March 06 | 5:00PM - 7:00PM
Gut Barrier Alterations and Host Metabolic Disorders
This session is from Gut Microbiota
Room: Van Horne C

Speaker 2 of 5
Lora V. Hooper, University of Texas Southwestern Medical Center, USA
How the Microbiota, the Immune System and the Circadian Clock Interact to Regulate Metabolism


Tuesday, March 06 | 5:00PM - 7:00PM
Gut Barrier Alterations and Host Metabolic Disorders
This session is from Gut Microbiota
Room: Van Horne C

Speaker 3 of 5
Philippe Langella, Institut National de la Recherche Agronomique, France
Microbial Bioactive Metabolites and Gut Function


Tuesday, March 06 | 5:00PM - 7:00PM
Gut Barrier Alterations and Host Metabolic Disorders
This session is from Gut Microbiota
Room: Van Horne C

Speaker 4 of 5
Michiel Kleerebezem, Wageningen University, Netherlands
Small Intestine Microbiota and Host Metabolism


Tuesday, March 06 | 5:00PM - 7:00PM
Gut Barrier Alterations and Host Metabolic Disorders
This session is from Gut Microbiota
Room: Van Horne C

Speaker 5 of 5
Jun Sun, University of Illinois at Chicago, USA
Short Talk: Vitamin D Receptor Regulation of Microbiome in Inflammation and Obesity


Tuesday, March 06 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mezzanine 2
No registration fees are used to fund alcohol served at this function.

Tuesday, March 06 | 7:30PM - 10:00PM
Poster Session 2
Room: Mezzanine 2-Cascade Room


Wednesday, March 07 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Wednesday, March 07 | 8:00AM - 11:15AM
The Microbiota and Resistance to Infectious Diseases
Room: Van Horne A/B

Speaker 1 of 7
* Sara R. Cherry, University of Pennsylvania, USA
Defining the Inter-Kingdom Interactions that Impact Enteric Viral Infections

Wednesday, March 07 | 8:00AM - 11:15AM
The Microbiota and Resistance to Infectious Diseases
Room: Van Horne A/B

Speaker 2 of 7
Howard C. Hang, Rockefeller University, USA
Chemical Dissection of Gut Bacteria Protection Mechanisms

Wednesday, March 07 | 8:00AM - 11:15AM
The Microbiota and Resistance to Infectious Diseases
Room: Van Horne A/B


Coffee Break

Wednesday, March 07 | 8:00AM - 11:15AM
The Microbiota and Resistance to Infectious Diseases
Room: Van Horne A/B

Speaker 4 of 7
Kerwyn Casey Huang, Stanford University, USA
Resilience of the Gut Microbiota to Perturbations

Wednesday, March 07 | 8:00AM - 11:15AM
The Microbiota and Resistance to Infectious Diseases
Room: Van Horne A/B

Speaker 5 of 7
Ken H. Cadwell, New York University School of Medicine, USA
Transkingdom Interactions and Colonization Resistance


Wednesday, March 07 | 8:00AM - 11:15AM
The Microbiota and Resistance to Infectious Diseases
Room: Van Horne A/B

Speaker 6 of 7
Jeffrey R. Singer, University of Alabama at Birmingham, USA
Short Talk: Intestinal Oxygen Regulates Primary Succession and Opportunistic Overgrowth in a Murine Model of Late-Onset Sepsis

Wednesday, March 07 | 8:00AM - 11:15AM
The Microbiota and Resistance to Infectious Diseases
Room: Van Horne A/B

Speaker 7 of 7
Shai Bel, Bar-Ilan University, Israel
Short Talk: Paneth Cells Secrete Lysozyme via Secretory Autophagy during Bacterial Infection of the Intestine

Wednesday, March 07 | 8:00AM - 11:15AM
Feeding the Gut Microbiota for Health
This session is from Gut Microbiota
Room: Van Horne C

Speaker 1 of 8
* Liping Zhao, Shanghai Jiao Tong University, China and Rutgers University, USA


Wednesday, March 07 | 8:00AM - 11:15AM
Feeding the Gut Microbiota for Health
This session is from Gut Microbiota
Room: Van Horne C

Speaker 2 of 8
Jens Walter, APC Microbiome Ireland. University College Cork, Ireland
Modulation of the Human Gut Microbiota with Non-Digestible Carbohydrates – An Ecological Perspective


Wednesday, March 07 | 8:00AM - 11:15AM
Feeding the Gut Microbiota for Health
This session is from Gut Microbiota
Room: Van Horne C

Speaker 3 of 8
Nathalie Delzenne, Université Catholique de Louvain, Belgium
Feeding the Gut Microbiota with Prebiotics: Which Consequence for Host Health?


Wednesday, March 07 | 8:00AM - 11:15AM
Feeding the Gut Microbiota for Health
This session is from Gut Microbiota
Room: Van Horne C


Coffee Break


Wednesday, March 07 | 8:00AM - 11:15AM
Feeding the Gut Microbiota for Health
This session is from Gut Microbiota
Room: Van Horne C

Speaker 5 of 8
André Marette, Laval University Hospital Research Center, Canada
Exploring the Interaction between Dietary Polyphenols and the Gut Microbiota to Alleviate Obesity-Linked Diseases


Wednesday, March 07 | 8:00AM - 11:15AM
Feeding the Gut Microbiota for Health
This session is from Gut Microbiota
Room: Van Horne C

Speaker 6 of 8
Maria Carmen Collado, Institute of Agrochemistry and Food Technology-Spanish National Research Council, Spain
Maternal Microbiome and its Role in Infant Health


Wednesday, March 07 | 8:00AM - 11:15AM
Feeding the Gut Microbiota for Health
This session is from Gut Microbiota
Room: Van Horne C

Speaker 7 of 8
Long H. Nguyen, Massachusetts General Hospital, USA
Short Talk: The Influence of Dietary Patterns and Intake of Sulfur on Sulfate-Reducing Bacteria Abundance and Function


Wednesday, March 07 | 8:00AM - 11:15AM
Feeding the Gut Microbiota for Health
This session is from Gut Microbiota
Room: Van Horne C

Speaker 8 of 8
Jared D. Hoffman, University of Kentucky, USA
Short Talk: Prebiotics for the Gut Microbiota as an Intervention for Alzheimer's Disease Prevention in APOE4 Carriers


Wednesday, March 07 | 11:00AM - 5:00PM
On Own for Lunch


Wednesday, March 07 | 11:00AM - 1:00PM
Poster Setup
Room: Mezzanine 2


Wednesday, March 07 | 1:00PM - 10:00PM
Poster Viewing
Room: Mezzanine 2


Wednesday, March 07 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Wednesday, March 07 | 5:00PM - 7:00PM
Disease Tolerance, Pathology and the Microbiome
Room: Van Horne A/B

Speaker 1 of 4
Yasmine Belkaid, NIAID, National Institutes of Health, USA
Control of Tissue Immunity and Repair by the Microbiota

Wednesday, March 07 | 5:00PM - 7:00PM
Disease Tolerance, Pathology and the Microbiome
Room: Van Horne A/B

Speaker 2 of 4
Janelle S. Ayres, The Salk Institute for Biological Studies, USA
Micronutrient Metabolism Mediates Healthy Host-Pathogen Interactions

Wednesday, March 07 | 5:00PM - 7:00PM
Disease Tolerance, Pathology and the Microbiome
Room: Van Horne A/B

Speaker 3 of 4
* Denise M. Monack, Stanford University, USA
Microbiota Regulation of Salmonella Persistence and Disease Transmission

Wednesday, March 07 | 5:00PM - 7:00PM
Disease Tolerance, Pathology and the Microbiome
Room: Van Horne A/B

Speaker 4 of 4
Zhenrun Jerry Zhang, Rockefeller University, USA
Short Talk: Control of Salmonella Virulence by Microbiota-Derived Short-Chain Fatty Acids

Wednesday, March 07 | 5:00PM - 7:00PM
Xenobiotics-Microbiota Interactions in Metabolic Diseases
This session is from Gut Microbiota
Room: Van Horne C

Speaker 1 of 6
* Nathalie Delzenne, Université Catholique de Louvain, Belgium


Wednesday, March 07 | 5:00PM - 7:00PM
Xenobiotics-Microbiota Interactions in Metabolic Diseases
This session is from Gut Microbiota
Room: Van Horne C

Speaker 2 of 6
Mark R. Charbonneau, Synlogic, USA
A Genetically Engineered E. coli Nissle to Prevent Hyperammonemia in Urea Cycle Disorders (UCDs)


Wednesday, March 07 | 5:00PM - 7:00PM
Xenobiotics-Microbiota Interactions in Metabolic Diseases
This session is from Gut Microbiota
Room: Van Horne C

Speaker 3 of 6
Leah Guthrie, Albert Einstein College of Medicine, USA
Short Talk: Human Microbiome Signatures of Differential Colorectal Cancer Drug Metabolism


Wednesday, March 07 | 5:00PM - 7:00PM
Xenobiotics-Microbiota Interactions in Metabolic Diseases
This session is from Gut Microbiota
Room: Van Horne C

Speaker 4 of 6
Silke S. Heinzmann, Helmholtz Centre Munich, Germany
Short Talk: Endogenous and Host-Microbial Co-Metabolites in Human Biofluids to Investigate Gut Microbiome Functionality


Wednesday, March 07 | 5:00PM - 7:00PM
Xenobiotics-Microbiota Interactions in Metabolic Diseases
This session is from Gut Microbiota
Room: Van Horne C

Speaker 5 of 6
James R. Brown, GlaxoSmithKline, USA
Short Talk: A Chemogenomics Approach for the Discovery of Human Host Receptor Interactions with Endogenous Microbial Metabolites


Wednesday, March 07 | 5:00PM - 7:00PM
Xenobiotics-Microbiota Interactions in Metabolic Diseases
This session is from Gut Microbiota
Room: Van Horne C

Speaker 6 of 6
Leyuan Li, University of Ottawa, Canada
Short Talk: Rapid Assay of Individuals' Microbiome (RapidAIM) for Understanding Drug-Microbiome Interaction and High-Throughput Drug Screening


Wednesday, March 07 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mezzanine 2
No registration fees are used to fund alcohol served at this function.

Wednesday, March 07 | 7:30PM - 10:00PM
Poster Session 3
Room: Mezzanine 2-Cascade Room


Thursday, March 08 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Thursday, March 08 | 8:00AM - 11:15AM
Cancer, Metabolism and the Microbiome
Room: Van Horne A/B

Speaker 1 of 9
Laure Bindels, Université Catholique de Louvain, Belgium
The Gut Microbiota in Cancer Cachexia

Thursday, March 08 | 8:00AM - 11:15AM
Cancer, Metabolism and the Microbiome
Room: Van Horne A/B

Speaker 2 of 9
* Ravid Straussman, Weizmann Institute of Science, Israel
The Tumor Microbiome and its Effect on Chemoresistance

Thursday, March 08 | 8:00AM - 11:15AM
Cancer, Metabolism and the Microbiome
Room: Van Horne A/B


Coffee Break

Thursday, March 08 | 8:00AM - 11:15AM
Cancer, Metabolism and the Microbiome
Room: Van Horne A/B

Speaker 4 of 9
Dimitra Lamprinaki, Quadram Institute Bioscience, UK
Short Talk: Fusobacterium Nucleatum Is Involved in Tumor Progression through Interaction with Lectins Expressed by Myeloid Cells

Thursday, March 08 | 8:00AM - 11:15AM
Cancer, Metabolism and the Microbiome
Room: Van Horne A/B

Speaker 5 of 9
Clarissa Campbell, Memorial Sloan Ketttering Cancer Center, USA
Short Talk: Extrathymically-Generated Regulatory T Cells Shape the Metabolic Function of the Intestinal Microbiota

Thursday, March 08 | 8:00AM - 11:15AM
Cancer, Metabolism and the Microbiome
Room: Van Horne A/B

Speaker 6 of 9
Marc A. Sze, University of Michigan, USA
Short Talk: The Relationship between the Microbiota and Short-Chain Fatty Acid Levels in Individuals with and without Colorectal Lesion

Thursday, March 08 | 8:00AM - 11:15AM
Cancer, Metabolism and the Microbiome
Room: Van Horne A/B

Speaker 7 of 9
Andriy Morgun, Oregon State University, USA
Short Talk: Transkingdom Network Reveals Bacterial Players Associated with Cervical Cancer Gene Expression Program

Thursday, March 08 | 8:00AM - 11:15AM
Cancer, Metabolism and the Microbiome
Room: Van Horne A/B

Speaker 8 of 9
Stephanie A. Cevallos, University of California, Davis, USA
Short Talk: Investigating a Mechanistic Link Between ER Stress and Colorectal Cancer

Thursday, March 08 | 8:00AM - 11:15AM
Cancer, Metabolism and the Microbiome
Room: Van Horne A/B

Speaker 9 of 9
Yan Yan, Harvard University, USA
Short Talk: Metagenomics of the Mucosal and Stool Microbiome in Lynch Syndrome

Thursday, March 08 | 8:00AM - 11:15AM
Dealing with Microbiome Complexity
This session is from Gut Microbiota
Room: Van Horne C

Speaker 1 of 8
* Joël Doré, INRA / MetaGenoPolis, France


Thursday, March 08 | 8:00AM - 11:15AM
Dealing with Microbiome Complexity
This session is from Gut Microbiota
Room: Van Horne C

Speaker 2 of 8
Ruth E. Ley, Max Planck Institute for Developmental Biology, Germany
Sphingolipid Production by Gut Microbes Impacts Host Metabolism


Thursday, March 08 | 8:00AM - 11:15AM
Dealing with Microbiome Complexity
This session is from Gut Microbiota
Room: Van Horne C

Speaker 3 of 8
Natalia Shulzhenko, Oregon State University, USA
Transkingdom Networks Uncovering Host-Microbiota Interactions


Thursday, March 08 | 8:00AM - 11:15AM
Dealing with Microbiome Complexity
This session is from Gut Microbiota
Room: Van Horne C


Coffee Break


Thursday, March 08 | 8:00AM - 11:15AM
Dealing with Microbiome Complexity
This session is from Gut Microbiota
Room: Van Horne C

Speaker 5 of 8
Peter J. Turnbaugh, University of California, San Francisco, USA
Editing the Microbiome for Precision Medicine


Thursday, March 08 | 8:00AM - 11:15AM
Dealing with Microbiome Complexity
This session is from Gut Microbiota
Room: Van Horne C

Speaker 6 of 8
Colin Hill, University College Cork, Ireland
Phage - Drivers of Microbiome Structure


Thursday, March 08 | 8:00AM - 11:15AM
Dealing with Microbiome Complexity
This session is from Gut Microbiota
Room: Van Horne C

Speaker 7 of 8
Abigail J. Johnson, University of Minnesota, USA
Short Talk: Daily Microbiome-Diet Correspondence in Healthy Individuals


Thursday, March 08 | 8:00AM - 11:15AM
Dealing with Microbiome Complexity
This session is from Gut Microbiota
Room: Van Horne C

Speaker 8 of 8
Penny Oh, Nanyang Technlogical University, Singapore
Short Talk: Friends with Benefits: Gram-Positive Bacteria Keeping Hepatic Clock in Sync


Thursday, March 08 | 11:15AM - 5:00PM
On Own for Lunch


Thursday, March 08 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Thursday, March 08 | 5:00PM - 6:45PM
The Microbiota in Cancer Treatment Toxicities and Immune Res
ponse

Room: Van Horne A/B

Speaker 1 of 4
* Matthew R. Redinbo, University of North Carolina at Chapel Hill, USA
Targeted Inhibitors for the Gut Microbiome


Thursday, March 08 | 5:00PM - 6:45PM
The Microbiota in Cancer Treatment Toxicities and Immune Res
ponse

Room: Van Horne A/B

Speaker 2 of 4
Kristen M. Larsen, University of South Carolina, USA
Short Talk: The Role of the Microbiome in Colorectal Cancer Development and Response to 5-Fluoruracil (5-FU) in ApcMin/+ Mice

Thursday, March 08 | 5:00PM - 6:45PM
The Microbiota in Cancer Treatment Toxicities and Immune Res
ponse

Room: Van Horne A/B

Speaker 3 of 4
Thomas Gajewski, University of Chicago, USA
Anti-Tumor Immune Responses and the Commensal Microbiota

Thursday, March 08 | 5:00PM - 6:45PM
The Microbiota in Cancer Treatment Toxicities and Immune Res
ponse

Room: Van Horne A/B

Speaker 4 of 4
Patricia Diaz, University of Connecticut Health Center, USA
Short Talk: Disruption of Oral Homeostasis by Chemotherapeutic Cancer Treatment

Thursday, March 08 | 5:00PM - 6:45PM
Panel: Faculty and Industry Working Together for Innovation
This session is from Gut Microbiota
Room: Van Horne C

Speaker 1 of 4
* Nathalie Delzenne, Université Catholique de Louvain, Belgium


Thursday, March 08 | 5:00PM - 6:45PM
Panel: Faculty and Industry Working Together for Innovation
This session is from Gut Microbiota
Room: Van Horne C

Speaker 2 of 4
Matthew Henn, Seres Therapeutics, USA
Bugs as Drugs


Thursday, March 08 | 5:00PM - 6:45PM
Panel: Faculty and Industry Working Together for Innovation
This session is from Gut Microbiota
Room: Van Horne C

Speaker 3 of 4
Henry J. Haiser, Novartis Institutes for BioMedical Research, USA
Microbiome Research at NIBR—Microbial Metabolites that Modulate Host Functions


Thursday, March 08 | 5:00PM - 6:45PM
Panel: Faculty and Industry Working Together for Innovation
This session is from Gut Microbiota
Room: Van Horne C

Speaker 4 of 4
Joël Doré, INRA / MetaGenoPolis, France
Preserving and Restoring Man-Microbes Symbiosis


Thursday, March 08 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Van Horne A/B


Thursday, March 08 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
This session is from Gut Microbiota
Room: Van Horne C


Thursday, March 08 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mezzanine 2
No registration fees are used to fund alcohol served at this function.

Thursday, March 08 | 8:00PM - 11:00PM
Entertainment
Room: Mezzanine 2
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, March 08 | 8:00PM - 11:00PM
Cash Bar
Room: Mezzanine 2


Friday, March 09 | 10:24AM - 10:24AM
Departure


*Session Chair.