Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
	Hypoxia: Molecules, Mechanisms and Disease (2020A3)
Mitochondria in Aging and Age-Related Disease (2019J2)

Web Desc
Mitochondrial Biology joint with Selective Autophagy Organizer(s): Jodi Nunnari, Anu Suomalainen-Wartiovaara and Koji Okamoto Date: April 22 - 26, 2018 Location: Westin Miyako Kyoto, Kyoto, Japan Sponsored by Astellas Pharma Inc. and Nestlé Institute of Health Sciences Summary of Meeting: Mitochondria perform fundamental diverse functions in eukaryotic cells, including ATP production and ion and phospholipid homeostasis. They also serve as platforms to integrate signaling pathways and cellular processes, such as innate immunity and autophagy. Mitochondrial functions are tightly linked to mitochondrial form, which is established through coordinated machines that control dynamics, positioning, motility and mitochondrial DNA transmission. Contact sites between mitochondrial with diverse organelles have emerged as key and pervasive regulators of mitochondrial form and function. These contact sites, as well as metabolites, fully integrate mitochondria into the cell and organism. It is therefore not surprising that mitochondrial dysfunction has emerged as a key factor in a myriad of diseases, including neurodegenerative and metabolic disorders. This conference will provide a cutting-edge view of how mitochondrial form and function is controlled and how its myriad of functions impinge on health and disease. Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: We gratefully acknowledge the generous grant for this conference provided by: National Cancer Institute (NCI) Grant No. 1R13CA228548-01 Funding for this conference was made possible (in part) by 1R13CA228548-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Mitochondrial Biology

joint with Selective Autophagy

Organizer(s): Jodi Nunnari, Anu Suomalainen-Wartiovaara and Koji Okamoto

Date: April 22 - 26, 2018
Location: Westin Miyako Kyoto, Kyoto, Japan

Sponsored by Astellas Pharma Inc. and Nestlé Institute of Health Sciences

Summary of Meeting:

Mitochondria perform fundamental diverse functions in eukaryotic cells, including ATP production and ion and phospholipid homeostasis. They also serve as platforms to integrate signaling pathways and cellular processes, such as innate immunity and autophagy. Mitochondrial functions are tightly linked to mitochondrial form, which is established through coordinated machines that control dynamics, positioning, motility and mitochondrial DNA transmission. Contact sites between mitochondrial with diverse organelles have emerged as key and pervasive regulators of mitochondrial form and function. These contact sites, as well as metabolites, fully integrate mitochondria into the cell and organism. It is therefore not surprising that mitochondrial dysfunction has emerged as a key factor in a myriad of diseases, including neurodegenerative and metabolic disorders. This conference will provide a cutting-edge view of how mitochondrial form and function is controlled and how its myriad of functions impinge on health and disease.

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge the generous grant for this conference provided by:

National Cancer Institute (NCI)
Grant No. 1R13CA228548-01
Funding for this conference was made possible (in part) by 1R13CA228548-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, April 22 \| 4:00PM - 8:00PM Arrival and Registration Room: Mizuho Foyer
Sunday, April 22 \| 6:00PM - 8:00PM Welcome Mixer Room: Mizuho Foyer No registration fees are used to fund alcohol served at this function.
Monday, April 23 \| 7:30AM - 8:00AM Poster Setup Room: Mizuho
Monday, April 23 \| 8:00AM - 5:00PM Poster Viewing Room: Mizuho
Monday, April 23 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Mizuho Speaker 1 of 5 * Ivan Dikic, Goethe University Medical School, Germany
Monday, April 23 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Mizuho Speaker 2 of 5 * Jodi Nunnari, University of California, Davis, USA
Monday, April 23 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Mizuho Speaker 3 of 5 David M. Sabatini, Whitehead Institute for Biomedical Research, USA mTOR and Lysosomes in Growth Control
Monday, April 23 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Mizuho Speaker 4 of 5 Jennifer A. Lippincott-Schwartz, Howard Hughes Medical Institute - Janelia Farm, USA Autophagy's Role in Mitochondrial Function and Dysfunction
Monday, April 23 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Mizuho Coffee Break
Monday, April 23 \| 10:00AM - 12:15PM Mitochondrial Dynamics Room: Mizuho Speaker 1 of 6 * Aleksandra Trifunovic, University of Cologne, Germany
Monday, April 23 \| 10:00AM - 12:15PM Mitochondrial Dynamics Room: Mizuho Speaker 2 of 6 Orian S. Shirihai, University of California, Los Angeles, USA Lipid Droplet Mitochondria: Mitochondria With Agenda
Monday, April 23 \| 10:00AM - 12:15PM Mitochondrial Dynamics Room: Mizuho Speaker 3 of 6 David C. Chan, California Institute of Technology, USA Mitochondrial Fusion and Fission in Health and Disease
Monday, April 23 \| 10:00AM - 12:15PM Mitochondrial Dynamics Room: Mizuho Speaker 4 of 6 Thomas Langer, CECAD Research Center, Germany Proteolytic Control of Mitochondrial Membrane Homeostasis
Monday, April 23 \| 10:00AM - 12:15PM Mitochondrial Dynamics Room: Mizuho Speaker 5 of 6 Hiromi Sesaki, Johns Hopkins University School of Medicine, USA Short Talk: Human Brain Evolution Driven by Drp1
Monday, April 23 \| 10:00AM - 12:15PM Mitochondrial Dynamics Room: Mizuho Speaker 6 of 6 Naotada Ishihara, Kurume University, Japan Short Talk: Selective Mitochondrial Fusion by Heterotypic Action between OPA1 and Cardiolipin
Monday, April 23 \| 10:00AM - 12:15PM Aggrephagy and Neurodegenerative Disease This session is from Autophagy Room: Yamashiro Speaker 1 of 6 * Masaaki Komatsu, Juntendo University School of Medicine, Japan
Monday, April 23 \| 10:00AM - 12:15PM Aggrephagy and Neurodegenerative Disease This session is from Autophagy Room: Yamashiro Speaker 2 of 6 Ai Yamamoto, Columbia University, USA Selective Autophagy in the CNS
Monday, April 23 \| 10:00AM - 12:15PM Aggrephagy and Neurodegenerative Disease This session is from Autophagy Room: Yamashiro Speaker 3 of 6 Hong Zhang, Chinese Academy of Sciences, China Loss of Collagen Related to the Cuticle Annular Furrow Activates Systemic Autophagy
Monday, April 23 \| 10:00AM - 12:15PM Aggrephagy and Neurodegenerative Disease This session is from Autophagy Room: Yamashiro Speaker 4 of 6 Anne Simonsen, University of Oslo, Norway Regulation of Selective Autophagy
Monday, April 23 \| 10:00AM - 12:15PM Aggrephagy and Neurodegenerative Disease This session is from Autophagy Room: Yamashiro Speaker 5 of 6 Maneka Chitiprolu, University of Ottawa, Canada Short Talk: A Complex of C9ORF72 and p62 Uses Arginine Methylation to Eliminate FUS and Stress Granules by Autophagy
Monday, April 23 \| 10:00AM - 12:15PM Aggrephagy and Neurodegenerative Disease This session is from Autophagy Room: Yamashiro Speaker 6 of 6 Santosh Chauhan, Institute of Life Sciences, India Short Talk: TRIM16 Control Protein Aggregates Turnover by Regulating NRF2-p62 Axis and Autophagy Process
Monday, April 23 \| 12:15PM - 1:45PM Lunch Room: Mizuho
Monday, April 23 \| 12:45PM - 2:45PM Poster Session 1 Room: Mizuho
Monday, April 23 \| 2:45PM - 4:45PM Workshop 1: Dynamics Room: Mizuho Speaker 1 of 9 * Laura L. Lackner, Northwestern University, USA
Monday, April 23 \| 2:45PM - 4:45PM Workshop 1: Dynamics Room: Mizuho Speaker 2 of 9 Suzanne Hoppins, University of Washington, USA Identification of a New Functional Domain in the Mitofusin Proteins
Monday, April 23 \| 2:45PM - 4:45PM Workshop 1: Dynamics Room: Mizuho Speaker 3 of 9 Mickael Cohen, CNRS-UPMC, France Mechanism and Regulation of Homotypic Fusion between Outer Membranes
Monday, April 23 \| 2:45PM - 4:45PM Workshop 1: Dynamics Room: Mizuho Speaker 4 of 9 Alessandra Maresca, IRCCS Istituto Scienze Neurologiche, Italy OPA3 Mutations Highlight a Patho-Mechanism Involving Fission and Autophagy
Monday, April 23 \| 2:45PM - 4:45PM Workshop 1: Dynamics Room: Mizuho Speaker 5 of 9 Cecilia Patitucci, Université de Paris Descartes, France The Role of MTP18 in Mitochondrial Dynamics and Metabolism
Monday, April 23 \| 2:45PM - 4:45PM Workshop 1: Dynamics Room: Mizuho Speaker 6 of 9 Ken Nakamura, University of California, San Francisco, USA A High-Throughput Screen of Real-Time ATP Levels in Individual Cells Reveals Mechanisms of Energy Failure
Monday, April 23 \| 2:45PM - 4:45PM Workshop 1: Dynamics Room: Mizuho Speaker 7 of 9 Juliette Lee, University of Cambridge, UK Basal Mitophagy Is Widespread in Drosophila but Minimally Affected by Loss of Pink1 or Parkin
Monday, April 23 \| 2:45PM - 4:45PM Workshop 1: Dynamics Room: Mizuho Speaker 8 of 9 Thomas Rival, Aix-Marseille Université, France Mitofusin Mutations Commonly Associated with Charcot-Marie-Tooth Neuropathy Have Opposite Effects on Mitochondrial Fusion
Monday, April 23 \| 2:45PM - 4:45PM Workshop 1: Dynamics Room: Mizuho Speaker 9 of 9 Ramona Schuster, Institute for Genetics, University of Cologne, Germany Cdc48 Regulates a Deubiquitylase Cascade Critical for Mitochondrial Fusion
Monday, April 23 \| 3:00PM - 4:30PM Workshop 1 This session is from Autophagy Room: Yamashiro Speaker 1 of 6 * Hong Zhang, Chinese Academy of Sciences, China
Monday, April 23 \| 3:00PM - 4:30PM Workshop 1 This session is from Autophagy Room: Yamashiro Speaker 2 of 6 Christian Behl, University Medical Center of the Johannes Gutenberg University, Germany RAB18 Modulates Autophagosome Formation and is Functionally Compensated by ATG9A
Monday, April 23 \| 3:00PM - 4:30PM Workshop 1 This session is from Autophagy Room: Yamashiro Speaker 3 of 6 Yasin Dagdas, Gregor Mendel Institute, Austria Role of Autophagy in Phenotypic Plasticity Responses in Plants
Monday, April 23 \| 3:00PM - 4:30PM Workshop 1 This session is from Autophagy Room: Yamashiro Speaker 4 of 6 Marie Witt, Max-Delbrück-Center for Molecular Medicine, Germany Structure-Function Studies on FIP200 Reveal Mechanistic Insights into Selective Autophagy
Monday, April 23 \| 3:00PM - 4:30PM Workshop 1 This session is from Autophagy Room: Yamashiro Speaker 5 of 6 Liang Ge, Tsinghua University, China Endomembrane Remodeling in Autophagic Membrane Formation
Monday, April 23 \| 3:00PM - 4:30PM Workshop 1 This session is from Autophagy Room: Yamashiro Speaker 6 of 6 Maho Hamasaki, Osaka University, Japan Chemical Activation of LC3 Conjugation System Uncover the New Insight of LC3 Lipidation Site
Monday, April 23 \| 4:30PM - 5:00PM Coffee Available Room: Mizuho Foyer
Monday, April 23 \| 5:00PM - 7:15PM Mitochondrial Quality Control Room: Mizuho Speaker 1 of 6 * Richard J. Youle, NINDS, National Institutes of Health, USA
Monday, April 23 \| 5:00PM - 7:15PM Mitochondrial Quality Control Room: Mizuho Speaker 2 of 6 Luca Scorrano, University of Padova, Italy Localized Accumulation of Autophagosomes at Axonal Hillocks Depletes Axons from Damaged Mitochondria
Monday, April 23 \| 5:00PM - 7:15PM Mitochondrial Quality Control Room: Mizuho Speaker 3 of 6 Andrew G. Dillin, University of California, Berkeley, USA Mitochondrial Unfolded Protein Responses
Monday, April 23 \| 5:00PM - 7:15PM Mitochondrial Quality Control Room: Mizuho Speaker 4 of 6 Aleksandra Trifunovic, University of Cologne, Germany Quality Control of Mitochondrial Complex I
Monday, April 23 \| 5:00PM - 7:15PM Mitochondrial Quality Control Room: Mizuho Speaker 5 of 6 Adam L. Hughes, University of Utah, USA Short Talk: The Nucleus Is a Common Quality Control Destination for Failed Mitochondrial Import Substrates
Monday, April 23 \| 5:00PM - 7:15PM Mitochondrial Quality Control Room: Mizuho Speaker 6 of 6 Felix Boos, University of Kaiserslautern, Germany Short Talk: Dissolving the Traffic Jam – How Cells Counteract the Blockage of Mitochondrial Protein Entry Gates
Monday, April 23 \| 5:00PM - 7:00PM Autophagy Receptors and Other Machinery in Selective Autopha gy This session is from Autophagy Room: Yamashiro Speaker 1 of 5 * Noboru Mizushima, University of Tokyo, Japan
Monday, April 23 \| 5:00PM - 7:00PM Autophagy Receptors and Other Machinery in Selective Autopha gy This session is from Autophagy Room: Yamashiro Speaker 2 of 5 Sascha Martens, University of Vienna, Austria Templating Autophagosomal Membrane Growth during Selective Autophagy
Monday, April 23 \| 5:00PM - 7:00PM Autophagy Receptors and Other Machinery in Selective Autopha gy This session is from Autophagy Room: Yamashiro Speaker 3 of 5 Patricia Boya, Centro de Investigaciones Biológicas, CSIC, Spain Mitophagy as a Regulator of Metabolism and Cell Differentiation
Monday, April 23 \| 5:00PM - 7:00PM Autophagy Receptors and Other Machinery in Selective Autopha gy This session is from Autophagy Room: Yamashiro Speaker 4 of 5 Christian Behrends, Ludwig Maximilians University München, Germany Autophagosomal Content Profiling as a Tool to Dissect the Contribution of Autophagy to Proteostasis
Monday, April 23 \| 5:00PM - 7:00PM Autophagy Receptors and Other Machinery in Selective Autopha gy This session is from Autophagy Room: Yamashiro Speaker 5 of 5 Michael Lazarou, Monash University, Australia Short Talk: LC3/GABARAPs Drive Ubiquitin-Independent Recruitment of Optineurin and NDP52 to Amplify Mitophagy
Monday, April 23 \| 7:15PM - 7:15PM On Own for Dinner
Tuesday, April 24 \| 8:00AM - 11:15AM Mitophagy (Joint) Room: Mizuho Speaker 1 of 9 * Nikolaus Pfanner, University of Freiburg, Germany
Tuesday, April 24 \| 8:00AM - 11:15AM Mitophagy (Joint) Room: Mizuho Speaker 2 of 9 * Patricia Boya, Centro de Investigaciones Biológicas, CSIC, Spain
Tuesday, April 24 \| 8:00AM - 11:15AM Mitophagy (Joint) Room: Mizuho Speaker 3 of 9 Richard J. Youle, NINDS, National Institutes of Health, USA Pink1-Parkin Pathway
Tuesday, April 24 \| 8:00AM - 11:15AM Mitophagy (Joint) Room: Mizuho Speaker 4 of 9 Ivan Dikic, Goethe University Medical School, Germany Ubiquitin and TBK1 interplay in Selective Autophagy
Tuesday, April 24 \| 8:00AM - 11:15AM Mitophagy (Joint) Room: Mizuho Coffee Break
Tuesday, April 24 \| 8:00AM - 11:15AM Mitophagy (Joint) Room: Mizuho Speaker 6 of 9 Erika L. F. Holzbaur, University of Pennsylvania, USA Dynamics of Autophagy and Mitophagy in Neurons
Tuesday, April 24 \| 8:00AM - 11:15AM Mitophagy (Joint) Room: Mizuho Speaker 7 of 9 Koji Okamoto, Osaka University, Japan Regulation of Mitochondrial Clearance via ER Factors
Tuesday, April 24 \| 8:00AM - 11:15AM Mitophagy (Joint) Room: Mizuho Speaker 8 of 9 Jane E. Craig, St. Jude Children's Research Hospital, USA Short Talk: MEK5/ERK5-Mediated Regulation of Mitophagy
Tuesday, April 24 \| 8:00AM - 11:15AM Mitophagy (Joint) Room: Mizuho Speaker 9 of 9 Thomas McWilliams, University of Helsinki, Finland Short Talk: Resolving Endogenous PINK1-Parkin Activation to in vivo Mitophagy
Tuesday, April 24 \| 11:15AM - 12:15PM Meet the Editors (Joint) Speaker 1 of 13 * Jodi Nunnari, University of California, Davis, USA
Tuesday, April 24 \| 11:15AM - 12:15PM Meet the Editors (Joint) Speaker 2 of 13 * Anne Simonsen, University of Oslo, Norway
Tuesday, April 24 \| 11:15AM - 12:15PM Meet the Editors (Joint) Speaker 3 of 13 Stella M. Hurtley, Science, UK
Tuesday, April 24 \| 11:15AM - 12:15PM Meet the Editors (Joint) Speaker 4 of 13 Tim Spencer, Journal of Cell Biology, USA
Tuesday, April 24 \| 11:15AM - 12:15PM Meet the Editors (Joint) Speaker 5 of 13 Sharon Ahmad, Journal of Cell Science, UK
Tuesday, April 24 \| 11:15AM - 12:15PM Meet the Editors (Joint) Speaker 6 of 13 Robert Kruger, Cell, USA
Tuesday, April 24 \| 11:15AM - 12:15PM Meet the Editors (Joint) Speaker 7 of 13 Christina Kary, Nature Cell Biology, USA
Tuesday, April 24 \| 11:15AM - 12:15PM Meet the Editors (Joint) Speaker 8 of 13 Petra Gross, Journal of Cell Science, UK
Tuesday, April 24 \| 11:15AM - 12:15PM Meet the Editors (Joint) Speaker 9 of 13 Niki Scaplehorn, Nature Communications, UK
Tuesday, April 24 \| 11:15AM - 12:15PM Meet the Editors (Joint) Speaker 10 of 13 Sadaf Shadan, Nature, UK
Tuesday, April 24 \| 11:15AM - 12:15PM Meet the Editors (Joint) Speaker 11 of 13 Srividya Chandramouli, Cell Press, USA
Tuesday, April 24 \| 11:15AM - 12:15PM Meet the Editors (Joint) Speaker 12 of 13 Paulina Jadwiga Strzyz, Nature Reviews Molecular Cell Biology, UK
Tuesday, April 24 \| 11:15AM - 12:15PM Meet the Editors (Joint) Speaker 13 of 13 Elisabetta Argenzio, EMBO Journal, Germany
Tuesday, April 24 \| 11:15AM - 5:00PM On Own for Lunch
Tuesday, April 24 \| 11:15AM - 1:00PM Poster Setup Room: Mizuho
Tuesday, April 24 \| 1:00PM - 10:00PM Poster Viewing Room: Mizuho
Tuesday, April 24 \| 4:30PM - 5:00PM Coffee Available Room: Mizuho Foyer
Tuesday, April 24 \| 5:00PM - 7:15PM Mitochondrial Motility and Distribution Room: Mizuho Speaker 1 of 6 * Luca Scorrano, University of Padova, Italy
Tuesday, April 24 \| 5:00PM - 7:15PM Mitochondrial Motility and Distribution Room: Mizuho Speaker 2 of 6 Thomas L. Schwarz, Children's Hospital Boston and Harvard Medical School, USA Mitochondrial Motility
Tuesday, April 24 \| 5:00PM - 7:15PM Mitochondrial Motility and Distribution Room: Mizuho Speaker 3 of 6 Benoit Kornmann, ETH Zurich, Switzerland Mechanical Force Induces Mitochondrial Fission via the Canonical Fission Machinery
Tuesday, April 24 \| 5:00PM - 7:15PM Mitochondrial Motility and Distribution Room: Mizuho Speaker 4 of 6 Laura L. Lackner, Northwestern University, USA Mitochondrial Anchors: Positioning Mitochondria and More
Tuesday, April 24 \| 5:00PM - 7:15PM Mitochondrial Motility and Distribution Room: Mizuho Speaker 5 of 6 Guillermo López-Doménech, University College London, UK Short Talk: Miro Proteins Coordinate Microtubule and Actin-Dependent Mitochondrial Transport and Distribution
Tuesday, April 24 \| 5:00PM - 7:15PM Mitochondrial Motility and Distribution Room: Mizuho Speaker 6 of 6 Dane M. Wolf, University of California, Los Angeles, USA Short Talk: Milton1 Coordinates Mitochondrial Motility, Form, and Function with Nutrient Status in ß Cells
Tuesday, April 24 \| 5:00PM - 7:00PM Xenophagy and Autophagy in Immunity This session is from Autophagy Room: Yamashiro Speaker 1 of 5 * Eric H. Baehrecke, University of Massachusetts Medical School, USA
Tuesday, April 24 \| 5:00PM - 7:00PM Xenophagy and Autophagy in Immunity This session is from Autophagy Room: Yamashiro Speaker 2 of 5 Vojo Deretic, University of New Mexico Health Sciences Center, USA GALTOR Regulates mTOR and AMPK and Links Metabolic and Quality Control Functions of Autophagy in Endomembrane Damage
Tuesday, April 24 \| 5:00PM - 7:00PM Xenophagy and Autophagy in Immunity This session is from Autophagy Room: Yamashiro Speaker 3 of 5 John Hunter Brumell, Hospital for Sick Children, Canada How ATG Proteins Limit Listeria Spread
Tuesday, April 24 \| 5:00PM - 7:00PM Xenophagy and Autophagy in Immunity This session is from Autophagy Room: Yamashiro Speaker 4 of 5 Laure-Anne Ligeon, University of Zürich – Institute of Experimental Immunology, Switzerland Short Talk: Mechanisms of LC3-Associated Phagocytosis for MHC Class II Presentation
Tuesday, April 24 \| 5:00PM - 7:00PM Xenophagy and Autophagy in Immunity This session is from Autophagy Room: Yamashiro Speaker 5 of 5 Rachel Ulferts, University of Cambridge, UK Short Talk: Influenza A Infection Triggers a Cellular Response that Resembles Autophagy but has a Distinct Molecular Basis
Tuesday, April 24 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Mizuho No registration fees are used to fund alcohol served at this function.
Tuesday, April 24 \| 7:30PM - 10:00PM Poster Session 2 Room: Mizuho
Wednesday, April 25 \| 8:00AM - 11:15AM Metabolism (Joint) Room: Mizuho Speaker 1 of 9 * Jared Rutter, University of Utah, USA
Wednesday, April 25 \| 8:00AM - 11:15AM Metabolism (Joint) Room: Mizuho Speaker 2 of 9 * Marja Jäättelä, Danish Cancer Society Research Center, Denmark
Wednesday, April 25 \| 8:00AM - 11:15AM Metabolism (Joint) Room: Mizuho Speaker 3 of 9 Andrea Ballabio, Telethon Institute of Genetics and Medicine, Italy An mTOR-TFEB Feedback Loop Controls the Response to Starvation and Physical Exercise and Is Deregulated in Cancer
Wednesday, April 25 \| 8:00AM - 11:15AM Metabolism (Joint) Room: Mizuho Speaker 4 of 9 Masaaki Komatsu, Juntendo University School of Medicine, Japan Selective Autophagy Regulates Lipid Metabolism
Wednesday, April 25 \| 8:00AM - 11:15AM Metabolism (Joint) Room: Mizuho Coffee Break
Wednesday, April 25 \| 8:00AM - 11:15AM Metabolism (Joint) Room: Mizuho Speaker 6 of 9 Anu Suomalainen Wartiovaara, University of Helsinki, Finland Metabolic Basis of Mitochondrial Disease
Wednesday, April 25 \| 8:00AM - 11:15AM Metabolism (Joint) Room: Mizuho Speaker 7 of 9 Norbert Perrimon, Harvard Medical School, USA Physiological Regulation of Organismal Homeostasis
Wednesday, April 25 \| 8:00AM - 11:15AM Metabolism (Joint) Room: Mizuho Speaker 8 of 9 Myung-Shik Lee, Yonsei University College of Medicine, South Korea Short Talk: Role of Mitophagy in Pancreatic Beta Cell Function
Wednesday, April 25 \| 8:00AM - 11:15AM Metabolism (Joint) Room: Mizuho Speaker 9 of 9 Martin Graef, Max Planck Institute for Biology of Aging, Germany Short Talk: Autophagy Functions in Mitochondrial DNA Maintenance and Copy Number Regulation
Wednesday, April 25 \| 11:15AM - 5:00PM On Own for Lunch
Wednesday, April 25 \| 11:15AM - 1:00PM Poster Setup Room: Mizuho
Wednesday, April 25 \| 1:00PM - 10:00PM Poster Viewing Room: Mizuho
Wednesday, April 25 \| 2:30PM - 4:30PM Workshop 2: Communication Room: Mizuho Speaker 1 of 9 * Adam L. Hughes, University of Utah, USA
Wednesday, April 25 \| 2:30PM - 4:30PM Workshop 2: Communication Room: Mizuho Speaker 2 of 9 Yusuke Hirabayashi, Columbia University, USA ER-Mitochondria Tethering by PDZD8 Regulates Ca2+ Dynamics in Mammalian Neurons
Wednesday, April 25 \| 2:30PM - 4:30PM Workshop 2: Communication Room: Mizuho Speaker 3 of 9 Yvette C. Wong, Northwestern University, USA Mitochondria-Lysosome Contacts Regulate Mitochondrial Fission via Rab7 GTP Hydrolysis
Wednesday, April 25 \| 2:30PM - 4:30PM Workshop 2: Communication Room: Mizuho Speaker 4 of 9 Thomas Ryan Hurd, New York University School of Medicine, USA Mitochondrial Fragmentation Drives the Selective Removal of Deleterious Mitochondrial DNA in the Drosophila Germline
Wednesday, April 25 \| 2:30PM - 4:30PM Workshop 2: Communication Room: Mizuho Speaker 5 of 9 Lena Pernas, University of Padua, Italy Mitochondria Limit Toxoplasma Growth by Competing for Fatty Acids
Wednesday, April 25 \| 2:30PM - 4:30PM Workshop 2: Communication Room: Mizuho Speaker 6 of 9 Keisuke Takeda, Tokyo University of Pharmacy and Life Sciences, Japan MITOL Prevents ER Stress-Induced Apoptosis via IRE1a Ubiquitylation at ER-Mitochondria Contact Sites
Wednesday, April 25 \| 2:30PM - 4:30PM Workshop 2: Communication Room: Mizuho Speaker 7 of 9 Michal Turek, University of Warsaw, Poland Spatial Relationship between Mitochondria and the Protein Quality Control System
Wednesday, April 25 \| 2:30PM - 4:30PM Workshop 2: Communication Room: Mizuho Speaker 8 of 9 Magali R. VanLinden, University of Bergen, Norway Mitochondrial NAD is a Key Determinant of the Metabolic Profile of Human Cells and is Connected to the Peroxisomal NAD Pool
Wednesday, April 25 \| 2:30PM - 4:30PM Workshop 2: Communication Room: Mizuho Speaker 9 of 9 David A. Stroud, University of Melbourne, Australia Systems Approaches to Understanding the Assembly of Mitochondrial Machines
Wednesday, April 25 \| 4:30PM - 5:00PM Coffee Available Room: Mizuho Foyer
Wednesday, April 25 \| 5:00PM - 7:15PM Mitochondrial Communication I Room: Mizuho Speaker 1 of 6 * Orian S. Shirihai, University of California, Los Angeles, USA
Wednesday, April 25 \| 5:00PM - 7:15PM Mitochondrial Communication I Room: Mizuho Speaker 2 of 6 Gia K. Voeltz, University of Colorado Boulder, USA ER-Linked Mitochondrial Division
Wednesday, April 25 \| 5:00PM - 7:15PM Mitochondrial Communication I Room: Mizuho Speaker 3 of 6 Jared Rutter, University of Utah, USA Novel Mitochondrial Biochemistry
Wednesday, April 25 \| 5:00PM - 7:15PM Mitochondrial Communication I Room: Mizuho Speaker 4 of 6 Peter Walter, HHMI/University of California, San Francisco, USA Signaling in the Unfolded Protein Response
Wednesday, April 25 \| 5:00PM - 7:15PM Mitochondrial Communication I Room: Mizuho Speaker 5 of 6 Peter Rehling, University Medical Centre Göttingen, Germany Short Talk: Defective Mitochondrial Cardiolipin-Remodeling Dampens HIF1-alpha Transcription
Wednesday, April 25 \| 5:00PM - 7:15PM Mitochondrial Communication I Room: Mizuho Speaker 6 of 6 Jakob Daniel Busch, Max-Planck-Institute for Biology of Ageing, Germany Short Talk: MitoRibo-Tag Mice to Study the Mitochondrial Ribosome in vivo
Wednesday, April 25 \| 5:00PM - 7:00PM Organellophagy Other than Mitophagy This session is from Autophagy Room: Yamashiro Speaker 1 of 5 * Vojo Deretic, University of New Mexico Health Sciences Center, USA
Wednesday, April 25 \| 5:00PM - 7:00PM Organellophagy Other than Mitophagy This session is from Autophagy Room: Yamashiro Speaker 2 of 5 Hitoshi Nakatogawa, Tokyo Institute of Technology, Japan Molecular Mechanisms of Organellophagy in Yeast
Wednesday, April 25 \| 5:00PM - 7:00PM Organellophagy Other than Mitophagy This session is from Autophagy Room: Yamashiro Speaker 3 of 5 Eric H. Baehrecke, University of Massachusetts Medical School, USA Novel Regulators of Organelle Autophagy
Wednesday, April 25 \| 5:00PM - 7:00PM Organellophagy Other than Mitophagy This session is from Autophagy Room: Yamashiro Speaker 4 of 5 Tamotsu Yoshimori, Osaka University, Japan Dissection of Molecular Mechanisms in Lysophagy
Wednesday, April 25 \| 5:00PM - 7:00PM Organellophagy Other than Mitophagy This session is from Autophagy Room: Yamashiro Speaker 5 of 5 Heeseon An, Harvard Medical School, USA Short Talk: Systematic Analysis of Ribophagy in Human Cells Reveals Bystander Degradation during Selective Autophagy
Wednesday, April 25 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Mizuho No registration fees are used to fund alcohol served at this function.
Wednesday, April 25 \| 7:30PM - 10:00PM Poster Session 3 Room: Mizuho
Thursday, April 26 \| 7:30AM - 8:00AM Poster Setup Room: Mizuho
Thursday, April 26 \| 8:00AM - 5:00PM Poster Viewing Room: Mizuho
Thursday, April 26 \| 8:00AM - 11:15AM Regulation of Mitochondrial Biogenesis Room: Mizuho Speaker 1 of 8 * Thomas Langer, CECAD Research Center, Germany
Thursday, April 26 \| 8:00AM - 11:15AM Regulation of Mitochondrial Biogenesis Room: Mizuho Speaker 2 of 8 Nikolaus Pfanner, University of Freiburg, Germany Protein Biogenesis and Architecture of Mitochondria
Thursday, April 26 \| 8:00AM - 11:15AM Regulation of Mitochondrial Biogenesis Room: Mizuho Speaker 3 of 8 Elena I. Rugarli, University of Cologne, Germany Post-Transcriptional Control of Mitochondrial Function
Thursday, April 26 \| 8:00AM - 11:15AM Regulation of Mitochondrial Biogenesis Room: Mizuho Coffee Break
Thursday, April 26 \| 8:00AM - 11:15AM Regulation of Mitochondrial Biogenesis Room: Mizuho Speaker 5 of 8 Brendan J. Battersby, University of Helsinki, Finland Selective Mitochondrial Proteotoxicity Triggers a Stress Response on Membrane Dynamics and Ribosomes
Thursday, April 26 \| 8:00AM - 11:15AM Regulation of Mitochondrial Biogenesis Room: Mizuho Speaker 6 of 8 Eric A. Shoubridge, McGill University, Canada Mitochondria 101: Mitochondrial Interaction Network
Thursday, April 26 \| 8:00AM - 11:15AM Regulation of Mitochondrial Biogenesis Room: Mizuho Speaker 7 of 8 Stefan Jakobs, Max Planck Institute for Biophysical Chemistry, Germany Short Talk: Spatial Distribution of Mitochondrial Translation and OXPHOS Complex Assembly
Thursday, April 26 \| 8:00AM - 11:15AM Regulation of Mitochondrial Biogenesis Room: Mizuho Speaker 8 of 8 Sofia Zaganelli, University of Geneva, Switzerland Short Talk: Identification of Mitochondrial RNA Granules Assembly Factors and Regulators using an Image-Based siRNA Screen
Thursday, April 26 \| 8:00AM - 11:15AM Endo-Lysosome System This session is from Autophagy Room: Yamashiro Speaker 1 of 8 * Hitoshi Nakatogawa, Tokyo Institute of Technology, Japan
Thursday, April 26 \| 8:00AM - 11:15AM Endo-Lysosome System This session is from Autophagy Room: Yamashiro Speaker 2 of 8 Noboru Mizushima, University of Tokyo, Japan ATG Genes in Zebrafish and Mice
Thursday, April 26 \| 8:00AM - 11:15AM Endo-Lysosome System This session is from Autophagy Room: Yamashiro Speaker 3 of 8 Marja Jäättelä, Danish Cancer Society Research Center, Denmark Lysosomal STAT3 Regulates Intracellular Proton Equilibrium
Thursday, April 26 \| 8:00AM - 11:15AM Endo-Lysosome System This session is from Autophagy Room: Yamashiro Coffee Break
Thursday, April 26 \| 8:00AM - 11:15AM Endo-Lysosome System This session is from Autophagy Room: Yamashiro Speaker 5 of 8 Enrique J. Garcia, Columbia University, USA Short Talk: ESCRT-Mediated Microlipophagy during Lipid Imbalance
Thursday, April 26 \| 8:00AM - 11:15AM Endo-Lysosome System This session is from Autophagy Room: Yamashiro Speaker 6 of 8 Harald Stenmark, Oslo University Hospital, Norway Lysosome Repair vs Lysophagy
Thursday, April 26 \| 8:00AM - 11:15AM Endo-Lysosome System This session is from Autophagy Room: Yamashiro Speaker 7 of 8 Roberto Zoncu, University of California, Berkeley, USA A Nutrient-Induced Affinity Switch Controls mTORC1 Capture by its Lysosomal Scaffold
Thursday, April 26 \| 8:00AM - 11:15AM Endo-Lysosome System This session is from Autophagy Room: Yamashiro Speaker 8 of 8 Arnold Y. Seo, Janelia Research Campus, USA Short Talk: Macroautophagy Enhanced by Mitochondrial Respiration Remodels Vacuole Liquid-Ordered Membrane Domain to Control Micro-Lipophagy
Thursday, April 26 \| 11:15AM - 12:30PM Lunch Room: Mizuho
Thursday, April 26 \| 12:30PM - 2:30PM Poster Session 4 Room: Mizuho
Thursday, April 26 \| 3:00PM - 4:30PM Workshop 2 This session is from Autophagy Room: Yamashiro Speaker 1 of 6 * Tamotsu Yoshimori, Osaka University, Japan
Thursday, April 26 \| 3:00PM - 4:30PM Workshop 2 This session is from Autophagy Room: Yamashiro Speaker 2 of 6 Michael Joseph Munson, University of Oslo, Norway The Regulation of Mitophagy by Lipid-Binding Proteins
Thursday, April 26 \| 3:00PM - 4:30PM Workshop 2 This session is from Autophagy Room: Yamashiro Speaker 3 of 6 Fumiyo Ikeda, IMBA – Institute of Molecular Biotechnology, Austria The IAP Family Member BRUCE Regulates Autophagosome-Lysosome Fusion
Thursday, April 26 \| 3:00PM - 4:30PM Workshop 2 This session is from Autophagy Room: Yamashiro Speaker 4 of 6 Shigeomi Shimizu, Tokyo Medical and Dental University, Japan Mechanisms and Biological Roles of Golgi-Stress-Induced Mitophagy
Thursday, April 26 \| 3:00PM - 4:30PM Workshop 2 This session is from Autophagy Room: Yamashiro Speaker 5 of 6 Martina B. Wirth, Francis Crick Institute, UK Structural Determinants Mediating Selective Binding of Autophagy Adaptors and Receptors to Mammalian ATG8 Proteins
Thursday, April 26 \| 3:00PM - 4:30PM Workshop 2 This session is from Autophagy Room: Yamashiro Speaker 6 of 6 Elena Marcassa, University of Liverpool, UK Regulation of Basal Mitophagy and Pexophagy by the Mitochondrial Deubiquitylase USP30
Thursday, April 26 \| 4:30PM - 5:00PM Coffee Available Room: Mizuho Foyer
Thursday, April 26 \| 5:00PM - 7:00PM Mitochondrial Communication II Room: Mizuho Speaker 1 of 5 * Benoit Kornmann, ETH Zurich, Switzerland
Thursday, April 26 \| 5:00PM - 7:00PM Mitochondrial Communication II Room: Mizuho Speaker 2 of 5 Toshiya Endo, Kyoto Sangyo University, Japan Mitochondrial Protein and Lipid Trafficking
Thursday, April 26 \| 5:00PM - 7:00PM Mitochondrial Communication II Room: Mizuho Speaker 3 of 5 William A. Prinz, NIDDK, National Institutes of Health, USA Link between Lipid Synthesis and Transport to Mitochondria
Thursday, April 26 \| 5:00PM - 7:00PM Mitochondrial Communication II Room: Mizuho Speaker 4 of 5 Jodi Nunnari, University of California, Davis, USA Mitochondrial Behavior
Thursday, April 26 \| 5:00PM - 7:00PM Mitochondrial Communication II Room: Mizuho Speaker 5 of 5 Christoph Uwe Mårtensson, University of Freiburg, Germany Short Talk: Protein Quality Control at the Main Entry Gate for Precursor Proteins into Mitochondria
Thursday, April 26 \| 5:00PM - 6:45PM Therapeutic Regulation of Autophagy This session is from Autophagy Room: Yamashiro Speaker 1 of 4 * Ai Yamamoto, Columbia University, USA
Thursday, April 26 \| 5:00PM - 6:45PM Therapeutic Regulation of Autophagy This session is from Autophagy Room: Yamashiro Speaker 2 of 4 Jayanta Debnath, University of California, San Francisco, USA NBR1, Selective Autophagy and Metastasis
Thursday, April 26 \| 5:00PM - 6:45PM Therapeutic Regulation of Autophagy This session is from Autophagy Room: Yamashiro Speaker 3 of 4 Beat Nyfeler, Novartis Institutes for BioMedical Research, Switzerland Phenotypic Screening Paradigms for Autophagy Pathway Regulators
Thursday, April 26 \| 5:00PM - 6:45PM Therapeutic Regulation of Autophagy This session is from Autophagy Room: Yamashiro Speaker 4 of 4 Noriyuki Matsuda, Tokyo Metropolitan Institute of Medical Science, Japan Mitochondria Quality Control Elucidated from Parkinson's Disease
Thursday, April 26 \| 6:45PM - 7:00PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) This session is from Autophagy Room: Yamashiro
Thursday, April 26 \| 7:00PM - 7:15PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Room: Mizuho
Thursday, April 26 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Mizuho No registration fees are used to fund alcohol served at this function.
Thursday, April 26 \| 8:00PM - 9:00PM Entertainment Room: Mizuho Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
Thursday, April 26 \| 8:00PM - 9:00PM Cash Bar Room: Mizuho
Friday, April 27 \| 10:24AM - 10:24AM Departure *Session Chair.