Web Desc
Selective Autophagy
joint with Mitochondrial Biology
Organizer(s): Tamotsu Yoshimori, Hong Zhang and Anne Simonsen
Date: April 22 - 26, 2018
Location: Westin Miyako Kyoto, Kyoto, Japan
Sponsored by Nestlé Institute of Health Sciences
Summary of Meeting:
Autophagy is an evolutionarily conserved membrane trafficking process which delivers cargos from the cytoplasm to lysosomes and is critical for cellular homeostasis. Although autophagy has long been perceived as a non-selective pathway, researchers are increasingly realizing that autophagy can be highly selective. It has been shown that protein aggregates and damaged or superfluous organelles such as mitochondria, ER, peroxisomes, endosomes and lysosomes can be degraded by autophagy in a highly selective manner. Selective autophagy has also been shown to play an important role in controlling intracellular pathogens. Since several diseases have been linked to dysfunctional selective autophagy, researchers’ interest in the process is increasing. Altering the autophagy level has become a therapeutic target in various diseases, while the exact mechanisms of selective autophagy for each target remain to be uncovered. The primary goal of this program is to integrate and discuss the latest information about the underlying mechanisms of selective autophagy and its implication in diseases.
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Nestlé Institute of Health Sciences
We gratefully acknowledge additional support for this conference from:
Novus Biologicals
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Novartis Pharma AG
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, April 22 | 4:00PM - 8:00PM
Arrival and Registration
Room: Mizuho Foyer


Sunday, April 22 | 6:00PM - 8:00PM
Welcome Mixer
Room: Mizuho Foyer
No registration fees are used to fund alcohol served at this function.

Monday, April 23 | 7:00AM - 8:00AM
Breakfast
Room: Individual Hotel


Monday, April 23 | 7:30AM - 8:00AM
Poster Setup
Room: Mizuho


Monday, April 23 | 8:00AM - 5:00PM
Poster Viewing
Room: Mizuho


Monday, April 23 | 8:00AM - 9:30AM
Welcome and Keynote Session (Joint)
Room: Mizuho

Speaker 1 of 5
* Ivan Dikic, Goethe University Medical School, Germany

Monday, April 23 | 8:00AM - 9:30AM
Welcome and Keynote Session (Joint)
Room: Mizuho

Speaker 2 of 5
* Jodi Nunnari, University of California, Davis, USA

Monday, April 23 | 8:00AM - 9:30AM
Welcome and Keynote Session (Joint)
Room: Mizuho

Speaker 3 of 5
David M. Sabatini, Whitehead Institute for Biomedical Research, USA
mTOR and Lysosomes in Growth Control

Monday, April 23 | 8:00AM - 9:30AM
Welcome and Keynote Session (Joint)
Room: Mizuho

Speaker 4 of 5
Jennifer A. Lippincott-Schwartz, Howard Hughes Medical Institute - Janelia Farm, USA
Autophagy's Role in Mitochondrial Function and Dysfunction

Monday, April 23 | 8:00AM - 9:30AM
Welcome and Keynote Session (Joint)
Room: Mizuho


Coffee Break

Monday, April 23 | 10:00AM - 12:15PM
Aggrephagy and Neurodegenerative Disease
Room: Yamashiro

Speaker 1 of 6
* Masaaki Komatsu, Juntendo University School of Medicine, Japan

Monday, April 23 | 10:00AM - 12:15PM
Aggrephagy and Neurodegenerative Disease
Room: Yamashiro

Speaker 2 of 6
Ai Yamamoto, Columbia University, USA
Selective Autophagy in the CNS

Monday, April 23 | 10:00AM - 12:15PM
Aggrephagy and Neurodegenerative Disease
Room: Yamashiro

Speaker 3 of 6
Hong Zhang, Chinese Academy of Sciences, China
Loss of Collagen Related to the Cuticle Annular Furrow Activates Systemic Autophagy

Monday, April 23 | 10:00AM - 12:15PM
Aggrephagy and Neurodegenerative Disease
Room: Yamashiro

Speaker 4 of 6
Anne Simonsen, University of Oslo, Norway
Regulation of Selective Autophagy

Monday, April 23 | 10:00AM - 12:15PM
Aggrephagy and Neurodegenerative Disease
Room: Yamashiro

Speaker 5 of 6
Maneka Chitiprolu, University of Ottawa, Canada
Short Talk: A Complex of C9ORF72 and p62 Uses Arginine Methylation to Eliminate FUS and Stress Granules by Autophagy

Monday, April 23 | 10:00AM - 12:15PM
Aggrephagy and Neurodegenerative Disease
Room: Yamashiro

Speaker 6 of 6
Santosh Chauhan, Institute of Life Sciences, India
Short Talk: TRIM16 Control Protein Aggregates Turnover by Regulating NRF2-p62 Axis and Autophagy Process

Monday, April 23 | 10:00AM - 12:15PM
Mitochondrial Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 1 of 6
* Aleksandra Trifunovic, University of Cologne, Germany


Monday, April 23 | 10:00AM - 12:15PM
Mitochondrial Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 2 of 6
Orian S. Shirihai, University of California, Los Angeles, USA
Lipid Droplet Mitochondria: Mitochondria With Agenda


Monday, April 23 | 10:00AM - 12:15PM
Mitochondrial Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 3 of 6
David C. Chan, California Institute of Technology, USA
Mitochondrial Fusion and Fission in Health and Disease


Monday, April 23 | 10:00AM - 12:15PM
Mitochondrial Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 4 of 6
Thomas Langer, CECAD Research Center, Germany
Proteolytic Control of Mitochondrial Membrane Homeostasis


Monday, April 23 | 10:00AM - 12:15PM
Mitochondrial Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 5 of 6
Hiromi Sesaki, Johns Hopkins University School of Medicine, USA
Short Talk: Human Brain Evolution Driven by Drp1


Monday, April 23 | 10:00AM - 12:15PM
Mitochondrial Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 6 of 6
Naotada Ishihara, Kurume University, Japan
Short Talk: Selective Mitochondrial Fusion by Heterotypic Action between OPA1 and Cardiolipin


Monday, April 23 | 12:15PM - 1:45PM
Lunch
Room: Mizuho


Monday, April 23 | 12:45PM - 2:45PM
Poster Session 1
Room: Mizuho


Monday, April 23 | 2:45PM - 4:45PM
Workshop 1: Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 1 of 9
* Laura L. Lackner, Northwestern University, USA


Monday, April 23 | 2:45PM - 4:45PM
Workshop 1: Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 2 of 9
Suzanne Hoppins, University of Washington, USA
Identification of a New Functional Domain in the Mitofusin Proteins


Monday, April 23 | 2:45PM - 4:45PM
Workshop 1: Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 3 of 9
Mickael Cohen, CNRS-UPMC, France
Mechanism and Regulation of Homotypic Fusion between Outer Membranes


Monday, April 23 | 2:45PM - 4:45PM
Workshop 1: Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 4 of 9
Alessandra Maresca, IRCCS Istituto Scienze Neurologiche, Italy
OPA3 Mutations Highlight a Patho-Mechanism Involving Fission and Autophagy


Monday, April 23 | 2:45PM - 4:45PM
Workshop 1: Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 5 of 9
Cecilia Patitucci, Université de Paris Descartes, France
The Role of MTP18 in Mitochondrial Dynamics and Metabolism


Monday, April 23 | 2:45PM - 4:45PM
Workshop 1: Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 6 of 9
Ken Nakamura, University of California, San Francisco, USA
A High-Throughput Screen of Real-Time ATP Levels in Individual Cells Reveals Mechanisms of Energy Failure


Monday, April 23 | 2:45PM - 4:45PM
Workshop 1: Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 7 of 9
Juliette Lee, University of Cambridge, UK
Basal Mitophagy Is Widespread in Drosophila but Minimally Affected by Loss of Pink1 or Parkin


Monday, April 23 | 2:45PM - 4:45PM
Workshop 1: Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 8 of 9
Thomas Rival, Aix-Marseille Université, France
Mitofusin Mutations Commonly Associated with Charcot-Marie-Tooth Neuropathy Have Opposite Effects on Mitochondrial Fusion


Monday, April 23 | 2:45PM - 4:45PM
Workshop 1: Dynamics
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 9 of 9
Ramona Schuster, Institute for Genetics, University of Cologne, Germany
Cdc48 Regulates a Deubiquitylase Cascade Critical for Mitochondrial Fusion


Monday, April 23 | 3:00PM - 4:30PM
Workshop 1
Room: Yamashiro

Speaker 1 of 6
* Hong Zhang, Chinese Academy of Sciences, China

Monday, April 23 | 3:00PM - 4:30PM
Workshop 1
Room: Yamashiro

Speaker 2 of 6
Christian Behl, University Medical Center of the Johannes Gutenberg University, Germany
RAB18 Modulates Autophagosome Formation and is Functionally Compensated by ATG9A

Monday, April 23 | 3:00PM - 4:30PM
Workshop 1
Room: Yamashiro

Speaker 3 of 6
Yasin Dagdas, Gregor Mendel Institute, Austria
Role of Autophagy in Phenotypic Plasticity Responses in Plants

Monday, April 23 | 3:00PM - 4:30PM
Workshop 1
Room: Yamashiro

Speaker 4 of 6
Marie Witt, Max-Delbrück-Center for Molecular Medicine, Germany
Structure-Function Studies on FIP200 Reveal Mechanistic Insights into Selective Autophagy

Monday, April 23 | 3:00PM - 4:30PM
Workshop 1
Room: Yamashiro

Speaker 5 of 6
Liang Ge, Tsinghua University, China
Endomembrane Remodeling in Autophagic Membrane Formation

Monday, April 23 | 3:00PM - 4:30PM
Workshop 1
Room: Yamashiro

Speaker 6 of 6
Maho Hamasaki, Osaka University, Japan
Chemical Activation of LC3 Conjugation System Uncover the New Insight of LC3 Lipidation Site

Monday, April 23 | 4:30PM - 5:00PM
Coffee Available
Room: Yamashiro Foyer


Monday, April 23 | 5:00PM - 7:00PM
Autophagy Receptors and Other Machinery in Selective Autopha
gy

Room: Yamashiro

Speaker 1 of 5
* Noboru Mizushima, University of Tokyo, Japan

Monday, April 23 | 5:00PM - 7:00PM
Autophagy Receptors and Other Machinery in Selective Autopha
gy

Room: Yamashiro

Speaker 2 of 5
Sascha Martens, University of Vienna, Austria
Templating Autophagosomal Membrane Growth during Selective Autophagy

Monday, April 23 | 5:00PM - 7:00PM
Autophagy Receptors and Other Machinery in Selective Autopha
gy

Room: Yamashiro

Speaker 3 of 5
Patricia Boya, Centro de Investigaciones Biológicas, CSIC, Spain
Mitophagy as a Regulator of Metabolism and Cell Differentiation

Monday, April 23 | 5:00PM - 7:00PM
Autophagy Receptors and Other Machinery in Selective Autopha
gy

Room: Yamashiro

Speaker 4 of 5
Christian Behrends, Ludwig Maximilians University München, Germany
Autophagosomal Content Profiling as a Tool to Dissect the Contribution of Autophagy to Proteostasis

Monday, April 23 | 5:00PM - 7:00PM
Autophagy Receptors and Other Machinery in Selective Autopha
gy

Room: Yamashiro

Speaker 5 of 5
Michael Lazarou, Monash University, Australia
Short Talk: LC3/GABARAPs Drive Ubiquitin-Independent Recruitment of Optineurin and NDP52 to Amplify Mitophagy

Monday, April 23 | 5:00PM - 7:15PM
Mitochondrial Quality Control
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 1 of 6
* Richard J. Youle, NINDS, National Institutes of Health, USA


Monday, April 23 | 5:00PM - 7:15PM
Mitochondrial Quality Control
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 2 of 6
Luca Scorrano, University of Padova, Italy
Localized Accumulation of Autophagosomes at Axonal Hillocks Depletes Axons from Damaged Mitochondria


Monday, April 23 | 5:00PM - 7:15PM
Mitochondrial Quality Control
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 3 of 6
Andrew G. Dillin, University of California, Berkeley, USA
Mitochondrial Unfolded Protein Responses


Monday, April 23 | 5:00PM - 7:15PM
Mitochondrial Quality Control
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 4 of 6
Aleksandra Trifunovic, University of Cologne, Germany
Quality Control of Mitochondrial Complex I


Monday, April 23 | 5:00PM - 7:15PM
Mitochondrial Quality Control
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 5 of 6
Adam L. Hughes, University of Utah, USA
Short Talk: The Nucleus Is a Common Quality Control Destination for Failed Mitochondrial Import Substrates


Monday, April 23 | 5:00PM - 7:15PM
Mitochondrial Quality Control
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 6 of 6
Felix Boos, University of Kaiserslautern, Germany
Short Talk: Dissolving the Traffic Jam – How Cells Counteract the Blockage of Mitochondrial Protein Entry Gates


Monday, April 23 | 7:00PM - 7:00PM
On Own for Dinner


Tuesday, April 24 | 7:00AM - 8:00AM
Breakfast
Room: Individual Hotel


Tuesday, April 24 | 8:00AM - 11:15AM
Mitophagy (Joint)
Room: Mizuho

Speaker 1 of 9
* Nikolaus Pfanner, University of Freiburg, Germany

Tuesday, April 24 | 8:00AM - 11:15AM
Mitophagy (Joint)
Room: Mizuho

Speaker 2 of 9
* Patricia Boya, Centro de Investigaciones Biológicas, CSIC, Spain

Tuesday, April 24 | 8:00AM - 11:15AM
Mitophagy (Joint)
Room: Mizuho

Speaker 3 of 9
Richard J. Youle, NINDS, National Institutes of Health, USA
Pink1-Parkin Pathway

Tuesday, April 24 | 8:00AM - 11:15AM
Mitophagy (Joint)
Room: Mizuho

Speaker 4 of 9
Ivan Dikic, Goethe University Medical School, Germany
Ubiquitin and TBK1 interplay in Selective Autophagy

Tuesday, April 24 | 8:00AM - 11:15AM
Mitophagy (Joint)
Room: Mizuho


Coffee Break

Tuesday, April 24 | 8:00AM - 11:15AM
Mitophagy (Joint)
Room: Mizuho

Speaker 6 of 9
Erika L. F. Holzbaur, University of Pennsylvania, USA
Dynamics of Autophagy and Mitophagy in Neurons

Tuesday, April 24 | 8:00AM - 11:15AM
Mitophagy (Joint)
Room: Mizuho

Speaker 7 of 9
Koji Okamoto, Osaka University, Japan
Regulation of Mitochondrial Clearance via ER Factors

Tuesday, April 24 | 8:00AM - 11:15AM
Mitophagy (Joint)
Room: Mizuho

Speaker 8 of 9
Jane E. Craig, St. Jude Children's Research Hospital, USA
Short Talk: MEK5/ERK5-Mediated Regulation of Mitophagy

Tuesday, April 24 | 8:00AM - 11:15AM
Mitophagy (Joint)
Room: Mizuho

Speaker 9 of 9
Thomas McWilliams, University of Helsinki, Finland
Short Talk: Resolving Endogenous PINK1-Parkin Activation to in vivo Mitophagy

Tuesday, April 24 | 11:15AM - 12:15PM
Meet the Editors (Joint)

Speaker 1 of 13
* Jodi Nunnari, University of California, Davis, USA

Tuesday, April 24 | 11:15AM - 12:15PM
Meet the Editors (Joint)

Speaker 2 of 13
* Anne Simonsen, University of Oslo, Norway

Tuesday, April 24 | 11:15AM - 12:15PM
Meet the Editors (Joint)

Speaker 3 of 13
Stella M. Hurtley, Science, UK

Tuesday, April 24 | 11:15AM - 12:15PM
Meet the Editors (Joint)

Speaker 4 of 13
Tim Spencer, Journal of Cell Biology, USA

Tuesday, April 24 | 11:15AM - 12:15PM
Meet the Editors (Joint)

Speaker 5 of 13
Sharon Ahmad, Journal of Cell Science, UK

Tuesday, April 24 | 11:15AM - 12:15PM
Meet the Editors (Joint)

Speaker 6 of 13
Robert Kruger, Cell, USA

Tuesday, April 24 | 11:15AM - 12:15PM
Meet the Editors (Joint)

Speaker 7 of 13
Christina Kary, Nature Cell Biology, USA

Tuesday, April 24 | 11:15AM - 12:15PM
Meet the Editors (Joint)

Speaker 8 of 13
Petra Gross, Journal of Cell Science, UK

Tuesday, April 24 | 11:15AM - 12:15PM
Meet the Editors (Joint)

Speaker 9 of 13
Niki Scaplehorn, Nature Communications, UK

Tuesday, April 24 | 11:15AM - 12:15PM
Meet the Editors (Joint)

Speaker 10 of 13
Sadaf Shadan, Nature, UK

Tuesday, April 24 | 11:15AM - 12:15PM
Meet the Editors (Joint)

Speaker 11 of 13
Srividya Chandramouli, Cell Press, USA

Tuesday, April 24 | 11:15AM - 12:15PM
Meet the Editors (Joint)

Speaker 12 of 13
Paulina Jadwiga Strzyz, Nature Reviews Molecular Cell Biology, UK

Tuesday, April 24 | 11:15AM - 12:15PM
Meet the Editors (Joint)

Speaker 13 of 13
Elisabetta Argenzio, EMBO Journal, Germany

Tuesday, April 24 | 11:15AM - 5:00PM
On Own for Lunch


Tuesday, April 24 | 11:15AM - 1:00PM
Poster Setup
Room: Mizuho


Tuesday, April 24 | 1:00PM - 10:00PM
Poster Viewing
Room: Mizuho


Tuesday, April 24 | 4:30PM - 5:00PM
Coffee Available
Room: Yamashiro Foyer


Tuesday, April 24 | 5:00PM - 7:00PM
Xenophagy and Autophagy in Immunity
Room: Yamashiro

Speaker 1 of 5
* Eric H. Baehrecke, University of Massachusetts Medical School, USA

Tuesday, April 24 | 5:00PM - 7:00PM
Xenophagy and Autophagy in Immunity
Room: Yamashiro

Speaker 2 of 5
Vojo Deretic, University of New Mexico Health Sciences Center, USA
GALTOR Regulates mTOR and AMPK and Links Metabolic and Quality Control Functions of Autophagy in Endomembrane Damage

Tuesday, April 24 | 5:00PM - 7:00PM
Xenophagy and Autophagy in Immunity
Room: Yamashiro

Speaker 3 of 5
John Hunter Brumell, Hospital for Sick Children, Canada
How ATG Proteins Limit Listeria Spread


Tuesday, April 24 | 5:00PM - 7:00PM
Xenophagy and Autophagy in Immunity
Room: Yamashiro

Speaker 4 of 5
Laure-Anne Ligeon, University of Zürich – Institute of Experimental Immunology, Switzerland
Short Talk: Mechanisms of LC3-Associated Phagocytosis for MHC Class II Presentation

Tuesday, April 24 | 5:00PM - 7:00PM
Xenophagy and Autophagy in Immunity
Room: Yamashiro

Speaker 5 of 5
Rachel Ulferts, University of Cambridge, UK
Short Talk: Influenza A Infection Triggers a Cellular Response that Resembles Autophagy but has a Distinct Molecular Basis

Tuesday, April 24 | 5:00PM - 7:15PM
Mitochondrial Motility and Distribution
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 1 of 6
* Luca Scorrano, University of Padova, Italy


Tuesday, April 24 | 5:00PM - 7:15PM
Mitochondrial Motility and Distribution
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 2 of 6
Thomas L. Schwarz, Children's Hospital Boston and Harvard Medical School, USA
Mitochondrial Motility


Tuesday, April 24 | 5:00PM - 7:15PM
Mitochondrial Motility and Distribution
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 3 of 6
Benoit Kornmann, ETH Zurich, Switzerland
Mechanical Force Induces Mitochondrial Fission via the Canonical Fission Machinery


Tuesday, April 24 | 5:00PM - 7:15PM
Mitochondrial Motility and Distribution
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 4 of 6
Laura L. Lackner, Northwestern University, USA
Mitochondrial Anchors: Positioning Mitochondria and More


Tuesday, April 24 | 5:00PM - 7:15PM
Mitochondrial Motility and Distribution
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 5 of 6
Guillermo López-Doménech, University College London, UK
Short Talk: Miro Proteins Coordinate Microtubule and Actin-Dependent Mitochondrial Transport and Distribution


Tuesday, April 24 | 5:00PM - 7:15PM
Mitochondrial Motility and Distribution
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 6 of 6
Dane M. Wolf, University of California, Los Angeles, USA
Short Talk: Milton1 Coordinates Mitochondrial Motility, Form, and Function with Nutrient Status in ß Cells


Tuesday, April 24 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mizuho
No registration fees are used to fund alcohol served at this function.

Tuesday, April 24 | 7:30PM - 10:00PM
Poster Session 2
Room: Mizuho


Wednesday, April 25 | 7:00AM - 8:00AM
Breakfast
Room: Individual Hotel


Wednesday, April 25 | 8:00AM - 11:15AM
Metabolism (Joint)
Room: Mizuho

Speaker 1 of 9
* Jared Rutter, University of Utah, USA

Wednesday, April 25 | 8:00AM - 11:15AM
Metabolism (Joint)
Room: Mizuho

Speaker 2 of 9
* Marja Jäättelä, Danish Cancer Society Research Center, Denmark

Wednesday, April 25 | 8:00AM - 11:15AM
Metabolism (Joint)
Room: Mizuho

Speaker 3 of 9
Andrea Ballabio, Telethon Institute of Genetics and Medicine, Italy
An mTOR-TFEB Feedback Loop Controls the Response to Starvation and Physical Exercise and Is Deregulated in Cancer

Wednesday, April 25 | 8:00AM - 11:15AM
Metabolism (Joint)
Room: Mizuho

Speaker 4 of 9
Masaaki Komatsu, Juntendo University School of Medicine, Japan
Selective Autophagy Regulates Lipid Metabolism

Wednesday, April 25 | 8:00AM - 11:15AM
Metabolism (Joint)
Room: Mizuho


Coffee Break

Wednesday, April 25 | 8:00AM - 11:15AM
Metabolism (Joint)
Room: Mizuho

Speaker 6 of 9
Anu Suomalainen Wartiovaara, University of Helsinki, Finland
Metabolic Basis of Mitochondrial Disease

Wednesday, April 25 | 8:00AM - 11:15AM
Metabolism (Joint)
Room: Mizuho

Speaker 7 of 9
Norbert Perrimon, Harvard Medical School, USA
Physiological Regulation of Organismal Homeostasis

Wednesday, April 25 | 8:00AM - 11:15AM
Metabolism (Joint)
Room: Mizuho

Speaker 8 of 9
Myung-Shik Lee, Yonsei University College of Medicine, South Korea
Short Talk: Role of Mitophagy in Pancreatic Beta Cell Function

Wednesday, April 25 | 8:00AM - 11:15AM
Metabolism (Joint)
Room: Mizuho

Speaker 9 of 9
Martin Graef, Max Planck Institute for Biology of Aging, Germany
Short Talk: Autophagy Functions in Mitochondrial DNA Maintenance and Copy Number Regulation

Wednesday, April 25 | 11:15AM - 5:00PM
On Own for Lunch


Wednesday, April 25 | 11:15AM - 1:00PM
Poster Setup
Room: Mizuho


Wednesday, April 25 | 1:00PM - 10:00PM
Poster Viewing
Room: Mizuho


Wednesday, April 25 | 2:30PM - 4:30PM
Workshop 2: Communication
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 1 of 9
* Adam L. Hughes, University of Utah, USA


Wednesday, April 25 | 2:30PM - 4:30PM
Workshop 2: Communication
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 2 of 9
Yusuke Hirabayashi, Columbia University, USA
ER-Mitochondria Tethering by PDZD8 Regulates Ca2+ Dynamics in Mammalian Neurons


Wednesday, April 25 | 2:30PM - 4:30PM
Workshop 2: Communication
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 3 of 9
Yvette C. Wong, Northwestern University, USA
Mitochondria-Lysosome Contacts Regulate Mitochondrial Fission via Rab7 GTP Hydrolysis


Wednesday, April 25 | 2:30PM - 4:30PM
Workshop 2: Communication
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 4 of 9
Thomas Ryan Hurd, New York University School of Medicine, USA
Mitochondrial Fragmentation Drives the Selective Removal of Deleterious Mitochondrial DNA in the Drosophila Germline


Wednesday, April 25 | 2:30PM - 4:30PM
Workshop 2: Communication
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 5 of 9
Lena Pernas, University of Padua, Italy
Mitochondria Limit Toxoplasma Growth by Competing for Fatty Acids


Wednesday, April 25 | 2:30PM - 4:30PM
Workshop 2: Communication
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 6 of 9
Keisuke Takeda, Tokyo University of Pharmacy and Life Sciences, Japan
MITOL Prevents ER Stress-Induced Apoptosis via IRE1a Ubiquitylation at ER-Mitochondria Contact Sites


Wednesday, April 25 | 2:30PM - 4:30PM
Workshop 2: Communication
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 7 of 9
Michal Turek, University of Warsaw, Poland
Spatial Relationship between Mitochondria and the Protein Quality Control System


Wednesday, April 25 | 2:30PM - 4:30PM
Workshop 2: Communication
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 8 of 9
Magali R. VanLinden, University of Bergen, Norway
Mitochondrial NAD is a Key Determinant of the Metabolic Profile of Human Cells and is Connected to the Peroxisomal NAD Pool


Wednesday, April 25 | 2:30PM - 4:30PM
Workshop 2: Communication
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 9 of 9
David A. Stroud, University of Melbourne, Australia
Systems Approaches to Understanding the Assembly of Mitochondrial Machines


Wednesday, April 25 | 4:30PM - 5:00PM
Coffee Available
Room: Yamashiro Foyer


Wednesday, April 25 | 5:00PM - 7:00PM
Organellophagy Other than Mitophagy
Room: Yamashiro

Speaker 1 of 5
* Vojo Deretic, University of New Mexico Health Sciences Center, USA

Wednesday, April 25 | 5:00PM - 7:00PM
Organellophagy Other than Mitophagy
Room: Yamashiro

Speaker 2 of 5
Hitoshi Nakatogawa, Tokyo Institute of Technology, Japan
Molecular Mechanisms of Organellophagy in Yeast

Wednesday, April 25 | 5:00PM - 7:00PM
Organellophagy Other than Mitophagy
Room: Yamashiro

Speaker 3 of 5
Eric H. Baehrecke, University of Massachusetts Medical School, USA
Novel Regulators of Organelle Autophagy

Wednesday, April 25 | 5:00PM - 7:00PM
Organellophagy Other than Mitophagy
Room: Yamashiro

Speaker 4 of 5
Tamotsu Yoshimori, Osaka University, Japan
Dissection of Molecular Mechanisms in Lysophagy

Wednesday, April 25 | 5:00PM - 7:00PM
Organellophagy Other than Mitophagy
Room: Yamashiro

Speaker 5 of 5
Heeseon An, Harvard Medical School, USA
Short Talk: Systematic Analysis of Ribophagy in Human Cells Reveals Bystander Degradation during Selective Autophagy

Wednesday, April 25 | 5:00PM - 7:15PM
Mitochondrial Communication I
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 1 of 6
* Orian S. Shirihai, University of California, Los Angeles, USA


Wednesday, April 25 | 5:00PM - 7:15PM
Mitochondrial Communication I
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 2 of 6
Gia K. Voeltz, University of Colorado Boulder, USA
ER-Linked Mitochondrial Division


Wednesday, April 25 | 5:00PM - 7:15PM
Mitochondrial Communication I
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 3 of 6
Jared Rutter, University of Utah, USA
Novel Mitochondrial Biochemistry


Wednesday, April 25 | 5:00PM - 7:15PM
Mitochondrial Communication I
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 4 of 6
Peter Walter, HHMI/University of California, San Francisco, USA
Signaling in the Unfolded Protein Response


Wednesday, April 25 | 5:00PM - 7:15PM
Mitochondrial Communication I
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 5 of 6
Peter Rehling, University Medical Centre Göttingen, Germany
Short Talk: Defective Mitochondrial Cardiolipin-Remodeling Dampens HIF1-alpha Transcription


Wednesday, April 25 | 5:00PM - 7:15PM
Mitochondrial Communication I
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 6 of 6
Jakob Daniel Busch, Max-Planck-Institute for Biology of Ageing, Germany
Short Talk: MitoRibo-Tag Mice to Study the Mitochondrial Ribosome in vivo


Wednesday, April 25 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mizuho
No registration fees are used to fund alcohol served at this function.

Wednesday, April 25 | 7:30PM - 10:00PM
Poster Session 3
Room: Mizuho


Thursday, April 26 | 7:00AM - 8:00AM
Breakfast
Room: Individual Hotel


Thursday, April 26 | 7:30AM - 8:00AM
Poster Setup
Room: Mizuho


Thursday, April 26 | 8:00AM - 5:00PM
Poster Viewing
Room: Mizuho


Thursday, April 26 | 8:00AM - 11:15AM
Endo-Lysosome System
Room: Yamashiro

Speaker 1 of 8
* Hitoshi Nakatogawa, Tokyo Institute of Technology, Japan

Thursday, April 26 | 8:00AM - 11:15AM
Endo-Lysosome System
Room: Yamashiro

Speaker 2 of 8
Noboru Mizushima, University of Tokyo, Japan
ATG Genes in Zebrafish and Mice

Thursday, April 26 | 8:00AM - 11:15AM
Endo-Lysosome System
Room: Yamashiro

Speaker 3 of 8
Marja Jäättelä, Danish Cancer Society Research Center, Denmark
Lysosomal STAT3 Regulates Intracellular Proton Equilibrium

Thursday, April 26 | 8:00AM - 11:15AM
Endo-Lysosome System
Room: Yamashiro


Coffee Break

Thursday, April 26 | 8:00AM - 11:15AM
Endo-Lysosome System
Room: Yamashiro

Speaker 5 of 8
Enrique J. Garcia, Columbia University, USA
Short Talk: ESCRT-Mediated Microlipophagy during Lipid Imbalance

Thursday, April 26 | 8:00AM - 11:15AM
Endo-Lysosome System
Room: Yamashiro

Speaker 6 of 8
Harald Stenmark, Oslo University Hospital, Norway
Lysosome Repair vs Lysophagy

Thursday, April 26 | 8:00AM - 11:15AM
Endo-Lysosome System
Room: Yamashiro

Speaker 7 of 8
Roberto Zoncu, University of California, Berkeley, USA
A Nutrient-Induced Affinity Switch Controls mTORC1 Capture by its Lysosomal Scaffold

Thursday, April 26 | 8:00AM - 11:15AM
Endo-Lysosome System
Room: Yamashiro

Speaker 8 of 8
Arnold Y. Seo, Janelia Research Campus, USA
Short Talk: Macroautophagy Enhanced by Mitochondrial Respiration Remodels Vacuole Liquid-Ordered Membrane Domain to Control Micro-Lipophagy

Thursday, April 26 | 8:00AM - 11:15AM
Regulation of Mitochondrial Biogenesis
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 1 of 8
* Thomas Langer, CECAD Research Center, Germany


Thursday, April 26 | 8:00AM - 11:15AM
Regulation of Mitochondrial Biogenesis
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 2 of 8
Nikolaus Pfanner, University of Freiburg, Germany
Protein Biogenesis and Architecture of Mitochondria


Thursday, April 26 | 8:00AM - 11:15AM
Regulation of Mitochondrial Biogenesis
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 3 of 8
Elena I. Rugarli, University of Cologne, Germany
Post-Transcriptional Control of Mitochondrial Function


Thursday, April 26 | 8:00AM - 11:15AM
Regulation of Mitochondrial Biogenesis
This session is from Mitochondrial Biology
Room: Mizuho


Coffee Break


Thursday, April 26 | 8:00AM - 11:15AM
Regulation of Mitochondrial Biogenesis
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 5 of 8
Brendan J. Battersby, University of Helsinki, Finland
Selective Mitochondrial Proteotoxicity Triggers a Stress Response on Membrane Dynamics and Ribosomes


Thursday, April 26 | 8:00AM - 11:15AM
Regulation of Mitochondrial Biogenesis
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 6 of 8
Eric A. Shoubridge, McGill University, Canada
Mitochondria 101: Mitochondrial Interaction Network


Thursday, April 26 | 8:00AM - 11:15AM
Regulation of Mitochondrial Biogenesis
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 7 of 8
Stefan Jakobs, Max Planck Institute for Biophysical Chemistry, Germany
Short Talk: Spatial Distribution of Mitochondrial Translation and OXPHOS Complex Assembly


Thursday, April 26 | 8:00AM - 11:15AM
Regulation of Mitochondrial Biogenesis
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 8 of 8
Sofia Zaganelli, University of Geneva, Switzerland
Short Talk: Identification of Mitochondrial RNA Granules Assembly Factors and Regulators using an Image-Based siRNA Screen


Thursday, April 26 | 11:15AM - 12:30PM
Lunch
Room: Mizuho


Thursday, April 26 | 12:30PM - 2:30PM
Poster Session 4
Room: Mizuho


Thursday, April 26 | 3:00PM - 4:30PM
Workshop 2
Room: Yamashiro

Speaker 1 of 6
* Tamotsu Yoshimori, Osaka University, Japan

Thursday, April 26 | 3:00PM - 4:30PM
Workshop 2
Room: Yamashiro

Speaker 2 of 6
Michael Joseph Munson, University of Oslo, Norway
The Regulation of Mitophagy by Lipid-Binding Proteins

Thursday, April 26 | 3:00PM - 4:30PM
Workshop 2
Room: Yamashiro

Speaker 3 of 6
Fumiyo Ikeda, IMBA – Institute of Molecular Biotechnology, Austria
The IAP Family Member BRUCE Regulates Autophagosome-Lysosome Fusion

Thursday, April 26 | 3:00PM - 4:30PM
Workshop 2
Room: Yamashiro

Speaker 4 of 6
Shigeomi Shimizu, Tokyo Medical and Dental University, Japan
Mechanisms and Biological Roles of Golgi-Stress-Induced Mitophagy

Thursday, April 26 | 3:00PM - 4:30PM
Workshop 2
Room: Yamashiro

Speaker 5 of 6
Martina B. Wirth, Francis Crick Institute, UK
Structural Determinants Mediating Selective Binding of Autophagy Adaptors and Receptors to Mammalian ATG8 Proteins

Thursday, April 26 | 3:00PM - 4:30PM
Workshop 2
Room: Yamashiro

Speaker 6 of 6
Elena Marcassa, University of Liverpool, UK
Regulation of Basal Mitophagy and Pexophagy by the Mitochondrial Deubiquitylase USP30

Thursday, April 26 | 4:30PM - 5:00PM
Coffee Available
Room: Yamashiro Foyer


Thursday, April 26 | 5:00PM - 6:45PM
Therapeutic Regulation of Autophagy
Room: Yamashiro

Speaker 1 of 4
* Ai Yamamoto, Columbia University, USA

Thursday, April 26 | 5:00PM - 6:45PM
Therapeutic Regulation of Autophagy
Room: Yamashiro

Speaker 2 of 4
Jayanta Debnath, University of California, San Francisco, USA
NBR1, Selective Autophagy and Metastasis

Thursday, April 26 | 5:00PM - 6:45PM
Therapeutic Regulation of Autophagy
Room: Yamashiro

Speaker 3 of 4
Beat Nyfeler, Novartis Institutes for BioMedical Research, Switzerland
Phenotypic Screening Paradigms for Autophagy Pathway Regulators

Thursday, April 26 | 5:00PM - 6:45PM
Therapeutic Regulation of Autophagy
Room: Yamashiro

Speaker 4 of 4
Noriyuki Matsuda, Tokyo Metropolitan Institute of Medical Science, Japan
Mitochondria Quality Control Elucidated from Parkinson's Disease

Thursday, April 26 | 5:00PM - 7:00PM
Mitochondrial Communication II
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 1 of 5
* Benoit Kornmann, ETH Zurich, Switzerland


Thursday, April 26 | 5:00PM - 7:00PM
Mitochondrial Communication II
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 2 of 5
Toshiya Endo, Kyoto Sangyo University, Japan
Mitochondrial Protein and Lipid Trafficking


Thursday, April 26 | 5:00PM - 7:00PM
Mitochondrial Communication II
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 3 of 5
William A. Prinz, NIDDK, National Institutes of Health, USA
Link between Lipid Synthesis and Transport to Mitochondria


Thursday, April 26 | 5:00PM - 7:00PM
Mitochondrial Communication II
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 4 of 5
Jodi Nunnari, University of California, Davis, USA
Mitochondrial Behavior


Thursday, April 26 | 5:00PM - 7:00PM
Mitochondrial Communication II
This session is from Mitochondrial Biology
Room: Mizuho

Speaker 5 of 5
Christoph Uwe Mårtensson, University of Freiburg, Germany
Short Talk: Protein Quality Control at the Main Entry Gate for Precursor Proteins into Mitochondria


Thursday, April 26 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Yamashiro


Thursday, April 26 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
This session is from Mitochondrial Biology
Room: Mizuho


Thursday, April 26 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mizuho
No registration fees are used to fund alcohol served at this function.

Thursday, April 26 | 8:00PM - 9:00PM
Entertainment
Room: Mizuho
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, April 26 | 8:00PM - 9:00PM
Cash Bar
Room: Mizuho


Friday, April 27 | 10:24AM - 10:24AM
Departure


*Session Chair.