Web Desc
Tuberculosis: Mechanisms, Pathogenesis and Treatment
Organizer(s): Christina L. Stallings, Veronique Anne Dartois, Stewart T. Cole and David Barros
Date: January 17 - 21, 2019
Location: Fairmont Banff Springs, Banff, AB, Canada
Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation

For important information on the coronavirus, please click here
Summary of Meeting:
The Mycobacterium tuberculosis (TB) research and development landscape has seen many exciting breakthroughs over the past two decades. New diagnostics have emerged, innovative research has significantly reduced biological uncertainties and two novel drugs have been launched. In addition, public-private partnerships have been formed, which have dedicated massive efforts aimed at dramatically shortening TB therapy, tackling resistant disease, and developing new vaccines. However, shifts in funding priorities and a false sense of success could threaten the current focus and momentum, which would have catastrophic consequences, making the timing of this conference of paramount importance. This conference seeks to: 1) Reignite collaborative and multidisciplinary research by bringing together experts in basic science, translational research, and drug discovery and development; 2) Bring together young brilliant minds and established investigators to encourage new discussions and the exchange of innovative ideas for strategies moving forward; and 3) Foster cross-fertilization at the interface between research and development, all aspects of which are critical if we are to tackle the TB pandemic and achieve the next innovative leap.
Global Health Travel Award Deadline: August 14 2018
Scholarship Deadline: October 11 2018
Discounted Abstract Deadline: October 11 2018
Abstract Deadline: October 23 2018
Discounted Registration Deadline: November 20 2018
Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.


Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Bill & Melinda Gates Foundation
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Merck & Co., Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1 R13 AI140635-01
Funding for this conference was made possible (in part) by 1 R13 AI140635-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Thursday, January 17 | 4:00PM - 8:00PM
Arrival and Registration
Room: Van Horne Foyer


Thursday, January 17 | 6:00PM - 8:00PM
Welcome Mixer
Room: Van Horne Foyer
No registration fees are used to fund alcohol served at this function.

Friday, January 18 | 7:00AM - 8:00AM
Breakfast
Room: Van Horne B/C


Friday, January 18 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Van Horne A

Speaker 1 of 5
* Christina L. Stallings, Washington University School of Medicine, USA

Friday, January 18 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Van Horne A

Speaker 2 of 5
* Veronique Anne Dartois, Hackensack Meridian Health, USA

Friday, January 18 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Van Horne A

Speaker 3 of 5
* Stewart T. Cole, Institut Pasteur, France

Friday, January 18 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Van Horne A

Speaker 4 of 5
* David Barros, GlaxoSmithKline, Spain

Friday, January 18 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Van Horne A

Speaker 5 of 5
Willem A. Hanekom, Bill & Melinda Gates Foundation, USA
2018: The Year of TB Vaccines!

Friday, January 18 | 9:00AM - 11:45AM
Pathogenic Strategies of Mycobacteria
Room: Van Horne A

Speaker 1 of 8
* Patricia A. Champion, University of Notre Dame, USA

Friday, January 18 | 9:00AM - 11:45AM
Pathogenic Strategies of Mycobacteria
Room: Van Horne A

Speaker 2 of 8
Scarlet S. Shell, Worcester Polytechnic Institute, USA
The Intersection of Stress Response and RNA Metabolism in Mycobacteria


Friday, January 18 | 9:00AM - 11:45AM
Pathogenic Strategies of Mycobacteria
Room: Van Horne A


Coffee Break

Friday, January 18 | 9:00AM - 11:45AM
Pathogenic Strategies of Mycobacteria
Room: Van Horne A

Speaker 4 of 8
Marcel A. Behr, McGill University, Canada
The Revised Time-Table of Tuberculosis and its Implications for Immunopathogenesis

Friday, January 18 | 9:00AM - 11:45AM
Pathogenic Strategies of Mycobacteria
Room: Van Horne A

Speaker 5 of 8
Jeremy Rock, Rockefeller University, USA
Towards CRISPR-Based Functional Genomics in Mtb

Friday, January 18 | 9:00AM - 11:45AM
Pathogenic Strategies of Mycobacteria
Room: Van Horne A

Speaker 6 of 8
Samuel H. Becker, New York University School of Medicine, USA
Short Talk: The Mycobacterium Tuberculosis Proteasome Regulates Nitrate Metabolism through an Essential Protein Quality
Control System


Friday, January 18 | 9:00AM - 11:45AM
Pathogenic Strategies of Mycobacteria
Room: Van Horne A

Speaker 7 of 8
Miriam Braunstein, University of North Carolina at Chapel Hill, USA
Short Talk: Mycobacterium tuberculosis SatS Is a Chaperone for the SecA2 Protein Export Pathway

Friday, January 18 | 9:00AM - 11:45AM
Pathogenic Strategies of Mycobacteria
Room: Van Horne A

Speaker 8 of 8
Damian C. Ekiert, New York University School of Medicine, USA
Short Talk: MCE Protein Architectures Suggest Mechanisms of Transport Across the Envelope

Friday, January 18 | 11:45AM - 5:00PM
On Own for Lunch


Friday, January 18 | 11:45AM - 1:00PM
Poster Setup
Room: Van Horne B/C


Friday, January 18 | 1:00PM - 10:00PM
Poster Viewing
Room: Van Horne B/C


Friday, January 18 | 2:30PM - 4:30PM
Workshop 1: Tuberculosis Comorbidities and Non-Tuberculosis
Mycobacteria
Room: Van Horne A

Speaker 1 of 9
* Blanca I. Restrepo, University of Texas HSC Houston, Brownsville Campus, USA

Friday, January 18 | 2:30PM - 4:30PM
Workshop 1: Tuberculosis Comorbidities and Non-Tuberculosis
Mycobacteria
Room: Van Horne A

Speaker 2 of 9
Tucker J. Piergallini, Texas Biomedical Research Institute, USA
Systemically-Increased Inflammation Causes Enhanced Early Control of Mycobacterium tuberculosis Infection in
Young Mice via an Early Hyper-Inflammatory Immune Response, Mimicking M.tb Infection in Aged Mice


Friday, January 18 | 2:30PM - 4:30PM
Workshop 1: Tuberculosis Comorbidities and Non-Tuberculosis
Mycobacteria
Room: Van Horne A

Speaker 3 of 9
Anna Kathleen Coussens, Walter and Eliza Hall Institute, Australia
Seasonal Immunity in HIV-TB Pathogenesis

Friday, January 18 | 2:30PM - 4:30PM
Workshop 1: Tuberculosis Comorbidities and Non-Tuberculosis
Mycobacteria
Room: Van Horne A

Speaker 4 of 9
Brendan K. Podell, Colorado State University, USA
Early Immune Events Dictating Outcome in Diabetes-Tuberculosis Comorbidity

Friday, January 18 | 2:30PM - 4:30PM
Workshop 1: Tuberculosis Comorbidities and Non-Tuberculosis
Mycobacteria
Room: Van Horne A

Speaker 5 of 9
Ananya Nandy, CSIR-Institute of Genomics and Integrative Biology, India
Feasting on Fat: Lessons Learnt from Adipocyte Model of Mtb Infection

Friday, January 18 | 2:30PM - 4:30PM
Workshop 1: Tuberculosis Comorbidities and Non-Tuberculosis
Mycobacteria
Room: Van Horne A

Speaker 6 of 9
Julia Marianna Scordo, Texas Biomedical Research Institute, USA
Human Alveolar Lining Fluid Drives Mycobacterium tuberculosis Infection Outcome in Alveolar Epithelial Cells

Friday, January 18 | 2:30PM - 4:30PM
Workshop 1: Tuberculosis Comorbidities and Non-Tuberculosis
Mycobacteria
Room: Van Horne A

Speaker 7 of 9
Jaryd Sullivan, McGill University Health Centre, Canada
A Novel Screening Platform for Non-Tuberculous Mycobacteria Drug Discovery

Friday, January 18 | 2:30PM - 4:30PM
Workshop 1: Tuberculosis Comorbidities and Non-Tuberculosis
Mycobacteria
Room: Van Horne A

Speaker 8 of 9
Daniel Barkan, Hebrew University, Israel
The Virulence-Essential Secretion System ESX-4 in Mycobacterium abscessus Is Regulated by a Small Non-Coding RNA

Friday, January 18 | 2:30PM - 4:30PM
Workshop 1: Tuberculosis Comorbidities and Non-Tuberculosis
Mycobacteria
Room: Van Horne A

Speaker 9 of 9
Lawrence Lubyayi, University of the Witwatersrand, Uganda
Immune Sensitization and Evolution of Immune Responses Following BCG at Birth, in Infants of Mothers with and without Latent Mycobacterium tuberculosis Infection

Friday, January 18 | 4:30PM - 5:00PM
Coffee Available


Friday, January 18 | 5:00PM - 7:00PM
Immune Responses to Mycobacterium tuberculosis
Room: Van Horne A

Speaker 1 of 6
* Anca Dorhoi, Friedrich-Loeffler-Institut, Germany

Friday, January 18 | 5:00PM - 7:00PM
Immune Responses to Mycobacterium tuberculosis
Room: Van Horne A

Speaker 2 of 6
Christina L. Stallings, Washington University School of Medicine, USA
Innate Immune Responses to Mycobacterium tuberculosis

Friday, January 18 | 5:00PM - 7:00PM
Immune Responses to Mycobacterium tuberculosis
Room: Van Horne A

Speaker 3 of 6
Katrin D. Mayer-Barber, NIAID, National Institutes of Health, USA
Cellular Dynamics of Innate Effector Cells during Mtb Infection

Friday, January 18 | 5:00PM - 7:00PM
Immune Responses to Mycobacterium tuberculosis
Room: Van Horne A

Speaker 4 of 6
Galit Alter, MIT and Harvard University, USA
Humoral Biomarkers of Mtb Control

Friday, January 18 | 5:00PM - 7:00PM
Immune Responses to Mycobacterium tuberculosis
Room: Van Horne A

Speaker 5 of 6
Jason D. Simmons, University of Washington, USA
Short Talk: Resistance to Latent Mycobacterium tuberculosis Infection Is Associated with Distinct Monocyte Transcriptional Programs

Friday, January 18 | 5:00PM - 7:00PM
Immune Responses to Mycobacterium tuberculosis
Room: Van Horne A

Speaker 6 of 6
Micah Dunlap, Washington University School of Medicine, USA
Short Talk: A Novel Role for C-C Motif Chemokine Receptor 2 during Infection with Hypervirulent Mycobacterium tuberculosis

Friday, January 18 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Van Horne B/C
No registration fees are used to fund alcohol served at this function.

Friday, January 18 | 7:30PM - 10:00PM
Poster Session 1
Room: Van Horne B/C


Saturday, January 19 | 7:00AM - 8:00AM
Breakfast
Room: Van Horne B/C


Saturday, January 19 | 8:00AM - 11:15AM
Host Cell Signaling and Invasion
Room: Van Horne A

Speaker 1 of 9
* Anna D. Tischler, University of Minnesota, USA

Saturday, January 19 | 8:00AM - 11:15AM
Host Cell Signaling and Invasion
Room: Van Horne A

Speaker 2 of 9
Jeffery S. Cox, University of California, Berkeley, USA
Using Global Proteomics to Discover New Anti-TB Pathways of Macrophages

Saturday, January 19 | 8:00AM - 11:15AM
Host Cell Signaling and Invasion
Room: Van Horne A

Speaker 3 of 9
Ulrich E. Schaible, Research Center Borstel, Germany
Pathogen-Host Cell Interactions in Tuberculosis

Saturday, January 19 | 8:00AM - 11:15AM
Host Cell Signaling and Invasion
Room: Van Horne A


Coffee Break

Saturday, January 19 | 8:00AM - 11:15AM
Host Cell Signaling and Invasion
Room: Van Horne A

Speaker 5 of 9
Jyothi Rengarajan, Emory University School of Medicine, USA
Modulation of Innate-Adaptive Crosstalk in Tuberculosis

Saturday, January 19 | 8:00AM - 11:15AM
Host Cell Signaling and Invasion
Room: Van Horne A

Speaker 6 of 9
Michael Shiloh, University of Texas Southwestern Medical Center, USA
Airway Neuron Activation by Mycobacterium tuberculosis

Saturday, January 19 | 8:00AM - 11:15AM
Host Cell Signaling and Invasion
Room: Van Horne A

Speaker 7 of 9
Francisco J. Roca Soler, University of Cambridge, UK
Short Talk: TNF Induces Pathogenic Programmed Macrophage Necrosis in Tuberculosis through a Mitochondrial-Lysosomal-Endoplasmic Reticulum Circuit

Saturday, January 19 | 8:00AM - 11:15AM
Host Cell Signaling and Invasion
Room: Van Horne A

Speaker 8 of 9
Amy K. Barczak, Massachusetts General Hospital, USA
Short Talk: ER Stress and Innate Immune Recognition of Mtb Infection

Saturday, January 19 | 8:00AM - 11:15AM
Host Cell Signaling and Invasion
Room: Van Horne A

Speaker 9 of 9
Julius H. Brandenburg, Research Center Borstel, Germany
Short Talk: Mycobacterium tuberculosis Exploits WNT6-Induced Acetyl-CoA Carboxylase-2-Driven Perturbation of Host Lipid
Homeostasis to Promote Growth in Macrophages


Saturday, January 19 | 11:15AM - 5:00PM
On Own for Lunch


Saturday, January 19 | 11:15AM - 1:00PM
Poster Setup
Room: Van Horne B/C


Saturday, January 19 | 1:00PM - 10:00PM
Poster Viewing
Room: Van Horne B/C


Saturday, January 19 | 2:30PM - 4:30PM
Workshop 2: TB Drug Targets and MOA
Room: Van Horne A

Speaker 1 of 8
* Kyle H. Rohde, University of Central Florida, USA

Saturday, January 19 | 2:30PM - 4:30PM
Workshop 2: TB Drug Targets and MOA
Room: Van Horne A

Speaker 2 of 8
Jyothi Padiadpu, Center for Global Infectious Disease Research, SCRI, USA
Kinome Deconvolution to Delineate Host Regulators and Inhibitors of Tuberculosis Infection

Saturday, January 19 | 2:30PM - 4:30PM
Workshop 2: TB Drug Targets and MOA
Room: Van Horne A

Speaker 3 of 8
Gareth Adrian Prosser, National Institutes of Health, USA
Unraveling the Physiological Roles of the M. tuberculosis PrrAB Two-Component System

Saturday, January 19 | 2:30PM - 4:30PM
Workshop 2: TB Drug Targets and MOA
Room: Van Horne A

Speaker 4 of 8
Valdir C. Barth, Rutgers University, USA
Selective Toxin-Mediated Ribosome Stalling Surgically Reprograms the Mycobacterium tuberculosis Proteome

Saturday, January 19 | 2:30PM - 4:30PM
Workshop 2: TB Drug Targets and MOA
Room: Van Horne A

Speaker 5 of 8
Eachan Oliver Johnson, Broad Institute, USA
Large-Scale Chemical-Genetic Interaction Profiling Yields New Classes of Inhibitors of Mycobacterium tuberculosis

Saturday, January 19 | 2:30PM - 4:30PM
Workshop 2: TB Drug Targets and MOA
Room: Van Horne A

Speaker 6 of 8
Kaley M. Wilburn, Cornell University, USA
Inducing cAMP Production in Mycobacterium tuberculosis Is Sufficient to Stall Cholesterol Utilization

Saturday, January 19 | 2:30PM - 4:30PM
Workshop 2: TB Drug Targets and MOA
Room: Van Horne A

Speaker 7 of 8
Anil Kumar Ojha, Wadsworth Center, University at Albany, USA
Zincxing Mycobacterial Ribosomes: Targeting Regulation of Ribosome Hibernation to Increase Antibiotic Efficacies

Saturday, January 19 | 2:30PM - 4:30PM
Workshop 2: TB Drug Targets and MOA
Room: Van Horne A

Speaker 8 of 8
Fredrik Almqvist, Umeå University, Sweden
Design, Synthesis and Evaluation of Novel ?2- Thiazolino 2-Pyridone Derivatives as Mycobacterium Tuberculosis Tolerance Inhibitors

Saturday, January 19 | 4:30PM - 5:00PM
Coffee Available


Saturday, January 19 | 5:00PM - 7:00PM
Translation of New Therapeutic, Diagnostic and Vaccination S
trategies

Room: Van Horne A

Speaker 1 of 6
* Gerhard Walzl, Stellenbosch University, South Africa

Saturday, January 19 | 5:00PM - 7:00PM
Translation of New Therapeutic, Diagnostic and Vaccination S
trategies

Room: Van Horne A

Speaker 2 of 6
Ranjan Kumar Nanda, International Center for Genetic Engineering and Biotechnology, India
Brain-Gut-Microbiota Axis in Tuberculosis

Saturday, January 19 | 5:00PM - 7:00PM
Translation of New Therapeutic, Diagnostic and Vaccination S
trategies

Room: Van Horne A

Speaker 3 of 6
Jennifer Gardiner, Bill & Melinda Gates Foundation, USA
Biomarkers of Infection, Disease and Response to Therapy

Saturday, January 19 | 5:00PM - 7:00PM
Translation of New Therapeutic, Diagnostic and Vaccination S
trategies

Room: Van Horne A

Speaker 4 of 6
Nicholas Paton, National University of Singapore, Singapore
New Approaches to Testing TB Regimens in Clinical Trials

Saturday, January 19 | 5:00PM - 7:00PM
Translation of New Therapeutic, Diagnostic and Vaccination S
trategies

Room: Van Horne A

Speaker 5 of 6
Phillip A. Swanson II, National Institutes of Health, USA
Short Talk: T Cell Immunity in the Blood following Aerosol, Intravenous or Intradermal Administration of BCG in Nonhuman Primates

Saturday, January 19 | 5:00PM - 7:00PM
Translation of New Therapeutic, Diagnostic and Vaccination S
trategies

Room: Van Horne A

Speaker 6 of 6
Brian D. Robertson, Imperial College London, UK
Short Talk: Development of a Human Challenge Model for Tuberculosis

Saturday, January 19 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Van Horne B/C
No registration fees are used to fund alcohol served at this function.

Saturday, January 19 | 7:30PM - 10:00PM
Poster Session 2
Room: Van Horne B/C


Sunday, January 20 | 7:00AM - 8:00AM
Breakfast
Room: Van Horne B/C


Sunday, January 20 | 8:00AM - 11:15AM
Treatment and Diagnosis of Disease
Room: Van Horne A

Speaker 1 of 9
* Thomas Ioerger, Texas A&M University, USA

Sunday, January 20 | 8:00AM - 11:15AM
Treatment and Diagnosis of Disease
Room: Van Horne A

Speaker 2 of 9
David B. Olsen, Merck and Co., USA
Intracellular Prodrug Activation Yield Selective Oxazolidinone Mycobacterium tuberculosis Inhibitors

Sunday, January 20 | 8:00AM - 11:15AM
Treatment and Diagnosis of Disease
Room: Van Horne A

Speaker 3 of 9
Claudia Denkinger, Foundation for Innovative New Diagnostics, Switzerland
TB Diagnostics

Sunday, January 20 | 8:00AM - 11:15AM
Treatment and Diagnosis of Disease
Room: Van Horne A


Coffee Break

Sunday, January 20 | 8:00AM - 11:15AM
Treatment and Diagnosis of Disease
Room: Van Horne A

Speaker 5 of 9
Rada Savic, University of California, San Francisco, USA
The Right Treatment for the Right Patient: Stratified Medicine in TB

Sunday, January 20 | 8:00AM - 11:15AM
Treatment and Diagnosis of Disease
Room: Van Horne A

Speaker 6 of 9
Anthony David Baughn, University of Minnesota, USA
Conditional Susceptibility to Pyrazinamide Is Driven by a Specific Stress Response in Mycobacterium tuberculosis

Sunday, January 20 | 8:00AM - 11:15AM
Treatment and Diagnosis of Disease
Room: Van Horne A

Speaker 7 of 9
Jan Rybniker, University Clinic Cologne, Germany
Short Talk: Corticosteroids Potently Abrogate p38 MAPK-Dependent Necrotic Cell Death Induced by Mycobacterium tuberculosis – Implications for Host-Directed Therapies

Sunday, January 20 | 8:00AM - 11:15AM
Treatment and Diagnosis of Disease
Room: Van Horne A

Speaker 8 of 9
Janice J. Endsley, University of Texas Medical Branch, USA
Short Talk: Role of Arginine Metabolism Disruption in the Pathogenesis of TB and HIV Co-Infection

Sunday, January 20 | 8:00AM - 11:15AM
Treatment and Diagnosis of Disease
Room: Van Horne A

Speaker 9 of 9
Catherine Ong, National University of Singapore, Singapore
Short Talk: MMP Inhibition Using Doxycycline with Standard Anti-Tuberculous Treatment in TB Patients: A Phase II Randomized-Controlled Trial

Sunday, January 20 | 11:15AM - 5:00PM
On Own for Lunch


Sunday, January 20 | 11:15AM - 1:00PM
Poster Setup
Room: Van Horne B/C


Sunday, January 20 | 1:00PM - 10:00PM
Poster Viewing
Room: Van Horne B/C


Sunday, January 20 | 4:30PM - 5:00PM
Coffee Available


Sunday, January 20 | 5:00PM - 7:00PM
Molecular Dissection and Targeting of Mycobacterium tubercul
osis

Room: Van Horne A

Speaker 1 of 6
* Bree B. Aldridge, Tufts University, USA

Sunday, January 20 | 5:00PM - 7:00PM
Molecular Dissection and Targeting of Mycobacterium tubercul
osis

Room: Van Horne A

Speaker 2 of 6
Robert B. Abramovitch, Michigan State University, USA
Targeting Two-Component Regulatory Systems to Inhibit Mycobacterium tuberculosis Pathogenesis

Sunday, January 20 | 5:00PM - 7:00PM
Molecular Dissection and Targeting of Mycobacterium tubercul
osis

Room: Van Horne A

Speaker 3 of 6
Digby F. Warner, University of Cape Town, South Africa
Catching Bacilli in Flight: Direct Sampling and Analysis of TB Aerosols

Sunday, January 20 | 5:00PM - 7:00PM
Molecular Dissection and Targeting of Mycobacterium tubercul
osis

Room: Van Horne A

Speaker 4 of 6
Stewart T. Cole, Institut Pasteur, France
Innovative Interventions and Imaging

Sunday, January 20 | 5:00PM - 7:00PM
Molecular Dissection and Targeting of Mycobacterium tubercul
osis

Room: Van Horne A

Speaker 5 of 6
Julia Puffal, Rutgers University, USA
Short Talk: Functional Compartmentalization of Plasma Membrane in Mycobacterium tuberculosis

Sunday, January 20 | 5:00PM - 7:00PM
Molecular Dissection and Targeting of Mycobacterium tubercul
osis

Room: Van Horne A

Speaker 6 of 6
Chiara Toniolo, Swiss Federal Institute of Technology in Lausanne, Switzerland
Short Talk: Cell-to-Cell Phenotypic Heterogeneity in the Interactions between Macrophages and Mycobacterium tuberculosis

Sunday, January 20 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Van Horne B/C
No registration fees are used to fund alcohol served at this function.

Sunday, January 20 | 7:30PM - 10:00PM
Poster Session 3
Room: Van Horne B/C


Monday, January 21 | 7:00AM - 8:00AM
Breakfast
Room: Van Horne B/C


Monday, January 21 | 8:00AM - 11:15AM
Mycobacterial and Host Vulnerabilities
Room: Van Horne A

Speaker 1 of 9
* G. Marcela Rodriguez, University of Medicine and Dentistry of New Jersey, USA

Monday, January 21 | 8:00AM - 11:15AM
Mycobacterial and Host Vulnerabilities
Room: Van Horne A

Speaker 2 of 9
David Barros, GlaxoSmithKline, Spain
Drug Discovery and Development in TB

Monday, January 21 | 8:00AM - 11:15AM
Mycobacterial and Host Vulnerabilities
Room: Van Horne A

Speaker 3 of 9
Thomas Dick, Hackensack Meridian Health, USA
Mechanism of Action of PZA

Monday, January 21 | 8:00AM - 11:15AM
Mycobacterial and Host Vulnerabilities
Room: Van Horne A


Coffee Break

Monday, January 21 | 8:00AM - 11:15AM
Mycobacterial and Host Vulnerabilities
Room: Van Horne A

Speaker 5 of 9
Mary Jackson, Colorado State University, USA
Therapeutic Potential of the FAS-II Dehydratases of Mycobacterium tuberculosis

Monday, January 21 | 8:00AM - 11:15AM
Mycobacterial and Host Vulnerabilities
Room: Van Horne A

Speaker 6 of 9
Adrie J. C. Steyn, Africa Health Research Institute & UAB, South Africa
The Human Tuberculous Lung: An Untapped Resource to Generate a High-Resolution 3D Lung Atlas

Monday, January 21 | 8:00AM - 11:15AM
Mycobacterial and Host Vulnerabilities
Room: Van Horne A

Speaker 7 of 9
Andrej Trauner, Swiss Tropical and Public Health Institute, Switzerland
Short Talk: Resource Misallocation as A Mediator of Fitness Costs in Rifampicin Resistance

Monday, January 21 | 8:00AM - 11:15AM
Mycobacterial and Host Vulnerabilities
Room: Van Horne A

Speaker 8 of 9
Rujapak Sutiwisesak, University of Massachusetts Medical School, USA
Short Talk: Natural Polymorphisms in the esxH Gene of Mycobacterium tuberculosis Affect T Cell Immunity Following Infection

Monday, January 21 | 8:00AM - 11:15AM
Mycobacterial and Host Vulnerabilities
Room: Van Horne A

Speaker 9 of 9
Daisy Xiaoxi Ji, University of California, Berkeley, USA
Short Talk: Genetic Control of the Susceptibility to M. tuberculosis Infection by the Sst1S Locus

Monday, January 21 | 11:15AM - 5:00PM
On Own for Lunch


Monday, January 21 | 2:00PM - 3:30PM
Careers in Science
Room: Van Horne A

Speaker 1 of 7
* Christina L. Stallings, Washington University School of Medicine, USA

Monday, January 21 | 2:00PM - 3:30PM
Careers in Science
Room: Van Horne A

Speaker 2 of 7
Jeremy Rock, Rockefeller University, USA

Monday, January 21 | 2:00PM - 3:30PM
Careers in Science
Room: Van Horne A

Speaker 3 of 7
Patricia A. Champion, University of Notre Dame, USA

Monday, January 21 | 2:00PM - 3:30PM
Careers in Science
Room: Van Horne A

Speaker 4 of 7
Elnaz Menhaji-Klotz, Bill & Melinda Gates Medical Research Institute, USA

Monday, January 21 | 2:00PM - 3:30PM
Careers in Science
Room: Van Horne A

Speaker 5 of 7
David Barros, GlaxoSmithKline, Spain

Monday, January 21 | 2:00PM - 3:30PM
Careers in Science
Room: Van Horne A

Speaker 6 of 7
David B. Olsen, Merck and Co., USA

Monday, January 21 | 2:00PM - 3:30PM
Careers in Science
Room: Van Horne A

Speaker 7 of 7
Karen Lacourciere, NIAID, National Institutes of Health, USA

Monday, January 21 | 3:30PM - 4:30PM
Interactive Interviewing Skills

Speaker 1 of 1
* David B. Olsen, Merck and Co., USA

Monday, January 21 | 4:30PM - 5:00PM
Coffee Available


Monday, January 21 | 5:00PM - 6:45PM
Host Determinants of Disease Outcomes
Room: Van Horne A

Speaker 1 of 5
* David M. Tobin, Duke University School of Medicine, USA

Monday, January 21 | 5:00PM - 6:45PM
Host Determinants of Disease Outcomes
Room: Van Horne A

Speaker 2 of 5
Michael Stephen Glickman, Memorial Sloan-Kettering Institute, USA
Microbiome and Tuberculosis

Monday, January 21 | 5:00PM - 6:45PM
Host Determinants of Disease Outcomes
Room: Van Horne A

Speaker 3 of 5
Philana Ling Lin, University of Pittsburgh, USA
Nonhuman Primate Models of TB

Monday, January 21 | 5:00PM - 6:45PM
Host Determinants of Disease Outcomes
Room: Van Horne A

Speaker 4 of 5
Christopher M. Sassetti, University of Massachusetts Medical School, USA
Host and Bacterial Determinants of TB Outcome

Monday, January 21 | 5:00PM - 6:45PM
Host Determinants of Disease Outcomes
Room: Van Horne A

Speaker 5 of 5
Ben Gern, Seattle Children's Research Institute, USA
Short Talk: TGFß Restricts T Cell IFN? Production in Pulmonary Tuberculous Granulomas

Monday, January 21 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Van Horne A


Monday, January 21 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Alberta/New Brunswick
No registration fees are used to fund alcohol served at this function.

Monday, January 21 | 8:00PM - 11:00PM
Entertainment
Room: Alberta/New Brunswick
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Monday, January 21 | 8:00PM - 11:00PM
Cash Bar
Room: Alberta/New Brunswick


Tuesday, January 22 | 10:24AM - 10:24AM
Departure


*Session Chair
†Invited, not yet responded.