Web Desc
Autophagy: From Model Systems to Therapeutic Opportunities
Organizer(s): Vojo Deretic, Li Yu and Leon O. Murphy
Date: February 17 - 21, 2019
Location: Eldorado Hotel & Spa, Santa Fe, NM, USA
This activity is supported by an educational grant from Celgene Corporation
Summary of Meeting:
Autophagy is a homeostatic process strategically positioned at the intersection of metabolism and intracellular quality control, with broad physiological and medical manifestations ranging from metabolic imbalance to neurodegeneration, infections, immune disorders, cancer and aging. In yeast, the formation and organization of the autophagosomal apparatus follows a highly prescribed sequence, starting with the pre-autophagosomal structure and ending in autophagosomal fusion with the yeast vacuole. However, in other model organisms, as well as in mammals, the autophagy machinery and its regulators show both similarities and notable differences relative to yeast. The goals/aims of the conference are: 1) Compare and contrast autophagy in yeast and higher organisms with a focus on both the shared regulators and on those factors that have no counterparts in yeast. 2) Cover the intersection of autophagy with energy metabolism, innate immune signaling and endomembrane damage. 3) Cover how signaling cascades regulate the process of selective autophagy whereby substrates are recruited to forming autophagosomes by receptors and molecular tags such as ubiquitin, galectins, or through other modalities. The conference will cover fundamental principles as outlined above and how they apply to basic and translational aspects of human disease. Intersections with several other stress response processes will be addressed.
Scholarship Deadline: October 23 2018
Discounted Abstract Deadline: October 23 2018
Abstract Deadline: November 15 2018
Discounted Registration Deadline: December 13 2018
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
This activity was supported by an educational grant from Celgene Corporation
We gratefully acknowledge additional support for this conference from:
Bio-TechneGeneTex, Inc.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Denali Therapeutics Inc.

Novartis Institutes for BioMedical Research
We gratefully acknowledge the generous grant for this conference provided by:

National Cancer Institute (NCI)
Grant No. 1 R13 CA232432-01
Funding for this conference was made possible (in part) by 1 R13 CA232432-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, February 17 | 4:00PM - 8:00PM
Arrival and Registration
Room: Cava Santa Fe


Sunday, February 17 | 6:00PM - 8:00PM
Welcome Mixer
Room: Cava Santa Fe
No registration fees are used to fund alcohol served at this function.

Monday, February 18 | 7:00AM - 8:00AM
Breakfast
Room: Cava Santa Fe


Monday, February 18 | 7:30AM - 8:00AM
Poster Setup
Room: Cava Santa Fe


Monday, February 18 | 8:00AM - 7:00PM
Poster Viewing
Room: Cava Santa Fe


Monday, February 18 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Eldorado Grand Ballroom

Speaker 1 of 2
* Vojo Deretic, University of New Mexico Health Sciences Center, USA

Monday, February 18 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Eldorado Grand Ballroom

Speaker 2 of 2
Beth Levine, University of Texas Southwestern Medical Center, USA
Autophagy – A View from Mammalian and Metazoan Studies

Monday, February 18 | 9:00AM - 11:15AM
Autophagy Fundamentals
Room: Eldorado Grand Ballroom

Speaker 1 of 7
* Anne Simonsen, University of Oslo, Norway

Monday, February 18 | 9:00AM - 11:15AM
Autophagy Fundamentals
Room: Eldorado Grand Ballroom

Speaker 2 of 7
* Patrice Codogno, INSERM, France

Monday, February 18 | 9:00AM - 11:15AM
Autophagy Fundamentals
Room: Eldorado Grand Ballroom

Speaker 3 of 7
Ana Maria Cuervo, Albert Einstein College of Medicine, USA
Different Forms of Selective Autophagy

Monday, February 18 | 9:00AM - 11:15AM
Autophagy Fundamentals
Room: Eldorado Grand Ballroom


Coffee Break

Monday, February 18 | 9:00AM - 11:15AM
Autophagy Fundamentals
Room: Eldorado Grand Ballroom

Speaker 5 of 7
Terje Johansen, Institute of Medical Biology, Norway
Selective Autophagy Mediated by Both Sequestosome 1/p62-Like Receptors and Mitophagy Receptors

Monday, February 18 | 9:00AM - 11:15AM
Autophagy Fundamentals
Room: Eldorado Grand Ballroom

Speaker 6 of 7
Chiara De Leonibus, Telethon Institute of Genetics and Medicine, Italy
Short Talk: A Selective ER-Phagy Exerts Procollagen Quality Control via a CALNEXIN-FAM134B Complex

Monday, February 18 | 9:00AM - 11:15AM
Autophagy Fundamentals
Room: Eldorado Grand Ballroom

Speaker 7 of 7
J. Wade Harper, Harvard Medical School, USA
Exploring Proteome Homeostasis Mechanisms using Quantitative Proteomics

Monday, February 18 | 11:15AM - 12:15PM
Lunch
Room: Cava Santa Fe


Monday, February 18 | 12:00PM - 2:30PM
Poster Session 1
Room: Cava Santa Fe


Monday, February 18 | 2:30PM - 4:30PM
Workshop 1: Structural Biology and Proteomics and Autophagy
Room: Eldorado Grand Ballroom

Speaker 1 of 5
* Christian Behrends, Ludwig Maximilians University München, Germany
Proteomics Studies of Autophagy Systems

Monday, February 18 | 2:30PM - 4:30PM
Workshop 1: Structural Biology and Proteomics and Autophagy
Room: Eldorado Grand Ballroom

Speaker 2 of 5
Sharan Swarup, Harvard Medical School, USA
Profiling the Lysophagy Pathway through Quantitative Proteomics

Monday, February 18 | 2:30PM - 4:30PM
Workshop 1: Structural Biology and Proteomics and Autophagy
Room: Eldorado Grand Ballroom

Speaker 3 of 5
* James H. Hurley, University of California, Berkeley, USA
Structural Studies of Autophagy Systems

Monday, February 18 | 2:30PM - 4:30PM
Workshop 1: Structural Biology and Proteomics and Autophagy
Room: Eldorado Grand Ballroom

Speaker 4 of 5
Takanori Otomo, The Scripps Research Institute, USA
Insights into Phagophore Expansion from Structural and Biochemical Analyses of the ATG2A-WIPI4 Complex

Monday, February 18 | 2:30PM - 4:30PM
Workshop 1: Structural Biology and Proteomics and Autophagy
Room: Eldorado Grand Ballroom

Speaker 5 of 5
Carsten Sachse, Forschungszentrum Jülich, Germany
Structural Basis and in situ Visualization of p62/SQSTM1 Polymers by Electron Microscopy

Monday, February 18 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Monday, February 18 | 5:00PM - 7:00PM
mTOR, AMPK, TFEB - Relationship to Autophagy and Other Pathw
ays

Room: Eldorado Grand Ballroom

Speaker 1 of 5
* Patricia Boya, Centro de Investigaciones Biológicas, CSIC, Spain

Monday, February 18 | 5:00PM - 7:00PM
mTOR, AMPK, TFEB - Relationship to Autophagy and Other Pathw
ays

Room: Eldorado Grand Ballroom

Speaker 2 of 5
Roberto Zoncu, University of California, Berkeley, USA
Molecular Mechanisms of Lysosomal mTORC1 Regulation by Cellular Lipids

Monday, February 18 | 5:00PM - 7:00PM
mTOR, AMPK, TFEB - Relationship to Autophagy and Other Pathw
ays

Room: Eldorado Grand Ballroom

Speaker 3 of 5
Wei Liu, Zhejiang University, China
Signal Regulation of Autophagy Initiation

Monday, February 18 | 5:00PM - 7:00PM
mTOR, AMPK, TFEB - Relationship to Autophagy and Other Pathw
ays

Room: Eldorado Grand Ballroom

Speaker 4 of 5
Nuno Raimundo, University Medical Center Goettingen, Germany
Short Talk: Mitochondrial Malfunction Impairs Lysosomal Hydrolysis via AMPK-PtdIns(3,5)P2

Monday, February 18 | 5:00PM - 7:00PM
mTOR, AMPK, TFEB - Relationship to Autophagy and Other Pathw
ays

Room: Eldorado Grand Ballroom

Speaker 5 of 5
Reuben J. Shaw, The Salk Institute for Biological Studies, USA
AMPK and ULK1: Two Critical Kinases in Autophagy Initiation

Monday, February 18 | 7:00PM - 7:00PM
On Own for Dinner


Tuesday, February 19 | 7:00AM - 8:00AM
Breakfast
Room: Cava Santa Fe


Tuesday, February 19 | 8:00AM - 11:00AM
Membrane Trafficking and its Role in Autophagy
Room: Eldorado Grand Ballroom

Speaker 1 of 8
* Fulvio Reggiori, University Medical Centre Groningen, Netherlands

Tuesday, February 19 | 8:00AM - 11:00AM
Membrane Trafficking and its Role in Autophagy
Room: Eldorado Grand Ballroom

Speaker 2 of 8
Ivan Dikic, Goethe University Medical School, Germany
Multiplex CRISPR/Cas Library Screens Targeting Autophagy Networks

Tuesday, February 19 | 8:00AM - 11:00AM
Membrane Trafficking and its Role in Autophagy
Room: Eldorado Grand Ballroom

Speaker 3 of 8
Jin-Mi Heo, Harvard Medical School, USA
Short Talk: RAB7A Phosphorylation by TBK1 Promotes Mitophagy via the PINK-Parkin Pathway

Tuesday, February 19 | 8:00AM - 11:00AM
Membrane Trafficking and its Role in Autophagy
Room: Eldorado Grand Ballroom

Speaker 4 of 8
Noboru Mizushima, University of Tokyo, Japan
Evolution of the ATG12 Conjugation System

Tuesday, February 19 | 8:00AM - 11:00AM
Membrane Trafficking and its Role in Autophagy
Room: Eldorado Grand Ballroom


Coffee Break

Tuesday, February 19 | 8:00AM - 11:00AM
Membrane Trafficking and its Role in Autophagy
Room: Eldorado Grand Ballroom

Speaker 6 of 8
Cheng-Wei Hsieh, Institute of Biological Chemistry, Taiwan
Short Talk: Omegasome-Proximal PtdIns(4,5)P2 Couples F-Actin Mediated Mitoaggregate Disassembly with Autophagosome
Formation during Mitophagy


Tuesday, February 19 | 8:00AM - 11:00AM
Membrane Trafficking and its Role in Autophagy
Room: Eldorado Grand Ballroom

Speaker 7 of 8
Felix Randow, Medical Research Council, UK
Autophagy in Cell-Autonomous Immunity

Tuesday, February 19 | 8:00AM - 11:00AM
Membrane Trafficking and its Role in Autophagy
Room: Eldorado Grand Ballroom

Speaker 8 of 8
Li Yu, Tsinghua University, China
p62 Phase Separation in Autophagy

Tuesday, February 19 | 11:00AM - 5:00PM
On Own for Lunch


Tuesday, February 19 | 11:00AM - 1:00PM
Poster Setup
Room: Cava Santa Fe


Tuesday, February 19 | 1:00PM - 10:00PM
Poster Viewing
Room: Cava Santa Fe


Tuesday, February 19 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Tuesday, February 19 | 5:00PM - 7:00PM
Autophagy Regulation and Processes
Room: Eldorado Grand Ballroom

Speaker 1 of 7
* Maria Ines Vaccaro, University of Buenos Aires, Argentina

Tuesday, February 19 | 5:00PM - 7:00PM
Autophagy Regulation and Processes
Room: Eldorado Grand Ballroom

Speaker 2 of 7
* Qing Zhong, Shanghai Jiao Tong University School of Medicine, China

Tuesday, February 19 | 5:00PM - 7:00PM
Autophagy Regulation and Processes
Room: Eldorado Grand Ballroom

Speaker 3 of 7
Sharon A. Tooze, Francis Crick Institute, UK
Initiation of Autophagosome Formation

Tuesday, February 19 | 5:00PM - 7:00PM
Autophagy Regulation and Processes
Room: Eldorado Grand Ballroom

Speaker 4 of 7
Elizabeth A. Allen, University of Massachusetts Medical School, USA
Short Talk: A Myotubularin-Related Phosphatase that Regulates Autophagic Flux

Tuesday, February 19 | 5:00PM - 7:00PM
Autophagy Regulation and Processes
Room: Eldorado Grand Ballroom

Speaker 5 of 7
David C. Rubinsztein, Cambridge Institute for Medical Research, UK
Depletion of Acetyl-Coenzyme A by Starvation Inhibits mTORC1 Pathway via EP300

Tuesday, February 19 | 5:00PM - 7:00PM
Autophagy Regulation and Processes
Room: Eldorado Grand Ballroom

Speaker 6 of 7
Qiming Sun, Zhejiang University, China
Short Talk: FAM134B Oligomerization Drives ER Membrane Scission for ER-Phagy

Tuesday, February 19 | 5:00PM - 7:00PM
Autophagy Regulation and Processes
Room: Eldorado Grand Ballroom

Speaker 7 of 7
Vojo Deretic, University of New Mexico Health Sciences Center, USA
Autophagy Regulation by Galectins during Membrane Damage Homeostasis

Tuesday, February 19 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Cava Santa Fe
No registration fees are used to fund alcohol served at this function.

Tuesday, February 19 | 7:30PM - 10:00PM
Poster Session 2
Room: Cava Santa Fe


Wednesday, February 20 | 7:00AM - 8:00AM
Breakfast
Room: Cava Santa Fe


Wednesday, February 20 | 8:00AM - 11:00AM
Autophagy, Proteostasis and Organellar Homeostasis
Room: Eldorado Grand Ballroom

Speaker 1 of 8
* Eeva-Liisa Eskelinen, University of Turku, Finland

Wednesday, February 20 | 8:00AM - 11:00AM
Autophagy, Proteostasis and Organellar Homeostasis
Room: Eldorado Grand Ballroom

Speaker 2 of 8
Kevin M. Ryan, Beatson Institute for Cancer Research, UK
Autophagy in Tissue Growth and Tumor Development

Wednesday, February 20 | 8:00AM - 11:00AM
Autophagy, Proteostasis and Organellar Homeostasis
Room: Eldorado Grand Ballroom

Speaker 3 of 8
Jennifer A. Lippincott-Schwartz, Howard Hughes Medical Institute - Janelia Farm, USA
Cross-Talk between Lipid Droplets, Autophagy and Mitochondria Drives Cell Survival Under Starvation

Wednesday, February 20 | 8:00AM - 11:00AM
Autophagy, Proteostasis and Organellar Homeostasis
Room: Eldorado Grand Ballroom

Speaker 4 of 8
Martin Graef, Max Planck Institute for Biology of Aging, Germany
Short Talk: System-Wide Profiling of Mitotic Aging Reveals Pro-Aging Functions of the Autophagy Machinery

Wednesday, February 20 | 8:00AM - 11:00AM
Autophagy, Proteostasis and Organellar Homeostasis
Room: Eldorado Grand Ballroom


Coffee Break

Wednesday, February 20 | 8:00AM - 11:00AM
Autophagy, Proteostasis and Organellar Homeostasis
Room: Eldorado Grand Ballroom

Speaker 6 of 8
Tamotsu Yoshimori, Osaka University, Japan
Suppression of Autophagic Activity by Rubicon is a Signature of Aging

Wednesday, February 20 | 8:00AM - 11:00AM
Autophagy, Proteostasis and Organellar Homeostasis
Room: Eldorado Grand Ballroom

Speaker 7 of 8
Meagan J. McGrath, Monash University, Australia
Short Talk: Defective Lysosome Homeostasis during Autophagy Causes Skeletal Muscle Disease

Wednesday, February 20 | 8:00AM - 11:00AM
Autophagy, Proteostasis and Organellar Homeostasis
Room: Eldorado Grand Ballroom

Speaker 8 of 8
Anastasia Henry, Denali Therapeutics, USA
The Role of Leucine-Rich Repeat Kinase 2 (LRRK2) in Regulating Endo-Lysosomal Function

Wednesday, February 20 | 11:00AM - 5:00PM
On Own for Lunch


Wednesday, February 20 | 11:00AM - 1:00PM
Poster Setup
Room: Cava Santa Fe


Wednesday, February 20 | 1:00PM - 10:00PM
Poster Viewing
Room: Cava Santa Fe


Wednesday, February 20 | 2:30PM - 4:30PM
Panel: Women in Science at All Career Stages
Room: Eldorado Grand Ballroom

Speaker 1 of 7
* Anne Simonsen, University of Oslo, Norway

Wednesday, February 20 | 2:30PM - 4:30PM
Panel: Women in Science at All Career Stages
Room: Eldorado Grand Ballroom

Speaker 2 of 7
* Malene Hansen, Sanford Burnham Prebys Medical Discovery Institute, USA

Wednesday, February 20 | 2:30PM - 4:30PM
Panel: Women in Science at All Career Stages
Room: Eldorado Grand Ballroom

Speaker 3 of 7
Magdalene Moran, Rheostat Therapeutics, USA

Wednesday, February 20 | 2:30PM - 4:30PM
Panel: Women in Science at All Career Stages
Room: Eldorado Grand Ballroom

Speaker 4 of 7
Helin Vakifahmetoglu-Norberg, Karolinska Institutet, Sweden

Wednesday, February 20 | 2:30PM - 4:30PM
Panel: Women in Science at All Career Stages
Room: Eldorado Grand Ballroom

Speaker 5 of 7
Aurore L. Claude-Taupin, University of New Mexico, USA

Wednesday, February 20 | 2:30PM - 4:30PM
Panel: Women in Science at All Career Stages
Room: Eldorado Grand Ballroom

Speaker 6 of 7
Eun-Kyeong Jo, Chungnam National University, South Korea

Wednesday, February 20 | 2:30PM - 4:30PM
Panel: Women in Science at All Career Stages
Room: Eldorado Grand Ballroom

Speaker 7 of 7
Marie Bao, Cell Press, USA

Wednesday, February 20 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Wednesday, February 20 | 5:00PM - 7:00PM
Autophagy in Aging, Degenerative, and Inflammatory Disease
Room: Eldorado Grand Ballroom

Speaker 1 of 7
* Jennifer Martinez, NIEHS, National Institutes of Health, USA

Wednesday, February 20 | 5:00PM - 7:00PM
Autophagy in Aging, Degenerative, and Inflammatory Disease
Room: Eldorado Grand Ballroom

Speaker 2 of 7
* Phyllis I. Hanson, University of Michigan, USA

Wednesday, February 20 | 5:00PM - 7:00PM
Autophagy in Aging, Degenerative, and Inflammatory Disease
Room: Eldorado Grand Ballroom

Speaker 3 of 7
Malene Hansen, Sanford Burnham Prebys Medical Discovery Institute, USA
Regulation of Autophagy in Aging and Disease

Wednesday, February 20 | 5:00PM - 7:00PM
Autophagy in Aging, Degenerative, and Inflammatory Disease
Room: Eldorado Grand Ballroom

Speaker 4 of 7
Franck Oury, Institut Necker Enfants-Malades, France
Short Talk: Autophagy Induction is Required to Enhance Cognition and Integrate the Effects of Youthful Systemic Factors in the Aged Brain

Wednesday, February 20 | 5:00PM - 7:00PM
Autophagy in Aging, Degenerative, and Inflammatory Disease
Room: Eldorado Grand Ballroom

Speaker 5 of 7
Mondira Kundu, St. Jude Children's Hospital, USA
ULK/Atg1 Function: From Development to Disease

Wednesday, February 20 | 5:00PM - 7:00PM
Autophagy in Aging, Degenerative, and Inflammatory Disease
Room: Eldorado Grand Ballroom

Speaker 6 of 7
Rupert Beale, Francis Crick Institute, UK
Short Talk: Influenza A Virus Triggers a Pathway that Resembles Autophagy but Has a Distinct Molecular Basis

Wednesday, February 20 | 5:00PM - 7:00PM
Autophagy in Aging, Degenerative, and Inflammatory Disease
Room: Eldorado Grand Ballroom

Speaker 7 of 7
Herbert (Skip) W. Virgin, Vir Biotechnology, USA
Role of Autophagy and Autophagy Genes in Infection, Inflammation and Immunity

Wednesday, February 20 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Cava Santa Fe
No registration fees are used to fund alcohol served at this function.

Wednesday, February 20 | 7:30PM - 10:00PM
Poster Session 3
Room: Cava Santa Fe


Thursday, February 21 | 7:00AM - 8:00AM
Breakfast
Room: Cava Santa Fe


Thursday, February 21 | 8:00AM - 11:00AM
Autophagy in Metabolism, Growth Control and Cancer
Room: Eldorado Grand Ballroom

Speaker 1 of 9
* Devrim Gozuacik, Sabanci University, Turkey

Thursday, February 21 | 8:00AM - 11:00AM
Autophagy in Metabolism, Growth Control and Cancer
Room: Eldorado Grand Ballroom

Speaker 2 of 9
* Leon O. Murphy, Casma Therapeutics, USA

Thursday, February 21 | 8:00AM - 11:00AM
Autophagy in Metabolism, Growth Control and Cancer
Room: Eldorado Grand Ballroom

Speaker 3 of 9
Eileen P. White, Rutgers Cancer Institute of New Jersey, USA
Autophagy Maintains Host and Tumor Metabolism and an Anti-Cancer Immune Response

Thursday, February 21 | 8:00AM - 11:00AM
Autophagy in Metabolism, Growth Control and Cancer
Room: Eldorado Grand Ballroom

Speaker 4 of 9
Rushika M. Perera, University of California, San Francisco, USA
Short Talk: Lysosome Mediated Remodeling of the Cancer Proteome

Thursday, February 21 | 8:00AM - 11:00AM
Autophagy in Metabolism, Growth Control and Cancer
Room: Eldorado Grand Ballroom

Speaker 5 of 9
Tor Erik Rusten, Institute for Cancer Research, Norway
Autophagy and Cancer: What Flies Tell Us

Thursday, February 21 | 8:00AM - 11:00AM
Autophagy in Metabolism, Growth Control and Cancer
Room: Eldorado Grand Ballroom


Coffee Break

Thursday, February 21 | 8:00AM - 11:00AM
Autophagy in Metabolism, Growth Control and Cancer
Room: Eldorado Grand Ballroom

Speaker 7 of 9
Beat Nyfeler, Novartis Institutes for BioMedical Research, Switzerland
VPS34 and Autolysosomal Regulation


Thursday, February 21 | 8:00AM - 11:00AM
Autophagy in Metabolism, Growth Control and Cancer
Room: Eldorado Grand Ballroom

Speaker 8 of 9
Nunzia Pastore, Baylor College of Medicine, USA
Short Talk: MiT-TFE Transcription Factors Couple Autophagy and Metabolism to the Peripheral Clock

Thursday, February 21 | 8:00AM - 11:00AM
Autophagy in Metabolism, Growth Control and Cancer
Room: Eldorado Grand Ballroom

Speaker 9 of 9
Jayanta Debnath, University of California, San Francisco, USA
Autophagy and Metastatic Colonization

Thursday, February 21 | 11:00AM - 5:00PM
On Own for Lunch


Thursday, February 21 | 2:30PM - 4:30PM
Workshop 2: Current Controversies
Room: Eldorado Grand Ballroom

Speaker 1 of 5
* Michael Lazarou, Monash University, Australia
Function of Mammalian Atg8s (LC3s and GABARAPs) in Autophagy: New Insights and Controversies

Thursday, February 21 | 2:30PM - 4:30PM
Workshop 2: Current Controversies
Room: Eldorado Grand Ballroom

Speaker 2 of 5
Shigeomi Shimizu, Tokyo Medical and Dental University, Japan
New Insights into the Mechanism and Biological Roles of Atg5-Independent Macroautophagy

Thursday, February 21 | 2:30PM - 4:30PM
Workshop 2: Current Controversies
Room: Eldorado Grand Ballroom

Speaker 3 of 5
Shenliang Yu, UCSF, USA
ATG2 Is a Lipid Transporter at ER-Autophagosome Contacts during Autophagosome Biogenesis

Thursday, February 21 | 2:30PM - 4:30PM
Workshop 2: Current Controversies
Room: Eldorado Grand Ballroom

Speaker 4 of 5
Richard I. Odle, Babraham Institute, UK
Repression of Autophagy and Phosphorylation of Autophagy Regulators during Mitosis Is Independent of mTORC1

Thursday, February 21 | 2:30PM - 4:30PM
Workshop 2: Current Controversies
Room: Eldorado Grand Ballroom

Speaker 5 of 5
Helin Vakifahmetoglu-Norberg, Karolinska Institutet, Sweden
Targetome Analysis of Chaperone-Mediated Autophagy in Cancer Cells

Thursday, February 21 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Thursday, February 21 | 5:00PM - 7:00PM
Autophagy from Model Systems to Humans - Closing the Circle
Room: Eldorado Grand Ballroom

Speaker 1 of 7
* Quan Chen, Nankai University, China

Thursday, February 21 | 5:00PM - 7:00PM
Autophagy from Model Systems to Humans - Closing the Circle
Room: Eldorado Grand Ballroom

Speaker 2 of 7
* Zvulun Elazar, Weizmann Institute of Science, Israel

Thursday, February 21 | 5:00PM - 7:00PM
Autophagy from Model Systems to Humans - Closing the Circle
Room: Eldorado Grand Ballroom

Speaker 3 of 7
Angela Ianniciello, University of Glasgow, UK
Short Talk: ULK1 Regulates Central Carbon Metabolism and Drug-Sensitivity in Leukemic Stem Cells in Autophagy-Independent and Autophagy-Dependent Manner

Thursday, February 21 | 5:00PM - 7:00PM
Autophagy from Model Systems to Humans - Closing the Circle
Room: Eldorado Grand Ballroom

Speaker 4 of 7
Hong Zhang, Chinese Academy of Sciences, China
Ciliated Sensory Neurons Detect Cuticle Damage in C. elegans and Activate Autophagy in Multiple Tissues via a TGFbeta-AMPK Axis

Thursday, February 21 | 5:00PM - 7:00PM
Autophagy from Model Systems to Humans - Closing the Circle
Room: Eldorado Grand Ballroom

Speaker 5 of 7
Eric H. Baehrecke, University of Massachusetts Medical School, USA
Discovery of Novel Regulators of Autophagy in Animals

Thursday, February 21 | 5:00PM - 7:00PM
Autophagy from Model Systems to Humans - Closing the Circle
Room: Eldorado Grand Ballroom

Speaker 6 of 7
Ai Yamamoto, Columbia University, USA
Short Talk: The Physiologic Cargoes of Macroautophagy in Aging and Disease

Thursday, February 21 | 5:00PM - 7:00PM
Autophagy from Model Systems to Humans - Closing the Circle
Room: Eldorado Grand Ballroom

Speaker 7 of 7
Andrew M. Thorburn, University of Colorado AMC, USA
Targeting Autophagy in Cancer Treatment

Thursday, February 21 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions
Room: Eldorado Grand Ballroom


Thursday, February 21 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Cava Santa Fe
No registration fees are used to fund alcohol served at this function.

Thursday, February 21 | 8:00PM - 11:00PM
Entertainment
Room: Cava Santa Fe
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, February 21 | 8:00PM - 11:00PM
Cash Bar
Room: Cava Santa Fe


Friday, February 22 | 10:24AM - 10:24AM
Departure


*Session Chair.