Web Desc
Mammalian Sensory Systems
Organizer(s): Stephen Liberles, David D. Ginty, Jeffrey R. Holt and Melanie Samuel
Date: March 15 - 19, 2019
Location: Allen Institute, Seattle, WA, USA
Sponsored by Allen Institute and Merck & Co., Inc.
Summary of Meeting:
Our basic external sensory systems - touch, taste, vision, hearing and smell - enable us to perceive the world around us, and other internal sensory systems enable us to perceive the secret world within us. Recent advances have revealed the molecular logic of how some sensory systems work, while other sensory systems remain uncharted. Fields of sensory biology often maintain separate cultures, and are at varying levels of maturity, with different frontiers, unknowns and perspectives. This conference brings leading experts from different sensory fields together, and reviews conceptual and technical advances achieved in one sensory system that may enable new findings in others. It highlights recent advances in each external sense: vision, olfaction, taste, hearing and touch/pain/temperature sensation, as well as new developments in the emerging field of internal organ sensation. Topics include: 1) Receptors and sensory mechanisms, 2) Neural circuits, 3) Behavioral and physiological responses, and 4) The genetic basis of sensory deficits.
Scholarship Deadline: November 28 2018
Discounted Abstract Deadline: November 28 2018
Abstract Deadline: December 11 2018
Discounted Registration Deadline: January 17 2019
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Allen InstituteMerck & Co., Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Institute on Deafness and Other Communication Disorders (NIDCD)
Grant No. 1R13DC017643-01
Funding for this conference was made possible (in part) by 1R13DC017643-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Friday, March 15 | 4:00PM - 8:00PM
Arrival and Registration
Room: Lobby


Friday, March 15 | 6:00PM - 8:00PM
Welcome Mixer
Room: Atrium
No registration fees are used to fund alcohol served at this function.

Saturday, March 16 | 8:00AM - 9:00AM
Breakfast
Room: Atrium


Saturday, March 16 | 8:30AM - 9:00AM
Poster Setup
Room: 2nd Floor


Saturday, March 16 | 9:00AM - 5:00PM
Poster Viewing
Room: 2nd Floor


Saturday, March 16 | 9:00AM - 10:00AM
Welcome and Keynote Address
Room: Auditorium

Speaker 1 of 2
* Stephen Liberles, Harvard Medical School, USA

Saturday, March 16 | 9:00AM - 10:00AM
Welcome and Keynote Address
Room: Auditorium

Speaker 2 of 2
Richard Axel, Columbia University, USA
Central Representations of Odors

Saturday, March 16 | 10:00AM - 1:00PM
Structure and Function of Chemoreceptors
Room: Auditorium

Speaker 1 of 8
* Stephen Liberles, Harvard Medical School, USA

Saturday, March 16 | 10:00AM - 1:00PM
Structure and Function of Chemoreceptors
Room: Auditorium

Speaker 2 of 8
Emily Liman, University of Southern California, USA
Ion Channels for Sour Taste

Saturday, March 16 | 10:00AM - 1:00PM
Structure and Function of Chemoreceptors
Room: Auditorium


Coffee Break

Saturday, March 16 | 10:00AM - 1:00PM
Structure and Function of Chemoreceptors
Room: Auditorium

Speaker 4 of 8
Xinzhong Dong, Johns Hopkins University, USA
Mrgs in Itch Sensation

Saturday, March 16 | 10:00AM - 1:00PM
Structure and Function of Chemoreceptors
Room: Auditorium

Speaker 5 of 8
Paul L. Greer, University of Massachusetts Medical School, USA
Exteroceptive and Interoceptive Chemosensation by MS4A Receptors

Saturday, March 16 | 10:00AM - 1:00PM
Structure and Function of Chemoreceptors
Room: Auditorium

Speaker 6 of 8
Kazushige Touhara, University of Tokyo, Japan
Molecular, Receptor, and Neural Basis for Chemosensory Signal-Mediated Behavior and Emotion in Mice

Saturday, March 16 | 10:00AM - 1:00PM
Structure and Function of Chemoreceptors
Room: Auditorium

Speaker 7 of 8
Isaac Chiu, Harvard Medical School, USA
Short Talk: Sensory Neuron Interactions with Bacteria in Immunity and Pain

Saturday, March 16 | 10:00AM - 1:00PM
Structure and Function of Chemoreceptors
Room: Auditorium

Speaker 8 of 8
Hitoshi Sakano, University of Fukui, Japan
Short Talk: Sema7A/PlxnC1 Signaling Mediates Olfactory Imprinting during the Critical Period in Mice

Saturday, March 16 | 1:00PM - 2:00PM
Lunch
Room: Atrium


Saturday, March 16 | 1:15PM - 3:15PM
Poster Session 1
Room: 2nd Floor


Saturday, March 16 | 3:15PM - 4:45PM
Workshop 1
Room: Auditorium

Speaker 1 of 7
David D. Ginty, HHMI/Harvard Medical School, USA

Saturday, March 16 | 3:15PM - 4:45PM
Workshop 1
Room: Auditorium

Speaker 2 of 7
Swetha Murthy, The Scripps Research Institute, USA
OSCA/TMEM63 Are an Evolutionarily Conserved Family of Mechanically Activated Ion Channels

Saturday, March 16 | 3:15PM - 4:45PM
Workshop 1
Room: Auditorium

Speaker 3 of 7
Naresh Hanchate, Fred Hutchinson Cancer Research Center, USA
Connect-seq to Superimpose Molecular on Anatomical Neural Circuit Maps

Saturday, March 16 | 3:15PM - 4:45PM
Workshop 1
Room: Auditorium

Speaker 4 of 7
Esther Borges Florsheim, Yale University School of Medicine, USA
Immune-Mediated Allergen Sensing Controls Avoidance Behavior

Saturday, March 16 | 3:15PM - 4:45PM
Workshop 1
Room: Auditorium

Speaker 5 of 7
Chuchu Zhang, Harvard Medical School, USA
Molecular Dissection of the Area Postrema and its Role in Nausea

Saturday, March 16 | 3:15PM - 4:45PM
Workshop 1
Room: Auditorium

Speaker 6 of 7
Fred Schwaller, Max Delbruck Centrum, Germany
Ush2A Is a Cutaneous Vibration Sensor in Mouse and Man

Saturday, March 16 | 3:15PM - 4:45PM
Workshop 1
Room: Auditorium

Speaker 7 of 7
Annie Handler, Rockefeller University, USA
Distinct Dopamine Receptor Pathways Underlie the Temporal Sensitivity of Olfactory Associative Learning

Saturday, March 16 | 4:45PM - 5:00PM
Coffee Available
Room: Atrium


Saturday, March 16 | 5:00PM - 7:00PM
Structure and Function of Mechanoreceptors
Room: Auditorium

Speaker 1 of 6
* Melanie Samuel, Baylor College of Medicine, USA

Saturday, March 16 | 5:00PM - 7:00PM
Structure and Function of Mechanoreceptors
Room: Auditorium

Speaker 2 of 6
David Julius, University of California, San Francisco, USA
Natural Products as Probes of the Pain Pathway: From Physiology to Atomic Structure

Saturday, March 16 | 5:00PM - 7:00PM
Structure and Function of Mechanoreceptors
Room: Auditorium

Speaker 3 of 6
Ardem Patapoutian, The Scripps Research Institute, USA
How do you Feel the Force?


Saturday, March 16 | 5:00PM - 7:00PM
Structure and Function of Mechanoreceptors
Room: Auditorium

Speaker 4 of 6
Jeffrey R. Holt, Boston Children's Hospital, USA
Function, Dysfunction and Restoration of TMC Channels in the Inner Ear

Saturday, March 16 | 5:00PM - 7:00PM
Structure and Function of Mechanoreceptors
Room: Auditorium

Speaker 5 of 6
David A. Yarmolinsky, Boston Children's Hospital, USA
Short Talk: Optical Analysis of Spontaneous Nociception

Saturday, March 16 | 5:00PM - 7:00PM
Structure and Function of Mechanoreceptors
Room: Auditorium

Speaker 6 of 6
Gregory Bryman, Harvard Medical School, USA
Short Talk: High-Fidelity Signal Transmission through Foveal Photoreceptors

Saturday, March 16 | 7:00PM - 7:00PM
On Own for Dinner


Sunday, March 17 | 8:00AM - 9:00AM
Breakfast
Room: Atrium


Sunday, March 17 | 8:30AM - 9:00AM
Poster Setup
Room: 2nd Floor


Sunday, March 17 | 9:00AM - 5:00PM
Poster Viewing
Room: 2nd Floor


Sunday, March 17 | 9:00AM - 12:00PM
Cell Biology of Sensory Neurons
Room: Auditorium

Speaker 1 of 8
* Kara Marshall, The Scripps Research Institute, USA

Sunday, March 17 | 9:00AM - 12:00PM
Cell Biology of Sensory Neurons
Room: Auditorium

Speaker 2 of 8
Lisa Stowers, The Scripps Research, USA
Hormonal Control of Pheromone-Sensing Neurons

Sunday, March 17 | 9:00AM - 12:00PM
Cell Biology of Sensory Neurons
Room: Auditorium

Speaker 3 of 8
Melanie Samuel, Baylor College of Medicine, USA
The Molecular Basis of Retina Development and Repair

Sunday, March 17 | 9:00AM - 12:00PM
Cell Biology of Sensory Neurons
Room: Auditorium


Coffee Break

Sunday, March 17 | 9:00AM - 12:00PM
Cell Biology of Sensory Neurons
Room: Auditorium

Speaker 5 of 8
Brendan Lehnert, Harvard Medical School, USA
Synaptic Expansion Scales the Representation of the Body in the Brain

Sunday, March 17 | 9:00AM - 12:00PM
Cell Biology of Sensory Neurons
Room: Auditorium

Speaker 6 of 8
Nirupa Chaudhari, University of Miami Miller School of Medicine, USA
Short Talk: Putative Hybrid Chemosensory-Mechanosensory Neurons Innervate Taste Buds

Sunday, March 17 | 9:00AM - 12:00PM
Cell Biology of Sensory Neurons
Room: Auditorium

Speaker 7 of 8
Wendy W.S. Yue, University of California, San Francisco, USA
Short Talk: Toward in vivo Optical Imaging of Trigeminal Ganglion Neurons and Afferents

Sunday, March 17 | 9:00AM - 12:00PM
Cell Biology of Sensory Neurons
Room: Auditorium

Speaker 8 of 8
Joriene C. de Nooij, Columbia University, USA
Short Talk: Molecular Correlates of Muscle Spindle and Golgi Tendon Organ Sensory Afferents

Sunday, March 17 | 12:00PM - 1:00PM
Lunch
Room: Atrium


Sunday, March 17 | 12:45PM - 2:45PM
Poster Session 2
Room: 2nd Floor


Sunday, March 17 | 2:45PM - 3:00PM
Coffee Available
Room: Atrium


Sunday, March 17 | 3:00PM - 5:00PM
Genetic and Translational Approaches for Sensory Deficits
Room: Auditorium

Speaker 1 of 5
* Alan J. Emanuel, Harvard Medical School, USA

Sunday, March 17 | 3:00PM - 5:00PM
Genetic and Translational Approaches for Sensory Deficits
Room: Auditorium

Speaker 2 of 5
Alexander Chesler, NCCIH, National Institutes of Health, USA
The Role of PIEZO2 in Health and Disease

Sunday, March 17 | 3:00PM - 5:00PM
Genetic and Translational Approaches for Sensory Deficits
Room: Auditorium

Speaker 3 of 5
Karen B. Avraham, Tel Aviv University, Israel
Epigenomics of the Auditory System

Sunday, March 17 | 3:00PM - 5:00PM
Genetic and Translational Approaches for Sensory Deficits
Room: Auditorium

Speaker 4 of 5
Andrew D. Huberman, Stanford University School of Medicine, USA
Circuits for Merging External and Internal Sensations to Drive Adaptive Behavior

Sunday, March 17 | 3:00PM - 5:00PM
Genetic and Translational Approaches for Sensory Deficits
Room: Auditorium

Speaker 5 of 5
David Shelton, USA
Therapeutic Approaches to Chronic Pain

Sunday, March 17 | 5:00PM - 5:00PM
On Own for Dinner


Monday, March 18 | 8:00AM - 9:00AM
Breakfast
Room: Atrium


Monday, March 18 | 8:30AM - 9:00AM
Poster Setup
Room: 2nd Floor


Monday, March 18 | 9:00AM - 5:00PM
Poster Viewing
Room: 2nd Floor


Monday, March 18 | 9:00AM - 12:00PM
Evolution of Sensory Systems
Room: Auditorium

Speaker 1 of 8
* Paul L. Greer, University of Massachusetts Medical School, USA

Monday, March 18 | 9:00AM - 12:00PM
Evolution of Sensory Systems
Room: Auditorium

Speaker 2 of 8
Kenneth C. Catania, Vanderbilt University, USA
Touch and Olfaction at the Extreme: Surprising Insights From Nature’s Specialists

Monday, March 18 | 9:00AM - 12:00PM
Evolution of Sensory Systems
Room: Auditorium

Speaker 3 of 8
Maude Baldwin, Max Planck Institute for Ornithology, Germany
Evolving Sweet Taste Receptors

Monday, March 18 | 9:00AM - 12:00PM
Evolution of Sensory Systems
Room: Auditorium


Coffee Break

Monday, March 18 | 9:00AM - 12:00PM
Evolution of Sensory Systems
Room: Auditorium

Speaker 5 of 8
Elena O. Gracheva, Yale University School of Medicine, USA
Molecular Adaptations to the Unique Lifestyle in Mammalian Hibernators

Monday, March 18 | 9:00AM - 12:00PM
Evolution of Sensory Systems
Room: Auditorium

Speaker 6 of 8
Slav Bagriantsev, Yale University, USA
Short Talk: Molecular basis of Mechanosensory Adaptations in Tactile Specialist Birds

Monday, March 18 | 9:00AM - 12:00PM
Evolution of Sensory Systems
Room: Auditorium

Speaker 7 of 8
Kali Esancy, University of Washington, USA
Short Talk: A Multi-Species Model for Selective Pruritus via the Direct Activation of TRPA1

Monday, March 18 | 9:00AM - 12:00PM
Evolution of Sensory Systems
Room: Auditorium

Speaker 8 of 8
Veronica Jové, Rockefeller University, USA
Short Talk: The Taste of Blood

Monday, March 18 | 12:00PM - 1:00PM
Lunch
Room: Atrium


Monday, March 18 | 12:30PM - 2:30PM
Poster Session 3
Room: 2nd Floor


Monday, March 18 | 2:30PM - 3:00PM
Coffee Available
Room: Atrium


Monday, March 18 | 3:00PM - 5:00PM
Early Sensory Processing
Room: Auditorium

Speaker 1 of 5
* David A. Yarmolinsky, Boston Children's Hospital, USA

Monday, March 18 | 3:00PM - 5:00PM
Early Sensory Processing
Room: Auditorium

Speaker 2 of 5
Diana Bautista, University of California, Berkeley, USA
Neuroimmune Mechanisms Driving Changes in Sensory Behaviors

Monday, March 18 | 3:00PM - 5:00PM
Early Sensory Processing
Room: Auditorium

Speaker 3 of 5
Ellen A. Lumpkin, University of California, Berkeley, USA
Epithelial-Neural Crosstalk in Touch Reception

Monday, March 18 | 3:00PM - 5:00PM
Early Sensory Processing
Room: Auditorium

Speaker 4 of 5
Marla Feller, University of California, Berkeley, USA
Organization and Development of Retinal Circuits Mediating Direction Selectivity

Monday, March 18 | 3:00PM - 5:00PM
Early Sensory Processing
Room: Auditorium

Speaker 5 of 5
Fan Wang, Massachusetts Institute of Technology, USA
A Central Analgesic Circuit in the Amygdala

Monday, March 18 | 5:00PM - 5:00PM
On Own for Dinner


Tuesday, March 19 | 8:00AM - 9:00AM
Breakfast
Room: Atrium


Tuesday, March 19 | 9:00AM - 12:00PM
Sensory Control of Limbic and Autonomic Systems
Room: Auditorium

Speaker 1 of 8
* Maude Baldwin, Max Planck Institute for Ornithology, Germany

Tuesday, March 19 | 9:00AM - 12:00PM
Sensory Control of Limbic and Autonomic Systems
Room: Auditorium

Speaker 2 of 8
Linda B. Buck, Fred Hutchinson Cancer Research Center, USA
Odor Effects on Stress

Tuesday, March 19 | 9:00AM - 12:00PM
Sensory Control of Limbic and Autonomic Systems
Room: Auditorium

Speaker 3 of 8
Nirao Shah, Stanford University, USA
A Neural Pathway for Innate Gender Recognition

Tuesday, March 19 | 9:00AM - 12:00PM
Sensory Control of Limbic and Autonomic Systems
Room: Auditorium


Coffee Break

Tuesday, March 19 | 9:00AM - 12:00PM
Sensory Control of Limbic and Autonomic Systems
Room: Auditorium

Speaker 5 of 8
Sara L. Prescott, Harvard Medical School, USA
Diversity of Upper Airway Sensory Neurons

Tuesday, March 19 | 9:00AM - 12:00PM
Sensory Control of Limbic and Autonomic Systems
Room: Auditorium

Speaker 6 of 8
Xin Sun, University of California, San Diego, USA
Short Talk: Neuroendocrine Cells in Lung Sensory Function

Tuesday, March 19 | 9:00AM - 12:00PM
Sensory Control of Limbic and Autonomic Systems
Room: Auditorium

Speaker 7 of 8
Yin Liu, Stanford University, USA
Short Talk: Molecular and Functional Diversity of Pulmonary Sensory Neurons Revealed by Single-Cell RNA Sequencing

Tuesday, March 19 | 9:00AM - 12:00PM
Sensory Control of Limbic and Autonomic Systems
Room: Auditorium

Speaker 8 of 8
Lisa Beutler, University of California, San Francisco, USA
Short Talk: An Obesogenic Diet Modulates Gut-Brain Communication

Tuesday, March 19 | 12:00PM - 12:15PM
Program Officer for BRAIN
Room: Auditorium

Speaker 1 of 1
* Karen K. David, NINDS, National Institutes of Health, USA

Tuesday, March 19 | 12:00PM - 5:00PM
On Own for Lunch


Tuesday, March 19 | 3:00PM - 4:30PM
Workshop 2
Room: Auditorium

Speaker 1 of 7
* Jeffrey R. Holt, Boston Children's Hospital, USA

Tuesday, March 19 | 3:00PM - 4:30PM
Workshop 2
Room: Auditorium

Speaker 2 of 7
Wen Mai Wong, University of Texas Southwestern Medical Center, USA
Physiology-Forward Identification of Sensitive and Selective Bile Acid Receptors in the Vomeronasal Organ

Tuesday, March 19 | 3:00PM - 4:30PM
Workshop 2
Room: Auditorium

Speaker 3 of 7
Lujing Chen, Johns Hopkins University, USA
Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically-Photosensitive Retinal Ganglion Cells

Tuesday, March 19 | 3:00PM - 4:30PM
Workshop 2
Room: Auditorium

Speaker 4 of 7
Gen-ichi Tasaka, Hebrew University of Jerusalem, Israel
The Temporal Association Cortex Is Involved in Auditory-Driven Maternal Plasticity

Tuesday, March 19 | 3:00PM - 4:30PM
Workshop 2
Room: Auditorium

Speaker 5 of 7
Robin F. Krimm, University of Louisville School of Medicine, USA
Anatomical Underpinnings of Broadly and Narrowly Tuned Taste Neurons

Tuesday, March 19 | 3:00PM - 4:30PM
Workshop 2
Room: Auditorium

Speaker 6 of 7
Alejandra Fernandez, Oregon Health & Science University, USA
Role of PTEN in Somatosensory Development

Tuesday, March 19 | 3:00PM - 4:30PM
Workshop 2
Room: Auditorium

Speaker 7 of 7
Seungwon Choi, Harvard Medical School, USA
Genetic Dissection of Ascending Touch and Pain Pathways of the Anterolateral Tract

Tuesday, March 19 | 4:30PM - 5:00PM
Coffee Available
Room: Atrium


Tuesday, March 19 | 5:00PM - 7:00PM
Cortical Processing of Sensory Information
Room: Auditorium

Speaker 1 of 5
* Chen Ran, Harvard University, USA

Tuesday, March 19 | 5:00PM - 7:00PM
Cortical Processing of Sensory Information
Room: Auditorium

Speaker 2 of 5
Shawn Olsen, Allen Institute for Brain Science, USA
Multi-Regional Cortical and Thalamic Networks of the Mouse Visual System

Tuesday, March 19 | 5:00PM - 7:00PM
Cortical Processing of Sensory Information
Room: Auditorium

Speaker 3 of 5
Stephen D. Roper, University of Miami, USA
The Logic of Taste: Is It Really So Logical?

Tuesday, March 19 | 5:00PM - 7:00PM
Cortical Processing of Sensory Information
Room: Auditorium

Speaker 4 of 5
Gloria Choi, Massachusetts Institute of Technology, USA
Cortical Dysfunction and Social Behaviors

Tuesday, March 19 | 5:00PM - 7:00PM
Cortical Processing of Sensory Information
Room: Auditorium

Speaker 5 of 5
Daniel Feldman, University of California, Berkeley, USA
Maps and Neural Codes in Whisker Somatosensory Cortex

Tuesday, March 19 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Auditorium


Tuesday, March 19 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Courtyard by Marriott/Lake Union
No registration fees are used to fund alcohol served at this function.

Tuesday, March 19 | 8:00PM - 11:00PM
Entertainment
Room: Courtyard by Marriott/Lake Union
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Tuesday, March 19 | 8:00PM - 11:00PM
Cash Bar
Room: Courtyard by Marriott/Lake Union


Wednesday, March 20 | 10:24AM - 10:24AM
Departure


*Session Chair.