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Web Desc
Positive-Strand RNA Viruses
Organizer(s): Frank van Kuppeveld and Andrea Gamarnik
Date: June 09 - 13, 2019
Location: INEC Killarney Convention Centre, Killarney, Co. Kerry, Ireland
Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation
Summary of Meeting:
The Keystone Symposia conference on positive-strand RNA viruses provides an international forum for research on human, animal, insect, plant and bacterial viruses with positive-strand RNA genomes. This group of viruses contains many clinically relevant and well-known pathogens (e.g., poliovirus, hepatitis C virus, Dengue and West Nile virus). Furthermore, the enormous diversity of positive-strand RNA viruses in animals and insects, combined with their evolutionary and adaptive potential following a species-jump, poses a threat to the human population as demonstrated by the growing list of emerging viruses, including zoonotic as well as arbovirus-transmitted pathogens such as MERS-CoV, Chikungunya and Zika virus. Detailed insight into the “virosphere”, the “virome”, viral evolution, as well as in the molecular details of viral replication and spreading, tissue tropism, and viral recognition by the host immune system is critical to understand virus transmission, viral pathogenesis as well as to develop novel therapeutic and preventive measures. This conference brings together experienced and junior experts to discuss the latest developments in molecular biology, cell biology, vector biology, immunology, vaccinology, and antiviral drug development applied to the field of positive-strand RNA viruses.
Global Health Travel Award Deadline: January 8 2019
Scholarship Deadline: February 7 2019
Discounted Abstract Deadline: February 7 2019
Abstract Deadline: March 6 2019
Discounted Registration Deadline: April 9 2019
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Bill & Melinda Gates Foundation
We gratefully acknowledge additional support from these exhibitors at this conference:
European Virus Archive
We gratefully acknowledge additional support for this conference from:
American Society of Gene & Cell Therapy (ASGCT)GeneTex, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI145246-01
Funding for this conference was made possible (in part) by 1R13AI145246-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, June 09 | 4:00PM - 8:00PM
Arrival and Registration
Room: INEC Foyer


Sunday, June 09 | 6:00PM - 8:00PM
Welcome Mixer
Room: INEC Foyer
No registration fees are used to fund alcohol served at this function.

Monday, June 10 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: INEC Main Auditorium

Speaker 3 of 3
Michael S. Diamond, Washington University School of Medicine, USA
Receptor Hunting for Alphaviruses: A Travel Through Time

Monday, June 10 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: INEC Main Auditorium

Speaker 2 of 3
* Andrea Gamarnik, Fundación Instituto Leloir, Argentina

Monday, June 10 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: INEC Main Auditorium

Speaker 1 of 3
* Frank van Kuppeveld, Utrecht University, Netherlands

Monday, June 10 | 9:30AM - 11:45AM
The Virosphere and the Virome
Room: INEC Main Auditorium

Speaker 7 of 7
Vyacheslav Yurchenko, University of Ostrava, Czech Republic
Short Talk: Positive-Strand RNA Viruses in Trypanosomatid Parasites

Monday, June 10 | 9:30AM - 11:45AM
The Virosphere and the Virome
Room: INEC Main Auditorium

Speaker 6 of 7
Marilyn J. Roossinck, Pennsylvania State University, USA
Viruses as Symbionts

Monday, June 10 | 9:30AM - 11:45AM
The Virosphere and the Virome
Room: INEC Main Auditorium

Speaker 5 of 7
Julie K. Pfeiffer, University of Texas Southwestern Medical Center, USA
Origins of Animal Innate Immunity

Monday, June 10 | 9:30AM - 11:45AM
The Virosphere and the Virome
Room: INEC Main Auditorium


Coffee Break

Monday, June 10 | 9:30AM - 11:45AM
The Virosphere and the Virome
Room: INEC Main Auditorium

Speaker 3 of 7
Eugene V. Koonin, National Institutes of Health, USA
Origins and Evolution of the Global RNA Virome

Monday, June 10 | 9:30AM - 11:45AM
The Virosphere and the Virome
Room: INEC Main Auditorium

Speaker 2 of 7
* Andrew E. Firth, University of Cambridge, UK

Monday, June 10 | 9:30AM - 11:45AM
The Virosphere and the Virome
Room: INEC Main Auditorium

Speaker 1 of 7
* Alexander E. Gorbalenya, Leiden University Medical Center, Netherlands

Monday, June 10 | 11:45AM - 1:00PM
Poster Setup
Room: 1st Floor INEC


Monday, June 10 | 11:45AM - 5:00PM
On Own for Lunch


Monday, June 10 | 1:00PM - 10:00PM
Poster Viewing
Room: 1st Floor INEC


Monday, June 10 | 2:30PM - 4:30PM
Workshop 1: Burning Questions, Opportunities and Challenges
in RNA Virology
Room: INEC Main Auditorium

Speaker 5 of 5
Ann Palmenberg, University of Wisconsin-Madison, USA
Women: Plurality or Equality?

Monday, June 10 | 2:30PM - 4:30PM
Workshop 1: Burning Questions, Opportunities and Challenges
in RNA Virology
Room: INEC Main Auditorium

Speaker 4 of 5
Drew Weissman, University of Pennsylvania, USA
mRNA-Based Vaccines and Therapeutics – Advances and Challenges

Monday, June 10 | 2:30PM - 4:30PM
Workshop 1: Burning Questions, Opportunities and Challenges
in RNA Virology
Room: INEC Main Auditorium

Speaker 3 of 5
Peter Sarnow, Stanford University School of Medicine, USA
Changing the Shape of Viral RNA to Subvert Host Pathways

Monday, June 10 | 2:30PM - 4:30PM
Workshop 1: Burning Questions, Opportunities and Challenges
in RNA Virology
Room: INEC Main Auditorium

Speaker 2 of 5
Ralf Bartenschlager, Heidelberg University, Germany
Resolved and Future Research Challenges of Plus-Strand RNA Virus Replication Strategies

Monday, June 10 | 2:30PM - 4:30PM
Workshop 1: Burning Questions, Opportunities and Challenges
in RNA Virology
Room: INEC Main Auditorium

Speaker 1 of 5
* Eric J. Snijder, Leiden University Medical Center, Netherlands

Monday, June 10 | 4:30PM - 5:00PM
Coffee Available
Room: INEC Foyer


Monday, June 10 | 5:00PM - 7:00PM
Virus Structure and Entry
Room: INEC Main Auditorium

Speaker 3 of 7
David Veesler, University of Washington, USA
Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

Monday, June 10 | 5:00PM - 7:00PM
Virus Structure and Entry
Room: INEC Main Auditorium

Speaker 2 of 7
* Berend Jan Bosch, Utrecht University, Netherlands

Monday, June 10 | 5:00PM - 7:00PM
Virus Structure and Entry
Room: INEC Main Auditorium

Speaker 1 of 7
* Toby Tuthill, Pirbright Institute, UK

Monday, June 10 | 5:00PM - 7:00PM
Virus Structure and Entry
Room: INEC Main Auditorium

Speaker 4 of 7
Shee Mei Lok, Singapore
Capsid Protein Structure in Zika Virus Reveals the Flavivirus Assembly Process

Monday, June 10 | 5:00PM - 7:00PM
Virus Structure and Entry
Room: INEC Main Auditorium

Speaker 5 of 7
Richard J. Kuhn, Purdue University, USA
Short Talk: Budding Induces Symmetry Defects in Flavivirus Virions

Monday, June 10 | 5:00PM - 7:00PM
Virus Structure and Entry
Room: INEC Main Auditorium

Speaker 6 of 7
Yifei Lang, Utrecht University, Netherlands
Short Talk: Betacoronavirus S and HE Proteins are in Functional Balance: Evidence for Convergent Evolution of Betacorona and Influenza Viruses

Monday, June 10 | 5:00PM - 7:00PM
Virus Structure and Entry
Room: INEC Main Auditorium

Speaker 7 of 7
Kelly Watters, University of Wisconsin, USA
Short Talk: CDHR3 Extracellular Domain EC1 Mediates Rhinovirus C Attachment to Cells and its Recombinant Derivatives Inhibit Virus Infection

Monday, June 10 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: INEC Foyer
No registration fees are used to fund alcohol served at this function.

Monday, June 10 | 7:30PM - 10:00PM
Poster Session 1
Room: 1st Floor INEC


Tuesday, June 11 | 8:30AM - 11:30AM
RNA Structure and Function
Room: INEC Main Auditorium

Speaker 1 of 9
* Diego Alvarez, Universidad Nacional de San Martín, Argentina

Tuesday, June 11 | 8:30AM - 11:30AM
RNA Structure and Function
Room: INEC Main Auditorium

Speaker 2 of 9
* Ian Goodfellow, University of Cambridge, UK

Tuesday, June 11 | 8:30AM - 11:30AM
RNA Structure and Function
Room: INEC Main Auditorium

Speaker 3 of 9
Andrea Gamarnik, Fundación Instituto Leloir, Argentina
Function and Evolution of RNA Structures in the Flavivirus Genome

Tuesday, June 11 | 8:30AM - 11:30AM
RNA Structure and Function
Room: INEC Main Auditorium

Speaker 4 of 9
Jeffrey S. Kieft, University of Colorado School of Medicine, USA
Understanding Viral RNA Function by Linking Structural Biology to Virology

Tuesday, June 11 | 8:30AM - 11:30AM
RNA Structure and Function
Room: INEC Main Auditorium


Coffee Break

Tuesday, June 11 | 8:30AM - 11:30AM
RNA Structure and Function
Room: INEC Main Auditorium

Speaker 6 of 9
Stacy M. Horner, Duke University Medical Center, USA
RNA Modifications Go Viral

Tuesday, June 11 | 8:30AM - 11:30AM
RNA Structure and Function
Room: INEC Main Auditorium

Speaker 7 of 9
Anna Marie Pyle, Yale University, USA
Regulatory Structures in Viral RNA Genomes

Tuesday, June 11 | 8:30AM - 11:30AM
RNA Structure and Function
Room: INEC Main Auditorium

Speaker 8 of 9
Omer Ziv, University of Cambridge, UK
Short Talk: RNA Communication between Viruses and their Hosts

Tuesday, June 11 | 8:30AM - 11:30AM
RNA Structure and Function
Room: INEC Main Auditorium

Speaker 9 of 9
Rebecca S. Brown, Albert Einstein College of Medicine, USA
Short Talk: PAR-CLIP Analysis of the Alphavirus Capsid Protein Demonstrates Unique Recognition of the Genomic RNA

Tuesday, June 11 | 11:30AM - 11:45AM
European Virus Archive
Room: INEC Main Auditorium

Speaker 1 of 1
Christine MA Prat, European Virus Archive, France

Tuesday, June 11 | 11:30AM - 5:00PM
On Own for Lunch


Tuesday, June 11 | 11:30AM - 1:00PM
Poster Setup
Room: 1st Floor INEC


Tuesday, June 11 | 1:00PM - 10:00PM
Poster Viewing
Room: 1st Floor INEC


Tuesday, June 11 | 2:00PM - 4:30PM
Workshop 2
Room: INEC Main Auditorium

Speaker 1 of 12
* Anna K. Overby, Umeå University, Sweden

Tuesday, June 11 | 2:00PM - 4:30PM
Workshop 2
Room: INEC Main Auditorium

Speaker 2 of 12
* Eric Jan, University of British Columbia, Canada

Tuesday, June 11 | 2:00PM - 4:30PM
Workshop 2
Room: INEC Main Auditorium

Speaker 3 of 12
Alexander E. Gorbalenya, Leiden University Medical Center, Netherlands
Domain Linkage in the Largest Expansion of RNA Virus Genomes

Tuesday, June 11 | 2:00PM - 4:30PM
Workshop 2
Room: INEC Main Auditorium

Speaker 4 of 12
Benjamin Götte, Karolinska Institutet, Sweden
Separate Domains of G3BP Promote Efficient Clustering of Alphavirus Replication Complexes and Recruitment of the Translation Initiation Machinery

Tuesday, June 11 | 2:00PM - 4:30PM
Workshop 2
Room: INEC Main Auditorium

Speaker 5 of 12
Jelke J. Fros, Wageningen University, Netherlands
Newly Discovered Antiviral Pathways Control RNA Virus Replication and Drive Virus Evolution

Tuesday, June 11 | 2:00PM - 4:30PM
Workshop 2
Room: INEC Main Auditorium

Speaker 6 of 12
Holly Ramage, University of Pennsylvania, USA
Using Proteomics Tools to Discover New Mechanisms in Flaviviral Infection

Tuesday, June 11 | 2:00PM - 4:30PM
Workshop 2
Room: INEC Main Auditorium

Speaker 7 of 12
Montserrat Barcena, Leiden University Medical Center, Netherlands
The Origin of Enterovirus Replication Organelles Established by Whole-Cell Electron Microscopy

Tuesday, June 11 | 2:00PM - 4:30PM
Workshop 2
Room: INEC Main Auditorium

Speaker 8 of 12
Thomas Morrison, University of Colorado School of Medicine, USA
Scavenger Receptors on Liver Phagocytes Mediate Clearance of Blood-Borne Alphaviruses through Recognition of Modified Lysine Residues in Viral Glycoproteins

Tuesday, June 11 | 2:00PM - 4:30PM
Workshop 2
Room: INEC Main Auditorium

Speaker 9 of 12
Colin Xinru Cheng, Duke-NUS Medical School, Singapore
Impact of Nuclear vs Cytoplasmic Localisation of Dengue Virus NS5

Tuesday, June 11 | 2:00PM - 4:30PM
Workshop 2
Room: INEC Main Auditorium

Speaker 10 of 12
Jing Jin, Vitalant Research Institute, USA
Antigen-Crosslinking Dependent Antiviral Mechanisms

Tuesday, June 11 | 2:00PM - 4:30PM
Workshop 2
Room: INEC Main Auditorium

Speaker 11 of 12
Lisa Chon Lindesmith, University of North Carolina at Chapel Hill, USA
Molecular Delineation of the Serum Antibody Repertoire Reveals Structural Mechanisms for Broad Antibody Responses following Human Norovirus Vaccination

Tuesday, June 11 | 2:00PM - 4:30PM
Workshop 2
Room: INEC Main Auditorium

Speaker 12 of 12
Alexander A. Khromykh, University of Queensland, Australia
Determinants of Zika Virus Host Tropism Uncovered by Deep Mutational Scanning

Tuesday, June 11 | 4:30PM - 5:00PM
Coffee Available
Room: INEC Foyer


Tuesday, June 11 | 5:00PM - 7:00PM
Virus Replication, Evolution and Virus-Cell Interactions
Room: INEC Main Auditorium

Speaker 1 of 7
* Jason Mackenzie, University of Melbourne, Australia

Tuesday, June 11 | 5:00PM - 7:00PM
Virus Replication, Evolution and Virus-Cell Interactions
Room: INEC Main Auditorium

Speaker 2 of 7
* Volker Lohmann, Heidelberg University, Germany

Tuesday, June 11 | 5:00PM - 7:00PM
Virus Replication, Evolution and Virus-Cell Interactions
Room: INEC Main Auditorium

Speaker 3 of 7
Frank van Kuppeveld, Utrecht University, Netherlands
A Novel Viral Mechanism to Prevent Translation Inhibition and Activation of the Integrated Stress Response

Tuesday, June 11 | 5:00PM - 7:00PM
Virus Replication, Evolution and Virus-Cell Interactions
Room: INEC Main Auditorium

Speaker 4 of 7
Peter D. Nagy, University of Kentucky, USA
Viral and Host Players in Tombusvirus Replication

Tuesday, June 11 | 5:00PM - 7:00PM
Virus Replication, Evolution and Virus-Cell Interactions
Room: INEC Main Auditorium

Speaker 5 of 7
Raul Andino, University of California, San Francisco, USA
Viral Generated Inter-Organelle Contacts Redirect Lipid Flux for Genome Replication

Tuesday, June 11 | 5:00PM - 7:00PM
Virus Replication, Evolution and Virus-Cell Interactions
Room: INEC Main Auditorium

Speaker 6 of 7
Karim Majzoub, Stanford University, USA
Short Talk: An RNA-Centric Dissection of Host Complexes Controlling Flavivirus Infection

Tuesday, June 11 | 5:00PM - 7:00PM
Virus Replication, Evolution and Virus-Cell Interactions
Room: INEC Main Auditorium

Speaker 7 of 7
Robert N. Kirchdoerfer, The Scripps Research Institute, USA
Short Talk: Structure of the SARS-CoV NSP12 Polymerase Bound to NSP7 and NSP8 Co-Factors

Tuesday, June 11 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: INEC Foyer
No registration fees are used to fund alcohol served at this function.

Tuesday, June 11 | 7:30PM - 10:00PM
Poster Session 2
Room: 1st Floor INEC


Wednesday, June 12 | 8:30AM - 11:30AM
Immunology of Infection and Viral Evasion Mechanisms
Room: INEC Main Auditorium

Speaker 1 of 8
* Susan C. Baker, Loyola University Chicago, USA

Wednesday, June 12 | 8:30AM - 11:30AM
Immunology of Infection and Viral Evasion Mechanisms
Room: INEC Main Auditorium

Speaker 2 of 8
Michaela U. Gack, University of Chicago, USA
Intracellular Virus Sensing Pathways and Viral Evasion Strategies

Wednesday, June 12 | 8:30AM - 11:30AM
Immunology of Infection and Viral Evasion Mechanisms
Room: INEC Main Auditorium

Speaker 3 of 8
Marlene Dreux, INSERM U1111 International Center for Research in Infectionology (CIRI) Lyon, France
Plasmacytoid Dendritic Cells and Infected Cells form an Interferogenic Synapse Required for Antiviral Responses

Wednesday, June 12 | 8:30AM - 11:30AM
Immunology of Infection and Viral Evasion Mechanisms
Room: INEC Main Auditorium


Coffee Break

Wednesday, June 12 | 8:30AM - 11:30AM
Immunology of Infection and Viral Evasion Mechanisms
Room: INEC Main Auditorium

Speaker 5 of 8
Sujan Shresta, La Jolla Institute for Immunology, USA
Antigenic Cross-Reactivity between Dengue and Zika Viruses: Time for a Pan-Flavivirus Vaccine?

Wednesday, June 12 | 8:30AM - 11:30AM
Immunology of Infection and Viral Evasion Mechanisms
Room: INEC Main Auditorium

Speaker 6 of 8
Stephanie Karst, University of Florida, USA
The Influence of the Intestinal Microbiota on Norovirus Pathogenesis

Wednesday, June 12 | 8:30AM - 11:30AM
Immunology of Infection and Viral Evasion Mechanisms
Room: INEC Main Auditorium

Speaker 7 of 8
Jason Mackenzie, University of Melbourne, Australia
Short Talk: Norovirus Infection Arrests Host Cell Translation Uncoupled from the Stress Granule-PKR-eIF2a Axis

Wednesday, June 12 | 8:30AM - 11:30AM
Immunology of Infection and Viral Evasion Mechanisms
Room: INEC Main Auditorium

Speaker 8 of 8
* Ana Fernandez-Sesma, Icahn School of Medicine at Mount Sinai, USA
Short Talk: Inhibition of Human Innate Immune Responses by Chikungunya Virus (CHIKV)

Wednesday, June 12 | 11:30AM - 12:00PM
The Virus Pathogen Resource (ViPR)
Room: INEC Main Auditorium
ViPR is a freely-available NIH/NIAID-funded online Bioinformatics Resource Center supporting viral pathogen research. ViPR provides access to sequence records, immune epitopes and 3D protein structures, and unique annotations generated from ViPR bioinformatics pipelines including genotype/subtype assignments, mature peptide predications and sequence feature variant types. ViPR also provides analysis tools and supports many analysis workflows, including metadata/subtype-based genome and mature peptide sequence search, phylogenetic analysis with metadata/subtype visualization, sequence variation analysis using various approaches, and more. This workshop will provide a live demonstration of ViPR's major search and analysis capabilities through a Zika virus use case.
Speaker 1 of 1
Yun Zhang, J. Craig Venter Institute, USA

Wednesday, June 12 | 11:30AM - 5:00PM
On Own for Lunch


Wednesday, June 12 | 11:30AM - 1:00PM
Poster Setup
Room: 1st Floor INEC


Wednesday, June 12 | 1:00PM - 10:00PM
Poster Viewing
Room: 1st Floor INEC


Wednesday, June 12 | 2:00PM - 4:30PM
Workshop 3
Room: INEC Main Auditorium

Speaker 1 of 11
* Vineet D. Menachery, University of Texas Medical Branch, USA

Wednesday, June 12 | 2:00PM - 4:30PM
Workshop 3
Room: INEC Main Auditorium

Speaker 2 of 11
* Gregory D. Ebel, Colorado State University, USA

Wednesday, June 12 | 2:00PM - 4:30PM
Workshop 3
Room: INEC Main Auditorium

Speaker 3 of 11
Mayra Alejandra Diosa-Toro, Duke-NUS Medical School, Singapore
Identification and Characterization of Mosquito RNA-Binding Proteins that Regulate Dengue Virus Infection

Wednesday, June 12 | 2:00PM - 4:30PM
Workshop 3
Room: INEC Main Auditorium

Speaker 4 of 11
Christopher J. Neufeldt, University of Heidelberg, Germany
ER-Shaping Atlastin Proteins Differentially Contribute to Flavivirus Replication and Assembly

Wednesday, June 12 | 2:00PM - 4:30PM
Workshop 3
Room: INEC Main Auditorium

Speaker 5 of 11
Rushika Perera, Colorado State University, USA
Host Metabolism: Friend or Foe in Flavivirus Biogenesis and Disease

Wednesday, June 12 | 2:00PM - 4:30PM
Workshop 3
Room: INEC Main Auditorium

Speaker 6 of 11
Jana Van Dycke, KU Leuven – Rega Institute, Belgium
Zebrafish Larvae as an in vivo Replication Model of Human Norovirus

Wednesday, June 12 | 2:00PM - 4:30PM
Workshop 3
Room: INEC Main Auditorium

Speaker 7 of 11
Marjolein Kikkert, Leiden University Medical Center, Netherlands
The Deubiquitinating Activity of Middle East Respiratory Syndrome Coronavirus Papain-Like Protease Contributes to Innate Immune Evasion and Enhances Viral Virulence

Wednesday, June 12 | 2:00PM - 4:30PM
Workshop 3
Room: INEC Main Auditorium

Speaker 8 of 11
Kizzmekia S. Corbett, NIAID, National Institutes of Health, USA
Prefusion MERS Coronavirus Spike Trimer Vaccination Elicits Protective Antibodies Targeting Epitopes Outside of Receptor Binding Domain

Wednesday, June 12 | 2:00PM - 4:30PM
Workshop 3
Room: INEC Main Auditorium

Speaker 9 of 11
Lara J. Herrero, Griffith University, Australia
Alphaviruses and Chondrocytes: New Insights into the Mechanisms of Viral Arthritic Disease

Wednesday, June 12 | 2:00PM - 4:30PM
Workshop 3
Room: INEC Main Auditorium

Speaker 10 of 11
Maria Isabel Giraldo, University of Texas Medical Branch, USA
Flavivirus Envelope Protein Ubiquitination Drives Virus Entry and Pathogenesis

Wednesday, June 12 | 2:00PM - 4:30PM
Workshop 3
Room: INEC Main Auditorium

Speaker 11 of 11
Gorben Pijlman, Wageningen University, Netherlands
Subgenomic Flavivirus RNA Binds the Antiviral Mosquito DEAD/H-Box Helicase ME31B and Determines Zika Virus Transmission by Aedes Aegypti

Wednesday, June 12 | 4:30PM - 5:00PM
Coffee Available
Room: INEC Foyer


Wednesday, June 12 | 5:00PM - 7:00PM
Vaccines, Therapeutic Antibodies and Antiviral Drugs
Room: INEC Main Auditorium

Speaker 1 of 6
* Stanley Perlman, University of Iowa, USA

Wednesday, June 12 | 5:00PM - 7:00PM
Vaccines, Therapeutic Antibodies and Antiviral Drugs
Room: INEC Main Auditorium

Speaker 2 of 6
Davide Corti, Humabs BioMed SA, Switzerland
Passive Antibody Therapies Against Endemic, Emerging and Re-Emerging Infectious Diseases

Wednesday, June 12 | 5:00PM - 7:00PM
Vaccines, Therapeutic Antibodies and Antiviral Drugs
Room: INEC Main Auditorium

Speaker 3 of 6
Alexander Ploss, Princeton University, USA
Model Systems to Assess Vaccine-Induced Immune Responses in vivo

Wednesday, June 12 | 5:00PM - 7:00PM
Vaccines, Therapeutic Antibodies and Antiviral Drugs
Room: INEC Main Auditorium

Speaker 4 of 6
Bali Pulendran, Stanford University School of Medicine, USA
Probing the Immune Response to Vaccination with Systems Based Approaches

Wednesday, June 12 | 5:00PM - 7:00PM
Vaccines, Therapeutic Antibodies and Antiviral Drugs
Room: INEC Main Auditorium

Speaker 5 of 6
* Priscilla L. Yang, Harvard Medical School, USA
Short Talk: Targeted Protein Degradation as an Antiviral Strategy

Wednesday, June 12 | 5:00PM - 7:00PM
Vaccines, Therapeutic Antibodies and Antiviral Drugs
Room: INEC Main Auditorium

Speaker 6 of 6
Lucia Carrau, Institut Pasteur, France
Short Talk: Chikungunya Virus Vaccine Candidates with Decreased Mutational Robustness are Attenuated in vivo and have Compromised Transmissibility

Wednesday, June 12 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: INEC Foyer
No registration fees are used to fund alcohol served at this function.

Wednesday, June 12 | 7:30PM - 10:00PM
Poster Session 3
Room: 1st Floor INEC


Thursday, June 13 | 8:00AM - 8:30AM
Poster Setup
Room: 1st Floor INEC


Thursday, June 13 | 8:30AM - 5:00PM
Poster Viewing
Room: 1st Floor INEC


Thursday, June 13 | 8:30AM - 11:30AM
Virus Transmission, Tropism and Pathogenesis
Room: INEC Main Auditorium

Speaker 1 of 8
* Ricardo Rajsbaum, University of Texas Medical Branch, USA

Thursday, June 13 | 8:30AM - 11:30AM
Virus Transmission, Tropism and Pathogenesis
Room: INEC Main Auditorium

Speaker 2 of 8
Carolyn B. Coyne, University of Pittsburgh, USA
The Role of the Neonatal Fc Receptor in Echovirus Entry and Pathogenesis.

Thursday, June 13 | 8:30AM - 11:30AM
Virus Transmission, Tropism and Pathogenesis
Room: INEC Main Auditorium

Speaker 3 of 8
Christian Drosten, Charité - Universitätsmedizin Berlin, Germany
Ecology, Inter-species Transmission, and Pathogenic Potential of Emerging Coronaviruses

Thursday, June 13 | 8:30AM - 11:30AM
Virus Transmission, Tropism and Pathogenesis
Room: INEC Main Auditorium


Coffee Break

Thursday, June 13 | 8:30AM - 11:30AM
Virus Transmission, Tropism and Pathogenesis
Room: INEC Main Auditorium

Speaker 5 of 8
Diane E. Griffin, Johns Hopkins Bloomberg School of Public Health, USA
Role of Alphavirus nsP3 in Replication and Neurovirulence

Thursday, June 13 | 8:30AM - 11:30AM
Virus Transmission, Tropism and Pathogenesis
Room: INEC Main Auditorium

Speaker 6 of 8
Xiang-Jin Meng, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, USA
Hepatitis E Virus: The Ever-Expanding Host Range and Cross-Species Infection

Thursday, June 13 | 8:30AM - 11:30AM
Virus Transmission, Tropism and Pathogenesis
Room: INEC Main Auditorium

Speaker 7 of 8
* Eva Harris, Division of Infectious Diseases and Vaccinology, School of Public Health, USA
Short Talk: Molecular Mechanisms and Determinants of Flavivirus NS1-Induced Endothelial Permeability, Vascular Leak, and
Virus Dissemination


Thursday, June 13 | 8:30AM - 11:30AM
Virus Transmission, Tropism and Pathogenesis
Room: INEC Main Auditorium

Speaker 8 of 8
Stacey Lynne Schultz-Cherry, St. Jude Children's Research Hospital, USA
Short Talk: Astrovirus Capsid is a Novel Viral Enterotoxin

Thursday, June 13 | 11:30AM - 12:30PM
Lunch
Room: INEC Foyer


Thursday, June 13 | 12:00PM - 2:30PM
Poster Session 4
Room: 1st Floor INEC


Thursday, June 13 | 4:30PM - 5:00PM
Coffee Available
Room: INEC Foyer


Thursday, June 13 | 5:00PM - 6:45PM
Invertebrate Viruses and their Vectors
Room: INEC Main Auditorium

Speaker 1 of 6
* Gorben Pijlman, Wageningen University, Netherlands

Thursday, June 13 | 5:00PM - 6:45PM
Invertebrate Viruses and their Vectors
Room: INEC Main Auditorium

Speaker 2 of 6
* Laura D. Kramer, Wadsworth Center, New York State Department of Health; SUNY Albany, USA

Thursday, June 13 | 5:00PM - 6:45PM
Invertebrate Viruses and their Vectors
Room: INEC Main Auditorium

Speaker 3 of 6
Erol Fikrig, Yale University School of Medicine, USA
Aedes aegypti AgBR1 Influences Early Zika Virus Infection

Thursday, June 13 | 5:00PM - 6:45PM
Invertebrate Viruses and their Vectors
Room: INEC Main Auditorium

Speaker 4 of 6
Maria-Carla Saleh, Institut Pasteur, France
Principal Components of Innate Immunity Pathways Constrain Viral Evolution

Thursday, June 13 | 5:00PM - 6:45PM
Invertebrate Viruses and their Vectors
Room: INEC Main Auditorium

Speaker 5 of 6
Ronald P. van Rij, Radboud University Medical Center, Netherlands
Biogenesis and Functions of Virus and Host-Derived piRNAs in Vector Mosquitoes

Thursday, June 13 | 5:00PM - 6:45PM
Invertebrate Viruses and their Vectors
Room: INEC Main Auditorium

Speaker 6 of 6
Diego Alvarez, Universidad Nacional de San Martín, Argentina
Short Talk: RNA Recombination Allows Chikungunya Virus to Overcome Barriers Imposed during Mosquito Transmission

Thursday, June 13 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: INEC Main Auditorium


Thursday, June 13 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: INEC Foyer
No registration fees are used to fund alcohol served at this function.

Thursday, June 13 | 8:00PM - 11:00PM
Entertainment
Room: INEC Foyer
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, June 13 | 8:00PM - 11:00PM
Cash Bar
Room: INEC Foyer


Friday, June 14 | 10:24AM - 10:24AM
Departure


*Session Chair.