Web Desc
Innate Immune Receptors: Roles in Immunology and Beyond
Organizer(s): Jenny P.Y. Ting, Shie-Liang Edmond Hsieh, Fu-Tong Liu, Michael Gale, Jr. and Siamon Gordon
Date: March 10 - 14, 2019
Location: Humanities/Social Sciences Building of Academia Sinica, Taipei, Taiwan
Developed in collaboration with Academia Sinica

Sponsored by BioLegend, Inc. and Genentech, Inc.
Summary of Meeting:
Innate immune receptors include a plethora of membrane-associated proteins as well as intracellular receptors that directly bind or sense the presence of pathogen-associated molecular patterns (PAMPs). The importance of innate immune receptors was first appreciated in infectious diseases and autoinflammatory disorders, but it is now clear that their roles extend beyond innate immunology. The crucial roles of these receptors in many clinically relevant fields, and their newly documented role in non-immune cells, underscore their importance in biologic processes and diseases. This conference will address the ligands and signaling mechanisms of a diverse set of innate immune receptors as well as the profound impacts of innate immune receptors on the microbiome, which in turn has impacts on multiple organ systems. The program includes discussion of the intrinsic functions of innate immune receptors within adaptive immune cells, non-immune cells such as epithelial and endothelial cells, and their roles in cancer and stem cells. The pleitrophic effects of this important receptor class have far-reaching consequences for critical biological processes such as cancer cell death and signaling, DNA damage, stress response, stem cell proliferation/differentiation, vaccine adjuvanticity, age-related dementia, metabolic disorders and microbiome balance. By the nature of the topic, this conference brings together an interdisciplinary group of investigators to catalyze cross-fertilization of ideas and stimulate important medical advances.
Scholarship Deadline: November 27 2018
Discounted Abstract Deadline: November 27 2018
Abstract Deadline: December 11 2018
Discounted Registration Deadline: January 17 2019
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

Academia Sinica
BioLegend, Inc.Genentech, Inc.
We gratefully acknowledge additional support from these exhibitors at this conference:
BD BiosciencesFluidigmInvivoGen
We gratefully acknowledge additional support for this conference from:
AdipoGen Life Sciences
China Medical University

Chinese Society of Immunology
eLifeMinistry of Science and TechnologyNational Cheng Kung University College of Medicine
National Health Research Institutes
National Taiwan University College of Medicine
National Yang-Ming University

Taiwan Rheumatology Association
Tekon Scientific CorporationThe Bureau of Foreign Trade, MOEA
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Dynavax Technologies Corporation
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI142987-01
Funding for this conference was made possible (in part) by 1R13AI142987-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, March 10 | 4:00PM - 8:00PM
Arrival and Registration
Room: Courtyard Marriott


Sunday, March 10 | 6:00PM - 8:00PM
Welcome Mixer
Room: The Lounge, Courtyard Marriott
No registration fees are used to fund alcohol served at this function.

Monday, March 11 | 9:00AM - 9:50AM
Welcome and Keynote Address
Room: International Conference Hall

Speaker 1 of 2
* Siamon Gordon, Chang Gung University / University of Oxford, UK

Monday, March 11 | 9:00AM - 9:50AM
Welcome and Keynote Address
Room: International Conference Hall

Speaker 2 of 2
Vishva M. Dixit, Genentech, Inc., USA
Interplay Between Regulators of Apoptosis and Necroptosis

Monday, March 11 | 9:50AM - 12:30PM
Innate Immune Receptors and Nucleic Acid Sensing
Room: International Conference Hall

Speaker 1 of 7
* Michael S. Diamond, Washington University School of Medicine, USA

Monday, March 11 | 9:50AM - 12:30PM
Innate Immune Receptors and Nucleic Acid Sensing
Room: International Conference Hall

Speaker 2 of 7
Michael Gale, Jr., University of Washington, USA
Programming Immunity against Virus Infection

Monday, March 11 | 9:50AM - 12:30PM
Innate Immune Receptors and Nucleic Acid Sensing
Room: International Conference Hall


Coffee Break

Monday, March 11 | 9:50AM - 12:30PM
Innate Immune Receptors and Nucleic Acid Sensing
Room: International Conference Hall

Speaker 4 of 7
Zhijian 'James' Chen, University of Texas Southwestern Medical Center, USA
DNA Sensing by cGAS: Chemistry, Biology and Application

Monday, March 11 | 9:50AM - 12:30PM
Innate Immune Receptors and Nucleic Acid Sensing
Room: International Conference Hall

Speaker 5 of 7
Jenny P.Y. Ting, University of North Carolina at Chapel Hill, USA
Nucleic Acid Sensing and Immune Regulation

Monday, March 11 | 9:50AM - 12:30PM
Innate Immune Receptors and Nucleic Acid Sensing
Room: International Conference Hall

Speaker 6 of 7
Sun Hur, Harvard Medical School, USA
RNA Sensing: Structure and Disease Relevance

Monday, March 11 | 9:50AM - 12:30PM
Innate Immune Receptors and Nucleic Acid Sensing
Room: International Conference Hall

Speaker 7 of 7
Layal Liverpool, University of Oxford, UK
Short Talk: Z-Nucleic Acids in Virus-Host Interactions

Monday, March 11 | 10:30AM - 12:30PM
Poster Setup
Room: South Wing


Monday, March 11 | 12:30PM - 1:30PM
Lunch
Room: Back Corridor


Monday, March 11 | 12:45PM - 3:00PM
Poster Session 1
Room: South Wing


Monday, March 11 | 3:00PM - 5:00PM
Workshop 1: Innate Immune Receptors: Regulation and Infectio
n
Room: International Conference Hall

Speaker 1 of 10
* Ming-Daw Tsai, Academia Sinica, Taiwan

Monday, March 11 | 3:00PM - 5:00PM
Workshop 1: Innate Immune Receptors: Regulation and Infectio
n
Room: International Conference Hall

Speaker 2 of 10
* Amal Amer, Ohio State University, USA

Monday, March 11 | 3:00PM - 5:00PM
Workshop 1: Innate Immune Receptors: Regulation and Infectio
n
Room: International Conference Hall

Speaker 3 of 10
Baptiste Guey, École Polytechnique Fédérale de Lausanne, Switzerland
Chromatin Mechanics Regulate cGAS Activity against Self-DNA

Monday, March 11 | 3:00PM - 5:00PM
Workshop 1: Innate Immune Receptors: Regulation and Infectio
n
Room: International Conference Hall

Speaker 4 of 10
Cynthia Korin Bullen, Johns Hopkins School of Medicine, USA
Mycobacterium tuberculosis Engages the MDA5 RNA Sensing Pathway to Subvert Innate Immune Responses and Facilitate its Survival within Macrophages

Monday, March 11 | 3:00PM - 5:00PM
Workshop 1: Innate Immune Receptors: Regulation and Infectio
n
Room: International Conference Hall

Speaker 5 of 10
Szu-Ting Chen, National Yang Ming University, Taiwan
NLRP12 Regulates TRIM25 Activation and Ubiquitination of RIG-I

Monday, March 11 | 3:00PM - 5:00PM
Workshop 1: Innate Immune Receptors: Regulation and Infectio
n
Room: International Conference Hall

Speaker 6 of 10
Yi-Shan Chien, National Taiwan University, Taiwan
A Novel DEAD Box RNA Helicase Negatively Regulates NLRP3 Inflammasome Activation

Monday, March 11 | 3:00PM - 5:00PM
Workshop 1: Innate Immune Receptors: Regulation and Infectio
n
Room: International Conference Hall

Speaker 7 of 10
Rei-Lin Kuo, Chang Gung University, Taiwan
Regulation of RIG-I-Initiated IFN-beta Transcription by the N Terminus-Truncated NS1 Protein of Influenza A Virus

Monday, March 11 | 3:00PM - 5:00PM
Workshop 1: Innate Immune Receptors: Regulation and Infectio
n
Room: International Conference Hall

Speaker 8 of 10
MH Tsai, National Taiwan University, Taiwan
STAT3 Cooperates with Phospholipid Scramblase 2 to Suppress Type I Interferon-Induced Antiviral and Inflammatory Response

Monday, March 11 | 3:00PM - 5:00PM
Workshop 1: Innate Immune Receptors: Regulation and Infectio
n
Room: International Conference Hall

Speaker 9 of 10
Bin Wu, Nanyang Technological University, Singapore
Structural Basis of RIP2 Activation and Signaling

Monday, March 11 | 3:00PM - 5:00PM
Workshop 1: Innate Immune Receptors: Regulation and Infectio
n
Room: International Conference Hall

Speaker 10 of 10
Na Dong, China Agricultural University, China
The N-end Rule E3 Ligase UBR2 Mediates NLRP1B Inflammasome Activation by Anthrax Lethal Toxin

Monday, March 11 | 5:00PM - 5:30PM
Coffee Available
Room: Foyer


Monday, March 11 | 5:30PM - 7:30PM
Innate Immune Receptors in Cell Death
Room: International Conference Hall

Speaker 1 of 6
* Michael Gale, Jr., University of Washington, USA

Monday, March 11 | 5:30PM - 7:30PM
Innate Immune Receptors in Cell Death
Room: International Conference Hall

Speaker 2 of 6
Feng Shao, National Institute of Biological Sciences, China
Innate Sensing of Cytosolic LPS: Pyroptosis and Beyond

Monday, March 11 | 5:30PM - 7:30PM
Innate Immune Receptors in Cell Death
Room: International Conference Hall

Speaker 3 of 6
Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA
Molecular Targets for the Treatment of Inflammatory and Infectious Diseases

Monday, March 11 | 5:30PM - 7:30PM
Innate Immune Receptors in Cell Death
Room: International Conference Hall

Speaker 4 of 6
Edward A. Miao, University of North Carolina at Chapel Hill, USA
Infectious Models Reveal a Unique Role for Caspase-7 after Cytotoxic Lymphocyte Attack

Monday, March 11 | 5:30PM - 7:30PM
Innate Immune Receptors in Cell Death
Room: International Conference Hall

Speaker 5 of 6
Jye-Lin Hsu, China Medical University, Taiwan
Short Talk: Glutathione Peroxidase 8 Negatively Regulates Caspase-4/11 to Protect against Colitis by Restraining NLRP3-Inflammasome Activation

Monday, March 11 | 5:30PM - 7:30PM
Innate Immune Receptors in Cell Death
Room: International Conference Hall

Speaker 6 of 6
Jia Yao, Emory University, USA
Short Talk: p38MAPK Senses the Integrity of Endosomal Compartments through Regulating Necrotic Death

Monday, March 11 | 7:30PM - 7:30PM
On Own for Dinner


Tuesday, March 12 | 9:00AM - 12:00PM
Innate Immune Receptors and Diseases
Room: International Conference Hall

Speaker 1 of 9
* Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA

Tuesday, March 12 | 9:00AM - 12:00PM
Innate Immune Receptors and Diseases
Room: International Conference Hall

Speaker 2 of 9
Akira Shizuo, Osaka University, Japan
The Control of Inflammatory and Immune Responses by the Endoribonuclease Regnase-1

Tuesday, March 12 | 9:00AM - 12:00PM
Innate Immune Receptors and Diseases
Room: International Conference Hall

Speaker 3 of 9
Amal Amer, Ohio State University, USA
The Role of Caspase-11 in Sickness and in Health

Tuesday, March 12 | 9:00AM - 12:00PM
Innate Immune Receptors and Diseases
Room: International Conference Hall


Coffee Break

Tuesday, March 12 | 9:00AM - 12:00PM
Innate Immune Receptors and Diseases
Room: International Conference Hall

Speaker 5 of 9
Fu-Tong Liu, Academia Sinica, Taiwan
Galectins and Innate Immunity

Tuesday, March 12 | 9:00AM - 12:00PM
Innate Immune Receptors and Diseases
Room: International Conference Hall

Speaker 6 of 9
Carla V. Rothlin, Yale University, USA
TAM Receptors and the Regulation of Macrophage Polarization

Tuesday, March 12 | 9:00AM - 12:00PM
Innate Immune Receptors and Diseases
Room: International Conference Hall

Speaker 7 of 9
Shu-Hsia Chen, Methodist Research Institute, USA
Short Talk: Blocking Immunoinhibitory Receptor Reprograms Tumor-Associated Myeloid Cells and Promotes Antitumor Immunity

Tuesday, March 12 | 9:00AM - 12:00PM
Innate Immune Receptors and Diseases
Room: International Conference Hall

Speaker 8 of 9
Pei-Yu Wu, Academica Sinica, Taiwan
Short Talk: TIFA-NF-?B Axis Skews Inflammatory Microenvironment to Confer Sorafenib-Resistant Niche for Recurrence of Hepatocellular Carcinoma

Tuesday, March 12 | 9:00AM - 12:00PM
Innate Immune Receptors and Diseases
Room: International Conference Hall

Speaker 9 of 9
Victor R. DeFilippis, Oregon Health & Science University, USA
Short Talk: A Novel Small Molecule Inducer of cGAS Activity Exhibits Multiple Therapeutically Useful Effects

Tuesday, March 12 | 10:30AM - 12:30PM
Poster Setup
Room: South Wing


Tuesday, March 12 | 12:00PM - 1:00PM
Lunch
Room: Back Corridor


Tuesday, March 12 | 12:45PM - 3:00PM
Poster Session 2
Room: South Wing


Tuesday, March 12 | 3:00PM - 5:00PM
Workshop 2: Innate Immune Receptors: Inflammation, Vaccines
and Therapeutics
Room: International Conference Hall

Speaker 1 of 10
* Wan Wan Lin, National Taiwan University, Taiwan

Tuesday, March 12 | 3:00PM - 5:00PM
Workshop 2: Innate Immune Receptors: Inflammation, Vaccines
and Therapeutics
Room: International Conference Hall

Speaker 2 of 10
* Shu-Hsia Chen, Methodist Research Institute, USA

Tuesday, March 12 | 3:00PM - 5:00PM
Workshop 2: Innate Immune Receptors: Inflammation, Vaccines
and Therapeutics
Room: International Conference Hall

Speaker 3 of 10
Fu Hsin, National Taiwan University, Taiwan
Hepatic Suppression of STING-Mediated Type I Interferon Induction by Hepsin

Tuesday, March 12 | 3:00PM - 5:00PM
Workshop 2: Innate Immune Receptors: Inflammation, Vaccines
and Therapeutics
Room: International Conference Hall

Speaker 4 of 10
Eunju Lee, Yonsei University, South Korea
Role of Microglial NLRP3 Inflammasome in the Dopaminergic Neurodegeneration of Parkinson's Disease

Tuesday, March 12 | 3:00PM - 5:00PM
Workshop 2: Innate Immune Receptors: Inflammation, Vaccines
and Therapeutics
Room: International Conference Hall

Speaker 5 of 10
Subhash Mehto, Institute of Life Sciences, India
IRGM Limits NLRP3 Inflammasome Activation by Impeding its Assembly and by Mediating its Selective Autophagy

Tuesday, March 12 | 3:00PM - 5:00PM
Workshop 2: Innate Immune Receptors: Inflammation, Vaccines
and Therapeutics
Room: International Conference Hall

Speaker 6 of 10
Hsi-Hsien Lin, Chang Gung University, Taiwan
The Role of Macrophage Adhesion-GPCR EMR2/ADGRE2 in the Activation of NLRP3 Inflammasome

Tuesday, March 12 | 3:00PM - 5:00PM
Workshop 2: Innate Immune Receptors: Inflammation, Vaccines
and Therapeutics
Room: International Conference Hall

Speaker 7 of 10
Jia Tong Loh, Bioprocessing Technology Institute, Singapore
Dok3 Recruits PP1 to Attenuate Card9 Signaling in Neutrophils during Host Innate Anti-Fungal Immunity

Tuesday, March 12 | 3:00PM - 5:00PM
Workshop 2: Innate Immune Receptors: Inflammation, Vaccines
and Therapeutics
Room: International Conference Hall

Speaker 8 of 10
Kuan-Ting Liu, Chang Gung University, Taiwan
Role of Gender on Disease Severity of Enterovirus A 71 Infection

Tuesday, March 12 | 3:00PM - 5:00PM
Workshop 2: Innate Immune Receptors: Inflammation, Vaccines
and Therapeutics
Room: International Conference Hall

Speaker 9 of 10
Suktika Chandra, Institute of Molecular Biology, Taiwan
Deciphering the Innate Immune Response that Differentially Restricts Vaccinia Virus Having Different Entry Pathways

Tuesday, March 12 | 3:00PM - 5:00PM
Workshop 2: Innate Immune Receptors: Inflammation, Vaccines
and Therapeutics
Room: International Conference Hall

Speaker 10 of 10
Amy Elizabeth Mawdesley, Newcastle University, UK
Preventing Cobalt-Chromium Wear Particle Mediated TLR4 Activation and Subsequent Inflammatory Response

Tuesday, March 12 | 5:00PM - 5:30PM
Coffee Available
Room: Foyer


Tuesday, March 12 | 5:30PM - 7:30PM
Innate Immunity and Therapeutics
Room: International Conference Hall

Speaker 1 of 6
* Fu-Tong Liu, Academia Sinica, Taiwan

Tuesday, March 12 | 5:30PM - 7:30PM
Innate Immunity and Therapeutics
Room: International Conference Hall

Speaker 2 of 6
Robert L. Coffman, Dynavax Technologies, USA
Harnessing Innate Immunity for Cancer Immunotherapy

Tuesday, March 12 | 5:30PM - 7:30PM
Innate Immunity and Therapeutics
Room: International Conference Hall

Speaker 3 of 6
Mihai G. Netea, Radboud University, Netherlands
Metabolic and Epigenetic Reprogramming in Trained Immunity

Tuesday, March 12 | 5:30PM - 7:30PM
Innate Immunity and Therapeutics
Room: International Conference Hall

Speaker 4 of 6
Glen N. Barber, University of Miami, USA
STING Signaling in Infectious Disease, Inflammation and Cancer

Tuesday, March 12 | 5:30PM - 7:30PM
Innate Immunity and Therapeutics
Room: International Conference Hall

Speaker 5 of 6
Wan Wan Lin, National Taiwan University, Taiwan
Short Talk: Purinergic P2X7 in Inflammation: Regulation of Mitochondrial Dynamics and Lysosomal Biogenesis in Macrophages

Tuesday, March 12 | 5:30PM - 7:30PM
Innate Immunity and Therapeutics
Room: International Conference Hall

Speaker 6 of 6
Marcin T. Kortylewski, Beckman Research Institute, City of Hope, USA
Short Talk: Targeted Delivery of CpG-miR-146a Mimic Oligonucleotides to Reduce NF-?B-driven Pathogenic Inflammation and Myeloid Leukemia Progression

Tuesday, March 12 | 7:30PM - 7:30PM
On Own for Dinner
No registration fees are used to fund alcohol served at this function.

Wednesday, March 13 | 9:00AM - 12:00PM
Innate Immune Receptors in Viral Infection
Room: International Conference Hall

Speaker 1 of 9
* Glen N. Barber, University of Miami, USA

Wednesday, March 13 | 9:00AM - 12:00PM
Innate Immune Receptors in Viral Infection
Room: International Conference Hall

Speaker 2 of 9
Michael S. Diamond, Washington University School of Medicine, USA
The Protective Role of Interferon-? in the Placenta and Female Reproductive Tract during Zika Virus Infection

Wednesday, March 13 | 9:00AM - 12:00PM
Innate Immune Receptors in Viral Infection
Room: International Conference Hall

Speaker 3 of 9
Hao Wu, Harvard Medical School, Boston Children's Hospital, USA
Structures and Functions of GSDM Pores

Wednesday, March 13 | 9:00AM - 12:00PM
Innate Immune Receptors in Viral Infection
Room: International Conference Hall


Coffee Break

Wednesday, March 13 | 9:00AM - 12:00PM
Innate Immune Receptors in Viral Infection
Room: International Conference Hall

Speaker 5 of 9
Shie-Liang Hsieh, Academia Sinica, Taiwan
Lectins are Potential Therapeutic Targets in Acute and Chronic Viral Infections

Wednesday, March 13 | 9:00AM - 12:00PM
Innate Immune Receptors in Viral Infection
Room: International Conference Hall

Speaker 6 of 9
Gabriel Nuñez, University of Michigan, USA
Linking NOD2, the Microbiota and Inflammatory Intestinal Disease

Wednesday, March 13 | 9:00AM - 12:00PM
Innate Immune Receptors in Viral Infection
Room: International Conference Hall

Speaker 7 of 9
Chih-Peng Chang, National Cheng Kung University, Taiwan
Short Talk: Integrin-Linked Kinase Supports Dengue Viral Infection by Antagonizing Interferon Signaling

Wednesday, March 13 | 9:00AM - 12:00PM
Innate Immune Receptors in Viral Infection
Room: International Conference Hall

Speaker 8 of 9
Melissa Stunnenberg, Amsterdam University Medical Centers, Netherlands
Short Talk: RNA Sensor DDX3 Is a Potent Inducer of Antiviral Type I Interferon and Adaptive Immunity

Wednesday, March 13 | 9:00AM - 12:00PM
Innate Immune Receptors in Viral Infection
Room: International Conference Hall

Speaker 9 of 9
Donghai Wang, Duke University Medical Center, USA
Short Talk: Control of Antiviral Innate Immune Response by Protein Geranylgeranylation

Wednesday, March 13 | 10:30AM - 1:00PM
Poster Setup
Room: South Wing


Wednesday, March 13 | 12:00PM - 12:30PM
Box Lunches
Room: Foyer


Wednesday, March 13 | 12:30PM - 1:30PM
Meet the Editors
Room: 1st Conference Room

Speaker 1 of 3
Gaia Trincucci, Journal of Experimental Medicine, USA

Wednesday, March 13 | 12:30PM - 1:30PM
Meet the Editors
Room: 1st Conference Room

Speaker 2 of 3
Zoltan Fehervari, Nature Publishing Group, UK

Wednesday, March 13 | 12:30PM - 1:30PM
Meet the Editors
Room: 1st Conference Room

Speaker 3 of 3
Bruce D. Koppelman, Cell Press, USA

Wednesday, March 13 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Wednesday, March 13 | 5:00PM - 7:00PM
Innate Immunity in Bacterial and Fungal Infection
Room: International Conference Hall

Speaker 1 of 5
* Shie-Liang Hsieh, Academia Sinica, Taiwan

Wednesday, March 13 | 5:00PM - 7:00PM
Innate Immunity in Bacterial and Fungal Infection
Room: International Conference Hall

Speaker 2 of 5
Betty A. Wu-Hsieh, National Taiwan University, Taiwan
Innate Immune Receptors in Antifungal Responses

Wednesday, March 13 | 5:00PM - 7:00PM
Innate Immunity in Bacterial and Fungal Infection
Room: International Conference Hall

Speaker 3 of 5
Alan Sher, NIAID, National Institutes of Health, USA
A Role for Ferroptosis in Pathogen Induced Cell Death and Tissue Necrosis

Wednesday, March 13 | 5:00PM - 7:00PM
Innate Immunity in Bacterial and Fungal Infection
Room: International Conference Hall

Speaker 4 of 5
Robert L. Modlin, University of California, Los Angeles, USA
Antimicrobial T Cells Combat Mycobacterial Infection

Wednesday, March 13 | 5:00PM - 7:00PM
Innate Immunity in Bacterial and Fungal Infection
Room: International Conference Hall

Speaker 5 of 5
Ernest Y. Lee, University of California, Los Angeles, USA
Short Talk: Host Defense Peptides Amplify TLR9-Mediated Inflammation in Autoimmune Diseases by Scaffolding dsDNA into Spatially-Periodic Nanocrystals

Wednesday, March 13 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: South Wing
No registration fees are used to fund alcohol served at this function.

Wednesday, March 13 | 7:45PM - 10:00PM
Poster Session 3
Room: South Wing


Thursday, March 14 | 9:00AM - 12:00PM
Innate Immunity and Diseases
Room: International Conference Hall

Speaker 1 of 8
Douglas Golenbock, University of Massachusetts Medical School, USA
Innate Immune Memory in Falciparum Malaria

Thursday, March 14 | 9:00AM - 12:00PM
Innate Immunity and Diseases
Room: International Conference Hall

Speaker 2 of 8
Cheng-Lun Ku, Chang Gung University, Taiwan
Dissect the Molecular Property of Anti-Interferon-? Autoantibodies in Patients with Mycobacterial Infection

Thursday, March 14 | 9:00AM - 12:00PM
Innate Immunity and Diseases
Room: International Conference Hall


Coffee Break

Thursday, March 14 | 9:00AM - 12:00PM
Innate Immunity and Diseases
Room: International Conference Hall

Speaker 4 of 8
Gregory M. Barton, University of California, Berkeley, USA
TLR

Thursday, March 14 | 9:00AM - 12:00PM
Innate Immunity and Diseases
Room: International Conference Hall

Speaker 5 of 8
* Raphaela Theresia Goldbach-Mansky, NIAID, National Institutes of Health, USA
Genetic Basis of Autoinflammatory Diseases

Thursday, March 14 | 9:00AM - 12:00PM
Innate Immunity and Diseases
Room: International Conference Hall

Speaker 6 of 8
Theresa Li-Yun Chang, Rutgers, New Jersey Medical School, USA
Short Talk: Human IFNe and IFNa Modulate Immune and Anti-HIV Functions through the Differential Involvement of IFNa Receptors

Thursday, March 14 | 9:00AM - 12:00PM
Innate Immunity and Diseases
Room: International Conference Hall

Speaker 7 of 8
Guangxun Meng, Institut Pasteur, China
Short Talk: Gasdermin D Drives the Non-Exosomal Secretion of Insulin Signal Antagonist Galectin-3

Thursday, March 14 | 9:00AM - 12:00PM
Innate Immunity and Diseases
Room: International Conference Hall

Speaker 8 of 8
Kim S. Robinson, Agency for Science, Technology and Research (A*STAR), Singapore
Short Talk: ASC Exists in a “Hyper-Alert” State in Psoriatic Lesional Skin which Drives and Amplifies IL-1 Psoriatic Inflammation

Thursday, March 14 | 12:00PM - 1:30PM
Lunch
Room: Back Corridor


Thursday, March 14 | 1:30PM - 3:30PM
Workshop 3: Innate Immune Receptors: Role in Diseases and th
e Microbiome
Room: International Conference Hall

Speaker 1 of 10
* Betty A. Wu-Hsieh, National Taiwan University, Taiwan

Thursday, March 14 | 1:30PM - 3:30PM
Workshop 3: Innate Immune Receptors: Role in Diseases and th
e Microbiome
Room: International Conference Hall

Speaker 2 of 10
* Carla V. Rothlin, Yale University, USA

Thursday, March 14 | 1:30PM - 3:30PM
Workshop 3: Innate Immune Receptors: Role in Diseases and th
e Microbiome
Room: International Conference Hall

Speaker 3 of 10
Brendan J. Jenkins, Hudson Institute of Medical Research, Australia
Uncovering the Pro-Tumourigenic Role of Innate Immune DNA Sensors in Cancer

Thursday, March 14 | 1:30PM - 3:30PM
Workshop 3: Innate Immune Receptors: Role in Diseases and th
e Microbiome
Room: International Conference Hall

Speaker 4 of 10
Miyu Moriyama, University of Tokyo, Japan
Recognition of Influenza A Virus by DNA Sensors

Thursday, March 14 | 1:30PM - 3:30PM
Workshop 3: Innate Immune Receptors: Role in Diseases and th
e Microbiome
Room: International Conference Hall

Speaker 5 of 10
Meihong Deng, University of Pittsburgh, USA
TLR9 Signaling in Fibroblastic Reticular Cells Controls Peritoneal Immunity in Sepsis

Thursday, March 14 | 1:30PM - 3:30PM
Workshop 3: Innate Immune Receptors: Role in Diseases and th
e Microbiome
Room: International Conference Hall

Speaker 6 of 10
Amanda Gavin, The Scripps Research Institute, USA
PLD3 and PLD4 Are ssDNA Exonucleases that Are Required to Prevent Lethal Primary HLH-Like Disease in Mice

Thursday, March 14 | 1:30PM - 3:30PM
Workshop 3: Innate Immune Receptors: Role in Diseases and th
e Microbiome
Room: International Conference Hall

Speaker 7 of 10
Miao-Hsi Hsieh, National Cheng Kung University, Taiwan
Surfactant Protein D Alleviate Ozone and Cigarette-Induced Lung Inflammation and Emphysema in Murine Model of COPD

Thursday, March 14 | 1:30PM - 3:30PM
Workshop 3: Innate Immune Receptors: Role in Diseases and th
e Microbiome
Room: International Conference Hall

Speaker 8 of 10
Bo Liu, University of California, Berkeley, USA
Unc93b1 Recruits Syntenin-1 to Dampen TLR7 Signaling and Prevent Autoimmunity

Thursday, March 14 | 1:30PM - 3:30PM
Workshop 3: Innate Immune Receptors: Role in Diseases and th
e Microbiome
Room: International Conference Hall

Speaker 9 of 10
Hiroyuki Oshiumi, Kumamoto University, Japan
Circulating miR-451 within Exosomes Regulates Toll-Like Receptor-Mediated Innate Immune Responses

Thursday, March 14 | 1:30PM - 3:30PM
Workshop 3: Innate Immune Receptors: Role in Diseases and th
e Microbiome
Room: International Conference Hall

Speaker 10 of 10
Hai Huang, Ohio State University, USA
Caspase-11 Dependent-Pyroptosis Exacerbates Sterile Liver Inflammation

Thursday, March 14 | 3:30PM - 4:00PM
Coffee Available
Room: Foyer


Thursday, March 14 | 4:00PM - 6:00PM
Innate Immune Receptors and the Microbiome
Room: International Conference Hall

Speaker 1 of 6
* Alan Sher, NIAID, National Institutes of Health, USA

Thursday, March 14 | 4:00PM - 6:00PM
Innate Immune Receptors and the Microbiome
Room: International Conference Hall

Speaker 2 of 6
Cathryn R. Nagler, University of Chicago, USA
Microbiome and Food Allergy

Thursday, March 14 | 4:00PM - 6:00PM
Innate Immune Receptors and the Microbiome
Room: International Conference Hall

Speaker 3 of 6
Yang-Xin Fu, University of Texas Southwestern Medical Center, USA
Tumor Targeting Antibodies to Improve Innate and Adaptive Immunity

Thursday, March 14 | 4:00PM - 6:00PM
Innate Immune Receptors and the Microbiome
Room: International Conference Hall

Speaker 4 of 6
Seth L. Masters, Walter and Eliza Hall Institute, Australia
Innate Immune Activation in ALS

Thursday, March 14 | 4:00PM - 6:00PM
Innate Immune Receptors and the Microbiome
Room: International Conference Hall

Speaker 5 of 6
Ya-Jen Chang, Academia Sinica, Taiwan
Short Talk: The Microbial Metabolite Butyrate Regulates Type 2 Innate Lymphoid Cell-Dependent Airway Hyperreactivity

Thursday, March 14 | 4:00PM - 6:00PM
Innate Immune Receptors and the Microbiome
Room: International Conference Hall

Speaker 6 of 6
Jr-Wen Shui, Academia Sinica, Taiwan
Short Talk: Dual Function of ATF3 in Intestinal Epithelial and Th17 Cells in Maintaining Mucosal Immunity

Thursday, March 14 | 6:00PM - 6:30PM
Meeting Wrap-Up: Outcomes and Future Directions
Room: International Conference Hall

Speaker 1 of 1
* Siamon Gordon, Chang Gung University / University of Oxford, UK

Thursday, March 14 | 6:30PM - 7:30PM
Social Hour with Lite Bites
Room: Back Corridor
No registration fees are used to fund alcohol served at this function.

Thursday, March 14 | 7:30PM - 10:00PM
Entertainment
Room: Back Corridor
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, March 14 | 7:30PM - 10:00PM
Cash Bar
Room: Back Corridor


Friday, March 15 | 10:24AM - 10:24AM
Departure


*Session Chair.