Cancer Metastasis: The Role of Metabolism, Immunity and the Microenvironment

Organizer(s): Erika L. Pearce, Sarah-Maria Fendt, Russell G. Jones and Peter F. Carmeliet

Organized in collaboration with the following organizations - Cancer Research UK and Menarini International Foundation

Sponsored by Autolus Therapeutics

Summary of Meeting:

In disease states, immune cells must compete for available resources to control tissue homeostasis or mediate protective functions. This is particularly true in cancer, where rapidly proliferating and metabolically dysregulated tumors exert metabolic pressure on cells within the tumor microenvironment. Understanding how immune and non-immune cells respond to these conditions and restrain tumor growth and metastasis is critical for developing new cancer therapies. Often cancer biologists and immunologists have little crossover, and this presents a significant barrier to furthering knowledge. This interdisciplinary conference brings together immunologists and scientists focusing on cancer to reveal novel and integrated mechanistic underpinnings that lead to cancer progression/regression and metastasis. Our goals are to: Integrate cancer biologists and immunologists who have a common interest in how cellular metabolism influences cell function; raise awareness of the metabolic intersection between tumor biology and immunology; and encourage junior researchers to actively participate at this interface. Attendees will leave the conference with a stronger understanding of how metabolism in immune cells and non-immune cells influence cell function in metastasis and the tumor microenvironment. We hope that researchers from cancer biology and immunology will, as a result of their interactions, forge new collaborations founded in their mutual appreciation that engagement of particular metabolic pathways shapes cell function and fate. Given the resurgence that metabolism has seen in recent years, we think our conference will appeal broadly to many researchers across cancer biology and immunology, many of whom are interested in investigating metabolic changes in their particular systems.

Scholarship Deadline: November 28 2018

Discounted Abstract Deadline: November 28 2018

Abstract Deadline: December 11 2018

Discounted Registration Deadline: January 17 2019

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support from these exhibitors at this conference:

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.

We gratefully acknowledge the generous grant for this conference provided by:

National Cancer Institute (NCI)
Grant No. 1R13CA239615-01
Funding for this conference was made possible (in part) by 1R13CA239615-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

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