Web Desc
Leveraging Genomic Diversity to Promote Animal and Human Health
Organizer(s): Michèle Ramsay, Han Brunner and Appolinaire Djikeng
Date: November 25 - 29, 2018
Location: Speke Resort & Conference Centre, Kampala, Uganda
Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation
For important information on the coronavirus, please click here
Summary of Meeting:
Genomic variation is a driving force of animal and human health, and susceptibility to disease. Yet our knowledge rarely spans human ethnic genomic diversity and genomic variation between animal breeds, limiting their translational impact. This symposium aims to: 1) Highlight translational genomics in humans and animals (clinical medicine and animal breeding for health and productivity; 2) Explore synergies and cross-disciplinary learning; 3) Explore opportunities to leverage genomic diversity to push the current boundaries to translation; and 4) Address translation and affordability in low- and middle-income settings. Large-scale genomics initiatives like Genome England, the US Precision Medicine initiative, and the Human Heredity and Health in African Consortium are providing extraordinarily large data sets to explore useful genotype-phenotype connections. Equivalent initiatives for animal data are starting. This meeting will explore the translation of genomic research in animals and humans, high and low-resourced environments, ethnic diversity, and cultural context. Identifying common strands in animal and human health opens up opportunities for repurposing of ideas and applications, and for finding innovative solutions for translational genomics through cross-boundary communities of practice.
Global Health Travel Award Deadline: June 26 2018
Scholarship Deadline: August 8 2018
Discounted Abstract Deadline: August 8 2018
Abstract Deadline: August 23 2018
Discounted Registration Deadline: October 6 2018
Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.


Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Bill & Melinda Gates Foundation
We gratefully acknowledge additional support from these exhibitors at this conference:
inqaba biotec
We gratefully acknowledge the generous grant for this conference provided by:

National Human Genome Research Institute (NHGRI)
Grant No. 1 R13 HG010287-01
Funding for this conference was made possible (in part) by 1 R13 HG010287-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, November 25 | 4:00PM - 8:00PM
Arrival and Registration
Room: Victoria Ballroom Foyer


Sunday, November 25 | 6:00PM - 8:00PM
Welcome Mixer
Room: Majestic Hall
No registration fees are used to fund alcohol served at this function.

Monday, November 26 | 9:00AM - 10:30AM
Welcome and Keynote Address
Room: Victoria Ballroom

Speaker 1 of 3
* Michèle Ramsay, University of Witwatersrand, South Africa

Monday, November 26 | 9:00AM - 10:30AM
Welcome and Keynote Address
Room: Victoria Ballroom

Speaker 2 of 3
Evan E. Eichler, HHMI/University of Washington, USA
Relevance of Primate Evolution to Human and Animal Diversity

Monday, November 26 | 9:00AM - 10:30AM
Welcome and Keynote Address
Room: Victoria Ballroom


Coffee Break

Monday, November 26 | 11:00AM - 12:00PM
Genomic Diversity in Health
Room: Victoria Ballroom

Speaker 1 of 2
* Han G. Brunner, Radboud Maastricht University Medical Center, Netherlands

Monday, November 26 | 11:00AM - 12:00PM
Genomic Diversity in Health
Room: Victoria Ballroom

Speaker 2 of 2
Charles N. Rotimi, NHGRI, National Institutes of Health, USA
Global Genomic Diversity: History, Adaptation and Health

Monday, November 26 | 12:00PM - 5:00PM
On Own for Lunch


Monday, November 26 | 12:00PM - 1:00PM
Poster Setup
Room: Victoria Ballroom


Monday, November 26 | 1:00PM - 10:00PM
Poster Viewing
Room: Victoria Ballroom


Monday, November 26 | 3:00PM - 4:30PM
Workshop: Impact of Animal Pathogens on Human Health
Room: Victoria Ballroom

Speaker 1 of 6
* Evan E. Eichler, HHMI/University of Washington, USA

Monday, November 26 | 3:00PM - 4:30PM
Workshop: Impact of Animal Pathogens on Human Health
Room: Victoria Ballroom

Speaker 2 of 6
Jeremaih Okoro Ijomanta, National Veterinary Research Institute, Nigeria
Continuous Circulation of Human-Derived Pandemic H1N1pdm09 Influenza Virus in Nigerian Pigs: Implication
for Public Health and Pandemic Preparedness


Monday, November 26 | 3:00PM - 4:30PM
Workshop: Impact of Animal Pathogens on Human Health
Room: Victoria Ballroom

Speaker 3 of 6
Elijah Kolawole Oladipo, Adeleke University, Nigeria
Genetic Characterization of H5N1 Influenza A Virus Isolated from Pigs in Ogbomoso, Nigeria

Monday, November 26 | 3:00PM - 4:30PM
Workshop: Impact of Animal Pathogens on Human Health
Room: Victoria Ballroom

Speaker 4 of 6
Patricia Ihuaku Otuh, University of Ibadan, Nigeria
Molecular Analyses Unravel Mycobactrium ulcerans Transmission Pathway from Animal Host and Environment to Human in Ogun State, Nigeria

Monday, November 26 | 3:00PM - 4:30PM
Workshop: Impact of Animal Pathogens on Human Health
Room: Victoria Ballroom

Speaker 5 of 6
Abdul Walusansa, Islamic University in Uganda, Uganda
Non-Typhoidal Salmonella and Zoonotic E. coli as Potential Drivers of Antimicrobial Resistance in Pastoralist Communities in Kasese District, Uganda

Monday, November 26 | 3:00PM - 4:30PM
Workshop: Impact of Animal Pathogens on Human Health
Room: Victoria Ballroom

Speaker 6 of 6
Oluwatoyin Modupe Aladejana, Kings University Odeomu, Nigeria
Occurrence and Multiple-Antibiotics Resistance Profile of Enterobacteriaceae Isolated from Bats Faecal Samples in Osun State, Nigeria

Monday, November 26 | 4:30PM - 5:00PM
Coffee Available
Room: Victoria Ballroom Foyer


Monday, November 26 | 5:00PM - 7:00PM
Human Translational Genomics
Room: Victoria Ballroom

Speaker 1 of 6
* Christian T. Happi, Redeemer's University, Nigeria

Monday, November 26 | 5:00PM - 7:00PM
Human Translational Genomics
Room: Victoria Ballroom

Speaker 2 of 6
Han G. Brunner, Radboud Maastricht University Medical Center, Netherlands
Genetic Diagnosis of Intellectual Disability

Monday, November 26 | 5:00PM - 7:00PM
Human Translational Genomics
Room: Victoria Ballroom

Speaker 3 of 6
Brunhilde Wirth, University Hospital Cologne, Germany
Therapeutic Approaches to SMA: In the Challenges is a Solution

Monday, November 26 | 5:00PM - 7:00PM
Human Translational Genomics
Room: Victoria Ballroom

Speaker 4 of 6
Lea M. Starita, University of Washington, USA
Using Multiplexed Functional Assays to Understand the Effects of Genetic Variation


Monday, November 26 | 5:00PM - 7:00PM
Human Translational Genomics
Room: Victoria Ballroom

Speaker 5 of 6
Mohamed Z. Alimohamed, University Medical Center Groningen, Netherlands
Short Talk: Routine Use of Targeted NGS Panel in a Dutch Cardiomyopathy Cohort

Monday, November 26 | 5:00PM - 7:00PM
Human Translational Genomics
Room: Victoria Ballroom

Speaker 6 of 6
Jorge Da Rocha, University of the Witwatersrand, South Africa
Short Talk: Addressing Cancer Treatment in an African Setting: A Bioinformatics Analysis of Pharmacogenomically Relevant Variants

Monday, November 26 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Victoria Ballroom Foyer
No registration fees are used to fund alcohol served at this function.

Monday, November 26 | 7:30PM - 10:00PM
Poster Session 1
Room: Victoria Ballroom


Tuesday, November 27 | 9:00AM - 12:00PM
Livestock Translational Genomics
Room: Victoria Ballroom

Speaker 1 of 7
* Farai C. Muchadeyi, Agricultural Research Council, South Africa

Tuesday, November 27 | 9:00AM - 12:00PM
Livestock Translational Genomics
Room: Victoria Ballroom

Speaker 2 of 7
Michel A.J. Georges, University of Leige GIGA Institute B34, Belgium
Translation of Animal Genomics to Health: European Perspective

Tuesday, November 27 | 9:00AM - 12:00PM
Livestock Translational Genomics
Room: Victoria Ballroom

Speaker 3 of 7
Susan J. Lamont, Iowa State University, USA
Genomics to Enhance Poultry Health Using Biodiversity

Tuesday, November 27 | 9:00AM - 12:00PM
Livestock Translational Genomics
Room: Victoria Ballroom


Coffee Break

Tuesday, November 27 | 9:00AM - 12:00PM
Livestock Translational Genomics
Room: Victoria Ballroom

Speaker 5 of 7
Appolinaire Djikeng, Centre for Tropical Livestock Genetics and Health, University of Edinburgh, UK
Development of Genomic-Based Tools and Resources for Tropical Animal Productivity and Resilience-Talk to be Delivered by John Hickey

Tuesday, November 27 | 9:00AM - 12:00PM
Livestock Translational Genomics
Room: Victoria Ballroom

Speaker 6 of 7
Vivien Jepchirchir Chebii, Nelson Mandela African Institution of Science and Technology, Tanzania
Short Talk: Exploring Association of Copy Number Variations in Wild African Goats (Capra nubiana) Adaptations

Tuesday, November 27 | 9:00AM - 12:00PM
Livestock Translational Genomics
Room: Victoria Ballroom

Speaker 7 of 7
Edward J. Smith, Virginia Polytechnic Institute and State University, USA
Genomic Characterization of Zambian Indigenous Cattle Breeds

Tuesday, November 27 | 12:00PM - 5:00PM
On Own for Lunch


Tuesday, November 27 | 12:00PM - 1:00PM
Poster Setup
Room: Victoria Ballroom


Tuesday, November 27 | 1:00PM - 10:00PM
Poster Viewing
Room: Victoria Ballroom


Tuesday, November 27 | 4:30PM - 5:00PM
Coffee Available
Room: Victoria Ballroom Foyer


Tuesday, November 27 | 5:00PM - 7:00PM
Technological Innovations for Tomorrow
Room: Victoria Ballroom

Speaker 1 of 5
* Niklas Blomberg, ELIXIR Europe, UK

Tuesday, November 27 | 5:00PM - 7:00PM
Technological Innovations for Tomorrow
Room: Victoria Ballroom

Speaker 2 of 5
Christian T. Happi, Redeemer's University, Nigeria
Genomics in Stemming the Tide of Infectious Epidemics

Tuesday, November 27 | 5:00PM - 7:00PM
Technological Innovations for Tomorrow
Room: Victoria Ballroom

Speaker 3 of 5
Simon Lillico, University of Edinburgh, UK
Editing Livestock Genomes: Harnessing and Expanding Genomic Diversity

Tuesday, November 27 | 5:00PM - 7:00PM
Technological Innovations for Tomorrow
Room: Victoria Ballroom

Speaker 4 of 5
Luísa Pereira, Institute of Molecular Pathology and Immunology of the University of Porto, Portugal
The Power of Local Ancestry Inference Algorithms in Mapping Candidate Genes: The Case Study of African Ancestry Protection against Hemorrhagic Dengue Fever

Tuesday, November 27 | 5:00PM - 7:00PM
Technological Innovations for Tomorrow
Room: Victoria Ballroom

Speaker 5 of 5
Martha Kivecu, KEMRI, Kenya
Short Talk: Evaluation of Plasmodium falciparum Histidine-Rich Protein 2 and 3 Gene Deletions in Kenya

Tuesday, November 27 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Victoria Ballroom Foyer
No registration fees are used to fund alcohol served at this function.

Tuesday, November 27 | 7:30PM - 10:00PM
Poster Session 2
Room: Victoria Ballroom


Wednesday, November 28 | 9:00AM - 12:00PM
Solutions for Implementation of Genomic Tests
Room: Victoria Ballroom

Speaker 1 of 8
* Michèle Ramsay, University of Witwatersrand, South Africa

Wednesday, November 28 | 9:00AM - 12:00PM
Solutions for Implementation of Genomic Tests
Room: Victoria Ballroom

Speaker 2 of 8
Farai C. Muchadeyi, Agricultural Research Council, South Africa
Landscape Genomics as a Tool to Understand Genetic Adaptation to Local Conditions

Wednesday, November 28 | 9:00AM - 12:00PM
Solutions for Implementation of Genomic Tests
Room: Victoria Ballroom

Speaker 3 of 8
John M. Hickey, University of Edinburgh, UK
Modern Breeding Programs for Local and Global Economies

Wednesday, November 28 | 9:00AM - 12:00PM
Solutions for Implementation of Genomic Tests
Room: Victoria Ballroom


Coffee Break

Wednesday, November 28 | 9:00AM - 12:00PM
Solutions for Implementation of Genomic Tests
Room: Victoria Ballroom

Speaker 5 of 8
David Evans, University of Queensland, Australia
Using Genetics to Investigate the Developmental Origins of Health and Disease

Wednesday, November 28 | 9:00AM - 12:00PM
Solutions for Implementation of Genomic Tests
Room: Victoria Ballroom

Speaker 6 of 8
Elizabeth Sibongile Tshabalala, Council of Scientific and Industrial Research, South Africa
Short Talk: Genetic Diversity of Pharmacogenes in a Bantu-Speaking Cohort and Evaluation of Variants Associated with Tenofovir-Induced Nephrotoxicity

Wednesday, November 28 | 9:00AM - 12:00PM
Solutions for Implementation of Genomic Tests
Room: Victoria Ballroom

Speaker 7 of 8
Liberata Mwita, Muhimbili University of Health and Allied Sciences, Tanzania
Short Talk: Genome-Wide Associations of Liver Function in Sickle Cell Patients in Tanzania

Wednesday, November 28 | 9:00AM - 12:00PM
Solutions for Implementation of Genomic Tests
Room: Victoria Ballroom

Speaker 8 of 8
Chiaka I. Anumudu, University of Ibadan, Nigeria
Short Talk: Improving Schistosomiasis Control Using Genomics and Proteomics Tools

Wednesday, November 28 | 12:00PM - 5:00PM
On Own for Lunch


Wednesday, November 28 | 12:00PM - 1:00PM
Poster Setup
Room: Victoria Ballroom


Wednesday, November 28 | 1:00PM - 10:00PM
Poster Viewing
Room: Victoria Ballroom


Wednesday, November 28 | 3:30PM - 4:30PM
Virtual Lab Tour: Makerere University
Room: Victoria Ballroom
Come view the labs virtually and meet local researchers, Professor Moses Joloba and Dr. David Kateete, representing the following:
Genomics and Molecular Biology facilities

Bioinformatics/Computational Infrastructure

H3Africa Biorepository

Mycobacteriology Laboratory

Immunology facilities

Bacteriology facilities

Wednesday, November 28 | 4:30PM - 5:00PM
Coffee Available
Room: Victoria Ballroom Foyer


Wednesday, November 28 | 5:00PM - 7:00PM
Genomics in Animal and Human Health
Room: Victoria Ballroom

Speaker 1 of 5
* Han G. Brunner, Radboud Maastricht University Medical Center, Netherlands

Wednesday, November 28 | 5:00PM - 7:00PM
Genomics in Animal and Human Health
Room: Victoria Ballroom

Speaker 2 of 5
Mark S. Fife, Pirbright Institute, UK
Genetic Diversity of Immune Loci in Chickens across Africa and Europe

Wednesday, November 28 | 5:00PM - 7:00PM
Genomics in Animal and Human Health
Room: Victoria Ballroom

Speaker 3 of 5
Michèle Ramsay, University of Witwatersrand, South Africa
Impact of Demographic History and Local Adaptation on Population Diversity and Health: Studies from Africa

Wednesday, November 28 | 5:00PM - 7:00PM
Genomics in Animal and Human Health
Room: Victoria Ballroom

Speaker 4 of 5
Soanandrasana Rahelinirina, Institut Pasteur de Madagascar, Madagascar
Short Talk: First Molecular Detection of Pathogenic Leptospira in Livestock from Slaughterhouses in Madagascar

Wednesday, November 28 | 5:00PM - 7:00PM
Genomics in Animal and Human Health
Room: Victoria Ballroom

Speaker 5 of 5
Isoken H. Igbinosa, University of Benin, Nigeria
Short Talk: Characterization and Detection of Antibiotic Resistance, Virulence Gene Elements and Biofilm Formation in Aeromonas Species Isolated from Cattle

Wednesday, November 28 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Victoria Ballroom Foyer
No registration fees are used to fund alcohol served at this function.

Wednesday, November 28 | 7:30PM - 10:00PM
Poster Session 3
Room: Victoria Ballroom


Thursday, November 29 | 9:00AM - 12:00PM
Enablers for Translational Genomics
Room: Victoria Ballroom

Speaker 1 of 6
Niklas Blomberg, ELIXIR Europe, UK
Global Data Infrastructure for the Scientific Enterprise

Thursday, November 29 | 9:00AM - 12:00PM
Enablers for Translational Genomics
Room: Victoria Ballroom

Speaker 2 of 6
Bassirou Bonfoh, CSRS/Afrique One-African Science Partnership for Intervention Research Excellence, Côte D'Ivoire
Genomics: A Half-Full Glass in One Health

Thursday, November 29 | 9:00AM - 12:00PM
Enablers for Translational Genomics
Room: Victoria Ballroom


Coffee Break

Thursday, November 29 | 9:00AM - 12:00PM
Enablers for Translational Genomics
Room: Victoria Ballroom

Speaker 4 of 6
Nicholas Katsanis, Northwestern University Feinberg School of Medicine, USA
Zebrafish Models for Diseases

Thursday, November 29 | 9:00AM - 12:00PM
Enablers for Translational Genomics
Room: Victoria Ballroom

Speaker 5 of 6
Jim Kaufman, University of Cambridge, UK
Short Talk: Typing MHC Haplotypes of African Village Chickens for Structure-Function Studies

Thursday, November 29 | 9:00AM - 12:00PM
Enablers for Translational Genomics
Room: Victoria Ballroom

Speaker 6 of 6
Acho Fon Abongwa, Elizabeth Glaser Pediatric AIDS Foundation, Cameroon
Short Talk: Evolution of Plasmodium Falciparum Strains and Resistance Markers in Pregnant Women in Cameroon: 2008-2018

Thursday, November 29 | 12:00PM - 5:00PM
On Own for Lunch


Thursday, November 29 | 2:30PM - 3:30PM
Panel Discussion: How Do We Build the Ideal Cattle Breeds fo
r Different Ecological Niches?
Room: Victoria Ballroom

Speaker 1 of 3
* John M. Hickey, University of Edinburgh, UK

Thursday, November 29 | 2:30PM - 3:30PM
Panel Discussion: How Do We Build the Ideal Cattle Breeds fo
r Different Ecological Niches?
Room: Victoria Ballroom

Speaker 2 of 3
Sumaya Y. Kambal, Sudan University of Science and Technology, Sudan
Mitogenomic Analysis of Western Baggara Cattle Breed-Nyalawi Population

Thursday, November 29 | 2:30PM - 3:30PM
Panel Discussion: How Do We Build the Ideal Cattle Breeds fo
r Different Ecological Niches?
Room: Victoria Ballroom

Speaker 3 of 3
Owen Powell, Roslin Institute, University of Edinburgh, Scotland
Can Genomics Enable Genetic Evaluations with Phenotypes Recorded on Smallholder Dairy Farms?

Thursday, November 29 | 3:30PM - 4:30PM
Panel Discussion: What Do We Need to Know About Our Ancestry
?
Room: Victoria Ballroom

Speaker 1 of 1
* Han G. Brunner, Radboud Maastricht University Medical Center, Netherlands

Thursday, November 29 | 4:30PM - 5:00PM
Coffee Available
Room: Victoria Ballroom Foyer


Thursday, November 29 | 5:00PM - 6:45PM
Toward a Perfect World – Emerging Themes
Room: Victoria Ballroom

Speaker 1 of 3
* Charles N. Rotimi, NHGRI, National Institutes of Health, USA

Thursday, November 29 | 5:00PM - 6:45PM
Toward a Perfect World – Emerging Themes
Room: Victoria Ballroom

Speaker 2 of 3
Elizabeth Marincola, African Academy of Sciences, Kenya
How African Researchers Can Lead the Way in Global Science Communication

Thursday, November 29 | 5:00PM - 6:45PM
Toward a Perfect World – Emerging Themes
Room: Victoria Ballroom

Speaker 3 of 3
Alison L. Van Eenennaam, University of California, Davis, USA
Public Perception of Animal Biotechnology

Thursday, November 29 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Victoria Ballroom


Thursday, November 29 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Poolside Lawn
No registration fees are used to fund alcohol served at this function.

Thursday, November 29 | 8:00PM - 11:00PM
Entertainment
Room: Poolside Lawn
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, November 29 | 8:00PM - 11:00PM
Cash Bar
Room: Poolside Lawn


Friday, November 30 | 10:24AM - 10:24AM
Departure


*Session Chair
†Invited, not yet responded.