Web Desc
Neural Environment in Disease: Glial Responses and Neuroinflammation
joint with Neurodegenerative Diseases: New Insights and Therapeutic Opportunities
Organizer(s): Richard Daneman, Dorothy Schafer, Michael V. Sofroniew and Vanda A. Lennon
Date: June 16 - 20, 2019
Location: Keystone Resort, Keystone, CO, USA
Sponsored by BioLegend, Inc.
Summary of Meeting:
The response of the central nervous system to injury and disease is a complex physiological process that involves the coordinated actions of many different cell types. The interplay of neural cells and vascular cells along with the innate and adaptive immune systems determines the response to different injury and disease stimuli and whether the central nervous system will repair or degenerate. Understanding this complex cellular environment is essential to understanding disease pathogenesis, elucidating underlying disease etiology, and developing treatments for neurological and psychiatric diseases. The goal of this conference will be to bring together people who study different aspects of neurological diseases and facilitate the interchange of ideas necessary for identifying new mechanisms underlying complex intercellular interactions in the diseased nervous system. This will include people who study resident neural cells (neurons, astrocytes, oligodendrocytes), vascular cells (blood-brain barrier, lymphatics, glymphatics) and immune cells (microglia, innate peripheral immune cells, adaptive immune cells) in the context of a variety of neurodegenerative, neuroinflammatory, and neuropsychiatric diseases. Further, we will also attract people who implement different techniques including genetic mouse models, human iPSCs, invertebrate models, imaging, cell biology, and behavior in their research which will further facilitate exchange of ideas and foster collaboration. With the combined expertise at this conference, we will accelerate our ability to understand the complex neural response to injury and disease, which is a necessary step towards developing novel therapeutics for complex neurological diseases.
Scholarship Deadline: February 13 2019
Discounted Abstract Deadline: February 13 2019
Abstract Deadline: March 13 2019
Discounted Registration Deadline: April 16 2019
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
BioLegend, Inc.
We gratefully acknowledge additional support from these exhibitors at this conference:
Antibodies IncorporatedMilliporeSigma
We gratefully acknowledge additional support for this conference from:
Integra FoundationNeuroscience Next
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Neurological Disorders and Stroke (NINDS)
Grant No. 1R13NS111932-01
Funding for this conference was made possible (in part) by 1R13NS111932-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, June 16 | 4:00PM - 8:00PM
Arrival and Registration
Room: Longs Peak Foyer


Sunday, June 16 | 6:00PM - 8:00PM
Welcome Mixer
Room: Longs Peak Foyer
No registration fees are used to fund alcohol served at this function.

Monday, June 17 | 7:30AM - 8:30AM
Breakfast
Room: Colorado Rockies Ballroom


Monday, June 17 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Quandary Peak

Speaker 1 of 3
* Richard Daneman, University of California, San Diego, USA

Monday, June 17 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Quandary Peak

Speaker 2 of 3
* Dorothy Schafer, University of Massachusetts Medical School, USA

Monday, June 17 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Quandary Peak

Speaker 3 of 3
Li-Huei Tsai, Massachusetts Institute of Technology, USA
Neuron-Glia Interaction in Health and Disease

Monday, June 17 | 9:30AM - 12:00PM
Neuronal Response to Injury
Room: Quandary Peak

Speaker 1 of 6
* David M. Holtzman, Washington University, USA
TREM2 Function Regulates Aß linked Tau Seeding and Spreading in Neuritic Plaques

Monday, June 17 | 9:30AM - 12:00PM
Neuronal Response to Injury
Room: Quandary Peak


Coffee Break

Monday, June 17 | 9:30AM - 12:00PM
Neuronal Response to Injury
Room: Quandary Peak

Speaker 3 of 6
Eric J. Huang, University of California, San Francisco, USA
Neuron-Glia Interaction in Human Germinal Matrix: Implications in Neurodevelopmental Disorders

Monday, June 17 | 9:30AM - 12:00PM
Neuronal Response to Injury
Room: Quandary Peak

Speaker 4 of 6
* Marc R. Freeman, Oregon Health & Science University, USA
Mechanisms of Axon Degeneration

Monday, June 17 | 9:30AM - 12:00PM
Neuronal Response to Injury
Room: Quandary Peak

Speaker 5 of 6
Katie Ennis, Biogen, USA
Short Talk: The Cytokine Receptor Fn14 is Required for Hippocampal Synaptic Plasticity Deficits that Occur Following Acute Ischemic Stroke

Monday, June 17 | 9:30AM - 12:00PM
Neuronal Response to Injury
Room: Quandary Peak

Speaker 6 of 6
Lucas Cheadle, Harvard Medical School, USA
Short Talk: Sensory Experience Engages Microglia-to-Neuron Cytokine Signaling to Remodel Developing Synapses

Monday, June 17 | 9:30AM - 11:45AM
Aggregation Mediated Toxicity
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 1 of 6
* Xiaobo Mao, Johns Hopkins University, USA


Monday, June 17 | 9:30AM - 11:45AM
Aggregation Mediated Toxicity
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 2 of 6
Rudolph E. Tanzi, Massachusetts General Hospital, USA
Amyloid Beta Organoid Model


Monday, June 17 | 9:30AM - 11:45AM
Aggregation Mediated Toxicity
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak


Coffee Break


Monday, June 17 | 9:30AM - 11:45AM
Aggregation Mediated Toxicity
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 4 of 6
Valina L. Dawson, Johns Hopkins University School of Medicine, USA
Alpha Synuclein Toxicity


Monday, June 17 | 9:30AM - 11:45AM
Aggregation Mediated Toxicity
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 5 of 6
Patrik Verstreken, KU Leuven, Belgium
Tau Toxicity at the Synapse


Monday, June 17 | 9:30AM - 11:45AM
Aggregation Mediated Toxicity
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 6 of 6
Thomas Brannstrom, Umea University Hospital, Sweden
Short Talk: Transmissibility of SOD1 Prion Strains Between Mice Expressing Different Mutant Human SOD1s


Monday, June 17 | 12:00PM - 5:00PM
On Own for Lunch


Monday, June 17 | 12:00PM - 1:00PM
Poster Setup
Room: Colorado Rockies Ballroom


Monday, June 17 | 1:00PM - 10:00PM
Poster Viewing
Room: Colorado Rockies Ballroom


Monday, June 17 | 2:30PM - 4:30PM
Workshop 1: Modulating Microglia Inflammatory Signaling
Room: Quandary Peak

Speaker 1 of 10
* Kim N. Green, University of California, Irvine, USA

Monday, June 17 | 2:30PM - 4:30PM
Workshop 1: Modulating Microglia Inflammatory Signaling
Room: Quandary Peak

Speaker 2 of 10
* Iben Lundgaard, University of Lund, Sweden

Monday, June 17 | 2:30PM - 4:30PM
Workshop 1: Modulating Microglia Inflammatory Signaling
Room: Quandary Peak

Speaker 3 of 10
Ying Cao, Peking University, China
Transcriptional Mechanism of IRF8 and PU.1 Governs Microglial Activation in Neurodegenerative Condition

Monday, June 17 | 2:30PM - 4:30PM
Workshop 1: Modulating Microglia Inflammatory Signaling
Room: Quandary Peak

Speaker 4 of 10
Rouven Schulz, Institute of Science and Technology Austria, Austria
Topological Classification of Microglia


Monday, June 17 | 2:30PM - 4:30PM
Workshop 1: Modulating Microglia Inflammatory Signaling
Room: Quandary Peak

Speaker 5 of 10
Yajing Xu, University College London, UK
Microglia Mediate Restructuring of Spinal Somatosensory Circuits During Normal Postnatal Development and After Injury

Monday, June 17 | 2:30PM - 4:30PM
Workshop 1: Modulating Microglia Inflammatory Signaling
Room: Quandary Peak

Speaker 6 of 10
Youtong Huang, University of California, San Diego / Salk Institute, USA
Investigating Microglial TAM Receptors as Modulators of Alzheimer’s Pathology

Monday, June 17 | 2:30PM - 4:30PM
Workshop 1: Modulating Microglia Inflammatory Signaling
Room: Quandary Peak

Speaker 7 of 10
Guy C. Brown, University of Cambridge, UK
Blocking the Microglial P2Y6 Receptor Prevents Microglial Phagocytosis of Neurons and Synapses, and Prevents Neurodegeneration Induced by Neuroinflammation, Beta Amyloid, TAU and Ageing in vivo

Monday, June 17 | 2:30PM - 4:30PM
Workshop 1: Modulating Microglia Inflammatory Signaling
Room: Quandary Peak

Speaker 8 of 10
Monique S. Mendes, University of Rochester, USA
In vivo Imaging of Microglial Self-Renewal and Maturation in the Adult Mouse Brain

Monday, June 17 | 2:30PM - 4:30PM
Workshop 1: Modulating Microglia Inflammatory Signaling
Room: Quandary Peak

Speaker 9 of 10
Nicole Vo, University of Washington, USA
CD33 and CD45 interaction in AD

Monday, June 17 | 2:30PM - 4:30PM
Workshop 1: Modulating Microglia Inflammatory Signaling
Room: Quandary Peak

Speaker 10 of 10
Sanda Mimouna, Hospital for Special Surgery, USA
The Role of Transcriptional Coregulator GRIP1 in Myeloid Cells in Neuroinflammation

Monday, June 17 | 3:00PM - 4:30PM
Workshop 1
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 1 of 7
* David V. Hansen, Genentech, Inc., USA


Monday, June 17 | 3:00PM - 4:30PM
Workshop 1
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 2 of 7
Michael Henderson, University of Pennsylvania, USA
Using Quantitative Pathology Mapping and Network Modeling to Understand a-Synuclein Spread


Monday, June 17 | 3:00PM - 4:30PM
Workshop 1
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 3 of 7
Sang Su Kwak, Genetics and Aging Research Unit, Massachusetts General Hospital, USA
Amyloid-ß 42/40 Ratio Drives Tau Pathology in 3D Human Neural Cell Culture Models of Alzheimer's Disease


Monday, June 17 | 3:00PM - 4:30PM
Workshop 1
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 4 of 7
Evan T. Lester, University of Colorado, USA
Interactions between RNA and Tau in Models of Frontotemporal Dementia


Monday, June 17 | 3:00PM - 4:30PM
Workshop 1
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 5 of 7
Sílvia Porta, Center for Neurodegenerative Disease Research, USA
Patient-Derived Frontotemporal Lobar Degeneration Brain Extracts Induce Formation and Spreading of TDP-43 Pathology in vivo


Monday, June 17 | 3:00PM - 4:30PM
Workshop 1
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 6 of 7
Stephanie K. See, University of California, San Francisco, USA
Identification of Cellular Mechanisms that Control a-Synuclein Aggregation Using a CRISPRi/a Functional Genomics Platform


Monday, June 17 | 3:00PM - 4:30PM
Workshop 1
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 7 of 7
Meghan Kerrisk Campbell, Alkahest, USA
A Therapeutic Human Plasma Fraction Enhances Cognitive Function in Aging and Neurodegenerative Disease through Multiple Mechanisms of Action


Monday, June 17 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Monday, June 17 | 5:00PM - 7:00PM
Transmission and Spread of Disease Pathology
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 1 of 6
* Karen Hsiao Ashe, University of Minnesota, USA


Monday, June 17 | 5:00PM - 7:00PM
Transmission and Spread of Disease Pathology
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 2 of 6
Xiaobo Mao, Johns Hopkins University, USA
The Mechanism of Pathological alpha-synuclein Transmission


Monday, June 17 | 5:00PM - 7:00PM
Transmission and Spread of Disease Pathology
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 3 of 6
John Collinge, University College London, UK
Prion Neurodegeneration: Towards an Effective Treatment and its Relevance for Alzheimer’s Disease


Monday, June 17 | 5:00PM - 7:00PM
Transmission and Spread of Disease Pathology
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 4 of 6
Karina Fog, H. Lundbeck A/S, Denmark
Alpha-Synuclein Antibodies as Therapeutics in Synucleinopathies – How Antibodies Affect Cellular Handling of Misfolded alpha-synuclein


Monday, June 17 | 5:00PM - 7:00PM
Transmission and Spread of Disease Pathology
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 5 of 6
Amanda Engstrom, Emory University, USA
Short Talk: Pathological Tau Induces Neurodegeneration Through the Sequestration and Inhibition of LSD1 Function


Monday, June 17 | 5:00PM - 7:00PM
Transmission and Spread of Disease Pathology
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 6 of 6
Xuyuan Kuang, Rutgers University, USA
Short Talk: Association of Transmissive PolyQ Aggregates with Lipid Vesicles and Its Implications in Mutant Huntingtin Seeding


Monday, June 17 | 5:00PM - 7:00PM
Astrocytes
Room: Quandary Peak

Speaker 1 of 4
Michael V. Sofroniew, University of California, Los Angeles, USA
Astrocyte Roles in Repair and Regeneration

Monday, June 17 | 5:00PM - 7:00PM
Astrocytes
Room: Quandary Peak

Speaker 2 of 4
* Jin-Moo Lee, Washington University, USA
Astrocytosis and Amyloid Plaque Pathogenesis

Monday, June 17 | 5:00PM - 7:00PM
Astrocytes
Room: Quandary Peak

Speaker 3 of 4
* Cagla Eroglu, Duke University Medical Center, USA
How do Glia Sculpt Synaptic Circuits?

Monday, June 17 | 5:00PM - 7:00PM
Astrocytes
Room: Quandary Peak

Speaker 4 of 4
Blanca Diaz Castro, University of Edinburgh, UK
Striatal Astrocytes: Identity, Form, Function and Roles in Huntington’s Disease

Monday, June 17 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Monday, June 17 | 7:30PM - 10:00PM
Poster Session 1
Room: Colorado Rockies Ballroom


Tuesday, June 18 | 7:30AM - 8:30AM
Breakfast
Room: Colorado Rockies Ballroom


Tuesday, June 18 | 8:30AM - 11:45AM
Microglia and Innate Immunity
Room: Quandary Peak

Speaker 1 of 8
Dorothy Schafer, University of Massachusetts Medical School, USA
Targeting Microglia-Mediated Synapse Loss for Therapeutic Intervention in Multiple Sclerosis

Tuesday, June 18 | 8:30AM - 11:45AM
Microglia and Innate Immunity
Room: Quandary Peak

Speaker 2 of 8
Kim N. Green, University of California, Irvine, USA
Microglia Facilitate Plaque Development and Mediate the Downregulation of Synaptic Genes in Alzheimer’s Disease Mice

Tuesday, June 18 | 8:30AM - 11:45AM
Microglia and Innate Immunity
Room: Quandary Peak


Coffee Break

Tuesday, June 18 | 8:30AM - 11:45AM
Microglia and Innate Immunity
Room: Quandary Peak

Speaker 4 of 8
* Anne Schaefer, Mount Sinai School of Medicine, USA
Epigenetic and Signaling Controlled Brain Region-Specific Microglia Functions

Tuesday, June 18 | 8:30AM - 11:45AM
Microglia and Innate Immunity
Room: Quandary Peak

Speaker 5 of 8
* Francisco J. Quintana, Harvard Medical School, USA
Molecular Control of Astrocyte Pathogenic Activities in MS

Tuesday, June 18 | 8:30AM - 11:45AM
Microglia and Innate Immunity
Room: Quandary Peak

Speaker 6 of 8
Serena Becchi, University of New South Wales, Australia
Short Talk: The Role of Microglia when Decision Making is Impaired by a High Fat and Sugar Diet in Rats

Tuesday, June 18 | 8:30AM - 11:45AM
Microglia and Innate Immunity
Room: Quandary Peak

Speaker 7 of 8
Manana Kutsia, Okinawa Institute of Science and Technology Graduate University, Japan
Short Talk: Importance of Microglia for Neural Tissue Regeneration in Zebrafish Model of Traumatic Brain Injury

Tuesday, June 18 | 8:30AM - 11:45AM
Microglia and Innate Immunity
Room: Quandary Peak

Speaker 8 of 8
Sandra Siegert, Institute of Science and Technology Austria, Austria
Short Talk: Sex Specific Microglia Response to Transient Reduction of Neuronal Activity

Tuesday, June 18 | 8:30AM - 11:45AM
New Therapeutic Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 1 of 9
* Joseph W. Lewcock, Denali Therapeutics, USA


Tuesday, June 18 | 8:30AM - 11:45AM
New Therapeutic Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 2 of 9
Frank Rigo, Ionis Pharmaceuticals, USA
RNA Targeting Therapeutics for the Treatment of Neurodegenerative Diseases


Tuesday, June 18 | 8:30AM - 11:45AM
New Therapeutic Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 3 of 9
Eric J. Huang, University of California, San Francisco, USA
Microglia Toxicity and TDP-43 Proteinopathy in Neurodegeneration


Tuesday, June 18 | 8:30AM - 11:45AM
New Therapeutic Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak


Coffee Break


Tuesday, June 18 | 8:30AM - 11:45AM
New Therapeutic Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 5 of 9
Don W. Cleveland, University of California, San Diego, USA
Gene Silencing Therapy for Neurodegenerative Disease


Tuesday, June 18 | 8:30AM - 11:45AM
New Therapeutic Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 6 of 9
Li Gan, Weill Cornell Medicine, USA
Sex-Dimorphic Effects of Microglial Dysfunction in Neurodegeneration


Tuesday, June 18 | 8:30AM - 11:45AM
New Therapeutic Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 7 of 9
Dieter Willbold, Forschungszentrum Jülich, Germany
Short Talk: First Clinical Data of the First Anti-Prionic PRI-002 that is Orally Available, Reverts Cognition Deficits, and Decelerates Neurodegeneration in Transgenic AD Mouse Models


Tuesday, June 18 | 8:30AM - 11:45AM
New Therapeutic Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 8 of 9
Daniel Heinzer, University of Zurich, Switzerland
Short Talk: Whole Genome RNAi Screen Identifies Novel Regulators of PrPC as Potential Therapeutic Targets in Prion Diseases


Tuesday, June 18 | 8:30AM - 11:45AM
New Therapeutic Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 9 of 9
Alessandro Sette, La Jolla Institute for Immunology, USA
Short Talk: T Cell Reactivity to Tau and Alpha-Synuclein in PD


Tuesday, June 18 | 11:45AM - 5:00PM
On Own for Lunch


Tuesday, June 18 | 11:45AM - 1:00PM
Poster Setup
Room: Colorado Rockies Ballroom


Tuesday, June 18 | 1:00PM - 10:00PM
Poster Viewing
Room: Colorado Rockies Ballroom


Tuesday, June 18 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Tuesday, June 18 | 5:00PM - 7:00PM
Blood Brain Barrier
Room: Quandary Peak

Speaker 1 of 5
Richard Daneman, University of California, San Diego, USA
Regulation of the Blood-Brain Barrier in Health and Disease

Tuesday, June 18 | 5:00PM - 7:00PM
Blood Brain Barrier
Room: Quandary Peak

Speaker 2 of 5
* Alexandre Prat, Université de Montréal, Canada
Influence of Cytokines on the Blood-Brain Barrier

Tuesday, June 18 | 5:00PM - 7:00PM
Blood Brain Barrier
Room: Quandary Peak

Speaker 3 of 5
* Eric V. Shusta, University of Wisconsin-Madison, USA
Modeling the Neurovascular Unit Using Human iPSCs

Tuesday, June 18 | 5:00PM - 7:00PM
Blood Brain Barrier
Room: Quandary Peak

Speaker 4 of 5
Sidar Aydin, University of Bern, Switzerland
Short Talk: Endothelial Antigen-Presentation Stops the Migration of CD8+ T Cells Across the Blood-Brain Barrier in Neuroinflammation

Tuesday, June 18 | 5:00PM - 7:00PM
Blood Brain Barrier
Room: Quandary Peak

Speaker 5 of 5
Matthew N. McCarroll, University of California, San Francisco, USA
Short Talk: An Inducible Zebrafish Model of Pineal Gland Ablation Reveals Dynamics of Neuronal Cell Death, Regeneration and Microgliosis in vivo

Tuesday, June 18 | 5:00PM - 7:00PM
Developing Effective Preclinical Disease Models
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 1 of 5
* Valina L. Dawson, Johns Hopkins University School of Medicine, USA


Tuesday, June 18 | 5:00PM - 7:00PM
Developing Effective Preclinical Disease Models
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 2 of 5
Martin Kampmann, University of California, San Francisco, USA
Elucidating Cellular Mechanisms and Therapeutic Strategies for Neurodegenerative Diseases with Multimodal CRISPR-based Genetic Screens in iPSC-Derived Neurons and Glia


Tuesday, June 18 | 5:00PM - 7:00PM
Developing Effective Preclinical Disease Models
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 3 of 5
Elena Cattaneo, University of Milano, Italy
Organiod Models of Triple Repeat Diseases


Tuesday, June 18 | 5:00PM - 7:00PM
Developing Effective Preclinical Disease Models
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 4 of 5
Fred H. Gage, The Salk Institute for Biological Studies, USA
iPSC to Study Repair and Neurodegeneration


Tuesday, June 18 | 5:00PM - 7:00PM
Developing Effective Preclinical Disease Models
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 5 of 5
Zhuohao He, University of Pennsylvania, USA
Short Talk: Studying Tau Transmission in AD and FTLD Using Novel Mouse Models


Tuesday, June 18 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Tuesday, June 18 | 7:30PM - 10:00PM
Poster Session 2
Room: Colorado Rockies Ballroom


Wednesday, June 19 | 7:30AM - 8:30AM
Breakfast
Room: Colorado Rockies Ballroom


Wednesday, June 19 | 8:30AM - 11:45AM
Glymphatics and Lymphatics
Room: Quandary Peak

Speaker 1 of 8
* Kari K. Alitalo, University of Helsinki, Finland
CNS Lymphatics

Wednesday, June 19 | 8:30AM - 11:45AM
Glymphatics and Lymphatics
Room: Quandary Peak

Speaker 2 of 8
Iben Lundgaard, University of Lund, Sweden
Glymphatics

Wednesday, June 19 | 8:30AM - 11:45AM
Glymphatics and Lymphatics
Room: Quandary Peak


Coffee Break

Wednesday, June 19 | 8:30AM - 11:45AM
Glymphatics and Lymphatics
Room: Quandary Peak

Speaker 4 of 8
Maria Lehtinen, Harvard Medical School, USA
Orchestration of Embryonic Brain Development by the Choroid Plexus

Wednesday, June 19 | 8:30AM - 11:45AM
Glymphatics and Lymphatics
Room: Quandary Peak

Speaker 5 of 8
* Julie Siegenthaler, University of Colorado Denver, USA
Meningeal Fibroblast Identity and Function: New Insights from scRNA-Sequencing

Wednesday, June 19 | 8:30AM - 11:45AM
Glymphatics and Lymphatics
Room: Quandary Peak

Speaker 6 of 8
Percy Griffin, Washington University in St. Louis, USA
Short Talk: Circadian Regulation of Neuroinflammation and Neurodegeneration by Rev-Erba

Wednesday, June 19 | 8:30AM - 11:45AM
Glymphatics and Lymphatics
Room: Quandary Peak

Speaker 7 of 8
Celia McKee, Washington University in St. Louis, USA
Short Talk: The Astrocyte Circadian Clock Regulates Amyloid Beta Deposition and Degradation

Wednesday, June 19 | 8:30AM - 11:45AM
Glymphatics and Lymphatics
Room: Quandary Peak

Speaker 8 of 8
Caio Mazucanti, NIA, National Institutes of Health, USA
Short Talk: Serotonergic Regulation of Insulin Expression & Release in Choroid Plexus

Wednesday, June 19 | 8:30AM - 11:30AM
Translating Therapeutics for Neurodegeneration to the Clinic
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 1 of 8
* Karina Fog, H. Lundbeck A/S, Denmark


Wednesday, June 19 | 8:30AM - 11:30AM
Translating Therapeutics for Neurodegeneration to the Clinic
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 2 of 8
Joseph W. Lewcock, Denali Therapeutics, USA
Therapeutic Strategies Based on Human Genetics


Wednesday, June 19 | 8:30AM - 11:30AM
Translating Therapeutics for Neurodegeneration to the Clinic
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 3 of 8
Matthew Kennedy, Merck Research Labs, USA
Discovery and Development of LRRK2 Inhibitors


Wednesday, June 19 | 8:30AM - 11:30AM
Translating Therapeutics for Neurodegeneration to the Clinic
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak


Coffee Break


Wednesday, June 19 | 8:30AM - 11:30AM
Translating Therapeutics for Neurodegeneration to the Clinic
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 5 of 8
David V. Hansen, Genentech, Inc., USA
Microglial Activation States in Alzheimer's Disease: Are You a (Wo)man or a Mouse?


Wednesday, June 19 | 8:30AM - 11:30AM
Translating Therapeutics for Neurodegeneration to the Clinic
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 6 of 8
Jeffrey L. Cleland, Orpheris, Inc., USA
Short Talk: OP-101: Human Safety and Pharmacokinetics of a Microglia-targeted Systemic Therapy for Neuroinflammation


Wednesday, June 19 | 8:30AM - 11:30AM
Translating Therapeutics for Neurodegeneration to the Clinic
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 7 of 8
Anna Ettorre, 4D Pharma Research Ltd., UK
Short Talk: From Screening to Pre-Clinical Efficacy of Microbiome-Derived Bacterial Strains that Modulate Neuroinflammatory and Neurodegenerative Processes in Parkinson's Disease


Wednesday, June 19 | 8:30AM - 11:30AM
Translating Therapeutics for Neurodegeneration to the Clinic
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 8 of 8
Garrett S. Gibbons, University of Pennsylvania, USA
Short Talk: Conformation-Selective Tau Monoclonal Antibodies as Immunotherapy Candidates for Alzheimer's Disease (AD)
and Frontotemporal Lobar Degeneration-tau (FTLD-tau)


Wednesday, June 19 | 11:45AM - 5:00PM
On Own for Lunch


Wednesday, June 19 | 11:45AM - 1:00PM
Poster Setup
Room: Colorado Rockies Ballroom


Wednesday, June 19 | 1:00PM - 10:00PM
Poster Viewing
Room: Colorado Rockies Ballroom


Wednesday, June 19 | 2:30PM - 4:30PM
Round Table Discussion from Industry, Government and Academi
a - Challenges and Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 1 of 6
* Joseph W. Lewcock, Denali Therapeutics, USA


Wednesday, June 19 | 2:30PM - 4:30PM
Round Table Discussion from Industry, Government and Academi
a - Challenges and Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 2 of 6
Gene W. Yeo, University of California, San Diego, USA


Wednesday, June 19 | 2:30PM - 4:30PM
Round Table Discussion from Industry, Government and Academi
a - Challenges and Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 3 of 6
Matthew Kennedy, Merck Research Labs, USA


Wednesday, June 19 | 2:30PM - 4:30PM
Round Table Discussion from Industry, Government and Academi
a - Challenges and Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 4 of 6
Frank Rigo, Ionis Pharmaceuticals, USA


Wednesday, June 19 | 2:30PM - 4:30PM
Round Table Discussion from Industry, Government and Academi
a - Challenges and Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 5 of 6
Amir Tamiz, NINDS, National Institutes of Health, USA


Wednesday, June 19 | 2:30PM - 4:30PM
Round Table Discussion from Industry, Government and Academi
a - Challenges and Opportunities
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 6 of 6
Aaron D. Gitler, Stanford University School of Medicine, USA


Wednesday, June 19 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Wednesday, June 19 | 5:00PM - 7:00PM
Adaptive Immune Responses
Room: Quandary Peak

Speaker 1 of 5
Vanda A. Lennon, Mayo Clinic, USA
Astrocytic and Oligodendroglial Autoimmunity

Wednesday, June 19 | 5:00PM - 7:00PM
Adaptive Immune Responses
Room: Quandary Peak

Speaker 2 of 5
* Daniel S. Reich, NINDS, National Institutes of Health, USA
Imaging Lesion Repair in Multiple Sclerosis

Wednesday, June 19 | 5:00PM - 7:00PM
Adaptive Immune Responses
Room: Quandary Peak

Speaker 3 of 5
* Jorge I. Alvarez, University of Pennsylvania, USA
CNS Intrinsic Mechanisms Suppressing T Cell Driven Neuroinflammation

Wednesday, June 19 | 5:00PM - 7:00PM
Adaptive Immune Responses
Room: Quandary Peak

Speaker 4 of 5
Keita Saeki, National Institutes of Health, USA
Short Talk: IRF8 Shapes Long-Term Endotoxin Memory in Microglia

Wednesday, June 19 | 5:00PM - 7:00PM
Adaptive Immune Responses
Room: Quandary Peak

Speaker 5 of 5
Tiffany J. Petrisko, West Virginia University, USA
Short Talk: CXCL10-CXCR3 Axis Mediates Induction of Cerebral Hyperexcitability by Peripheral Viral Challenge

Wednesday, June 19 | 5:00PM - 7:00PM
Molecular Mechanisms of ALS/FTD
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 1 of 6
* Shanthini Sockanathan, Johns Hopkins University School of Medicine, USA


Wednesday, June 19 | 5:00PM - 7:00PM
Molecular Mechanisms of ALS/FTD
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 2 of 6
Aaron D. Gitler, Stanford University School of Medicine, USA
Expanding Mechanisms and Therapeutic Targets for Neurodegenerative Disease


Wednesday, June 19 | 5:00PM - 7:00PM
Molecular Mechanisms of ALS/FTD
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 3 of 6
Clotilde Lagier-Tourenne, Massachusetts General Hospital, USA
Molecular Mechanisms of Disease in ALS and FTD


Wednesday, June 19 | 5:00PM - 7:00PM
Molecular Mechanisms of ALS/FTD
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 4 of 6
Gene W. Yeo, University of California, San Diego, USA
Protein-RNA and Stress Granules Dysregulation in ALS


Wednesday, June 19 | 5:00PM - 7:00PM
Molecular Mechanisms of ALS/FTD
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 5 of 6
Hideyuki Takahashi, Yale University, USA
Short Talk: Progranulin Deficiency Induces Expression of Microglial TYROBP Gene Network and Differentially affects Alzheimer's disease pathologies


Wednesday, June 19 | 5:00PM - 7:00PM
Molecular Mechanisms of ALS/FTD
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 6 of 6
Evangelos Kiskinis, Northwestern University Feinberg School of Medicine, USA
Short Talk: Nucleocytoplasmic Proteomic Analysis Highlights ETF1 and Nonsense Mediated Decay as Therapeutic Targets in
C9ORF72-Related ALS/FTD


Wednesday, June 19 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Wednesday, June 19 | 7:30PM - 10:00PM
Poster Session 3
Room: Colorado Rockies Ballroom


Thursday, June 20 | 7:30AM - 8:30AM
Breakfast
Room: Colorado Rockies Ballroom


Thursday, June 20 | 8:30AM - 11:30AM
Oligodendrocytes and Inflammation
Room: Quandary Peak

Speaker 1 of 7
David H. Rowitch, University of Cambridge, UK
Neuronal Vulnerability and Multilineage Diversity in Multiple Sclerosis


Thursday, June 20 | 8:30AM - 11:30AM
Oligodendrocytes and Inflammation
Room: Quandary Peak

Speaker 2 of 7
* Kelly Monk, Oregon Health & Science University, USA
Molecular and Genetic Mechanisms of Myelin Formation and Repair

Thursday, June 20 | 8:30AM - 11:30AM
Oligodendrocytes and Inflammation
Room: Quandary Peak


Coffee Break

Thursday, June 20 | 8:30AM - 11:30AM
Oligodendrocytes and Inflammation
Room: Quandary Peak

Speaker 4 of 7
Dimitry Ofengeim, Sanofi, USA
Understanding the Nature of Microglial Phenotypes through the Interplay of Cell Death and Inflammation

Thursday, June 20 | 8:30AM - 11:30AM
Oligodendrocytes and Inflammation
Room: Quandary Peak

Speaker 5 of 7
Stefan Berghoff, Max-Planck Institut for Experimental Medicine, Germany
Short Talk: Cell-Type Specific Cholesterol Synthesis Coordinates Inflammation and Remyelination in Demyelinated Lesions

Thursday, June 20 | 8:30AM - 11:30AM
Oligodendrocytes and Inflammation
Room: Quandary Peak

Speaker 6 of 7
Claudia Fuchs, University of Bologna, Italy
Short Talk: Loss of CDKL5 Enhances Microglia Activation: Are Neuro-Inflammatory Mechanisms Implicated in the Pathophysiology of CDKL5 Deficiency Disorder?

Thursday, June 20 | 8:30AM - 11:30AM
Oligodendrocytes and Inflammation
Room: Quandary Peak

Speaker 7 of 7
TrangKimberly T. Nguyen, Emory University, USA
Short Talk: Proteomic Analyses Reveal that Glia-Specific and Seizure-Protective Receptors GPR37L1 and GPR37 Regulate S100A Calcium-Binding Protein Expression and Secretion

Thursday, June 20 | 8:30AM - 11:30AM
Drivers of Synaptic Loss in Disease
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 1 of 8
* Clotilde Lagier-Tourenne, Massachusetts General Hospital, USA


Thursday, June 20 | 8:30AM - 11:30AM
Drivers of Synaptic Loss in Disease
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 2 of 8
Paul F. Worley, Johns Hopkins School of Medicine, USA
Immediate Early Genes and Alzheimer’s Disease


Thursday, June 20 | 8:30AM - 11:30AM
Drivers of Synaptic Loss in Disease
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 3 of 8
Beth Stevens, Boston Children's Hospital, Harvard Medical School, USA
Dynamic Microglia States and Functions in Health & Disease


Thursday, June 20 | 8:30AM - 11:30AM
Drivers of Synaptic Loss in Disease
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak


Coffee Break


Thursday, June 20 | 8:30AM - 11:30AM
Drivers of Synaptic Loss in Disease
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 5 of 8
Karen Hsiao Ashe, University of Minnesota, USA
Synaptic and Cognitive Dysfunction from Non-fibrillar Tau


Thursday, June 20 | 8:30AM - 11:30AM
Drivers of Synaptic Loss in Disease
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 6 of 8
Shanthini Sockanathan, Johns Hopkins University School of Medicine, USA
Control of ADAM10 a-Secretase Cleavage of Amyloid Precursor Protein by GDE2-RECK


Thursday, June 20 | 8:30AM - 11:30AM
Drivers of Synaptic Loss in Disease
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 7 of 8
Ryan Douglas Hallam, University of Guelph, Canada
Short Talk: Synuclein Fibrils Inhibit Synaptic Function in Cortical Neurons through Induction of Nitrosative Stress


Thursday, June 20 | 8:30AM - 11:30AM
Drivers of Synaptic Loss in Disease
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 8 of 8
Claire E. Le Pichon, NICHD, National Institutes of Health, USA
Short Talk: Enhancing the Benefits of DLK Inhibition in a Mouse Model of ALS by Restoring an Adaptive Neuronal Response


Thursday, June 20 | 11:30AM - 5:00PM
On Own for Lunch


Thursday, June 20 | 2:30PM - 4:30PM
Workshop 2: Astrocyte-Microglia Crosstalk during Inflammatio
n
Room: Quandary Peak

Speaker 1 of 8
* Blanca Diaz Castro, University of Edinburgh, UK

Thursday, June 20 | 2:30PM - 4:30PM
Workshop 2: Astrocyte-Microglia Crosstalk during Inflammatio
n
Room: Quandary Peak

Speaker 2 of 8
Lilianne Barbar, New York Stem Cell Foundation Research Institute, USA
Developing in vitro Models of Neurodegeneration Based on Human iPSC-Derived Astrocytes

Thursday, June 20 | 2:30PM - 4:30PM
Workshop 2: Astrocyte-Microglia Crosstalk during Inflammatio
n
Room: Quandary Peak

Speaker 3 of 8
Cristina Gutierrez-Vazquez, Harvard Medical School, USA
EphrinB3 Signaling Promotes Pathogenic Activities in Astrocytes during Central Nervous System Inflammation

Thursday, June 20 | 2:30PM - 4:30PM
Workshop 2: Astrocyte-Microglia Crosstalk during Inflammatio
n
Room: Quandary Peak

Speaker 4 of 8
Weikang Cai, Joslin Diabetes Center, USA
Insulin Signaling-Dependent ATP Release from Astrocytes is Important for Dopamine Release and Depressive-Like Behavior

Thursday, June 20 | 2:30PM - 4:30PM
Workshop 2: Astrocyte-Microglia Crosstalk during Inflammatio
n
Room: Quandary Peak

Speaker 5 of 8
Elena Blanco-Suarez, The Salk Institute for Biological Studies, USA
Astrocyte-Secreted Chrdl1 Promotes Synapse Maturation and Limits Synaptic Plasticity through GluA2-AMPAR Increase

Thursday, June 20 | 2:30PM - 4:30PM
Workshop 2: Astrocyte-Microglia Crosstalk during Inflammatio
n
Room: Quandary Peak

Speaker 6 of 8
Martín M. Riccomagno, University of California, Riverside, USA
Novel Combinatorial Approaches to Selectively Target Reactive Astrocytes

Thursday, June 20 | 2:30PM - 4:30PM
Workshop 2: Astrocyte-Microglia Crosstalk during Inflammatio
n
Room: Quandary Peak

Speaker 7 of 8
Kun Leng, University of California, San Francisco, USA
Mapping Pathways Controlling the Reactive State of Astrocytes through CRISPRi Loss-of-Function Screening and Single-Cell RNA-Seq

Thursday, June 20 | 2:30PM - 4:30PM
Workshop 2: Astrocyte-Microglia Crosstalk during Inflammatio
n
Room: Quandary Peak

Speaker 8 of 8
Deepa Jonnalagadda, Sanford Burnham Prebys Medical Discovery Institute, USA
Sphingosine 1-Phosphate Signaling Effects in Immediate-Early Astrocytes (ieAstrocytes)

Thursday, June 20 | 3:00PM - 4:30PM
Workshop 2
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 1 of 8
* Katerina Akassoglou, University of California, San Francisco, USA


Thursday, June 20 | 3:00PM - 4:30PM
Workshop 2
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 2 of 8
Irina Alexandra Leaf, Biogen, USA
Reverse Translational Multimodal Approach to Identify CSF Signatures Associated with Disease Progression in MS


Thursday, June 20 | 3:00PM - 4:30PM
Workshop 2
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 3 of 8
Chelsey J. LeBlang, Boston University School of Medicine, USA
Modulation of the Inflammatory Response by the RNA-binding Protein TIA1 in the P301S Mouse Model of Tauopathy


Thursday, June 20 | 3:00PM - 4:30PM
Workshop 2
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 4 of 8
Yihang Li, Dana-Farber Cancer Institute, USA
SARM1 Interacts with the Bclw/IP3R Pathway in Paclitaxel-Induced Axon Degeneration


Thursday, June 20 | 3:00PM - 4:30PM
Workshop 2
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 5 of 8
Michael A. Lodato, Boston Children's Hospital, USA
Single-Cell, Whole-Genome Sequencing Reveals Mechanisms of DNA Damage and Somatic Mutation in the Human Brain during Aging and in Neurodegeneration


Thursday, June 20 | 3:00PM - 4:30PM
Workshop 2
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 6 of 8
Michaela O. Lunn, Carleton University, Canada
Contribution of Lrrk2 to the Modulation of Host Immunity during Infection


Thursday, June 20 | 3:00PM - 4:30PM
Workshop 2
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 7 of 8
Jing Yang, Peking University, China
Local Degeneration of Catecholaminergic Axons Acts as the Protective Mechanism in Colitis


Thursday, June 20 | 3:00PM - 4:30PM
Workshop 2
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 8 of 8
Samara Reck-Peterson, University of California, San Diego, USA
A Structural and Mechanistic Model for the Regulation of LRRK2’s Interaction with Microtubules


Thursday, June 20 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Thursday, June 20 | 5:00PM - 6:45PM
Hot Topics
Room: Quandary Peak

Speaker 1 of 4
Erik M. Ullian, University of California, San Francisco, USA
Novel Three-Dimensional Astrocyte-Containing Organoids Recapitulate Key Aspects of Human Neurodegenerative Disease

Thursday, June 20 | 5:00PM - 6:45PM
Hot Topics
Room: Quandary Peak

Speaker 2 of 4
* Long-Jun Wu, Mayo Clinic, USA
Neuronal Network Activity Controls Microglial Process Surveillance in Awake Mice via Norepinephrine Signaling

Thursday, June 20 | 5:00PM - 6:45PM
Hot Topics
Room: Quandary Peak

Speaker 3 of 4
* Yi Ren, Florida State University, USA
The Inflammatory Mechanisms Involved in Myelin-Debris-Induced Pathological Changes in Neural Injury

Thursday, June 20 | 5:00PM - 6:45PM
Hot Topics
Room: Quandary Peak

Speaker 4 of 4
Julia A. Kuhn, Genentech, Inc., USA
Short Talk: Sex Differences in Microglial Contributions to Pain

Thursday, June 20 | 5:00PM - 6:45PM
Glial Contributors to Neurodegeneration
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 1 of 5
* Beth Stevens, Boston Children's Hospital, Harvard Medical School, USA


Thursday, June 20 | 5:00PM - 6:45PM
Glial Contributors to Neurodegeneration
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 2 of 5
Mathew M. Blurton-Jones, University of California, Irvine, USA
Development of a Chimeric Model to Study and Manipulate Human Microglia in vivo


Thursday, June 20 | 5:00PM - 6:45PM
Glial Contributors to Neurodegeneration
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 3 of 5
Katerina Akassoglou, University of California, San Francisco, USA
Neurovascular Interactions: Mechanisms, Imaging, Therapeutics


Thursday, June 20 | 5:00PM - 6:45PM
Glial Contributors to Neurodegeneration
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 4 of 5
Sandeep Robert Datta, Harvard Medical School, USA
The MS4A Gene Family in Alzheimer’s Disease


Thursday, June 20 | 5:00PM - 6:45PM
Glial Contributors to Neurodegeneration
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 5 of 5
Anastasia Efthymiou, Icahn School of Medicine at Mount Sinai, USA
Short Talk: Investigating the Effect of the MS4A locus on Alzheimer's Disease Risk


Thursday, June 20 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions
Room: Quandary Peak

Speaker 1 of 1
Vanda A. Lennon, Mayo Clinic, USA

Thursday, June 20 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 1 of 3
Valina L. Dawson, Johns Hopkins University School of Medicine, USA


Thursday, June 20 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 2 of 3
Joseph W. Lewcock, Denali Therapeutics, USA


Thursday, June 20 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions
This session is from Neurodegenerative Diseases
Room: Grays/Longs Peak

Speaker 3 of 3
Fred H. Gage, The Salk Institute for Biological Studies, USA


Thursday, June 20 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Thursday, June 20 | 8:00PM - 11:00PM
Entertainment
Room: Colorado Rockies Ballroom
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, June 20 | 8:00PM - 11:00PM
Cash Bar
Room: Colorado Rockies Ballroom


Friday, June 21 | 10:24AM - 10:24AM
Departure


*Session Chair.