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Web Desc
Intra- and Intercellular Mechanisms of Aging
Organizer(s): Malene Hansen, Johan Auwerx and Heinrich Jasper
Date: February 09 - 13, 2020
Location: Fairmont Hotel Vancouver, Vancouver, BC, Canada
Sponsored by Astellas Pharma Inc. and Cell Research
Summary of Meeting:
Over the past three decades, studies have highlighted numerous cell-autonomous mechanisms that contribute to organismal aging. Specifically, changes in many genes, pathways, biomolecules and organelles have been shown to affect aging in a number of model organisms in a conserved fashion. However, it has become increasingly clear that these intracellular mechanisms are complemented by cell non-autonomous signaling events to influence aging on a tissue and organismal level. Understanding how an initial deregulation of intracellular functions are likely communicated to other cells, tissues, or organs to thereby impact the lifespan and healthspan of the organism will be key to our understanding of aging and age-related diseases. This conference will focus on intra- and intercellular mechanisms of aging, by highlighting current research on key cell-autonomous mechanisms such as DNA, protein and mitochondrial homeostasis, as well as inter-tissue signaling events relevant to aging and age-related diseases, in particular neurodegenerative disorders.
Scholarship Deadline: October 31 2019
Discounted Abstract Deadline: October 31 2019
Abstract Deadline: November 7 2019
Discounted Registration Deadline: December 11 2019
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Astellas Pharma Inc.Cell Research
We gratefully acknowledge additional support for this conference from:
eLife
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Calico

Calico Life Sciences LLC
We gratefully acknowledge the generous grant for this conference provided by:

National Institute on Aging (NIA)
Grant No. 1R13AG064967-01
Funding for this conference was made possible (in part) by 1R13AG064967-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, February 09 | 4:00PM - 8:00PM
Arrival and Registration
Room: British/Columbia Foyer


Sunday, February 09 | 6:00PM - 8:00PM
Welcome Mixer
Room: British/Columbia Foyer
No registration fees are used to fund alcohol served at this function.

Monday, February 10 | 7:30AM - 8:30AM
Breakfast
Room: Columbia Ballroom


Monday, February 10 | 8:00AM - 8:30AM
Poster Setup
Room: Columbia Ballroom


Monday, February 10 | 8:30AM - 7:00PM
Poster Viewing
Room: Columbia Ballroom


Monday, February 10 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: British Ballroom

Speaker 1 of 3
* Malene Hansen, Sanford Burnham Prebys Medical Discovery Institute, USA

Monday, February 10 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: British Ballroom

Speaker 2 of 3
* Johan Auwerx, École Polytechnique Fédérale de Lausanne, Switzerland

Monday, February 10 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: British Ballroom

Speaker 3 of 3
Andrew G. Dillin, University of California, Berkeley, USA
Cell Autonomous and Cell Non-Autonomous Regulation of Proteostasis

Monday, February 10 | 9:30AM - 12:00PM
DNA / Chromatin Homeostasis
Room: British Ballroom

Speaker 1 of 8
* Jason G. Wood, Brown University, USA

Monday, February 10 | 9:30AM - 12:00PM
DNA / Chromatin Homeostasis
Room: British Ballroom

Speaker 2 of 8
* Julia von Maltzahn, Leibniz Institute on Aging, Germany

Monday, February 10 | 9:30AM - 12:00PM
DNA / Chromatin Homeostasis
Room: British Ballroom

Speaker 3 of 8
Peter D. Adams, Sanford Burnham Prebys Medical Discovery Institute, USA
The Dynamic Epigenome – A Challenge to Healthy Aging

Monday, February 10 | 9:30AM - 12:00PM
DNA / Chromatin Homeostasis
Room: British Ballroom


Coffee Break

Monday, February 10 | 9:30AM - 12:00PM
DNA / Chromatin Homeostasis
Room: British Ballroom

Speaker 5 of 8
Joachim Lingner, École Polytechnique Fédérale de Lausanne, Switzerland
Critical Roles of Single Strand Telomere Binding Proteins to Prevent Telomeric DNA Damage, Checkpoint Signaling and Cellular Senescence

Monday, February 10 | 9:30AM - 12:00PM
DNA / Chromatin Homeostasis
Room: British Ballroom

Speaker 6 of 8
Judith Campisi, Buck Institute for Research on Aging, USA
Cellular Senescence and Aging: Cell Autonomous and Non-Autonomous Mechanisms

Monday, February 10 | 9:30AM - 12:00PM
DNA / Chromatin Homeostasis
Room: British Ballroom

Speaker 7 of 8
Abigail K. Brown, Brown University, USA
Short Talk: Long live FOXOs: Transcriptional and Epigenetic Effects of FOXO3 Pioneer-factor Activity in Humans

Monday, February 10 | 9:30AM - 12:00PM
DNA / Chromatin Homeostasis
Room: British Ballroom

Speaker 8 of 8
Siu Sylvia Sylvia Lee, Cornell University, USA
Short Talk: Chromatin Regulation and Longevity in C. elegans


Monday, February 10 | 12:00PM - 12:45PM
Lunch
Room: Columbia Ballroom


Monday, February 10 | 12:00PM - 2:30PM
Poster Session 1
Room: Columbia Ballroom


Monday, February 10 | 3:00PM - 4:30PM
Workshop 1: Emerging Concepts
Room: British Ballroom

Speaker 1 of 8
* Kristopher Burkewitz, Vanderbilt University, USA

Monday, February 10 | 3:00PM - 4:30PM
Workshop 1: Emerging Concepts
Room: British Ballroom

Speaker 2 of 8
* Shuhei Nakamura, Osaka University, Japan

Monday, February 10 | 3:00PM - 4:30PM
Workshop 1: Emerging Concepts
Room: British Ballroom

Speaker 3 of 8
Oliver Hahn, Stanford University, USA
Longitudinal Profiling of Murine Transcriptome in 17 Tissues Uncovers Global Aging Nodes with Organ-Specific Phase and Amplitude

Monday, February 10 | 3:00PM - 4:30PM
Workshop 1: Emerging Concepts
Room: British Ballroom

Speaker 4 of 8
Ann Zenobia Moore, NIA, National Institutes of Health, USA
Addressing the Biomarkers Challenge in Aging Research: The Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT) Study

Monday, February 10 | 3:00PM - 4:30PM
Workshop 1: Emerging Concepts
Room: British Ballroom

Speaker 5 of 8
Erik Ben van den Akker, Leiden University Medical Center, Netherlands
A Nine-Year Longitudinal Study in the Blood of A Supercentenarian Reveals an Extensive Subclonal Architecture with Ongoing Clonal Dynamics and a Functional Thymic Output

Monday, February 10 | 3:00PM - 4:30PM
Workshop 1: Emerging Concepts
Room: British Ballroom

Speaker 6 of 8
Francesco Della Valle, King Abdullah University of Science and Technology, Saudi Arabia
L1 RNA Knockdown Averts Heterochromatin Loss and Premature Ageing Phenotypes

Monday, February 10 | 3:00PM - 4:30PM
Workshop 1: Emerging Concepts
Room: British Ballroom

Speaker 7 of 8
Katrin Kalies, Martin-Luther-University Halle-Wittenberg, Germany
Reversing Endothelial Cell Aging by Partial Reprogramming

Monday, February 10 | 3:00PM - 4:30PM
Workshop 1: Emerging Concepts
Room: British Ballroom

Speaker 8 of 8
Michael A. Bonaguidi, University of Southern California, USA
New Single Cell Tools to Overcome Age-Related Stem Cell Dysfunction

Monday, February 10 | 4:30PM - 5:00PM
Coffee Available
Room: British/Columbia Foyer


Monday, February 10 | 5:00PM - 7:00PM
Vesicle/Membrane Homeostasis
Room: British Ballroom

Speaker 1 of 7
* Ashley E. Webb, Brown University, USA

Monday, February 10 | 5:00PM - 7:00PM
Vesicle/Membrane Homeostasis
Room: British Ballroom

Speaker 2 of 7
* Brian J. North, Creighton University, USA

Monday, February 10 | 5:00PM - 7:00PM
Vesicle/Membrane Homeostasis
Room: British Ballroom

Speaker 3 of 7
Malene Hansen, Sanford Burnham Prebys Medical Discovery Institute, USA
Regulation of Autophagy in Aging and Disease

Monday, February 10 | 5:00PM - 7:00PM
Vesicle/Membrane Homeostasis
Room: British Ballroom

Speaker 4 of 7
Hua Bai, Iowa State University, USA
Peroxisome Aging and Inter-Organ Communication

Monday, February 10 | 5:00PM - 7:00PM
Vesicle/Membrane Homeostasis
Room: British Ballroom

Speaker 5 of 7
Dorota Skowronska-Krawczyk, University of California, San Diego, USA
Aging Membranes – Connecting “Methylation Clock” to the Lipid Metabolism in the Aging Eye

Monday, February 10 | 5:00PM - 7:00PM
Vesicle/Membrane Homeostasis
Room: British Ballroom

Speaker 6 of 7
Shi Quan Wong, Brown University, USA
Short Talk: Neuronal HLH-30/TFEB in Stress and Longevity

Monday, February 10 | 5:00PM - 7:00PM
Vesicle/Membrane Homeostasis
Room: British Ballroom

Speaker 7 of 7
Antonio Gomez-Muñoz, University of the Basque Country, Spain
Short Talk: Regulation of Autophagy and Cell Survival by Ceramide 1-Phosphate

Monday, February 10 | 7:00PM - 7:00PM
On Own for Dinner


Tuesday, February 11 | 7:30AM - 8:30AM
Breakfast
Room: Columbia Ballroom


Tuesday, February 11 | 8:30AM - 11:30AM
Protein Homeostasis
Room: British Ballroom

Speaker 1 of 9
* Claudia Chini, Mayo Clinic, USA

Tuesday, February 11 | 8:30AM - 11:30AM
Protein Homeostasis
Room: British Ballroom

Speaker 2 of 9
* Hua Bai, Iowa State University, USA

Tuesday, February 11 | 8:30AM - 11:30AM
Protein Homeostasis
Room: British Ballroom

Speaker 3 of 9
Judith Frydman, Stanford University, USA
Proteostasis Disfunction and Aggregate Management: Implications for Aging and Neurodegenerative Disease

Tuesday, February 11 | 8:30AM - 11:30AM
Protein Homeostasis
Room: British Ballroom

Speaker 4 of 9
Richard I. Morimoto, Northwestern University, USA
Cell Non-Autonomous Regulation of Organismal Proteostasis

Tuesday, February 11 | 8:30AM - 11:30AM
Protein Homeostasis
Room: British Ballroom


Coffee Break

Tuesday, February 11 | 8:30AM - 11:30AM
Protein Homeostasis
Room: British Ballroom

Speaker 6 of 9
Benoit Lehallier, Stanford University, USA
Short Talk: Undulating Changes in Human Plasma Proteome Profiles Across the Lifespan are Linked to Disease

Tuesday, February 11 | 8:30AM - 11:30AM
Protein Homeostasis
Room: British Ballroom

Speaker 7 of 9
Ashley E. Frakes, University of California, Berkeley, USA
Short Talk: Four Glial Cells Regulate ER Stress Resistance and Longevity via Neuropeptide Signaling

Tuesday, February 11 | 8:30AM - 11:30AM
Protein Homeostasis
Room: British Ballroom

Speaker 8 of 9
Ao-Lin Allen Hsu, University of Michigan, USA
Short Talk: HSB-1/HSF-1 Pathway Modulates Histone H4 in Mitochondria to Control mtDNA Transcription and Longevity

Tuesday, February 11 | 8:30AM - 11:30AM
Protein Homeostasis
Room: British Ballroom

Speaker 9 of 9
Alessandro Ori, Leibniz Institute on Aging, Germany
Short Talk: Reduced Proteasome Activity in the Aging Brain Results in Ribosome Stoichiometry Loss and Aggregation

Tuesday, February 11 | 11:30AM - 5:00PM
On Own for Lunch


Tuesday, February 11 | 11:30AM - 1:00PM
Poster Setup
Room: Columbia Ballroom


Tuesday, February 11 | 1:00PM - 10:00PM
Poster Viewing
Room: Columbia Ballroom


Tuesday, February 11 | 2:30PM - 4:30PM
Workshop 2: Mentoring - Career Roundtable
Room: British/Columbia Ballroom

Speaker 1 of 11
* Malene Hansen, Sanford Burnham Prebys Medical Discovery Institute, USA

Tuesday, February 11 | 2:30PM - 4:30PM
Workshop 2: Mentoring - Career Roundtable
Room: British/Columbia Ballroom

Speaker 2 of 11
Anna Kriebs, Nature Communications, Germany

Tuesday, February 11 | 2:30PM - 4:30PM
Workshop 2: Mentoring - Career Roundtable
Room: British/Columbia Ballroom

Speaker 3 of 11
Julie Sollier, Developmental Cell, USA

Tuesday, February 11 | 2:30PM - 4:30PM
Workshop 2: Mentoring - Career Roundtable
Room: British/Columbia Ballroom

Speaker 4 of 11
Felipe Sierra, NIA, National Institutes of Health, USA

Tuesday, February 11 | 2:30PM - 4:30PM
Workshop 2: Mentoring - Career Roundtable
Room: British/Columbia Ballroom

Speaker 5 of 11
Tracy Rankin, NIDDK, National Institutes of Health, USA

Tuesday, February 11 | 2:30PM - 4:30PM
Workshop 2: Mentoring - Career Roundtable
Room: British/Columbia Ballroom

Speaker 6 of 11
Ashley E. Webb, Brown University, USA

Tuesday, February 11 | 2:30PM - 4:30PM
Workshop 2: Mentoring - Career Roundtable
Room: British/Columbia Ballroom

Speaker 7 of 11
Dario Riccardo Valenzano, Max-Planck Institute for Biology of Ageing, Germany

Tuesday, February 11 | 2:30PM - 4:30PM
Workshop 2: Mentoring - Career Roundtable
Room: British/Columbia Ballroom

Speaker 8 of 11
Johan Auwerx, École Polytechnique Fédérale de Lausanne, Switzerland

Tuesday, February 11 | 2:30PM - 4:30PM
Workshop 2: Mentoring - Career Roundtable
Room: British/Columbia Ballroom

Speaker 9 of 11
Heinrich Jasper, Genentech, Inc., USA

Tuesday, February 11 | 2:30PM - 4:30PM
Workshop 2: Mentoring - Career Roundtable
Room: British/Columbia Ballroom

Speaker 10 of 11
Chee-Yeun Chung, Yumanity Therapeutics, USA

Tuesday, February 11 | 2:30PM - 4:30PM
Workshop 2: Mentoring - Career Roundtable
Room: British/Columbia Ballroom

Speaker 11 of 11
Laurent Taupenot, CSR, National Institutes of Health, USA

Tuesday, February 11 | 4:30PM - 5:00PM
Coffee Available
Room: British/Columbia Foyer


Tuesday, February 11 | 5:00PM - 7:00PM
Mitochondrial Homeostasis
Room: British Ballroom

Speaker 1 of 7
* Maria Ermolaeva, Leibniz Institute on Aging, Germany

Tuesday, February 11 | 5:00PM - 7:00PM
Mitochondrial Homeostasis
Room: British Ballroom

Speaker 2 of 7
* Mark McCormick, University of New Mexico, USA

Tuesday, February 11 | 5:00PM - 7:00PM
Mitochondrial Homeostasis
Room: British Ballroom

Speaker 3 of 7
Johan Auwerx, École Polytechnique Fédérale de Lausanne, Switzerland
A Conserved Role of CBP/p300 in Mitochondrial Stress Response and Longevity

Tuesday, February 11 | 5:00PM - 7:00PM
Mitochondrial Homeostasis
Room: British Ballroom

Speaker 4 of 7
David Walker, University of California, Los Angeles, USA
Role of Mitophagy in Drosophila Aging

Tuesday, February 11 | 5:00PM - 7:00PM
Mitochondrial Homeostasis
Room: British Ballroom

Speaker 5 of 7
Cole M. Haynes, University of Massachusetts Medical School, USA
Scaling Mitochondrial Network Expansion with Cell Growth or Recovery

Tuesday, February 11 | 5:00PM - 7:00PM
Mitochondrial Homeostasis
Room: British Ballroom

Speaker 6 of 7
Amanda J. Audesse, Brown University, USA
Short Talk: Elucidating the Function of Mitophagy in the Maintenance of Metabolic Stability Throughout Neural Stem Cell Aging

Tuesday, February 11 | 5:00PM - 7:00PM
Mitochondrial Homeostasis
Room: British Ballroom

Speaker 7 of 7
Kristopher Burkewitz, Vanderbilt University, USA
Short Talk: Exploring the Roles of ER-Mitochondrial Calcium Coordination in Aging

Tuesday, February 11 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Columbia Ballroom
No registration fees are used to fund alcohol served at this function.

Tuesday, February 11 | 7:30PM - 10:00PM
Poster Session 2
Room: Columbia Ballroom


Wednesday, February 12 | 7:30AM - 8:30AM
Breakfast
Room: Columbia Ballroom


Wednesday, February 12 | 8:30AM - 11:45AM
Inter-Tissue Signaling
Room: British Ballroom

Speaker 1 of 10
* Dorota Skowronska-Krawczyk, University of California, San Diego, USA

Wednesday, February 12 | 8:30AM - 11:45AM
Inter-Tissue Signaling
Room: British Ballroom

Speaker 2 of 10
* Louis R. Lapierre, Brown University, USA

Wednesday, February 12 | 8:30AM - 11:45AM
Inter-Tissue Signaling
Room: British Ballroom

Speaker 3 of 10
William B. Mair, Harvard School of Public Health, USA
Metabolic Communication and Longevity

Wednesday, February 12 | 8:30AM - 11:45AM
Inter-Tissue Signaling
Room: British Ballroom

Speaker 4 of 10
Coleen T. Murphy, Princeton University, USA
CREB and TGF-beta Non-Autonomously Regulate Reproductive Aging through Hedgehog/Patched Signaling

Wednesday, February 12 | 8:30AM - 11:45AM
Inter-Tissue Signaling
Room: British Ballroom


Coffee Break

Wednesday, February 12 | 8:30AM - 11:45AM
Inter-Tissue Signaling
Room: British Ballroom

Speaker 6 of 10
Fabio Demontis, St. Jude Children's Research Hospital, USA
Systemic Nutrient Signaling via Myokines

Wednesday, February 12 | 8:30AM - 11:45AM
Inter-Tissue Signaling
Room: British Ballroom

Speaker 7 of 10
Minho M. Shong, Chungnam National University School of Medicine, South Korea
Role of Mammalian Mitokine GDF15 in Mammalian Metabolism

Wednesday, February 12 | 8:30AM - 11:45AM
Inter-Tissue Signaling
Room: British Ballroom

Speaker 8 of 10
Alana M. Horowitz, University of California, San Francisco, USA
Short Talk: Circulating Blood Factors Confer the Rejuvenating Benefits of Exercise on the Aged Brain

Wednesday, February 12 | 8:30AM - 11:45AM
Inter-Tissue Signaling
Room: British Ballroom

Speaker 9 of 10
Mikolaj Ogrodnik, Mayo Clinic, USA
Short Talk: Relationship Between Lipid Metabolism and Inflammation of Senescent Cells and Its Impact on Obesity- and Aging-Related Brain Dysfunctions

Wednesday, February 12 | 8:30AM - 11:45AM
Inter-Tissue Signaling
Room: British Ballroom

Speaker 10 of 10
Chris Morrow, University of Wisconsin - Madison, USA
Short Talk: Aggresome-Mediated Quiescent Neural Stem Cell Activation

Wednesday, February 12 | 11:45AM - 5:00PM
On Own for Lunch


Wednesday, February 12 | 4:30PM - 5:00PM
Coffee Available
Room: British/Columbia Foyer


Wednesday, February 12 | 5:00PM - 7:15PM
Stem Cells
Room: British Ballroom

Speaker 1 of 8
* Saul A. Villeda, University of California, San Francisco, USA

Wednesday, February 12 | 5:00PM - 7:15PM
Stem Cells
Room: British Ballroom

Speaker 2 of 8
* Fabio Demontis, St. Jude Children's Research Hospital, USA

Wednesday, February 12 | 5:00PM - 7:15PM
Stem Cells
Room: British Ballroom

Speaker 3 of 8
Heinrich Jasper, Genentech, Inc., USA
Intestinal Stem Cells and Aging in Flies and Beyond

Wednesday, February 12 | 5:00PM - 7:15PM
Stem Cells
Room: British Ballroom

Speaker 4 of 8
Pekka Katajisto, University of Helsinki, Finland
Role of Stem Cell Niche in Intestinal Aging

Wednesday, February 12 | 5:00PM - 7:15PM
Stem Cells
Room: British Ballroom

Speaker 5 of 8
Pura Munoz Munoz Canoves, Universitat Pompeu Fabra, Spain
Identification of an Age-Resistant Quiescent Muscle Stem-Cell State

Wednesday, February 12 | 5:00PM - 7:15PM
Stem Cells
Room: British Ballroom

Speaker 6 of 8
Indranil Sinha, Brigham and Women's Hospital, USA
Short Talk: Aging-Associated Loss of ARNT Limits Skeletal Muscle Regeneration

Wednesday, February 12 | 5:00PM - 7:15PM
Stem Cells
Room: British Ballroom

Speaker 7 of 8
Daniel E. Colquhoun, Monash University, Australia
Short Talk: Hmga1a Suppresses mTOR Signaling Following Activation to Allow for Lifelong Maintenance of Neural Stem/Progenitor Cells

Wednesday, February 12 | 5:00PM - 7:15PM
Stem Cells
Room: British Ballroom

Speaker 8 of 8
Helen Tauc, Genentech, Inc., USA
Short Talk: Identity Crisis? A Story about Aging Drosophila Intestinal Stem Cells

Wednesday, February 12 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Columbia Ballroom
No registration fees are used to fund alcohol served at this function.

Thursday, February 13 | 7:30AM - 8:30AM
Breakfast
Room: Columbia Ballroom


Thursday, February 13 | 8:30AM - 12:00PM
Metabolism
Room: British Ballroom

Speaker 1 of 10
* Erik Ben van den Akker, Leiden University Medical Center, Netherlands

Thursday, February 13 | 8:30AM - 12:00PM
Metabolism
Room: British Ballroom

Speaker 2 of 10
Meng C. Wang, Baylor College of Medicine/HHMI, USA
Metabolite Signals in Longevity Regulation

Thursday, February 13 | 8:30AM - 12:00PM
Metabolism
Room: British Ballroom

Speaker 3 of 10
Dario Riccardo Valenzano, Max-Planck Institute for Biology of Ageing, Germany
Systemic Regulation of Aging via the Gut Microbiota

Thursday, February 13 | 8:30AM - 12:00PM
Metabolism
Room: British Ballroom


Coffee Break

Thursday, February 13 | 8:30AM - 12:00PM
Metabolism
Room: British Ballroom

Speaker 5 of 10
Anne Brunet, Stanford University, USA
Identifying Mechanisms of Brain Aging

Thursday, February 13 | 8:30AM - 12:00PM
Metabolism
Room: British Ballroom

Speaker 6 of 10
P. Eline Slagboom, Leiden University, Netherlands
Hall Marks of Human Aging in the Molecular Profiles of Intervention and Cohort Studies

Thursday, February 13 | 8:30AM - 12:00PM
Metabolism
Room: British Ballroom

Speaker 7 of 10
Hillary Miller, University of Michigan, USA
Short Talk: Serotonin Signaling in Food Perception and Dietary Restriction

Thursday, February 13 | 8:30AM - 12:00PM
Metabolism
Room: British Ballroom

Speaker 8 of 10
Eduardo Nunes Chini, Mayo Clinic, USA
Short Talk: The Ecto-Enzyme CD38 Links Cellular Senescence and NAD Metabolism During Aging

Thursday, February 13 | 8:30AM - 12:00PM
Metabolism
Room: British Ballroom

Speaker 9 of 10
Maria Ermolaeva, Leibniz Institute on Aging, Germany
Short Talk: The Longevity Benefits of Metformin Are Age and Gender Dependent

Thursday, February 13 | 8:30AM - 12:00PM
Metabolism
Room: British Ballroom

Speaker 10 of 10
Priyanka Narayan, Massachusetts Institute of Technology, USA
Short Talk: Identifying and Reversing APOE4-Induced Cellular Pathologies

Thursday, February 13 | 12:00PM - 5:00PM
On Own for Lunch


Thursday, February 13 | 4:30PM - 5:00PM
Coffee Available
Room: British/Columbia Foyer


Thursday, February 13 | 5:00PM - 7:00PM
Neurodegenerative Diseases
Room: British Ballroom

Speaker 1 of 7
* Chia-Chen Lu, Fu Jen Catholic University, Taiwan

Thursday, February 13 | 5:00PM - 7:00PM
Neurodegenerative Diseases
Room: British Ballroom

Speaker 2 of 7
* Michael A. Bonaguidi, University of Southern California, USA

Thursday, February 13 | 5:00PM - 7:00PM
Neurodegenerative Diseases
Room: British Ballroom

Speaker 3 of 7
Saul A. Villeda, University of California, San Francisco, USA
Mechanisms of Brain Aging and Rejuvenation

Thursday, February 13 | 5:00PM - 7:00PM
Neurodegenerative Diseases
Room: British Ballroom

Speaker 4 of 7
Chee-Yeun Chung, Yumanity Therapeutics, USA
From Yeast to Neurons to Patients: A Novel Drug Discovery Platform for Neurodegenerative Diseases

Thursday, February 13 | 5:00PM - 7:00PM
Neurodegenerative Diseases
Room: British Ballroom

Speaker 5 of 7
Ana Maria Cuervo, Albert Einstein College of Medicine, USA
Role of Chaperone-Mediated Autophagy in Neurodegeneration and Aging

Thursday, February 13 | 5:00PM - 7:00PM
Neurodegenerative Diseases
Room: British Ballroom

Speaker 6 of 7
Kathryn A. Jewett, University of Washington, USA
Short Talk: Non-Cell Autonomous Mechanisms Regulating Protein Aggregation in a Drosophila Model of Parkinson’s Disease

Thursday, February 13 | 5:00PM - 7:00PM
Neurodegenerative Diseases
Room: British Ballroom

Speaker 7 of 7
Kaspar Russ, Lundbeck and Lund University, Denmark
Short Talk: TNFa and a-Synuclein Assemblies Differently Regulate Human Astrocyte Reactivity: Implications for Parkinson’s Disease

Thursday, February 13 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions
Room: British Ballroom

Speaker 1 of 1
Heinrich Jasper, Genentech, Inc., USA

Thursday, February 13 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Columbia Ballroom
No registration fees are used to fund alcohol served at this function.

Thursday, February 13 | 8:00PM - 11:00PM
Entertainment
Room: Columbia Ballroom
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Friday, February 14 | 10:24AM - 10:24AM
Departure


*Session Chair.