Intra- and Intercellular Mechanisms of Aging

Organizer(s): Malene Hansen, Johan Auwerx and Heinrich Jasper

Sponsored by Astellas Pharma Inc. and Cell Research

Summary of Meeting:

Over the past three decades, studies have highlighted numerous cell-autonomous mechanisms that contribute to organismal aging. Specifically, changes in many genes, pathways, biomolecules and organelles have been shown to affect aging in a number of model organisms in a conserved fashion. However, it has become increasingly clear that these intracellular mechanisms are complemented by cell non-autonomous signaling events to influence aging on a tissue and organismal level. Understanding how an initial deregulation of intracellular functions are likely communicated to other cells, tissues, or organs to thereby impact the lifespan and healthspan of the organism will be key to our understanding of aging and age-related diseases. This conference will focus on intra- and intercellular mechanisms of aging, by highlighting current research on key cell-autonomous mechanisms such as DNA, protein and mitochondrial homeostasis, as well as inter-tissue signaling events relevant to aging and age-related diseases, in particular neurodegenerative disorders.

Scholarship Deadline: October 31 2019

Discounted Abstract Deadline: October 31 2019

Abstract Deadline: November 7 2019

Discounted Registration Deadline: December 11 2019

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Calico

Calico Life Sciences LLC

We gratefully acknowledge the generous grant for this conference provided by:

National Institute on Aging (NIA)
Grant No. 1R13AG064967-01
Funding for this conference was made possible (in part) by 1R13AG064967-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

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