Web Desc
Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats
Organizer(s): Rino Rappuoli, Lynda M. Stuart and Federica Sallusto
Date: June 15 - 16, 2020
Location: Virtual at your computer.  Recorded presentation content is available On Demand.
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Join us for this landmark virtual event, with support from The Bill & Melinda Gates Foundation, The National Institute of Allergy and Infectious Diseases (NIAID), and Menarini International Foundation.
 
Summary of Meeting:
As the world faces the greatest global pandemic of our lifetimes, the critical importance of vaccine development has come to the forefront of scientific and public audiences alike. Over the course of history, vaccination has enabled us to conquer devastating diseases from measles to smallpox, but new challenges arise when addressing anemerging pandemic in real time.This virtual meeting will assemble the world’s leading vaccinology and global health experts to present the latest advances in vaccine design and development. Finally, this virtual conference will discuss how to best apply these strategies in the context of the current pandemic. The field of vaccinology has made great leaps in recent years, providing novel technologies and approaches that can be leveraged to our advantage against the novel coronavirus, COVID-19. Incredible advances in science and technology now make it technically possible to develop vaccines against many new targets. Meanwhile,innovative approaches to vaccine development?are tackling challenges of emerging infections and implementation in low-income countries. These advances, among many others, will guide the way towards a safe and effective COVID-19 vaccine. Additionally, these new scientific advances will set the stage for success against this pandemic,as vaccinologists race against the ever-rising global death toll. This virtual meeting program will cover many important facets of vaccine science, technology and strategy, including: - transformative new technologies, including structure-based design, adjuvants, nucleic acid vaccines (especially RNA), viral vectors, systems biology, and controlled human infections - scientific underpinnings of new vaccinology strategies, including advances in the fields of human immunology, genomics, synthetic biology, molecular structure of antigens and antigen-antibody complexes, germinal centers, and microbiome - multidisciplinary technologies and strategies, including efforts of Coalition for Epidemic Preparedness Innovations (CEPI), Bill & Melinda Gates Foundation and Wellcome Trust, which will change the way vaccines are developed
For important information on the coronavirus, please click here
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
BioLegend, Inc.GlaxoSmithKline BiologicalsModerna
We gratefully acknowledge additional support from these exhibitors at this conference:
TriLink BioTechnologies, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI150086-01
Funding for this conference was made possible (in part) by 1R13AI150086-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Monday, June 15 | 12:00AM - 11:59PM
Posters


Monday, June 15 | 9:00AM - 9:10AM
Introduction

Speaker 1 of 2
Deborah L. Johnson, Keystone Symposia on Molecular and Cellular Biology, USA

Monday, June 15 | 9:00AM - 9:10AM
Introduction

Speaker 2 of 2
Rino Rappuoli, GlaxoSmithKline Vaccines, Italy

Monday, June 15 | 9:10AM - 9:40AM
Keynote Address

Speaker 1 of 1
Anthony S. Fauci, NIAID, National Institutes of Health, USA
Transforming Vaccinology: Pandemic Preparedness and the Response to COVID-19

Monday, June 15 | 9:40AM - 10:35AM
Structure-Based Antigen Design

Speaker 1 of 2
Barney S. Graham, NIAID, National Institutes of Health, USA
Immunogen Design Strategies for COVID-19, RSV, and Other Enveloped Viruses

Monday, June 15 | 9:40AM - 10:35AM
Structure-Based Antigen Design

Speaker 2 of 2
* Neil P. King, University of Washington, USA
Structure-Based Design of Novel Nanoparticle Vaccine Platforms

Monday, June 15 | 10:35AM - 11:35AM
Antigen Presentation and Delivery

Speaker 1 of 3
* Neil P. King, University of Washington, USA

Monday, June 15 | 10:35AM - 11:35AM
Antigen Presentation and Delivery

Speaker 2 of 3
Gabriel D. Victora, Rockefeller University, USA
Clonal Dynamics of Germinal Centers in the Steady-State Gut

Monday, June 15 | 10:35AM - 11:35AM
Antigen Presentation and Delivery

Speaker 3 of 3
Robert A. Seder, NIAID, National Institutes of Health, USA
IV Vaccination: A Paradigm for Inducing Tissue Resident T Cells Against TB and Malaria

Monday, June 15 | 11:35AM - 12:30PM
Therapeutic Vaccines

Speaker 1 of 3
* Mariagrazia Pizza, GlaxoSmithKline Vaccines, Italy

Monday, June 15 | 11:35AM - 12:30PM
Therapeutic Vaccines

Speaker 2 of 3
Catherine J. Wu, Dana-Farber Cancer Institute, USA
Vaccines Against Tumor Neoantigens

Monday, June 15 | 11:35AM - 12:30PM
Therapeutic Vaccines

Speaker 3 of 3
Ulrike Protzer, Technische Universität München, Germany
Therapeutic HBV Vaccines

Monday, June 15 | 12:30PM - 1:30PM
Human Monoclonal Antibodies

Speaker 1 of 3
* Mariagrazia Pizza, GlaxoSmithKline Vaccines, Italy

Monday, June 15 | 12:30PM - 1:30PM
Human Monoclonal Antibodies

Speaker 2 of 3
Hedda Wardemann, German Cancer Research Center, Germany
Dissecting Antibody Responses to Plasmodium Falciparum Circumsporozoite Protein for the Development of a Malaria Vaccine

Monday, June 15 | 12:30PM - 1:30PM
Human Monoclonal Antibodies

Speaker 3 of 3
Antonio Lanzavecchia, Institute for Research in Biomedicine, Switzerland
Human Monoclonals for COVID-19 Passive Immunization and Antigen Discovery

Monday, June 15 | 1:30PM - 1:30PM
Closing Remarks


Tuesday, June 16 | 9:00AM - 9:05AM
Opening Remarks

Speaker 1 of 1
Lynda M. Stuart, Bill & Melinda Gates Foundation, USA

Tuesday, June 16 | 9:05AM - 9:50AM
RNA Vaccines

Speaker 1 of 3
* Bali Pulendran, Stanford University School of Medicine, USA

Tuesday, June 16 | 9:05AM - 9:50AM
RNA Vaccines

Speaker 2 of 3
Christine Shaw, Moderna, USA
mRNA Vaccines Against Viruses

Tuesday, June 16 | 9:05AM - 9:50AM
RNA Vaccines

Speaker 3 of 3
Robin Shattock, Imperial College London, UK
Development of a COVID-19 Self-Amplifying RNA Vaccine

Tuesday, June 16 | 9:50AM - 10:50AM
Systems Biology

Speaker 1 of 2
Galit Alter, MIT and Harvard University, USA
Applying Systems Serology to Define Humoral Correlates of Immunity Against Malaria

Tuesday, June 16 | 9:50AM - 10:50AM
Systems Biology

Speaker 2 of 2
* Bali Pulendran, Stanford University School of Medicine, USA
Human Immunity to SARS-CoV-2

Tuesday, June 16 | 10:50AM - 11:40AM
Immune Response

Speaker 1 of 3
* Lynda M. Stuart, Bill & Melinda Gates Foundation, USA

Tuesday, June 16 | 10:50AM - 11:40AM
Immune Response

Speaker 2 of 3
Alessandro Sette, La Jolla Institute for Immunology, USA
SARS CoV2 Specific T Cell Responses in Exposed and Non-Exposed Subjects

Tuesday, June 16 | 10:50AM - 11:40AM
Immune Response

Speaker 3 of 3
Yasmine Belkaid, NIAID, National Institutes of Health, USA
Microbiota Control of Tissue Immunity

Tuesday, June 16 | 11:40AM - 1:00PM
E-Panel: Facing COVID-19 and Other Emerging Infections

Speaker 1 of 4
Rino Rappuoli, GlaxoSmithKline Vaccines, Italy

Tuesday, June 16 | 11:40AM - 1:00PM
E-Panel: Facing COVID-19 and Other Emerging Infections

Speaker 2 of 4
Richard Hatchett, Coalition for Epidemic Preparedness Innovations, CEPI, UK

Tuesday, June 16 | 11:40AM - 1:00PM
E-Panel: Facing COVID-19 and Other Emerging Infections

Speaker 3 of 4
George Fu Gao, Institute of Microbiology, Chinese Academy of Sciences, China

Tuesday, June 16 | 11:40AM - 1:00PM
E-Panel: Facing COVID-19 and Other Emerging Infections

Speaker 4 of 4
Lynda M. Stuart, Bill & Melinda Gates Foundation, USA

Tuesday, June 16 | 1:00PM - 1:15PM
Closing Remarks