This meeting took place in the past. Here is a list of meetings that are related:
Web Desc
The Malaria Endgame: Innovation in Therapeutics, Vector Control and Public Health Tools
Organizer(s): Thierry Diagana, Philip Welkhoff and Flaminia Catteruccia
Date: October 30 - November 02, 2019
Location: Hilton Addis Ababa, Addis Ababa, Ethiopia
Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation
Summary of Meeting:
Malaria is most prevalent in the tropical belt and many malaria endemic countries have now engaged in elimination programs. However, we are facing a public health crisis because we have lost many of the public health tools that enabled the progress we have made to date. Many drugs are useless in most areas and resistance is threatening even artemisinin-based combination therapy (ACT). Diagnostics, bed-nets and insecticides are also losing their effectiveness and the Plasmodium vivax (P. vivax) parasite is finding new ways to transmit in Duffy negative patients. At the same time, there are multiple emerging threats such as artemisinin drug resistance, the rise of P. vivax malaria prevalence, and the discovery of the parasite Plasmodium knowlesi (P. knowlesi) in humans. However, there are some interesting developments such as deploying older suboptimal drugs in new, innovative and targeted control approaches like seasonal malaria chemoprevention (SMC) or intermittent preventive treatment of pregnant women/ infants (PTi/p). There are new drugs on the horizon that have pharmacological properties compatible with single dose cures and could prove to be powerful tools in the fight against malaria. For example, mass drug administration has demonstrated substantial impact as an intervention for Plasmodium elimination. By learning from recent successes in malaria elimination, epidemiological models of malaria transmission can be updated, and the impact of new interventions will critically inform the malaria endgame strategy. The conference is organized around three themes: defeating resistance (both to drugs and to insecticides), leveraging data science to better understand disease transmission and innovation in vector control strategies. This program will assess the current threats and gaps in our malaria armamentarium to enable malaria elimination and discuss the emerging innovative approaches for antimalarial drug discovery and development.
Global Health Travel Award Deadline: June 11 2019
Scholarship Deadline: July 9 2019
Discounted Abstract Deadline: July 9 2019
Abstract Deadline: July 30 2019
Discounted Registration Deadline: August 29 2019
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Bill & Melinda Gates Foundation
We gratefully acknowledge additional support from these exhibitors at this conference:
inqaba biotec
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Wednesday, October 30 | 10:00AM - 8:00PM
Arrival and Registration
Room: Ballroom Foyer - Hilton Addis Ababa


Wednesday, October 30 | 12:30PM - 2:30PM
Welcome Mixer
Room: Ballroom Foyer - Hilton Addis Ababa


Wednesday, October 30 | 4:00PM - 6:00PM
Joint Keynote Session with Grand Challenges
Room: Nelson Mandela Hall - African Union
Where We Go Next: African Leadership for African Innovation

Welcome Remarks


Moussa Faki Mahamat, Chairperson, African Union Commission


Keynote Remarks

Tedros Adhanom Ghebreyesus, Director-General, World Health Organization

Keynote Remarks

Ethiopia Government Representative (TBC)

Keynote Remarks

Senegal Government Representative (TBC)

Keynote Remarks

Burkina Faso Government Representative (TBC)


Spotlight Talk

Segenet Kelemu, Director General & CEO, International Centre of Insect Physiology and Ecology


Conversation and Q&A: Gene Drive for Malaria Elimination

Moderator: Philip Welkhoff, Director, Malaria, Bill & Melinda Gates Foundation

Panelists:

Léonie Claudine Lougué, Minister of Health, Burkina Faso

Yaye Kène-Gassama Dia, Co-chair, African Union High Level Panel on Emerging Technologies

Jerome Singh, Head of Ethics and Law, CAPRISA, University of KwaZulu-Natal

Abdoulaye Diabaté, Research Lead, Target Malaria


Spotlight Talk

Faith Osier, Research Lead, KEMRI-Wellcome Trust Research Programme, Kenya


Closing Conversation

Moderator: Trevor Mundel, President, Global Health, Bill & Melinda Gates Foundation

Panelists:

Balram Bhargava, Director General, Indian Council of Medical Research (Invited)

Tedros Adhanom Ghebreyesus, Director-General, World Health Organization

Renu Swarup, Secretary, Department of Biotechnology Ministry of Science & Technology, India

Wednesday, October 30 | 6:00PM - 7:45PM
Networking and Welcome Mixer with Grand Challenges
Room: African Union


Thursday, October 31 | 8:00AM - 9:00AM
Poster Setup
Room: Ballroom I&II


Thursday, October 31 | 9:00AM - 5:30PM
Poster Viewing
Room: Ballroom I&II


Thursday, October 31 | 9:00AM - 10:00AM
Welcome and Keynote Address
Room: Ballroom I&II

Speaker 1 of 4
* Thierry T. Diagana, Novartis Institute for Tropical Diseases, USA

Thursday, October 31 | 9:00AM - 10:00AM
Welcome and Keynote Address
Room: Ballroom I&II

Speaker 2 of 4
* Philip Welkhoff, Bill & Melinda Gates Foundation, USA

Thursday, October 31 | 9:00AM - 10:00AM
Welcome and Keynote Address
Room: Ballroom I&II

Speaker 3 of 4
* Flaminia Catteruccia, Harvard T.H. Chan School of Public Health, USA

Thursday, October 31 | 9:00AM - 10:00AM
Welcome and Keynote Address
Room: Ballroom I&II

Speaker 4 of 4
Stephanie L. James, Foundation for the National Institutes of Health, USA
The Pathway for Development of a Genetic Biocontrol Tool to Prevent Malaria Transmission

Thursday, October 31 | 10:00AM - 12:15PM
Defeating Resistance I
Room: Ballroom I&II

Speaker 1 of 6
* Thierry T. Diagana, Novartis Institute for Tropical Diseases, USA

Thursday, October 31 | 10:00AM - 12:15PM
Defeating Resistance I
Room: Ballroom I&II

Speaker 2 of 6
Chanaki Amaratunga, Faculty of Tropical Medicine, Mahidol University, Thailand
Triple Artemisinin Combination Therapies: A New Paradigm for the Treatment of Malaria?

Thursday, October 31 | 10:00AM - 12:15PM
Defeating Resistance I
Room: Ballroom I&II


Coffee Break

Thursday, October 31 | 10:00AM - 12:15PM
Defeating Resistance I
Room: Ballroom I&II

Speaker 4 of 6
Wiweka Kaszubska, Medicines for Malaria Venture, Switzerland
Building a Global Portfolio of Drugs to Anticipate Malaria Drug Resistance

Thursday, October 31 | 10:00AM - 12:15PM
Defeating Resistance I
Room: Ballroom I&II

Speaker 5 of 6
Elizabeth A. Winzeler, University of California, San Diego, USA
The Malaria Drug Accelerator and the Search for Next-Generation Medicines for Malaria

Thursday, October 31 | 10:00AM - 12:15PM
Defeating Resistance I
Room: Ballroom I&II

Speaker 6 of 6
Geoffrey Ian McFadden, University of Melbourne, Australia
Short Talk: Can We Build a Genetic Trap for Drug Resistant Malaria Parasites?

Thursday, October 31 | 12:15PM - 1:30PM
Lunch
Room: Rose Garden


Thursday, October 31 | 1:30PM - 3:30PM
Poster Session 1
Room: Ballroom I&II


Thursday, October 31 | 3:30PM - 4:00PM
Coffee Available
Room: Ballroom Foyer


Thursday, October 31 | 4:00PM - 6:00PM
Defeating Resistance II
Room: Ballroom I&II

Speaker 1 of 6
* Nancy O. Quashie, Noguchi Memorial Institute for Medical Research, Ghana

Thursday, October 31 | 4:00PM - 6:00PM
Defeating Resistance II
Room: Ballroom I&II

Speaker 2 of 6
Manu Prakash, Stanford University, USA
Short Talk: Octopi: Open Configurable High-Throughput Imaging Platform for Malaria Diagnosis in the Field


Thursday, October 31 | 4:00PM - 6:00PM
Defeating Resistance II
Room: Ballroom I&II

Speaker 3 of 6
Abdoulaye Djimde, University of Science, Techniques and Technologies, Mali
Is Artemisinin Resistance Coming to Sub-Saharan Africa?

Thursday, October 31 | 4:00PM - 6:00PM
Defeating Resistance II
Room: Ballroom I&II

Speaker 4 of 6
Gordon A. Awandare, University of Ghana, Ghana
Keeping an Eye on the Non-Falciparum Plasmodium Species

Thursday, October 31 | 4:00PM - 6:00PM
Defeating Resistance II
Room: Ballroom I&II

Speaker 5 of 6
Charles Wondji, Liverpool School of Tropical Medicine, UK
Molecular Genetics of Insecticide Resistance in Malaria Vectors

Thursday, October 31 | 4:00PM - 6:00PM
Defeating Resistance II
Room: Ballroom I&II

Speaker 6 of 6
Lemu Golassa, Addis Ababa University, Ethiopia
Short Talk: Conventional Malaria Diagnostic Tools Neglect a Substantial Number of Low Density Asymptomatic Infections: Is Malaria Elimination Feasible in the Absence of New Tools?

Friday, November 01 | 9:00AM - 12:00PM
Leveraging Data Science to Defeat Malaria I
Room: Ballroom I&II

Speaker 1 of 9
* Asnakew Yeshiwondim, PATH Malaria Control and Elimination Partnership in Africa, Ethiopia

Friday, November 01 | 9:00AM - 12:00PM
Leveraging Data Science to Defeat Malaria I
Room: Ballroom I&II

Speaker 2 of 9
Lucy C. Okell, Imperial College London, UK
Maximising the Impact of Antimalarial Treatment

Friday, November 01 | 9:00AM - 12:00PM
Leveraging Data Science to Defeat Malaria I
Room: Ballroom I&II

Speaker 3 of 9
Emilie Pothin, Swiss Tropical and Public Health Institute, Switzerland
Data-Driven Operational Stratification for National Malaria Control Programs

Friday, November 01 | 9:00AM - 12:00PM
Leveraging Data Science to Defeat Malaria I
Room: Ballroom I&II


Coffee Break

Friday, November 01 | 9:00AM - 12:00PM
Leveraging Data Science to Defeat Malaria I
Room: Ballroom I&II

Speaker 5 of 9
Samson Kiware, Ifakara Health Institute, Tanzania
Mosquito Database Management System (MDbMS) Applicable to Diverse Entomological Studies

Friday, November 01 | 9:00AM - 12:00PM
Leveraging Data Science to Defeat Malaria I
Room: Ballroom I&II

Speaker 6 of 9
Hannah Slater, PATH MACEPA, USA
Short Talk: Modelling the Impact of Transmission-Intensity Targeted Intervention Packages for Different Levels of Malaria Transmission in Senegal

Friday, November 01 | 9:00AM - 12:00PM
Leveraging Data Science to Defeat Malaria I
Room: Ballroom I&II

Speaker 7 of 9
Duncan Kobia Athinya, Vestergaard Frandsen Limited, Kenya
Short Talk: Leveraging Available Data for Decision Making in Malaria Vector Control


Friday, November 01 | 9:00AM - 12:00PM
Leveraging Data Science to Defeat Malaria I
Room: Ballroom I&II

Speaker 8 of 9
Maria Tusell, Barcelona Institute for Global Health, Spain
Short Talk: MESA Track: Landscaping Research to Foreseen Emerging Evidence and Guide Decision-Making Processes


Friday, November 01 | 9:00AM - 12:00PM
Leveraging Data Science to Defeat Malaria I
Room: Ballroom I&II

Speaker 9 of 9
Michelle Hsiang, University of Texas Southwestern, USA
Short Talk: The Effectiveness of Malaria Reactive Focal Mass Drug Administration (rfMDA) and Reactive Vector Control (RAVC), a Cluster-Randomised Controlled Two-by-Two Factorial Design Trial from the Low-Endemic Setting of Namibia


Friday, November 01 | 12:00PM - 2:30PM
On Own for Lunch


Friday, November 01 | 12:00PM - 1:00PM
Poster Setup
Room: Ballroom I&II


Friday, November 01 | 1:00PM - 9:30PM
Poster Viewing
Room: Ballroom I&II


Friday, November 01 | 2:30PM - 4:00PM
Workshop
Room: Ballroom I&II

Speaker 1 of 8
* Maria M. Mota, Instituto de Medicina Molecular, Portugal

Friday, November 01 | 2:30PM - 4:00PM
Workshop
Room: Ballroom I&II

Speaker 2 of 8
* Gordon A. Awandare, University of Ghana, Ghana

Friday, November 01 | 2:30PM - 4:00PM
Workshop
Room: Ballroom I&II

Speaker 3 of 8
Maya Fraser, PATH, USA
Evaluating the Impact of Programmatic Mass Drug Administration in Zambia Using Routine Incidence Data


Friday, November 01 | 2:30PM - 4:00PM
Workshop
Room: Ballroom I&II

Speaker 4 of 8
Laurent Dembele, Universite des Sciences Techniques et Technologiques de Bamako, Mali
Toward Novel Antimalarial Discovery against Plasmodium Relapsing Species P. Vivax and P. Ovale, Which Challenge Global Malaria Control and Elimination


Friday, November 01 | 2:30PM - 4:00PM
Workshop
Room: Ballroom I&II

Speaker 5 of 8
Lauren Beth Arendse, University of Cape Town, South Africa
Establishing a Plasmodium Kinase Platform for Target-Based Malaria Drug Discovery


Friday, November 01 | 2:30PM - 4:00PM
Workshop
Room: Ballroom I&II

Speaker 6 of 8
Monica Golumbeanu, Swiss Tropical and Public Health Institute, Switzerland
Quantifying the Effect of Vector Bionomics on the Impact of Vector Control Interventions against Malaria Transmitted by Anopheles Mosquitoes


Friday, November 01 | 2:30PM - 4:00PM
Workshop
Room: Ballroom I&II

Speaker 7 of 8
Steven Gowelo, Wageningen University, Netherlands
Effect of Exposure to Sublethal Doses of Bacillus Thuringiensis Israelensis during Larval Development on Size, Oviposition and Survival of Anopheles coluzzii

Friday, November 01 | 2:30PM - 4:00PM
Workshop
Room: Ballroom I&II

Speaker 8 of 8
Kitty F. Cardwell, Oklahoma State University, USA
Online Metagenome-Based Plasmodium Detection Tool - MiFi®


Friday, November 01 | 4:00PM - 5:00PM
Coffee Available
Room: Ballroom Foyer


Friday, November 01 | 4:00PM - 5:00PM
Panel Discussion on Diversity & Inclusion


Friday, November 01 | 5:00PM - 7:00PM
Leveraging Data Science to Defeat Malaria II
Room: Ballroom I&II

Speaker 1 of 6
* Philip Welkhoff, Bill & Melinda Gates Foundation, USA

Friday, November 01 | 5:00PM - 7:00PM
Leveraging Data Science to Defeat Malaria II
Room: Ballroom I&II

Speaker 2 of 6
Michael White, Institut Pasteur, France
Quantitative Approaches to Understanding P. vivax Epidemiology and Biology

Friday, November 01 | 5:00PM - 7:00PM
Leveraging Data Science to Defeat Malaria II
Room: Ballroom I&II

Speaker 3 of 6
Melissa Penny, Swiss Tropical and Public Health Institute, Switzerland
Models and Machine Learning to Inform Target Product Profiles of New Tools

Friday, November 01 | 5:00PM - 7:00PM
Leveraging Data Science to Defeat Malaria II
Room: Ballroom I&II

Speaker 4 of 6
Daniel Neafsey, Harvard T.H. Chan School of Public Health, USA
Using Parasite and Vector Genetic Relatedness to Inform Malaria Control and Elimination

Friday, November 01 | 5:00PM - 7:00PM
Leveraging Data Science to Defeat Malaria II
Room: Ballroom I&II

Speaker 5 of 6
Mphatso Phiri, Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Malawi
Short Talk: The Duration of Protection from Azithromycin against Malaria When Given alongside Seasonal Malaria Chemoprevention: Secondary Analysis of Data from a Clinical Trial in Hounde, Burkina Faso and Bougouni, Mali


Friday, November 01 | 5:00PM - 7:00PM
Leveraging Data Science to Defeat Malaria II
Room: Ballroom I&II

Speaker 6 of 6
Donnie Mategula, Malawi-Liverpool-Wellcome Trust, Malawi
Short Talk: Geostatistical Analysis of Malawi’s Changing Malaria Transmission from 2010 to 2017


Friday, November 01 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Rose Garden


Friday, November 01 | 7:30PM - 9:30PM
Poster Session 2
Room: Ballroom I&II


Saturday, November 02 | 9:00AM - 12:00PM
Innovating to Enable Malaria Elimination I
Room: Ballroom I&II

Speaker 1 of 8
* Janice A. Culpepper, Bill & Melinda Gates Foundation, USA

Saturday, November 02 | 9:00AM - 12:00PM
Innovating to Enable Malaria Elimination I
Room: Ballroom I&II

Speaker 2 of 8
Thierry T. Diagana, Novartis Institute for Tropical Diseases, USA
The Quest Towards Next Generation Antimalarials: Strengths, Weaknesses and Opportunities

Saturday, November 02 | 9:00AM - 12:00PM
Innovating to Enable Malaria Elimination I
Room: Ballroom I&II

Speaker 3 of 8
Lluis Ballell, GlaxoSmithKline, Spain
Nurturing Novel Drug Discovery Technologies to Address the Malaria Endgame

Saturday, November 02 | 9:00AM - 12:00PM
Innovating to Enable Malaria Elimination I
Room: Ballroom I&II


Coffee Break

Saturday, November 02 | 9:00AM - 12:00PM
Innovating to Enable Malaria Elimination I
Room: Ballroom I&II

Speaker 5 of 8
Maria M. Mota, Instituto de Medicina Molecular, Portugal
The Complexity and the Simplicity of Host-Plasmodium Interactions

Saturday, November 02 | 9:00AM - 12:00PM
Innovating to Enable Malaria Elimination I
Room: Ballroom I&II

Speaker 6 of 8
Alejandro Llanos Cuentas, Universidad Peruana Cayetano Heredia, Peru
Clinical Development and Implementation of Tafenoquine for Vivax Malaria

Saturday, November 02 | 9:00AM - 12:00PM
Innovating to Enable Malaria Elimination I
Room: Ballroom I&II

Speaker 7 of 8
Aissata Barry, Centre National de Recherche et de Formation sur le Paludisme, Burkina Faso
Short Talk: Assessing Skin Sequestration in Gametocyte Donors in Balonghin; Burkina Faso


Saturday, November 02 | 9:00AM - 12:00PM
Innovating to Enable Malaria Elimination I
Room: Ballroom I&II

Speaker 8 of 8
Ashenafi Assefa, Ethiopian Public Health Institute, Ethiopia
Short Talk: Short Course Primaquine for the Radical Cure of Plasmodium Vivax Malaria: A Randomized Placebo-Controlled Multicenter Trial


Saturday, November 02 | 12:00PM - 1:30PM
On Own for Lunch


Saturday, November 02 | 1:30PM - 3:30PM
Innovating to Enable Malaria Elimination II
Room: Ballroom I&II

Speaker 1 of 6
* Helen V. Jamet, Bill & Melinda Gates Foundation, USA

Saturday, November 02 | 1:30PM - 3:30PM
Innovating to Enable Malaria Elimination II
Room: Ballroom I&II

Speaker 2 of 6
Flaminia Catteruccia, Harvard T.H. Chan School of Public Health, USA
Harnessing Mosquitoes to Kill Malaria Parasites

Saturday, November 02 | 1:30PM - 3:30PM
Innovating to Enable Malaria Elimination II
Room: Ballroom I&II

Speaker 3 of 6
Nicholas M. Hamon, IVCC, UK
Innovation in Vector Control: Partnering for Impact and ‘ZERO by 40’

Saturday, November 02 | 1:30PM - 3:30PM
Innovating to Enable Malaria Elimination II
Room: Ballroom I&II

Speaker 4 of 6
Austin Burt, Imperial College London, UK
Gene Drive: From the Bench to the Field

Saturday, November 02 | 1:30PM - 3:30PM
Innovating to Enable Malaria Elimination II
Room: Ballroom I&II

Speaker 5 of 6
Lilian Mbaisi Ang'ang'o, International Centre of Insect Physiology and Ecology, Kenya
Short Talk: A Novel Microsporidian Blocks Plasmodium falciparum Transmission in Anopheles arabiensis Mosquitoes


Saturday, November 02 | 1:30PM - 3:30PM
Innovating to Enable Malaria Elimination II
Room: Ballroom I&II

Speaker 6 of 6
Tibebu Habtewold, Imperial College London, UK
Short Talk: Biological and Methodological Considerations for an Accurate Evaluation of Genetically Engineered Mosquito Carrying Malaria Transmission Blocking Traits for Their Accelerated Rollout


Saturday, November 02 | 3:30PM - 4:00PM
Coffee Available
Room: Ballroom Foyer


Saturday, November 02 | 4:00PM - 5:45PM
Innovating to Enable Malaria Elimination III
Room: Ballroom I&II

Speaker 1 of 5
* Flaminia Catteruccia, Harvard T.H. Chan School of Public Health, USA

Saturday, November 02 | 4:00PM - 5:45PM
Innovating to Enable Malaria Elimination III
Room: Ballroom I&II

Speaker 2 of 5
Helen V. Jamet, Bill & Melinda Gates Foundation, USA
Innovative Vector Control Approaches

Saturday, November 02 | 4:00PM - 5:45PM
Innovating to Enable Malaria Elimination III
Room: Ballroom I&II

Speaker 3 of 5
Fitsum G. Tadesse, Armauer Hansen Research Institute, Ethiopia
The Contribution of Asymptomatic Infections to Transmission

Saturday, November 02 | 4:00PM - 5:45PM
Innovating to Enable Malaria Elimination III
Room: Ballroom I&II

Speaker 4 of 5
Philip Welkhoff, Bill & Melinda Gates Foundation, USA
Innovation in Prevention of Transmission, Improved Case Management, and Enhanced Surveillance for Malaria Burden Reduction and Elimination

Saturday, November 02 | 4:00PM - 5:45PM
Innovating to Enable Malaria Elimination III
Room: Ballroom I&II

Speaker 5 of 5
Kristine Werling, Harvard TH Chan School of Public Health, USA
Short Talk: Plasmodium Development in the Anopheles Mosquito: An Adaptable Relationship That Shapes Malaria Transmission and Control


Saturday, November 02 | 5:45PM - 6:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Ballroom I&II


Saturday, November 02 | 6:15PM - 7:15PM
Social Hour with Lite Bites
Room: Rose Garden
No registration fees are used to fund alcohol served at this function.

Sunday, November 03 | 8:24AM - 8:24AM
Departure


*Session Chair.