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Web Desc
Stromal Cells in Immunity and Disease joint with Fibrosis and Tissue Repair: From Molecules and Mechanics to Therapeutic Approaches Organizer(s): Scott N. Mueller, Jason G. Cyster, Reina E. Mebius and Theresa T. Lu Date: February 19 - 23, 2020 Location: Fairmont Empress Victoria / Victoria Conference Centre, Victoria, BC, Canada Sponsored by Merck & Co., Inc. and Roche For important information on the coronavirus, please click here Summary of Meeting: Non-hematopoietic stromal cells play important roles in many tissues, constructing tissue microenvironments, contributing to tissue repair, defense and immune responses. Within lymphoid organs, stromal cells organize and interact with leukocytes in an immunologically important manner. In addition to organizing T and B cell segregation and expressing lymphocyte survival factors, stromal cells support the migration and interactions between antigen presenting cells and naïve T and B cells during the initiation of immune responses and influence the outcome between tolerance and immunity. Stromal cells also play instrumental roles in coordinating immune responses in non-lymphoid tissues, in inflammatory and autoimmune diseases, and in chronic infection. For instance, stromal cell dysregulation has been seen in HIV infection and in cancer patients. Furthermore, stromal cells are being harnessed for therapeutic applications in several diseases, an area that holds great promise for improving human health. Our understanding of stromal cell populations and their contributions to innate and adaptive immunity as well as immunological diseases, cancer and vaccination has grown exponentially over the past few years. This emerging field has gained enormous momentum due to increasingly sophisticated tools to dissect the fundamental biology and clinical importance of this cellular compartment. This conference is being held jointly with Fibrosis and Tissue Repair: From Molecules and Mechanics to Therapeutic Approaches. This joint pairing will bring together basic and clinical scientists with interdisciplinary interests in stromal cell biology and disease treatment to discuss critical fundamental and translational advances. The goals of this conference are to showcase cutting-edge results and new directions in the field, stimulate interactions and provide a forum for trainees and new investigators to present their work and interact with leaders in the field. Scholarship Deadline: October 17 2019 Discounted Abstract Deadline: October 17 2019 Abstract Deadline: November 20 2019 Discounted Registration Deadline: December 18 2019 Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested. Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Genentech, Inc. We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI149882-01 Funding for this conference was made possible (in part) by 1R13AI149882-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Stromal Cells in Immunity and Disease

joint with Fibrosis and Tissue Repair: From Molecules and Mechanics to Therapeutic Approaches

Organizer(s): Scott N. Mueller, Jason G. Cyster, Reina E. Mebius and Theresa T. Lu

Date: February 19 - 23, 2020
Location: Fairmont Empress Victoria / Victoria Conference Centre, Victoria, BC, Canada

Sponsored by Merck & Co., Inc. and Roche

For important information on the coronavirus, please click here

Summary of Meeting:

Non-hematopoietic stromal cells play important roles in many tissues, constructing tissue microenvironments, contributing to tissue repair, defense and immune responses. Within lymphoid organs, stromal cells organize and interact with leukocytes in an immunologically important manner. In addition to organizing T and B cell segregation and expressing lymphocyte survival factors, stromal cells support the migration and interactions between antigen presenting cells and naïve T and B cells during the initiation of immune responses and influence the outcome between tolerance and immunity. Stromal cells also play instrumental roles in coordinating immune responses in non-lymphoid tissues, in inflammatory and autoimmune diseases, and in chronic infection. For instance, stromal cell dysregulation has been seen in HIV infection and in cancer patients. Furthermore, stromal cells are being harnessed for therapeutic applications in several diseases, an area that holds great promise for improving human health. Our understanding of stromal cell populations and their contributions to innate and adaptive immunity as well as immunological diseases, cancer and vaccination has grown exponentially over the past few years. This emerging field has gained enormous momentum due to increasingly sophisticated tools to dissect the fundamental biology and clinical importance of this cellular compartment. This conference is being held jointly with Fibrosis and Tissue Repair: From Molecules and Mechanics to Therapeutic Approaches. This joint pairing will bring together basic and clinical scientists with interdisciplinary interests in stromal cell biology and disease treatment to discuss critical fundamental and translational advances. The goals of this conference are to showcase cutting-edge results and new directions in the field, stimulate interactions and provide a forum for trainees and new investigators to present their work and interact with leaders in the field.

Scholarship Deadline: October 17 2019

Discounted Abstract Deadline: October 17 2019

Abstract Deadline: November 20 2019

Discounted Registration Deadline: December 18 2019

Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI149882-01
Funding for this conference was made possible (in part) by 1R13AI149882-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Wednesday, February 19 \| 4:00PM - 8:00PM Arrival and Registration Room: Palm Court
Wednesday, February 19 \| 6:00PM - 8:00PM Welcome Mixer Room: Palm Court No registration fees are used to fund alcohol served at this function.
Thursday, February 20 \| 7:00AM - 8:00AM Breakfast Room: Crystal Gardens
Thursday, February 20 \| 7:30AM - 8:00AM Poster Setup Room: Crystal Gardens
Thursday, February 20 \| 8:00AM - 7:00PM Poster Viewing Room: Crystal Gardens
Thursday, February 20 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Salon A/B Speaker 1 of 4 * Scott N. Mueller, University of Melbourne, Australia
Thursday, February 20 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Salon A/B Speaker 2 of 4 * Shannon J. Turley, Genentech, Inc., USA
Thursday, February 20 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Salon A/B Speaker 3 of 4 David A. Brenner, University of California, San Diego, USA Linking Inflammation and Myofibroblast Activation
Thursday, February 20 \| 8:00AM - 9:30AM Welcome and Keynote Session (Joint) Room: Salon A/B Speaker 4 of 4 Ruslan Medzhitov, HHMI/Yale University School of Medicine, USA Macrophage-Fibroblast Circuits
Thursday, February 20 \| 9:30AM - 10:00AM Coffee Break Room: Prefunction
Thursday, February 20 \| 10:00AM - 12:00PM Stromal Cells in Lymphoid Tissue Development Room: Salon C Speaker 1 of 6 * Jason G. Cyster, HHMI/University of California, San Francisco, USA
Thursday, February 20 \| 10:00AM - 12:00PM Stromal Cells in Lymphoid Tissue Development Room: Salon C Speaker 2 of 6 Burkhard Ludewig, Kantonsspital St. Gallen, Switzerland Fibroblastic Stromal Cells Direct Lymphoid Organ Development and Immune Activation
Thursday, February 20 \| 10:00AM - 12:00PM Stromal Cells in Lymphoid Tissue Development Room: Salon C Speaker 3 of 6 Reina E. Mebius, Amsterdam UMC-VUmc, Netherlands Control of the Adaptive Immunity by Lymph Node Stromal Cells
Thursday, February 20 \| 10:00AM - 12:00PM Stromal Cells in Lymphoid Tissue Development Room: Salon C Speaker 4 of 6 Sanjiv A. Luther, University of Lausanne, Switzerland Fibroblasts of the Intestinal Lamina Propria are Important Niche Cells Regulating IgA+ Plasma Cell Homeostasis and Function
Thursday, February 20 \| 10:00AM - 12:00PM Stromal Cells in Lymphoid Tissue Development Room: Salon C Speaker 5 of 6 Mark C. Coles, University of Oxford, UK Short Talk: B-Cell Zone Reticular Cell Microenvironments Shape Chemotactic Gradient Formation
Thursday, February 20 \| 10:00AM - 12:00PM Stromal Cells in Lymphoid Tissue Development Room: Salon C Speaker 6 of 6 Anne Chauveau, Oxford University, UK Short Talk: Perivascular Pathways Direct One-Way Migration of T Cells into Splenic T Zones
Thursday, February 20 \| 10:00AM - 12:00PM Tissue Fibroblasts and Pericytes in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 1 of 7 * Shannon J. Turley, Genentech, Inc., USA
Thursday, February 20 \| 10:00AM - 12:00PM Tissue Fibroblasts and Pericytes in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 2 of 7 * Dean Sheppard, University of California, San Francisco, USA
Thursday, February 20 \| 10:00AM - 12:00PM Tissue Fibroblasts and Pericytes in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 3 of 7 Jonathan M. Kurie, University of Texas MD Anderson Cancer Center, USA The Fibrotic Tumor Stroma
Thursday, February 20 \| 10:00AM - 12:00PM Tissue Fibroblasts and Pericytes in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 4 of 7 Yuval Rinkevich, Helmholtz Zentrum München, GmbH, Germany Two Succeeding Fibroblastic Lineages Drive Dermal Development and the Transition from Regeneration to Scarring
Thursday, February 20 \| 10:00AM - 12:00PM Tissue Fibroblasts and Pericytes in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 5 of 7 Scott M. Turner, Pliant Therapeutics, USA Identification and Evaluation of Small Molecule Integrin Inhibitors: From Cell Systems to Human Trials
Thursday, February 20 \| 10:00AM - 12:00PM Tissue Fibroblasts and Pericytes in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 6 of 7 Tatsuya Tsukui, University of California, San Francisco, USA Short Talk: Collagen-Producing Lung Cell Atlas Identifies Multiple Subsets with Distinct Localization and Relevance to Fibrosis
Thursday, February 20 \| 10:00AM - 12:00PM Tissue Fibroblasts and Pericytes in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 7 of 7 Dianhua Jiang, Cedars-Sinai Medical Center, USA Short Talk: Longitudinal Transcriptomics Identifies Fibroblast Subtypes during Lung Development and Fibrosis
Thursday, February 20 \| 12:00PM - 1:00PM Lunch Room: Crystal Gardens
Thursday, February 20 \| 12:00PM - 2:30PM Poster Session 1 Room: Crystal Gardens
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Stromal Orchestration and Immune Responses Room: Salon C Speaker 1 of 10 * Mandy J. McGeachy, University of Pittsburgh, USA
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Stromal Orchestration and Immune Responses Room: Salon C Speaker 2 of 10 * Ruth Ganss, Harry Perkins Institute of Medical Research, Australia
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Stromal Orchestration and Immune Responses Room: Salon C Speaker 3 of 10 Catarina Gago da Graca, Amsterdam UMC - VUMC, Netherlands Characterization of MHC-II Expressing FRCs in Steady State and Inflammatory Conditions
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Stromal Orchestration and Immune Responses Room: Salon C Speaker 4 of 10 Ana Martínez-Riaño, Francis Crick Institute, UK Cellular Dynamics of Follicular Dendritic Cells Control Antigen Presentation during the Humoral Response
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Stromal Orchestration and Immune Responses Room: Salon C Speaker 5 of 10 Yannick Alexandre, University of Melbourne, Australia Mesenchymal Stromal Cells Coordinate Protective Adaptive Immune Responses during Viral Infections in the Spleen
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Stromal Orchestration and Immune Responses Room: Salon C Speaker 6 of 10 Joshua D. Brandstadter, University of Pennsylvania, USA Distinct Populations of Fibroblastic Stromal Cells in Spleen and Lymph Nodes Express Individual Notch Ligands and Prime Graft-versus-Host Disease after Bone Marrow Transplantation
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Stromal Orchestration and Immune Responses Room: Salon C Speaker 7 of 10 Junko Sawada, Johns Hopkins All Children's Hospital, USA TNFa Upregulates R-Ras Expression in High Endothelial Venule and Capillary Endothelium in Lymph Node, Facilitating T Cell Recruitment upon Inflammation
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Stromal Orchestration and Immune Responses Room: Salon C Speaker 8 of 10 Jennifer Eom, University of Auckland, New Zealand Phenotypically Distinct Fibroblastic Populations in Melanoma-Infiltrated Human Lymph Nodes Provide Unique Microenvironment for T Lymphocytes
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Stromal Orchestration and Immune Responses Room: Salon C Speaker 9 of 10 Ian Boothby, University of California, San Francisco, USA Neonatal Tregs Suppress the Development of a Stromal Niche for Th2 Cells in Skin
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Stromal Orchestration and Immune Responses Room: Salon C Speaker 10 of 10 Ari B. Molofsky, University of California, San Francisco, USA Stromal Crosstalk with Type 2 Immunity at Tissue Adventitial Niches
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Core Mechanisms versus Organ Specific Mediators of Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 1 of 10 * Thirumalai R. Ramalingam, Genentech, Inc., USA
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Core Mechanisms versus Organ Specific Mediators of Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 2 of 10 * Karen Piper Hanley, University of Manchester, UK
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Core Mechanisms versus Organ Specific Mediators of Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 3 of 10 Daniel Abebayehu, University of Virginia, USA Inflammatory Cytokines Induce Unique Immuno-Fibroblast Subpopulations Prone to Myofibroblastic Differentiation
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Core Mechanisms versus Organ Specific Mediators of Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 4 of 10 Daryle J. DePianto, Genentech, Inc., USA Molecular Mapping of Epithelial Cell Senescence in IPF
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Core Mechanisms versus Organ Specific Mediators of Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 5 of 10 Tien Peng, University of California, San Francisco, USA Gli1+ Mesenchymal Cells Modulate Epithelial Progenitor Metaplasia in Lung Fibrosis
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Core Mechanisms versus Organ Specific Mediators of Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 6 of 10 Lynn M. Williams, Kennedy Institute of Rheumatology, UK CREBBP/EP300 Regulation of Collagen VI is a Key Determinant of the Myofibroblast Phenotype in Human Fibrosis
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Core Mechanisms versus Organ Specific Mediators of Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 7 of 10 Sonia Chothani, Duke-NUS Medical School, Singapore RNA-Binding Proteins: Drivers of Translational Regulation in Cardiac Fibrosis
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Core Mechanisms versus Organ Specific Mediators of Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 8 of 10 Preethi Vijayaraj, University of California, Los Angeles, USA Fibrotic Lung Disease is Associated with Proliferation and Desquamation of Ciliated Bronchiolar Epithelium
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Core Mechanisms versus Organ Specific Mediators of Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 9 of 10 Ahmad N. Nabhan, Genentech, Inc., USA A Molecular Cell Atlas of the Human Lung from Single Cell RNA Sequencing
Thursday, February 20 \| 2:30PM - 4:30PM Workshop 1: Core Mechanisms versus Organ Specific Mediators of Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 10 of 10 Veronica Larcher, Goethe University, Germany Parallel Lineage Tracing Studies Establish Fibroblasts as the Prevailing in vivo Adipocyte Progenitor
Thursday, February 20 \| 4:30PM - 5:00PM Coffee Available Room: Prefunction
Thursday, February 20 \| 5:00PM - 7:00PM Stromal Cells and Immunity in Non-Lymphoid Tissues Room: Salon C Speaker 1 of 6 * Ari B. Molofsky, University of California, San Francisco, USA
Thursday, February 20 \| 5:00PM - 7:00PM Stromal Cells and Immunity in Non-Lymphoid Tissues Room: Salon C Speaker 2 of 6 Theresa T. Lu, Hospital for Special Surgery/Weill Cornell Medicine, USA Langerhans Cells and Skin Protection in Lupus Photosensitivity
Thursday, February 20 \| 5:00PM - 7:00PM Stromal Cells and Immunity in Non-Lymphoid Tissues Room: Salon C Speaker 3 of 6 Shruti Naik, New York University, USA Inflammatory Tuning of Epithelial Stem Cells
Thursday, February 20 \| 5:00PM - 7:00PM Stromal Cells and Immunity in Non-Lymphoid Tissues Room: Salon C Speaker 4 of 6 Jeremiah Bernier-Latmani, University of Lausanne, Switzerland Blood Vessel / Telocyte Crosstalk at the Small Intestinal Villus Tip
Thursday, February 20 \| 5:00PM - 7:00PM Stromal Cells and Immunity in Non-Lymphoid Tissues Room: Salon C Speaker 5 of 6 Matthew B. Buechler, Genentech, Inc., USA Short Talk: Tissue-Specific Programming Determines Tenor of Fibroblast and Mesothelial Cell Plasticity and Activation
Thursday, February 20 \| 5:00PM - 7:00PM Stromal Cells and Immunity in Non-Lymphoid Tissues Room: Salon C Speaker 6 of 6 Bing Su, Shanghai JiaoTong University School of Medicine, China Short Talk: Map3k2-Regulated Intestinal Stromal Cells Define a Stem Cell Niche via Wnt Agonist R-spondin1
Thursday, February 20 \| 5:00PM - 7:00PM Myeloid Cells in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 1 of 7 * Neil C. Henderson, University of Edinburgh, Queen's Medical Research Institute, UK
Thursday, February 20 \| 5:00PM - 7:00PM Myeloid Cells in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 2 of 7 * Tatiana Kisseleva, University of California, San Diego, USA
Thursday, February 20 \| 5:00PM - 7:00PM Myeloid Cells in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 3 of 7 Akira Shizuo, Osaka University, Japan Molecular Mechanism of Bleomycin-Induced Lung Fibrosis
Thursday, February 20 \| 5:00PM - 7:00PM Myeloid Cells in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 4 of 7 Harris Perlman, Northwestern University, USA Monocyte Derived Macrophages in Inflammation and Fibrosis
Thursday, February 20 \| 5:00PM - 7:00PM Myeloid Cells in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 5 of 7 Frank Tacke, Charité Universitätsmedizin Berlin, Germany Macrophage Heterogeneity in Liver Homeostasis, Inflammation, and Fibrosis
Thursday, February 20 \| 5:00PM - 7:00PM Myeloid Cells in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 6 of 7 Prakash Ramachandran, University of Edinburgh, UK Short Talk: Defining a Novel Macrophage Subpopulation Which Promotes Human Liver Fibrosis
Thursday, February 20 \| 5:00PM - 7:00PM Myeloid Cells in Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 7 of 7 Resat Cinar, NIAAA, National Institutes of Health, USA Short Talk: Cannabinoid 1 Receptors (CB1R) in Myeloid Cells Promote Fibrosis in Lung: Paracrine Control Drives Fibroproliferative Microenvironment via Multiple Mechanisms
Thursday, February 20 \| 7:00PM - 7:00PM On Own for Dinner
Friday, February 21 \| 7:00AM - 8:00AM Breakfast Room: Crystal Gardens
Friday, February 21 \| 8:00AM - 11:00AM Stromal Cell Functions in Primary and Secondary Lymphoid Tis sues Room: Salon C Speaker 1 of 9 * Reina E. Mebius, Amsterdam UMC-VUmc, Netherlands
Friday, February 21 \| 8:00AM - 11:00AM Stromal Cell Functions in Primary and Secondary Lymphoid Tis sues Room: Salon C Speaker 2 of 9 João Pereira, Yale University School of Medicine, USA Cell Circuits, B cells, and Systemic Responses to Microbial Infections
Friday, February 21 \| 8:00AM - 11:00AM Stromal Cell Functions in Primary and Secondary Lymphoid Tis sues Room: Salon C Speaker 3 of 9 Madelon M. E. de Jong, Erasmus MC, Netherlands Short Talk: A Unique Inflammatory Stromal Cell Population Associated with NFkappaB Signaling in the Multiple Myeloma Bone Marrow
Friday, February 21 \| 8:00AM - 11:00AM Stromal Cell Functions in Primary and Secondary Lymphoid Tis sues Room: Salon C Speaker 4 of 9 Tomoya Katakai, Niigata University, Japan Stromal Cell Diversity in Lymph Nodes
Friday, February 21 \| 8:00AM - 11:00AM Stromal Cell Functions in Primary and Secondary Lymphoid Tis sues Room: Salon C Coffee Break
Friday, February 21 \| 8:00AM - 11:00AM Stromal Cell Functions in Primary and Secondary Lymphoid Tis sues Room: Salon C Speaker 6 of 9 Beth A. Tamburini, University of Colorado Denver Anchutz Medical Campus, USA Control of Immune Responses in Lymph Nodes by Lymphatic Endothelial Cells
Friday, February 21 \| 8:00AM - 11:00AM Stromal Cell Functions in Primary and Secondary Lymphoid Tis sues Room: Salon C Speaker 7 of 9 Dragos Cristian Dasoveanu, Hospital for Special Surgery, USA Short Talk: Lymph Node Stromal CCL2 Limits Antibody Responses
Friday, February 21 \| 8:00AM - 11:00AM Stromal Cell Functions in Primary and Secondary Lymphoid Tis sues Room: Salon C Speaker 8 of 9 Natalia Pikor, Kantonsspital St. Gallen, Switzerland Short Talk: CXCL12-Dependent Remodeling of Light and Dark Zone Follicular Dendritic Cells Governs the Germinal Center Response
Friday, February 21 \| 8:00AM - 11:00AM Stromal Cell Functions in Primary and Secondary Lymphoid Tis sues Room: Salon C Speaker 9 of 9 Lorenz Jahn, Memorial Sloan Kettering Cancer Center, USA Short Talk: Transcriptional Responses of Thymic Epithelium, Endothelium, and Mesenchyme to Acute Injury on a Single Cell Level
Friday, February 21 \| 8:00AM - 11:00AM Advances in Organ Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 1 of 9 * Cory M. Hogaboam, Cedars-Sinai Medical Center, USA
Friday, February 21 \| 8:00AM - 11:00AM Advances in Organ Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 2 of 9 * Katalin Susztak, University of Pennsylvania, USA
Friday, February 21 \| 8:00AM - 11:00AM Advances in Organ Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 3 of 9 Ivan O. Rosas, Baylor College of Medicine, USA Insights into the Complexity and Diversity of Cell Populations in IPF and COPD using Single Cell RNA-seq
Friday, February 21 \| 8:00AM - 11:00AM Advances in Organ Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 4 of 9 Neil C. Henderson, University of Edinburgh, Queen's Medical Research Institute, UK Using Single Cell Genomics to Decode the Hepatic Fibrotic Niche
Friday, February 21 \| 8:00AM - 11:00AM Advances in Organ Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Coffee Break
Friday, February 21 \| 8:00AM - 11:00AM Advances in Organ Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 6 of 9 Katalin Susztak, University of Pennsylvania, USA Fatty Acid Oxidation in Tubular Epithelial Cells Regulates Kidney Fibrosis
Friday, February 21 \| 8:00AM - 11:00AM Advances in Organ Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 7 of 9 Harry (Hal) C. Dietz, Johns Hopkins University School of Medicine, Blade Therapeutics, USA New Mechanisms and Vulnerabilities of Fibrosis
Friday, February 21 \| 8:00AM - 11:00AM Advances in Organ Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 8 of 9 Ying Wei, University of California, San Francisco, USA Short Talk: Reversal of TGFbeta1-Driven Pro-Fibrotic State in Pulmonary Fibrosis Patients
Friday, February 21 \| 8:00AM - 11:00AM Advances in Organ Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 9 of 9 Satish K. Madala, Cincinnati Children's Hospital Medical Center, USA Short Talk: Transcriptional Regulation of Fibroblast Activation in Severe Fibrotic Lung Disease
Friday, February 21 \| 11:00AM - 5:00PM On Own for Lunch
Friday, February 21 \| 11:00AM - 1:00PM Poster Setup Room: Crystal Gardens
Friday, February 21 \| 1:00PM - 10:00PM Poster Viewing Room: Crystal Gardens
Friday, February 21 \| 2:30PM - 4:30PM Workshop 2: Novel Technologies and Models in Stromal Cell Bi ology and Fibrosis (Joint) Room: Salon A/B Speaker 1 of 9 * Lucie Peduto, Institut Pasteur, France
Friday, February 21 \| 2:30PM - 4:30PM Workshop 2: Novel Technologies and Models in Stromal Cell Bi ology and Fibrosis (Joint) Room: Salon A/B Speaker 2 of 9 * Michael Underhill, University of British Columbia, Canada
Friday, February 21 \| 2:30PM - 4:30PM Workshop 2: Novel Technologies and Models in Stromal Cell Bi ology and Fibrosis (Joint) Room: Salon A/B Speaker 3 of 9 Lee A. Borthwick, Newcastle University, UK A Bioreactor Technology for Modelling Fibrosis in Human and Rodent Precision-Cut Liver Slices
Friday, February 21 \| 2:30PM - 4:30PM Workshop 2: Novel Technologies and Models in Stromal Cell Bi ology and Fibrosis (Joint) Room: Salon A/B Speaker 4 of 9 Michael Jeffrey Podolsky, University of California, San Francisco, USA Genome-Wide Screens Identify Novel Regulators of Cell-Mediated Collagen Degradation
Friday, February 21 \| 2:30PM - 4:30PM Workshop 2: Novel Technologies and Models in Stromal Cell Bi ology and Fibrosis (Joint) Room: Salon A/B Speaker 5 of 9 Maha AlSharqi, McGill University, Canada Development of CD109-Based Molecules as TGF-Beta Antagonists and Antifibrotic Agents in Scleroderma Fibroblasts
Friday, February 21 \| 2:30PM - 4:30PM Workshop 2: Novel Technologies and Models in Stromal Cell Bi ology and Fibrosis (Joint) Room: Salon A/B Speaker 6 of 9 Laura Elisabeth Kähäri, University of Turku, Finland Targeted Delivery of Antibodies to the Draining Lymph Node through the Subcapsular Sinus Floor
Friday, February 21 \| 2:30PM - 4:30PM Workshop 2: Novel Technologies and Models in Stromal Cell Bi ology and Fibrosis (Joint) Room: Salon A/B Speaker 7 of 9 Kristine Lai, Cornell University, USA ImmuneChip with Stromal-Specific Chemokine Gradient to Capture Germinal Center B Cell Dynamics
Friday, February 21 \| 2:30PM - 4:30PM Workshop 2: Novel Technologies and Models in Stromal Cell Bi ology and Fibrosis (Joint) Room: Salon A/B Speaker 8 of 9 Heather J. Faust, Brigham and Womens Hospital, USA Utilization of 3D Organoids to Study Synovial Fibroblast-Immune Cell Interactions
Friday, February 21 \| 2:30PM - 4:30PM Workshop 2: Novel Technologies and Models in Stromal Cell Bi ology and Fibrosis (Joint) Room: Salon A/B Speaker 9 of 9 Anastasia Kousa, Memorial Sloan Kettering Sloan Cancer Center, USA Construction of a Cellular Interactome Across Epithelium, Endothelium, and Mesenchyme During Thymic Regeneration
Friday, February 21 \| 4:30PM - 5:00PM Coffee Available Room: Prefunction
Friday, February 21 \| 5:00PM - 7:00PM Endothelial Cells in Immunity and Disease Room: Salon C Speaker 1 of 6 * Amanda Lund, New York University, USA
Friday, February 21 \| 5:00PM - 7:00PM Endothelial Cells in Immunity and Disease Room: Salon C Speaker 2 of 6 Scott N. Mueller, University of Melbourne, Australia Disentangling the Splenic Stromal Cell Network in Health in Disease
Friday, February 21 \| 5:00PM - 7:00PM Endothelial Cells in Immunity and Disease Room: Salon C Speaker 3 of 6 Cornelia Halin, ETH Zürich, Switzerland Leukocyte Migration through Afferent Lymphatic Vessels
Friday, February 21 \| 5:00PM - 7:00PM Endothelial Cells in Immunity and Disease Room: Salon C Speaker 4 of 6 Ulrich H. Von Andrian, Harvard Medical School, USA Lymphocyte Patrol of Blood Vessel Endothelium
Friday, February 21 \| 5:00PM - 7:00PM Endothelial Cells in Immunity and Disease Room: Salon C Speaker 5 of 6 Akira Takeda, University of Turku, Finland Short Talk: Human Lymphatic Endothelial Heterogeneity in Health and Disease
Friday, February 21 \| 5:00PM - 7:00PM Endothelial Cells in Immunity and Disease Room: Salon C Speaker 6 of 6 Madeline Churchill, Oregon Health and Science University, USA Short Talk: Dermal Lymphatic Capillary ‘Zippering’ Enhances CD8+ T Cell Priming Following Cutaneous Viral Infection
Friday, February 21 \| 5:00PM - 7:00PM Unique Drivers of Inflammation and Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 1 of 7 * Boris Hinz, University of Toronto, Canada
Friday, February 21 \| 5:00PM - 7:00PM Unique Drivers of Inflammation and Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 2 of 7 * Maria Trojanowska, Boston University School of Medicine, USA
Friday, February 21 \| 5:00PM - 7:00PM Unique Drivers of Inflammation and Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 3 of 7 Anissa A. Widjaja, DUKE-NUS Medical School, Singapore Hiding in Plain Sight: Interleukin-11 Emerges as a Master Regulator of Fibrosis, Tissue Integrity and Stromal Inflammation
Friday, February 21 \| 5:00PM - 7:00PM Unique Drivers of Inflammation and Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 4 of 7 Pilar Alcaide, Tufts University School of Medicine, USA T Cell Regulation of Cardiac Fibrosis
Friday, February 21 \| 5:00PM - 7:00PM Unique Drivers of Inflammation and Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 5 of 7 Jelena Mann, Newcastle University, UK Epigenetics and Fibrosis
Friday, February 21 \| 5:00PM - 7:00PM Unique Drivers of Inflammation and Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 6 of 7 Ning Ding, Genentech, Inc., USA Short Talk: WISP1 Activates MRTF to Promote the Progression of Established Liver Fibrosis
Friday, February 21 \| 5:00PM - 7:00PM Unique Drivers of Inflammation and Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 7 of 7 Akiyoshi Uemura, Nagoya City University, Japan Short Talk: Activated Microglia Promote Fibrosis in Pericyte-Deficient Retina
Friday, February 21 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Crystal Gardens No registration fees are used to fund alcohol served at this function.
Friday, February 21 \| 7:30PM - 10:00PM Poster Session 2 Room: Crystal Gardens
Saturday, February 22 \| 7:00AM - 8:00AM Breakfast Room: Crystal Gardens
Saturday, February 22 \| 8:00AM - 11:00AM Stromal Cells in Cancer and Anti-Tumor Immunity Room: Salon C Speaker 1 of 8 * Hélène Salmon, Institut Curie and Mount Sinai School of Medicine, France
Saturday, February 22 \| 8:00AM - 11:00AM Stromal Cells in Cancer and Anti-Tumor Immunity Room: Salon C Speaker 2 of 8 Amanda Lund, New York University, USA Lymphatic Vessels and the Cancer Immunity Life Cycle
Saturday, February 22 \| 8:00AM - 11:00AM Stromal Cells in Cancer and Anti-Tumor Immunity Room: Salon C Speaker 3 of 8 Anne Fletcher, Monash University, Australia Human T Cell Suppression Triggered through Cross-Talk with Cancer-Associated Fibroblasts
Saturday, February 22 \| 8:00AM - 11:00AM Stromal Cells in Cancer and Anti-Tumor Immunity Room: Salon C Coffee Break
Saturday, February 22 \| 8:00AM - 11:00AM Stromal Cells in Cancer and Anti-Tumor Immunity Room: Salon C Speaker 5 of 8 Ruth Ganss, Harry Perkins Institute of Medical Research, Australia Stromal Remodeling and Targeting in Cancer
Saturday, February 22 \| 8:00AM - 11:00AM Stromal Cells in Cancer and Anti-Tumor Immunity Room: Salon C Speaker 6 of 8 Jacqui Shields, University of Cambridge, UK Beyond the Cancer Cell: Exploring the Tumour Stroma as Immune Modulators
Saturday, February 22 \| 8:00AM - 11:00AM Stromal Cells in Cancer and Anti-Tumor Immunity Room: Salon C Speaker 7 of 8 John Andrew Grout, Mount Sinai School of Medicine, USA Short Talk: Single Cell Transcriptomic Dissection of the Stromal Cell Compartment in Early-Stage Non-Small Cell Lung Carcinoma (NSCLC)
Saturday, February 22 \| 8:00AM - 11:00AM Stromal Cells in Cancer and Anti-Tumor Immunity Room: Salon C Speaker 8 of 8 Anthony B. Rodriguez, University of Virginia School of Medicine, USA Short Talk: Tumor-Associated Fibroblasts Act As Surrogate Lymphoid Tissue Organizer Cells That Orchestrate Tumor-Associated Tertiary Lymphoid Structure Development
Saturday, February 22 \| 8:00AM - 11:00AM Novel Pathways and Strategies to Ameliorate Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 1 of 8 * Derek A. Mann, Newcastle University, UK
Saturday, February 22 \| 8:00AM - 11:00AM Novel Pathways and Strategies to Ameliorate Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 2 of 8 Thomas A. Wynn, Pfizer, USA Targeting Type 1 and Type 2 Fibrosis
Saturday, February 22 \| 8:00AM - 11:00AM Novel Pathways and Strategies to Ameliorate Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 3 of 8 Tatiana Kisseleva, University of California, San Diego, USA The Role of Mesothelin in the Pathogenesis of Parenchymal Organs
Saturday, February 22 \| 8:00AM - 11:00AM Novel Pathways and Strategies to Ameliorate Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Coffee Break
Saturday, February 22 \| 8:00AM - 11:00AM Novel Pathways and Strategies to Ameliorate Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 5 of 8 Scott L. Friedman, Icahn School of Medicine at Mount Sinai, USA Target Selection and Validation for Antifibrotic Therapies in Liver
Saturday, February 22 \| 8:00AM - 11:00AM Novel Pathways and Strategies to Ameliorate Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 6 of 8 Christine Kim Garcia, Columbia University Medical Center, USA Pulmonary Fibrosis: Inherited Susceptibilities and Personalized Prognostics
Saturday, February 22 \| 8:00AM - 11:00AM Novel Pathways and Strategies to Ameliorate Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 7 of 8 Jennifer Y. Chen, University of California, San Francisco, USA Short Talk: Targeting Acid Ceramidase Inhibits YAP/TAZ Mechanosignaling to Ameliorate Fibrosis
Saturday, February 22 \| 8:00AM - 11:00AM Novel Pathways and Strategies to Ameliorate Fibrosis This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 8 of 8 Andreas Schlitzer, University of Bonn, Germany Short Talk: Inflammation Experienced Trem2+ Monocyte-Derived Alveolar Macrophages Control Pulmonal Inflammatory Reactivity and Protect from Lung Fibrosis
Saturday, February 22 \| 11:00AM - 5:00PM On Own for Lunch
Saturday, February 22 \| 11:00AM - 1:00PM Poster Setup Room: Crystal Gardens
Saturday, February 22 \| 1:00PM - 10:00PM Poster Viewing Room: Crystal Gardens
Saturday, February 22 \| 4:30PM - 5:00PM Coffee Available Room: Prefunction
Saturday, February 22 \| 5:00PM - 7:00PM Stroma Cell Contributions During Infection and Inflammation Room: Salon C Speaker 1 of 6 * Sanjiv A. Luther, University of Lausanne, Switzerland
Saturday, February 22 \| 5:00PM - 7:00PM Stroma Cell Contributions During Infection and Inflammation Room: Salon C Speaker 2 of 6 Melody A. Swartz, University of Chicago, USA Role of Lymphatic Endothelial Cells in the Regulation of T Cell Memory
Saturday, February 22 \| 5:00PM - 7:00PM Stroma Cell Contributions During Infection and Inflammation Room: Salon C Speaker 3 of 6 Susan R. Schwab, New York University School of Medicine, USA Exit Strategies: S1P Gradients in Inflammation
Saturday, February 22 \| 5:00PM - 7:00PM Stroma Cell Contributions During Infection and Inflammation Room: Salon C Speaker 4 of 6 Marc Bajénoff, Centre d'Immunologie Marseille-Luminy, France Lymphoid Stromal Cells are Essential Components of Macrophage Niches
Saturday, February 22 \| 5:00PM - 7:00PM Stroma Cell Contributions During Infection and Inflammation Room: Salon C Speaker 5 of 6 Mandy J. McGeachy, University of Pittsburgh, USA Short Talk: IL-17 Signals to Lymphoid Stroma to Support Function during Th17 Autoimmune and Th1/CTL Anti-Viral Responses
Saturday, February 22 \| 5:00PM - 7:00PM Stroma Cell Contributions During Infection and Inflammation Room: Salon C Speaker 6 of 6 David F. Boyd, St. Jude Children's Research Hospital, USA Short Talk: Inflammatory Fibroblasts Determine the Outcome of Severe Respiratory Infection in an ADAMTS4-Dependent Manner
Saturday, February 22 \| 5:00PM - 7:00PM Distinct and Common Mechanisms of Fibrosis Revealed by Diffe rent Tissues This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 1 of 7 * Robert V. Martinez, Pfizer Inc., USA
Saturday, February 22 \| 5:00PM - 7:00PM Distinct and Common Mechanisms of Fibrosis Revealed by Diffe rent Tissues This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 2 of 7 * Anna Burkart Sadusky, NIDDK, National Institutes of Health, USA
Saturday, February 22 \| 5:00PM - 7:00PM Distinct and Common Mechanisms of Fibrosis Revealed by Diffe rent Tissues This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 3 of 7 Florian Rieder, Cleveland Clinic, USA Mechanisms and Future Clinical Trial Endpoints of Intestinal Fibrosis
Saturday, February 22 \| 5:00PM - 7:00PM Distinct and Common Mechanisms of Fibrosis Revealed by Diffe rent Tissues This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 4 of 7 Daniel Tschumperlin, Mayo Clinic, USA Targeting YAP/TAZ in Lung and Liver Fibrosis
Saturday, February 22 \| 5:00PM - 7:00PM Distinct and Common Mechanisms of Fibrosis Revealed by Diffe rent Tissues This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 5 of 7 Valerie M. Weaver, University of California, San Francisco, USA Tissue Tension Induces Matricellular Fibrosis and Tumor Progression in Pancreas
Saturday, February 22 \| 5:00PM - 7:00PM Distinct and Common Mechanisms of Fibrosis Revealed by Diffe rent Tissues This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 6 of 7 Tapas Mukherjee, University of Toronto, Canada Short Talk: Deciphering the Influence of Crohn's Disease-Associated Genetic Risk Factor, NOD2 in Intestinal Fibrosis
Saturday, February 22 \| 5:00PM - 7:00PM Distinct and Common Mechanisms of Fibrosis Revealed by Diffe rent Tissues This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 7 of 7 Ji Zhang, Merck & Co., Inc., USA Short Talk: Molecular Profiling Reveals A Common Metabolic Signature of Tissue Fibrosis
Saturday, February 22 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Crystal Gardens No registration fees are used to fund alcohol served at this function.
Saturday, February 22 \| 7:30PM - 10:00PM Poster Session 3 Room: Crystal Gardens
Sunday, February 23 \| 7:00AM - 8:00AM Breakfast Room: Crystal Gardens
Sunday, February 23 \| 8:00AM - 11:15AM Interrogating Stromal Functions in Disease Room: Salon C Speaker 1 of 9 * Theresa T. Lu, Hospital for Special Surgery/Weill Cornell Medicine, USA
Sunday, February 23 \| 8:00AM - 11:15AM Interrogating Stromal Functions in Disease Room: Salon C Speaker 2 of 9 Michael B. Brenner, Harvard Medical School, USA Fibroblast Positional Identity Controlled by Inductive Notch Signaling Underlies Pathologic Damage in Inflammatory Arthritis
Sunday, February 23 \| 8:00AM - 11:15AM Interrogating Stromal Functions in Disease Room: Salon C Speaker 3 of 9 Lucie Peduto, Institut Pasteur, France Mesenchymal Cells in Pathology and Tissue Repair
Sunday, February 23 \| 8:00AM - 11:15AM Interrogating Stromal Functions in Disease Room: Salon C Coffee Break
Sunday, February 23 \| 8:00AM - 11:15AM Interrogating Stromal Functions in Disease Room: Salon C Speaker 5 of 9 George A. Kollias, Alexander Fleming Biomedical Sciences Research Center, Greece Mesenchymal Causalities in Inflammation, Immunity and Cancer
Sunday, February 23 \| 8:00AM - 11:15AM Interrogating Stromal Functions in Disease Room: Salon C Speaker 6 of 9 Ankur Singh, Cornell University, USA Immune Organoids to Study Immunity and Epigenetics in Health and Diseases
Sunday, February 23 \| 8:00AM - 11:15AM Interrogating Stromal Functions in Disease Room: Salon C Speaker 7 of 9 Manolis Roulis, Yale University, USA Short Talk: Paracrine Orchestration of Intestinal Tumorigenesis by a Confined Mesenchymal Niche
Sunday, February 23 \| 8:00AM - 11:15AM Interrogating Stromal Functions in Disease Room: Salon C Speaker 8 of 9 Viviana Cremasco, Novartis Institutes for BioMedical Research, USA Short Talk: TGFß-Blockade Uncovers Stromal Plasticity in Tumors by Revealing the Existence of a Novel Subset of Interferon-Licensed Fibroblasts
Sunday, February 23 \| 8:00AM - 11:15AM Interrogating Stromal Functions in Disease Room: Salon C Speaker 9 of 9 Guillaume Harlé, University of Geneva, Switzerland Short Talk: Autophagy in Lymphatic Endothelial Cells Dampens Collagen-Induced Arthritis Severity by Regulating Sphingosine-1-Phosphate Production
Sunday, February 23 \| 8:00AM - 11:00AM Progenitor Cells in Tissue Repair and Organ Regeneration This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 1 of 9 * Andrew Leask, University of Saskatoon, Canada
Sunday, February 23 \| 8:00AM - 11:00AM Progenitor Cells in Tissue Repair and Organ Regeneration This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 2 of 9 Dean Sheppard, University of California, San Francisco, USA Enhancement of Anti-Tumor Immunity by Inhibition of TGFbeta Activation by the Integrin alphavbeta8
Sunday, February 23 \| 8:00AM - 11:00AM Progenitor Cells in Tissue Repair and Organ Regeneration This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 3 of 9 Harold A. Chapman, University of California, San Francisco, USA Lung Progenitors in Epithelial Renewal Following Injury
Sunday, February 23 \| 8:00AM - 11:00AM Progenitor Cells in Tissue Repair and Organ Regeneration This session is from Fibrosis and Tissue Repair Room: Salon A/B Coffee Break
Sunday, February 23 \| 8:00AM - 11:00AM Progenitor Cells in Tissue Repair and Organ Regeneration This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 5 of 9 Joseph R. Arron, Genentech, Inc., USA Reprogramming Pathogenic Cells to Promote Tissue Repair
Sunday, February 23 \| 8:00AM - 11:00AM Progenitor Cells in Tissue Repair and Organ Regeneration This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 6 of 9 Chris Cox, Genentech, Inc., USA Short Talk: Interleukin 1 Maintains the Intestinal Stem Cell Compartment during C. rodentium Infection through Grem1+ Stromal Derived R-spondin 3
Sunday, February 23 \| 8:00AM - 11:00AM Progenitor Cells in Tissue Repair and Organ Regeneration This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 7 of 9 Miriam Hohmann, Cedars-Sinai Medical Center, USA Short Talk: Role of the C-C Chemokine Receptor (CCR10) in Mesenchymal Progenitor Cells in IPF
Sunday, February 23 \| 8:00AM - 11:00AM Progenitor Cells in Tissue Repair and Organ Regeneration This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 8 of 9 Wilder Scott, University of British Columbia, Canada Short Talk: ScRNA-seq and scATAC-seq Uncover the Fate and Function of Adult Mesenchymal Progenitors at Homeostasis and during Regeneration
Sunday, February 23 \| 8:00AM - 11:00AM Progenitor Cells in Tissue Repair and Organ Regeneration This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 9 of 9 Farshad Babaeijandaghi, University of British Columbia, Canada Short Talk: CSF1R-Dependent Tissue-Resident and Infiltrating Macrophages Play Distinct Roles in Muscle Regeneration and are Promising Targets to Treat Muscular Dystrophies
Sunday, February 23 \| 11:15AM - 5:00PM On Own for Lunch
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Role of Stromal Cells in Inflammation and Anti-T umor Immunity Room: Salon C Speaker 1 of 9 * Viviana Cremasco, Novartis Institutes for BioMedical Research, USA
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Role of Stromal Cells in Inflammation and Anti-T umor Immunity Room: Salon C Speaker 2 of 9 * Anne Fletcher, Monash University, Australia
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Role of Stromal Cells in Inflammation and Anti-T umor Immunity Room: Salon C Speaker 3 of 9 Hung N. Nguyen, Brigham and Women's Hospital, USA Transcriptional Regulation of Fibroblasts in Inflammation
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Role of Stromal Cells in Inflammation and Anti-T umor Immunity Room: Salon C Speaker 4 of 9 Fumitaka Mizoguchi, Tokyo Medical and Dental University, Japan Gene Expression Profiling of Synovial Fibroblast Subsets Revealed Novel Transcription Factors Driving Their Pathogenic Functions in Rheumatoid Arthritis
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Role of Stromal Cells in Inflammation and Anti-T umor Immunity Room: Salon C Speaker 5 of 9 Maria Steele, Oregon Health & Science University, USA Lymphatic-Mediated Egress of Tumor-Specific CD8+ T Cells Limits Anti-Tumor Immunity in Melanoma
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Role of Stromal Cells in Inflammation and Anti-T umor Immunity Room: Salon C Speaker 6 of 9 Hafsa Munir, University of Cambridge, UK Cancer-Associated Fibroblast-Derived Amyloid ß Drives Neutrophil Extracellular Trap Formation to Promote Tumor Progression
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Role of Stromal Cells in Inflammation and Anti-T umor Immunity Room: Salon C Speaker 7 of 9 Sandra Ring, Kantonsspital St. Gallen, Switzerland IL-33 Provision by Reprogrammed Tumor Fibroblastic Stromal Cells Promotes Local T Cell Activity and Grants Melanoma Eradication
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Role of Stromal Cells in Inflammation and Anti-T umor Immunity Room: Salon C Speaker 8 of 9 Laura Donlin, Hospital for Special Surgery & Weill Cornell Medicine, USA Fibroblast Activation by ‘Pro-Invasive’ Macrophages in Human Autoimmunity
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Role of Stromal Cells in Inflammation and Anti-T umor Immunity Room: Salon C Speaker 9 of 9 Elisabetta Dondi, INSERM, France Chronic Lymphocytic Leukemia Nurse-Like Cells are an Alternative Source of CCL21 Homeostatic Chemokine in Disorganized Lymph Nodes
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Moving Anti-Fibrotic Strategies and Targets to t he Clinic This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 1 of 9 * Edda Fiebiger, Abbvie, USA
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Moving Anti-Fibrotic Strategies and Targets to t he Clinic This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 2 of 9 * Paul J. Yaworsky, Mediar Therapeutics, USA
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Moving Anti-Fibrotic Strategies and Targets to t he Clinic This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 3 of 9 Claude Jourdan Le Saux, University of California, San Francisco, USA Serum Biomarker Responses of Pulmonary Fibrosis Patients after Treatment with the LOXL2/TGFß1 Inhibitor EGCG
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Moving Anti-Fibrotic Strategies and Targets to t he Clinic This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 4 of 9 Guiquan Jia, Genentech, Inc., USA Modulation of a Plasma Cell Signature by Interleukin 6 in Systemic Sclerosis Skin Tissue
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Moving Anti-Fibrotic Strategies and Targets to t he Clinic This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 5 of 9 Juan Juan Marugan, NCATS, National Institutes of Health, USA ML290 Ameliorates Fibrosis in Multiple in vivo Models
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Moving Anti-Fibrotic Strategies and Targets to t he Clinic This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 6 of 9 Alex Peidl, Western University, Canada Therapeutic Peptides Based on CCN3 Treat Systemic Sclerosis in a Mouse Model of the Disease
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Moving Anti-Fibrotic Strategies and Targets to t he Clinic This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 7 of 9 Martin Hausmann, University Hospital Zurich, Switzerland New Therapeutic Approach to Intestinal Fibrosis by Inhibition of pH-Sensing Receptor GPR4-Induced Rho Activation
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Moving Anti-Fibrotic Strategies and Targets to t he Clinic This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 8 of 9 Martin Leduc, Liminal R&D BioSciences Inc., Canada Fezagepras (PBI-4050) Reduces Pulmonary Fibroblast Activation, Proliferation, and AKT/mTORC/4E-BP1 Signaling
Sunday, February 23 \| 2:30PM - 4:30PM Workshop 3: Moving Anti-Fibrotic Strategies and Targets to t he Clinic This session is from Fibrosis and Tissue Repair Room: Salon A/B Speaker 9 of 9 Piotr L. Sklepkiewicz, OncoArendi Therapeutics SA, Poland Chitotriosidase (CHIT1) as a Novel Therapeutic Target in Idiopathic Pulmonary Fibrosis (IPF)
Sunday, February 23 \| 4:30PM - 5:00PM Coffee Available Room: Prefunction
Sunday, February 23 \| 5:00PM - 7:00PM New Directions in Dissecting Stromal Cell Functions (Joint) Room: Salon A/B Speaker 1 of 7 * Burkhard Ludewig, Kantonsspital St. Gallen, Switzerland
Sunday, February 23 \| 5:00PM - 7:00PM New Directions in Dissecting Stromal Cell Functions (Joint) Room: Salon A/B Speaker 2 of 7 * Thomas A. Wynn, Pfizer, USA
Sunday, February 23 \| 5:00PM - 7:00PM New Directions in Dissecting Stromal Cell Functions (Joint) Room: Salon A/B Speaker 3 of 7 Stuart J. Forbes, University of Edinburgh, UK Liver Stem Cells and Tissue Regeneration
Sunday, February 23 \| 5:00PM - 7:00PM New Directions in Dissecting Stromal Cell Functions (Joint) Room: Salon A/B Speaker 4 of 7 Jason G. Cyster, HHMI/University of California, San Francisco, USA Stromal Cells as Orchestrators of Humoral Immunity
Sunday, February 23 \| 5:00PM - 7:00PM New Directions in Dissecting Stromal Cell Functions (Joint) Room: Salon A/B Speaker 5 of 7 Shannon J. Turley, Genentech, Inc., USA Stromal Cells in Cancer Immunology and Immunotherapy
Sunday, February 23 \| 5:00PM - 7:00PM New Directions in Dissecting Stromal Cell Functions (Joint) Room: Salon A/B Speaker 6 of 7 Lesley A. Hill, University of British Columbia, Canada Short Talk: Fate and Function of “Mesenchymal” Progenitors in Liver Regeneration and Fibrosis
Sunday, February 23 \| 5:00PM - 7:00PM New Directions in Dissecting Stromal Cell Functions (Joint) Room: Salon A/B Speaker 7 of 7 Ruth A. Franklin, Yale School of Medicine, USA Short Talk: Environmental Sensing by Fibroblasts Controls Growth Factor Production
Sunday, February 23 \| 7:00PM - 7:15PM Meeting Wrap-Up: Outcomes and Future Directions (Joint) Room: Salon A/B
Sunday, February 23 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Crystal Gardens No registration fees are used to fund alcohol served at this function.
Sunday, February 23 \| 8:00PM - 11:00PM Entertainment Room: Crystal Gardens Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
Monday, February 24 \| 10:24AM - 10:24AM Departure *Session Chair †Invited, not yet responded.