Web Desc
Why So Many Ways to Die? Apoptosis, Necroptosis, Pyroptosis and Beyond
Organizer(s): Karina R. Bortoluci, Vishva M. Dixit and Andreas E. Strasser
Date: November 19 - 23, 2019
Location: Casa Grande Hotel, Guarujá, Sao Paulo, Brazil
Organized in collaboration with the São Paulo Research Foundation (FAPESP)
Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation

Supported by a grant from Genentech
Summary of Meeting:
Cell death is linked to diverse physiological and pathological conditions. In addition to the well-defined apoptosis versus accidental necrosis paradigm, novel processes of programmed cell death, necroptosis and pyroptosis, in particular, have been described over the last years. Our knowledge about the molecular machineries that control these cell death processes has expanded substantially with the discovery of key regulators and effectors, such as the gasdermins, mixed-lineage kinase domain-like protein (MLKL), and receptor-interacting protein (RIP) kinases. We have learned that apoptosis, pyroptosis, necroptosis, ferroptosis, autophagic cell death and other cell death processes are all equipped with individual sets of regulatory and effector molecules but can also share constituents that can interconnect the distinct cell death pathways. Moreover, several alternative cell death programs may operate in any given circumstances with distinct consequences to the immune response and to the development of inflammatory disorders. Last, but not least, cell death may not be the sole or even the major fate/purpose of cells that engage inflammatory cell death pathways. Understanding of the role of the different regulators and effectors of each cell death processes is essential for the development of therapeutic tools for cancer, autoimmune diseases and inflammatory pathologies. Thus, this conference proposes to bring together specialists from diverse areas of cell death research from around world to explore these crucial issues to develop a better understanding of the relative, additive and/or redundant contributions of the distinct cell death pathways in health and disease.
Global Health Travel Award Deadline: July 16 2019
Scholarship Deadline: July 30 2019
Discounted Abstract Deadline: July 18 2019
Abstract Deadline: August 20 2019
Discounted Registration Deadline: September 19 2019
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Bill & Melinda Gates FoundationGenentech, Inc.São Paulo Research Foundation (FAPESP) - Brazil
We gratefully acknowledge additional support for this conference from:
AdipoGen Life Sciences
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.
Donors of $50,000 - $99,999. We are very grateful for this extraordinary commitment to our mission to connect the scientific community and accelerate discoveries that benefit the world community. Special thanks to these organizations for consistent, annual Benefactor-level support.
São Paulo Research Foundation (FAPESP) - Brazil
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Tuesday, November 19 | 4:00PM - 8:00PM
Arrival and Registration
Room: Imperial Ballroom Foyer


Tuesday, November 19 | 6:00PM - 8:00PM
Welcome Mixer
Room: Imperial Ballroom Terrace
No registration fees are used to fund alcohol served at this function.

Wednesday, November 20 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Imperial Ballroom

Speaker 1 of 2
* Karina R. Bortoluci, Federal University of São Paulo, Brazil

Wednesday, November 20 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Imperial Ballroom

Speaker 2 of 2
Kim Newton, Genentech, Inc., USA
The Cut that Makes the Difference – A Caspase-8 Story



Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom

Speaker 1 of 7
* Jonathan C. Kagan, Boston Children's Hospital, USA

Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom

Speaker 2 of 7
Hao Wu, Harvard Medical School, Boston Children's Hospital, USA
Inflammasomes: NLRP3 and Gasdermin D (GSDMD)

Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom


Coffee Break

Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom

Speaker 4 of 7
Veit Hornung, Ludwig-Maximilians-University Munich, Germany
Inflammasome Signaling in the Human System

Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom

Speaker 5 of 7
Daniel Kastner, National Institutes of Health, USA
Inflammasomes in Auto-Inflammatory Diseases

Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom

Speaker 6 of 7
Niklas A. Schmacke, Ludwig-Maximilians-University Munich, Germany
Short Talk: Priming Enables a NEK7-Independent Route of NLRP3 Activation


Wednesday, November 20 | 9:30AM - 12:00PM
Advances in Molecular Control of Cell Death I
Room: Imperial Ballroom

Speaker 7 of 7
Bart Tummers, St. Jude Children's Research Hospital, USA
Short Talk: A Non-Apoptotic Function of Caspase-8 Mediates Inflammation and Blocks the Development of ALPS

Wednesday, November 20 | 12:00PM - 5:00PM
On Own for Lunch


Wednesday, November 20 | 12:00PM - 1:00PM
Poster Setup
Room: Imperial Ballroom


Wednesday, November 20 | 1:00PM - 10:00PM
Poster Viewing
Room: Imperial Ballroom


Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 1 of 8
* Russell E. Vance, University of California, Berkeley, USA

Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 2 of 8
Youssef Aachoui, University of Arkansas for Medical Sciences, USA
Innate Lymphocytes Prime Caspase-11 in Neutrophils to Defend against a Cytosol Invasive Bacterium


Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 3 of 8
Thomas Burke, University of California, Berkeley, USA
Inflammasome-Mediated Antagonism of Type I Interferon Enhances Rickettsia Pathogenesis

Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 4 of 8
Laura Migliari Branco, University of São Paulo, Brazil
Molecular Mechanisms Involved in NAIP/NLRC4 Inflammasome Activation


Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 5 of 8
Alejandro Rodriguez Gama, Stowers Institute for Medical Research, USA
The Inflammasome-Nucleating Interactome Reveals Specificity and Crosstalk in Cell Death Signaling

Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 6 of 8
Lucas Secchim Ribeiro, University of Bonn, Germany
Inflammasome Activation and Pyroptosis Drive the Formation of Nuclear Filaments between Macrophages

Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 7 of 8
Kateryna Shkarina, University of Lausanne, Switzerland
Optogenetic Control of Programmed Cell Death Reveals Differential Responses towards Apoptotic and Necrotic Cells

Wednesday, November 20 | 2:30PM - 4:30PM
Workshop 1: Host Defense
Room: Imperial Ballroom

Speaker 8 of 8
Monica Varela, Leiden University, Netherlands
Mycobacteria Exploit Host Caspase 11 and Gasdermin D Tandem for Phagosome Permeabilization, Macrophage Pyroptosis and Infection Dissemination

Wednesday, November 20 | 4:30PM - 5:00PM
Coffee Available
Room: Imperial Ballroom Terrace


Wednesday, November 20 | 5:00PM - 7:00PM
Advances in Molecular Control of Cell Death II
Room: Imperial Ballroom

Speaker 1 of 6
* Domagoj Vucic, Genentech, Inc., USA

Wednesday, November 20 | 5:00PM - 7:00PM
Advances in Molecular Control of Cell Death II
Room: Imperial Ballroom

Speaker 2 of 6
Feng Shao, National Institute of Biological Sciences, China
Mechanism and Function of Gasdermin-Mediated Pyroptosis

Wednesday, November 20 | 5:00PM - 7:00PM
Advances in Molecular Control of Cell Death II
Room: Imperial Ballroom

Speaker 3 of 6
Eicke Latz, University of Bonn, Germany
Cellular Responses to Pyroptosis

Wednesday, November 20 | 5:00PM - 7:00PM
Advances in Molecular Control of Cell Death II
Room: Imperial Ballroom

Speaker 4 of 6
Oliver Florey, Babraham Institute, UK
Eaten Alive! - Mechanisms and Consequences of Cell Cannibalism

Wednesday, November 20 | 5:00PM - 7:00PM
Advances in Molecular Control of Cell Death II
Room: Imperial Ballroom

Speaker 5 of 6
Catherine L. Day, University of Otago, New Zealand
Short Talk: Regulation of Ubiquitin Transfer by TRAF E3 Ligases


Wednesday, November 20 | 5:00PM - 7:00PM
Advances in Molecular Control of Cell Death II
Room: Imperial Ballroom

Speaker 6 of 6
Megan H. Orzalli, University of Massachusetts Medical School, USA
Short Talk: Apoptotic Caspases Activate Pro-Inflammatory Cell Death Pathways in Barrier Epithelial Cells

Wednesday, November 20 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Imperial Ballroom Terrace
No registration fees are used to fund alcohol served at this function.

Wednesday, November 20 | 7:30PM - 10:00PM
Poster Session 1
Room: Imperial Ballroom


Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 1 of 9
* Gustavo P. Amarante-Mendes, Universidade de São Paulo, Brazil

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 2 of 9
Andreas E. Strasser, Walter and Eliza Hall Institute of Medical Research, Australia
Towards Targeting Mutant p53 for Cancer Therapy

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 3 of 9
Henning Walczak, University College London, Cancer Institute, UK
Cell Death and Ubiquitin in Cancer

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom


Coffee Break

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 5 of 9
Ricardo Weinlich, Hospital Israelita Albert Einstein, Brazil
Necroptosis, Inflammation and Cancer

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 6 of 9
Ruth M. Kluck, Walter and Eliza Hall Institute of Medical Research, Australia
BAK and BAX in Cancer

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 7 of 9
Gabriela Brumatti, Walter and Eliza Hall Institute, Australia
Short Talk: RIPping Leukaemias Apart: The Role of RIP Kinase 1 in Acute Myeloid Leukaemia


Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 8 of 9
Dhyan Chandra, Roswell Park Comprehensive Cancer Center, USA
Short Talk: Novel Nuclear-Mitochondrial Crosstalk Regulates Cell Death and Survival in Cancer

Thursday, November 21 | 8:30AM - 11:45AM
Cell Death and Cancer
Room: Imperial Ballroom

Speaker 9 of 9
Eli Arama, Weizmann Institute of Science, Israel
Short Talk: Parthanatos Steps Out of the Shadows of Cell Death and into the Developmental Spotlight


Thursday, November 21 | 11:45AM - 5:00PM
On Own for Lunch


Thursday, November 21 | 11:45AM - 1:00PM
Poster Setup
Room: Imperial Ballroom


Thursday, November 21 | 1:00PM - 10:00PM
Poster Viewing
Room: Imperial Ballroom


Thursday, November 21 | 4:30PM - 5:00PM
Coffee Available
Room: Imperial Ballroom Terrace


Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 1 of 7
* Kim Newton, Genentech, Inc., USA

Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 2 of 7
Vishva M. Dixit, Genentech, Inc., USA
The Non-Canonical Inflammasome Pathway

Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 3 of 7
Jonathan C. Kagan, Boston Children's Hospital, USA
Regulation of Innate Immunity

Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 4 of 7
John Silke, Walter and Eliza Hall Institute of Medical Research, Australia
Mutations that Prevent Caspase Cleavage of RIPK1 Cause Inflammatory Disease

Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 5 of 7
Konrad Aden, University Hospital Kiel, Germany
Short Talk: XBP-1 Coordinates DNA Damage Induced Stem Cell Repression in the Intestinal Epithelium via p53-Ddit4l-Dependent mTOR Inhibition

Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 6 of 7
Randal Halfmann, Stowers Institute for Medical Research, USA
Short Talk: Waiting to Die: Signalosome Nucleation Kinetically Controls Cell Fate


Thursday, November 21 | 5:00PM - 7:15PM
Consequences of Cell Death
Room: Imperial Ballroom

Speaker 7 of 7
Caitlin Schneider, McGill University, Canada
Short Talk: Migration-Induced Cell Shattering Due to DOCK8 Deficiency Causes a Type-2 Biased T Helper Response

Thursday, November 21 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Imperial Ballroom Terrace
No registration fees are used to fund alcohol served at this function.

Thursday, November 21 | 7:30PM - 10:00PM
Poster Session 2
Room: Imperial Ballroom


Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 1 of 8
* Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 2 of 8
Petr Broz, University of Lausanne, Switzerland
Cell Death during Bacteria Infections

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 3 of 8
Ricardo T. Gazzinelli, Fundação Oswaldo Cruz-CPqRR, Brazil
Caspase 8 Mediates Experimental Cerebral Malaria

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom


Coffee Break

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 5 of 8
Russell E. Vance, University of California, Berkeley, USA
Inflammasome-Dependent Cell Death in Response to Bacterial Pathogens

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 6 of 8
Karina R. Bortoluci, Federal University of São Paulo, Brazil
Inflammasomes: Cell Death, Cytokines and Beyond

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 7 of 8
Katie Deets, University of California, Berkeley, USA
Short Talk: Investigating a Role for the NAIP/NLCR4 Inflammasome in Adaptive T Cell Responses

Friday, November 22 | 8:30AM - 11:30AM
Cell Death and Host Defense I
Room: Imperial Ballroom

Speaker 8 of 8
Sergio Costa Oliveira, Universidade Federal de Minas Gerais, Brazil
Short Talk: Guanylate-Binding Protein 5 Licenses Caspase-11 for Gasdermin-D Mediated Host Resistance to Intracellular Bacterial Infection

Friday, November 22 | 11:30AM - 5:00PM
On Own for Lunch


Friday, November 22 | 11:30AM - 1:00PM
Poster Setup
Room: Imperial Ballroom


Friday, November 22 | 1:00PM - 10:00PM
Poster Viewing
Room: Imperial Ballroom


Friday, November 22 | 4:30PM - 5:00PM
Coffee Available
Room: Imperial Ballroom Terrace


Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 1 of 7
* Ricardo T. Gazzinelli, Fundação Oswaldo Cruz-CPqRR, Brazil

Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 2 of 7
Edward A. Miao, University of North Carolina at Chapel Hill, USA
Infectious Models Reveal a Unique Role for Caspase-7 after Cytotoxic Lymphocyte Attack

Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 3 of 7
Dario S. Zamboni, University of São Paulo, Brazil
Inflammasomes in Host Response to Pathogenic Microbes

Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 4 of 7
Larissa D. Cunha, Ribeirao Preto Medical School, University of Sao Paulo, Brazil
Short Talk: Regulation of Macrophage Function by LC3-Associated Phagocytosis


Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 5 of 7
Marcel Doerflinger, Walter and Eliza Hall Institute, Australia
Short Talk: Functional Overlap of Different Cell Death Pathways Ensures Host Protection against Intracellular Bacterial Pathogens

Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 6 of 7
Antonia R. Bass, University of Pennsylvania, USA
Short Talk: Human Noncanonical Inflammasome Responses to Legionella Pneumophila

Friday, November 22 | 5:00PM - 7:00PM
Cell Death and Host Defense II
Room: Imperial Ballroom

Speaker 7 of 7
Kshiti Meera Phulphagar, Max Planck Institute of Biochemistry, Germany
Short Talk: Quantitative Spatial Proteomics Reveals Specific Nlrp3 and Cell Death Mediated Reprogramming of Essential Cellular Functions and Organelles

Friday, November 22 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Imperial Ballroom Terrace
No registration fees are used to fund alcohol served at this function.

Friday, November 22 | 7:30PM - 10:00PM
Poster Session 3
Room: Imperial Ballroom


Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 1 of 10
* Andreas E. Strasser, Walter and Eliza Hall Institute of Medical Research, Australia

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 2 of 10
Andrew W. Roberts, Walter and Eliza Hall Institute of Medical Research, Australia
Translational and Clinical Updates on Targeting BCL2 and MCL-1

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 3 of 10
Ksenija Slavic Obradovic, Boehringer Ingelheim RCV GmBH & Co KG, Austria
Short Talk: Enabling Cell Death: Genetic Dissection of Cellular Responses to SMAC Mimetic Treatment

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 4 of 10
Opher Shai Kornfeld, Genentech, Inc., USA
Short Talk: IRF2 Transcriptionally Induces GSDMD Expression for Pyroptosis

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom


Coffee Break

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 6 of 10
Domagoj Vucic, Genentech, Inc., USA
Regulation of Inflammatory Cell Death Signaling by RIP Kinases

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 7 of 10
Wenlin Shao, AstraZeneca, USA
Broad Opportunity of Cell Death Agents as Mono- and Combination Therapies in Haematological and Solid Cancers

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 8 of 10
Pedro Elias Marques, KU Leuven, Belgium
Short Talk: Displacement of Necrotic Cell Debris In Vivo by a Chemokine-Based Peptide Dampens Tissue Inflammation

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 9 of 10
Jun Sun, University of Illinois at Chicago, USA
Short Talk: Intestinal Vitamin D Receptor Determines Cell Fate via Apoptosis and Autophagy

Saturday, November 23 | 8:30AM - 11:45AM
Manipulating Cell Death for Therapeutic Intervention
Room: Imperial Ballroom

Speaker 10 of 10
Lynn Wong, University of Zurich, Switzerland
Short Talk: TNFR2 Induced Priming of NLRP3-Inflammasome via RIPK1 Leads to Pyroptosis in XIAP Deficient Cells

Saturday, November 23 | 11:45AM - 5:00PM
On Own for Lunch


Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 1 of 8
* Laura D. Attardi, Stanford University School of Medicine, USA

Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 2 of 8
Silvina Odete Bustos, Instituto do Câncer do Estado de São Paulo, Brazil
A New Imidazacridine Derivate with Antineoplasic Activity in Melanoma


Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 3 of 8
Annette Jacobsen, Walter and Eliza Hall Institute, Australia
Up Close and Personal with the Necroptotic Death Effector, MLKL: Lessons Learned from Mutagenesis Studies

Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 4 of 8
Bruna dos Santos Mendonça, Brazilian National Cancer Institute, Brazil
Nuclear Localization of X-Linked Inhibitor of Apoptosis Protein (XIAP): Impact on Drug Resistance, Cell Growth and Prognosis in Breast Cancer

Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 5 of 8
Ancely F. dos Santos, University of São Paulo, Brazil
Ferroptosis Contributes to MB-PDT Efficacy on Killing Human PDAC Cells

Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 6 of 8
Maria Tanzer, Max Planck Institute of Biochemistry, Germany
Phosphoproteome and Secretome Analysis Reveal Differences between TNF-Induced Apoptosis and Necroptosis

Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 7 of 8
Angelica Beate Winter Boldt, Universidade Federal do Paraná, Brazil
At the Edge of Survival: Genetic Associations for Cell Death in Pemphigus Foliaceus


Saturday, November 23 | 2:30PM - 4:30PM
Workshop 2: Cancer
Room: Imperial Ballroom

Speaker 8 of 8
Mikaela Catherine Coleman, University of Sydney, Australia
Dissecting the Ways to Die: A Single-Cell Assay to Simultaneously Quantify Cell Loss and Discriminate Death Program

Saturday, November 23 | 4:30PM - 5:00PM
Coffee Available
Room: Imperial Ballroom Terrace


Saturday, November 23 | 5:00PM - 5:45PM
Keynote Address
Room: Imperial Ballroom

Speaker 1 of 2
* Vishva M. Dixit, Genentech, Inc., USA

Saturday, November 23 | 5:00PM - 5:45PM
Keynote Address
Room: Imperial Ballroom

Speaker 2 of 2
Shigekazu Nagata, IFReC, Osaka University, Japan
Phosphatidylserine-Dependent Efferocytosis and Entosis

Saturday, November 23 | 5:45PM - 7:15PM
Cell Death in Inflammatory Diseases
Room: Imperial Ballroom

Speaker 1 of 4
* John Silke, Walter and Eliza Hall Institute of Medical Research, Australia

Saturday, November 23 | 5:45PM - 7:15PM
Cell Death in Inflammatory Diseases
Room: Imperial Ballroom

Speaker 2 of 4
Francis Ka-Ming Chan, Duke University, USA
RIPK3 in Anti-Viral Immunity and Tissue Homeostasis

Saturday, November 23 | 5:45PM - 7:15PM
Cell Death in Inflammatory Diseases
Room: Imperial Ballroom

Speaker 3 of 4
Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA
Regulation of Inflammasome Activation and Cell Death

Saturday, November 23 | 5:45PM - 7:15PM
Cell Death in Inflammatory Diseases
Room: Imperial Ballroom

Speaker 4 of 4
Laura D. Attardi, Stanford University School of Medicine, USA
Deconstructing p53 Cellular Responses and Transcriptional Programs in Tumor Suppression and Developmental Syndromes

Saturday, November 23 | 7:15PM - 7:30PM
Meeting Wrap-Up: Outcomes and Future Directions
Room: Imperial Ballroom

Speaker 1 of 1
* Andreas E. Strasser, Walter and Eliza Hall Institute of Medical Research, Australia

Saturday, November 23 | 7:30PM - 8:30PM
Social Hour with Lite Bites
Room: Duque de Caxias/Thereza Cristina
No registration fees are used to fund alcohol served at this function.

Saturday, November 23 | 8:00PM - 11:00PM
Entertainment
Room: Duque de Caxias/Thereza Cristina
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Sunday, November 24 | 10:24AM - 10:24AM
Departure


*Session Chair.