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Sunday, January 23 | 4:00PM - 8:00PM
Registration
Arrival and Registration
Room: Cava Santa Fe


Sunday, January 23 | 6:00PM - 8:00PM
Welcome Mixer

Room: Cava Santa Fe
No registration fees are used to fund alcohol served at this function.

Monday, January 24 | 7:00AM - 8:00AM
Breakfast

Room: Anasazi Ballroom


Monday, January 24 | 7:30AM - 8:00AM
Poster Setup

Room: Anasazi Ballroom


Monday, January 24 | 8:00AM - 7:00PM
Poster Viewing

Room: Anasazi Ballroom


Monday, January 24 | 8:00AM - 9:00AM
Keynote Address
Welcome and Keynote Address
Room: Eldorado Grand Ballroom


Patrick Cramer, Max Planck Institute for Biophysical Chemistry, Germany
Structural Views of Transcription

Monday, January 24 | 9:00AM - 11:45AM
Plenary AM
Celebrating 40 Years of the Enhancer
Room: Eldorado Grand Ballroom


Michael S. Levine, Princeton University, USA
Tethering Elements Jump Start Distal Enhancers during Development

Coffee Break

Emma Farley, University of California, San Diego, USA
Enhancer Grammar

Angela Depace, Harvard Medical School, USA
Gene Regulation during Drosophilia Development

Alistair Boettiger, Stanford University, USA
Short Talk: Cross-TAD-Border Enhancer-Promoter Communication Enabled by Domain Stacking Interactions

† Alexandros Pertsinidis, Memorial Sloan Kettering Cancer Center, USA
Short Talk: Revealing Promoter-Enhancer Communication Mechanisms by High-resolution Single-gene Imaging

Bomyi Lim, University of Pennsylvania, USA
Short Talk: 3D Dynamics of Enhancer-promoter Interactions in Living Drosophila Embryos

Monday, January 24 | 11:45AM - 12:30PM
Lunch

Room: Anasazi Ballroom


Monday, January 24 | 12:00PM - 2:30PM
Posters
Poster Session 1
Room: Anasazi Ballroom


Monday, January 24 | 2:30PM - 4:30PM
Workshop
Workshop


Sudarshan Pinglay, New York University School of Medicine, USA
Synthetic Regulatory Genomics: Megabase Scale Genome Writing to Understand Gene Expression Control

Eric L. Greer, Harvard Medical School, Boston Children's Hospital, USA
Role of Epigenetics in the Evolution of Multicellularity

Reuben A. Saunders, Massachusetts Institute of Technology, USA
Mapping the Genetic Landscape of Complex Transcriptional Phenotypes with Genome-Scale Perturb-Seq

Sandipan Brahma, Fred Hutchinson Cancer Research Center, USA
RNAPII Promoter-Proximal Pausing Modulates BAF (SWI/SNF) Chromatin Binding and Nucleosome Remodeling Dynamics

Jeffrey L. Hansen, Washington University in St. Louis, USA
A Test of the Pioneer Factor Hypothesis

Keiichi Ito, Rockefeller University, USA
Analysis of the Role of MED1 in Adipocyte Formation and Function in Mice

Yolanda Markaki, UCLA, USA
Gene Regulation through RNA-Guided Supramolecular Aggregation: How 100 Xist RNA Molecules Silence an Entire Chromosome

Ariel David Pourmorady, Columbia University, USA
Variable Enhancer Patterning and Activity-Dependent Stability around an Active Olfactory Receptor Gene

Monday, January 24 | 4:30PM - 5:00PM
Coffee Available

Room: Concourse


Monday, January 24 | 5:00PM - 7:00PM
Plenary PM
Gene Regulation at Single Cell Resolution
Room: Eldorado Grand Ballroom


Rickard Sandberg, Karolinska Institutet, Sweden
Following Transcription in Single Cells

Ertugrul M. Ozbudak, Cincinnati Children's Hospital Medical Center, USA
Transcriptional Co-Firing Drives Robust Segmentation of the Vertebrate Body Axis

Alexander van Oudenaarden, Hubrecht Institute, Netherlands
Talk Title to be Announced

Marianne Bauer, Princeton University, USA
Short Talk: Trading Bits in the Readout from a Genetic Network

Amy F. Chen, Stanford University, USA
Short Talk: NEAT-Seq: Simultaneous Profiling of Intra-Nuclear Proteins, Chromatin Accessibility, and Gene Expression in Single Cells

Monday, January 24 | 7:00PM - 7:00PM
On Own for Dinner



Tuesday, January 25 | 7:00AM - 8:00AM
Breakfast

Room: Anasazi Ballroom


Tuesday, January 25 | 8:00AM - 11:15AM
Plenary AM
Mechanisms of Transcription Regulation
Room: Eldorado Grand Ballroom


C. Denise Okafor, Pennsylvania State University, USA
Structural Mechanisms of Nuclear Receptors

Andreas Mayer, Max Planck Institute for Molecular Genetics, Germany
Mechanisms of Transcription Control by BET Family Proteins

Coffee Break

Asifa Akhtar, Max Planck Institute of Immunobiology and Epigenetics, Germany
Role of MOF Histone Acetylation in Development

Edith Heard, European Molecular Biology Laboratory, Germany
Transcriptional Regulation of Gene Silencing during X-Chromosome Inactivation in Mammals

Harmen J. Bussemaker, Columbia University, USA
Short Talk: Probing the DNA Binding Specificity of Transcription Factor Complexes with Deep Sequencing and Biophysically Interpretable Machine Learning

Biswajyoti Sahu, University of Helsinki, Finland
Short Talk: Sequence Determinants of Human Gene Regulatory Elements

Karen G. Cornejo, University of California, Merced, USA
Short Talk: The nBAF (mSWI/SNF) Complex Regulates Activity-induced Neuronal Gene Transcription by Facilitating RNA Polymerase II Elongation

Tuesday, January 25 | 11:15AM - 5:00PM
On Own for Lunch



Tuesday, January 25 | 11:15AM - 1:00PM
Poster Setup

Room: Anasazi Ballroom


Tuesday, January 25 | 1:00PM - 10:00PM
Poster Viewing

Room: Anasazi Ballroom


Tuesday, January 25 | 4:30PM - 5:00PM
Coffee Available

Room: Concourse


Tuesday, January 25 | 5:00PM - 7:15PM
Plenary PM
Gene Regulation through Small Molecules and ASOs
Room: Eldorado Grand Ballroom


Ali Shilatifard, Northwestern University, USA
Principles of Epigenetics and Chromatin in Development and Human Disease

Melissa J. Moore, Moderna Therapeutics, USA
mRNA as Medicine

Adrian R. Krainer, Cold Spring Harbor Laboratory, USA
ASOs to Control Splicing

Eric R. Olson, Syros Pharmaceuticals, USA
Small Molecule Inhibitors of Transcription

Sarah Kohrt, Case Western Reserve University, USA
Short Talk: Androgen Receptor Inverse Agonists in Prostate Cancer

Tuesday, January 25 | 7:15PM - 8:15PM
Social Hour with Lite Bites

Room: Anasazi Ballroom
No registration fees are used to fund alcohol served at this function.

Tuesday, January 25 | 7:30PM - 10:00PM
Posters
Poster Session 2
Room: Anasazi Ballroom


Wednesday, January 26 | 7:00AM - 8:00AM
Breakfast

Room: Anasazi Ballroom


Wednesday, January 26 | 8:00AM - 11:00AM
Plenary AM
Seeing Transcription
Room: Eldorado Grand Ballroom


Ibrahim Cissé, Max Planck Institute of Immunobiology and Epigenetics, Germany
High Resolution Imaging of Pol II Dynamics

Speaker to be Announced

Tineke Lenstra, Netherlands Cancer Institute, Netherlands
A Single-Molecule Understanding of Transcriptional Bursting

Katherine Alexander, University of Pennsylvania, USA
Short Talk: A Speck-Tackular Mode of Gene Activation: Transcription Factors Regulate DNA Association with Nuclear Speckles to Boost Gene Expression

H. Courtney Hodges, Baylor College of Medicine, USA
Short Talk: A Ubiquitous Disordered Protein Interaction Module Orchestrates Transcription Elongation

† Timothee Lionnet, NYU School of Medicine, USA
Short Talk: The Kinetic Landscape of Human Transcription Factors

Wednesday, January 26 | 11:00AM - 5:00PM
On Own for Lunch



Wednesday, January 26 | 4:30PM - 5:00PM
Coffee Available

Room: Concourse


Wednesday, January 26 | 5:00PM - 6:45PM
Plenary PM
Coordinating Transcription and Co-Transcriptional Processes
Room: Eldorado Grand Ballroom


Richard A. Young, Whitehead Institute for Biomedical Research, USA
Nuclear Condensates in Gene Regulation and Disease

Daniel R. Larson, NCI, National Institutes of Health, USA
Direct Observations of Splicing Kinetics in Single Cells

L. Stirling Churchman, Harvard Medical School, USA
Control of Co-Transcriptional Splicing and 3' End Processing

Daisy Castillo-Guzman, University of California, Davis, USA
Short Talk: SF3B1-targeted Splicing Inhibition Triggers Global Alterations in Transcriptional Dynamics and R-Loop Metabolism

Wednesday, January 26 | 6:45PM - 7:00PM
Plenary
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Eldorado Grand Ballroom


Wednesday, January 26 | 7:00PM - 8:00PM
Social Hour with Lite Bites

Room: Anasazi Ballroom
No registration fees are used to fund alcohol served at this function.

Wednesday, January 26 | 8:00PM - 9:00PM
Cash Bar

Room: Anasazi Ballroom


Thursday, January 27 | 8:03AM - 8:03AM
Departure



*Session Chair
†Invited, not yet responded.

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