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Sunday, February 06 | 4:00PM - 8:00PM
Registration
Arrival and Registration
Room: President's Hall Foyer


Sunday, February 06 | 6:00PM - 8:00PM
Welcome Mixer

Room: President's Hall
No registration fees are used to fund alcohol served at this function.

Monday, February 07 | 7:00AM - 8:00AM
Breakfast

Room: Van Horne C/President's Hall


Monday, February 07 | 8:00AM - 9:00AM
Keynote Address
Welcome and Keynote Address
Room: Van Horne A


Ira Mellman, Genentech, Inc., USA
Checkpoint and Immune Exhaustion Overview

Monday, February 07 | 9:00AM - 11:00AM
Plenary AM
Advances in Checkpoint Biology I: Lymphocytes
Room: Van Horne A


E. John Wherry, University of Pennsylvania, USA
PD 1/PD L1 and CD8 T Effectors

Coffee Break

Chen Dong, Tsinghua University, China
Beyond PD 1: Differential Roles for other T Cell Checkpoints (e.g. TIM 1 or TIM 3 or TIGIT)

William H. Robinson, Stanford University School of Medicine, USA
Checkpoints in B Cells

Short Talks Chosen from Abstracts

Monday, February 07 | 9:00AM - 11:15AM
Plenary AM
Antigen Targets
This session is from Cancer Vaccines & Viruses
Room: Van Horne B


Jonathan W. Yewdell, NIAID, National Institutes of Health, USA
Identification of Viral Antigen Targets and Discovery of Novel ORFs

Coffee Break

Michal Bassani-Sternberg, University Hospital of Lausanne, Ludwig Institute for Cancer Research, Switzerland
Mass Spectrometry and Proteogenomics Based Approaches for Antigen Detection

Maxim Artyomov, Washington University in St. Louis, USA
Computational Informatic Approaches for Prediction of Neoantigens

Thorbald van Hall, Leiden University Medical Center, Netherlands
Novel Cancer Antigens in the Setting of TAP Deficiency

Short Talks Chosen from Abstracts


Monday, February 07 | 11:15AM - 5:00PM
On Own for Lunch



Monday, February 07 | 11:15AM - 1:00PM
Poster Setup

Room: Van Horne C/President's Hall


Monday, February 07 | 1:00PM - 10:00PM
Poster Viewing

Room: Van Horne C/President's Hall


Monday, February 07 | 4:30PM - 5:00PM
Coffee Available

Room: Van Horne Foyer


Monday, February 07 | 5:00PM - 7:00PM
Plenary PM
Checkpoints in Autoimmunity: Genetic Insights and Innate Immunity Lineages

Room: Van Horne A


Ferenc A. Scheeren, Leiden University Medical Center, Netherlands
Genetics 1—WGS/GWAS in Checkpoint Autoimmunity

Gulbu Uzel, National Institutes of Health, USA
Genetics 2—Insights from Human Checkpoint Mutations (both Autoimmunity and Immunodeficiency)

Carla V. Rothlin, Yale University, USA
Innate Immune Checkpoints: TAMs

Miriam Merad, Mount Sinai School of Medicine, USA
Myeloid Cell Checkpoints

Short Talk(s) Chosen from Abstracts

Monday, February 07 | 5:00PM - 7:00PM
Plenary PM
Cellular Interactions Critical to Effective Tumor Immunity
This session is from Cancer Vaccines & Viruses
Room: Van Horne B


Jannie Borst, Leiden University, Netherlands
Role of CD4 T Cell Help, and Impact of CD27 Costimulation

Robert D. Schreiber, Washington University School of Medicine, USA
Macrophage Subpopulations in Cancer Immune Response

Nir Hacohen, Massachusetts General Hospital, USA
TCF7 Expression in CD8+ T Cells and Its Role in Cancer Immunotherapy

Short Talks Chosen from Abstracts


Monday, February 07 | 7:00PM - 8:00PM
Social Hour with Lite Bites

Room: Van Horne C/President's Hall
No registration fees are used to fund alcohol served at this function.

Monday, February 07 | 7:30PM - 10:00PM
Posters
Poster Session 1
Room: Van Horne C/President's Hall


Tuesday, February 08 | 7:00AM - 8:00AM
Breakfast

Room: Van Horne C/President's Hall


Tuesday, February 08 | 8:00AM - 11:00AM
Plenary AM
Advances in Checkpoint Biology II: Immune Exhaustion and Immunometabolism

Room: Van Horne A


Rafi Ahmed, Emory University School of Medicine, USA
Immune Exhaustion: Functional and Molecular Definitions in Th and Teff Populations

Jeffrey C. Rathmell, Vanderbilt University, USA
Immune Metabolism in the Tumor Microenvironment and Checkpoint Function

Coffee Break

Luke A. J. O'Neill, Trinity Biomedical Sciences Institute, Ireland
Immune Metabolism in Checkpoint Function 2: Innate

Short Talk(s) Chosen from Abstracts

Tuesday, February 08 | 8:00AM - 11:00AM
Plenary AM
Reprogramming the Microenvironment
This session is from Cancer Vaccines & Viruses
Room: Van Horne B


Valerie Chew, SingHealth, Singapore
The Microenvironments of Hepatitis B Virus(HBV)-Related Hepatocellular Carcinoma

Jennifer Ann Wargo, University of Texas MD Anderson Cancer Center, USA
Microbiome and Cancer Immunotherapy

Garry P. Nolan, Stanford University, USA
Direct Spatial Visualization of Microenvironment Changes with Immunotherapy

Short Talks Chosen from Abstracts


Tuesday, February 08 | 11:00AM - 11:45AM
Panel
Panel Discussion: New Directions in Checkpoint Biology: Major Gaps and Emerging Insights
Room: Van Horne A


Tuesday, February 08 | 11:00AM - 5:00PM
On Own for Lunch



Tuesday, February 08 | 11:00AM - 1:00PM
Poster Setup

Room: Van Horne C/President's Hall


Tuesday, February 08 | 1:00PM - 10:00PM
Poster Viewing

Room: Van Horne C/President's Hall


Tuesday, February 08 | 2:30PM - 4:30PM
Workshop
Workshop 1: Emerging Checkpoints Insights: Basic and Animal Model Studies
Room: Van Horne A


Short Talks Chosen from Abstracts

Tuesday, February 08 | 4:30PM - 5:00PM
Coffee Available

Room: Van Horne Foyer


Tuesday, February 08 | 5:00PM - 7:00PM
Plenary PM
Checkpoints in Autoimmunity: Function and Dysfunction in Disease

Room: Van Horne A


Bali Pulendran, Stanford University School of Medicine, USA
Defining what Good Looks Like: Quantifying Homeostasis and Appropriate Immune Exhaustion as Treatment Goals

Laura Cappelli, Johns Hopkins University, USA
Checkpoint Dysfunction, Disease 1 (e.g. RA or MS)

Kenneth Smith, University of Cambridge, UK
Lymphocyte Exhaustion State in Autoimmune Disease X: Integrating Functional Status across Active Checkpoints

Short Talk(s) Chosen from Abstracts

Tuesday, February 08 | 5:00PM - 7:00PM
Plenary PM
Immune Targeting against Viral Antigens
This session is from Cancer Vaccines & Viruses
Room: Van Horne B


Helen Heslop, Baylor College of Medicine, Houston Methodist Hospital and Texas Childrens, USA
Adoptive Transfer of Virus Specific T Cells

Cornelis J. M. Melief, Leiden University Medical Center & ISA Pharmaceuticals BV, Netherlands
Vaccines Targeting HPV Antigens

Eric Vivier, Aix Marseille University and Inna Pharma, France
Harnessing Natural Killer cell in cancer therapies

Short Talks Chosen from Abstracts


Tuesday, February 08 | 7:00PM - 8:00PM
Social Hour with Lite Bites

Room: Van Horne C/President's Hall
No registration fees are used to fund alcohol served at this function.

Tuesday, February 08 | 7:30PM - 10:00PM
Posters
Poster Session 2
Room: Van Horne C/President's Hall


Wednesday, February 09 | 7:00AM - 8:00AM
Breakfast

Room: Van Horne C/President's Hall


Wednesday, February 09 | 8:00AM - 11:00AM
Plenary AM (JT)
Immunoregulation and Immunosuppression (Joint)
Room: Van Horne A/B


Thomas Gajewski, University of Chicago, USA
The Tumor Microenvironment and Immunotherapy Efficacy

Shannon J. Turley, Genentech, Inc., USA
Stromal Cells in Modulating Anticancer Responses

Coffee Break

† Ozlem Tureci, BioNTech, Germany
Talk Title to be Announced

David A. Hafler, Yale University School of Medicine, USA
Checkpoint Dysfunction in Autoimmune Disease

Short Talks Chosen from Abstracts

Wednesday, February 09 | 11:00AM - 5:00PM
On Own for Lunch



Wednesday, February 09 | 11:00AM - 1:00PM
Poster Setup

Room: Van Horne C/President's Hall


Wednesday, February 09 | 1:00PM - 10:00PM
Poster Viewing

Room: Van Horne C/President's Hall


Wednesday, February 09 | 2:30PM - 4:30PM
Workshop
Workshop 2: Emerging Checkpoints Insights: Translational and Clinic Studies
Room: Van Horne A


Short Talks Chosen from Abstracts

Wednesday, February 09 | 4:30PM - 5:00PM
Coffee Available

Room: Van Horne Foyer


Wednesday, February 09 | 5:00PM - 7:00PM
Plenary PM
Checkpoints Insights from Infectious Diseases and Environmental Triggers

Room: Van Horne A


Georg Lauer, Massachusetts General Hospital, USA
Checkpoint Signaling and Phenotype in Chronic Viral Infections

Mala K. Maini, University College London, UK
Beyond Classical Checkpoints in the Liver Niche

Kevan C. Herold, Yale University, USA
Checkpoint Inhibitor Autoimmunity after Withdrawal of Therapy: Continued Checkpoint Dysfunction or Evidence for Environmental Regulation?

Short Talks Chosen from Abstracts

Wednesday, February 09 | 5:00PM - 7:00PM
Plenary PM
Vaccines in Cancer and Other Non Infectious Syndromes
This session is from Cancer Vaccines & Viruses
Room: Van Horne B


Gerald P. Linette, University of Pennsylvania, USA
Dendritic-Based Targeting of Tumor Neoantigens

Ugur Sahin, BioNTech AG, Germany
Individualized RNA-Based Cancer Vaccines

Catherine J. Wu, Dana-Farber Cancer Institute, USA
SLPs for Personal Neoantigen-Targeting Vaccines

Short Talks Chosen from Abstracts


Wednesday, February 09 | 7:15PM - 8:15PM
Social Hour with Lite Bites

Room: Van Horne C/President's Hall
No registration fees are used to fund alcohol served at this function.

Wednesday, February 09 | 7:30PM - 10:00PM
Posters
Poster Session 3
Room: Van Horne C/President's Hall


Thursday, February 10 | 7:00AM - 8:00AM
Breakfast

Room: Van Horne C/President's Hall


Thursday, February 10 | 8:00AM - 11:00AM
Plenary AM
Checkpoints in Oncology—Treatment Effectiveness, Include CAR T, States of Immune Exhaustion in I O, and Combo Approaches

Room: Van Horne A


Charles Drake, Janssen, USA
Talk Title to be Announced

Maria E. Suarez-Almazor, University of Texas MD Anderson Cancer Center, USA
Oncology Adverse Events Treatments

Coffee Break

Crystal L. Mackall, Stanford University, USA
Checkpoints in CAR-T Therapies

Arlene H. Sharpe, Harvard Medical School, USA
Using Genetics to Define Novel Combo Checkpoints

Short Talk(s) Chosen from Abstracts

Thursday, February 10 | 8:00AM - 11:00AM
Plenary AM
Novel Combinatorial Approaches
This session is from Cancer Vaccines & Viruses
Room: Van Horne B


Padmanee Sharma, University of Texas MD Anderson Cancer Center, USA
Role of ICOS in Checkpoint Blocking Therapy

Nina Bhardwaj, Icahn School of Medicine at Mount Sinai, USA
Combination of Flt3L and Vaccine

Coffee Break

Irving L. Weissman, Stanford University, USA
Normal and Neoplastic Stem Cells

Short Talks Chosen from Abstracts


Thursday, February 10 | 5:00PM - 6:30PM
Plenary PM
Emerging Clinical Insights into Checkpoint Contributions to Autoimmunity

Room: Van Horne A


Javid Moslehi, UCSF School of Medicine, USA
I-O Checkpoint Antagonists Associated Autoimmunity: Distinct Disease Phenotypes (Similarities and Differences to Spontaneous Autoimmunity) Associated with Current Monotherapy and Combo Therapy Approaches

Alexandra-Chloé Villani, Broad Institute of MIT and Harvard, USA
New Views on ‘Traditional’ Autoimmune Disease Informed by Checkpoint Antagonist Therapy

David M. Lee, Janssen Pharmaceutical Companies of Johnson & Johnson, USA
Checkpoint Agonists 1 (Disease/Checkpoint)

Thursday, February 10 | 5:00PM - 6:30PM
Plenary PM
Combination Therapy with Oncolytic Virus and Viral Delivery Systems
This session is from Cancer Vaccines & Viruses

Room: Van Horne B


John C. Bell, Ottawa Hospital Research Institute, Canada
Oncolytic Viruses: Multiplex Cancer Therapeutics

Kevin Harrington, Institute of Cancer Research, UK
Physical & Pharmacological Modulation of Oncolytic Virotherapy

Alan J. Korman, Vir Biotechnology, Inc., USA
Virus as an Antigen Delivery System

Short Talks Chosen from Abstracts


Thursday, February 10 | 6:30PM - 7:00PM
Panel
Panel Discussion: Targeting Checkpoints in Human Disease: Gaps for Translation and Opportunities Ahead
Room: Van Horne A


Thursday, February 10 | 6:45PM - 7:00PM
Plenary
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
This session is from Cancer Vaccines & Viruses
Room: Van Horne B


Thursday, February 10 | 7:00PM - 7:15PM
Plenary
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Van Horne A


Thursday, February 10 | 7:15PM - 8:15PM
Social Hour with Lite Bites

Room: Van Horne C/President's Hall


Thursday, February 10 | 8:00PM - 9:00PM
Cash Bar

Room: Van Horne C/President's Hall


Friday, February 11 | 8:29AM - 8:29AM
Departure



*Session Chair
†Invited, not yet responded.

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