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Sunday, January 16 | 4:00PM - 8:00PM
Registration
Arrival and Registration
Room: Van Horne Foyer


Sunday, January 16 | 6:00PM - 8:00PM
Welcome Mixer

Room: Van Horne Foyer
No registration fees are used to fund alcohol served at this function.

Monday, January 17 | 7:00AM - 8:00AM
Breakfast

Room: Van Horne C/President's Hall


Monday, January 17 | 8:00AM - 9:00AM
Keynote Address (JT)
Welcome and Keynote Address (Joint)
Room: Van Horne A/B


Jeffrey C. Rathmell, Vanderbilt University, USA
Metabolic Checkpoints in the Tumor Microenvironment and Inflammation

Monday, January 17 | 9:00AM - 11:15AM
Plenary AM (JT)
Metabolic Regulation of the Anti-Cancer Immune Response (Joint)

Room: Van Horne A/B


Erika L. Pearce, Johns Hopkins University, USA
Metabolic Regulation of Immune Cells in Cancer

Coffee Break

Lydia Lynch, Harvard Medical School, USA
Interplay between Obesity, Immune Cells, and Cancer

Marcia C. Haigis, Harvard Medical School, USA
The Role of Metabolites in Anti-Tumor Immunity

Murad R. Mamedov, UCSF / Gladstone, USA
Short Talk: CRISPR Screens Reveal AMPK-Dependent Metabolic Regulation of Cancer Cell Interactions with ?d T Cells

Meng-Ju Wu, Massachusetts General Hospital, USA
Short Talk: Mutant-IDH1 Promotes Immunoevasion and Tumor Maintenance in Cholangiocarcinoma

Monday, January 17 | 11:15AM - 5:00PM
On Own for Lunch



Monday, January 17 | 11:15AM - 1:00PM
Poster Setup

Room: Van Horne C/President's Hall


Monday, January 17 | 1:00PM - 10:00PM
Poster Viewing

Room: Van Horne C/President's Hall


Monday, January 17 | 2:30PM - 4:30PM
Workshop
Workshop 1: Fundamentals of Immunometabolism
Room: Van Horne A


Michael Berger, Hebrew University, Israel
Enhanced Methionine Cycle Suppresses Naïve CD8 T-Cell Maturation

Scott Widenmaier, University of Saskatchewan, Canada
Diet-Induced Hepatic Cholesterol Toxicity is Co-Counteracted by NRF1 and NRF2

Simon D. O'Shaughnessy, Trinity Biomedical Science Institute, Ireland
Proteomic Analysis of Metabolism of in vivo Conventional Murine Dendritic Cells

Bruno Guigas, Leiden University Medical Center, Netherlands
LKB1 Signaling in Dendritic Cells Controls Whole-Body Metabolic Homeostasis by Limiting T Helper 17 Priming

Carla Alicia Jaeger-Ruckstuhl, Fred Hutchinson Cancer Research Center, USA
CD27 Co-Stimulation Regulates Naïve T Cell Fate Early During Priming and Improves Immunotherapeutic Potential of CAR-T Cells

Rosa Menjivar, University of Michigan, USA
Depletion of Arginase 1 in Myeloid Cells Alters the Pancreatic Cancer Tumor Microenvironment

Andrew R. Patterson, Vanderbilt University Medical Center, USA
Identifying Metabolic Regulators of CD4+ T cells Using Mendelian Disease

Gloria Asantewaa, University of Rochester, USA
The Interplay of Glutathione and Lipid Homeostasis in vivo

Monday, January 17 | 2:30PM - 4:30PM
Workshop
Workshop 1
This session is from Tumor Metabolism
Room: Van Horne B


Liron Bar-Peled, Massachusetts General Hospital/Harvard Medical School, USA
Identification of Compartmentalized ROS vulnerabilities in Cancer

Christopher Chidley, Harvard Medical School, USA
Systems-Wide Characterization of Amino Acid Transport

Brooke M. Emerling, Sanford Burnham Prebys, USA
Exploiting Peroxisome-Mitochondria Interplay by Targeting Phosphoinositide Kinases

Mingqi Han, UCLA, USA
Three-Dimensional Imaging and Analysis of Mitochondrial Structure and Function in Lung Cancer

Fabricio Loayza-Puch, German Cancer Research Center, Germany
Dual Ribosome Profiling Uncovers Metabolic Limitations in Distinct Cellular Populations of the Tumor Microenvironment

Marco Zocchi, University of Rochester Medical Center, USA
Glutathione Catabolism may be a Critical Amino Acid Source for Cancer Cell Survival

Yanxiang (Jessie) Guo, Rutgers University, USA
Autophagy Inhibition Sensitizes Lkb1-Deficient Kras-Driven Lung Tumors to MEK Inhibitor Trametinib via Ferroptotic Cell Death


Monday, January 17 | 4:30PM - 5:00PM
Coffee Available

Room: Van Horne Foyer


Monday, January 17 | 5:00PM - 7:00PM
Plenary PM
Metabolic Reprogramming for Improved Immunotherapy
Room: Van Horne A


Susan M. Kaech, The Salk Institute, USA
Immunometabolism of Long-Term Immunity

Ping-Chih Ho, University of Lausanne, Switzerland
Fat Fuels Tumor Tregs

Russell G. Jones, Van Andel Research Institute, USA
How metabolic fuels regulate T cell function

Sagar P. Bapat, University of California, San Francisco, USA
Short Talk: Correcting Altered Immunological Responses in Obesity Restores Efficacy of Targeted Biologic Therapy for Inflammatory Disease

Hanna S. Hong, University of Michigan, USA
Short Talk: OXPHOS Promotes Apoptotic Resistance and Persistence in TH17 Cells

Monday, January 17 | 5:00PM - 7:00PM
Plenary PM
Metabolic Regulation by Kinases
This session is from Tumor Metabolism
Room: Van Horne B


Reuben J. Shaw, The Salk Institute for Biological Studies, USA
AMP Kinase

Brendan D. Manning, Harvard School of Public Health, USA
Metabolic Effectors of mTOR Signalling

John Blenis, Weill Cornell Medical College, USA
Metabolic Regulation of Metastasis

Anni Zhang, University of British Columbia, Canada
Short Talk: Insulin Receptor Signaling in Pancreatic Acinar Cells Contributes to Pancreatic Cancer Development

Mike Uretz John Oliphant, Harvard Medical School, USA
Short Talk: Investigating the Role of SLC7A5 in Metabolic Reprogramming of Therapy Resistant ER+ Breast Cancer


Monday, January 17 | 7:00PM - 8:00PM
Social Hour with Lite Bites

Room: Van Horne C/President's Hall
No registration fees are used to fund alcohol served at this function.

Monday, January 17 | 7:30PM - 10:00PM
Posters
Poster Session 1
Room: Van Horne C/President's Hall


Tuesday, January 18 | 7:00AM - 8:00AM
Breakfast

Room: Van Horne C/President's Hall


Tuesday, January 18 | 8:00AM - 11:00AM
Plenary AM (JT)
Amino Acid Metabolism and Nutrient Balance (Joint)
Room: Van Horne A/B


Craig B. Thompson, Memorial Sloan Kettering Cancer Center, USA
Identifying Metabolic Limitations in Cancer

Karen H. Vousden, Francis Crick Institute, UK
Serine Metabolism and Cancer Development

Coffee Break

Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA
Metabolic Interactions between Cancer and Host

Hongbo Chi, St. Jude Children's Research Hospital, USA
Nutrient Sensing and Signaling in Immune Function

Konrad Aden, University Hospital Kiel, Germany
Short Talk: Tryptophan Degradation as Actionable Immunometabolic Target in Chronic Inflammatory Diseases

Juan J. Apiz Saab, University of Chicago, USA
Short Talk: Myeloid-Derived Arginase Depletes Microenvironmental Arginine in PDAC Tumors and Leads to Activation of Arginine de novo Biosynthesis in Cancer Cells

Tuesday, January 18 | 11:00AM - 5:00PM
On Own for Lunch



Tuesday, January 18 | 11:00AM - 1:00PM
Poster Setup

Room: Van Horne C/President's Hall


Tuesday, January 18 | 1:00PM - 10:00PM
Poster Viewing

Room: Van Horne C/President's Hall


Tuesday, January 18 | 4:30PM - 5:00PM
Coffee Available

Room: Van Horne Foyer


Tuesday, January 18 | 5:00PM - 7:00PM
Plenary PM
Microbial Metabolites, Nutrients and Cancer
Room: Van Horne A


Dan R. Littman, HHMI/New York University School of Medicine, USA
Host and Microbial Metabolites in Th17 Immunity

Janelle S. Ayres, The Salk Institute for Biological Studies, USA
Microbiota Metabolites in Health and Disease

Mark A. Febbraio, Monash Institute of Pharmaceutical Sciences, Australia
Role of the Gut Liver Axis in NASH Driven Cancer

Sean Spencer, Stanford University, USA
Short Talk: Fermented Food-Derived Bacterial Metabolites Participate in a Transkingdom Metabolic Network to Regulate Intestinal Immunity and Diet Induced Obesity

Tuesday, January 18 | 5:00PM - 7:00PM
Plenary PM
Metabolic Control of Differentiation and Immune Escape
This session is from Tumor Metabolism
Room: Van Horne B


Lydia Finley, Memorial Sloan Kettering Cancer Center, USA
Metabolic Control of Cell Fate Decisions

Jared Rutter, University of Utah, USA
Pyruvate Metabolism and Cellular Decisions

Alec Kimmelman, New York University Langone Medical Center, USA
Metabolic Control of Immune Tolerance in Cancer

Wilbert P. Vermeij, Princess Máxima Center for Pediatric Oncology and Oncode Institute, Netherlands
Short Talk: Delaying Accelerated Aging and Chemotherapy-Induced Toxicity by Nutritional Interventions

Mara Mennuni, Karolinska Institutet, Sweden
Short Talk: Metabolic Resistance to Therapeutic Inhibition of mtDNA Gene Expression in Cancer Cells


Tuesday, January 18 | 7:00PM - 8:00PM
Social Hour with Lite Bites

Room: Van Horne C/President's Hall
No registration fees are used to fund alcohol served at this function.

Tuesday, January 18 | 7:30PM - 10:00PM
Posters
Poster Session 2
Room: Van Horne C/President's Hall


Wednesday, January 19 | 7:00AM - 8:00AM
Breakfast

Room: Van Horne C/President's Hall


Wednesday, January 19 | 8:00AM - 11:00AM
Plenary AM
Immune Interactions with Systemic and Tissue Metabolism
Room: Van Horne A


Catherine Postic, INSERM Institut Cochin, France
Nutrient Sensing in Liver through the OGT Enzyme

† Douglas R. Green, St. Jude Children's Research Hospital, USA
Talk Title to be Announced

Giuseppe Matarese, Università degli Studi di Napoli Federico II, Italy
Systemic Metabolism, Leptin and Tregs

Coffee Break

Zuri Sullivan, Harvard University, USA
Intestinal Response to Nutrient Sensing

Miguel Reina Campos, University of California, San Diego, USA
Common Metabolic Adaptations Empower CD8 T Cell Tissue Residency and Antitumor Immunity

Stefanie K. Wculek, Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, Spain
Short Talk: OXPHOS Targeting Differentially Impacts Tissue Macrophages Depending on their Homeostatic Function

Santiago Valle Torres, Peter Doherty Institute, Australia
Short Talk: Inflammation Dependent Differentiation of Two Distinct Adipose Tissue Treg Populations Shape Systemic Metabolism

Andrea Keller, Ohio State University, USA
Short Talk: Intestinal Gasdermin C Expression is Dependent on Nutrient Status and Immune Environment

Wednesday, January 19 | 8:00AM - 11:00AM
Plenary AM
Redox Metabolism
This session is from Tumor Metabolism
Room: Van Horne B


Gina DeNicola, Moffitt Cancer Center, USA
Cysteine Metabolism in Cancer

Navdeep S. Chandel, Northwestern University, USA
Mitochondrial Metabolism in Cancer

Coffee Break

Christina Towers, The Salk Institute for Biological Studies, USA
Circumventing Autophagy Inhibition in Cancer Cells

Thales Papagiannakopoulos, New York University School of Medicine, USA
KEAP1/NRF2 Pathway in Cancer

Madeleine Louisa Hart, Fred Hutch Cancer Center, USA
Short Talk: Mitochondrial Redox Adaptations are Essential for Aspartate Synthesis in SDH Deficient Cancer Cells

Rebecca Louise Westbrook, University of Birmimgham, UK
Short Talk: Proline Synthesis through PYCR1 is Required to Support Cancer Cell Proliferation and Survival in Oxygen-Limiting Conditions

Myriam Cerezo-Magaña, Lund University, Sweden
Short Talk: Hypoxic Induction of Exosome Uptake through Proteoglycan Dependent Endocytosis Fuels the Lipid Droplet Phenotype in Glioma


Wednesday, January 19 | 11:00AM - 5:00PM
On Own for Lunch



Wednesday, January 19 | 11:00AM - 1:00PM
Poster Setup

Room: Van Horne C/President's Hall


Wednesday, January 19 | 1:00PM - 10:00PM
Poster Viewing

Room: Van Horne C/President's Hall


Wednesday, January 19 | 4:30PM - 5:00PM
Coffee Available

Room: Van Horne Foyer


Wednesday, January 19 | 5:00PM - 7:00PM
Plenary PM (JT)
Tumor Interaction with Host and Microbes (Joint)
Room: Van Horne A/B


Yasmine Belkaid, NIAID, National Institutes of Health, USA
Nutritional Control of Immunity

Eileen P. White, Rutgers Cancer Institute of New Jersey, USA
Immune Response Regulation by Autophagy in Cancer

Joshua D. Rabinowitz, Princeton University, USA
NADPH and Fat Sources in Tissues and Tumors

Julian J. Lum, BC Cancer, Canada
Short Talk: Duality of Metabolites in T cell Antitumor Function

Oliver Jonas, Brigham & Women's Hospital, USA
Short Talk: In Situ Manipulation of Metabolic Pathways to Examine Nutrient Competition Between Immune Cells and Malignant Cells in Tumors

Wednesday, January 19 | 7:00PM - 8:00PM
Social Hour with Lite Bites

Room: Van Horne C/President's Hall
No registration fees are used to fund alcohol served at this function.

Wednesday, January 19 | 7:30PM - 10:00PM
Posters
Poster Session 3
Room: Van Horne C/President's Hall


Thursday, January 20 | 7:00AM - 8:00AM
Breakfast

Room: Van Horne C/President's Hall


Thursday, January 20 | 8:00AM - 11:00AM
Plenary AM
High-Fat Diet, Lipids and Cancer
Room: Van Horne A


Salvador Aznar Benitah, ICREA and Institute for Research in Biomedicine, Spain
Targeting Metastasis through Lipid Metabolism

Rachel J. Perry, Yale University, USA
Breaking the Link between Obesity and Cancer

Coffee Break

Weiping Zou, University of Michigan, USA
Improving Metabolic Responses to Immunotherapy

Semir Beyaz, Cold Spring Harbor Laboratory, USA
Dietary Control of Tumor Metabolism

Jacqueline A. Turner, University of Colorado Anschutz School of Medicine, USA
Short Talk: Lipid Modulation of CD8 T Cell Immunosurveillance, Metabolism, and Anti-tumor Immunity

Nathalie M. Schmidt, University College London, UK
Short Talk: Targeting Cholesterol Metabolism as a Novel Immune Checkpoint in Viral Infections and Cancer

Thursday, January 20 | 8:00AM - 11:00AM
Plenary AM
Targeting Metabolism
This session is from Tumor Metabolism
Room: Van Horne B


Ralph J. DeBerardinis, University of Texas Southwestern Medical Center, USA
Metabolic Dependencies in Tumors in Humans

Mariia Yuneva, Francis Crick Institute, UK
Identifying Metabolic Vulnerabilities and Flexibilities of Tumours

Coffee Break

Ayelet Erez, Weizmann Institute of Science, Israel
Targeting the Urea Cycle

Barbara S. Fox, Rheos Medicines, USA
Leveraging Immunometabolism for the Treatment of Autoimmune Disease

Brooks P. Leitner, Yale University, USA
Short Talk: Systemic Nutrient Partitioning and Tumor Immunometabolic Reprogramming Underlie Exercise’s Anti-Cancer Effects

Philippa Burns, University of Illinois at Chicago, USA
Short Talk: Investigating the Response of Breast Cancer Cells to Serine Starvation

Milan R. Savani, University of Texas Southwestern Medical Center, USA
Short Talk: Divergent Pyrimidine and Purine Nucleotide Synthesis Programs Underlie Sensitivity to De Novo Pyrimidine Synthesis Inhibition in IDH1 Mutant Glioma


Thursday, January 20 | 11:00AM - 5:00PM
On Own for Lunch



Thursday, January 20 | 2:30PM - 4:30PM
Workshop
Workshop 2: Translational Immunometabolism in Disease
Room: Van Horne A


Lydia Dyck, Max-Delbrück Centrum for Molecular Medicine, Germany
Obesity Suppresses Anti-Tumour Immunity

Petya Apostolova, Johns Hopkins University, USA
Targeting the Creatine Metabolism Crosstalk Between Malignant Cells and T Cells for the Treatment of Acute Myeloid Leukemia

Jackie Bader, Vanderbilt University Medical Center, USA
Tumor Associated Macrophages Contribute to the Obesity Paradox of Immune Checkpoint Therapy

Peter J. Siska, University Hospital Regensburg, Germany
Metabolic Imbalance of T Cells in COVID-19 is Hallmarked by Basigin and Mitigated by Dexamethasone

† Alexandra L. Kuhlmann, Yale, USA
Metabolic Adaptation of Tissue-Resident Macrophages in Cancer

Soo-Youl Kim, National Cancer Center, South Korea
Blocking Obesity or Fatty Acid Oxidation Suggests a Potential New Therapeutic Approach for Pancreatic Cancer

Eva Tsaousidou, Harvard T.H. Chan School of Public Health, USA
TIRR Suppression Mediates a Cancer-Preventive Tolerable p53 Activation with Metabolic Side Effects

Thursday, January 20 | 2:30PM - 4:30PM
Workshop
Workshop 2
This session is from Tumor Metabolism
Room: Van Horne B


Mark Basik, McGill University, Canada
Targeting Lipid Droplets in Chemoresistant Triple Negative Breast Cancer

Rebekah Brooks, University of Pennsylvania, USA
PBAF-associated Circadian lncRNA ADIRF-AS1 Regulates Renal Clear Cell Tumorigenesis

Victoria da Silva Diz, Rutgers University, USA
A Novel and Highly Effective Mitochondrial Uncoupling Drug in T-cell Leukemia

Jiangbin Ye, Stanford University, USA
Deciphering the Warburg Effect: Redox is the Key to Tumor differentiation

Gregory S. Ducker, University of Utah, USA
Altered Phosphatidylcholine Metabolism Creates a Targetable Vulnerability in a ß-catenin Driven Zebrafish Model of Hepatocellular Carcinoma

Aleksandra Filipovska, University of Western Australia, Australia
An RNA-binding Protein Variant Predisposes to Prostate Cancer by Altering Immunometabolism via Mitochondria

Laura C. Kim, University of Pennsylvania, USA
Competition for Arginine Between Tumor and Immune Cells in HCC

Amber Kleckner, Univ of Maryland, Baltimore, USA
Associations Between Mitochondrial Function and Cancer-Related Fatigue among Patients Undergoing Chemotherapy


Thursday, January 20 | 4:30PM - 5:00PM
Coffee Available

Room: Van Horne Foyer


Thursday, January 20 | 5:00PM - 6:45PM
Plenary PM
Frontiers in Immunometabolism
Room: Van Horne A


Donal Brennan, University College Dublin, Ireland
Intentional Weight Loss to Treat Cancer

Ido Amit, Weizmann Institute, Israel
The Power of ONE: Immunology in the Age of Single Cell Genomics

Luke A. J. O'Neill, Trinity Biomedical Sciences Institute, Ireland
Warburg and Mitochondrial Metabolism in Inflammation

Dirk Brenner, Luxembourg Institute of Health, Luxembourg
Short Talk: Regulatory T cell Metabolism: cROSsroads Between Glutathione, Serine and Immune Tolerance

Thursday, January 20 | 5:00PM - 6:45PM
Plenary PM
Metabolic Vulnerabilities
This session is from Tumor Metabolism
Room: Van Horne B


Kivanc Birsoy, Rockefeller University, USA
Metabolic Dependencies of Cancer Cells in vivo

Heather Christofk, University of California, Los Angeles, USA
Metabolic Transitions in Cancer

Roberto Zoncu, University of California, Berkeley, USA
Regulation of Cancer Metabolism by the Lysosome


Thursday, January 20 | 6:45PM - 7:00PM
Plenary
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Van Horne A


Thursday, January 20 | 6:45PM - 7:00PM
Plenary
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
This session is from Tumor Metabolism
Room: Van Horne B


Thursday, January 20 | 7:00PM - 8:00PM
Social Hour with Lite Bites

Room: Van Horne C/President's Hall
No registration fees are used to fund alcohol served at this function.

Thursday, January 20 | 8:00PM - 9:00PM
Cash Bar

Room: Van Horne C/President's Hall


Friday, January 21 | 8:29AM - 8:29AM
Departure



*Session Chair
†Invited, not yet responded.

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