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Sunday, June 05 | 4:00PM - 8:00PM
Registration
Arrival and Registration
Room: Longs Peak Foyer


Sunday, June 05 | 6:00PM - 8:00PM
Welcome Mixer

Room: Longs Peak Foyer
No registration fees are used to fund alcohol served at this function.

Monday, June 06 | 7:00AM - 8:00AM
Breakfast

Room: Colorado Rockies Ballroom


Monday, June 06 | 8:00AM - 9:30AM
Keynote Address (JT)
Welcome and Keynote Session (Joint)
Room: Grays/Longs Peaks


Rudolph E. Tanzi, Massachusetts General Hospital, USA
New Insights into Pathogenesis and Therapeutics Options in Alzheimer’s Disease

Thomas C. Südhof, Stanford School of Medicine, USA
Synapse Biology in Alzheimer’s Disease

Coffee Break

Monday, June 06 | 9:50AM - 11:15AM
Plenary AM (JT)
Genetics of Neuro-Immune Interactions (Joint)
Room: Grays/Longs Peaks


Speaker to be Announced

† Speaker to be Announced

Alison Goate, Icahn School of Medicine at Mount Sinai, USA
Alzheimer’s Disease Susceptibility Alleles Implicate Endolysosomal Function in Microglia

Short Talk(s) Chosen from Abstracts

Monday, June 06 | 11:15AM - 5:00PM
On Own for Lunch



Monday, June 06 | 11:15AM - 1:00PM
Poster Setup

Room: Colorado Rockies Ballroom


Monday, June 06 | 1:00PM - 10:00PM
Poster Viewing

Room: Colorado Rockies Ballroom


Monday, June 06 | 2:30PM - 4:30PM
Workshop
Workshop 1: Imaging of the CNS in Health and Disease
This session is from Neuro-Immune Interactions
Room: Longs Peak


Short Talks Chosen from Abstracts


Monday, June 06 | 4:30PM - 5:00PM
Coffee Available

Room: Longs Peak Foyer


Monday, June 06 | 5:00PM - 7:00PM
Plenary PM
Synaptic Mechanisms and Molecular Events
Room: Grays Peak


Pietro V. De Camilli, Yale University School of Medicine, USA
Synaptic Membrane Endocytosis

Morgan H. Sheng, Broad Institute, USA
Mechanisms of Synapse Loss in Neurodegenerative Disease

Maria Grazia Spillantini, University of Cambridge, UK
Synaptic Dysfunction in Parkinson’s Disease

Volker Haucke, Leibniz Forschungsinstitut für Molekulare Pharmakologie, Germany
Synaptic Vesicle Exo-Endocytosis and Reformation

Short Talk(s) Chosen from Abstracts

Monday, June 06 | 5:00PM - 7:00PM
Plenary PM
Understanding Immune Receptors in the CNS
This session is from Neuro-Immune Interactions
Room: Longs Peak


Greg E. Lemke, The Salk Institute for Biological Studies, USA
TAM Receptor Regulation of Neurodegenerative Disease

Shilpa Sambashivan, Nura Bio, USA
Intracellular Receptors for NAD in Neurodegeneration

Marco Colonna, Washington University School of Medicine, USA
ITAM Signaling in Neurodegeneration

Short Talks Chosen from Abstracts


Monday, June 06 | 7:00PM - 8:00PM
Social Hour with Lite Bites

Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Monday, June 06 | 7:30PM - 10:00PM
Posters
Poster Session 1
Room: Colorado Rockies Ballroom


Tuesday, June 07 | 7:00AM - 8:00AM
Breakfast

Room: Colorado Rockies Ballroom


Tuesday, June 07 | 7:30AM - 8:00AM
Poster Setup

Room: Colorado Rockies Ballroom


Tuesday, June 07 | 8:00AM - 7:00PM
Poster Viewing

Room: Colorado Rockies Ballroom


Tuesday, June 07 | 8:00AM - 11:00AM
Plenary AM
Autophagy and Disease
Room: Grays Peak


Ivan Dikic, Goethe University Medical School, Germany
ER-phagy: From Molecular Principles to Pathogenesis of Neuropathies

Xinnan Wang, Stanford University School of Medicine, USA
Redox Mechanisms in Aging and Neurodegeneration.

Coffee Break

Myriam Heiman, Massachusetts Institute of Technology, USA
Genome-Wide in vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and Mutant Huntingtin Toxicity

Ai Yamamoto, Columbia University, USA
Selective Autophagy in the CNS

Short Talk(s) Chosen from Abstracts

Tuesday, June 07 | 8:00AM - 11:00AM
Plenary AM
Microglia, Other Glial Cells and Macrophages in Neurodegenerative Diseases
This session is from Neuro-Immune Interactions

Room: Longs Peak


Michael T. Heneka, German Center for Neurodegenerative Diseases, Germany
Detrimental Effects of Inflammasome Activation and ASC Spec as a Plaque Nucleating Event in Alzheimer’s Disease

Rosa C. Paolicelli, University of Lausanne, Switzerland
Metabolic Control of Microglial Function

Coffee Break

Marco Prinz, University of Freiburg, Germany
Brain Macrophages in Neurodegenerative Diseases

Dorothy Schafer, University of Massachusetts Chan Medical School, USA
Microglial Regulation of Synaptic Connectivity in Demyelinating Disease

Short Talks Chosen from Abstracts


Tuesday, June 07 | 11:00AM - 12:30PM
Lunch

Room: Colorado Rockies Ballroom


Tuesday, June 07 | 12:00PM - 2:30PM
Posters
Poster Session 2
Room: Colorado Rockies Ballroom


Tuesday, June 07 | 2:30PM - 4:30PM
Workshop
Workshop 2: IPSC and Organoids for the Study of Neurodegeneration
This session is from Neuro-Immune Interactions
Room: Longs Peak


Short Talks Chosen from Abstracts


Tuesday, June 07 | 4:30PM - 5:00PM
Coffee Available

Room: Longs Peak Foyer


Tuesday, June 07 | 5:00PM - 7:00PM
Plenary PM
Endolysosomal Dysfunction in Neurodegeneration
Room: Grays Peak


Dimitri Krainc, Northwestern University, USA
Convergence of Mitochondrial and Lysosomal Dysfunction

Ralph A. Nixon, New York University, Langone Medical Center, USA
Defective Endolysosomal Function in Disease

Roberto Zoncu, University of California, Berkeley, USA
mTOR and Lysosomes in Nutrient Sensing and Growth Control

Short Talk(s) Chosen from Abstracts

Tuesday, June 07 | 5:00PM - 7:00PM
Plenary PM
The Role of Brain Immune System in Shaping the CNS Connectivity
This session is from Neuro-Immune Interactions

Room: Longs Peak


Jun R. Huh, Harvard Medical School, USA
Impact of Gut Bacteria in Neurodevelopmental Abnormalities

Katerina Akassoglou, University of California, San Francisco, USA
Microglia Regulation of Brain Network Hyperexcitability.

Anne Schaefer, Icahn School of Medicine at Mount Sinai, USA
Control of Neuronal Activity by Microglia

Short Talks Chosen from Abstracts


Tuesday, June 07 | 7:00PM - 7:00PM
On Own for Dinner



Wednesday, June 08 | 7:00AM - 8:00AM
Breakfast

Room: Colorado Rockies Ballroom


Wednesday, June 08 | 8:00AM - 11:00AM
Plenary AM
Mitochondrial Defects in Neurodegeneration
Room: Grays Peak


Dalton James Surmeier, Northwestern University, USA
Bioenergetic Determinants of Selective Neuronal Vulnerability in Parkinson’s Disease

Richard J. Youle, NINDS, National Institutes of Health, USA
Neuroinflammation Stemming from Mitochondrial DAMPs Linked to Parkinson’s Disease Genes and Mitophagy Defects

Coffee Break

Yvette C. Wong, Northwestern University, USA
Mitochondria-Lysosome Contact Sites: Roles and Regulation in Homeostasis and Neurodegenerative Diseases

Short Talk(s) Chosen from Abstracts

Wednesday, June 08 | 8:00AM - 11:00AM
Plenary AM
Application of Next Generation Technologies to Profile Neuro Immune Interactions
This session is from Neuro-Immune Interactions

Room: Longs Peak


Frederic Geissmann, Memorial Sloan Kettering Cancer Center, USA
Mosaicism in the Central Nervous System and Neurodegeneration

Li-Huei Tsai, Massachusetts Institute of Technology, USA
The Use of Induced Pluripotent Stem Cells to Model Alzheimer’s Disease

Coffee Break

Ido Amit, Weizmann Institute, Israel
The Power of ONE: Immunology in the Age of Single Cell Genomics

Christopher K. Glass, University of California, San Diego, USA
Decoding Microglia Enhancers in Health and Disease

Short Talks Chosen from Abstracts


Wednesday, June 08 | 11:00AM - 5:00PM
On Own for Lunch



Wednesday, June 08 | 11:00AM - 1:00PM
Poster Setup

Room: Colorado Rockies Ballroom


Wednesday, June 08 | 1:00PM - 10:00PM
Poster Viewing

Room: Colorado Rockies Ballroom


Wednesday, June 08 | 2:30PM - 4:30PM
Workshop
Workshop: Cellular Pathways Driving Disease
Room: Grays Peak


Short Talks Chosen from Abstracts

Wednesday, June 08 | 4:30PM - 5:00PM
Coffee Available

Room: Longs Peak Foyer


Wednesday, June 08 | 5:00PM - 7:00PM
Plenary PM
Neuronal Pathways in Disease
Room: Grays Peak


David M. Holtzman, Washington University, USA
Innate Immunity, ApoE, and Neurodegeneration

Virginia M. Y. Lee, University of Pennsylvania School of Medicine, USA
Pathogenic Neuronal Mechanisms in Parkinson’s and Alzheimer’s

Martin Kampmann, University of California, San Francisco, USA
CRISPR-based Functional Genomics for Neurological Disease

Danielle Posthuma, Vrije Universiteit Amsterdam, Netherlands
BrainScapes

Short Talk(s) Chosen from Abstracts

Wednesday, June 08 | 5:00PM - 7:00PM
Plenary PM
Brain Immune System in Neuroinflammation
This session is from Neuro-Immune Interactions
Room: Longs Peak


Menna Clatworthy, University of Cambridge, UK
Plasma Cells in the Meninges

Malu G. Tansey, University of Florida, USA
Immune Function and Inflammation in Parkinson's Disease

Francisco J. Quintana, Harvard Medical School and the Broad Institute of MIT and Harvard, USA
Impact of Aryl Hydrocarbon Receptor in Multiple Sclerosis

Short Talks Chosen from Abstracts


Wednesday, June 08 | 7:00PM - 8:00PM
Social Hour with Lite Bites

Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Wednesday, June 08 | 7:30PM - 10:00PM
Posters
Poster Session 3
Room: Colorado Rockies Ballroom


Thursday, June 09 | 7:00AM - 8:00AM
Breakfast

Room: Colorado Rockies Ballroom


Thursday, June 09 | 8:00AM - 11:00AM
Plenary AM
Translational Considerations in Neurodegenerative Research
Room: Grays Peak


Alfred W. Sandrock Jr., Biogen, Inc., USA
Introduction “Challenges of going from Bench to Bedside in Neurology”

Richard Hargreaves, Bristol-Myers Squibb, USA
Moving Drug Candidates from Drug Discovery into First-in-Human Studies

Coffee Break

Carole Ho, Denali Therapeutics Inc., USA
Phase 2 Trial Design Considerations: How to Achieve Proof of Biology and Proof of Efficacy

Short Talk(s) Chosen from Abstracts

Thursday, June 09 | 8:00AM - 11:00AM
Plenary AM
Blood Brain Barrier (BBB), Glymphatics and Lymphatics
This session is from Neuro-Immune Interactions
Room: Longs Peak


Jonathan Kipnis, Washington University School of Medicine, USA
Meningeal Sinuses and Lymphatics in the Epicenter of CNS Immune Surveillance

Zsuzsanna Fabry, University of Wisconsin, USA
How does the Meningeal Lymphatics Respond to Neuroinflammation in Autoimmunity, Infection, and Trauma?

Coffee Break

Berislav Zlokovic, University of Southern California, USA
Pericytes Play an Important Role in Maintaining the BBB

Chenghua Gu, Harvard Medical School, USA
Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis in BBB

Short Talks Chosen from Abstracts


Thursday, June 09 | 11:00AM - 5:00PM
On Own for Lunch



Thursday, June 09 | 2:30PM - 4:30PM
Workshop
Workshop 3: Immunotherapy of Neurodegeneration
This session is from Neuro-Immune Interactions
Room: Longs Peak


Short Talks Chosen from Abstracts


Thursday, June 09 | 4:30PM - 5:00PM
Coffee Available

Room: Longs Peak Foyer


Thursday, June 09 | 5:00PM - 6:45PM
Plenary PM
Future Directions for Therapeutics
Room: Grays Peak


Anabella Villalobos, Biogen, USA
Therapeutic Modalities for CNS

C. Frank Bennett, Ionis Pharmaceuticals, Inc., USA
Oligonucleotide-based Therapeutic Approaches

† Jana Mitchell, Insitro, USA
Talk Title to be Announced

Short Talk(s) Chosen from Abstracts

Thursday, June 09 | 5:00PM - 6:45PM
Plenary PM
Aging, Metabolism and Neurodegeneration
This session is from Neuro-Immune Interactions
Room: Longs Peak


Katrin Andreasson, Stanford University, USA
Myeloid Cell Metabolism in Aging

Tony Wyss-Coray, Stanford University School of Medicine, USA
Systemic Regulation of Brain Aging

Douglas R. Green, St. Jude Children's Research Hospital, USA
Autophagy in Alzheimer’s Disease

Short Talks Chosen from Abstracts


Thursday, June 09 | 6:45PM - 7:00PM
Plenary
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Grays Peak


Thursday, June 09 | 6:45PM - 7:00PM
Plenary
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
This session is from Neuro-Immune Interactions
Room: Longs Peak


Thursday, June 09 | 7:00PM - 8:00PM
Social Hour with Lite Bites

Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Thursday, June 09 | 8:00PM - 9:00PM
Cash Bar

Room: Colorado Rockies Ballroom


Friday, June 10 | 10:29AM - 10:29AM
Departure



*Session Chair
†Invited, not yet responded.

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