Molecular and Cellular Biology of Leukocyte Regulatory Receptors
Organizer(s): John R. Ortaldo and Lewis L. LanierDate: March 17 - 22, 2002
Location: Granlibakken Tahoe, Tahoe City, CA, USA
The goal of this conference is to highlight progress in both molecular and cellular biology for a novel class of Leukocyte Regulatory Receptors (LRR) that are involved in positive and negative regulation of immune cell function. LRR contain either ITIM- or ITAM-sequences in the cytoplasmic domains and include membrane receptors of the Ig- and C-type lectin superfamily. Their expression is broad since family members are found on a variety of leukocytes (LAIR), including natural killer and T cells (KIR, Ly-49, CD94, gp49, NKG2), B (PIR) cells, mast cells (gp49, MAFA) and monocyte-macrophage-dendritic cells (ILT, LIR, PIR). This meeting will bring together leaders whose studies include expression, structure, signal transduction and biological functions of LRR, and their interactions with ligands, including tumor cells, viral and bacterial pathogens.
Discounted Abstract Deadline: November 16 2001
Discounted Registration Deadline: January 17 2002