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Thursday, January 10 | 4:00PM - 7:00PM
Registration
Room: Shavano Peak Foyer


Thursday, January 10 | 6:15PM - 7:15PM
Welcome
Room: Shavano Peak Foyer


Thursday, January 10 | 7:15PM - 7:30PM
Orientation
Room: Crestone/Red Cloud


Thursday, January 10 | 7:30PM - 8:30PM
Keynote Address (Joint). Sponsored in part by OSI Pharmaceu
ticals, Inc.
Room: Crestone/Red Cloud

Speaker 1 of 2
* Jeffrey M. Friedman, Rockefeller University, USA

Thursday, January 10 | 7:30PM - 8:30PM
Keynote Address (Joint). Sponsored in part by OSI Pharmaceu
ticals, Inc.
Room: Crestone/Red Cloud

Speaker 2 of 2
Robert G. Roeder, Rockefeller University, USA
Regulation of Transcription in Mammalian Cells: Complexities and Challenges

Friday, January 11 | 7:00AM - 8:00AM
Breakfast
Room: Longs/Quandary


Friday, January 11 | 8:00AM - 11:00AM
Central vs. Peripheral Signals Regulating Appetite and Gluco
se Metabolism (Joint)

Room: Crestone/Red Cloud

Speaker 1 of 5
Jeffrey M. Friedman, Rockefeller University, USA
Leptin

Friday, January 11 | 8:00AM - 11:00AM
Central vs. Peripheral Signals Regulating Appetite and Gluco
se Metabolism (Joint)

Room: Crestone/Red Cloud

Speaker 2 of 5
Hiroaki Masuzaki, Beth Israel Deaconess Medical Center, USA
Glucocorticoid Reactivation in Adipose Tissue and the Pathogenesis of Visceral Fat Obesity and Metabolic Syndrome


Friday, January 11 | 8:00AM - 11:00AM
Central vs. Peripheral Signals Regulating Appetite and Gluco
se Metabolism (Joint)

Room: Crestone/Red Cloud

Speaker 3 of 5
Jeffrey Flier, Harvard University, USA
Novel pathways for regulating body weight and insulin resistance.

Friday, January 11 | 8:00AM - 11:00AM
Central vs. Peripheral Signals Regulating Appetite and Gluco
se Metabolism (Joint)

Room: Crestone/Red Cloud

Speaker 4 of 5
Roger D. Cone, University of Michigan, USA
Actions of Gut Peptides on Hypothalamus and Brainstem

Friday, January 11 | 8:00AM - 11:00AM
Central vs. Peripheral Signals Regulating Appetite and Gluco
se Metabolism (Joint)

Room: Crestone/Red Cloud

Speaker 5 of 5
* Luciano Rossetti, Merck Research Laboratories, USA
A Tale of Fat and Sugar

Friday, January 11 | 9:20AM - 9:40AM
Coffee Break
Room: Shavano Peak Foyer/Lobby


Friday, January 11 | 11:00AM - 1:00PM
Poster Setup
Room: Grays Peak 1-3


Friday, January 11 | 1:00PM - 10:30PM
Poster Viewing
Room: Grays Peak 1-3


Friday, January 11 | 4:00PM - 4:30PM
Coffee & Snacks Available
Room: Shavano Peak Foyer/Lobby


Friday, January 11 | 4:30PM - 6:30PM
Central Signaling II
Room: Crestone/Red Cloud

Speaker 1 of 6
* Jeffrey Flier, Harvard University, USA

Friday, January 11 | 4:30PM - 6:30PM
Central Signaling II
Room: Crestone/Red Cloud

Speaker 2 of 6
Eleftheria Maratos-Flier, Beth Israel Deaconess Medical Center, USA
The multiple roles of melanin-concentrating hormone in regulating energy balance.

Friday, January 11 | 4:30PM - 6:30PM
Central Signaling II
Room: Crestone/Red Cloud

Speaker 3 of 6
Joel K. Elmquist, University of Texas Southwestern Medical Center, USA
CNS Pathways Underlying the Coordinated Responses to Metabolic Perturbations

Friday, January 11 | 4:30PM - 6:30PM
Central Signaling II
Room: Crestone/Red Cloud

Speaker 4 of 6
George Kunos, NIAAA, National Institutes of Health, USA
Short Talk: Endocannabinoids and the Control of Food and Ethanol Intake

Friday, January 11 | 4:30PM - 6:30PM
Central Signaling II
Room: Crestone/Red Cloud

Speaker 5 of 6
Jürgen Wess, NIDDK, National Institutes of Health, USA
Short Talk: Muscarinic Acetylcholine Receptors in Body Weight Control

Friday, January 11 | 4:30PM - 6:30PM
Central Signaling II
Room: Crestone/Red Cloud

Speaker 6 of 6
Kendra K. Bence, Pfizer Inc., USA
Short Talk: Regulation of Leptin Signaling by PTP1B

Friday, January 11 | 4:30PM - 6:30PM
Lipid Mediators and Protein Kinases in Hormone Action
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 1 of 5
* † David E. Moller, Eli Lilly and Company, USA


Friday, January 11 | 4:30PM - 6:30PM
Lipid Mediators and Protein Kinases in Hormone Action
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 2 of 5
Morris J. Birnbaum, Pfizer Inc., USA
Akt/PKB as a Critical Determinant of Cell Growth and Metabolism


Friday, January 11 | 4:30PM - 6:30PM
Lipid Mediators and Protein Kinases in Hormone Action
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 3 of 5
Masato Kasuga, National Center for Global Health and Medicine, Japan
Downstream Effectors of PI3- Kinase


Friday, January 11 | 4:30PM - 6:30PM
Lipid Mediators and Protein Kinases in Hormone Action
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 4 of 5
Michael P. Czech, University of Massachusetts Medical School, USA
Insulin Signaling to Molecular Motors


Friday, January 11 | 4:30PM - 6:30PM
Lipid Mediators and Protein Kinases in Hormone Action
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 5 of 5
Emmanuel Van Obberghen, INSERM U145, France
Modulators of Insulin Action


Friday, January 11 | 8:30PM - 10:30PM
Poster Session 1
Room: Grays Peak 1-3


Friday, January 11 | 8:30PM - 9:30PM
Social Hour
Room: Grays Peak 1-3


Friday, January 11 | 9:30PM - 10:30PM
Cash Bar
Room: Grays Peak 1-3


Saturday, January 12 | 7:00AM - 8:00AM
Breakfast
Room: Longs/Quandary


Saturday, January 12 | 8:00AM - 11:00AM
Adipogenesis
Room: Crestone/Red Cloud

Speaker 1 of 5
M. Daniel Lane, Johns Hopkins University, USA
Role of the Cell Cycle in the Adipocyte Differentiation Program

Saturday, January 12 | 8:00AM - 11:00AM
Adipogenesis
Room: Crestone/Red Cloud

Speaker 2 of 5
Stephen R. Farmer, Boston University School of Medicine, USA
Transcriptional Control of Adipogenesis

Saturday, January 12 | 8:00AM - 11:00AM
Adipogenesis
Room: Crestone/Red Cloud

Speaker 3 of 5
Karsten Kristiansen, University of Copenhagen, Denmark
The Retinoblastoma Protein and Adipocyte Differentiation

Saturday, January 12 | 8:00AM - 11:00AM
Adipogenesis
Room: Crestone/Red Cloud

Speaker 4 of 5
Ormond A. MacDougald, University of Michigan, USA
Role of Wnt signaling in Adipocyte Biology

Saturday, January 12 | 8:00AM - 11:00AM
Adipogenesis
Room: Crestone/Red Cloud

Speaker 5 of 5
Jean Sébastien Saulnier-Blache, INSERM U317, France
Short Talk: Secretion of Lysophosphatidic Acid by Adipocytes: Metabolic Origin and Biological Consequences

Saturday, January 12 | 8:00AM - 11:00AM
Early Signaling Events in Insulin Action. Sponsored in part
by Novo Nordisk A/S.
This session is from Diabetes Mellitus

Room: Shavano/Torreys

Speaker 1 of 5
* Pierre De Meyts, Hagedorn Research Institute, Novo Nordisk A/S, Denmark


Saturday, January 12 | 8:00AM - 11:00AM
Early Signaling Events in Insulin Action. Sponsored in part
by Novo Nordisk A/S.
This session is from Diabetes Mellitus

Room: Shavano/Torreys

Speaker 2 of 5
Morris F. White, Boston Children's Hospital, Harvard Medical School, USA
IRS-Proteins and the Common Path to Diabetes


Saturday, January 12 | 8:00AM - 11:00AM
Early Signaling Events in Insulin Action. Sponsored in part
by Novo Nordisk A/S.
This session is from Diabetes Mellitus

Room: Shavano/Torreys

Speaker 3 of 5
Alan R. Saltiel, University of California, San Diego, USA
Spatial Compartments in Insulin Action


Saturday, January 12 | 8:00AM - 11:00AM
Early Signaling Events in Insulin Action. Sponsored in part
by Novo Nordisk A/S.
This session is from Diabetes Mellitus

Room: Shavano/Torreys

Speaker 4 of 5
Steven E. Shoelson, Harvard Medical School, Joslin Diabetes Center, USA
Relationships Between Inflammation, IKKbeta, and Insulin Resistance in Type 2 Diabetes


Saturday, January 12 | 8:00AM - 11:00AM
Early Signaling Events in Insulin Action. Sponsored in part
by Novo Nordisk A/S.
This session is from Diabetes Mellitus

Room: Shavano/Torreys

Speaker 5 of 5
Michael R. Jirousek, Frequency Therapeutics, USA
Recent Advances in PTP1B Inhibitor Design and as a Therapeutic Approach to Treat Type 2 Diabetes


Saturday, January 12 | 9:20AM - 9:40AM
Coffee Break
Room: Shavano Peak Foyer/Lobby


Saturday, January 12 | 11:00AM - 1:00PM
Poster Setup
Room: Grays Peak 1-3


Saturday, January 12 | 1:00PM - 10:30PM
Poster Viewing
Room: Grays Peak 1-3


Saturday, January 12 | 4:00PM - 4:30PM
Coffee & Snacks Available
Room: Shavano Peak Foyer/Lobby


Saturday, January 12 | 4:30PM - 6:30PM
Crosstalk Between Tissues in Metabolic Regulation (Joint).
Sponsored in part by Affinity BioReagents, Inc.

Room: Crestone/Red Cloud

Speaker 1 of 5
* E. Dale Abel, University of Iowa, Carver College of Medicine, USA

Saturday, January 12 | 4:30PM - 6:30PM
Crosstalk Between Tissues in Metabolic Regulation (Joint).
Sponsored in part by Affinity BioReagents, Inc.

Room: Crestone/Red Cloud

Speaker 2 of 5
C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA
Dissecting Insulin Action and Gene Expression Using Knockout Mouse Models

Saturday, January 12 | 4:30PM - 6:30PM
Crosstalk Between Tissues in Metabolic Regulation (Joint).
Sponsored in part by Affinity BioReagents, Inc.

Room: Crestone/Red Cloud

Speaker 3 of 5
Gerald I. Shulman, Yale University School of Medicine, USA
Mechanism of Fat Induced Insulin Resistance

Saturday, January 12 | 4:30PM - 6:30PM
Crosstalk Between Tissues in Metabolic Regulation (Joint).
Sponsored in part by Affinity BioReagents, Inc.

Room: Crestone/Red Cloud

Speaker 4 of 5
Philipp E. Scherer, University of Texas Southwestern Medical Center, USA
Adiponectin and Resistin - Adipokines Modulating Insulin Signaling

Saturday, January 12 | 4:30PM - 6:30PM
Crosstalk Between Tissues in Metabolic Regulation (Joint).
Sponsored in part by Affinity BioReagents, Inc.

Room: Crestone/Red Cloud

Speaker 5 of 5
Se-Jin Kim, Johns Hopkins University, USA
Regulation of Muscle Mass by Myostatin

Saturday, January 12 | 8:30PM - 10:30PM
Poster Session 2
Room: Grays Peak 1-3


Saturday, January 12 | 8:30PM - 9:30PM
Social Hour
Room: Grays Peak 1-3


Saturday, January 12 | 9:30PM - 10:30PM
Cash Bar
Room: Grays Peak 1-3


Sunday, January 13 | 7:00AM - 8:00AM
Breakfast
Room: Longs/Quandary


Sunday, January 13 | 8:00AM - 11:00AM
Adipose-Derived Regulators of Metabolism and Energy Expendit
ure (Joint)

Room: Crestone/Red Cloud

Speaker 1 of 4
Gökhan S. Hotamisligil, Harvard School of Public Health, USA
Molecular Mechanisms of Insulin Resistance in Adipocytes

Sunday, January 13 | 8:00AM - 11:00AM
Adipose-Derived Regulators of Metabolism and Energy Expendit
ure (Joint)

Room: Crestone/Red Cloud

Speaker 2 of 4
Mitchell A. Lazar, Perelman School of Medicine, University of Pennsylvania, USA
Update on Resistin

Sunday, January 13 | 8:00AM - 11:00AM
Adipose-Derived Regulators of Metabolism and Energy Expendit
ure (Joint)

Room: Crestone/Red Cloud

Speaker 3 of 4
* Barbara B. Kahn, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Leptin Activates AMP-Activated Protein Kinase in Muscle Through Central and Peripheral Mechanisms: Implications for Fatty Acid Metabolism


Sunday, January 13 | 8:00AM - 11:00AM
Adipose-Derived Regulators of Metabolism and Energy Expendit
ure (Joint)

Room: Crestone/Red Cloud

Speaker 4 of 4
Sven Enerbäck, University of Gothenburg, Sweden
FOXC2 is a Winged Helix Gene that Counteracts Obesity, Hypertriglyceridemia and Diet Induced Insulin Resistance

Sunday, January 13 | 9:20AM - 9:40AM
Coffee Break
Room: Shavano Peak Foyer/Lobby


Sunday, January 13 | 11:00AM - 1:00PM
Poster Setup
Room: Grays Peak 1-3


Sunday, January 13 | 1:00PM - 10:30PM
Poster Viewing
Room: Grays Peak 1-3


Sunday, January 13 | 4:00PM - 4:30PM
Coffee & Snacks Available
Room: Shavano Peak Foyer/Lobby


Sunday, January 13 | 4:30PM - 6:30PM
Energy Expenditure and Thermogenesis
Room: Crestone/Red Cloud

Speaker 1 of 5
* Bradford B. Lowell, Beth Israel Deaconess Medical Center, USA

Sunday, January 13 | 4:30PM - 6:30PM
Energy Expenditure and Thermogenesis
Room: Crestone/Red Cloud

Speaker 2 of 5
Daniel Ricquier, Centre National de la Recherche Scientifique, France
Uncoupling Proteins: Functional Roles

Sunday, January 13 | 4:30PM - 6:30PM
Energy Expenditure and Thermogenesis
Room: Crestone/Red Cloud

Speaker 3 of 5
Jan Nedergaard, Stockholm University, Sweden
Adrenergic Thermogenesis

Sunday, January 13 | 4:30PM - 6:30PM
Energy Expenditure and Thermogenesis
Room: Crestone/Red Cloud

Speaker 4 of 5
Leslie P. Kozak, Polish Academy of Sciences, Poland
UCP1-Independent Mechanisms of Thermogenesis and Body Weight Regulation

Sunday, January 13 | 4:30PM - 6:30PM
Energy Expenditure and Thermogenesis
Room: Crestone/Red Cloud

Speaker 5 of 5
Sheila Collins, Vanderbilt University Medical Center, USA
Short Talk: Control of UCP1 Expression by PKA/p38 MAPK and PGC1

Sunday, January 13 | 4:30PM - 6:30PM
Vesicle Trafficking and Glucose Transport
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 1 of 5
* Paul F. Pilch, Boston University School of Medicine, USA


Sunday, January 13 | 4:30PM - 6:30PM
Vesicle Trafficking and Glucose Transport
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 2 of 5
Jeffrey E. Pessin, Albert Einstein College of Medicine, USA
The Role of TC10 and Actin in the Insulin Regulation of GLUT4 Translocation


Sunday, January 13 | 4:30PM - 6:30PM
Vesicle Trafficking and Glucose Transport
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 3 of 5
Silvia Corvera, University of Massachusetts Medical School, USA
Analysis of GLUT4 Trafficking by Ultrafast Microscopy


Sunday, January 13 | 4:30PM - 6:30PM
Vesicle Trafficking and Glucose Transport
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 4 of 5
Amira Klip, Hospital for Sick Children, Canada
Regulation of GLUT4 Activity by Insulin in Muscle and Adipose Cells


Sunday, January 13 | 4:30PM - 6:30PM
Vesicle Trafficking and Glucose Transport
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 5 of 5
Yannick Le Marchand-Brustel, INSERM, France
Role of Rab4 and its Effectors in Glut4 Traffic


Sunday, January 13 | 8:30PM - 10:30PM
Poster Session 3
Room: Grays Peak 1-3


Sunday, January 13 | 8:30PM - 9:30PM
Social Hour
Room: Grays Peak 1-3


Sunday, January 13 | 9:30PM - 10:30PM
Cash Bar
Room: Grays Peak 1-3


Monday, January 14 | 7:00AM - 8:00AM
Breakfast
Room: Longs/Quandary


Monday, January 14 | 8:00AM - 11:00AM
Lipodystrophy and Adipocyte Function
Room: Crestone/Red Cloud

Speaker 1 of 6
* Phillip Gorden, National Institutes of Health, USA

Monday, January 14 | 8:00AM - 11:00AM
Lipodystrophy and Adipocyte Function
Room: Crestone/Red Cloud

Speaker 2 of 6
Constantine Londos, National Institutes of Health, USA
Perilipin: A Key Component of the Adipocyte Lipolytic Reaction

Monday, January 14 | 8:00AM - 11:00AM
Lipodystrophy and Adipocyte Function
Room: Crestone/Red Cloud

Speaker 3 of 6
Jocelyne Magré, INSERM, France
Molecular Basis of Generalized and Partial Lipodystrophy

Monday, January 14 | 8:00AM - 11:00AM
Lipodystrophy and Adipocyte Function
Room: Crestone/Red Cloud

Speaker 4 of 6
Marc L. Reitman, NIDDK, National Institutes of Health, USA
The Physiology of Lipoatrophic Mice: Role of Leptin, Liver PPARgamma, and Genetic Background

Monday, January 14 | 8:00AM - 11:00AM
Lipodystrophy and Adipocyte Function
Room: Crestone/Red Cloud

Speaker 5 of 6
Karen Reue, University of California, Los Angeles, USA
Short Talk: The Role of Lipin in Adipogenesis and Lipodystrophy

Monday, January 14 | 8:00AM - 11:00AM
Lipodystrophy and Adipocyte Function
Room: Crestone/Red Cloud

Speaker 6 of 6
Rudolf Zechner, University of Graz, Austria
Resistance to Diet Induced Obesity in Mice that Lack Lipoprotein Lipase in Adipose Tissue

Monday, January 14 | 8:00AM - 11:00AM
Regulation of Glycogen, Protein and Lipid Metabolism
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 1 of 4
* † André Marette, Laval University Hospital Research Center, Canada


Monday, January 14 | 8:00AM - 11:00AM
Regulation of Glycogen, Protein and Lipid Metabolism
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 2 of 4
John C. Lawrence, University of Virginia Health System, USA
mTOR Signaling in Insulin Action


Monday, January 14 | 8:00AM - 11:00AM
Regulation of Glycogen, Protein and Lipid Metabolism
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 3 of 4
Christopher B. Newgard, Duke University Medical Center, USA
Spatial Organization and Regulation of Hepatic Glucose Metabolism


Monday, January 14 | 8:00AM - 11:00AM
Regulation of Glycogen, Protein and Lipid Metabolism
This session is from Diabetes Mellitus
Room: Shavano/Torreys

Speaker 4 of 4
Takashi Kadowaki, University of Tokyo, Japan
The Role of Adiponectin in Insulin Action and Inaction


Monday, January 14 | 9:20AM - 9:40AM
Coffee Break
Room: Shavano Peak Foyer/Lobby


Monday, January 14 | 11:00AM - 1:00PM
Poster Setup
Room: Grays Peak 1-3


Monday, January 14 | 1:00PM - 10:30PM
Poster Viewing
Room: Grays Peak 1-3


Monday, January 14 | 4:00PM - 4:30PM
Coffee & Snacks Available
Room: Shavano Peak Foyer/Lobby


Monday, January 14 | 4:30PM - 6:30PM
Regulation of Gene Expression by Hormones and Nutrients (Joi
nt)

Room: Crestone/Red Cloud

Speaker 1 of 4
* Barry Marc Forman, City of Hope, USA

Monday, January 14 | 4:30PM - 6:30PM
Regulation of Gene Expression by Hormones and Nutrients (Joi
nt)

Room: Crestone/Red Cloud

Speaker 2 of 4
Domenico Accili, Columbia University, USA
Forkhead Proteins in Insulin Action

Monday, January 14 | 4:30PM - 6:30PM
Regulation of Gene Expression by Hormones and Nutrients (Joi
nt)

Room: Crestone/Red Cloud

Speaker 3 of 4
Bruce M. Spiegelman, Harvard Medical School, USA
Control of Energy Homeostasis and Glucose Metabolism Through a PGC-1, Regulated Transcriptional Coactivater

Monday, January 14 | 4:30PM - 6:30PM
Regulation of Gene Expression by Hormones and Nutrients (Joi
nt)

Room: Crestone/Red Cloud

Speaker 4 of 4
Bradford B. Lowell, Beth Israel Deaconess Medical Center, USA
UCP2 and UCP3: Regulators of Intracellular Energy Metabolism

Monday, January 14 | 8:30PM - 10:30PM
Poster Session 4
Room: Grays Peak 1-3


Monday, January 14 | 8:30PM - 9:30PM
Social Hour
Room: Grays Peak 1-3


Monday, January 14 | 9:30PM - 10:30PM
Cash Bar
Room: Grays Peak 1-3


Tuesday, January 15 | 7:00AM - 8:00AM
Breakfast
Room: Longs/Quandary


Tuesday, January 15 | 8:00AM - 11:00AM
Genetics of Diabetes and Obesity (Joint)
Room: Crestone/Red Cloud

Speaker 1 of 5
* Simeon Taylor, University of Maryland School of Medicine, USA

Tuesday, January 15 | 8:00AM - 11:00AM
Genetics of Diabetes and Obesity (Joint)
Room: Crestone/Red Cloud

Speaker 2 of 5
Philippe Froguel, Imperial College of London, UK
Genetics of Type 2 Diabetes and Obesity: Is There a Molecular Link?

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