Tuberculosis: Integrating Host and Pathogen Biology Organizer(s): Gilla Kaplan, Clifton E. Barry III and Stewart Cole Date: January 25 - 30, 2003
Location: Sagebrush Inn & Suites, Taos, NM, USAWith the completion of the genome sequence for both Mycobacterium tuberculosis and Homo sapiens the complexities of pathogen host interaction are now accessible for study. The aims of this meeting are: to review the latest insights obtained from analysis of the genome sequence of M. tuberculosis; to dissect the cell biology of the interaction between M. tuberculosis and host cells; to understand the physiology of the pathogen and identify novel targets for drug development; to discuss the molecular basis of M. tuberculosis strain differences and the implications for transmission and immunity; to explore mechanisms of pathogenesis; to learn how the host develops protective immunity against the pathogen; and to develop strategies for manipulation of the host response to tuberculosis through vaccine development. The stimulating discussion among epidemiologists, cell biologists, immunologists, microbial geneticists, and biotechnologists will define the direction of research and accelerate the development of new therapies, diagnostics, and vaccines and promote the forging of new collaborative efforts. We gratefully acknowledge additional support for this conference from:  |