PPARs: Transcriptional Regulators of Metabolism and Metabolic Disease
Organizer(s): Ronald M. Evans, Bruce M. Spiegelman and Christopher K. GlassDate: February 04 - 09, 2003
Location: Keystone Resort, Keystone, CO, USA
· To review recent findings that focus attention on PPARs as key targets in the pathogenicity of obesity, diabetes, atherosclerosis and cancer. Also, genetic alterations in PPARs in humans with diabetes/lipodystrophy syndrome and cancer. · To describe insights from new animal models and clinical studies that relate to an emerging biology of lipid metabolism and inflammation and disease. · To identify the transcriptional basis of these phenomena by the identification of PPAR target genes. · To dissect the mechanism(s) by which PPAR active drugs modulate cancer, affect heart disease, and function as anti-diabetic compounds. · To explore the recent links between the action of the PPARs with other nuclear receptors such as LXR and implications for cholesterol metabolism. · To foster new insights that will lead to novel and effective insights to the origin and treatment of PPAR related disease. · To develop new collaborations among the scientists in attendance.
Discounted Abstract Deadline: October 3 2002
Discounted Registration Deadline: December 4 2002
We gratefully acknowledge additional support for this conference from:
Affinity BioReagents, Inc.