Transposition and Other Genome Rearrangements
Organizer(s): Tania A. Baker, Ronald Plasterk, Daniel F. VoytasDate: February 08 - 14, 2003
Location: Hilton Santa Fe Historic Plaza Hotel, Santa Fe, NM, USA
Transposons are a powerful creative force. The recent sequence of the human genome reveals that 45% of the DNA and about 50 genes appear to be transposon-derived. Transposition and related recombination reactions are responsible for generating antibody diversity, altering antigen expression, integration of retroviruses, and the horizontal transmission of virulence factors. Current research is aimed at understanding: (1) recombination mechanisms, using biochemical and structural approaches; (2) their regulation by the environment and during development; and (3) how these events affect cellular function and organism evolution. In this post-genomic era, transposition and site-specific recombination have also been embraced as tools for genome analysis and manipulation. This meeting will bring together researchers interested in all aspects of specialized recombination, from the biological to the structural and mechanistic. Research probing recombination in diverse organisms--including microbes, plants, and animals--will be presented to facilitate exchange of information and ideas, and encourage participants to reach out in new directions.
Discounted Abstract Deadline: October 8 2002
Discounted Registration Deadline: December 9 2002