Dynamics of Cellular Organization
Organizer(s): Jennifer A. Lippincott-Schwartz and David L. SpectorDate: February 22 - 27, 2003
Location: Sagebrush Inn & Suites, Taos, NM, USA
Some of the most basic features of biological organization are now being unraveled using live cell imaging approaches that analyze the spatio-temporal behavior of molecules in cells. These approaches are providing a dynamic view of protein behavior in cells that integrates information on protein localization, concentration, diffusion and interactions that are indiscernible from protein sequences and in vitro biochemical experiments alone. Precise measurement and analysis of fluorescently labeled proteins in cells has revealed, for example, that nuclear architecture is extremely dynamic and comprised of steady-state assemblies of molecules that undergo cell cycle dependent changes in distributions. It has provided insight into the self-organizing properties of the cytoplasm and membrane lipid/protein assemblies. In addition, it is helping to clarify intracellular pathways of protein trafficking, mechanisms of cell motility, the generation of cell polarity, signaling networks and cell responses to stress. A major challenge now is to understand how these dynamic cellular processes are integrated into hierarchically organized cellular systems that give rise to global cell function. The goal of this meeting is to bring together investigators from different areas of cell biology who utilize live cell experimental and theoretical approaches to discuss fundamental principles governing protein geography and movement within cells and how they subserve broader, integrative cellular functions.
Discounted Abstract Deadline: October 22 2002
Discounted Registration Deadline: December 23 2002
We gratefully acknowledge additional support for this conference from: