RNA Trafficking, Transport and Processing
Organizer(s): Anne Ephrussi, Iain W. Mattaj and Gideon DreyfussDate: April 05 - 10, 2003
Location: Snowbird Resort, Snowbird, UT, USA
Recent exciting developments in the field of RNA transport include the revelation that RNA processing, exit from the nucleus and identification in the cytoplasm are related processes, mediated by highly dynamic protein-RNA interactions. Proteins deposited on RNAs co-transcriptionally and through splicing appear to be critical to the subsequent fate of mRNA. Although their functions and to some extent even their identities are not clear, these proteins determine the properties of the mRNA with which they associate. They affect the nuclear export, stability and likely other cytoplasmic aspects of the life of an mRNA. The nuclear RNP remodeling events, how very large mRNP complexes get through the nuclear pore, how they associate with the cytoskeletal components required for their localization, how specificity of localization is determined and how translational repression of the unlocalized mRNA and local translational activation are achieved are now among the central questions. The goal of the meeting is to bring together scientists working at each level in the metabolism of mRNA, from it's co-transcriptional processing to its eventual translation and stability properties. It is at the interfaces between these different sub-disciplines that we hope to encourage interaction and progress.
Discounted Abstract Deadline: December 5 2002
Discounted Registration Deadline: February 5 2003