Regulatory and Effector Functions of Macrophages
joint with Linking Innate with Adaptive Immune Responses
Organizer(s): David M. Mosser, Christopher L. Karp and Siamon GordonDate: January 30 - February 04, 2003
Location: Taos Convention Center (meeting only), Taos, NM, USA
Macrophages occupy a unique niche in the immune system, in that they not only can initiate immune responses but they can also be effector cells which contribute to the resolution of these responses. The immunologic activation of macrophages can cause dramatic differences in their physiology. It is now well-appreciated that there is no single activation phenotype, and that macrophages can be induced to differentiate into cells that either exacerbate or inhibit inflammation. Similarly, these cells can promote, deviate, or suppress adaptive immune responses. The various states of macrophage activation and the mechanism of their induction will be examined. These discussions should lead to a better understanding of how specific alterations in macrophage physiology can contribute to or ameliorate inflammation, immune deviation, and the elimination of microbial pathogens.
Discounted Abstract Deadline: September 30 2002
Discounted Registration Deadline: December 2 2002