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Web Desc
G-Protein-Coupled Receptors: Evolving Concepts and Drug Discovery
Organizer(s): Paul A. Insel and Graeme Milligan
Date: February 17 - 22, 2004
Location: Taos Convention Center (meeting only), Taos, NM, USA
Sponsored by Aventis Pharmaceuticals, Inc.
Summary of Meeting:
G-protein-coupled receptors (GPCRs), which comprise one of the largest gene families identified in the human genome, also represent the largest number of currently used targets of therapeutic drugs. Recent work has indicated a number of intriguing observations in terms of GPCR structure, function and regulation, including existence of receptor homodimers and heterodimers, genetic identification of orphan GPCRs, novel receptor interacting proteins, clinically important polymorphisms and receptor mutations, mechanisms involved in receptor deactivation/desensitization, and receptor targeting/action in signaling microdomains. Definitive information about each of these topics is still being developed. This symposium will focus on these and related topics with an emphasis on use of new tools, e.g., bioinformatic approaches to evaluate GPCR family members, novel strategies to identify ligands active at GPCRs, and insights from non-mammalian/lower eukaryotic systems. Attendees will thus have the chance to learn and discuss new cutting-edge topics regarding GPCRs.
Discounted Abstract Deadline: October 16 2003
Discounted Registration Deadline: December 17 2003
We gratefully acknowledge additional support for this conference from:
Sanofi US
Synaptic Pharmaceutical Corp.
We gratefully acknowledge the generous grant for this conference provided by:

National Institute on Drug Abuse (NIDA)
Grant No. 1R13DA017912-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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