Apoptosis in Development
joint with Apoptosis in Biochemistry and Structural Biology
Organizer(s): Michael O. Hengartner, Sally A. Kornbluth and Scott W. LoweDate: February 03 - 08, 2004
Location: Keystone Resort, Keystone, CO, USA
The importance of apoptosis in disease development is well documented. However, its role in normal development is still lagging. Nevertheless, it is clear that apoptosis plays a crucial role in development, and that pathways that mediate developmental apoptosis are often mutated in disease. We now have a quite good understanding of the identity of the proteins that mediate apoptotic cell death. What are the roles of these proteins in normal development? How similar are the programs that mediate apoptotic cell death in different tissues? How similar are the death programs in different species? Many of the apoptotic proteins are conserved through evolution. Can one thus use information gained in one species to learn about apoptosis regulation in other species? Is apoptosis the only type of programmed cell death used during development in mammals? In other species? By bringing together scientists working on the same problem but in different systems (tissues and/or species), this meeting aims to: - Allow attendees to discern which genes and aspects of apoptosis are fundamental, and which might be system-specific. - Increase the transfer of knowledge between experimental systems - such that 'rules' established in one system can be tested and verified in others. - Encourage the study of apoptosis in development to better understand apoptotic pathways that can be altered in disease states.
Discounted Abstract Deadline: October 2 2003
Discounted Registration Deadline: December 3 2003
We gratefully acknowledge additional support for this conference from: