Ubiquitin and Signaling
Organizer(s): Tony Hunter, Claudio Joazeiro and Mark HochstrasserDate: February 22 - 27, 2005
Location: Taos Convention Center (meeting only), Taos, NM, USA
Our understanding of how ubiquitin regulates cellular function has greatly expanded recently, spurred by discoveries of protein families involved in ubiquitin conjugation and de-conjugation and of non-proteasomal signaling functions for ubiquitin. Ubiquitin regulates an enormous range of cellular processes. There are almost as many predicted human ubiquitin ligases as protein kinases, and the ubiquitin system has been directly implicated in various diseases, including many cancers and neurodegenerative disorders. Many protein domains have recently been associated with ubiquitination, deubiquitination or ubiquitin binding. These are found in several thousand proteins; the challenge is to determine their functions and mechanistic links to the ubiquitin system. The goal of the meeting is to bring together experts from different areas of ubiquitin research, as well as experts from other fields that are beginning to be affected by our knowledge of ubiquitin function. We expect that this meeting will foster extensive discussion of ubiquitin system function in both normal and pathological states.
Discounted Abstract Deadline: October 21 2004
Discounted Registration Deadline: December 22 2004
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
Regeneron Pharmaceuticals, Inc.