Tuberculosis: Integrating Host and Pathogen Biology Organizer(s): Gilla Kaplan, Clifton Barry III and Stewart Cole Date: April 02 - 07, 2005 Location: Whistler Conference Centre, Whistler, BC, CanadaTuberculosis is the leading infectious cause of mortality in the world today with 4 million deaths predicted for the year 2004. With the completion of the genome sequence of both Mycobacterium tuberculosis and Homo sapiens it is now possible to elucidate the dynamic interaction between the pathogen and its human host. Contemporary tools and novel technologies are currently being used to explore the molecular mechanisms that underlie host resistance and susceptibility, microbial drug resistance, the metabolic adaptations of the organism to latency and reactivation, and mechanisms of microbial pathogenesis. Recent studies have highlighted the importance of microbial regulatory systems and cell wall lipids in determining the ultimate outcome of infection. The development of novel vaccine candidates based on an understanding of the host response to infection has been facilitated by recent scientific advances. The aim of this meeting is to review the latest knowledge in these diverse fields of research and to provide an open forum for discussion and collaboration for scientists from the various disciplines required to control this disease. Discounted Abstract Deadline: December 2 2004 Discounted Registration Deadline: February 2 2005 We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
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