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Web Desc
Molecular Targets for Cancer Prevention
Organizer(s): Scott M. Lippman, Nancy H. Colburn and Andrew J. Dannenberg
Date: March 06 - 10, 2006
Location: Granlibakken Tahoe, Tahoe City, CA, USA
Supported by The Director's Fund
Summary of Meeting:
The most promising directions in cancer prevention lie in the early identification of high-risk individuals and the development of targeted interventions to prevent or delay carcinogenesis. A revolution in molecular studies and drug development has blurred the distinction between malignancy and pre-malignancy and between cancer therapy and prevention. Molecular targeted agents have produced major clinical advances in randomized controlled cancer prevention trials. Inflammation and obesity have emerged as important risk factors and provide new molecular targets for prevention such as HIF-1 and IGF-1. Molecular studies of fatty acid metabolism and stromal-epithelial interactions in carcinogenesis have identified targets such as cyclooxygenases, lipoxygenases, ECM proteases, and TGF-beta. Translation joins transcription as a new gene-regulation target for interventions; translationally regulated targets include c-myc and ODC. Imaging and proteomics have revealed new biomarkers that enable the early detection of cancer and enable more effective monitoring of drug effects in cancer prevention trials.
Scholarship Deadline: November 7 2005
Discounted Abstract Deadline: November 7 2005
Abstract Deadline: November 29 2005
Discounted Registration Deadline: January 6 2006
We gratefully acknowledge additional support for this conference from:
Novartis Institutes for BioMedical Research
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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